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ONTOLOGY REPORT - ANNOTATIONS


Term:clodronic acid
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Accession:CHEBI:110423 term browser browse the term
Definition:An organochlorine compound that is methylene chloride in which both hydrogens are replaced by phosphonic acid groups. It inhibits bone resorption and soft tissue calcification, and is used (often as the disodium salt tetrahydrate) as an adjunct in the treatment of severe hypercalcaemia associated with malignancy, and in the management of osteolytic lesions and bone pain associated with skeletal metastases.
Synonyms:exact_synonym: (dichloromethanediyl)bis(phosphonic acid)
 related_synonym: (Dichloro-phosphono-methyl)-phosphonic acid;   (dichloromethylene)bisphosphonic acid;   (dichloromethylene)diphosphonic acid;   Formula=CH4Cl2O6P2;   InChI=1S/CH4Cl2O6P2/c2-1(3,10(4,5)6)11(7,8)9/h(H2,4,5,6)(H2,7,8,9);   InChIKey=ACSIXWWBWUQEHA-UHFFFAOYSA-N;   SMILES=OP(O)(=O)C(Cl)(Cl)P(O)(O)=O;   acide clodronique;   acido clodronico;   acidum clodronicum;   clodronate;   clodronsaeure;   dichloromethylene-1,1-bisphosphonic acid;   dichloromethylene-1,1-diphosphonic acid;   dichloromethylidene diphosphonate
 xref: Beilstein:1876367 "Beilstein";   CAS:10596-23-3 "ChemIDplus";   DrugBank:DB00720;   Drug_Central:690 "DrugCentral";   KEGG:D03545;   LINCS:LSM-5802
 xref_mesh: MESH:D004002
 xref: PMID:15658873 "ChEMBL";   PMID:7818726 "ChEMBL";   PMID:8421279 "ChEMBL";   Patent:BE672205
 cyclic_relationship: is_conjugate_acid_of CHEBI:59585


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clodronic acid term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aars alanyl-tRNA synthetase JBrowse link 8 111,027,778 111,055,569 RGD:6480464
G Abcb9 ATP-binding cassette, sub-family B (MDR/TAP), member 9 JBrowse link 5 124,061,857 124,095,955 RGD:6480464
G Abcc3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 JBrowse link 11 94,343,295 94,393,017 RGD:6480464
G Abcg1 ATP binding cassette subfamily G member 1 JBrowse link 17 31,057,694 31,117,984 RGD:6480464
G Abhd4 abhydrolase domain containing 4 JBrowse link 14 54,254,129 54,269,169 RGD:6480464
G Acsl1 acyl-CoA synthetase long-chain family member 1 JBrowse link 8 46,471,037 46,536,051 RGD:6480464
G Acta2 actin, alpha 2, smooth muscle, aorta JBrowse link 19 34,240,336 34,255,585 RGD:6480464
G Agrn agrin JBrowse link 4 156,165,290 156,197,533 RGD:6480464
G Ahr aryl-hydrocarbon receptor JBrowse link 12 35,497,979 35,534,989 RGD:6480464
G Aifm2 apoptosis-inducing factor, mitochondrion-associated 2 JBrowse link 10 61,715,263 61,739,260 RGD:6480464
G Ak3 adenylate kinase 3 JBrowse link 19 28,995,053 29,048,080 RGD:6480464
G Akr1c21 aldo-keto reductase family 1, member C21 JBrowse link 13 4,574,075 4,586,543 RGD:6480464
G Aldh1a3 aldehyde dehydrogenase family 1, subfamily A3 JBrowse link 7 66,390,892 66,427,477 RGD:6480464
G Aldoa aldolase A, fructose-bisphosphate JBrowse link 7 126,795,234 126,800,994 RGD:6480464
G Als2cl ALS2 C-terminal like JBrowse link 9 110,880,120 110,900,530 RGD:6480464
