CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: zearalenone
Accession: CHEBI:10106
browse the term
Definition: A macrolide comprising a fourteen-membered lactone fused to 1,3-dihydroxybenzene; a potent estrogenic metabolite produced by some Giberella species.
Synonyms: exact_synonym: (3S,11E)-14,16-dihydroxy-3-methyl-3,4,5,6,9,10-hexahydro-1H-2-benzoxacyclotetradecine-1,7(8H)-dione
related_synonym: (10S)-Zearalenone; (S)-Zearalenone; (S-(E))-3,4,5,6,9,10-Hexahydro-14,16-dihydroxy-3-methyl-1H-2-benzoxacyclotetradecin-1,7(8H)-dione; 6-(10-Hydroxy-6-oxo-trans-1-undecenyl)-beta-resorcylic acid lactone; Formula=C18H22O5; InChI=1S/C18H22O5/c1-12-6-5-9-14(19)8-4-2-3-7-13-10-15(20)11-16(21)17(13)18(22)23-12/h3,7,10-12,20-21H,2,4-6,8-9H2,1H3/b7-3+/t12-/m0/s1; InChIKey=MBMQEIFVQACCCH-QBODLPLBSA-N; SMILES=C[C@H]1CCCC(=O)CCC\\C=C\\c2cc(O)cc(O)c2C(=O)O1; trans-Zearalenone
xref: AGR:IND608145868; CAS:17924-92-4; KEGG:C09981; KNApSAcK:C00003025; LIPID_MAPS_instance:LMPK04000016
xref_mesh: MESH:D015025
xref: PMID:17339071; PMID:18027362; PMID:18221829; PMID:18280460; PMID:18692541; PMID:20654554; PMID:38449531; Reaxys:4875541
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AARS1
alanyl-tRNA synthetase 1
decreases expression
ISO
Zearalenone results in decreased expression of AARS1 protein
CTD
PMID:25058043 PMID:36252740
NCBI chr16:70,252,298...70,289,506
Ensembl chr16:70,251,983...70,289,707
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ABCB1
ATP binding cassette subfamily B member 1
multiple interactions increases expression decreases expression affects expression
ISO
fulvestrant inhibits the reaction [Zearalenone results in increased expression of ABCB1A mRNA] Zearalenone results in increased expression of ABCB1 mRNA; Zearalenone results in increased expression of ABCB1A mRNA Zearalenone results in decreased expression of ABCB1A mRNA Zearalenone affects the expression of ABCB1A protein
CTD
PMID:20607812 PMID:22521637 PMID:23707492 PMID:29627501
NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323
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ABCC1
ATP binding cassette subfamily C member 1 (ABCC1 blood group)
increases expression increases transport multiple interactions affects expression decreases expression
EXP ISO
Zearalenone results in increased expression of ABCC1 protein ABCC1 protein results in increased transport of Zearalenone verlukast inhibits the reaction [ABCC1 protein results in increased transport of Zearalenone]; Zearalenone inhibits the reaction [ABCC1 protein results in increased transport of calcein AM] Zearalenone affects the expression of ABCC1 mRNA; Zearalenone affects the expression of ABCC1 protein Zearalenone results in decreased expression of ABCC1 mRNA; Zearalenone results in decreased expression of ABCC1 protein
CTD
PMID:19580841 PMID:19647055 PMID:22521637 PMID:23707492
NCBI chr16:15,949,143...16,143,053
Ensembl chr16:15,949,138...16,143,257
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ABCC2
ATP binding cassette subfamily C member 2
increases expression multiple interactions increases transport
EXP
Zearalenone results in increased expression of ABCC2 mRNA verlukast inhibits the reaction [ABCC2 protein results in increased transport of Zearalenone]; Zearalenone inhibits the reaction [ABCC2 protein results in increased transport of calcein AM]
CTD
PMID:19580841 PMID:19647055
NCBI chr10:99,782,640...99,852,594
Ensembl chr10:99,782,640...99,852,594
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ABCC3
ATP binding cassette subfamily C member 3
decreases expression multiple interactions affects expression
EXP ISO
Zearalenone results in decreased expression of ABCC3 mRNA Zearalenone inhibits the reaction [ABCC3 protein results in increased transport of calcein AM] Zearalenone affects the expression of ABCC3 mRNA; Zearalenone affects the expression of ABCC3 protein
CTD
PMID:19371625 PMID:19647055 PMID:22521637
NCBI chr17:50,634,881...50,692,253
Ensembl chr17:50,634,777...50,692,253
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ABCC4
ATP binding cassette subfamily C member 4 (PEL blood group)
multiple interactions decreases expression increases expression
ISO
fulvestrant inhibits the reaction [Zearalenone results in increased expression of ABCC4 mRNA] Zearalenone results in decreased expression of ABCC4 protein Zearalenone results in increased expression of ABCC4 mRNA; Zearalenone results in increased expression of ABCC4 protein
CTD
PMID:23707492
NCBI chr13:95,019,835...95,301,451
Ensembl chr13:95,019,835...95,301,475
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ABCC5
ATP binding cassette subfamily C member 5
multiple interactions affects expression increases expression decreases expression
ISO
fulvestrant inhibits the reaction [Zearalenone results in increased expression of ABCC5 mRNA] Zearalenone affects the expression of ABCC5 protein Zearalenone results in decreased expression of ABCC5 mRNA
CTD
PMID:23707492 PMID:29627501
NCBI chr 3:183,919,934...184,017,884
Ensembl chr 3:183,919,934...184,017,939
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ABCG2
ATP binding cassette subfamily G member 2 (JR blood group)
increases expression decreases expression increases transport
EXP ISO
Zearalenone results in increased expression of ABCG2 mRNA Zearalenone results in increased expression of ABCG2 mRNA; Zearalenone results in increased expression of ABCG2 protein Zearalenone results in decreased expression of ABCG2 mRNA; Zearalenone results in decreased expression of ABCG2 protein ABCG2 protein results in increased transport of Zearalenone
CTD
PMID:19580841 PMID:22521637 PMID:23707492 PMID:30576553
NCBI chr 4:88,090,264...88,231,626
Ensembl chr 4:88,090,150...88,231,628
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ABRACL
ABRA C-terminal like
decreases expression
ISO
Zearalenone results in decreased expression of ABRACL protein
CTD
PMID:36252740
NCBI chr 6:139,028,745...139,043,302
Ensembl chr 6:139,028,745...139,043,302
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ACACA
acetyl-CoA carboxylase alpha
increases expression
ISO
Zearalenone results in increased expression of ACACA mRNA
CTD
PMID:38159578
NCBI chr17:37,084,992...37,406,836
Ensembl chr17:37,084,992...37,406,836
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ACAT2
acetyl-CoA acetyltransferase 2
decreases expression
ISO
Zearalenone results in decreased expression of ACAT2 protein
CTD
PMID:25058043
NCBI chr 6:159,762,045...159,779,112
Ensembl chr 6:159,762,045...159,779,112
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ACKR2
atypical chemokine receptor 2
decreases expression
EXP
Zearalenone results in decreased expression of ACKR2 mRNA
CTD
PMID:19371625
NCBI chr 3:42,809,445...42,867,286
Ensembl chr 3:42,804,752...42,887,974
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ACO1
aconitase 1
decreases expression
ISO
Zearalenone results in decreased expression of ACO1 protein
CTD
PMID:36252740
NCBI chr 9:32,384,643...32,454,769
Ensembl chr 9:32,384,603...32,454,769
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ACSF2
acyl-CoA synthetase family member 2
increases expression
ISO
Zearalenone results in increased expression of ACSF2 protein
CTD
PMID:25058043
NCBI chr17:50,426,218...50,474,845
Ensembl chr17:50,426,158...50,474,845
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ACTR3
actin related protein 3
multiple interactions
ISO
[Zearalenone co-treated with CGA protein] results in increased expression of ACTR3 protein
CTD
PMID:25058043
NCBI chr 2:113,889,934...113,962,596
Ensembl chr 2:113,890,063...113,962,596
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ADAMTS9
ADAM metallopeptidase with thrombospondin type 1 motif 9
increases expression decreases expression
EXP ISO
Zearalenone results in increased expression of ADAMTS9 mRNA Zearalenone results in decreased expression of ADAMTS9 mRNA
CTD
PMID:17557909 PMID:19371625
NCBI chr 3:64,515,654...64,688,000
Ensembl chr 3:64,515,654...64,688,000
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ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
decreases expression
ISO
Zearalenone results in decreased expression of ADH7 protein
CTD
PMID:25058043
NCBI chr 4:99,412,263...99,435,342
Ensembl chr 4:99,412,261...99,435,510
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AFF3
ALF transcription elongation factor 3
increases expression
EXP
Zearalenone results in increased expression of AFF3 mRNA
CTD
PMID:36828454
NCBI chr 2:99,545,419...100,142,590
Ensembl chr 2:99,545,419...100,192,428
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AGFG2
ArfGAP with FG repeats 2
increases expression
ISO
Zearalenone results in increased expression of AGFG2 protein
CTD
PMID:36252740
NCBI chr 7:100,539,203...100,568,220
Ensembl chr 7:100,539,203...100,568,220
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AGT
angiotensinogen
increases expression
EXP
Zearalenone results in increased expression of AGT mRNA
CTD
PMID:36828454
NCBI chr 1:230,702,523...230,745,583
Ensembl chr 1:230,690,776...230,745,576
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AHR
aryl hydrocarbon receptor
increases expression
EXP
Zearalenone results in increased expression of AHR mRNA
CTD
PMID:32119988
NCBI chr 7:17,298,652...17,346,147
Ensembl chr 7:16,916,359...17,346,152
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AHSA1
activator of HSP90 ATPase activity 1
multiple interactions
ISO
[Zearalenone co-treated with CGA protein] results in increased expression of AHSA1 protein
CTD
PMID:25058043
NCBI chr14:77,457,867...77,469,472
Ensembl chr14:77,457,870...77,469,472
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AICDA
activation induced cytidine deaminase
increases expression
EXP
Zearalenone results in increased expression of AICDA mRNA
CTD
PMID:27757495
NCBI chr12:8,602,170...8,612,859
Ensembl chr12:8,602,155...8,613,242
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AIFM1
apoptosis inducing factor mitochondria associated 1
increases expression
ISO
Zearalenone results in increased expression of AIFM1 protein
CTD
PMID:25058043
NCBI chr X:130,129,362...130,165,841
Ensembl chr X:130,124,666...130,165,879
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AKR1B1
aldo-keto reductase family 1 member B
decreases expression
ISO
Zearalenone results in decreased expression of AKR1B1 protein
CTD
PMID:36252740
NCBI chr 7:134,442,350...134,459,239
Ensembl chr 7:134,442,356...134,459,284
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AKT1
AKT serine/threonine kinase 1
decreases expression increases expression decreases phosphorylation multiple interactions
ISO EXP
Zearalenone results in decreased expression of AKT1 protein Zearalenone results in increased expression of AKT1 mRNA Zearalenone results in decreased phosphorylation of AKT1 protein [Zearalenone co-treated with deoxynivalenol] results in decreased phosphorylation of AKT1 protein
CTD
PMID:31419471 PMID:32119988 PMID:32858132 PMID:35090964
NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,759
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AKT3
AKT serine/threonine kinase 3
decreases expression
ISO
Zearalenone results in decreased expression of AKT3 mRNA
CTD
PMID:30717214
NCBI chr 1:243,488,233...243,851,079
Ensembl chr 1:243,488,233...243,851,079
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ALAD
aminolevulinate dehydratase
multiple interactions decreases activity
ISO
lycopene inhibits the reaction [Zearalenone results in decreased activity of ALAD protein]
CTD
PMID:25682699
NCBI chr 9:113,386,312...113,401,284
Ensembl chr 9:113,386,312...113,401,290
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ALB
albumin
affects expression multiple interactions decreases expression
EXP ISO
Zearalenone affects the expression of ALB mRNA [deoxynivalenol co-treated with Zearalenone] affects the expression of ALB mRNA; [deoxynivalenol co-treated with Zearalenone] results in decreased expression of ALB protein; [deoxynivalenol co-treated with Zearalenone] results in increased expression of ALB mRNA Zearalenone results in decreased expression of ALB protein
CTD
PMID:28865950 PMID:28935499 PMID:34537261
NCBI chr 4:73,404,287...73,421,482
Ensembl chr 4:73,397,114...73,421,482
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ALDOB
aldolase, fructose-bisphosphate B
increases expression multiple interactions
EXP
Zearalenone results in increased expression of ALDOB mRNA [deoxynivalenol co-treated with Zearalenone] affects the expression of ALDOB mRNA; [deoxynivalenol co-treated with Zearalenone] results in increased expression of ALDOB mRNA
CTD
PMID:28865950 PMID:28935499
NCBI chr 9:101,420,560...101,435,774
Ensembl chr 9:101,420,560...101,449,664
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ALDOC
aldolase, fructose-bisphosphate C
decreases expression multiple interactions
ISO
Zearalenone results in decreased expression of ALDOA protein; Zearalenone results in decreased expression of ALDOC protein Nicotinamide Mononucleotide inhibits the reaction [Zearalenone results in decreased expression of ALDOA protein]
CTD
PMID:25058043 PMID:38159578
NCBI chr17:28,573,120...28,576,895
Ensembl chr17:28,573,115...28,576,948
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ALPG
alkaline phosphatase, germ cell
increases expression
EXP
Zearalenone results in increased expression of ALPG mRNA
CTD
PMID:19371625
NCBI chr 2:232,406,844...232,410,714
Ensembl chr 2:232,406,844...232,410,714
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ALPL
alkaline phosphatase, biomineralization associated
multiple interactions
EXP
[Zearalenone binds to ESR1 protein] which results in increased activity of ALPL protein; Fulvestrant inhibits the reaction [[Zearalenone binds to ESR1 protein] which results in increased activity of ALPL protein]
CTD
PMID:12650720
NCBI chr 1:21,508,984...21,578,410
Ensembl chr 1:21,509,397...21,578,410
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ANAPC1
anaphase promoting complex subunit 1
increases expression
EXP
Zearalenone results in increased expression of ANAPC1 mRNA
CTD
PMID:19371625
NCBI chr 2:111,766,231...111,884,193
Ensembl chr 2:111,611,639...111,884,690
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ANO1
anoctamin 1
increases expression
EXP
Zearalenone results in increased expression of ANO1 mRNA
CTD
PMID:19371625
NCBI chr11:69,965,997...70,189,530
Ensembl chr11:69,985,907...70,189,530
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ANP32A
acidic nuclear phosphoprotein 32 family member A
decreases expression
ISO
Zearalenone results in decreased expression of ANP32A protein
CTD
PMID:36252740
NCBI chr15:68,778,535...68,820,895
Ensembl chr15:68,778,535...68,820,897
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ANP32B
acidic nuclear phosphoprotein 32 family member B
decreases expression
ISO
Zearalenone results in decreased expression of ANP32B protein
CTD
PMID:36252740
NCBI chr 9:97,983,341...98,015,943
Ensembl chr 9:97,983,341...98,015,943
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ANP32E
acidic nuclear phosphoprotein 32 family member E
decreases expression
ISO
Zearalenone results in decreased expression of ANP32E protein
CTD
PMID:36252740
NCBI chr 1:150,218,417...150,236,112
Ensembl chr 1:150,218,417...150,236,156
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ANXA3
annexin A3
decreases expression
ISO
Zearalenone results in decreased expression of ANXA3 protein
CTD
PMID:25058043
NCBI chr 4:78,551,770...78,610,447
Ensembl chr 4:78,551,747...78,610,451
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ANXA5
annexin A5
affects binding
ISO
Zearalenone binds to ANXA5 protein
CTD
PMID:24412631
NCBI chr 4:121,667,946...121,696,980
Ensembl chr 4:121,667,946...121,696,995
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ANXA7
annexin A7
decreases expression
ISO
Zearalenone results in decreased expression of ANXA7 protein
CTD
PMID:25058043
NCBI chr10:73,375,101...73,414,058
Ensembl chr10:73,375,101...73,414,076
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AOC1
amine oxidase copper containing 1
increases activity multiple interactions
ISO
Zearalenone results in increased activity of AOC1 protein Rutin inhibits the reaction [Zearalenone results in increased activity of AOC1 protein]
CTD
PMID:39053873
NCBI chr 7:150,852,120...150,861,504
Ensembl chr 7:150,824,627...150,861,504
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APAF1
apoptotic peptidase activating factor 1
increases expression
ISO
Zearalenone results in increased expression of APAF1 mRNA
CTD
PMID:34537261
NCBI chr12:98,645,290...98,735,433
Ensembl chr12:98,645,149...98,735,433
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APLN
apelin
decreases expression
ISO
Zearalenone results in decreased expression of APLN mRNA
CTD
PMID:17557909
NCBI chr X:129,645,259...129,654,956
Ensembl chr X:129,645,259...129,654,956
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APOBEC1
apolipoprotein B mRNA editing enzyme catalytic subunit 1
increases expression
ISO
Zearalenone results in increased expression of APOBEC1 mRNA
CTD
PMID:17557909
NCBI chr12:7,649,400...7,670,599
Ensembl chr12:7,649,400...7,665,908
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APOE
apolipoprotein E
decreases expression
EXP
Zearalenone results in decreased expression of APOE mRNA
CTD
PMID:19371625
NCBI chr19:44,905,796...44,909,393
Ensembl chr19:44,905,791...44,909,393
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APRT
adenine phosphoribosyltransferase
decreases expression
ISO
Zearalenone results in decreased expression of APRT protein
CTD
PMID:36252740
NCBI chr16:88,809,339...88,811,928
Ensembl chr16:88,809,339...88,811,937
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AQP5
aquaporin 5
increases expression
EXP
Zearalenone results in increased expression of AQP5 mRNA
CTD
PMID:36828454
NCBI chr12:49,961,872...49,965,682
Ensembl chr12:49,961,872...49,965,682
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AR
androgen receptor
multiple interactions decreases expression decreases activity
EXP ISO
[15-acetyldeoxynivalenol co-treated with 3-acetyldeoxynivalenol co-treated with deoxynivalenol co-treated with zearalenol co-treated with Zearalenone] results in decreased activity of AR protein; Zearalenone inhibits the reaction [Metribolone results in increased activity of AR protein]; Zearalenone inhibits the reaction [Testosterone binds to and results in increased activity of AR protein] Zearalenone results in decreased expression of AR mRNA Zearalenone metabolite results in decreased activity of AR protein; Zearalenone results in decreased activity of AR protein
CTD
PMID:18324785 PMID:21803136 PMID:24412631 PMID:25455890 PMID:27481073
NCBI chr X:67,544,021...67,730,619
Ensembl chr X:67,544,021...67,730,619
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ARHGAP26
Rho GTPase activating protein 26
increases expression
EXP
Zearalenone results in increased expression of ARHGAP26 mRNA
CTD
PMID:36828454
NCBI chr 5:142,770,377...143,229,011
Ensembl chr 5:142,770,377...143,229,011
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ARNT
aryl hydrocarbon receptor nuclear translocator
increases expression
ISO
Zearalenone results in increased expression of ARNT mRNA
CTD
PMID:20607812
NCBI chr 1:150,809,713...150,876,599
Ensembl chr 1:150,809,713...150,876,708
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AS3MT
arsenite methyltransferase
decreases expression
ISO
Zearalenone results in decreased expression of AS3MT protein
CTD
PMID:36252740
NCBI chr10:102,869,470...102,901,899
Ensembl chr10:102,869,470...102,901,899
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ASAH1
N-acylsphingosine amidohydrolase 1
decreases expression
EXP
Zearalenone results in decreased expression of ASAH1 mRNA
CTD
PMID:19371625
NCBI chr 8:18,055,992...18,084,961
Ensembl chr 8:18,055,992...18,084,998
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ASRGL1
asparaginase and isoaspartyl peptidase 1
increases expression
EXP
Zearalenone results in increased expression of ASRGL1 mRNA
CTD
PMID:19371625
NCBI chr11:62,337,448...62,401,431
Ensembl chr11:62,337,448...62,393,412
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ATG5
autophagy related 5
increases expression
ISO
Zearalenone results in increased expression of ATG5 mRNA; Zearalenone results in increased expression of ATG5 protein
CTD
PMID:34537261
NCBI chr 6:106,184,476...106,325,760
Ensembl chr 6:106,045,423...106,325,791
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ATIC
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
decreases expression
ISO
Zearalenone results in decreased expression of ATIC protein
CTD
PMID:36252740
NCBI chr 2:215,312,059...215,368,592
Ensembl chr 2:215,311,956...215,349,773
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ATM
ATM serine/threonine kinase
increases expression decreases expression
ISO
Zearalenone results in increased expression of ATM mRNA Zearalenone results in decreased expression of ATM mRNA; Zearalenone results in decreased expression of ATM protein
CTD
PMID:27862621 PMID:29758222
NCBI chr11:108,223,067...108,369,102
Ensembl chr11:108,222,804...108,369,102
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ATP1A1
ATPase Na+/K+ transporting subunit alpha 1
multiple interactions
ISO
[Zearalenone co-treated with CGA protein] results in decreased expression of ATP1A1 protein
CTD
PMID:25058043
NCBI chr 1:116,373,244...116,404,774
Ensembl chr 1:116,372,668...116,410,261
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ATP5PB
ATP synthase peripheral stalk-membrane subunit b
increases expression
ISO
Zearalenone results in increased expression of ATP5PB protein
CTD
PMID:25058043
NCBI chr 1:111,449,464...111,462,773
Ensembl chr 1:111,448,864...111,462,773
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ATPAF1
ATP synthase mitochondrial F1 complex assembly factor 1
decreases expression
EXP
Zearalenone results in decreased expression of ATPAF1 mRNA
CTD
PMID:19371625
NCBI chr 1:46,632,737...46,668,557
Ensembl chr 1:46,632,737...46,673,867
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BAX
BCL2 associated X, apoptosis regulator
affects localization increases expression multiple interactions
EXP ISO
Zearalenone affects the localization of BAX protein Zearalenone results in increased expression of BAX mRNA; Zearalenone results in increased expression of BAX protein Zearalenone results in increased expression of BAX; Zearalenone results in increased expression of BAX mRNA; Zearalenone results in increased expression of BAX protein Aflatoxin B1 inhibits the reaction [Zearalenone results in increased expression of BAX mRNA]; crocin inhibits the reaction [Zearalenone results in increased expression of BAX protein]; deoxynivalenol promotes the reaction [Zearalenone results in increased expression of BAX mRNA] [Zearalenone co-treated with deoxynivalenol] results in increased expression of BAX mRNA; [Zearalenone co-treated with deoxynivalenol] results in increased expression of BAX protein
CTD
PMID:19541794 PMID:21767629 PMID:24530352 PMID:25445755 PMID:26231423 PMID:28089945 PMID:30600648 PMID:32858132 PMID:34537261 PMID:35090964 PMID:36288102 More...
NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798
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BCL2
BCL2 apoptosis regulator
decreases expression increases expression multiple interactions
ISO EXP
Zearalenone results in decreased expression of BCL2 mRNA; Zearalenone results in decreased expression of BCL2 protein Zearalenone results in increased expression of BCL2 mRNA crocin inhibits the reaction [Zearalenone results in decreased expression of BCL2 protein]
CTD
PMID:21767629 PMID:24412631 PMID:26231423 PMID:28089945 PMID:28965971 PMID:30600648 PMID:32858132 PMID:36288102 More...
NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128
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BDNF
brain derived neurotrophic factor
decreases expression
EXP
Zearalenone results in decreased expression of BDNF mRNA
CTD
PMID:24412706
NCBI chr11:27,654,893...27,722,030
Ensembl chr11:27,654,893...27,722,058
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BECN1
beclin 1
increases expression multiple interactions
ISO
Zearalenone results in increased expression of BECN1; Zearalenone results in increased expression of BECN1 protein acadesine promotes the reaction [Zearalenone results in increased expression of BECN1 protein]
CTD
PMID:24530352 PMID:31982503 PMID:32858132
NCBI chr17:42,810,132...42,824,282
Ensembl chr17:42,810,134...42,833,350
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BEND3
BEN domain containing 3
increases expression
EXP
Zearalenone results in increased expression of BEND3 mRNA
CTD
PMID:36828454
NCBI chr 6:107,065,182...107,115,515
Ensembl chr 6:107,065,182...107,115,515
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BFAR
bifunctional apoptosis regulator
increases expression
ISO
Zearalenone results in increased expression of BFAR protein
CTD
PMID:36252740
NCBI chr16:14,632,951...14,669,236
Ensembl chr16:14,632,931...14,669,236
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BICD1
BICD cargo adaptor 1
increases expression
EXP
Zearalenone results in increased expression of BICD1 mRNA
CTD
PMID:19371625
NCBI chr12:32,106,847...32,383,633
Ensembl chr12:32,106,835...32,383,633
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BID
BH3 interacting domain death agonist
multiple interactions increases activity
ISO
benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [Zearalenone results in increased activity of BID protein]
CTD
PMID:30600648
NCBI chr22:17,734,138...17,774,665
Ensembl chr22:17,734,138...17,774,770
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BIRC5
baculoviral IAP repeat containing 5
increases expression
EXP
Zearalenone results in increased expression of BIRC5 mRNA
CTD
PMID:28965971
NCBI chr17:78,214,253...78,225,635
Ensembl chr17:78,214,186...78,225,636
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BLNK
B cell linker
decreases expression
EXP
Zearalenone results in decreased expression of BLNK mRNA
CTD
PMID:36828454
NCBI chr10:96,189,171...96,271,569
Ensembl chr10:96,189,171...96,271,587
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BMF
Bcl2 modifying factor
decreases expression
EXP
Zearalenone results in decreased expression of BMF mRNA
CTD
PMID:36828454
NCBI chr15:40,087,890...40,108,879
Ensembl chr15:40,087,890...40,108,892
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BMP3
bone morphogenetic protein 3
decreases expression
EXP
Zearalenone results in decreased expression of BMP3 mRNA
CTD
PMID:36828454
NCBI chr 4:81,030,708...81,057,627
Ensembl chr 4:81,030,708...81,057,627
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BNIP1
BCL2 interacting protein 1
increases expression
EXP
Zearalenone results in increased expression of BNIP1 mRNA
CTD
PMID:19371625
NCBI chr 5:173,144,531...173,164,387
Ensembl chr 5:173,144,442...173,164,387
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BOLA2
bolA family member 2
decreases expression
ISO
Zearalenone results in decreased expression of BOLA2 protein
CTD
PMID:36252740
NCBI chr16:29,453,588...29,454,964
Ensembl chr16:30,192,932...30,194,306 Ensembl chr16:30,192,932...30,194,306
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BRAF
B-Raf proto-oncogene, serine/threonine kinase
increases expression
ISO
Zearalenone results in increased expression of BRAF protein
CTD
PMID:29758222
NCBI chr 7:140,713,328...140,924,929
Ensembl chr 7:140,719,327...140,924,929
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BRCA1
BRCA1 DNA repair associated
increases expression
ISO EXP
Zearalenone results in increased expression of BRCA1 mRNA
CTD
PMID:28552778 PMID:28965971
NCBI chr17:43,044,295...43,170,327
Ensembl chr17:43,044,295...43,170,245
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BUD31
BUD31 homolog
increases expression
ISO
Zearalenone results in increased expression of BUD31 protein
CTD
PMID:36252740
NCBI chr 7:99,408,969...99,419,616
Ensembl chr 7:99,408,641...99,419,616
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C1GALT1C1
C1GALT1 specific chaperone 1
increases expression
ISO
Zearalenone results in increased expression of C1GALT1C1 protein
CTD
PMID:36252740
NCBI chr X:120,625,674...120,630,054
Ensembl chr X:120,625,674...120,630,054
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C3
complement C3
increases expression
ISO
Zearalenone results in increased expression of C3 mRNA
CTD
PMID:17557909
NCBI chr19:6,677,704...6,720,650
Ensembl chr19:6,677,704...6,730,562
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CA12
carbonic anhydrase 12
increases expression
EXP
Zearalenone results in increased expression of CA12 mRNA
CTD
PMID:33419253 PMID:36828454
NCBI chr15:63,321,378...63,381,846
Ensembl chr15:63,321,378...63,381,846
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CA2
carbonic anhydrase 2
increases expression
EXP
Zearalenone results in increased expression of CA2 mRNA
CTD
PMID:19371625
NCBI chr 8:85,464,007...85,481,493
Ensembl chr 8:85,463,968...85,481,493
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CABLES1
Cdk5 and Abl enzyme substrate 1
increases expression
EXP
Zearalenone results in increased expression of CABLES1 mRNA
CTD
PMID:19371625 PMID:36828454
NCBI chr18:23,134,564...23,260,470
Ensembl chr18:23,134,564...23,260,470
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CADM1
cell adhesion molecule 1
increases expression
EXP
Zearalenone results in increased expression of CADM1 mRNA
CTD
PMID:36828454
NCBI chr11:115,169,236...115,504,415
Ensembl chr11:115,169,218...115,504,957
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CALR
calreticulin
multiple interactions
ISO
[Zearalenone co-treated with CGA protein] results in decreased expression of CALR protein
CTD
PMID:25058043
NCBI chr19:12,938,609...12,944,489
Ensembl chr19:12,938,578...12,944,489
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CAMKK2
calcium/calmodulin dependent protein kinase kinase 2
increases phosphorylation multiple interactions
ISO
Zearalenone results in increased phosphorylation of CAMKK2 protein 2-aminoethyl diphenylborinate inhibits the reaction [Zearalenone results in increased phosphorylation of CAMKK2 protein]; STO 609 inhibits the reaction [Zearalenone results in increased phosphorylation of CAMKK2 protein]
CTD
PMID:31982503
NCBI chr12:121,237,692...121,297,819
Ensembl chr12:121,237,675...121,298,308
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CAPN9
calpain 9
increases expression
EXP
Zearalenone results in increased expression of CAPN9 mRNA
CTD
PMID:19371625
NCBI chr 1:230,747,388...230,801,989
Ensembl chr 1:230,747,384...230,802,003
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CARHSP1
calcium regulated heat stable protein 1
decreases expression
ISO
Zearalenone results in decreased expression of CARHSP1 protein
CTD
PMID:36252740
NCBI chr16:8,852,942...8,869,006
Ensembl chr16:8,852,942...8,869,012
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CARS1
cysteinyl-tRNA synthetase 1
increases expression
EXP
Zearalenone results in increased expression of CARS1 mRNA
CTD
PMID:19371625
NCBI chr11:3,000,929...3,057,423
Ensembl chr11:3,000,922...3,057,613
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CASP1
caspase 1
multiple interactions increases expression
ISO
[Dextran Sulfate co-treated with Zearalenone] results in increased expression of CASP1 mRNA; [Dextran Sulfate co-treated with Zearalenone] results in increased expression of CASP1 protein Zearalenone results in increased expression of CASP1 mRNA; Zearalenone results in increased expression of CASP1 protein Zearalenone results in increased expression of CASP1 protein modified form 3-methyladenine promotes the reaction [[Zearalenone co-treated with Lipopolysaccharides] results in increased expression of CASP1 protein modified form]; [Zearalenone co-treated with Lipopolysaccharides] results in increased expression of CASP1 protein; [Zearalenone co-treated with Lipopolysaccharides] results in increased expression of CASP1 protein modified form; N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide inhibits the reaction [[Zearalenone co-treated with Lipopolysaccharides] results in increased expression of CASP1 protein modified form]; NLRP3 protein promotes the reaction [[Zearalenone co-treated with Lipopolysaccharides] results in increased expression of CASP1 protein modified form]; pyrrolidine dithiocarbamic acid inhibits the reaction [Zearalenone results in increased expression of CASP1 protein modified form]; Sirolimus inhibits the reaction [[Zearalenone co-treated with Lipopolysaccharides] results in increased expression of CASP1 protein modified form]
CTD
PMID:30270565 PMID:31586597
NCBI chr11:105,025,443...105,036,686
Ensembl chr11:105,025,397...105,035,250
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CASP3
caspase 3
increases activity multiple interactions increases expression increases cleavage decreases expression
EXP ISO
Zearalenone results in increased activity of CASP3 protein HERPUD1 protein promotes the reaction [Zearalenone results in increased expression of CASP3 protein modified form]; RIPK1 protein affects the reaction [Zearalenone results in increased cleavage of CASP3 protein]; scutellarin affects the reaction [RIPK1 protein affects the reaction [Zearalenone results in increased cleavage of CASP3 protein]]; scutellarin inhibits the reaction [Zearalenone results in increased cleavage of CASP3 protein]; Zearalenone promotes the reaction [deoxynivalenol results in increased expression of CASP3 mRNA] Zearalenone results in increased expression of CASP3 mRNA; Zearalenone results in increased expression of CASP3 protein modified form [Zearalenone co-treated with Aflatoxin B1] promotes the reaction [deoxynivalenol results in increased expression of CASP3 mRNA]; [Zearalenone co-treated with deoxynivalenol] results in increased expression of CASP3 protein benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [Zearalenone results in increased cleavage of CASP3 protein]; Zearalenone results in decreased expression of and results in increased cleavage of CASP3 protein Zearalenone results in decreased expression of CASP3 protein
CTD
PMID:19541794 PMID:19705349 PMID:24530352 PMID:25445755 PMID:28089945 PMID:30394307 PMID:30600648 PMID:30668976 PMID:32858132 PMID:34537261 PMID:35090964 PMID:36252740 PMID:36288102 More...
NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062
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CASP8
caspase 8
multiple interactions increases expression increases cleavage
EXP ISO
[Aflatoxin B1 co-treated with deoxynivalenol] promotes the reaction [Zearalenone results in increased expression of CASP8 mRNA]; [Zearalenone co-treated with Aflatoxin B1] promotes the reaction [deoxynivalenol results in increased expression of CASP8 mRNA]; [Zearalenone co-treated with deoxynivalenol] promotes the reaction [Aflatoxin B1 results in increased expression of CASP8 mRNA]; Zearalenone promotes the reaction [[Aflatoxin B1 co-treated with deoxynivalenol] results in increased expression of CASP8 mRNA] Zearalenone results in increased cleavage of CASP8 protein
CTD
PMID:30600648 PMID:30668976
NCBI chr 2:201,233,463...201,287,711
Ensembl chr 2:201,233,443...201,361,836
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CASP9
caspase 9
increases activity increases expression multiple interactions increases cleavage
ISO EXP
Zearalenone results in increased activity of CASP9 protein Zearalenone results in increased expression of CASP9 mRNA Zearalenone promotes the reaction [[Aflatoxin B1 co-treated with deoxynivalenol] results in increased expression of CASP9 mRNA] benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [Zearalenone results in increased cleavage of CASP9 protein] Zearalenone results in increased expression of CASP9 protein modified form
CTD
PMID:24530352 PMID:30600648 PMID:30668976 PMID:34537261 PMID:36288102
NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534
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CAT
catalase
increases expression decreases expression multiple interactions decreases activity increases activity
ISO EXP
Zearalenone results in increased expression of CAT mRNA Zearalenone results in decreased expression of CAT protein Zearalenone results in decreased expression of CAT mRNA; Zearalenone results in decreased expression of CAT protein Gallic Acid inhibits the reaction [Zearalenone results in decreased activity of CAT protein] Zearalenone results in increased activity of CAT protein [Nicotinamide Mononucleotide co-treated with Zearalenone] results in decreased expression of CAT protein; crocin inhibits the reaction [Zearalenone results in increased activity of CAT protein]
CTD
PMID:26231423 PMID:28089945 PMID:28477956 PMID:32858132 PMID:34723416 PMID:38159578 More...
NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060
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CBFA2T3
CBFA2/RUNX1 partner transcriptional co-repressor 3
increases expression
EXP
Zearalenone results in increased expression of CBFA2T3 mRNA
CTD
PMID:19371625
NCBI chr16:88,874,858...88,977,207
Ensembl chr16:88,874,858...88,977,207
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CBLN1
cerebellin 1 precursor
increases expression
EXP
Zearalenone results in increased expression of CBLN1 mRNA
CTD
PMID:36828454
NCBI chr16:49,277,917...49,281,838
Ensembl chr16:49,277,917...49,281,838
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CBR1
carbonyl reductase 1
decreases expression
ISO
Zearalenone results in decreased expression of CBR1 protein
CTD
PMID:36252740
NCBI chr21:36,070,024...36,073,164
Ensembl chr21:36,069,941...36,073,166
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CCL21
C-C motif chemokine ligand 21
increases expression
EXP
Zearalenone results in increased expression of CCL21 mRNA
CTD
PMID:27757495
NCBI chr 9:34,709,005...34,710,136
Ensembl chr 9:34,709,005...34,710,136
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CCL22
C-C motif chemokine ligand 22
increases expression
EXP
Zearalenone results in increased expression of CCL22 mRNA
CTD
PMID:27757495
NCBI chr16:57,357,909...57,366,189
Ensembl chr16:57,358,783...57,366,189
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CCN5
cellular communication network factor 5
increases expression
EXP
Zearalenone results in increased expression of CCN5 mRNA
CTD
PMID:36828454
NCBI chr20:44,714,861...44,727,811
Ensembl chr20:44,714,844...44,728,509
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CCNA1
cyclin A1
decreases expression
ISO
Zearalenone results in decreased expression of CCNA1 mRNA
CTD
PMID:24412631
NCBI chr13:36,431,517...36,442,870
Ensembl chr13:36,431,520...36,442,870
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CCNB1
cyclin B1
decreases expression
ISO
Zearalenone results in decreased expression of CCNB1 mRNA; Zearalenone results in decreased expression of CCNB1 protein
CTD
PMID:27862621 PMID:35504548
NCBI chr 5:69,167,150...69,178,245
Ensembl chr 5:69,167,135...69,178,245
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CCND1
cyclin D1
decreases expression multiple interactions increases expression
ISO
Zearalenone results in decreased expression of CCND1 mRNA [Tamoxifen co-treated with Zearalenone] results in increased expression of CCND1 protein Zearalenone results in increased expression of CCND1 mRNA; Zearalenone results in increased expression of CCND1 protein Zearalenone results in decreased expression of CCND1 protein
CTD
PMID:24412631 PMID:27473017 PMID:30138655 PMID:36288102
NCBI chr11:69,641,156...69,654,474
Ensembl chr11:69,641,156...69,654,474
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CCND2
cyclin D2
decreases expression
ISO EXP
Zearalenone results in decreased expression of CCND2 mRNA
CTD
PMID:17557909 PMID:28965971
NCBI chr12:4,273,762...4,305,353
Ensembl chr12:4,269,771...4,305,353
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CCNE1
cyclin E1
multiple interactions
EXP
[Zearalenone co-treated with Aflatoxin B1] results in increased expression of CCNE1 mRNA
CTD
PMID:28965971
NCBI chr19:29,811,991...29,824,312
Ensembl chr19:29,811,991...29,824,312
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CCR1
C-C motif chemokine receptor 1
increases expression
EXP
Zearalenone results in increased expression of CCR1 mRNA
CTD
PMID:27757495
NCBI chr 3:46,201,711...46,208,313
Ensembl chr 3:46,201,711...46,208,313
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CCR4
C-C motif chemokine receptor 4
increases expression
EXP
Zearalenone results in increased expression of CCR4 mRNA
CTD
PMID:27757495
NCBI chr 3:32,951,644...32,956,349
Ensembl chr 3:32,951,644...32,957,120
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CCT2
chaperonin containing TCP1 subunit 2
decreases expression
ISO
Zearalenone results in decreased expression of CCT2 protein
CTD
PMID:36252740
NCBI chr12:69,585,459...69,601,570
Ensembl chr12:69,585,426...69,601,570
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CCT5
chaperonin containing TCP1 subunit 5
increases expression decreases expression
ISO
Zearalenone results in increased expression of CCT5 protein Zearalenone results in decreased expression of CCT5 protein
CTD
PMID:25058043 PMID:36252740
NCBI chr 5:10,249,921...10,266,412
Ensembl chr 5:10,249,929...10,266,389
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CD274
CD274 molecule
increases expression
EXP
Zearalenone results in increased expression of CD274 mRNA
CTD
PMID:27757495
NCBI chr 9:5,450,542...5,470,554
Ensembl chr 9:5,450,503...5,470,566
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CD36
CD36 molecule (CD36 blood group)
multiple interactions decreases expression increases expression
ISO
[Zearalenone co-treated with CGA protein] results in decreased expression of CD36 protein; Nicotinamide Mononucleotide inhibits the reaction [Zearalenone results in increased expression of CD36 mRNA] Zearalenone results in decreased expression of CD36 mRNA; Zearalenone results in decreased expression of CD36 protein
CTD
PMID:25058043 PMID:32858132 PMID:38159578
NCBI chr 7:80,602,207...80,679,274
Ensembl chr 7:80,369,575...80,679,277
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CD38
CD38 molecule
increases expression multiple interactions
ISO
Zearalenone results in increased expression of CD38 mRNA Nicotinamide Mononucleotide inhibits the reaction [Zearalenone results in increased expression of CD38 mRNA]
CTD
PMID:38159578
NCBI chr 4:15,778,328...15,853,232
Ensembl chr 4:15,778,275...15,853,232
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CD86
CD86 molecule
multiple interactions
EXP
[Lipopolysaccharides co-treated with Zearalenone] results in increased expression of CD86 protein
CTD
PMID:32328699
NCBI chr 3:122,055,362...122,121,136
Ensembl chr 3:122,055,362...122,121,139
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CDC25C
cell division cycle 25C
decreases expression
ISO
Zearalenone results in decreased expression of CDC25C protein
CTD
PMID:35504548
NCBI chr 5:138,285,265...138,338,355
Ensembl chr 5:138,285,269...138,338,355
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CDC6
cell division cycle 6
decreases expression
ISO
Zearalenone results in decreased expression of CDC6 mRNA
CTD
PMID:27862621
NCBI chr17:40,287,879...40,304,657
Ensembl chr17:40,287,879...40,304,657
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CDCA7
cell division cycle associated 7
increases expression
EXP
Zearalenone results in increased expression of CDCA7 mRNA
CTD
PMID:36828454
NCBI chr 2:173,354,872...173,368,997
Ensembl chr 2:173,354,820...173,368,997
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CDH1
cadherin 1
decreases expression
EXP
Zearalenone results in decreased expression of CDH1 mRNA
CTD
PMID:33419253
NCBI chr16:68,737,292...68,835,537
Ensembl chr16:68,737,292...68,835,537
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CDK1
cyclin dependent kinase 1
decreases expression
ISO
Zearalenone results in decreased expression of CDK1 protein
CTD
PMID:34716709 PMID:35504548
NCBI chr10:60,778,331...60,794,852
Ensembl chr10:60,778,331...60,794,852
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CDK4
cyclin dependent kinase 4
increases expression
ISO
Zearalenone results in increased expression of CDK4 protein
CTD
PMID:27473017
NCBI chr12:57,747,727...57,752,310
Ensembl chr12:57,747,727...57,756,013
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CDKN1A
cyclin dependent kinase inhibitor 1A
decreases expression
ISO
Zearalenone results in decreased expression of CDKN1A mRNA
CTD
PMID:24412631
NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,397
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CDKN1C
cyclin dependent kinase inhibitor 1C
decreases expression
EXP
Zearalenone results in decreased expression of CDKN1C mRNA
CTD
PMID:28965971
NCBI chr11:2,883,218...2,885,775
Ensembl chr11:2,883,213...2,885,775
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CDKN2A
cyclin dependent kinase inhibitor 2A
decreases expression
EXP
Zearalenone results in decreased expression of CDKN2A mRNA
CTD
PMID:28965971
NCBI chr 9:21,967,752...21,995,324
Ensembl chr 9:21,967,752...21,995,301
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CEBPA
CCAAT enhancer binding protein alpha
affects expression multiple interactions
EXP
Zearalenone affects the expression of CEBPA mRNA [deoxynivalenol co-treated with Zearalenone] results in decreased expression of CEBPA mRNA
CTD
PMID:28865950
NCBI chr19:33,299,934...33,302,534
Ensembl chr19:33,299,934...33,302,534
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CEBPB
CCAAT enhancer binding protein beta
increases expression
EXP
Zearalenone results in increased expression of CEBPB mRNA
CTD
PMID:25424538
NCBI chr20:50,190,583...50,192,690
Ensembl chr20:50,190,734...50,192,690
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CEBPD
CCAAT enhancer binding protein delta
increases expression
EXP
Zearalenone results in increased expression of CEBPD mRNA
CTD
PMID:19371625
NCBI chr 8:47,736,913...47,738,164
Ensembl chr 8:47,736,913...47,738,164
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CFAP99
cilia and flagella associated protein 99
decreases expression
ISO
Zearalenone results in decreased expression of CFAP99 protein
CTD
PMID:36252740
NCBI chr 4:2,418,955...2,463,002
Ensembl chr 4:2,418,955...2,463,002
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CFI
complement factor I
increases expression
ISO
Zearalenone results in increased expression of CFI mRNA
CTD
PMID:17557909
NCBI chr 4:109,730,982...109,801,999
Ensembl chr 4:109,731,008...109,802,150
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CGA
glycoprotein hormones, alpha polypeptide
multiple interactions increases expression
EXP ISO
fulvestrant inhibits the reaction [Zearalenone results in increased expression of CGA protein] [Zearalenone co-treated with CGA protein] results in decreased expression of ATP1A1 protein; [Zearalenone co-treated with CGA protein] results in decreased expression of CALR protein; [Zearalenone co-treated with CGA protein] results in decreased expression of CD36 protein; [Zearalenone co-treated with CGA protein] results in decreased expression of HSD17B11 protein; [Zearalenone co-treated with CGA protein] results in decreased expression of MGLL protein; [Zearalenone co-treated with CGA protein] results in decreased expression of P4HB protein; [Zearalenone co-treated with CGA protein] results in decreased expression of SMPDL3B protein; [Zearalenone co-treated with CGA protein] results in decreased expression of SYAP1 protein; [Zearalenone co-treated with CGA protein] results in increased expression of ACTR3 protein; [Zearalenone co-treated with CGA protein] results in increased expression of AHSA1 protein; [Zearalenone co-treated with CGA protein] results in increased expression of DNM1L protein; [Zearalenone co-treated with CGA protein] results in increased expression of PDCD6IP protein; [Zearalenone co-treated with CGA protein] results in increased expression of PHGDH protein; [Zearalenone co-treated with CGA protein] results in increased expression of TLN1 protein; [Zearalenone co-treated with CGA protein] results in increased expression of YKT6 protein
CTD
PMID:19580841 PMID:25058043
NCBI chr 6:87,085,498...87,095,106
Ensembl chr 6:87,085,498...87,095,106
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CGB3
chorionic gonadotropin subunit beta 3
increases expression
EXP
Zearalenone results in increased expression of CGB3 protein
CTD
PMID:22310176
NCBI chr19:49,022,869...49,024,333
Ensembl chr19:49,022,869...49,024,333
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CHAC1
ChaC glutathione specific gamma-glutamylcyclotransferase 1
increases expression
EXP
Zearalenone results in increased expression of CHAC1 mRNA
CTD
PMID:25424538
NCBI chr15:40,953,471...40,956,512
Ensembl chr15:40,952,962...40,956,512
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CHAC2
ChaC glutathione specific gamma-glutamylcyclotransferase 2
increases expression
EXP
Zearalenone results in increased expression of CHAC2 mRNA
CTD
PMID:19371625
NCBI chr 2:53,767,783...53,775,196
Ensembl chr 2:53,767,804...53,775,196
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CHCHD3
coiled-coil-helix-coiled-coil-helix domain containing 3
increases expression
ISO
Zearalenone results in increased expression of CHCHD3 protein
CTD
PMID:25058043
NCBI chr 7:132,784,870...133,082,090
Ensembl chr 7:132,784,870...133,082,090
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CHEK1
checkpoint kinase 1
increases expression decreases phosphorylation
ISO
Zearalenone results in increased expression of CHEK1 protein Zearalenone results in decreased phosphorylation of CHK1 protein
CTD
PMID:34716709 PMID:35504548
NCBI chr11:125,625,136...125,681,124
Ensembl chr11:125,625,163...125,676,255
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CHEK2
checkpoint kinase 2
decreases expression
ISO
Zearalenone results in decreased expression of CHEK2 protein
CTD
PMID:35504548
NCBI chr22:28,687,743...28,741,834
Ensembl chr22:28,687,743...28,742,422
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CHORDC1
cysteine and histidine rich domain containing 1
decreases expression
ISO
Zearalenone results in decreased expression of CHORDC1 protein
CTD
PMID:36252740
NCBI chr11:90,200,429...90,223,049
Ensembl chr11:90,200,429...90,223,077
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CHUK
component of inhibitor of nuclear factor kappa B kinase complex
increases expression multiple interactions
ISO
Zearalenone results in increased expression of CHUK mRNA Rutin inhibits the reaction [Zearalenone results in increased expression of CHUK mRNA]
CTD
PMID:39053873
NCBI chr10:100,186,319...100,229,596
Ensembl chr10:100,188,300...100,229,596
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CISH
cytokine inducible SH2 containing protein
increases expression
EXP
Zearalenone results in increased expression of CISH mRNA
CTD
PMID:36828454
NCBI chr 3:50,606,489...50,611,774
Ensembl chr 3:50,606,489...50,611,774
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CKB
creatine kinase B
decreases expression
ISO
Zearalenone results in decreased expression of CKB protein
CTD
PMID:36252740
NCBI chr14:103,519,667...103,522,830
Ensembl chr14:103,519,667...103,522,833
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CLDN1
claudin 1
decreases expression multiple interactions
EXP
Zearalenone results in decreased expression of CLDN1 protein [deoxynivalenol co-treated with Zearalenone] results in decreased expression of CLDN1 mRNA; [deoxynivalenol co-treated with Zearalenone] results in decreased expression of CLDN1 protein
CTD
PMID:28865950 PMID:28935499
NCBI chr 3:190,305,707...190,322,446
Ensembl chr 3:190,305,707...190,322,446
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CLDN8
claudin 8
decreases expression
EXP
Zearalenone results in decreased expression of CLDN8 mRNA
CTD
PMID:36828454
NCBI chr21:30,214,006...30,216,097
Ensembl chr21:30,214,006...30,216,097
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CNFN
cornifelin
decreases expression
EXP
Zearalenone results in decreased expression of CNFN mRNA
CTD
PMID:19371625
NCBI chr19:42,387,019...42,390,297
Ensembl chr19:42,387,019...42,390,297
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CNN3
calponin 3
decreases expression
ISO
Zearalenone results in decreased expression of CNN3 protein
CTD
PMID:36252740
NCBI chr 1:94,896,957...94,927,110
Ensembl chr 1:94,896,949...94,927,223
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COA5
cytochrome c oxidase assembly factor 5
increases expression
ISO
Zearalenone results in increased expression of COA5 protein
CTD
PMID:36252740
NCBI chr 2:98,599,314...98,608,512
Ensembl chr 2:98,599,314...98,608,515
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COPS8
COP9 signalosome subunit 8
decreases expression
ISO
Zearalenone results in decreased expression of COPS8 protein
CTD
PMID:36252740
NCBI chr 2:237,085,889...237,100,474
Ensembl chr 2:237,085,882...237,100,474
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CORO1C
coronin 1C
increases expression
EXP
Zearalenone results in increased expression of CORO1C mRNA
CTD
PMID:19371625
NCBI chr12:108,645,109...108,731,518
Ensembl chr12:108,645,109...108,731,526
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CPT1A
carnitine palmitoyltransferase 1A
increases expression multiple interactions
ISO
Zearalenone results in increased expression of CPT1A mRNA Nicotinamide Mononucleotide inhibits the reaction [Zearalenone results in increased expression of CPT1A mRNA]
CTD
PMID:38159578
NCBI chr11:68,754,620...68,844,277
Ensembl chr11:68,754,620...68,844,410
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CPT2
carnitine palmitoyltransferase 2
increases expression
ISO
Zearalenone results in increased expression of CPT2 protein
CTD
PMID:25058043 PMID:36252740
NCBI chr 1:53,196,824...53,214,197
Ensembl chr 1:53,196,792...53,214,197
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CRABP2
cellular retinoic acid binding protein 2
decreases expression
ISO
Zearalenone results in decreased expression of CRABP2 protein
CTD
PMID:36252740
NCBI chr 1:156,699,606...156,705,784
Ensembl chr 1:156,699,606...156,705,816
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CRYBG2
crystallin beta-gamma domain containing 2
decreases expression
EXP
Zearalenone results in decreased expression of CRYBG2 mRNA
CTD
PMID:36828454
NCBI chr 1:26,321,865...26,354,130
Ensembl chr 1:26,321,698...26,360,080
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CSE1L
chromosome segregation 1 like
decreases expression
ISO
Zearalenone results in decreased expression of CSE1L protein
CTD
PMID:36252740
NCBI chr20:49,046,312...49,096,949
Ensembl chr20:49,046,246...49,096,960
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CSF2
colony stimulating factor 2
increases expression
EXP
Zearalenone results in increased expression of CSF2 mRNA
CTD
PMID:27757495
NCBI chr 5:132,073,789...132,076,170
Ensembl chr 5:132,073,789...132,076,170
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CST6
cystatin E/M
decreases expression
EXP
Zearalenone results in decreased expression of CST6 mRNA
CTD
PMID:28965971
NCBI chr11:66,012,008...66,013,505
Ensembl chr11:66,012,008...66,013,505
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CTLA4
cytotoxic T-lymphocyte associated protein 4
increases expression
EXP
Zearalenone results in increased expression of CTLA4 mRNA
CTD
PMID:27757495
NCBI chr 2:203,867,771...203,873,965
Ensembl chr 2:203,853,888...203,873,965
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CTNNB1
catenin beta 1
decreases expression
ISO
Zearalenone results in decreased expression of CTNNB1 protein
CTD
PMID:36288102
NCBI chr 3:41,199,505...41,240,443
Ensembl chr 3:41,194,741...41,260,096
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CTSD
cathepsin D
increases expression
EXP
Zearalenone results in increased expression of CTSD mRNA
CTD
PMID:28965971
NCBI chr11:1,752,755...1,763,927
Ensembl chr11:1,752,752...1,764,573
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CUTA
cutA divalent cation tolerance homolog
decreases expression
EXP
Zearalenone results in decreased expression of CUTA mRNA
CTD
PMID:19371625
NCBI chr 6:33,416,442...33,418,107
Ensembl chr 6:33,416,442...33,418,317
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CUX1
cut like homeobox 1
decreases expression
EXP
Zearalenone results in decreased expression of CUX1 mRNA
CTD
PMID:19371625
NCBI chr 7:101,816,007...102,283,958
Ensembl chr 7:101,815,904...102,283,958
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CUZD1
CUB and zona pellucida like domains 1
increases expression
ISO
Zearalenone results in increased expression of CUZD1 mRNA
CTD
PMID:17557909
NCBI chr10:122,832,158...122,845,857
Ensembl chr10:122,832,158...122,846,175
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CXCL12
C-X-C motif chemokine ligand 12
increases expression
EXP
Zearalenone results in increased expression of CXCL12 mRNA
CTD
PMID:27757495 PMID:28396216
NCBI chr10:44,370,165...44,385,097
Ensembl chr10:44,370,165...44,386,493
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CXCL8
C-X-C motif chemokine ligand 8
increases expression
EXP
Zearalenone results in increased expression of CXCL8 mRNA
CTD
PMID:27757495
NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716
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CXCL9
C-X-C motif chemokine ligand 9
increases expression
EXP
Zearalenone results in increased expression of CXCL9 mRNA
CTD
PMID:27757495
NCBI chr 4:76,001,275...76,007,509
Ensembl chr 4:76,001,275...76,007,509
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CXCR5
C-X-C motif chemokine receptor 5
increases expression
EXP
Zearalenone results in increased expression of CXCR5 mRNA
CTD
PMID:27757495
NCBI chr11:118,883,892...118,897,787
Ensembl chr11:118,883,892...118,897,787
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CYCS
cytochrome c, somatic
affects localization increases expression
EXP ISO
Zearalenone affects the localization of CYCS protein Zearalenone results in increased expression of CYCS protein
CTD
PMID:19541794 PMID:25058043
NCBI chr 7:25,118,656...25,125,260
Ensembl chr 7:25,118,656...25,125,260
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CYP11A1
cytochrome P450 family 11 subfamily A member 1
decreases expression multiple interactions decreases activity
ISO
Zearalenone results in decreased expression of CYP11A1 mRNA; Zearalenone results in decreased expression of CYP11A1 protein [Colforsin co-treated with Zearalenone] results in increased expression of CYP11A1 mRNA Zearalenone results in decreased activity of CYP11A1 protein
CTD
PMID:24512812 PMID:26783879 PMID:29669061 PMID:31419471
NCBI chr15:74,337,762...74,367,646
Ensembl chr15:74,337,759...74,367,646
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CYP17A1
cytochrome P450 family 17 subfamily A member 1
decreases expression
ISO
Zearalenone results in decreased expression of CYP17A1 mRNA
CTD
PMID:24512812 PMID:32858132
NCBI chr10:102,830,531...102,837,413
Ensembl chr10:102,830,531...102,837,472
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CYP19A1
cytochrome P450 family 19 subfamily A member 1
decreases activity decreases expression
EXP ISO
Zearalenone results in decreased activity of CYP19A1 protein Zearalenone results in decreased expression of CYP19A1 mRNA; Zearalenone results in decreased expression of CYP19A1 protein
CTD
PMID:16023337 PMID:29758222 PMID:36374910
NCBI chr15:51,208,057...51,338,596
Ensembl chr15:51,208,057...51,338,601
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CYP1A1
cytochrome P450 family 1 subfamily A member 1
multiple interactions decreases activity decreases expression
EXP
Tamoxifen inhibits the reaction [Zearalenone inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]]; Tamoxifen inhibits the reaction [Zearalenone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]]; Zearalenone inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]; Zearalenone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA] Zearalenone results in decreased activity of CYP1A1 protein Zearalenone results in decreased expression of CYP1A1 mRNA
CTD
PMID:15157572 PMID:34181028
NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536
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CYP1A2
cytochrome P450 family 1 subfamily A member 2
increases hydroxylation multiple interactions decreases activity decreases abundance
EXP
CYP1A2 protein results in increased hydroxylation of Zearalenone [CYP1A2 protein results in increased hydroxylation of Zearalenone] which results in increased chemical synthesis of Catechols Zearalenone results in decreased activity of CYP1A2 protein CYP1A2 protein results in decreased abundance of Zearalenone
CTD
PMID:19931366 PMID:38341109
NCBI chr15:74,748,845...74,756,607
Ensembl chr15:74,748,845...74,756,607
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CYP1B1
cytochrome P450 family 1 subfamily B member 1
increases activity multiple interactions
EXP
Zearalenone results in increased activity of CYP1B1 protein Zearalenone promotes the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1B1 protein]
CTD
PMID:15157572
NCBI chr 2:38,067,509...38,076,151
Ensembl chr 2:38,066,973...38,109,902
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CYP2C9
cytochrome P450 family 2 subfamily C member 9
decreases activity
EXP
Zearalenone results in decreased activity of CYP2C9 protein
CTD
PMID:38341109
NCBI chr10:94,938,658...94,990,091
Ensembl chr10:94,938,658...94,990,091
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CYP2E1
cytochrome P450 family 2 subfamily E member 1
increases expression
ISO
Zearalenone results in increased expression of CYP2E1 mRNA
CTD
PMID:20607812
NCBI chr10:133,527,363...133,539,123
Ensembl chr10:133,520,406...133,561,220
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CYP3A4
cytochrome P450 family 3 subfamily A member 4
increases expression multiple interactions decreases abundance decreases activity
EXP ISO
Zearalenone results in increased expression of CYP3A4 mRNA; Zearalenone results in increased expression of CYP3A4 protein [deoxynivalenol co-treated with Zearalenone] affects the expression of CYP3A4 mRNA; [deoxynivalenol co-treated with Zearalenone] results in decreased expression of CYP3A4 protein; [deoxynivalenol co-treated with Zearalenone] results in increased expression of CYP3A4 mRNA; [deoxynivalenol co-treated with Zearalenone] results in increased expression of CYP3A4 protein; Zearalenone promotes the reaction [NR1I2 protein results in increased expression of CYP3A4] Zearalenone results in increased expression of CYP3A2 mRNA CYP3A4 protein results in decreased abundance of Zearalenone Zearalenone results in decreased activity of CYP3A4 protein
CTD
PMID:15569515 PMID:20607812 PMID:28865950 PMID:28935499 PMID:36893891 PMID:38341109 More...
