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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:sulfamerazine
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Accession:CHEBI:102130 term browser browse the term
Definition:A sulfonamide consisting of pyrimidine with a methyl substituent at the 4-position and a 4-aminobenzenesulfonamido group at the 2-position.
Synonyms:exact_synonym: 4-amino-N-(4-methylpyrimidin-2-yl)benzenesulfonamide
 related_synonym: (p-Aminobenzolsulfonyl)-2-amino-4-methylpyrimidin;   2-(4-Aminobenzenesulfonamido)-4-methylpyrimidine;   2-(Sulfanilamido)-4-methylpyrimidine;   2-(p-Aminobenzolsulfonamido)-4-methylpyrimidine;   2-Sulfa-4-methylpyrimidine;   4-Amino-N-(4-methyl-2-pyrimidinyl)-benzenesulfonamide;   Formula=C11H12N4O2S;   InChI=1S/C11H12N4O2S/c1-8-6-7-13-11(14-8)15-18(16,17)10-4-2-9(12)3-5-10/h2-7H,12H2,1H3,(H,13,14,15);   InChIKey=QPPBRPIAZZHUNT-UHFFFAOYSA-N;   N(1)-(4-Methyl-2-pyrimidinyl)sulfanilamide;   N-(4-Methyl-2-pyrimidyl)sulfanilamide;   SMILES=Cc1ccnc(NS(=O)(=O)c2ccc(N)cc2)n1;   Sulfamethyldiazine;   Sulphamerazine;   sulfamerazina;   sulfamerazinum
 xref: Beilstein:249133;   CAS:127-79-7;   DrugBank:DB01581;   Drug_Central:2510;   Gmelin:219949;   KEGG:D02435;   LINCS:LSM-5979
 xref_mesh: MESH:D013416
 xref: PMID:11431418;   PMID:13037579;   PMID:23627444;   PMID:2434548;   PMID:24508883;   PMID:6864729;   Patent:US2407966;   Wikipedia:Sulfamerazine


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sulfamerazine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G R Hmbs hydroxymethylbilane synthase decreases activity
increases activity
EXP Sulfamerazine decreases activity of purified Hmbs protein
Sulfamerazine increases activity of purified Hmbs protein
RGD PMID:6893114 PMID:3702597 RGD:26923963, RGD:4144820 NCBI chr 8:44,673,554...44,680,950
Ensembl chr 8:44,673,554...44,680,957
JBrowse link
G M Hmbs hydroxymethylbilane synthase decreases activity
increases activity
ISO Sulfamerazine decreases activity of purified Hmbs protein
Sulfamerazine increases activity of purified Hmbs protein
RGD PMID:6893114 PMID:3702597 RGD:26923963, RGD:4144820 NCBI chr 9:44,247,645...44,255,525
Ensembl chr 9:44,247,636...44,255,525
JBrowse link
G H HMBS hydroxymethylbilane synthase decreases activity
increases activity
ISO Sulfamerazine decreases activity of purified Hmbs protein
Sulfamerazine increases activity of purified Hmbs protein
RGD PMID:6893114 PMID:3702597 RGD:26923963, RGD:4144820 NCBI chr11:119,084,881...119,093,549
Ensembl chr11:119,084,866...119,093,834
JBrowse link
G R Slc47a1 solute carrier family 47 member 1 multiple interactions ISO Sulfamerazine affects the reaction [SLC47A1 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:22419765 NCBI chr10:46,034,115...46,088,617
Ensembl chr10:46,034,122...46,087,637
JBrowse link
G M Slc47a1 solute carrier family 47, member 1 multiple interactions ISO Sulfamerazine affects the reaction [SLC47A1 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:22419765 NCBI chr11:61,234,226...61,269,668
Ensembl chr11:61,234,227...61,269,171
JBrowse link
G H SLC47A1 solute carrier family 47 member 1 multiple interactions EXP Sulfamerazine affects the reaction [SLC47A1 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:22419765 NCBI chr17:19,533,854...19,579,034
Ensembl chr17:19,495,385...19,579,034
JBrowse link
G R Slc47a2 solute carrier family 47 member 2 multiple interactions ISO Sulfamerazine affects the reaction [SLC47A2 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:22419765 NCBI chr10:45,990,806...46,033,937
Ensembl chr10:45,991,095...46,033,904
JBrowse link
G M Slc47a2 solute carrier family 47, member 2 multiple interactions ISO Sulfamerazine affects the reaction [SLC47A2 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:22419765 NCBI chr11:61,192,453...61,233,686
Ensembl chr11:61,192,457...61,233,686
JBrowse link
G H SLC47A2 solute carrier family 47 member 2 multiple interactions EXP Sulfamerazine affects the reaction [SLC47A2 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:22419765 NCBI chr17:19,678,317...19,718,979
Ensembl chr17:19,678,288...19,718,979
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 73050
    role 72883
      biological role 72856
        antimicrobial agent 59000
          sulfonamide antibiotic 823
            sulfamerazine 9
Path 2
Term Annotations click to browse term
  CHEBI ontology 73050
    subatomic particle 73003
      composite particle 73003
        hadron 73003
          baryon 73003
            nucleon 73003
              atomic nucleus 73003
                atom 73003
                  main group element atom 72655
                    main group molecular entity 72654
                      s-block molecular entity 71286
                        hydrogen molecular entity 70807
                          hydrides 67375
                            inorganic hydride 57422
                              pnictogen hydride 57318
                                nitrogen hydride 56851
                                  azane 56242
                                    ammonia 56239
                                      organic amino compound 56130
                                        aromatic amine 46196
                                          anilines 42782
                                            substituted aniline 41714
                                              sulfanilamide 809
                                                sulfamerazine 9
paths to the root