CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: gamma-terpinene
Accession: CHEBI:10577
browse the term
Definition: One of three isomeric monoterpenes differing in the positions of their two double bonds (alpha- and beta-terpinene being the others). In gamma-terpinene the double bonds are at the 1- and 4-positions of the p-menthane skeleton.
Synonyms: related_synonym: 1,4-p-Menthadiene; 1-Isopropyl-4-methylcyclohexa-1,4-diene; 1-Methyl-4-(1-methylethyl)-1,4-cyclohexadiene; 1-methyl-4-propan-2-yl-cyclohexa-1,4-diene; 1-methyl-4-propan-2-ylcyclohexa-1,4-diene; 4-Isopropyl-1-methyl-1,4-cyclohexadiene; Crithmene; Formula=C10H16; InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,7-8H,5-6H2,1-3H3; InChIKey=YKFLAYDHMOASIY-UHFFFAOYSA-N; Moslene; SMILES=CC(C)C1=CCC(C)=CC1; p-Mentha-1,4-diene
xref: BPDB:2013; CAS:99-85-4; HMDB:HMDB0005806; KEGG:C09900; KNApSAcK:C00003061; LIPID_MAPS_instance:LMPR0102090027
xref_mesh: MESH:C018669
xref: MetaCyc:CPD-8736; PMID:12696969; PMID:17314143; PMID:22284503; PMID:24066512; PMID:24421258; Reaxys:2038347; Wikipedia:Terpinene
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Abcb1a
ATP binding cassette subfamily B member 1A
multiple interactions
ISO
gamma-terpinene inhibits the reaction [ABCB1 protein results in increased uptake of Digoxin]
CTD
PMID:16904803
NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
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Ahr
aryl hydrocarbon receptor
multiple interactions
ISO
[4-cymene co-treated with beta-pinene co-treated with gamma-terpinene co-treated with cuminol] results in increased activity of AHR protein; [4-cymene co-treated with gamma-terpinene co-treated with Thymol co-treated with carvacrol] inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of AHR protein]; [4-cymene co-treated with gamma-terpinene co-treated with Thymol co-treated with carvacrol] results in increased activity of AHR protein; [4-cymene co-treated with gamma-terpinene co-treated with Thymol] inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of AHR protein]; [4-cymene co-treated with gamma-terpinene co-treated with Thymol] results in increased activity of AHR protein
CTD
PMID:29191726
NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
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Ar
androgen receptor
multiple interactions
ISO
gamma-terpinene inhibits the reaction [Testosterone results in increased activity of AR protein]
CTD
PMID:31393563
NCBI chr X:63,104,771...63,273,934
Ensembl chr X:63,104,771...63,273,925
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Ctsd
cathepsin D
increases expression
ISO
gamma-terpinene results in increased expression of CTSD mRNA
CTD
PMID:31393563
NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488
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Cyp2b1
cytochrome P450, family 2, subfamily b, polypeptide 1
decreases activity
EXP
gamma-terpinene results in decreased activity of CYP2B1 protein
CTD
PMID:9242356
NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052
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Cyp4f6
cytochrome P450, family 4, subfamily f, polypeptide 6
multiple interactions
ISO
gamma-terpinene inhibits the reaction [Testosterone results in increased expression of CYP4F8 mRNA]
CTD
PMID:31393563
NCBI chr 7:12,030,276...12,058,020
Ensembl chr 7:12,030,301...12,057,782
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Greb1
growth regulating estrogen receptor binding 1
increases expression
ISO
gamma-terpinene results in increased expression of GREB1 mRNA
CTD
PMID:31393563
NCBI chr 6:39,440,522...39,562,364
Ensembl chr 6:39,440,504...39,581,633
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Pgr
progesterone receptor
multiple interactions increases expression
ISO
Fulvestrant inhibits the reaction [gamma-terpinene results in increased expression of PGR mRNA]
CTD
PMID:31393563
NCBI chr 8:6,072,673...6,131,552
Ensembl chr 8:6,072,673...6,131,344
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Sec14l2
SEC14-like lipid binding 2
multiple interactions
ISO
gamma-terpinene inhibits the reaction [Testosterone results in increased expression of SEC14L2 mRNA]
CTD
PMID:31393563
NCBI chr14:78,973,805...78,998,480
Ensembl chr14:78,973,808...78,993,788
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Ar
androgen receptor
multiple interactions
ISO
Tea Tree Oil inhibits the reaction [Testosterone results in increased activity of AR protein]
CTD
PMID:31393563
NCBI chr X:63,104,771...63,273,934
Ensembl chr X:63,104,771...63,273,925
G
Ctsd
cathepsin D
multiple interactions increases expression
ISO
Fulvestrant inhibits the reaction [Tea Tree Oil results in increased expression of CTSD mRNA]
CTD
PMID:31393563
NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488
G
Cyp4f6
cytochrome P450, family 4, subfamily f, polypeptide 6
multiple interactions
ISO
Tea Tree Oil inhibits the reaction [Testosterone results in increased expression of CYP4F8 mRNA]
CTD
PMID:31393563
NCBI chr 7:12,030,276...12,058,020
Ensembl chr 7:12,030,301...12,057,782
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Esr1
estrogen receptor 1
increases activity
ISO
Tea Tree Oil results in increased activity of ESR1 protein
CTD
PMID:31393563
NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
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Greb1
growth regulating estrogen receptor binding 1
multiple interactions increases expression
ISO
Fulvestrant inhibits the reaction [Tea Tree Oil results in increased expression of GREB1 mRNA]
CTD
PMID:31393563
NCBI chr 6:39,440,522...39,562,364
Ensembl chr 6:39,440,504...39,581,633
G
Pgr
progesterone receptor
increases expression multiple interactions
ISO
Tea Tree Oil results in increased expression of PGR mRNA Fulvestrant inhibits the reaction [Tea Tree Oil results in increased expression of PGR mRNA]
CTD
PMID:31393563
NCBI chr 8:6,072,673...6,131,552
Ensembl chr 8:6,072,673...6,131,344
G
Sec14l2
SEC14-like lipid binding 2
multiple interactions
ISO
Tea Tree Oil inhibits the reaction [Testosterone results in increased expression of SEC14L2 mRNA]
CTD
PMID:31393563
NCBI chr14:78,973,805...78,998,480
Ensembl chr14:78,973,808...78,993,788
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Ugt2b34l1
UDP glucuronosyltransferase 2 family, polypeptide B34 like 1
multiple interactions
ISO
Tea Tree Oil inhibits the reaction [Testosterone results in increased expression of UGT2B28 mRNA]
CTD
PMID:31393563
NCBI chr14:21,146,140...21,167,706
Ensembl chr14:21,145,827...21,167,704
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