NCBI chr 7:99,756,967...99,784,184
Ensembl chr 7:99,756,960...99,784,248
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CYP4F3
cytochrome P450 family 4 subfamily F member 3
decreases expression multiple interactions
EXP
Zearalenone results in decreased expression of CYP4F3 mRNA [deoxynivalenol co-treated with Zearalenone] results in decreased expression of CYP4F3 mRNA; [deoxynivalenol co-treated with Zearalenone] results in increased expression of CYP4F3 mRNA
CTD
PMID:28865950 PMID:28935499
NCBI chr19:15,640,897...15,662,825
Ensembl chr19:15,640,897...15,662,825
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CYP51A1
cytochrome P450 family 51 subfamily A member 1
increases expression
ISO
Zearalenone results in increased expression of CYP51 protein
CTD
PMID:25058043
NCBI chr 7:92,112,153...92,134,803
Ensembl chr 7:92,084,987...92,134,803
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CYSRT1
cysteine rich tail 1
decreases expression
EXP
Zearalenone results in decreased expression of CYSRT1 mRNA
CTD
PMID:36828454
NCBI chr 9:137,225,174...137,226,315
Ensembl chr 9:137,225,174...137,226,315
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DARS1
aspartyl-tRNA synthetase 1
decreases expression
ISO
Zearalenone results in decreased expression of DARS1 protein
CTD
PMID:25058043
NCBI chr 2:135,905,881...135,985,684
Ensembl chr 2:135,905,881...135,986,100
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DAZL
deleted in azoospermia like
decreases expression
ISO
Zearalenone results in decreased expression of DAZL mRNA; Zearalenone results in decreased expression of DAZL protein
CTD
PMID:28552778 PMID:31419471
NCBI chr 3:16,586,792...16,605,423
Ensembl chr 3:16,586,792...16,670,306
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DDC
dopa decarboxylase
decreases expression
EXP
Zearalenone results in decreased expression of DDC mRNA
CTD
PMID:24412706
NCBI chr 7:50,458,442...50,565,405
Ensembl chr 7:50,458,436...50,565,405
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DDIT3
DNA damage inducible transcript 3
increases expression multiple interactions
ISO
Zearalenone results in increased expression of DDIT3 protein 2-aminoethyl diphenylborinate inhibits the reaction [Zearalenone results in increased expression of DDIT3 protein]; 4-phenylbutylamine promotes the reaction [Zearalenone results in increased expression of DDIT3 protein]
CTD
PMID:30394307 PMID:31982503
NCBI chr12:57,516,588...57,520,517
Ensembl chr12:57,516,588...57,521,737
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DDIT4L
DNA damage inducible transcript 4 like
decreases expression
EXP
Zearalenone results in decreased expression of DDIT4L mRNA
CTD
PMID:36828454
NCBI chr 4:100,185,870...100,190,468
Ensembl chr 4:100,185,870...100,190,782
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DDX25
DEAD-box helicase 25
decreases expression
ISO
Zearalenone results in decreased expression of DDX25 mRNA
CTD
PMID:24412631
NCBI chr11:125,903,328...125,928,843
Ensembl chr11:125,903,348...125,943,702
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DDX4
DEAD-box helicase 4
decreases expression
ISO
Zearalenone results in decreased expression of DDX4 protein; Zearalenone results in decreased expression of VASA protein
CTD
PMID:28089945 PMID:31419471
NCBI chr 5:55,738,061...55,817,157
Ensembl chr 5:55,738,017...55,817,157
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DEPTOR
DEP domain containing MTOR interacting protein
increases expression
EXP
Zearalenone results in increased expression of DEPTOR mRNA
CTD
PMID:33419253 PMID:36828454
NCBI chr 8:119,873,722...120,050,918
Ensembl chr 8:119,873,717...120,050,918
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DGAT1
diacylglycerol O-acyltransferase 1
multiple interactions increases expression
ISO
Nicotinamide Mononucleotide inhibits the reaction [Zearalenone results in increased expression of DGAT1 mRNA]
CTD
PMID:38159578
NCBI chr 8:144,314,584...144,326,852
Ensembl chr 8:144,314,584...144,326,910
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DGAT2
diacylglycerol O-acyltransferase 2
increases expression multiple interactions
ISO
Zearalenone results in increased expression of DGAT2 mRNA Nicotinamide Mononucleotide inhibits the reaction [Zearalenone results in increased expression of DGAT2 mRNA]
CTD
PMID:38159578
NCBI chr11:75,768,778...75,801,534
Ensembl chr11:75,759,512...75,801,535
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DHRS2
dehydrogenase/reductase 2
increases expression
EXP
Zearalenone results in increased expression of DHRS2 mRNA
CTD
PMID:36828454
NCBI chr14:23,630,115...23,645,639
Ensembl chr14:23,630,115...23,645,639
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DHRS3
dehydrogenase/reductase 3
increases expression
EXP
Zearalenone results in increased expression of DHRS3 mRNA
CTD
PMID:19371625
NCBI chr 1:12,567,910...12,618,210
Ensembl chr 1:12,567,909...12,620,133
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DIO3OS
DIO3 opposite strand upstream RNA
decreases expression
ISO
Zearalenone results in decreased expression of DIO3OS mRNA
CTD
PMID:30790392
NCBI chr14:101,552,221...101,560,422
Ensembl chr14:101,552,221...101,620,355
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DIRAS3
DIRAS family GTPase 3
increases expression
EXP
Zearalenone results in increased expression of DIRAS3 mRNA
CTD
PMID:36828454
NCBI chr 1:68,045,962...68,050,627
Ensembl chr 1:68,045,886...68,051,717
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DKK2
dickkopf WNT signaling pathway inhibitor 2
decreases expression
ISO
Zearalenone results in decreased expression of DKK2 mRNA
CTD
PMID:27862621
NCBI chr 4:106,921,802...107,036,313
Ensembl chr 4:106,921,802...107,283,806
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DLD
dihydrolipoamide dehydrogenase
increases expression
ISO
Zearalenone results in increased expression of DLD protein
CTD
PMID:25058043
NCBI chr 7:107,891,107...107,921,198
Ensembl chr 7:107,891,162...107,931,730
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DMBT1
deleted in malignant brain tumors 1
increases expression
ISO
Zearalenone results in increased expression of DMBT1 mRNA
CTD
PMID:17557909
NCBI chr10:122,560,754...122,643,736
Ensembl chr10:122,560,665...122,643,736
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DNM1L
dynamin 1 like
multiple interactions
ISO
[Zearalenone co-treated with CGA protein] results in increased expression of DNM1L protein
CTD
PMID:25058043
NCBI chr12:32,679,301...32,745,650
Ensembl chr12:32,679,200...32,745,650
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DNMT1
DNA methyltransferase 1
increases expression
EXP
Zearalenone results in increased expression of DNMT1 mRNA
CTD
PMID:32119988
NCBI chr19:10,133,346...10,194,953
Ensembl chr19:10,133,342...10,231,286
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DOHH
deoxyhypusine hydroxylase
decreases expression
ISO
Zearalenone results in decreased expression of DOHH protein
CTD
PMID:36252740
NCBI chr19:3,490,824...3,500,674
Ensembl chr19:3,490,821...3,500,674
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DOK4
docking protein 4
increases expression
EXP
Zearalenone results in increased expression of DOK4 mRNA
CTD
PMID:19371625
NCBI chr16:57,471,922...57,487,322
Ensembl chr16:57,471,922...57,487,327
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DPYSL2
dihydropyrimidinase like 2
decreases expression
ISO
Zearalenone results in decreased expression of DPYSL2 protein
CTD
PMID:25058043
NCBI chr 8:26,514,031...26,658,175
Ensembl chr 8:26,514,031...26,658,178
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DSTN
destrin, actin depolymerizing factor
decreases expression
ISO
Zearalenone results in decreased expression of DSTN protein
CTD
PMID:36252740
NCBI chr20:17,570,075...17,609,919
Ensembl chr20:17,570,075...17,609,919
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DUSP2
dual specificity phosphatase 2
increases expression
EXP
Zearalenone results in increased expression of DUSP2 mRNA
CTD
PMID:36828454
NCBI chr 2:96,143,169...96,145,440
Ensembl chr 2:96,143,166...96,145,440
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DVL1
dishevelled segment polarity protein 1
increases expression
ISO
Zearalenone results in increased expression of DVL1 mRNA
CTD
PMID:32858132
NCBI chr 1:1,335,278...1,349,418
Ensembl chr 1:1,335,276...1,349,418
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DYNC1LI2
dynein cytoplasmic 1 light intermediate chain 2
decreases expression
ISO
Zearalenone results in decreased expression of DYNC1LI2 protein
CTD
PMID:36252740
NCBI chr16:66,720,893...66,751,609
Ensembl chr16:66,720,893...66,751,609
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ECE2
endothelin converting enzyme 2
decreases expression
ISO
Zearalenone results in decreased expression of ECE2 protein
CTD
PMID:36252740
NCBI chr 3:184,276,022...184,293,031
Ensembl chr 3:184,276,011...184,293,031
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ECH1
enoyl-CoA hydratase 1
decreases expression
EXP
Zearalenone results in decreased expression of ECH1 mRNA
CTD
PMID:19371625
NCBI chr19:38,815,422...38,831,794
Ensembl chr19:38,815,422...38,831,841
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ECHS1
enoyl-CoA hydratase, short chain 1
decreases expression
ISO
Zearalenone results in decreased expression of ECHS1 mRNA; Zearalenone results in decreased expression of ECHS1 protein
CTD
PMID:32858132
NCBI chr10:133,362,485...133,373,354
Ensembl chr10:133,362,485...133,373,354
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EEF1B2
eukaryotic translation elongation factor 1 beta 2
decreases expression
ISO
Zearalenone results in decreased expression of EEF1B2 protein
CTD
PMID:36252740
NCBI chr 2:206,159,609...206,162,928
Ensembl chr 2:206,159,585...206,162,928
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EFL1
elongation factor like GTPase 1
decreases expression
ISO
Zearalenone results in decreased expression of EFL1 protein
CTD
PMID:36252740
NCBI chr15:82,130,233...82,262,734
Ensembl chr15:82,130,206...82,262,773
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EGR1
early growth response 1
increases expression
EXP
Zearalenone results in increased expression of EGR1 mRNA
CTD
PMID:36828454
NCBI chr 5:138,465,479...138,469,303
Ensembl chr 5:138,465,479...138,469,303
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EHMT2
euchromatic histone lysine methyltransferase 2
increases expression
EXP
Zearalenone results in increased expression of EHMT2 mRNA
CTD
PMID:32119988
NCBI chr 6:31,879,759...31,897,698
Ensembl chr 6:31,879,759...31,897,698
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EIF1AX
eukaryotic translation initiation factor 1A X-linked
decreases expression
ISO
Zearalenone results in decreased expression of EIF1AX protein
CTD
PMID:36252740
NCBI chr X:20,124,525...20,141,838
Ensembl chr X:20,124,525...20,141,838
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EIF4EBP1
eukaryotic translation initiation factor 4E binding protein 1
decreases phosphorylation
ISO
Zearalenone results in decreased phosphorylation of EIF4EBP1 protein
CTD
PMID:32858132
NCBI chr 8:38,030,534...38,060,365
Ensembl chr 8:38,030,534...38,060,365
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ELOVL3
ELOVL fatty acid elongase 3
multiple interactions increases expression
ISO
Nicotinamide Mononucleotide inhibits the reaction [Zearalenone results in increased expression of ELOVL3 mRNA]
CTD
PMID:38159578
NCBI chr10:102,224,767...102,229,589
Ensembl chr10:102,226,299...102,229,589
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EP300
E1A binding protein p300
decreases expression
ISO
Zearalenone results in decreased expression of EP300 protein
CTD
PMID:36288102
NCBI chr22:41,092,592...41,180,077
Ensembl chr22:41,092,510...41,180,077
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EPAS1
endothelial PAS domain protein 1
increases expression
ISO
Zearalenone results in increased expression of EPAS1 mRNA
CTD
PMID:30138655
NCBI chr 2:46,297,407...46,386,697
Ensembl chr 2:46,293,667...46,386,697
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EPB41L2
erythrocyte membrane protein band 4.1 like 2
increases expression
EXP
Zearalenone results in increased expression of EPB41L2 mRNA
CTD
PMID:19371625
NCBI chr 6:130,839,347...131,063,245
Ensembl chr 6:130,839,347...131,063,322
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EPHB3
EPH receptor B3
decreases expression
EXP
Zearalenone results in decreased expression of EPHB3 mRNA
CTD
PMID:36828454
NCBI chr 3:184,561,785...184,582,408
Ensembl chr 3:184,561,785...184,582,408
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EPHB4
EPH receptor B4
increases expression
ISO
Zearalenone results in increased expression of EPHB4 protein
CTD
PMID:36252740
NCBI chr 7:100,802,565...100,827,523
Ensembl chr 7:100,802,565...100,827,523
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EPN3
epsin 3
decreases expression
EXP
Zearalenone results in decreased expression of EPN3 mRNA
CTD
PMID:19371625
NCBI chr17:50,532,735...50,543,750
Ensembl chr17:50,532,682...50,543,750
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ERBB3
erb-b2 receptor tyrosine kinase 3
decreases expression
EXP
Zearalenone results in decreased expression of ERBB3 mRNA
CTD
PMID:19371625
NCBI chr12:56,080,108...56,103,505
Ensembl chr12:56,076,799...56,103,505
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ERCC3
ERCC excision repair 3, TFIIH core complex helicase subunit
increases expression
EXP
Zearalenone results in increased expression of ERCC3 mRNA
CTD
PMID:19371625
NCBI chr 2:127,257,290...127,294,144
Ensembl chr 2:127,257,290...127,294,166
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ERG
ETS transcription factor ERG
increases expression
EXP
Zearalenone results in increased expression of ERG mRNA
CTD
PMID:36828454
NCBI chr21:38,367,261...38,661,783
Ensembl chr21:38,380,027...38,661,780
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ERICH3
glutamate rich 3
increases expression
EXP
Zearalenone results in increased expression of ERICH3 mRNA
CTD
PMID:36828454
NCBI chr 1:74,568,123...74,674,343
Ensembl chr 1:74,568,117...74,673,792
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ERP27
endoplasmic reticulum protein 27
decreases expression
EXP
Zearalenone results in decreased expression of ERP27 mRNA
CTD
PMID:19371625
NCBI chr12:14,914,039...14,938,537
Ensembl chr12:14,914,039...14,938,537
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ESCO1
establishment of sister chromatid cohesion N-acetyltransferase 1
increases expression
EXP
Zearalenone results in increased expression of ESCO1 mRNA
CTD
PMID:32119988
NCBI chr18:21,529,284...21,600,704
Ensembl chr18:21,529,281...21,600,884
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ESPN
espin
increases expression
EXP
Zearalenone results in increased expression of ESPN mRNA
CTD
PMID:19371625
NCBI chr 1:6,424,776...6,461,370
Ensembl chr 1:6,424,776...6,461,367
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ESR1
estrogen receptor 1
multiple interactions increases activity affects binding affects expression decreases expression affects response to substance
EXP ISO
[Zearalenone binds to ESR1 protein] which results in increased activity of ALPL protein; Fulvestrant inhibits the reaction [[Zearalenone binds to ESR1 protein] which results in increased activity of ALPL protein]; Zearalenone analog promotes the reaction [ESR1 protein binds to and results in increased activity of NCOA2 protein]; Zearalenone binds to and results in decreased activity of ESR1 protein; Zearalenone binds to and results in increased activity of ESR1 protein; Zearalenone promotes the reaction [ESR1 protein alternative form binds to ESR1 protein alternative form]; Zearalenone promotes the reaction [ESR1 protein binds to and results in increased activity of NCOA2 protein]; Zearalenone promotes the reaction [NCOA2 protein binds to ESR1 protein] Zearalenone results in increased activity of ESR1 protein Zearalenone affects the expression of ESR1 mRNA; Zearalenone affects the expression of ESR1 protein Zearalenone analog binds to ESR1 protein; Zearalenone binds to ESR1 protein Zearalenone metabolite results in increased activity of ESR1 protein; Zearalenone results in increased activity of ESR1 protein Zearalenone results in decreased expression of ESR1 mRNA; Zearalenone results in decreased expression of ESR1 protein ESR1 protein affects the susceptibility to Zearalenone
CTD
PMID:9751507 PMID:11162928 PMID:11331656 PMID:11750080 PMID:12598185 PMID:12650720 PMID:15084758 PMID:15169976 PMID:19233257 PMID:19913605 PMID:20209442 PMID:22494775 PMID:22521637 PMID:25455890 PMID:27862621 PMID:28396216 PMID:28807876 PMID:28965971 PMID:29627501 PMID:30270565 PMID:31419471 PMID:33049310 PMID:33419253 More...
NCBI chr 6:151,656,672...152,129,619
Ensembl chr 6:151,656,691...152,129,619
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ESR2
estrogen receptor 2
multiple interactions affects binding decreases expression increases expression
EXP ISO
Zearalenone analog promotes the reaction [ESR2 protein binds to and results in increased activity of NCOA2 protein]; Zearalenone binds to and results in decreased activity of ESR2 protein; Zearalenone binds to and results in increased activity of ESR2 protein; Zearalenone promotes the reaction [ESR2 protein binds to and results in increased activity of NCOA2 protein] Zearalenone binds to ESR2 protein Zearalenone analog binds to ESR2 protein; Zearalenone binds to ESR2 protein [bisphenol A co-treated with Zearalenone co-treated with Arsenic co-treated with enzacamene co-treated with Estradiol co-treated with Triiodothyronine] results in decreased expression of ESR2 mRNA; [bisphenol A co-treated with Zearalenone co-treated with Arsenic co-treated with enzacamene] results in increased expression of ESR2 mRNA; [Estradiol co-treated with Triiodothyronine] promotes the reaction [Zearalenone results in decreased expression of ESR2 mRNA]; [Zearalenone co-treated with Estradiol co-treated with Triiodothyronine] results in decreased expression of ESR2 mRNA; [Zearalenone results in increased susceptibility to [Estradiol co-treated with Triiodothyronine]] which results in decreased expression of ESR2 mRNA Zearalenone results in increased expression of ESR2 mRNA Dextran Sulfate promotes the reaction [Zearalenone results in increased expression of ESR2 mRNA]
CTD
PMID:9751507 PMID:15084758 PMID:15169976 PMID:19913605 PMID:27338438 PMID:28807876 PMID:30270565 PMID:33049310 More...