G Angptl4 angiopoietin-like 4 JBrowse link 17 33,774,900 33,781,575 RGD:6480464
G Ankra2 ankyrin repeat, family A (RFXANK-like), 2 JBrowse link 13 98,263,076 98,274,754 RGD:6480464
G Arfgef2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) JBrowse link 2 166,805,451 166,898,052 RGD:6480464
G Arhgef10 Rho guanine nucleotide exchange factor (GEF) 10 JBrowse link 8 14,906,412 15,001,085 RGD:6480464
G Arl1 ADP-ribosylation factor-like 1 JBrowse link 10 88,730,920 88,744,094 RGD:6480464
G Asns asparagine synthetase JBrowse link 6 7,675,165 7,693,209 RGD:6480464
G Astn2 astrotactin 2 JBrowse link 4 65,380,803 66,404,537 RGD:6480464
G Atad2 ATPase family, AAA domain containing 2 JBrowse link 15 58,094,044 58,135,525 RGD:6480464
G Atf3 activating transcription factor 3 JBrowse link 1 191,170,296 191,183,333 RGD:6480464
G Atf4 activating transcription factor 4 JBrowse link 15 80,255,184 80,257,545 RGD:6480464
G Atxn1 ataxin 1 JBrowse link 13 45,549,755 45,964,991 RGD:6480464
G Aurkb aurora kinase B JBrowse link 11 69,045,624 69,051,664 RGD:6480464
G Axl AXL receptor tyrosine kinase JBrowse link 7 25,756,500 25,788,924 RGD:6480464
G Batf basic leucine zipper transcription factor, ATF-like JBrowse link 12 85,686,720 85,709,087 RGD:6480464
G Bax BCL2-associated X protein JBrowse link 7 45,461,695 45,466,903 RGD:6480464
G Bcat1 branched chain aminotransferase 1, cytosolic JBrowse link 6 144,993,835 145,076,157 RGD:6480464
G Bcat2 branched chain aminotransferase 2, mitochondrial JBrowse link 7 45,568,967 45,589,710 RGD:6480464
G Bcl3 B cell leukemia/lymphoma 3 JBrowse link 7 19,808,462 19,822,824 RGD:6480464
G Bend5 BEN domain containing 5 JBrowse link 4 111,413,794 111,460,298 RGD:6480464
G Bnip3 BCL2/adenovirus E1B interacting protein 3 JBrowse link 7 138,890,836 138,909,506 RGD:6480464
G Brd2 bromodomain containing 2 JBrowse link 17 34,112,019 34,122,814 RGD:6480464
G Btg2 BTG anti-proliferation factor 2 JBrowse link 1 134,074,865 134,079,155 RGD:6480464
G Camkk2 calcium/calmodulin-dependent protein kinase kinase 2, beta JBrowse link 5 122,718,380 122,779,522 RGD:6480464
G Cars cysteinyl-tRNA synthetase JBrowse link 7 143,557,230 143,600,090 RGD:6480464
G Casp3 caspase 3 JBrowse link 8 46,617,291 46,639,698 RGD:6480464
G Ccdc90b coiled-coil domain containing 90B JBrowse link 7 92,561,149 92,582,294 RGD:6480464
G Ccne2 cyclin E2 JBrowse link 4 11,190,433 11,204,779 RGD:6480464
G Ccng2 cyclin G2 JBrowse link 5 93,267,573 93,276,231 RGD:6480464
G Cd68 CD68 antigen JBrowse link 11 69,664,213 69,666,170 RGD:6480464
G Cd80 CD80 antigen JBrowse link 16 38,457,430 38,495,958 RGD:6480464
G Cd86 CD86 antigen JBrowse link 16 36,568,956 36,666,158 RGD:6480464
G Cdk6 cyclin-dependent kinase 6 JBrowse link 5 3,341,004 3,531,008 RGD:6480464
G Cdkn1a cyclin-dependent kinase inhibitor 1A (P21) JBrowse link 17 29,090,979 29,100,722 RGD:6480464
G Cers5 ceramide synthase 5 JBrowse link 15 99,735,592 99,772,515 RGD:6480464
G Clip4 CAP-GLY domain containing linker protein family, member 4 JBrowse link 17 71,769,674 71,864,210 RGD:6480464
G Cmbl carboxymethylenebutenolidase-like (Pseudomonas) JBrowse link 15 31,565,342 31,590,119 RGD:6480464
