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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:gamma-terpinene
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Accession:CHEBI:10577 term browser browse the term
Definition:One of three isomeric monoterpenes differing in the positions of their two double bonds (alpha- and beta-terpinene being the others). In gamma-terpinene the double bonds are at the 1- and 4-positions of the p-menthane skeleton.
Synonyms:related_synonym: 1,4-p-Menthadiene;   1-Isopropyl-4-methylcyclohexa-1,4-diene;   1-Methyl-4-(1-methylethyl)-1,4-cyclohexadiene;   1-methyl-4-propan-2-yl-cyclohexa-1,4-diene;   1-methyl-4-propan-2-ylcyclohexa-1,4-diene;   4-Isopropyl-1-methyl-1,4-cyclohexadiene;   Crithmene;   Formula=C10H16;   InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,7-8H,5-6H2,1-3H3;   InChIKey=YKFLAYDHMOASIY-UHFFFAOYSA-N;   Moslene;   SMILES=CC(C)C1=CCC(C)=CC1;   p-Mentha-1,4-diene
 xref: BPDB:2013;   CAS:99-85-4;   HMDB:HMDB0005806;   KEGG:C09900;   KNApSAcK:C00003061;   LIPID_MAPS_instance:LMPR0102090027
 xref_mesh: MESH:C018669
 xref: MetaCyc:CPD-8736;   PMID:12696969;   PMID:17314143;   PMID:22284503;   PMID:24066512;   PMID:24421258;   Reaxys:2038347;   Wikipedia:Terpinene


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gamma-terpinene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions ISO gamma-terpinene inhibits the reaction [ABCB1 protein results in increased uptake of Digoxin] CTD PMID:16904803 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions ISO [4-cymene co-treated with beta-pinene co-treated with gamma-terpinene co-treated with cuminol] results in increased activity of AHR protein; [4-cymene co-treated with gamma-terpinene co-treated with Thymol co-treated with carvacrol] inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of AHR protein]; [4-cymene co-treated with gamma-terpinene co-treated with Thymol co-treated with carvacrol] results in increased activity of AHR protein; [4-cymene co-treated with gamma-terpinene co-treated with Thymol] inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of AHR protein]; [4-cymene co-treated with gamma-terpinene co-treated with Thymol] results in increased activity of AHR protein CTD PMID:29191726 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Ar androgen receptor multiple interactions ISO gamma-terpinene inhibits the reaction [Testosterone results in increased activity of AR protein] CTD PMID:31393563 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Ctsd cathepsin D increases expression ISO gamma-terpinene results in increased expression of CTSD mRNA CTD PMID:31393563 NCBI chr 1:215,541,570...215,553,446
Ensembl chr 1:215,541,542...215,553,451
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 decreases activity EXP gamma-terpinene results in decreased activity of CYP2B1 protein CTD PMID:9242356 NCBI chr 7:99,142,431...99,183,540
Ensembl chr 7:99,142,450...99,181,783
JBrowse link
G Greb1 growth regulating estrogen receptor binding 1 increases expression ISO gamma-terpinene results in increased expression of GREB1 mRNA CTD PMID:31393563 NCBI chr 6:41,932,941...42,002,770
Ensembl chr 6:41,932,244...42,002,819
JBrowse link
G Pgr progesterone receptor multiple interactions
increases expression
ISO Fulvestrant inhibits the reaction [gamma-terpinene results in increased expression of PGR mRNA] CTD PMID:31393563 NCBI chr 8:7,128,656...7,187,796
Ensembl chr 8:7,128,656...7,187,796
JBrowse link
G Sec14l2 SEC14-like lipid binding 2 multiple interactions ISO gamma-terpinene inhibits the reaction [Testosterone results in increased expression of SEC14L2 mRNA] CTD PMID:31393563 NCBI chr14:84,335,594...84,360,354
Ensembl chr14:84,335,597...84,355,528
JBrowse link
tea tree oil term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor multiple interactions ISO Tea Tree Oil inhibits the reaction [Testosterone results in increased activity of AR protein] CTD PMID:31393563 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Ctsd cathepsin D multiple interactions
increases expression
ISO Fulvestrant inhibits the reaction [Tea Tree Oil results in increased expression of CTSD mRNA] CTD PMID:31393563 NCBI chr 1:215,541,570...215,553,446
Ensembl chr 1:215,541,542...215,553,451
JBrowse link
G Esr1 estrogen receptor 1 increases activity ISO Tea Tree Oil results in increased activity of ESR1 protein CTD PMID:31393563 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Greb1 growth regulating estrogen receptor binding 1 multiple interactions
increases expression
ISO Fulvestrant inhibits the reaction [Tea Tree Oil results in increased expression of GREB1 mRNA] CTD PMID:31393563 NCBI chr 6:41,932,941...42,002,770
Ensembl chr 6:41,932,244...42,002,819
JBrowse link
G Pgr progesterone receptor increases expression
multiple interactions
ISO Tea Tree Oil results in increased expression of PGR mRNA
Fulvestrant inhibits the reaction [Tea Tree Oil results in increased expression of PGR mRNA]
CTD PMID:31393563 NCBI chr 8:7,128,656...7,187,796
Ensembl chr 8:7,128,656...7,187,796
JBrowse link
G RGD1559459 similar to Expressed sequence AI788959 multiple interactions ISO Tea Tree Oil inhibits the reaction [Testosterone results in increased expression of UGT2B28 mRNA] CTD PMID:31393563 NCBI chr14:22,932,454...22,955,663
Ensembl chr14:22,937,421...22,952,822
JBrowse link
G Sec14l2 SEC14-like lipid binding 2 multiple interactions ISO Tea Tree Oil inhibits the reaction [Testosterone results in increased expression of SEC14L2 mRNA] CTD PMID:31393563 NCBI chr14:84,335,594...84,360,354
Ensembl chr14:84,335,597...84,355,528
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19785
    role 19732
      chemical role 19248
        antioxidant 14209
          gamma-terpinene 10
            tea tree oil 7
Path 2
Term Annotations click to browse term
  CHEBI ontology 19785
    subatomic particle 19782
      composite particle 19782
        hadron 19782
          baryon 19782
            nucleon 19782
              atomic nucleus 19782
                atom 19782
                  main group element atom 19670
                    main group molecular entity 19670
                      s-block molecular entity 19428
                        hydrogen molecular entity 19418
                          hydrides 18685
                            organic hydride 18248
                              organic fundamental parent 18248
                                hydrocarbon 17968
                                  olefin 7183
                                    cyclic olefin 105
                                      monocyclic olefin 102
                                        cycloalkadiene 10
                                          cyclohexadiene 10
                                            gamma-terpinene 10
                                              tea tree oil 7
paths to the root

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