NCBI chr14:64,226,707...64,338,613
Ensembl chr14:64,084,232...64,338,112
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ETFB
electron transfer flavoprotein subunit beta
increases expression
ISO
Zearalenone results in increased expression of ETFB protein
CTD
PMID:25058043
NCBI chr19:51,345,155...51,366,388
Ensembl chr19:51,345,169...51,366,388
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ETFDH
electron transfer flavoprotein dehydrogenase
increases expression
ISO
Zearalenone results in increased expression of ETFDH protein
CTD
PMID:25058043
NCBI chr 4:158,672,296...158,709,623
Ensembl chr 4:158,671,968...158,710,742
G
ETNK2
ethanolamine kinase 2
increases expression
EXP
Zearalenone results in increased expression of ETNK2 mRNA
CTD
PMID:19371625
NCBI chr 1:204,131,062...204,152,044
Ensembl chr 1:204,131,062...204,152,044
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FABP1
fatty acid binding protein 1
increases expression
EXP
Zearalenone results in increased expression of FABP1 mRNA
CTD
PMID:32119988
NCBI chr 2:88,122,982...88,128,062
Ensembl chr 2:88,122,982...88,128,062
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FAM107A
family with sequence similarity 107 member A
decreases expression
EXP
Zearalenone results in decreased expression of FAM107A mRNA
CTD
PMID:19371625
NCBI chr 3:58,564,117...58,627,610
Ensembl chr 3:58,564,117...58,627,610
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FAS
Fas cell surface death receptor
increases expression
ISO
Zearalenone results in increased expression of FAS mRNA; Zearalenone results in increased expression of FAS protein
CTD
PMID:30600648
NCBI chr10:88,964,050...89,017,059
Ensembl chr10:88,953,813...89,029,605
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FASLG
Fas ligand
increases expression
ISO
Zearalenone results in increased expression of FASLG mRNA; Zearalenone results in increased expression of FASLG protein
CTD
PMID:30600648
NCBI chr 1:172,659,103...172,666,876
Ensembl chr 1:172,659,103...172,666,876
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FASN
fatty acid synthase
multiple interactions increases expression
ISO
Nicotinamide Mononucleotide inhibits the reaction [Zearalenone results in increased expression of FASN mRNA]
CTD
PMID:38159578
NCBI chr17:82,078,338...82,098,236
Ensembl chr17:82,078,338...82,098,294
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FDX1
ferredoxin 1
decreases expression
ISO
Zearalenone results in decreased expression of FDX1 mRNA; Zearalenone results in decreased expression of FDX1 protein
CTD
PMID:29758222
NCBI chr11:110,429,331...110,464,884
Ensembl chr11:110,429,948...110,464,884
G
FIGLA
folliculogenesis specific bHLH transcription factor
decreases expression
ISO
Zearalenone results in decreased expression of FIGLA mRNA
CTD
PMID:28089945
NCBI chr 2:70,777,310...70,790,643
Ensembl chr 2:70,777,310...70,790,643
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FILIP1L
filamin A interacting protein 1 like
decreases expression
EXP
Zearalenone results in decreased expression of FILIP1L mRNA
CTD
PMID:36828454
NCBI chr 3:99,828,811...100,114,501
Ensembl chr 3:99,828,811...100,114,513
G
FKBP4
FKBP prolyl isomerase 4
decreases expression
ISO
Zearalenone results in decreased expression of FKBP4 protein
CTD
PMID:25058043
NCBI chr12:2,794,970...2,805,423
Ensembl chr12:2,794,970...2,805,423
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FKBP5
FKBP prolyl isomerase 5
decreases expression
ISO
Zearalenone results in decreased expression of FKBP5 mRNA
CTD
PMID:24412631
NCBI chr 6:35,573,590...35,728,583
Ensembl chr 6:35,573,585...35,728,583
G
FN3KRP
fructosamine 3 kinase related protein
decreases expression
ISO
Zearalenone results in decreased expression of FN3KRP protein
CTD
PMID:36252740
NCBI chr17:82,716,706...82,728,013
Ensembl chr17:82,716,706...82,730,328
G
FNDC5
fibronectin type III domain containing 5
decreases expression
EXP
Zearalenone results in decreased expression of FNDC5 mRNA
CTD
PMID:19371625
NCBI chr 1:32,862,268...32,872,484
Ensembl chr 1:32,862,268...32,872,482
G
FOLR1
folate receptor alpha
decreases expression
EXP
Zearalenone results in decreased expression of FOLR1 mRNA
CTD
PMID:19371625
NCBI chr11:72,189,709...72,196,323
Ensembl chr11:72,189,558...72,196,323
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FOS
Fos proto-oncogene, AP-1 transcription factor subunit
increases expression
ISO
Zearalenone results in increased expression of FOS protein
CTD
PMID:27473017
NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,283,190
G
FOXD1
forkhead box D1
increases expression
EXP
Zearalenone results in increased expression of FOXD1 mRNA
CTD
PMID:19371625
NCBI chr 5:73,446,266...73,448,777
Ensembl chr 5:73,444,827...73,448,777
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FOXJ1
forkhead box J1
decreases expression
EXP
Zearalenone results in decreased expression of FOXJ1 mRNA
CTD
PMID:19371625
NCBI chr17:76,136,333...76,141,245
Ensembl chr17:76,136,333...76,141,245
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FOXO1
forkhead box O1
decreases expression
ISO
Zearalenone results in decreased expression of FOXO1 mRNA
CTD
PMID:30717214
NCBI chr13:40,555,667...40,666,641
Ensembl chr13:40,555,667...40,666,641
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FOXO3
forkhead box O3
decreases expression
ISO
Zearalenone results in decreased expression of FOXO3 mRNA
CTD
PMID:30717214
NCBI chr 6:108,559,825...108,684,774
Ensembl chr 6:108,559,835...108,684,774
G
FSHB
follicle stimulating hormone subunit beta
decreases expression multiple interactions
ISO
Zearalenone results in decreased expression of FSHB protein Gallic Acid inhibits the reaction [Zearalenone results in decreased expression of FSHB protein]
CTD
PMID:32858132 PMID:34723416
NCBI chr11:30,231,014...30,235,194
Ensembl chr11:30,231,014...30,235,261
G
FSHR
follicle stimulating hormone receptor
decreases expression
ISO
Zearalenone results in decreased expression of FSHR mRNA; Zearalenone results in decreased expression of FSHR protein
CTD
PMID:29669061
NCBI chr 2:48,962,157...49,154,515
Ensembl chr 2:48,962,157...49,154,527
G
G0S2
G0/G1 switch 2
increases expression
EXP
Zearalenone results in increased expression of G0S2 mRNA
CTD
PMID:19371625
NCBI chr 1:209,675,412...209,676,390
Ensembl chr 1:209,675,412...209,676,390
G
G6PD
glucose-6-phosphate dehydrogenase
multiple interactions decreases activity
ISO
Gallic Acid inhibits the reaction [Zearalenone results in decreased activity of G6PD protein]
CTD
PMID:34723416
NCBI chr X:154,531,390...154,547,569
Ensembl chr X:154,517,825...154,547,572
G
GADD45A
growth arrest and DNA damage inducible alpha
increases expression
ISO
Zearalenone results in increased expression of GADD45A mRNA
CTD
PMID:27862621
NCBI chr 1:67,685,201...67,688,334
Ensembl chr 1:67,685,201...67,688,334
G
GALNT4
polypeptide N-acetylgalactosaminyltransferase 4
increases expression
EXP
Zearalenone results in increased expression of GALNT4 mRNA
CTD
PMID:19371625
NCBI chr12:89,519,412...89,524,796
Ensembl chr12:89,519,412...89,524,796
G
GALR2
galanin receptor 2
decreases expression
EXP
Zearalenone results in decreased expression of GALR2 mRNA
CTD
PMID:19371625
NCBI chr17:76,071,962...76,077,537
Ensembl chr17:76,074,781...76,077,537
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GAP43
growth associated protein 43
decreases expression
ISO
Zearalenone results in decreased expression of GAP43 mRNA
CTD
PMID:17557909
NCBI chr 3:115,623,510...115,721,483
Ensembl chr 3:115,623,510...115,721,490
G
GAPDH
glyceraldehyde-3-phosphate dehydrogenase
decreases expression
ISO
Zearalenone results in decreased expression of GAPDH protein
CTD
PMID:36252740
NCBI chr12:6,534,517...6,538,371
Ensembl chr12:6,534,512...6,538,374
G
GARS1
glycyl-tRNA synthetase 1
decreases expression
ISO
Zearalenone results in decreased expression of GARS1 protein
CTD
PMID:36252740
NCBI chr 7:30,594,735...30,634,033
Ensembl chr 7:30,580,533...30,634,033
G
GDF10
growth differentiation factor 10
decreases expression
ISO
Zearalenone results in decreased expression of GDF10 mRNA
CTD
PMID:17557909
NCBI chr10:47,300,197...47,313,577
Ensembl chr10:47,300,197...47,313,577
G
GDNF
glial cell derived neurotrophic factor
decreases expression
ISO
Zearalenone results in decreased expression of GDNF protein
CTD
PMID:31419471
NCBI chr 5:37,812,677...37,840,041
Ensembl chr 5:37,812,677...37,840,041
G
GDPD5
glycerophosphodiester phosphodiesterase domain containing 5
increases expression
EXP
Zearalenone results in increased expression of GDPD5 mRNA
CTD
PMID:19371625
NCBI chr11:75,434,640...75,525,941
Ensembl chr11:75,434,640...75,525,941
G
GFRA2
GDNF family receptor alpha 2
decreases expression
ISO
Zearalenone results in decreased expression of GFRA2 mRNA
CTD
PMID:17557909
NCBI chr 8:21,690,398...21,812,345
Ensembl chr 8:21,690,398...21,812,357
G
GINS3
GINS complex subunit 3
decreases expression
EXP
Zearalenone results in decreased expression of GINS3 mRNA
CTD
PMID:19371625
NCBI chr16:58,392,471...58,406,147
Ensembl chr16:58,295,080...58,406,147
G
GJA1
gap junction protein alpha 1
decreases expression
ISO
Zearalenone results in decreased expression of GJA1 protein
CTD
PMID:27473017
NCBI chr 6:121,435,646...121,449,727
Ensembl chr 6:121,435,595...121,449,727
G
GJB1
gap junction protein beta 1
decreases expression
ISO
Zearalenone results in decreased expression of GJB1 protein
CTD
PMID:27473017
NCBI chr X:71,215,239...71,225,516
Ensembl chr X:71,212,811...71,225,516
G
GJB2
gap junction protein beta 2
increases expression
ISO
Zearalenone results in increased expression of GJB2 mRNA
CTD
PMID:17557909
NCBI chr13:20,187,470...20,192,938
Ensembl chr13:20,187,463...20,192,938
G
GLG1
golgi glycoprotein 1
increases expression
ISO
Zearalenone results in increased expression of GLG1 protein
CTD
PMID:36252740
NCBI chr16:74,447,440...74,607,114
Ensembl chr16:74,447,427...74,607,144
G
GLRX2
glutaredoxin 2
increases expression
EXP
Zearalenone results in increased expression of GLRX2 mRNA
CTD
PMID:19371625
NCBI chr 1:193,096,465...193,106,114
Ensembl chr 1:193,090,866...193,106,114
G
GNRH1
gonadotropin releasing hormone 1
decreases expression
ISO
Zearalenone results in decreased expression of GNRH1 mRNA
CTD
PMID:29627501
NCBI chr 8:25,419,258...25,425,040
Ensembl chr 8:25,419,258...25,424,654
G
GNRHR
gonadotropin releasing hormone receptor
decreases expression
ISO
Zearalenone results in decreased expression of GNRHR protein
CTD
PMID:29627501
NCBI chr 4:67,737,118...67,754,388
Ensembl chr 4:67,737,118...67,754,388
G
GNRHR2
gonadotropin releasing hormone receptor 2 (pseudogene)
decreases expression
EXP
Zearalenone results in decreased expression of GNRHR2 mRNA
CTD
PMID:36828454
NCBI chr 1:145,919,013...145,925,341
Ensembl chr 1:145,919,013...145,925,341 Ensembl chr 1:145,919,013...145,925,341
G
GOT2
glutamic-oxaloacetic transaminase 2
increases expression
ISO
Zearalenone results in increased expression of GOT2 protein
CTD
PMID:25058043
NCBI chr16:58,707,131...58,734,316
Ensembl chr16:58,707,131...58,734,342
G
GPER1
G protein-coupled estrogen receptor 1
affects binding decreases expression
EXP
Zearalenone binds to GPER1 protein Zearalenone results in decreased expression of GPER1 mRNA
CTD
PMID:17088055 PMID:28965971
NCBI chr 7:1,087,118...1,093,810
Ensembl chr 7:1,082,208...1,093,815
G
GPR142
G protein-coupled receptor 142
increases expression
EXP
Zearalenone results in increased expression of GPR142 mRNA
CTD
PMID:19371625
NCBI chr17:74,367,506...74,372,600
Ensembl chr17:74,367,458...74,372,600
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GPT
glutamic--pyruvic transaminase
decreases expression multiple interactions increases activity increases expression
ISO
Zearalenone results in decreased expression of GPT protein 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [corynoline inhibits the reaction [Zearalenone results in increased activity of GPT protein]]; corynoline inhibits the reaction [Zearalenone results in increased activity of GPT protein]; crocin inhibits the reaction [Zearalenone results in increased expression of GPT protein]; Plant Extracts inhibits the reaction [Zearalenone results in increased expression of GPT protein]; Rutin inhibits the reaction [Zearalenone results in increased activity of GPT protein]; Zearalenone inhibits the reaction [Aflatoxin B1 results in increased activity of GPT protein]
CTD
PMID:17385802 PMID:25058043 PMID:25445755 PMID:26231423 PMID:36161741 PMID:39053873 More...
NCBI chr 8:144,503,068...144,507,172
Ensembl chr 8:144,502,973...144,507,174
G
GPX1
glutathione peroxidase 1
decreases expression
ISO
Zearalenone results in decreased expression of GPX1 mRNA; Zearalenone results in decreased expression of GPX1 protein
CTD
PMID:32858132
NCBI chr 3:49,357,176...49,358,353
Ensembl chr 3:49,357,174...49,358,605
G
GRB7
growth factor receptor bound protein 7
decreases expression
EXP
Zearalenone results in decreased expression of GRB7 mRNA
CTD
PMID:28965971
NCBI chr17:39,737,938...39,747,285
Ensembl chr17:39,737,927...39,747,291
G
GREB1
growth regulating estrogen receptor binding 1
increases expression
EXP
Zearalenone results in increased expression of GREB1 mRNA
CTD
PMID:19371625 PMID:22494775 PMID:28807876 PMID:33419253 PMID:36828454
NCBI chr 2:11,482,888...11,642,788
Ensembl chr 2:11,482,341...11,642,788
G
GSDMD
gasdermin D
decreases expression
EXP
Zearalenone results in decreased expression of GSDMD mRNA
CTD
PMID:19371625
NCBI chr 8:143,553,387...143,563,062
Ensembl chr 8:143,553,207...143,563,062
G
GSPT1
G1 to S phase transition 1
decreases expression
ISO
Zearalenone results in decreased expression of GSPT1 protein
CTD
PMID:36252740
NCBI chr16:11,868,128...11,916,654
Ensembl chr16:11,868,128...11,916,082
G
GSR
glutathione-disulfide reductase
multiple interactions decreases activity
ISO
lycopene inhibits the reaction [Zearalenone results in decreased activity of GSR protein]
CTD
PMID:25682699
NCBI chr 8:30,678,066...30,727,846
Ensembl chr 8:30,678,066...30,727,846
G
GSTM2
glutathione S-transferase mu 2
decreases expression
ISO
Zearalenone results in decreased expression of GSTM2 protein
CTD
PMID:36252740
NCBI chr 1:109,668,057...109,683,997
Ensembl chr 1:109,668,022...109,709,551
G
GSTP1
glutathione S-transferase pi 1
decreases expression
ISO
Zearalenone results in decreased expression of GSTP1 protein
CTD
PMID:36252740
NCBI chr11:67,583,812...67,586,653
Ensembl chr11:67,583,742...67,586,656
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H19
H19 imprinted maternally expressed transcript
decreases expression
ISO
Zearalenone results in decreased expression of H19 mRNA
CTD
PMID:17557909
NCBI chr11:1,995,176...2,001,266
Ensembl chr11:1,995,165...2,004,552
G
H2AX
H2A.X variant histone
increases expression decreases expression
ISO
Zearalenone results in increased expression of H2AX protein modified form Zearalenone results in decreased expression of H2AX protein
CTD
PMID:28089945 PMID:28552778 PMID:35504548 PMID:35650142
NCBI chr11:119,093,874...119,095,465
Ensembl chr11:119,093,874...119,095,465
G
H2BC5
H2B clustered histone 5
decreases expression
EXP
Zearalenone results in decreased expression of H2BC5 mRNA
CTD
PMID:19371625
NCBI chr 6:26,158,121...26,171,349
Ensembl chr 6:26,158,122...26,171,349
G
HADHB
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta
decreases expression
ISO
Zearalenone results in decreased expression of HADHB mRNA; Zearalenone results in decreased expression of HADHB protein
CTD
PMID:32858132
NCBI chr 2:26,244,939...26,290,465
Ensembl chr 2:26,243,170...26,290,465
G
HAPLN3
hyaluronan and proteoglycan link protein 3
decreases expression
EXP
Zearalenone results in decreased expression of HAPLN3 mRNA
CTD
PMID:19371625
NCBI chr15:88,877,294...88,895,544
Ensembl chr15:88,877,294...88,895,597
G
HAT1
histone acetyltransferase 1
increases expression
EXP
Zearalenone results in increased expression of HAT1 mRNA
CTD
PMID:32119988
NCBI chr 2:171,922,461...171,983,686
Ensembl chr 2:171,922,448...171,983,686
G
HBB
hemoglobin subunit beta
decreases expression
ISO
Zearalenone results in decreased expression of HBB mRNA
CTD
PMID:17557909
NCBI chr11:5,225,464...5,227,071
Ensembl chr11:5,225,464...5,229,395
G
HERPUD1
homocysteine inducible ER protein with ubiquitin like domain 1
multiple interactions increases expression
ISO
4-phenylbutylamine promotes the reaction [Zearalenone results in increased expression of HERPUD1 protein]; HERPUD1 protein inhibits the reaction [Zearalenone results in decreased phosphorylation of RPS6KB1 protein]; HERPUD1 protein promotes the reaction [Zearalenone results in decreased phosphorylation of MAPK1 protein]; HERPUD1 protein promotes the reaction [Zearalenone results in decreased phosphorylation of MAPK3 protein]; HERPUD1 protein promotes the reaction [Zearalenone results in increased expression of CASP3 protein modified form]
CTD
PMID:30394307
NCBI chr16:56,932,142...56,944,864
Ensembl chr16:56,932,142...56,944,864
G
HES2
hes family bHLH transcription factor 2
increases expression
EXP
Zearalenone results in increased expression of HES2 mRNA
CTD
PMID:19371625
NCBI chr 1:6,415,232...6,419,919
Ensembl chr 1:6,412,418...6,424,670
G
HIVEP1
HIVEP zinc finger 1
increases expression
EXP
Zearalenone results in increased expression of HIVEP1 mRNA
CTD
PMID:19371625
NCBI chr 6:12,007,693...12,212,048
Ensembl chr 6:12,008,762...12,164,999
G
HK2
hexokinase 2
increases expression
EXP
Zearalenone results in increased expression of HK2 mRNA
CTD
PMID:32119988
NCBI chr 2:74,834,127...74,893,359
Ensembl chr 2:74,834,127...74,893,359
G
HMGCS1
3-hydroxy-3-methylglutaryl-CoA synthase 1
decreases expression
EXP
Zearalenone results in decreased expression of HMGCS1 mRNA
CTD
PMID:25424538
NCBI chr 5:43,287,470...43,313,412
Ensembl chr 5:43,287,470...43,313,512
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HMGN2
high mobility group nucleosomal binding domain 2
decreases expression
EXP
Zearalenone results in decreased expression of HMGN2 mRNA
CTD
PMID:19371625
NCBI chr 1:26,472,440...26,476,642
Ensembl chr 1:26,472,440...26,478,209
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HMOX1
heme oxygenase 1
increases expression multiple interactions
ISO
Zearalenone results in increased expression of HMOX1 protein 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [corynoline promotes the reaction [Zearalenone results in increased expression of HMOX1 protein]]; corynoline promotes the reaction [Zearalenone results in increased expression of HMOX1 protein]
CTD
PMID:36161741
NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214
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HNF4A
hepatocyte nuclear factor 4 alpha
multiple interactions
EXP
[deoxynivalenol co-treated with Zearalenone] affects the expression of HNF4A mRNA
CTD
PMID:28865950
NCBI chr20:44,355,699...44,434,596
Ensembl chr20:44,355,699...44,432,845
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HOXA10
homeobox A10
decreases expression
ISO
Zearalenone results in decreased expression of HOXA10 mRNA
CTD
PMID:27862621
NCBI chr 7:27,170,605...27,179,861
Ensembl chr 7:27,170,605...27,180,261
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HPDL
4-hydroxyphenylpyruvate dioxygenase like
increases expression
EXP
Zearalenone results in increased expression of HPDL mRNA
CTD
PMID:36828454
NCBI chr 1:45,326,895...45,328,710
Ensembl chr 1:45,326,895...45,328,710
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HRAS
HRas proto-oncogene, GTPase
decreases expression
ISO
Zearalenone results in decreased expression of HRAS mRNA
CTD
PMID:30717214
NCBI chr11:532,242...535,576
Ensembl chr11:532,242...537,321
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HSD11B1
hydroxysteroid 11-beta dehydrogenase 1
decreases expression
ISO
Zearalenone results in decreased expression of HSD11B1 mRNA; Zearalenone results in decreased expression of HSD11B1 protein
CTD
PMID:29669061
NCBI chr 1:209,686,179...209,734,929
Ensembl chr 1:209,686,178...209,734,949
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HSD17B1
hydroxysteroid 17-beta dehydrogenase 1
decreases expression
ISO
Zearalenone results in decreased expression of HSD17B1 protein
CTD
PMID:31419471
NCBI chr17:42,552,923...42,555,214
Ensembl chr17:42,552,922...42,555,214
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HSD17B11
hydroxysteroid 17-beta dehydrogenase 11
multiple interactions
ISO
[Zearalenone co-treated with CGA protein] results in decreased expression of HSD17B11 protein
CTD
PMID:25058043
NCBI chr 4:87,336,515...87,391,188
Ensembl chr 4:87,336,515...87,391,188
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HSD17B14
hydroxysteroid 17-beta dehydrogenase 14
decreases expression
EXP
Zearalenone results in decreased expression of HSD17B14 mRNA
CTD
PMID:19371625
NCBI chr19:48,813,018...48,836,491
Ensembl chr19:48,813,018...48,836,510
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HSD17B2
hydroxysteroid 17-beta dehydrogenase 2
increases expression
ISO
Zearalenone results in increased expression of HSD17B2 mRNA
CTD
PMID:20607812
NCBI chr16:82,035,253...82,098,534
Ensembl chr16:82,035,004...82,098,534
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HSD17B3
hydroxysteroid 17-beta dehydrogenase 3
decreases expression decreases activity
ISO
Zearalenone results in decreased expression of HSD17B3 mRNA Zearalenone results in decreased activity of HSD17B3 protein Zearalenone results in decreased expression of HSD17B3 mRNA; Zearalenone results in decreased expression of HSD17B3 protein