G Col1a1 collagen, type I, alpha 1 JBrowse link 11 94,936,224 94,953,042 RGD:6480464
G Crispld2 cysteine-rich secretory protein LCCL domain containing 2 JBrowse link 8 119,992,438 120,052,794 RGD:6480464
G Ctdp1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 JBrowse link 18 80,407,959 80,478,739 RGD:6480464
G Cth cystathionase (cystathionine gamma-lyase) JBrowse link 3 157,894,248 157,925,081 RGD:6480464
G Ctsc cathepsin C JBrowse link 7 88,278,024 88,315,861 RGD:6480464
G Cttn cortactin JBrowse link 7 144,435,724 144,471,560 RGD:6480464
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 JBrowse link 9 57,676,937 57,683,655 RGD:6480464
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 JBrowse link 17 79,706,940 79,715,061 RGD:6480464
G Ddb2 damage specific DNA binding protein 2 JBrowse link 2 91,211,545 91,237,132 RGD:6480464
G Ddit3 DNA-damage inducible transcript 3 JBrowse link 10 127,290,793 127,296,291 RGD:6480464
G Ddit4 DNA-damage-inducible transcript 4 JBrowse link 10 59,949,675 59,951,770 RGD:6480464
G Ddx17 DEAD (Asp-Glu-Ala-Asp) box polypeptide 17 JBrowse link 15 79,527,696 79,546,764 RGD:6480464
G Des desmin JBrowse link 1 75,360,292 75,368,579 RGD:6480464
G Dgka diacylglycerol kinase, alpha JBrowse link 10 128,720,131 128,745,084 RGD:6480464
G Dhx37 DEAH (Asp-Glu-Ala-His) box polypeptide 37 JBrowse link 5 125,413,747 125,434,139 RGD:6480464
G Dlgap5 DLG associated protein 5 JBrowse link 14 47,387,779 47,418,407 RGD:6480464
G Dnajb9 DnaJ heat shock protein family (Hsp40) member B9 JBrowse link 12 44,205,897 44,210,068 RGD:6480464
G Dpm3 dolichyl-phosphate mannosyltransferase polypeptide 3 JBrowse link 3 89,257,065 89,267,079 RGD:6480464
G Dpysl3 dihydropyrimidinase-like 3 JBrowse link 18 43,320,979 43,438,286 RGD:6480464
G Dusp22 dual specificity phosphatase 22 JBrowse link 13 30,660,059 30,711,232 RGD:6480464
G Efna1 ephrin A1 JBrowse link 3 89,271,730 89,280,951 RGD:6480464
G Eif1 eukaryotic translation initiation factor 1 JBrowse link 11 100,319,949 100,322,099 RGD:6480464
G Eif2s2 eukaryotic translation initiation factor 2, subunit 2 (beta) JBrowse link 2 154,871,410 154,892,906 RGD:6480464
G Eif3c eukaryotic translation initiation factor 3, subunit C JBrowse link 7 126,546,911 126,566,366 RGD:6480464
G Elf4 E74-like factor 4 (ets domain transcription factor) JBrowse link X 48,411,049 48,463,132 RGD:6480464
G Elk4 ELK4, member of ETS oncogene family JBrowse link 1 132,007,565 132,026,448 RGD:6480464
G Eno2 enolase 2, gamma neuronal JBrowse link 6 124,760,053 124,769,673 RGD:6480464
G Ep400 E1A binding protein p400 JBrowse link 5 110,664,373 110,770,927 RGD:6480464
G Eprs glutamyl-prolyl-tRNA synthetase JBrowse link 1 185,361,417 185,428,360 RGD:6480464
G Fam162a family with sequence similarity 162, member A JBrowse link 16 36,043,844 36,071,561 RGD:6480464
G Fam210a family with sequence similarity 210, member A JBrowse link 18 68,260,175 68,300,333 RGD:6480464
G Fam214a family with sequence similarity 214, member A JBrowse link 9 74,952,867 75,032,468 RGD:6480464
