Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:ethoxzolamide
go back to main search page
Accession:CHEBI:101096 term browser browse the term
Definition:A sulfonamide that is 1,3-benzothiazole-2-sulfonamide which is substituted by an ethoxy group at position 6. A carbonic anhydrase inhibitor, it has been used in the treatment of glaucoma, and as a diuretic.
Synonyms:exact_synonym: 6-ethoxy-1,3-benzothiazole-2-sulfonamide
 related_synonym: 6-Ethoxy-benzothiazole-2-sulfonic acid amide;   6-ethoxy-2-benzothiazolesulfonamide;   6-ethoxybenzothiazole-2-sulfonamide;   Formula=C9H10N2O3S2;   InChI=1S/C9H10N2O3S2/c1-2-14-6-3-4-7-8(5-6)15-9(11-7)16(10,12)13/h3-5H,2H2,1H3,(H2,10,12,13);   InChIKey=OUZWUKMCLIBBOG-UHFFFAOYSA-N;   SMILES=CCOc1ccc2nc(sc2c1)S(N)(=O)=O;   ethoxazolamide;   ethoxyzolamide
 xref: CAS:452-35-7;   DrugBank:DB00311;   Drug_Central:1089;   KEGG:D02441;   LINCS:LSM-18787
 xref_mesh: MESH:D005016
 xref: PMID:10411484;   PMID:11087579;   PMID:11123998;   PMID:11906288;   PMID:12039560;   PMID:12617903;   PMID:12617904;   PMID:12643899;   PMID:12747790;   PMID:12747791;   PMID:14611846;   PMID:14640555;   PMID:14684333;   PMID:14971907;   PMID:15081039;   PMID:15139757;   PMID:15149691;   PMID:15454239;   PMID:15456265;   PMID:15501039;   PMID:15546717;   PMID:15603956;   PMID:15664816;   PMID:15686894;   PMID:15686895;   PMID:15686931;   PMID:15771455;   PMID:15837316;   PMID:15837325;   PMID:15905091;   PMID:15908201;   PMID:15908204;   PMID:16033263;   PMID:16039848;   PMID:16039853;   PMID:16165351;   PMID:16168653;   PMID:16302824;   PMID:16459077;   PMID:16539401;   PMID:16809036;   PMID:16942027;   PMID:17064072;   PMID:17125255;   PMID:17157501;   PMID:17228881;   PMID:17251018;   PMID:17276072;   PMID:17343373;   PMID:17475500;   PMID:17482815;   PMID:17540563;   PMID:17588751;   PMID:17646100;   PMID:17681760;   PMID:17826101;   PMID:18042384;   PMID:18242985;   PMID:18307288;   PMID:18359629;   PMID:18374572;   PMID:18513964;   PMID:2585443;   PMID:2810337;   PMID:6737424;   Patent:GB795174;   Patent:US2868800;   Wikipedia:Ethoxzolamide


show annotations for term's descendants           Sort by:
 
ethoxzolamide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CA1 carbonic anhydrase 1 multiple interactions EXP Ethoxzolamide binds to and results in decreased activity of CA1 protein CTD PMID:17826101 NCBI chr 8:85,327,608...85,378,113
Ensembl chr 8:85,327,608...85,379,014
JBrowse link
G CA2 carbonic anhydrase 2 multiple interactions EXP Ethoxzolamide binds to and results in decreased activity of CA2 protein CTD PMID:17826101 NCBI chr 8:85,464,007...85,481,493
Ensembl chr 8:85,463,968...85,481,493
JBrowse link
G CA3 carbonic anhydrase 3 multiple interactions EXP Ethoxzolamide binds to and results in decreased activity of CA3 protein CTD PMID:17826101 NCBI chr 8:85,438,859...85,449,040
Ensembl chr 8:85,373,436...85,449,040
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 24382
    role 24293
      application 23791
        pharmaceutical 23352
          drug 23352
            diuretic 1147
              ethoxzolamide 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 24382
    subatomic particle 24339
      composite particle 24339
        hadron 24339
          baryon 24339
            nucleon 24339
              atomic nucleus 24339
                atom 24339
                  main group element atom 24188
                    p-block element atom 24188
                      chalcogen 23222
                        oxygen atom 23095
                          oxygen molecular entity 23095
                            hydroxides 22335
                              oxoacid 21464
                                chalcogen oxoacid 12218
                                  sulfur oxoacid 11781
                                    sulfonic acid 7690
                                      sulfonic acid derivative 7690
                                        sulfonamide 3217
                                          ethoxzolamide 3
paths to the root