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G
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Ache
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acetylcholinesterase
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multiple interactions increases activity
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EXP
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Ascorbic Acid inhibits the reaction [Sodium Benzoate results in increased activity of ACHE protein]
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CTD |
PMID:35187746 |
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NCBI chr12:25,042,882...25,050,608
Ensembl chr12:19,407,360...19,413,651
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G
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Acta2
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actin alpha 2, smooth muscle
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multiple interactions
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ISO
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Sodium Benzoate inhibits the reaction [arsenite results in increased expression of ACTA2 protein]
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CTD |
PMID:38703806 |
|
NCBI chr 1:241,159,723...241,172,503
Ensembl chr 1:231,746,548...231,759,554
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G
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Ahr
|
aryl hydrocarbon receptor
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multiple interactions
|
ISO
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Sodium Benzoate inhibits the reaction [[DAO protein results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA]
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CTD |
PMID:19860415 |
|
NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:52,234,089...52,271,568
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G
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Camk2a
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calcium/calmodulin-dependent protein kinase II alpha
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multiple interactions
|
EXP
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Sodium Benzoate promotes the reaction [Cocaine results in increased phosphorylation of and results in increased activity of CAMK2A protein]
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CTD |
PMID:17609678 |
|
NCBI chr18:56,648,779...56,711,505
Ensembl chr18:54,378,784...54,438,994
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G
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Casp3
|
caspase 3
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multiple interactions increases activity increases expression
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ISO EXP
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Sodium Benzoate inhibits the reaction [Asbestos, Amosite results in increased activity of CASP3 protein] Sodium Benzoate results in increased activity of CASP3 protein Ascorbic Acid inhibits the reaction [Sodium Benzoate results in increased expression of CASP3 protein]
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CTD |
PMID:11329530 PMID:32911041 PMID:35187746 |
|
NCBI chr16:52,395,539...52,413,794
Ensembl chr16:45,662,910...45,684,648
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G
|
Casp9
|
caspase 9
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multiple interactions
|
ISO
|
Sodium Benzoate inhibits the reaction [Asbestos, Amosite results in increased activity of CASP9 protein]
|
CTD |
PMID:12540492 |
|
Ensembl chr 5:154,109,046...154,126,626
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G
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Cat
|
catalase
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decreases activity multiple interactions
|
EXP
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Sodium Benzoate results in decreased activity of CAT protein Ascorbic Acid inhibits the reaction [Sodium Benzoate results in decreased activity of CAT protein]
|
CTD |
PMID:32911041 PMID:35187746 |
|
NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:89,842,399...89,874,478
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G
|
Col1a1
|
collagen type I alpha 1 chain
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multiple interactions
|
ISO
|
Sodium Benzoate inhibits the reaction [arsenite results in increased expression of COL1A1 protein]
|
CTD |
PMID:38703806 |
|
NCBI chr10:80,380,458...80,397,461
Ensembl chr10:79,883,622...79,900,624
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|
G
|
Col3a1
|
collagen type III alpha 1 chain
|
multiple interactions
|
ISO
|
Sodium Benzoate inhibits the reaction [arsenite results in increased expression of COL3A1 protein]
|
CTD |
PMID:38703806 |
|
NCBI chr 9:54,866,646...54,902,578
Ensembl chr 9:47,374,593...47,410,547
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|
G
|
Cps1
|
carbamoyl-phosphate synthase 1
|
multiple interactions
|
ISO
|
Sodium Benzoate inhibits the reaction [arsenite results in increased expression of CPS1 protein]
|
CTD |
PMID:38703806 |
|
NCBI chr 9:68,614,153...68,737,037
Ensembl chr 9:68,614,153...68,737,033
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|
G
|
Cyp1a1
|
cytochrome P450, family 1, subfamily a, polypeptide 1
|
multiple interactions
|
ISO
|
Sodium Benzoate inhibits the reaction [[DAO protein results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA]
|
CTD |
PMID:19860415 |
|
NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:58,096,077...58,102,125
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|
G
|
Dao
|
D-amino-acid oxidase
|
multiple interactions decreases activity
|
ISO EXP
|
Sodium Benzoate inhibits the reaction [[DAO protein results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA] Sodium Benzoate results in decreased activity of DAO protein
|
CTD |
PMID:19860415 PMID:20952482 |
|
NCBI chr12:42,592,342...42,613,046