G Fam89a family with sequence similarity 89, member A JBrowse link 8 124,740,257 124,751,866 RGD:6480464
G Fas Fas (TNF receptor superfamily member 6) JBrowse link 19 34,290,647 34,327,775 RGD:6480464
G Fbxo22 F-box protein 22 JBrowse link 9 55,208,935 55,224,433 RGD:6480464
G Fbxo30 F-box protein 30 JBrowse link 10 11,281,330 11,305,750 RGD:6480464
G Fech ferrochelatase JBrowse link 18 64,456,542 64,489,098 RGD:6480464
G Flvcr2 feline leukemia virus subgroup C cellular receptor 2 JBrowse link 12 85,746,539 85,813,586 RGD:6480464
G Fosl1 fos-like antigen 1 JBrowse link 19 5,447,698 5,455,938 RGD:6480464
G Fosl2 fos-like antigen 2 JBrowse link 5 32,136,472 32,157,840 RGD:6480464
G Frem2 Fras1 related extracellular matrix protein 2 JBrowse link 3 53,513,938 53,658,593 RGD:6480464
G Fth1 ferritin heavy polypeptide 1 JBrowse link 19 9,980,600 9,985,111 RGD:6480464
G Gabarapl1 gamma-aminobutyric acid (GABA) A receptor-associated protein-like 1 JBrowse link 6 129,533,192 129,542,331 RGD:6480464
G Gars glycyl-tRNA synthetase JBrowse link 6 55,038,001 55,079,504 RGD:6480464
G Gclc glutamate-cysteine ligase, catalytic subunit JBrowse link 9 77,754,535 77,794,489 RGD:6480464
G Gclm glutamate-cysteine ligase, modifier subunit JBrowse link 3 122,245,487 122,267,215 RGD:6480464
G Gdf15 growth differentiation factor 15 JBrowse link 8 70,629,393 70,632,470 RGD:6480464
G Gm20348 predicted gene, 20348 JBrowse link 12 4,810,475 4,817,155 RGD:6480464
G Golim4 golgi integral membrane protein 4 JBrowse link 3 75,876,183 75,956,956 RGD:6480464
G Gpat3 glycerol-3-phosphate acyltransferase 3 JBrowse link 5 100,845,665 100,899,102 RGD:6480464
G Gpnmb glycoprotein (transmembrane) nmb JBrowse link 6 49,036,518 49,058,182 RGD:6480464
G Gpr87 G protein-coupled receptor 87 JBrowse link 3 59,178,904 59,195,163 RGD:6480464
G Gpt glutamic pyruvic transaminase, soluble JBrowse link 15 76,696,726 76,699,675 RGD:6480464
G Gsr glutathione reductase JBrowse link 8 33,653,238 33,698,162 RGD:6480464
G Hif1a hypoxia inducible factor 1, alpha subunit JBrowse link 12 73,901,324 73,947,554 RGD:6480464
G Hmox1 heme oxygenase 1 JBrowse link 8 75,093,618 75,100,593 RGD:6480464
G Iars isoleucine-tRNA synthetase JBrowse link 13 49,682,130 49,734,267 RGD:6480464
G Icam1 intercellular adhesion molecule 1 JBrowse link 9 21,015,940 21,028,814 RGD:6480464
G Ids iduronate 2-sulfatase JBrowse link X 70,343,069 70,385,834 RGD:6480464
G Ifng interferon gamma JBrowse link 10 118,441,046 118,445,894 RGD:6480464
G Igf1r insulin-like growth factor I receptor JBrowse link 7 67,952,257 68,233,668 RGD:6480464
G Il1b interleukin 1 beta JBrowse link 2 129,364,569 129,371,164 RGD:6480464
G Il6 interleukin 6 JBrowse link 5 30,013,114 30,019,975 RGD:6480464
G Kdm3a lysine (K)-specific demethylase 3A JBrowse link 6 71,588,970 71,632,990 RGD:6480464
G Keap1 kelch-like ECH-associated protein 1 JBrowse link 9 21,229,730 21,239,332 RGD:6480464
G Lama3 laminin, alpha 3 JBrowse link 18 12,333,417 12,583,013 RGD:6480464
G Ltn1 listerin E3 ubiquitin protein ligase 1 JBrowse link 16 87,376,651 87,432,619 RGD:6480464
G Mafg v-maf musculoaponeurotic fibrosarcoma oncogene family, protein G (avian) JBrowse link 11 120,625,117 120,634,955 RGD:6480464
