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ONTOLOGY REPORT - ANNOTATIONS


Term:1-(3-chlorophenyl)piperazine
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Accession:CHEBI:10588 term browser browse the term
Definition:A N-arylpiperazine that is piperazine carrying a 3-chlorophenyl substituent at position 1. It is a metabolite of the antidepressant drug trazodone.
Synonyms:related_synonym: (m-CPP);   Formula=C10H13ClN2;   InChI=1S/C10H13ClN2/c11-9-2-1-3-10(8-9)13-6-4-12-5-7-13/h1-3,8,12H,4-7H2;   InChIKey=VHFVKMTVMIZMIK-UHFFFAOYSA-N;   SMILES=Clc1cccc(c1)N1CCNCC1;   m-Chlorophenylpiperazine
 xref: Beilstein:8409;   CAS:6640-24-0;   HMDB:HMDB0061008;   KEGG:C11738;   LINCS:LSM-25627
 xref_mesh: MESH:C015068
 xref: PMID:11311791;   PMID:18621591;   PMID:23768699;   PMID:24062697;   PMID:6827905;   Reaxys:8409;   Wikipedia:Meta-Chlorophenylpiperazine


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1-(3-chlorophenyl)piperazine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 JBrowse link 7 123,599,264 123,608,436 RGD:6480464
G Fos Fos proto-oncogene, AP-1 transcription factor subunit JBrowse link 6 109,300,433 109,303,299 RGD:6480464
G Gabbr2 gamma-aminobutyric acid type B receptor subunit 2 JBrowse link 5 62,276,100 62,621,737 RGD:6480464
G Gabra1 gamma-aminobutyric acid type A receptor subunit alpha 1 JBrowse link 10 27,310,718 27,371,802 RGD:6480464
G Gabrb2 gamma-aminobutyric acid type A receptor subunit beta 2 JBrowse link 10 27,973,694 28,193,072 RGD:6480464
G Gabrg2 gamma-aminobutyric acid type A receptor subunit gamma 2 JBrowse link 10 27,090,913 27,179,786 RGD:6480464
G Htr1a 5-hydroxytryptamine receptor 1A JBrowse link 2 36,246,628 36,247,896 RGD:6480464
G Htr2a 5-hydroxytryptamine receptor 2A JBrowse link 15 56,666,152 56,732,469 RGD:6480464
G Htr2c 5-hydroxytryptamine receptor 2C JBrowse link X 118,084,520 118,318,040 RGD:6480464
G Lep leptin JBrowse link 4 56,337,695 56,351,818 RGD:6480464
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 JBrowse link 11 65,022,100 65,058,546 RGD:6480464
G Plcb1 phospholipase C beta 1 JBrowse link 3 127,721,244 128,419,565 RGD:6480464
G Prl prolactin JBrowse link 17 39,814,236 39,824,299 RGD:6480464
G Slc6a4 solute carrier family 6 member 4 JBrowse link 10 63,153,656 63,188,377 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19790
    role 19738
      biological role 19737
        xenobiotic 18412
          1-(3-chlorophenyl)piperazine 14
Path 2
Term Annotations click to browse term
  CHEBI ontology 19790
    subatomic particle 19788
      composite particle 19788
        hadron 19788
          baryon 19788
            nucleon 19788
              atomic nucleus 19788
                atom 19788
                  main group element atom 19674
                    main group molecular entity 19674
                      s-block molecular entity 19416
                        hydrogen molecular entity 19407
                          hydrides 18389
                            inorganic hydride 17221
                              pnictogen hydride 17184
                                nitrogen hydride 17018
                                  azane 16713
                                    ammonia 16712
                                      organic amino compound 16711
                                        tertiary amino compound 8631
                                          N-arylpiperazine 2709
                                            1-(3-chlorophenyl)piperazine 14
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.