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G |
Ache |
acetylcholinesterase |
multiple interactions increases activity |
EXP |
Ascorbic Acid inhibits the reaction [Sodium Benzoate results in increased activity of ACHE protein] |
CTD |
PMID:35187746 |
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NCBI chr12:19,407,359...19,413,713
Ensembl chr12:19,407,360...19,413,651
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G |
Ahr |
aryl hydrocarbon receptor |
multiple interactions |
ISO |
Sodium Benzoate inhibits the reaction [[DAO protein results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA] |
CTD |
PMID:19860415 |
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NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
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G |
Camk2a |
calcium/calmodulin-dependent protein kinase II alpha |
multiple interactions |
EXP |
Sodium Benzoate promotes the reaction [Cocaine results in increased phosphorylation of and results in increased activity of CAMK2A protein] |
CTD |
PMID:17609678 |
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NCBI chr18:54,378,642...54,441,120
Ensembl chr18:54,378,784...54,438,994
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G |
Casp3 |
caspase 3 |
multiple interactions increases activity increases expression |
ISO EXP |
Sodium Benzoate inhibits the reaction [Asbestos, Amosite results in increased activity of CASP3 protein] Sodium Benzoate results in increased activity of CASP3 protein Ascorbic Acid inhibits the reaction [Sodium Benzoate results in increased expression of CASP3 protein] |
CTD |
PMID:11329530 PMID:32911041 PMID:35187746 |
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NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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G |
Casp9 |
caspase 9 |
multiple interactions |
ISO |
Sodium Benzoate inhibits the reaction [Asbestos, Amosite results in increased activity of CASP9 protein] |
CTD |
PMID:12540492 |
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NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
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G |
Cat |
catalase |
decreases activity multiple interactions |
EXP |
Sodium Benzoate results in decreased activity of CAT protein Ascorbic Acid inhibits the reaction [Sodium Benzoate results in decreased activity of CAT protein] |
CTD |
PMID:32911041 PMID:35187746 |
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NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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G |
Cyp1a1 |
cytochrome P450, family 1, subfamily a, polypeptide 1 |
multiple interactions |
ISO |
Sodium Benzoate inhibits the reaction [[DAO protein results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA] |
CTD |
PMID:19860415 |
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NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
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G |
Dao |
D-amino-acid oxidase |
multiple interactions decreases activity |
ISO EXP |
Sodium Benzoate inhibits the reaction [[DAO protein results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA] Sodium Benzoate results in decreased activity of DAO protein |
CTD |
PMID:19860415 PMID:20952482 |
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NCBI chr12:42,592,342...42,613,046
Ensembl chr12:42,592,343...42,612,741
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G |
Esr1 |
estrogen receptor 1 |
decreases activity |
ISO |
Sodium Benzoate results in decreased activity of ESR1 protein |
CTD |
PMID:22562034 |
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NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
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G |
Fshb |
follicle stimulating hormone subunit beta |
increases expression |
EXP |
Sodium Benzoate results in increased expression of FSHB protein |
CTD |
PMID:32911041 |
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NCBI chr 3:93,548,560...93,552,370
Ensembl chr 3:93,548,560...93,552,370
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G |
Ifng |
interferon gamma |
multiple interactions |
ISO EXP |
Sodium Benzoate inhibits the reaction [Lipopolysaccharides results in increased secretion of IFNG protein] [Food Preservatives results in increased abundance of Sodium Benzoate] which results in increased expression of IFNG mRNA |
CTD |
PMID:26706697 PMID:32179172 |
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NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
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G |
Il10 |
interleukin 10 |
multiple interactions |
EXP |
[Food Preservatives results in increased abundance of Sodium Benzoate] which results in increased expression of IL10 mRNA |
CTD |
PMID:32179172 |
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NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
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G |
Il1b |
interleukin 1 beta |
multiple interactions |
EXP |
[Food Preservatives results in increased abundance of Sodium Benzoate] which results in increased expression of IL1B mRNA |
CTD |
PMID:32179172 |
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NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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G |
Il6 |
interleukin 6 |
multiple interactions increases expression |
ISO EXP |
Sodium Benzoate inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein] Sodium Benzoate results in increased expression of IL6 protein [Food Preservatives results in increased abundance of Sodium Benzoate] which results in increased expression of IL6 mRNA |
CTD |
PMID:26706697 PMID:32179172 PMID:32911041 |
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NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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G |
Lhb |
luteinizing hormone subunit beta |
increases expression |
EXP |
Sodium Benzoate results in increased expression of LHB protein |
CTD |
PMID:32911041 |
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NCBI chr 1:95,898,269...95,901,973
Ensembl chr 1:95,900,984...95,901,972 Ensembl chr 1:95,900,984...95,901,972
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G |
Msr1 |
macrophage scavenger receptor 1 |
multiple interactions |
ISO |
Sodium Benzoate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MSR1 mRNA alternative form]; Sodium Benzoate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MSR1 mRNA] |
CTD |
PMID:9614211 |
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NCBI chr16:52,717,775...52,802,890
Ensembl chr16:52,717,732...52,799,676
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G |
Otc |
ornithine transcarbamylase |
multiple interactions |
ISO |
Sodium Benzoate affects the reaction [OTC gene mutant form affects the abundance of Hydroxyindoleacetic Acid]; Sodium Benzoate affects the reaction [OTC gene mutant form affects the metabolism of Glycine]; Sodium Benzoate affects the reaction [OTC gene mutant form affects the metabolism of Serotonin]; Sodium Benzoate affects the reaction [OTC gene mutant form results in increased abundance of Ammonium Compounds] |
CTD |
PMID:3091026 PMID:3374991 |
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NCBI chr X:12,453,834...12,529,954
Ensembl chr X:12,453,834...12,566,918
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G |
Tfam |
transcription factor A, mitochondrial |
increases expression |
EXP |
Sodium Benzoate results in increased expression of TFAM protein |
CTD |
PMID:32911041 |
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NCBI chr20:17,356,243...17,368,293
Ensembl chr20:17,356,197...17,368,292
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G |
Tnf |
tumor necrosis factor |
multiple interactions increases expression |
ISO EXP |
Sodium Benzoate inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein] Sodium Benzoate results in increased expression of TNF protein [Food Preservatives results in increased abundance of Sodium Benzoate] which results in increased expression of TNF mRNA; Ascorbic Acid inhibits the reaction [Sodium Benzoate results in increased expression of TNF protein] |
CTD |
PMID:26706697 PMID:32179172 PMID:32911041 PMID:35187746 |
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NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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G |
Tp53 |
tumor protein p53 |
multiple interactions increases expression |
ISO EXP |
Sodium Benzoate inhibits the reaction [Asbestos, Amosite results in increased expression of TP53 mRNA] Sodium Benzoate results in increased expression of TP53 protein |
CTD |
PMID:16357363 PMID:32911041 |
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NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
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G |
Ucp2 |
uncoupling protein 2 |
increases expression |
EXP |
Sodium Benzoate results in increased expression of UCP2 protein |
CTD |
PMID:32911041 |
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NCBI chr 1:154,839,242...154,845,612
Ensembl chr 1:154,839,209...154,845,611
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G |
Xdh |
xanthine dehydrogenase |
increases activity |
EXP |
Sodium Benzoate results in increased activity of XDH protein |
CTD |
PMID:32911041 |
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NCBI chr 6:21,530,463...21,592,172
Ensembl chr 6:21,530,113...21,592,268
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