G Mapre2 microtubule-associated protein, RP/EB family, member 2 JBrowse link 18 23,752,333 23,893,861 RGD:6480464
G Mcoln2 mucolipin 2 JBrowse link 3 146,149,796 146,195,514 RGD:6480464
G Me1 malic enzyme 1, NADP(+)-dependent, cytosolic JBrowse link 9 86,581,363 86,695,914 RGD:6480464
G Mtdh metadherin JBrowse link 15 34,082,442 34,143,537 RGD:6480464
G Muc2 mucin 2 JBrowse link 7 141,690,340 141,754,694 RGD:6480464
G Mxi1 MAX interactor 1, dimerization protein JBrowse link 19 53,310,128 53,373,293 RGD:6480464
G Nars asparaginyl-tRNA synthetase JBrowse link 18 64,499,647 64,516,557 RGD:6480464
G Nedd9 neural precursor cell expressed, developmentally down-regulated gene 9 JBrowse link 13 41,309,916 41,487,362 RGD:6480464
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 JBrowse link 2 75,675,513 75,704,663 RGD:6480464
G Nin ninein JBrowse link 12 70,011,435 70,113,811 RGD:6480464
G Nqo1 NAD(P)H dehydrogenase, quinone 1 JBrowse link 8 107,388,225 107,403,205 RGD:6480464
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 JBrowse link 18 39,410,545 39,519,421 RGD:6480464
G Nrep neuronal regeneration related protein JBrowse link 18 33,437,019 33,464,365 RGD:6480464
G Ntpcr nucleoside-triphosphatase, cancer-related JBrowse link 8 125,729,975 125,748,235 RGD:6480464
G Nuak1 NUAK family, SNF1-like kinase, 1 JBrowse link 10 84,370,900 84,440,668 RGD:6480464
G Orai3 ORAI calcium release-activated calcium modulator 3 JBrowse link 7 127,769,815 127,775,150 RGD:6480464
G Osgin1 oxidative stress induced growth inhibitor 1 JBrowse link 8 119,425,882 119,446,257 RGD:6480464
G P4ha1 procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha 1 polypeptide JBrowse link 10 59,323,197 59,373,304 RGD:6480464
G Pde8a phosphodiesterase 8A JBrowse link 7 81,213,265 81,334,535 RGD:6480464
G Pdia5 protein disulfide isomerase associated 5 JBrowse link 16 35,397,308 35,490,919 RGD:6480464
G Pdk1 pyruvate dehydrogenase kinase, isoenzyme 1 JBrowse link 2 71,873,215 71,903,858 RGD:6480464
G Pdk4 pyruvate dehydrogenase kinase, isoenzyme 4 JBrowse link 6 5,483,351 5,496,278 RGD:6480464
G Pdlim1 PDZ and LIM domain 1 (elfin) JBrowse link 19 40,222,239 40,271,616 RGD:6480464
G Pfkfb4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 JBrowse link 9 108,988,272 109,032,236 RGD:6480464
G Phgdh 3-phosphoglycerate dehydrogenase JBrowse link 3 98,313,171 98,339,969 RGD:6480464
G Pip5k1c phosphatidylinositol-4-phosphate 5-kinase, type 1 gamma JBrowse link 10 81,292,835 81,319,974 RGD:6480464
G Pir pirin JBrowse link X 164,269,431 164,373,013 RGD:6480464
G Plec plectin JBrowse link 15 76,170,974 76,231,378 RGD:6480464
G Plk3 polo like kinase 3 JBrowse link 4 117,128,655 117,133,963 RGD:6480464
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 JBrowse link 18 66,458,604 66,465,558 RGD:6480464
G Pmepa1 prostate transmembrane protein, androgen induced 1 JBrowse link 2 173,224,458 173,276,731 RGD:6480464
G Pnpla6 patatin-like phospholipase domain containing 6 JBrowse link 8 3,515,235 3,544,267 RGD:6480464
