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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:gamma-terpinene
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Accession:CHEBI:10577 term browser browse the term
Definition:One of three isomeric monoterpenes differing in the positions of their two double bonds (alpha- and beta-terpinene being the others). In gamma-terpinene the double bonds are at the 1- and 4-positions of the p-menthane skeleton.
Synonyms:related_synonym: 1,4-p-Menthadiene;   1-Isopropyl-4-methylcyclohexa-1,4-diene;   1-Methyl-4-(1-methylethyl)-1,4-cyclohexadiene;   1-methyl-4-propan-2-yl-cyclohexa-1,4-diene;   1-methyl-4-propan-2-ylcyclohexa-1,4-diene;   4-Isopropyl-1-methyl-1,4-cyclohexadiene;   Crithmene;   Formula=C10H16;   InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,7-8H,5-6H2,1-3H3;   InChIKey=YKFLAYDHMOASIY-UHFFFAOYSA-N;   Moslene;   SMILES=CC(C)C1=CCC(C)=CC1;   p-Mentha-1,4-diene
 xref: BPDB:2013;   CAS:99-85-4;   HMDB:HMDB0005806;   KEGG:C09900;   KNApSAcK:C00003061;   LIPID_MAPS_instance:LMPR0102090027
 xref_mesh: MESH:C018669
 xref: MetaCyc:CPD-8736;   PMID:12696969;   PMID:17314143;   PMID:22284503;   PMID:24066512;   PMID:24421258;   Reaxys:2038347;   Wikipedia:Terpinene


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gamma-terpinene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP-binding cassette, sub-family B member 1A multiple interactions ISO gamma-terpinene inhibits the reaction [ABCB1 protein results in increased uptake of Digoxin] CTD PMID:16904803 NCBI chr 5:8,617,091...8,798,575
Ensembl chr 5:8,710,077...8,798,575 		JBrowse link
G Ahr aryl-hydrocarbon receptor multiple interactions ISO [4-cymene co-treated with beta-pinene co-treated with gamma-terpinene co-treated with cuminol] results in increased activity of AHR protein; [4-cymene co-treated with gamma-terpinene co-treated with Thymol co-treated with carvacrol] inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of AHR protein]; [4-cymene co-treated with gamma-terpinene co-treated with Thymol co-treated with carvacrol] results in increased activity of AHR protein; [4-cymene co-treated with gamma-terpinene co-treated with Thymol] inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of AHR protein]; [4-cymene co-treated with gamma-terpinene co-treated with Thymol] results in increased activity of AHR protein CTD PMID:29191726 NCBI chr12:35,547,978...35,584,988
Ensembl chr12:35,547,973...35,585,037 		JBrowse link
G Ar androgen receptor multiple interactions ISO gamma-terpinene inhibits the reaction [Testosterone results in increased activity of AR protein] CTD PMID:31393563 NCBI chr  X:97,192,363...97,366,824
Ensembl chr  X:97,192,375...97,366,821 		JBrowse link
G Ctsd cathepsin D increases expression ISO gamma-terpinene results in increased expression of CTSD mRNA CTD PMID:31393563 NCBI chr 7:141,929,647...141,941,564
Ensembl chr 7:141,929,648...141,941,775 		JBrowse link
G Cyp4f16 cytochrome P450, family 4, subfamily f, polypeptide 16 multiple interactions ISO gamma-terpinene inhibits the reaction [Testosterone results in increased expression of CYP4F8 mRNA] CTD PMID:31393563 NCBI chr17:32,755,517...32,770,772
Ensembl chr17:32,755,532...32,770,772 		JBrowse link
G Greb1 gene regulated by estrogen in breast cancer protein increases expression ISO gamma-terpinene results in increased expression of GREB1 mRNA CTD PMID:31393563 NCBI chr12:16,720,616...16,851,395
Ensembl chr12:16,720,616...16,850,887 		JBrowse link
G Pgr progesterone receptor increases expression
multiple interactions		 ISO gamma-terpinene results in increased expression of PGR mRNA
Fulvestrant inhibits the reaction [gamma-terpinene results in increased expression of PGR mRNA]		 CTD PMID:31393563 NCBI chr 9:8,890,017...8,968,612
Ensembl chr 9:8,899,834...8,968,612 		JBrowse link
G Sec14l2 SEC14-like lipid binding 2 multiple interactions ISO gamma-terpinene inhibits the reaction [Testosterone results in increased expression of SEC14L2 mRNA] CTD PMID:31393563 NCBI chr11:4,047,039...4,068,729
Ensembl chr11:4,047,039...4,073,415 		JBrowse link
tea tree oil term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor multiple interactions ISO Tea Tree Oil inhibits the reaction [Testosterone results in increased activity of AR protein] CTD PMID:31393563 NCBI chr  X:97,192,363...97,366,824
Ensembl chr  X:97,192,375...97,366,821 		JBrowse link
G Ctsd cathepsin D multiple interactions
increases expression		 ISO Fulvestrant inhibits the reaction [Tea Tree Oil results in increased expression of CTSD mRNA] CTD PMID:31393563 NCBI chr 7:141,929,647...141,941,564
Ensembl chr 7:141,929,648...141,941,775 		JBrowse link
G Cyp4f16 cytochrome P450, family 4, subfamily f, polypeptide 16 multiple interactions ISO Tea Tree Oil inhibits the reaction [Testosterone results in increased expression of CYP4F8 mRNA] CTD PMID:31393563 NCBI chr17:32,755,517...32,770,772
Ensembl chr17:32,755,532...32,770,772 		JBrowse link
G Esr1 estrogen receptor 1 (alpha) increases activity ISO Tea Tree Oil results in increased activity of ESR1 protein CTD PMID:31393563 NCBI chr10:4,561,989...4,955,633
Ensembl chr10:4,561,593...4,955,614 		JBrowse link
G Greb1 gene regulated by estrogen in breast cancer protein multiple interactions
increases expression		 ISO Fulvestrant inhibits the reaction [Tea Tree Oil results in increased expression of GREB1 mRNA] CTD PMID:31393563 NCBI chr12:16,720,616...16,851,395
Ensembl chr12:16,720,616...16,850,887 		JBrowse link
G Pgr progesterone receptor multiple interactions
increases expression		 ISO Fulvestrant inhibits the reaction [Tea Tree Oil results in increased expression of PGR mRNA] CTD PMID:31393563 NCBI chr 9:8,890,017...8,968,612
Ensembl chr 9:8,899,834...8,968,612 		JBrowse link
G Sec14l2 SEC14-like lipid binding 2 multiple interactions ISO Tea Tree Oil inhibits the reaction [Testosterone results in increased expression of SEC14L2 mRNA] CTD PMID:31393563 NCBI chr11:4,047,039...4,068,729
Ensembl chr11:4,047,039...4,073,415 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 22178
    role 22194
      chemical role 21407
        antioxidant 16394
          gamma-terpinene 9
            tea tree oil 7
Path 2
Term Annotations click to browse term
  CHEBI ontology 22178
    subatomic particle 22170
      composite particle 22170
        hadron 22201
          baryon 22170
            nucleon 22170
              atomic nucleus 22170
                atom 22170
                  main group element atom 22104
                    main group molecular entity 22104
                      s-block molecular entity 21729
                        hydrogen molecular entity 21646
                          hydrides 20758
                            organic hydride 20308
                              organic fundamental parent 20308
                                hydrocarbon 19888
                                  olefin 8961
                                    cyclic olefin 415
                                      monocyclic olefin 412
                                        cycloalkadiene 327
                                          cyclohexadiene 326
                                            gamma-terpinene 9
                                              tea tree oil 7
paths to the root