CTD
PMID:24512812 PMID:29669061
NCBI chr 9:96,235,306...96,302,176
Ensembl chr 9:96,235,306...96,302,176
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HSD17B4
hydroxysteroid 17-beta dehydrogenase 4
decreases expression
ISO
Zearalenone results in decreased expression of HSD17B4 protein
CTD
PMID:31419471
NCBI chr 5:119,452,497...119,542,332
Ensembl chr 5:119,452,465...119,637,199
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HSD3B1
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
decreases expression decreases activity
ISO
Zearalenone results in decreased expression of HSD3B1 mRNA Zearalenone results in decreased activity of HSD3B1 protein
CTD
PMID:24512812 PMID:29669061
NCBI chr 1:119,507,203...119,515,058
Ensembl chr 1:119,507,198...119,515,054
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HSD3B2
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
affects expression
ISO
Zearalenone affects the expression of HSD3B2 mRNA
CTD
PMID:29627501
NCBI chr 1:119,414,931...119,423,034
Ensembl chr 1:119,414,931...119,423,035
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HSP90AB1
heat shock protein 90 alpha family class B member 1
decreases expression
ISO
Zearalenone results in decreased expression of HSP90AB1 protein
CTD
PMID:36252740
NCBI chr 6:44,246,194...44,253,883
Ensembl chr 6:44,246,166...44,253,888
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HSPA1A
heat shock protein family A (Hsp70) member 1A
increases expression decreases expression
EXP ISO
Zearalenone results in increased expression of HSPA1A mRNA; Zearalenone results in increased expression of HSPA1A protein Zearalenone results in decreased expression of HSPA1A protein
CTD
PMID:19051279 PMID:36252740
NCBI chr 6:31,815,543...31,817,942
Ensembl chr 6:31,815,543...31,817,946
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HSPA1B
heat shock protein family A (Hsp70) member 1B
increases expression
EXP ISO
Zearalenone results in increased expression of HSPA1B mRNA
CTD
PMID:25424538 PMID:27862621
NCBI chr 6:31,827,738...31,830,254
Ensembl chr 6:31,827,738...31,830,254
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HSPA4
heat shock protein family A (Hsp70) member 4
decreases expression
ISO
Zearalenone results in decreased expression of HSPA4 protein
CTD
PMID:25058043
NCBI chr 5:133,052,013...133,106,449
Ensembl chr 5:133,052,013...133,106,449
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HSPA5
heat shock protein family A (Hsp70) member 5
increases expression multiple interactions
ISO
Zearalenone results in increased expression of HSPA5 protein 2-aminoethyl diphenylborinate inhibits the reaction [Zearalenone results in increased expression of HSPA5 protein]; 4-phenylbutylamine promotes the reaction [Zearalenone results in increased expression of HSPA5 protein]
CTD
PMID:30394307 PMID:31982503
NCBI chr 9:125,234,853...125,241,343
Ensembl chr 9:125,234,853...125,241,382
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HSPB1
heat shock protein family B (small) member 1
increases expression
EXP
Zearalenone results in increased expression of HSPB1 protein
CTD
PMID:19051279
NCBI chr 7:76,302,673...76,304,292
Ensembl chr 7:76,302,673...76,305,813
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HSPB8
heat shock protein family B (small) member 8
decreases expression
ISO
Zearalenone results in decreased expression of HSPB8 protein
CTD
PMID:36252740
NCBI chr12:119,178,931...119,194,746
Ensembl chr12:119,171,555...119,224,855
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HSPH1
heat shock protein family H (Hsp110) member 1
decreases expression
ISO
Zearalenone results in decreased expression of HSPH1 protein
CTD
PMID:36252740
NCBI chr13:31,134,973...31,162,388
Ensembl chr13:31,134,973...31,162,388
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ID1
inhibitor of DNA binding 1
decreases expression
EXP
Zearalenone results in decreased expression of ID1 mRNA
CTD
PMID:25424538
NCBI chr20:31,605,289...31,606,510
Ensembl chr20:31,573,014...31,606,515
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ID2
inhibitor of DNA binding 2
multiple interactions increases expression
ISO
[Tamoxifen co-treated with Zearalenone] results in increased expression of ID2 mRNA Zearalenone results in increased expression of ID2 mRNA
CTD
PMID:30138655
NCBI chr 2:8,682,056...8,684,461
Ensembl chr 2:8,678,845...8,684,461
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IDH3A
isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha
increases expression
ISO
Zearalenone results in increased expression of IDH3A protein
CTD
PMID:25058043
NCBI chr15:78,149,362...78,171,945
Ensembl chr15:78,131,498...78,171,945
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IDO1
indoleamine 2,3-dioxygenase 1
decreases expression
EXP
Zearalenone results in decreased expression of IDO1 mRNA
CTD
PMID:36828454
NCBI chr 8:39,913,891...39,928,790
Ensembl chr 8:39,902,275...39,928,790
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IFITM3
interferon induced transmembrane protein 3
decreases expression
EXP
Zearalenone results in decreased expression of IFITM3 mRNA
CTD
PMID:19371625
NCBI chr11:319,676...320,860
Ensembl chr11:319,676...329,475
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IGF1
insulin like growth factor 1
increases expression decreases expression
EXP
Zearalenone results in increased expression of IGF1 mRNA Zearalenone results in decreased expression of IGF1 mRNA
CTD
PMID:27757495 PMID:28965971
NCBI chr12:102,395,874...102,481,839
Ensembl chr12:102,395,874...102,481,744
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IGFBP3
insulin like growth factor binding protein 3
decreases expression
EXP
Zearalenone results in decreased expression of IGFBP3 mRNA
CTD
PMID:28965971 PMID:36828454
NCBI chr 7:45,912,245...45,921,272
Ensembl chr 7:45,912,245...45,921,874
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IGFBP6
insulin like growth factor binding protein 6
decreases expression
EXP
Zearalenone results in decreased expression of IGFBP6 mRNA
CTD
PMID:19371625
NCBI chr12:53,097,667...53,102,340
Ensembl chr12:53,097,436...53,102,345
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IGSF9
immunoglobulin superfamily member 9
decreases expression
EXP
Zearalenone results in decreased expression of IGSF9 mRNA
CTD
PMID:36828454
NCBI chr 1:159,927,041...159,945,613
Ensembl chr 1:159,927,039...159,945,613
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IKBKG
inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
increases expression
ISO
Zearalenone results in increased expression of IKBKG mRNA
CTD
PMID:39053873
NCBI chr X:154,541,238...154,565,046
Ensembl chr X:154,541,199...154,565,046
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IKZF2
IKAROS family zinc finger 2
decreases expression
EXP
Zearalenone results in decreased expression of IKZF2 mRNA
CTD
PMID:36828454
NCBI chr 2:212,999,698...213,152,456
Ensembl chr 2:212,999,691...213,152,427
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IL10
interleukin 10
multiple interactions increases expression
ISO
lycopene inhibits the reaction [Zearalenone results in increased expression of IL10]
CTD
PMID:25682699
NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541
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IL12A
interleukin 12A
increases expression
EXP
Zearalenone results in increased expression of IL12A mRNA
CTD
PMID:36828454
NCBI chr 3:159,988,835...159,996,019
Ensembl chr 3:159,988,835...159,996,019
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IL13
interleukin 13
increases expression
EXP
Zearalenone results in increased expression of IL13 mRNA
CTD
PMID:27757495
NCBI chr 5:132,656,522...132,661,110
Ensembl chr 5:132,656,263...132,661,110
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IL18
interleukin 18
increases expression increases secretion multiple interactions
ISO
Zearalenone results in increased expression of IL18 mRNA Zearalenone results in increased secretion of IL18 protein [Dextran Sulfate co-treated with Zearalenone] results in increased expression of IL18 mRNA; [Dextran Sulfate co-treated with Zearalenone] results in increased secretion of IL18 protein; Dextran Sulfate inhibits the reaction [Zearalenone results in increased secretion of IL18 protein]; Nicotinamide Mononucleotide inhibits the reaction [Zearalenone results in increased expression of IL18 mRNA]; Zearalenone inhibits the reaction [Dextran Sulfate results in increased expression of IL18 mRNA]; Zearalenone inhibits the reaction [Dextran Sulfate results in increased secretion of IL18 protein]
CTD
PMID:30270565 PMID:38159578
NCBI chr11:112,143,260...112,164,094
Ensembl chr11:112,143,251...112,164,096
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IL1B
interleukin 1 beta
multiple interactions increases expression increases secretion
ISO EXP
6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [corynoline inhibits the reaction [Zearalenone results in increased expression of IL1B protein]]; [Dextran Sulfate co-treated with Zearalenone] results in increased secretion of IL1B protein; [Rutin co-treated with Zearalenone] results in increased expression of IL1B mRNA; corynoline inhibits the reaction [Zearalenone results in increased expression of IL1B protein]; Lipopolysaccharides promotes the reaction [Zearalenone results in increased expression of IL1B mRNA]; Lycopene inhibits the reaction [Zearalenone results in increased expression of IL1B]; Nicotinamide Mononucleotide inhibits the reaction [Zearalenone results in increased expression of IL1B mRNA]; Rutin inhibits the reaction [Zearalenone results in increased expression of IL1B protein]; Zearalenone inhibits the reaction [Dextran Sulfate results in increased secretion of IL1B protein] Zearalenone results in increased expression of IL1B; Zearalenone results in increased expression of IL1B mRNA; Zearalenone results in increased expression of IL1B protein Zearalenone results in increased secretion of IL1B protein 3-methyladenine promotes the reaction [[Zearalenone co-treated with Lipopolysaccharides] results in increased expression of IL1B protein modified form]; [Zearalenone co-treated with Lipopolysaccharides] results in increased expression of IL1B mRNA; [Zearalenone co-treated with Lipopolysaccharides] results in increased expression of IL1B protein; [Zearalenone co-treated with Lipopolysaccharides] results in increased expression of IL1B protein modified form; N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide inhibits the reaction [[Zearalenone co-treated with Lipopolysaccharides] results in increased expression of IL1B mRNA]; N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide inhibits the reaction [[Zearalenone co-treated with Lipopolysaccharides] results in increased expression of IL1B protein modified form]; NLRP3 protein promotes the reaction [[Zearalenone co-treated with Lipopolysaccharides] results in increased expression of IL1B protein modified form]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Zearalenone co-treated with Lipopolysaccharides] results in increased expression of IL1B mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Zearalenone results in increased expression of IL1B protein modified form]; Sirolimus inhibits the reaction [[Zearalenone co-treated with Lipopolysaccharides] results in increased expression of IL1B protein modified form] [Zearalenone co-treated with deoxynivalenol] results in increased expression of IL1B mRNA
CTD
PMID:16687389 PMID:25682699 PMID:30270565 PMID:31586597 PMID:35090964 PMID:36161741 PMID:38159578 PMID:39053873 More...
NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816
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IL1RN
interleukin 1 receptor antagonist
decreases expression
EXP
Zearalenone results in decreased expression of IL1RN mRNA
CTD
PMID:36828454
NCBI chr 2:113,099,360...113,134,014
Ensembl chr 2:113,099,315...113,134,016
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IL2
interleukin 2
multiple interactions increases expression
ISO
lycopene inhibits the reaction [Zearalenone results in increased expression of IL2]
CTD
PMID:25682699
NCBI chr 4:122,451,470...122,456,725
Ensembl chr 4:122,451,470...122,456,725
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IL4
interleukin 4
increases expression
EXP
Zearalenone results in increased expression of IL4 mRNA
CTD
PMID:27757495
NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678
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IL4R
interleukin 4 receptor
increases expression
EXP
Zearalenone results in increased expression of IL4R mRNA
CTD
PMID:19371625
NCBI chr16:27,313,756...27,364,778
Ensembl chr16:27,313,668...27,364,778
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IL6
interleukin 6
multiple interactions increases expression
ISO EXP
Lipopolysaccharides promotes the reaction [Zearalenone results in increased expression of IL6 mRNA]; Lycopene inhibits the reaction [Zearalenone results in increased expression of IL6]; Rutin inhibits the reaction [Zearalenone results in increased expression of IL6 mRNA]; Rutin inhibits the reaction [Zearalenone results in increased expression of IL6 protein] Zearalenone results in increased expression of IL6; Zearalenone results in increased expression of IL6 mRNA; Zearalenone results in increased expression of IL6 protein [Lipopolysaccharides co-treated with Zearalenone] results in increased secretion of IL6 protein; [Zearalenone co-treated with Aflatoxin B1] results in decreased expression of IL6 mRNA; [Zearalenone co-treated with deoxynivalenol] results in increased expression of IL6 mRNA
CTD
PMID:16687389 PMID:25682699 PMID:28965971 PMID:32328699 PMID:35090964 PMID:39053873 More...
NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002
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IMMT
inner membrane mitochondrial protein
increases expression
ISO
Zearalenone results in increased expression of IMMT protein
CTD
PMID:25058043
NCBI chr 2:86,143,936...86,195,462
Ensembl chr 2:86,143,932...86,195,472
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IMPDH2
inosine monophosphate dehydrogenase 2
increases expression
EXP
Zearalenone results in increased expression of IMPDH2 mRNA
CTD
PMID:19371625
NCBI chr 3:49,024,325...49,029,398
Ensembl chr 3:49,024,325...49,029,447
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INHBA
inhibin subunit beta A
decreases expression
ISO
Zearalenone results in decreased expression of INHBA mRNA
CTD
PMID:30138655
NCBI chr 7:41,685,114...41,705,406
Ensembl chr 7:41,667,168...41,705,834
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IPO13
importin 13
increases expression
EXP
Zearalenone results in increased expression of IPO13 mRNA
CTD
PMID:19371625
NCBI chr 1:43,946,950...43,968,022
Ensembl chr 1:43,946,950...43,968,022
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ISM1
isthmin 1
increases expression
EXP
Zearalenone results in increased expression of ISM1 mRNA
CTD
PMID:36828454
NCBI chr20:13,221,274...13,326,723
Ensembl chr20:13,221,274...13,300,651
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ISYNA1
inositol-3-phosphate synthase 1
decreases expression
ISO
Zearalenone results in decreased expression of ISYNA1 protein
CTD
PMID:36252740
NCBI chr19:18,434,388...18,438,133
Ensembl chr19:18,434,388...18,438,167
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ITPK1
inositol-tetrakisphosphate 1-kinase
increases expression
EXP
Zearalenone results in increased expression of ITPK1 mRNA
CTD
PMID:19371625
NCBI chr14:92,936,914...93,115,925
Ensembl chr14:92,936,914...93,116,320
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JAG1
jagged canonical Notch ligand 1
increases expression
ISO
Zearalenone results in increased expression of JAG1 mRNA
CTD
PMID:30138655 PMID:32858132
NCBI chr20:10,637,684...10,673,999
Ensembl chr20:10,637,684...10,673,999
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JUN
Jun proto-oncogene, AP-1 transcription factor subunit
multiple interactions increases expression
ISO
scutellarin inhibits the reaction [Zearalenone results in increased expression of JUN protein]
CTD
PMID:27473017 PMID:36252740
NCBI chr 1:58,780,791...58,784,047
Ensembl chr 1:58,776,845...58,784,048
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KAT2B
lysine acetyltransferase 2B
increases expression
EXP
Zearalenone results in increased expression of KAT2B mRNA
CTD
PMID:32119988
NCBI chr 3:20,040,446...20,154,404
Ensembl chr 3:20,040,446...20,154,404
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KAZN
kazrin, periplakin interacting protein
increases expression
EXP
Zearalenone results in increased expression of KAZN mRNA
CTD
PMID:36828454
NCBI chr 1:13,892,824...15,118,043
Ensembl chr 1:13,892,792...15,118,043
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KBTBD8
kelch repeat and BTB domain containing 8
increases expression
EXP
Zearalenone results in increased expression of KBTBD8 mRNA
CTD
PMID:36828454
NCBI chr 3:66,998,307...67,011,210
Ensembl chr 3:66,998,307...67,011,210
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KCNF1
potassium voltage-gated channel modifier subfamily F member 1
increases expression
EXP
Zearalenone results in increased expression of KCNF1 mRNA
CTD
PMID:19371625 PMID:36828454
NCBI chr 2:10,911,934...10,914,225
Ensembl chr 2:10,911,934...10,914,225
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KCNJ2
potassium inwardly rectifying channel subfamily J member 2
increases expression
EXP
Zearalenone results in increased expression of KCNJ2 mRNA
CTD
PMID:36828454
NCBI chr17:70,169,532...70,180,044
Ensembl chr17:70,168,673...70,180,044
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KCNJ5
potassium inwardly rectifying channel subfamily J member 5
increases expression
EXP
Zearalenone results in increased expression of KCNJ5 mRNA
CTD
PMID:19371625
NCBI chr11:128,891,356...128,921,163
Ensembl chr11:128,891,356...128,921,163
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KCNK15
potassium two pore domain channel subfamily K member 15
increases expression
EXP
Zearalenone results in increased expression of KCNK15 mRNA
CTD
PMID:36828454
NCBI chr20:44,745,865...44,752,313
Ensembl chr20:44,745,865...44,752,313
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KCTD20
potassium channel tetramerization domain containing 20
increases expression
EXP
Zearalenone results in increased expression of KCTD20 mRNA
CTD
PMID:19371625
NCBI chr 6:36,443,000...36,491,141
Ensembl chr 6:36,442,767...36,491,143
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KDM4A
lysine demethylase 4A
decreases expression
ISO
Zearalenone results in decreased expression of KDM4A mRNA
CTD
PMID:24412631
NCBI chr 1:43,650,149...43,705,518
Ensembl chr 1:43,650,149...43,705,518
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KDM4A-AS1
KDM4A antisense RNA 1
increases expression
EXP
Zearalenone results in increased expression of KDM4A-AS1 mRNA
CTD
PMID:36828454
NCBI chr 1:43,699,724...43,707,341
Ensembl chr 1:43,685,123...43,708,138
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KITLG
KIT ligand
decreases expression
EXP
Zearalenone results in decreased expression of KITLG mRNA
CTD
PMID:27757495
NCBI chr12:88,492,793...88,580,471
Ensembl chr12:88,492,793...88,580,851
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KMT5A
lysine methyltransferase 5A
increases expression
EXP
Zearalenone results in increased expression of KMT5A mRNA
CTD
PMID:32119988
NCBI chr12:123,384,132...123,409,353
Ensembl chr12:123,384,132...123,409,353
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KRAS
KRAS proto-oncogene, GTPase
increases expression decreases expression
ISO
Zearalenone results in increased expression of KRAS mRNA Zearalenone results in decreased expression of KRAS mRNA
CTD
PMID:29758222 PMID:30717214
NCBI chr12:25,205,246...25,250,929
Ensembl chr12:25,205,246...25,250,936
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KRT10
keratin 10
decreases expression
ISO
Zearalenone results in decreased expression of KRT10 protein
CTD
PMID:25058043
NCBI chr17:40,818,117...40,822,614
Ensembl chr17:40,818,117...40,822,614
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KRT17
keratin 17
decreases expression
EXP
Zearalenone results in decreased expression of KRT17 mRNA
CTD
PMID:19371625
NCBI chr17:41,619,442...41,624,575
Ensembl chr17:41,619,442...41,624,842
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KRT4
keratin 4
decreases expression
EXP
Zearalenone results in decreased expression of KRT4 mRNA
CTD
PMID:36828454
NCBI chr12:52,806,549...52,814,116
Ensembl chr12:52,806,549...52,814,116
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KRT5
keratin 5
increases expression
EXP
Zearalenone results in increased expression of KRT5 mRNA
CTD
PMID:28965971
NCBI chr12:52,514,575...52,520,394
Ensembl chr12:52,514,575...52,520,530
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KRT7
keratin 7
increases expression
ISO
Zearalenone results in increased expression of KRT7 mRNA
CTD
PMID:17557909
NCBI chr12:52,233,243...52,255,853
Ensembl chr12:52,232,520...52,252,186
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KRTAP2-3
keratin associated protein 2-3
decreases expression
EXP
Zearalenone results in decreased expression of KRTAP2-3 mRNA
CTD
PMID:36828454
NCBI chr17:41,059,240...41,060,114
Ensembl chr17:41,059,240...41,060,114