G Polr3f polymerase (RNA) III (DNA directed) polypeptide F JBrowse link 2 144,527,745 144,541,779 RGD:6480464
G Pon1 paraoxonase 1 JBrowse link 6 5,168,090 5,193,987 RGD:6480464
G Pparg peroxisome proliferator activated receptor gamma JBrowse link 6 115,360,879 115,490,404 RGD:6480464
G Ppfibp1 PTPRF interacting protein, binding protein 1 (liprin beta 1) JBrowse link 6 146,886,609 147,032,025 RGD:6480464
G Ppig peptidyl-prolyl isomerase G (cyclophilin G) JBrowse link 2 69,722,753 69,754,059 RGD:6480464
G Ppm1d protein phosphatase 1D magnesium-dependent, delta isoform JBrowse link 11 85,311,254 85,347,071 RGD:6480464
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A JBrowse link 7 45,522,917 45,526,268 RGD:6480464
G Ppp4r2 protein phosphatase 4, regulatory subunit 2 JBrowse link 6 100,833,620 100,869,934 RGD:6480464
G Prc1 protein regulator of cytokinesis 1 JBrowse link 7 80,294,445 80,316,259 RGD:6480464
G Prdm1 PR domain containing 1, with ZNF domain JBrowse link 10 44,437,174 44,528,558 RGD:6480464
G Prkab1 protein kinase, AMP-activated, beta 1 non-catalytic subunit JBrowse link 5 116,013,586 116,024,503 RGD:6480464
G Prkab2 protein kinase, AMP-activated, beta 2 non-catalytic subunit JBrowse link 3 97,658,211 97,673,812 RGD:6480464
G Psat1 phosphoserine aminotransferase 1 JBrowse link 19 15,905,123 15,925,059 RGD:6480464
G Pspc1 paraspeckle protein 1 JBrowse link 14 56,722,441 56,778,318 RGD:6480464
G Pten phosphatase and tensin homolog JBrowse link 19 32,757,577 32,826,160 RGD:6480464
G Pycr1 pyrroline-5-carboxylate reductase 1 JBrowse link 11 120,635,712 120,643,769 RGD:6480464
G Rab26 RAB26, member RAS oncogene family JBrowse link 17 24,529,054 24,533,747 RGD:6480464
G Rab31 RAB31, member RAS oncogene family JBrowse link 17 65,651,726 65,772,752 RGD:6480464
G Rara retinoic acid receptor, alpha JBrowse link 11 98,927,800 98,974,942 RGD:6480464
G Rffl ring finger and FYVE like domain containing protein JBrowse link 11 82,803,819 82,871,236 RGD:6480464
G Rit1 Ras-like without CAAX 1 JBrowse link 3 88,716,839 88,731,048 RGD:6480464
G Rnd3 Rho family GTPase 3 JBrowse link 2 51,130,439 51,149,111 RGD:6480464
G Ro60 Ro60, Y RNA binding protein JBrowse link 1 143,750,790 143,777,063 RGD:6480464
G Rrm2b ribonucleotide reductase M2 B (TP53 inducible) JBrowse link 15 37,923,952 37,961,119 RGD:6480464
G Rrp12 ribosomal RNA processing 12 homolog (S. cerevisiae) JBrowse link 19 41,859,483 41,896,153 RGD:6480464
G Rsrc2 arginine/serine-rich coiled-coil 2 JBrowse link 5 123,728,426 123,749,429 RGD:6480464
G Runx1 runt related transcription factor 1 JBrowse link 16 92,601,466 92,826,074 RGD:6480464
G Runx2 runt related transcription factor 2 JBrowse link 17 44,495,987 44,814,797 RGD:6480464
G Scamp1 secretory carrier membrane protein 1 JBrowse link 13 94,201,310 94,285,831 RGD:6480464
G Sectm1a secreted and transmembrane 1A JBrowse link 11 121,067,395 121,097,153 RGD:6480464
G Sertad1 SERTA domain containing 1 JBrowse link 7 27,486,953 27,490,316 RGD:6480464
G Setx senataxin JBrowse link 2 29,123,588 29,182,471 RGD:6480464
G Sfn stratifin JBrowse link 4 133,600,556 133,602,168 RGD:6480464
