Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:sulfamerazine
go back to main search page
Accession:CHEBI:102130 term browser browse the term
Definition:A sulfonamide consisting of pyrimidine with a methyl substituent at the 4-position and a 4-aminobenzenesulfonamido group at the 2-position.
Synonyms:exact_synonym: 4-amino-N-(4-methylpyrimidin-2-yl)benzenesulfonamide
 related_synonym: (p-Aminobenzolsulfonyl)-2-amino-4-methylpyrimidin;   2-(4-Aminobenzenesulfonamido)-4-methylpyrimidine;   2-(Sulfanilamido)-4-methylpyrimidine;   2-(p-Aminobenzolsulfonamido)-4-methylpyrimidine;   2-Sulfa-4-methylpyrimidine;   4-Amino-N-(4-methyl-2-pyrimidinyl)-benzenesulfonamide;   Formula=C11H12N4O2S;   InChI=1S/C11H12N4O2S/c1-8-6-7-13-11(14-8)15-18(16,17)10-4-2-9(12)3-5-10/h2-7H,12H2,1H3,(H,13,14,15);   InChIKey=QPPBRPIAZZHUNT-UHFFFAOYSA-N;   N(1)-(4-Methyl-2-pyrimidinyl)sulfanilamide;   N-(4-Methyl-2-pyrimidyl)sulfanilamide;   SMILES=Cc1ccnc(NS(=O)(=O)c2ccc(N)cc2)n1;   Sulfamethyldiazine;   Sulphamerazine;   sulfamerazina;   sulfamerazinum
 xref: Beilstein:249133;   CAS:127-79-7;   DrugBank:DB01581;   Drug_Central:2510;   Gmelin:219949;   KEGG:D02435;   LINCS:LSM-5979
 xref_mesh: MESH:D013416
 xref: PMID:11431418;   PMID:13037579;   PMID:23627444;   PMID:2434548;   PMID:24508883;   PMID:6864729;   Patent:US2407966;   Wikipedia:Sulfamerazine


show annotations for term's descendants           Sort by:
sulfamerazine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hmbs hydroxymethylbilane synthase decreases activity
increases activity		 ISO Sulfamerazine decreases activity of purified Hmbs protein
Sulfamerazine increases activity of purified Hmbs protein		 RGD PMID:6893114 PMID:3702597 RGD:26923963, RGD:4144820 NCBI chr 9:44,247,645...44,255,525
Ensembl chr 9:44,247,636...44,255,525 		JBrowse link
G Slc47a1 solute carrier family 47, member 1 multiple interactions ISO Sulfamerazine affects the reaction [SLC47A1 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:22419765 NCBI chr11:61,234,226...61,269,668
Ensembl chr11:61,234,227...61,269,171 		JBrowse link
G Slc47a2 solute carrier family 47, member 2 multiple interactions ISO Sulfamerazine affects the reaction [SLC47A2 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:22419765 NCBI chr11:61,192,453...61,233,686
Ensembl chr11:61,192,457...61,233,686 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 22194
    role 22179
      biological role 22178
        antimicrobial agent 19567
          sulfonamide antibiotic 2897
            sulfamerazine 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 22194
    subatomic particle 22186
      composite particle 22186
        hadron 22186
          baryon 22186
            nucleon 22186
              atomic nucleus 22186
                atom 22186
                  main group element atom 22120
                    main group molecular entity 22120
                      s-block molecular entity 21717
                        hydrogen molecular entity 21634
                          hydrides 20777
                            inorganic hydride 18692
                              pnictogen hydride 18672
                                nitrogen hydride 18540
                                  azane 18447
                                    ammonia 18446
                                      organic amino compound 18446
                                        aromatic amine 15737
                                          anilines 14580
                                            substituted aniline 14212
                                              sulfanilamide 2892
                                                sulfamerazine 3
paths to the root