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LDLR
low density lipoprotein receptor
increases expression decreases expression
EXP ISO
Zearalenone results in increased expression of LDLR mRNA Zearalenone results in decreased expression of LDLR mRNA; Zearalenone results in decreased expression of LDLR protein
CTD
PMID:32119988 PMID:32858132
NCBI chr19:11,089,463...11,133,820
Ensembl chr19:11,089,418...11,133,820
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LEFTY2
left-right determination factor 2
decreases expression
EXP
Zearalenone results in decreased expression of LEFTY2 mRNA
CTD
PMID:19371625
NCBI chr 1:225,936,603...225,941,220
Ensembl chr 1:225,936,598...225,941,383
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LGALS1
galectin 1
decreases expression
EXP
Zearalenone results in decreased expression of LGALS1 mRNA
CTD
PMID:19371625
NCBI chr22:37,675,636...37,679,802
Ensembl chr22:37,675,636...37,679,802
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LHB
luteinizing hormone subunit beta
decreases expression multiple interactions
ISO
Zearalenone results in decreased expression of LHB protein Gallic Acid inhibits the reaction [Zearalenone results in decreased expression of LHB protein]
CTD
PMID:29627501 PMID:32858132 PMID:34723416
NCBI chr19:49,015,980...49,019,498
Ensembl chr19:49,015,980...49,017,091
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LHCGR
luteinizing hormone/choriogonadotropin receptor
multiple interactions
ISO
[Colforsin co-treated with Zearalenone] results in increased expression of LHCGR mRNA
CTD
PMID:26783879
NCBI chr 2:48,686,774...48,755,724
Ensembl chr 2:48,686,774...48,755,730
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LHX8
LIM homeobox 8
decreases expression
ISO
Zearalenone results in decreased expression of LHX8 mRNA; Zearalenone results in decreased expression of LHX8 protein
CTD
PMID:28089945
NCBI chr 1:75,128,434...75,199,454
Ensembl chr 1:75,128,434...75,161,533
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LINC01133
long intergenic non-protein coding RNA 1133
decreases expression
EXP
Zearalenone results in decreased expression of LINC01133 mRNA
CTD
PMID:36828454
NCBI chr 1:159,961,224...159,979,086
Ensembl chr 1:159,941,373...160,025,027
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LINC01559
long intergenic non-protein coding RNA 1559
decreases expression
EXP
Zearalenone results in decreased expression of LINC01559 mRNA
CTD
PMID:36828454
NCBI chr12:13,370,671...13,376,745
Ensembl chr12:13,371,089...13,387,167
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LMNA
lamin A/C
increases expression
ISO
Zearalenone results in increased expression of LMNA protein
CTD
PMID:36252740
NCBI chr 1:156,082,573...156,140,081
Ensembl chr 1:156,082,572...156,140,081
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LMNB1
lamin B1
increases expression
ISO
Zearalenone results in increased expression of LMNB1 protein
CTD
PMID:36252740
NCBI chr 5:126,776,623...126,837,020
Ensembl chr 5:126,776,623...126,837,020
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LONRF2
LON peptidase N-terminal domain and ring finger 2
increases expression
EXP
Zearalenone results in increased expression of LONRF2 mRNA
CTD
PMID:36828454
NCBI chr 2:100,271,875...100,322,501
Ensembl chr 2:100,271,875...100,322,501
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LPAL2
lipoprotein(a) like 2 (pseudogene)
increases expression
EXP
Zearalenone results in increased expression of LPAL2 mRNA
CTD
PMID:36828454
NCBI chr 6:160,466,555...160,511,124
Ensembl chr 6:160,453,428...160,511,007 Ensembl chr 6:160,453,428...160,511,007
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LPIN1
lipin 1
multiple interactions increases expression
ISO
Nicotinamide Mononucleotide inhibits the reaction [Zearalenone results in increased expression of LPIN1 protein]
CTD
PMID:38159578
NCBI chr 2:11,677,544...11,827,409
Ensembl chr 2:11,677,595...11,827,409
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LRRC4
leucine rich repeat containing 4
decreases expression
EXP
Zearalenone results in decreased expression of LRRC4 mRNA
CTD
PMID:36828454
NCBI chr 7:128,027,071...128,032,128
Ensembl chr 7:128,027,071...128,032,107
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LSP1
lymphocyte specific protein 1
decreases expression
ISO
Zearalenone results in decreased expression of LSP1 mRNA
CTD
PMID:17557909
NCBI chr11:1,853,084...1,892,263
Ensembl chr11:1,850,904...1,892,267
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LYAR
Ly1 antibody reactive
increases expression
EXP
Zearalenone results in increased expression of LYAR mRNA
CTD
PMID:36828454
NCBI chr 4:4,267,701...4,290,154
Ensembl chr 4:4,267,701...4,290,154
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MAK16
MAK16 homolog
increases expression
EXP
Zearalenone results in increased expression of RBM13 mRNA
CTD
PMID:19371625
NCBI chr 8:33,485,182...33,501,262
Ensembl chr 8:33,485,182...33,501,262
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MAP1LC3A
microtubule associated protein 1 light chain 3 alpha
increases expression
ISO
Zearalenone results in increased expression of MAP1LC3A mRNA
CTD
PMID:34537261
NCBI chr20:34,546,844...34,560,345
Ensembl chr20:34,546,854...34,560,345
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MAP1LC3B
microtubule associated protein 1 light chain 3 beta
increases expression
ISO
Zearalenone results in increased expression of MAP1LC3B protein
CTD
PMID:31586597 PMID:32858132 PMID:34537261
NCBI chr16:87,392,336...87,404,774
Ensembl chr16:87,383,953...87,404,779
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MAP2K1
mitogen-activated protein kinase kinase 1
decreases expression
ISO
Zearalenone results in decreased expression of MAP2K1 protein
CTD
PMID:36252740
NCBI chr15:66,386,912...66,491,544
Ensembl chr15:66,386,837...66,491,656
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MAP2K4
mitogen-activated protein kinase kinase 4
multiple interactions increases expression decreases expression
ISO
scutellarin inhibits the reaction [Zearalenone results in increased expression of MAP2K4 protein] Zearalenone results in decreased expression of MAP2K4 protein
CTD
PMID:36252740
NCBI chr17:12,020,877...12,143,828
Ensembl chr17:12,020,829...12,143,830
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MAPK1
mitogen-activated protein kinase 1
multiple interactions decreases phosphorylation increases phosphorylation
ISO
HERPUD1 protein promotes the reaction [Zearalenone results in decreased phosphorylation of MAPK1 protein]; Nicotinamide Mononucleotide inhibits the reaction [Zearalenone results in increased phosphorylation of MAPK1 protein]; Zearalenone results in decreased expression of and results in decreased phosphorylation of MAPK1 protein
CTD
PMID:30394307 PMID:32858132 PMID:34716709 PMID:38159578
NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680
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MAPK13
mitogen-activated protein kinase 13
decreases expression
EXP
Zearalenone results in decreased expression of MAPK13 mRNA
CTD
PMID:19371625
NCBI chr 6:36,130,513...36,144,521
Ensembl chr 6:36,127,809...36,144,524
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MAPK3
mitogen-activated protein kinase 3
decreases phosphorylation multiple interactions increases phosphorylation
ISO
Zearalenone results in decreased phosphorylation of MAPK3 protein HERPUD1 protein promotes the reaction [Zearalenone results in decreased phosphorylation of MAPK3 protein]; Nicotinamide Mononucleotide inhibits the reaction [Zearalenone results in increased phosphorylation of MAPK3 protein]
CTD
PMID:30394307 PMID:32858132 PMID:38159578
NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506
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MAPK8
mitogen-activated protein kinase 8
increases phosphorylation increases expression
ISO
Zearalenone results in increased phosphorylation of MAPK8 protein Zearalenone results in increased expression of MAPK8 mRNA
CTD
PMID:21767629 PMID:30717214
NCBI chr10:48,306,677...48,439,360
Ensembl chr10:48,306,639...48,439,360
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MAS1
MAS1 proto-oncogene, G protein-coupled receptor
increases expression
ISO
Zearalenone results in increased expression of MAS1 mRNA
CTD
PMID:24412631
NCBI chr 6:159,888,787...159,917,447
Ensembl chr 6:159,890,988...159,917,447
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MAT2B
methionine adenosyltransferase 2 non-catalytic beta subunit
decreases expression
ISO
Zearalenone results in decreased expression of MAT2B protein
CTD
PMID:36252740
NCBI chr 5:163,503,064...163,519,354
Ensembl chr 5:163,503,114...163,519,558
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MDH2
malate dehydrogenase 2
increases expression
ISO
Zearalenone results in increased expression of MDH2 protein
CTD
PMID:25058043
NCBI chr 7:76,048,106...76,067,508
Ensembl chr 7:76,048,051...76,067,508
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MDK
midkine
decreases expression
EXP
Zearalenone results in decreased expression of MDK mRNA
CTD
PMID:19371625
NCBI chr11:46,380,784...46,383,837
Ensembl chr11:46,380,756...46,383,837
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MEOX1
mesenchyme homeobox 1
decreases expression
EXP
Zearalenone results in decreased expression of MEOX1 mRNA
CTD
PMID:19371625
NCBI chr17:43,640,389...43,661,922
Ensembl chr17:43,640,389...43,661,922
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MET
MET proto-oncogene, receptor tyrosine kinase
increases expression
EXP
Zearalenone results in increased expression of MET mRNA
CTD
PMID:19371625
NCBI chr 7:116,672,196...116,798,377
Ensembl chr 7:116,672,196...116,798,377
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MFAP2
microfibril associated protein 2
decreases expression
EXP
Zearalenone results in decreased expression of MFAP2 mRNA
CTD
PMID:36828454
NCBI chr 1:16,974,502...16,981,583
Ensembl chr 1:16,974,502...16,980,632
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MFGE8
milk fat globule EGF and factor V/VIII domain containing
decreases expression
EXP
Zearalenone results in decreased expression of MFGE8 mRNA
CTD
PMID:19371625
NCBI chr15:88,898,683...88,913,379
Ensembl chr15:88,898,683...88,913,468
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MFN2
mitofusin 2
increases expression
EXP
Zearalenone results in increased expression of MFN2 mRNA
CTD
PMID:19371625
NCBI chr 1:11,980,444...12,013,508
Ensembl chr 1:11,980,181...12,015,211
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MGAT3
beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase
increases expression
EXP
Zearalenone results in increased expression of MGAT3 mRNA
CTD
PMID:36828454
NCBI chr22:39,457,012...39,492,194
Ensembl chr22:39,457,012...39,492,194
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MGLL
monoglyceride lipase
multiple interactions
ISO
[Zearalenone co-treated with CGA protein] results in decreased expression of MGLL protein
CTD
PMID:25058043
NCBI chr 3:127,689,066...127,823,185
Ensembl chr 3:127,689,062...128,052,190
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MICA
MHC class I polypeptide-related sequence A
increases expression
EXP
Zearalenone results in increased expression of MICA mRNA
CTD
PMID:27757495
NCBI chr 6:31,400,711...31,415,315
Ensembl chr 6:31,399,784...31,415,315
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MIR146B
microRNA 146b
decreases expression
ISO
Zearalenone results in decreased expression of MIR146B mRNA
CTD
PMID:30717214
NCBI chr10:102,436,512...102,436,584
Ensembl chr10:102,436,512...102,436,584
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MIR185
microRNA 185
decreases expression
ISO
Zearalenone results in decreased expression of MIR185 mRNA
CTD
PMID:30717214
NCBI chr22:20,033,139...20,033,220
Ensembl chr22:20,033,139...20,033,220
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MIR197
microRNA 197
decreases expression
EXP
Zearalenone results in decreased expression of MIR197 mRNA
CTD
PMID:36828454
NCBI chr 1:109,598,893...109,598,967
Ensembl chr 1:109,598,893...109,598,967
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MIR19A
microRNA 19a
increases expression
ISO
Zearalenone results in increased expression of MIR19A mRNA
CTD
PMID:30717214
NCBI chr13:91,350,891...91,350,972
Ensembl chr13:91,350,891...91,350,972
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MIR200A
microRNA 200a
multiple interactions
EXP
Zearalenone results in decreased expression of and affects the secretion of MIR200A mRNA
CTD
PMID:33419253
NCBI chr 1:1,167,863...1,167,952
Ensembl chr 1:1,167,863...1,167,952
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MIR200B
microRNA 200b
multiple interactions
EXP
Zearalenone results in decreased expression of and affects the secretion of MIR200B mRNA
CTD
PMID:33419253
NCBI chr 1:1,167,104...1,167,198
Ensembl chr 1:1,167,104...1,167,198
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MIR200C
microRNA 200c
multiple interactions
EXP
Zearalenone results in increased expression of and results in decreased secretion of MIR200C mRNA
CTD
PMID:33419253
NCBI chr12:6,963,699...6,963,766
Ensembl chr12:6,963,699...6,963,766
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MIR210
microRNA 210
decreases expression
ISO
Zearalenone results in decreased expression of MIR210 mRNA
CTD
PMID:30717214
NCBI chr11:568,089...568,198
Ensembl chr11:568,089...568,198
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MIR221
microRNA 221
increases expression multiple interactions
ISO EXP
Zearalenone results in increased expression of MIR221 mRNA [Zearalenone co-treated with deoxynivalenol] results in decreased expression of MIR221 mRNA
CTD
PMID:30717214 PMID:35090964
NCBI chr X:45,746,157...45,746,266
Ensembl chr X:45,746,157...45,746,266
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MIR301A
microRNA 301a
decreases expression
ISO
Zearalenone results in decreased expression of MIR301 mRNA
CTD
PMID:30717214
NCBI chr17:59,151,136...59,151,221
Ensembl chr17:59,151,136...59,151,221
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MIR3065
microRNA 3065
increases expression
EXP
Zearalenone results in increased expression of MIR3065 mRNA
CTD
PMID:36828454
NCBI chr17:81,125,877...81,125,955
Ensembl chr17:81,125,877...81,125,955
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MIR326
microRNA 326
decreases expression
ISO
Zearalenone results in decreased expression of MIR326 mRNA
CTD
PMID:30717214
NCBI chr11:75,335,092...75,335,186
Ensembl chr11:75,335,092...75,335,186
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MIR3620
microRNA 3620
increases expression
EXP
Zearalenone results in increased expression of MIR3620 mRNA
CTD
PMID:36828454
NCBI chr 1:228,097,263...228,097,341
Ensembl chr 1:228,097,263...228,097,341
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MIR3661
microRNA 3661
decreases expression
EXP
Zearalenone results in decreased expression of MIR3661 mRNA
CTD
PMID:36828454
NCBI chr 5:134,225,757...134,225,852
Ensembl chr 5:134,225,757...134,225,852
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MIR410
microRNA 410
decreases expression
ISO
Zearalenone results in decreased expression of MIR410 mRNA
CTD
PMID:30717214
NCBI chr14:101,065,912...101,065,991
Ensembl chr14:101,065,912...101,065,991
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MIR411
microRNA 411
decreases expression
ISO
Zearalenone results in decreased expression of MIR411 mRNA
CTD
PMID:30717214
NCBI chr14:101,023,325...101,023,420
Ensembl chr14:101,023,325...101,023,420
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MIR429
microRNA 429
decreases secretion
EXP
Zearalenone results in decreased secretion of MIR429 mRNA
CTD
PMID:33419253
NCBI chr 1:1,169,005...1,169,087
Ensembl chr 1:1,169,005...1,169,087
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MIR451A
microRNA 451a
increases expression
EXP
Zearalenone results in increased expression of MIR451A mRNA
CTD
PMID:36828454
NCBI chr17:28,861,369...28,861,440
Ensembl chr17:28,861,369...28,861,440
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MIR4747
microRNA 4747
increases expression
EXP
Zearalenone results in increased expression of MIR4747 mRNA
CTD
PMID:36828454
NCBI chr19:4,932,687...4,932,740
Ensembl chr19:4,932,687...4,932,740
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MIR5008
microRNA 5008
decreases expression
EXP
Zearalenone results in decreased expression of MIR5008 mRNA
CTD
PMID:36828454
NCBI chr 1:227,941,590...227,941,683
Ensembl chr 1:227,941,590...227,941,683
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MIR501
microRNA 501
decreases expression
EXP
Zearalenone results in decreased expression of MIR501 mRNA
CTD
PMID:36828454
NCBI chr X:50,009,722...50,009,805
Ensembl chr X:50,009,722...50,009,805
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MIR548U
microRNA 548u
increases expression
EXP
Zearalenone results in increased expression of MIR548U mRNA
CTD
PMID:36828454
NCBI chr 6:57,390,132...57,390,212
Ensembl chr 6:57,390,132...57,390,212
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MIR615
microRNA 615
decreases expression
ISO
Zearalenone results in decreased expression of MIR615 mRNA
CTD
PMID:30717214
NCBI chr12:54,033,950...54,034,045
Ensembl chr12:54,033,950...54,034,045
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MIR6795
microRNA 6795
decreases expression
EXP
Zearalenone results in decreased expression of MIR6795 mRNA
CTD
PMID:36828454
NCBI chr19:15,179,283...15,179,350
Ensembl chr19:15,179,283...15,179,350
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MIR6806
microRNA 6806
increases expression
EXP
Zearalenone results in increased expression of MIR6806 mRNA
CTD
PMID:36828454
NCBI chr19:58,334,688...58,334,751
Ensembl chr19:58,334,688...58,334,751
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MIR96
microRNA 96
affects expression
ISO
Zearalenone affects the expression of MIR96 mRNA
CTD
PMID:30717214
NCBI chr 7:129,774,692...129,774,769
Ensembl chr 7:129,774,692...129,774,769
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MKI67
marker of proliferation Ki-67
increases expression
EXP
Zearalenone results in increased expression of MKI67 mRNA
CTD
PMID:28965971
NCBI chr10:128,096,659...128,126,423
Ensembl chr10:128,096,659...128,126,423
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MLH1
mutL homolog 1
increases expression
ISO
Zearalenone results in increased expression of MLH1 mRNA; Zearalenone results in increased expression of MLH1 protein
CTD
PMID:28552778
NCBI chr 3:36,993,466...37,050,846
Ensembl chr 3:36,993,226...37,050,896
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MLPH
melanophilin
increases expression
EXP
Zearalenone results in increased expression of MLPH mRNA
CTD
PMID:19371625
NCBI chr 2:237,486,410...237,555,322
Ensembl chr 2:237,485,428...237,555,322
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MMP2
matrix metallopeptidase 2
increases expression
EXP
Zearalenone results in increased expression of MMP2 mRNA
CTD
PMID:28965971
NCBI chr16:55,478,830...55,506,691
Ensembl chr16:55,389,700...55,506,691
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MMP7
matrix metallopeptidase 7
increases expression
ISO
Zearalenone results in increased expression of MMP7 mRNA
CTD
PMID:17557909
NCBI chr11:102,520,508...102,530,747
Ensembl chr11:102,520,508...102,530,750
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MPO
myeloperoxidase
multiple interactions increases secretion increases activity
ISO
6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [corynoline inhibits the reaction [Zearalenone results in increased activity of MPO protein]]; [Dextran Sulfate co-treated with Zearalenone] results in increased secretion of MPO protein; corynoline inhibits the reaction [Zearalenone results in increased activity of MPO protein]; Zearalenone inhibits the reaction [Dextran Sulfate results in increased secretion of MPO protein] Zearalenone results in increased secretion of MPO protein Gallic Acid inhibits the reaction [Zearalenone results in increased activity of MPO protein]
CTD
PMID:30270565 PMID:34723416 PMID:36161741
NCBI chr17:58,269,855...58,280,935
Ensembl chr17:58,269,855...58,280,935
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MSMB
microseminoprotein beta
increases expression
EXP
Zearalenone results in increased expression of MSMB mRNA
CTD
PMID:19371625
NCBI chr10:46,033,313...46,046,269
Ensembl chr10:46,033,307...46,048,180
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MT-ATP6
mitochondrially encoded ATP synthase membrane subunit 6
decreases expression multiple interactions
EXP
Zearalenone results in decreased expression of ATP6 mRNA [Plant Extracts co-treated with ochratoxin A co-treated with Zearalenone co-treated with beauvericin] results in decreased expression of ATP6 mRNA
CTD
PMID:34015425
NCBI chr MT:8,527...9,207
Ensembl chr MT:8,527...9,207
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MT-ATP8
mitochondrially encoded ATP synthase membrane subunit 8
multiple interactions
EXP
[Plant Extracts co-treated with ochratoxin A co-treated with Zearalenone co-treated with beauvericin] results in decreased expression of ATP8 mRNA; [Plant Extracts co-treated with Zearalenone] results in decreased expression of ATP8 mRNA; [Zearalenone co-treated with ochratoxin A] results in decreased expression of ATP8 mRNA