G Shank3 SH3 and multiple ankyrin repeat domains 3 JBrowse link 15 89,493,013 89,560,261 RGD:6480464
G Siah2 siah E3 ubiquitin protein ligase 2 JBrowse link 3 58,674,949 58,692,439 RGD:6480464
G Sipa1l2 signal-induced proliferation-associated 1 like 2 JBrowse link 8 125,418,068 125,569,863 RGD:6480464
G Siva1 SIVA1, apoptosis-inducing factor JBrowse link 12 112,644,828 112,649,152 RGD:6480464
G Slc12a8 solute carrier family 12 (potassium/chloride transporters), member 8 JBrowse link 16 33,517,328 33,664,138 RGD:6480464
G Slc1a4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 JBrowse link 11 20,302,180 20,332,713 RGD:6480464
G Slc1a5 solute carrier family 1 (neutral amino acid transporter), member 5 JBrowse link 7 16,781,334 16,798,274 RGD:6480464
G Slc25a20 solute carrier family 25 (mitochondrial carnitine/acylcarnitine translocase), member 20 JBrowse link 9 108,662,136 108,684,642 RGD:6480464
G Slc3a2 solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2 JBrowse link 19 8,706,882 8,723,369 RGD:6480464
G Slc6a9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9 JBrowse link 4 117,835,258 117,869,305 RGD:6480464
G Slc7a5 solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 JBrowse link 8 121,881,146 121,907,686 RGD:6480464
G Smap1 small ArfGAP 1 JBrowse link 1 23,844,825 23,922,381 RGD:6480464
G Son Son DNA binding protein JBrowse link 16 91,647,824 91,679,192 RGD:6480464
G Sorl1 sortilin-related receptor, LDLR class A repeats-containing JBrowse link 9 41,964,709 42,124,297 RGD:6480464
G Spry1 sprouty RTK signaling antagonist 1 JBrowse link 3 37,639,291 37,644,599 RGD:6480464
G Srd5a3 steroid 5 alpha-reductase 3 JBrowse link 5 76,140,273 76,155,503 RGD:6480464
G Srxn1 sulfiredoxin 1 homolog (S. cerevisiae) JBrowse link 2 152,105,524 152,111,376 RGD:6480464
G Sulf2 sulfatase 2 JBrowse link 2 166,073,899 166,155,683 RGD:6480464
G Taok1 TAO kinase 1 JBrowse link 11 77,529,162 77,625,359 RGD:6480464
G Tars threonyl-tRNA synthetase JBrowse link 15 11,383,663 11,399,658 RGD:6480464
G Tbxas1 thromboxane A synthase 1, platelet JBrowse link 6 38,864,159 39,084,590 RGD:6480464
G Tfap2a transcription factor AP-2, alpha JBrowse link 13 40,713,802 40,738,238 RGD:6480464
G Tfe3 transcription factor E3 JBrowse link X 7,762,530 7,775,202 RGD:6480464
G Tgfb1 transforming growth factor, beta 1 JBrowse link 7 25,687,002 25,705,077 RGD:6480464
G Tigar Trp53 induced glycolysis regulatory phosphatase JBrowse link 6 127,085,116 127,109,552 RGD:6480464
G Timm17b translocase of inner mitochondrial membrane 17b JBrowse link X 7,899,336 7,907,652 RGD:6480464
G Timp1 tissue inhibitor of metalloproteinase 1 JBrowse link X 20,870,166 20,874,737 RGD:6480464
G Tiparp TCDD-inducible poly(ADP-ribose) polymerase JBrowse link 3 65,528,447 65,555,518 RGD:6480464
G Tmem45b transmembrane protein 45b JBrowse link 9 31,426,196 31,464,238 RGD:6480464
G Tmem94 transmembrane protein 94 JBrowse link 11 115,765,419 115,799,033 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 17 35,199,367 35,202,007 RGD:6480464
G Tnfaip8 tumor necrosis factor, alpha-induced protein 8 JBrowse link 18 49,979,427 50,093,229 RGD:6480464