Ensembl chr12:42,592,343...42,612,741
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|
G
|
Esr1
|
estrogen receptor 1
|
decreases activity
|
ISO
|
Sodium Benzoate results in decreased activity of ESR1 protein
|
CTD |
PMID:22562034 |
|
NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:41,210,475...41,495,002
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|
G
|
Fshb
|
follicle stimulating hormone subunit beta
|
increases expression
|
EXP
|
Sodium Benzoate results in increased expression of FSHB protein
|
CTD |
PMID:32911041 |
|
NCBI chr 3:114,003,262...114,007,072
Ensembl chr 3:93,548,560...93,552,370
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|
G
|
Ifng
|
interferon gamma
|
multiple interactions
|
ISO EXP
|
Sodium Benzoate inhibits the reaction [Lipopolysaccharides results in increased secretion of IFNG protein] [Food Preservatives results in increased abundance of Sodium Benzoate] which results in increased expression of IFNG mRNA
|
CTD |
PMID:26706697 PMID:32179172 |
|
NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:53,903,337...53,907,375
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|
G
|
Il10
|
interleukin 10
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multiple interactions
|
EXP
|
[Food Preservatives results in increased abundance of Sodium Benzoate] which results in increased expression of IL10 mRNA
|
CTD |
PMID:32179172 |
|
NCBI chr13:45,024,921...45,029,586
Ensembl chr13:42,472,839...42,477,313
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G
|
Il1b
|
interleukin 1 beta
|
multiple interactions
|
EXP
|
[Food Preservatives results in increased abundance of Sodium Benzoate] which results in increased expression of IL1B mRNA
|
CTD |
PMID:32179172 |
|
NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:116,577,010...116,583,415
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G
|
Il6
|
interleukin 6
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multiple interactions increases expression
|
ISO EXP
|
Sodium Benzoate inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein] Sodium Benzoate results in increased expression of IL6 protein [Food Preservatives results in increased abundance of Sodium Benzoate] which results in increased expression of IL6 mRNA
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CTD |
PMID:26706697 PMID:32179172 PMID:32911041 |
|
NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,213,394...5,219,178
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|
G
|
Lhb
|
luteinizing hormone subunit beta
|
increases expression
|
EXP
|
Sodium Benzoate results in increased expression of LHB protein
|
CTD |
PMID:32911041 |
|
NCBI chr 1:105,037,457...105,038,446
Ensembl chr 1:95,900,984...95,901,972 Ensembl chr 1:95,900,984...95,901,972
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G
|
Msr1
|
macrophage scavenger receptor 1
|
multiple interactions
|
ISO
|
Sodium Benzoate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MSR1 mRNA alternative form]; Sodium Benzoate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MSR1 mRNA]
|
CTD |
PMID:9614211 |
|
NCBI chr16:52,717,775...52,803,602
Ensembl chr16:52,717,732...52,799,676
|
|
G
|
Otc
|
ornithine transcarbamylase
|
multiple interactions
|
ISO
|
Sodium Benzoate affects the reaction [OTC gene mutant form affects the abundance of Hydroxyindoleacetic Acid]; Sodium Benzoate affects the reaction [OTC gene mutant form affects the metabolism of Glycine]; Sodium Benzoate affects the reaction [OTC gene mutant form affects the metabolism of Serotonin]; Sodium Benzoate affects the reaction [OTC gene mutant form results in increased abundance of Ammonium Compounds]
|
CTD |
PMID:3091026 PMID:3374991 |
|
NCBI chr X:12,453,834...12,529,954
Ensembl chr X:12,453,834...12,566,918
|
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G
|
Tfam
|
transcription factor A, mitochondrial
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increases expression
|
EXP
|
Sodium Benzoate results in increased expression of TFAM protein
|
CTD |
PMID:32911041 |
|
NCBI chr20:17,355,373...17,367,422
Ensembl chr20:17,356,197...17,368,292
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|
G
|
Tnf
|
tumor necrosis factor
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multiple interactions increases expression
|
ISO EXP
|
Sodium Benzoate inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein] Sodium Benzoate results in increased expression of TNF protein [Food Preservatives results in increased abundance of Sodium Benzoate] which results in increased expression of TNF mRNA; Ascorbic Acid inhibits the reaction [Sodium Benzoate results in increased expression of TNF protein]
|
CTD |
PMID:26706697 PMID:32179172 PMID:32911041 PMID:35187746 |
|
NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,622,011...3,624,629
|
|
G
|
Tp53
|
tumor protein p53
|
multiple interactions increases expression
|
ISO EXP
|
Sodium Benzoate inhibits the reaction [Asbestos, Amosite results in increased expression of TP53 mRNA] Sodium Benzoate results in increased expression of TP53 protein
|
CTD |
PMID:16357363 PMID:32911041 |
|
NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,300,048...54,311,524
|
|
G
|
Ucp2
|
uncoupling protein 2
|
increases expression
|
EXP
|
Sodium Benzoate results in increased expression of UCP2 protein
|
CTD |
PMID:32911041 |
|
NCBI chr 1:164,251,373...164,257,742
Ensembl chr 1:154,839,209...154,845,611
|
|
G
|
Vim
|
vimentin
|
multiple interactions
|
ISO
|
Sodium Benzoate inhibits the reaction [arsenite results in increased expression of VIM protein]
|
CTD |
PMID:38703806 |
|
NCBI chr17:81,577,261...81,585,746
Ensembl chr17:76,668,647...76,677,187
|
|
G
|
Xdh
|
xanthine dehydrogenase
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increases activity
|
EXP
|
Sodium Benzoate results in increased activity of XDH protein
|
CTD |
PMID:32911041 |
|
NCBI chr 6:27,282,319...27,344,022
Ensembl chr 6:21,530,113...21,592,268
|
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