G Tpcn1 two pore channel 1 JBrowse link 5 120,534,157 120,588,678 RGD:6480464
G Tpd52l1 tumor protein D52-like 1 JBrowse link 10 31,332,373 31,445,987 RGD:6480464
G Trafd1 TRAF type zinc finger domain containing 1 JBrowse link 5 121,371,725 121,386,570 RGD:6480464
G Trp53 transformation related protein 53 JBrowse link 11 69,580,348 69,591,873 RGD:6480464
G Trp53inp1 transformation related protein 53 inducible nuclear protein 1 JBrowse link 4 11,156,441 11,174,379 RGD:6480464
G Tspan12 tetraspanin 12 JBrowse link 6 21,771,391 21,879,596 RGD:6480464
G Txn1 thioredoxin 1 JBrowse link 4 57,943,373 57,956,411 RGD:6480464
G Txnrd1 thioredoxin reductase 1 JBrowse link 10 82,833,951 82,897,724 RGD:6480464
G Ube2g2 ubiquitin-conjugating enzyme E2G 2 JBrowse link 10 77,622,321 77,645,990 RGD:6480464
G Ube2o ubiquitin-conjugating enzyme E2O JBrowse link 11 116,537,740 116,581,503 RGD:6480464
G Unkl unkempt family like zinc finger JBrowse link 17 25,188,361 25,234,443 RGD:6480464
G Vars valyl-tRNA synthetase JBrowse link 17 35,000,907 35,016,329 RGD:6480464
G Vegfb vascular endothelial growth factor B JBrowse link 19 6,982,472 6,987,651 RGD:6480464
G Vim vimentin JBrowse link 2 13,574,311 13,582,826 RGD:6480464
G Vtcn1 V-set domain containing T cell activation inhibitor 1 JBrowse link 3 100,825,459 100,896,922 RGD:6480464
G Wars tryptophanyl-tRNA synthetase JBrowse link 12 108,860,030 108,894,175 RGD:6480464
G Wdr63 WD repeat domain 63 JBrowse link 3 146,040,526 146,108,100 RGD:6480464
G Wwc2 WW, C2 and coiled-coil domain containing 2 JBrowse link 8 47,826,082 47,990,544 RGD:6480464
G Xbp1 X-box binding protein 1 JBrowse link 11 5,520,641 5,525,993 RGD:6480464
G Yars tyrosyl-tRNA synthetase JBrowse link 4 129,189,734 129,219,240 RGD:6480464
G Yeats2 YEATS domain containing 2 JBrowse link 16 20,141,053 20,232,573 RGD:6480464
G Ythdc2 YTH domain containing 2 JBrowse link 18 44,827,730 44,889,720 RGD:6480464
G Zfp266 zinc finger protein 266 JBrowse link 9 20,495,068 20,521,419 RGD:6480464
G Zfx zinc finger protein X-linked JBrowse link X 94,074,631 94,150,645 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20971
    role 20952
      application 20373
        pharmaceutical 19971
          drug 19971
            antineoplastic agent 17297
              clodronic acid 240
Path 2
Term Annotations click to browse term
  CHEBI ontology 20971
    subatomic particle 20965
      composite particle 20965
        hadron 20965
          baryon 20965
            nucleon 20965
              atomic nucleus 20965
                atom 20965
                  main group element atom 20803
                    p-block element atom 20803
                      carbon group element atom 20543
                        carbon group molecular entity 20543
                          organic molecular entity 20519
                            heteroorganic entity 20159
                              organohalogen compound 18129
                                organochlorine compound 17851
                                  clodronic acid 240
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.