CTD
PMID:34015425
NCBI chr MT:8,366...8,572
Ensembl chr MT:8,366...8,572
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MT-CO1
mitochondrially encoded cytochrome c oxidase I
multiple interactions decreases expression
EXP
[Plant Extracts co-treated with ochratoxin A co-treated with Zearalenone co-treated with beauvericin] results in decreased expression of COX1 mRNA; [Plant Extracts co-treated with ochratoxin A co-treated with Zearalenone] results in decreased expression of COX1 mRNA; [Plant Extracts co-treated with Zearalenone] results in decreased expression of COX1 mRNA; [Zearalenone co-treated with ochratoxin A] results in decreased expression of COX1 mRNA Zearalenone results in decreased expression of COX1 mRNA
CTD
PMID:34015425
NCBI chr MT:5,904...7,445
Ensembl chr MT:5,904...7,445
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MT-CO3
mitochondrially encoded cytochrome c oxidase III
decreases expression multiple interactions
EXP
Zearalenone results in decreased expression of COX3 mRNA [Plant Extracts co-treated with ochratoxin A co-treated with Zearalenone co-treated with beauvericin] results in decreased expression of COX3 mRNA; [Plant Extracts co-treated with ochratoxin A co-treated with Zearalenone] results in decreased expression of COX3 mRNA; [Plant Extracts co-treated with Zearalenone] results in decreased expression of COX3 mRNA; [Zearalenone co-treated with ochratoxin A] results in decreased expression of COX3 mRNA
CTD
PMID:34015425
NCBI chr MT:9,207...9,990
Ensembl chr MT:9,207...9,990
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MT-ND2
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 2
multiple interactions
EXP
[Plant Extracts co-treated with ochratoxin A co-treated with Zearalenone co-treated with beauvericin] results in increased expression of ND2 mRNA; [Plant Extracts co-treated with ochratoxin A co-treated with Zearalenone] results in increased expression of ND2 mRNA; [Plant Extracts co-treated with Zearalenone] results in increased expression of ND2 mRNA; [Zearalenone co-treated with ochratoxin A] results in increased expression of ND2 mRNA
CTD
PMID:34015425
NCBI chr MT:4,470...5,511
Ensembl chr MT:4,470...5,511
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MT-ND3
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 3
multiple interactions
EXP
[Plant Extracts co-treated with ochratoxin A co-treated with Zearalenone co-treated with beauvericin] results in increased expression of ND3 mRNA; [Plant Extracts co-treated with ochratoxin A co-treated with Zearalenone] results in increased expression of ND3 mRNA; [Plant Extracts co-treated with Zearalenone] results in increased expression of ND3 mRNA; [Zearalenone co-treated with ochratoxin A] results in increased expression of ND3 mRNA
CTD
PMID:34015425
NCBI chr MT:10,059...10,404
Ensembl chr MT:10,059...10,404
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MT-ND4
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4
multiple interactions decreases expression
EXP
[Plant Extracts co-treated with ochratoxin A co-treated with Zearalenone co-treated with beauvericin] results in decreased expression of ND4 mRNA; [Plant Extracts co-treated with Zearalenone] results in increased expression of ND4 mRNA Zearalenone results in decreased expression of ND4 mRNA
CTD
PMID:34015425
NCBI chr MT:10,760...12,137
Ensembl chr MT:10,760...12,137
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MT-ND4L
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4L
multiple interactions
EXP
[Plant Extracts co-treated with Zearalenone] results in increased expression of ND4L mRNA; [Zearalenone co-treated with ochratoxin A] results in increased expression of ND4L mRNA
CTD
PMID:34015425
NCBI chr MT:10,470...10,766
Ensembl chr MT:10,470...10,766
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MT-ND5
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 5
multiple interactions
EXP
[Plant Extracts co-treated with ochratoxin A co-treated with Zearalenone] results in increased expression of ND5 mRNA; [Plant Extracts co-treated with Zearalenone] results in increased expression of ND5 mRNA; [Zearalenone co-treated with ochratoxin A] results in increased expression of ND5 mRNA
CTD
PMID:34015425
NCBI chr MT:12,337...14,148
Ensembl chr MT:12,337...14,148
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MT-ND6
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 6
multiple interactions decreases expression
EXP
[Plant Extracts co-treated with ochratoxin A co-treated with Zearalenone] results in increased expression of ND6 mRNA; [Plant Extracts co-treated with Zearalenone] results in increased expression of ND6 mRNA; [Zearalenone co-treated with ochratoxin A] results in increased expression of ND6 mRNA Zearalenone results in decreased expression of ND6 mRNA
CTD
PMID:34015425
NCBI chr MT:14,149...14,673
Ensembl chr MT:14,149...14,673
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MT-RNR2
mitochondrially encoded 16S rRNA
multiple interactions decreases expression
EXP
[Plant Extracts co-treated with ochratoxin A co-treated with Zearalenone co-treated with beauvericin] results in decreased expression of RNR2 mRNA; [Plant Extracts co-treated with ochratoxin A co-treated with Zearalenone] results in decreased expression of RNR2 mRNA; [Plant Extracts co-treated with Zearalenone] results in decreased expression of RNR2 mRNA; [Zearalenone co-treated with ochratoxin A] results in decreased expression of RNR2 mRNA Zearalenone results in decreased expression of RNR2 mRNA
CTD
PMID:34015425
NCBI chr MT:1,671...3,229
Ensembl chr MT:1,671...3,229
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MTARC2
mitochondrial amidoxime reducing component 2
increases expression
ISO
Zearalenone results in increased expression of MTARC2 protein
CTD
PMID:25058043
NCBI chr 1:220,748,322...220,784,815
Ensembl chr 1:220,748,225...220,784,815
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MTHFD1L
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like
increases expression
ISO
Zearalenone results in increased expression of MTHFD1L protein
CTD
PMID:25058043
NCBI chr 6:150,865,702...151,101,887
Ensembl chr 6:150,865,679...151,101,887
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MTHFD2P7
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase pseudogene 7
increases expression
EXP
Zearalenone results in increased expression of MTHFD2P7 mRNA
CTD
PMID:36828454
NCBI chr 3:179,464,320...179,465,326
Ensembl chr 3:179,464,346...179,465,328
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MTOR
mechanistic target of rapamycin kinase
decreases phosphorylation multiple interactions
ISO
Zearalenone results in decreased phosphorylation of MTOR protein 2-aminoethyl diphenylborinate inhibits the reaction [Zearalenone results in decreased phosphorylation of MTOR protein]; acadesine promotes the reaction [Zearalenone results in decreased phosphorylation of MTOR protein]; Acetylcysteine inhibits the reaction [Zearalenone results in decreased phosphorylation of MTOR protein]; dorsomorphin inhibits the reaction [Zearalenone results in decreased phosphorylation of MTOR protein]
CTD
PMID:31586597 PMID:31982503 PMID:32858132
NCBI chr 1:11,106,535...11,262,551
Ensembl chr 1:11,106,535...11,262,556
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MUC2
mucin 2, oligomeric mucus/gel-forming
multiple interactions
EXP
[Aflatoxin M1 co-treated with Zearalenone co-treated with ochratoxin A] results in decreased expression of MUC2 mRNA; [Aflatoxin M1 co-treated with Zearalenone co-treated with ochratoxin A] results in decreased secretion of MUC2 protein; [Aflatoxin M1 co-treated with Zearalenone] results in decreased expression of MUC2 mRNA; [Aflatoxin M1 co-treated with Zearalenone] results in decreased secretion of MUC2 protein
CTD
PMID:30904571
NCBI chr11:1,074,874...1,110,508
Ensembl chr11:1,074,875...1,110,511
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MUC4
mucin 4, cell surface associated
increases expression
ISO
Zearalenone results in increased expression of MUC4 mRNA
CTD
PMID:17557909
NCBI chr 3:195,746,771...195,811,929
Ensembl chr 3:195,746,765...195,811,973
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MUC5AC
mucin 5AC, oligomeric mucus/gel-forming
increases expression multiple interactions
EXP
Zearalenone results in increased expression of MUC5AC mRNA [Aflatoxin M1 co-treated with Zearalenone co-treated with ochratoxin A] results in decreased expression of MUC5AC mRNA; [Aflatoxin M1 co-treated with Zearalenone co-treated with ochratoxin A] results in increased secretion of MUC5AC protein; [Aflatoxin M1 co-treated with Zearalenone] results in decreased expression of MUC5AC mRNA; Zearalenone results in increased expression of and results in increased secretion of MUC5AC protein
CTD
PMID:24496642 PMID:30904571
NCBI chr11:1,157,953...1,201,138
Ensembl chr11:1,157,953...1,201,138
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MUC5B
mucin 5B, oligomeric mucus/gel-forming
multiple interactions increases expression
EXP
[Aflatoxin M1 co-treated with Zearalenone co-treated with ochratoxin A] results in decreased expression of MUC5B mRNA; [Aflatoxin M1 co-treated with Zearalenone co-treated with ochratoxin A] results in decreased secretion of MUC5B protein; [Aflatoxin M1 co-treated with Zearalenone] results in decreased expression of MUC5B mRNA; [Aflatoxin M1 co-treated with Zearalenone] results in decreased secretion of MUC5B protein; Zearalenone results in increased expression of and results in increased secretion of MUC5B protein Zearalenone results in increased expression of MUC5B mRNA
CTD
PMID:24496642 PMID:30904571
NCBI chr11:1,223,066...1,262,172
Ensembl chr11:1,223,066...1,262,172
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MYC
MYC proto-oncogene, bHLH transcription factor
increases expression
EXP ISO
Zearalenone results in increased expression of MYC mRNA Zearalenone results in increased expression of MYC protein
CTD
PMID:27473017 PMID:28965971 PMID:36828454
NCBI chr 8:127,735,434...127,742,951
Ensembl chr 8:127,735,434...127,742,951
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MYD88
MYD88 innate immune signal transduction adaptor
increases expression
EXP
Zearalenone results in increased expression of MYD88 mRNA
CTD
PMID:27757495
NCBI chr 3:38,138,661...38,143,022
Ensembl chr 3:38,138,552...38,143,024
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N4BP3
NEDD4 binding protein 3
decreases expression
EXP
Zearalenone results in decreased expression of N4BP3 mRNA
CTD
PMID:36828454
NCBI chr 5:178,113,532...178,127,034
Ensembl chr 5:178,113,532...178,126,081
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NAA10
N-alpha-acetyltransferase 10, NatA catalytic subunit
decreases expression
ISO
Zearalenone results in decreased expression of NAA10 protein
CTD
PMID:36252740
NCBI chr X:153,929,225...153,935,037
Ensembl chr X:153,929,225...153,935,080
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NARS1
asparaginyl-tRNA synthetase 1
decreases expression
ISO
Zearalenone results in decreased expression of NARS1 protein
CTD
PMID:36252740
NCBI chr18:57,600,656...57,621,836
Ensembl chr18:57,600,656...57,622,213
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NASP
nuclear autoantigenic sperm protein
decreases expression
ISO
Zearalenone results in decreased expression of NASP mRNA
CTD
PMID:17557909
NCBI chr 1:45,584,041...45,618,893
Ensembl chr 1:45,583,846...45,618,904
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NCMAP
non-compact myelin associated protein
increases expression
EXP
Zearalenone results in increased expression of NCMAP mRNA
CTD
PMID:19371625
NCBI chr 1:24,556,087...24,609,328
Ensembl chr 1:24,556,087...24,609,328
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NCOA2
nuclear receptor coactivator 2
multiple interactions
EXP
Zearalenone analog promotes the reaction [ESR1 protein binds to and results in increased activity of NCOA2 protein]; Zearalenone analog promotes the reaction [ESR2 protein binds to and results in increased activity of NCOA2 protein]; Zearalenone promotes the reaction [ESR1 protein binds to and results in increased activity of NCOA2 protein]; Zearalenone promotes the reaction [ESR2 protein binds to and results in increased activity of NCOA2 protein]; Zearalenone promotes the reaction [NCOA2 protein binds to ESR1 protein]
CTD
PMID:15084758 PMID:28807876
NCBI chr 8:70,109,782...70,456,446
Ensembl chr 8:70,109,782...70,403,808
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NCR3LG1
natural killer cell cytotoxicity receptor 3 ligand 1
increases expression
EXP
Zearalenone results in increased expression of NCR3LG1 mRNA
CTD
PMID:36828454
NCBI chr11:17,351,800...17,381,661
Ensembl chr11:17,351,800...17,377,341
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NDRG1
N-myc downstream regulated 1
decreases expression
EXP
Zearalenone results in decreased expression of NDRG1 mRNA
CTD
PMID:36828454
NCBI chr 8:133,237,175...133,297,252
Ensembl chr 8:133,237,175...133,302,022
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NECTIN4
nectin cell adhesion molecule 4
decreases expression
EXP
Zearalenone results in decreased expression of NECTIN4 mRNA
CTD
PMID:36828454
NCBI chr 1:161,070,998...161,089,558
Ensembl chr 1:161,070,998...161,089,558
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NEIL2
nei like DNA glycosylase 2
increases expression
EXP
Zearalenone results in increased expression of NEIL2 mRNA
CTD
PMID:19371625
NCBI chr 8:11,769,710...11,787,345
Ensembl chr 8:11,769,639...11,787,345
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NFE2L2
NFE2 like bZIP transcription factor 2
increases expression multiple interactions
ISO
Zearalenone results in increased expression of NFE2L2 protein 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [corynoline promotes the reaction [Zearalenone results in increased expression of NFE2L2 protein]]; corynoline promotes the reaction [Zearalenone results in increased expression of NFE2L2 protein]
CTD
PMID:36161741
NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756
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NFKBIA
NFKB inhibitor alpha
increases phosphorylation multiple interactions increases expression
ISO
Zearalenone results in increased phosphorylation of NFKBIA protein 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [corynoline inhibits the reaction [Zearalenone results in increased phosphorylation of NFKBIA protein]]; corynoline inhibits the reaction [Zearalenone results in increased phosphorylation of NFKBIA protein]; Rutin inhibits the reaction [Zearalenone results in increased expression of NFKBIA mRNA]
CTD
PMID:31586597 PMID:36161741 PMID:39053873
NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,079...35,404,749
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NGEF
neuronal guanine nucleotide exchange factor
decreases expression
EXP
Zearalenone results in decreased expression of NGEF mRNA
CTD
PMID:19371625
NCBI chr 2:232,878,701...233,013,256
Ensembl chr 2:232,878,701...233,013,256
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NIBAN2
niban apoptosis regulator 2
decreases expression
EXP
Zearalenone results in decreased expression of NIBAN2 mRNA
CTD
PMID:19371625
NCBI chr 9:127,505,343...127,579,031
Ensembl chr 9:127,505,339...127,578,989
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NLRP3
NLR family pyrin domain containing 3
increases expression multiple interactions
ISO
Zearalenone results in increased expression of NLRP3 mRNA; Zearalenone results in increased expression of NLRP3 protein [Dextran Sulfate co-treated with Zearalenone] results in increased expression of NLRP3 mRNA; [Dextran Sulfate co-treated with Zearalenone] results in increased expression of NLRP3 protein; Dextran Sulfate inhibits the reaction [Zearalenone results in increased expression of NLRP3 mRNA]; Zearalenone inhibits the reaction [Dextran Sulfate results in increased expression of NLRP3 mRNA]; Zearalenone inhibits the reaction [Dextran Sulfate results in increased expression of NLRP3 protein] NLRP3 protein promotes the reaction [[Zearalenone co-treated with Lipopolysaccharides] results in increased expression of CASP1 protein modified form]; NLRP3 protein promotes the reaction [[Zearalenone co-treated with Lipopolysaccharides] results in increased expression of IL1B protein modified form]; NLRP3 protein promotes the reaction [[Zearalenone co-treated with Lipopolysaccharides] results in increased expression of TNF protein]
CTD
PMID:30270565 PMID:31586597
NCBI chr 1:247,416,077...247,448,817
Ensembl chr 1:247,332,331...247,449,108
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NME1
NME/NM23 nucleoside diphosphate kinase 1
increases expression
EXP
Zearalenone results in increased expression of NME1 mRNA
CTD
PMID:28965971
NCBI chr17:51,153,559...51,162,168
Ensembl chr17:51,153,559...51,162,428
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NMNAT1
nicotinamide nucleotide adenylyltransferase 1
decreases expression
ISO
Zearalenone results in decreased expression of NMNAT1 mRNA
CTD
PMID:38159578
NCBI chr 1:9,942,923...9,996,892
Ensembl chr 1:9,943,428...9,985,501
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NMNAT2
nicotinamide nucleotide adenylyltransferase 2
decreases expression
ISO
Zearalenone results in decreased expression of NMNAT2 mRNA
CTD
PMID:38159578
NCBI chr 1:183,248,237...183,418,380
Ensembl chr 1:183,248,237...183,418,380
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NMRAL1
NmrA like redox sensor 1
decreases expression
ISO
Zearalenone results in decreased expression of NMRAL1 protein
CTD
PMID:36252740
NCBI chr16:4,461,694...4,476,337
Ensembl chr16:4,461,691...4,495,763
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NOBOX
NOBOX oogenesis homeobox
decreases expression
ISO
Zearalenone results in decreased expression of NOBOX mRNA
CTD
PMID:28089945
NCBI chr 7:144,396,900...144,410,227
Ensembl chr 7:144,397,240...144,410,227
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NOTCH1
notch receptor 1
multiple interactions
EXP
[Zearalenone co-treated with Aflatoxin B1] results in increased expression of NOTCH1 mRNA
CTD
PMID:28965971
NCBI chr 9:136,494,433...136,546,048
Ensembl chr 9:136,494,433...136,546,048
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NPY1R
neuropeptide Y receptor Y1
increases expression
EXP
Zearalenone results in increased expression of NPY1R mRNA
CTD
PMID:36828454
NCBI chr 4:163,323,962...163,344,689
Ensembl chr 4:163,323,962...163,344,832
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NR1H3
nuclear receptor subfamily 1 group H member 3
increases expression
EXP ISO
Zearalenone results in increased expression of NR1H3 mRNA
CTD
PMID:32119988 PMID:38159578
NCBI chr11:47,248,300...47,269,033
Ensembl chr11:47,248,300...47,269,033
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NR1I2
nuclear receptor subfamily 1 group I member 2
increases activity decreases expression multiple interactions affects binding
EXP ISO
Zearalenone results in increased activity of NR1I2 protein Zearalenone results in decreased expression of NR1I2 mRNA Zearalenone binds to and results in increased activity of NR1I2 protein; Zearalenone promotes the reaction [NR1I2 protein results in increased expression of CYP3A4] Zearalenone binds to NR1I2 protein
CTD
PMID:15569515 PMID:20607812 PMID:33049310 PMID:36893891
NCBI chr 3:119,782,101...119,818,487
Ensembl chr 3:119,780,484...119,818,487
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NR1I3
nuclear receptor subfamily 1 group I member 3
increases activity
EXP
Zearalenone results in increased activity of NR1I3 protein
CTD
PMID:28927721
NCBI chr 1:161,229,669...161,238,203
Ensembl chr 1:161,229,666...161,238,244
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NR3C1
nuclear receptor subfamily 3 group C member 1
decreases expression
EXP
Zearalenone results in decreased expression of NR3C1 mRNA
CTD
PMID:28965971
NCBI chr 5:143,277,931...143,435,512
Ensembl chr 5:143,277,931...143,435,512
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NR4A1
nuclear receptor subfamily 4 group A member 1
decreases expression multiple interactions increases expression
ISO
Zearalenone results in decreased expression of NR4A1 protein Colforsin promotes the reaction [Zearalenone results in increased expression of NR4A1 mRNA]
CTD
PMID:24512812 PMID:26783879
NCBI chr12:52,022,832...52,059,503
Ensembl chr12:52,022,832...52,059,507
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NR5A1
nuclear receptor subfamily 5 group A member 1
decreases expression
ISO
Zearalenone results in decreased expression of NR5A1 mRNA; Zearalenone results in decreased expression of NR5A1 protein
CTD
PMID:29669061
NCBI chr 9:124,481,236...124,507,399
Ensembl chr 9:124,481,236...124,507,420
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NRIP1
nuclear receptor interacting protein 1
increases expression
EXP
Zearalenone results in increased expression of NRIP1 mRNA
CTD
PMID:19371625
NCBI chr21:14,961,235...15,065,936
Ensembl chr21:14,961,235...15,065,936
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NRTN
neurturin
increases expression
EXP
Zearalenone results in increased expression of NRTN mRNA
CTD
PMID:19371625
NCBI chr19:5,805,067...5,828,324
Ensembl chr19:5,805,067...5,828,324
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NT5C
5', 3'-nucleotidase, cytosolic
decreases expression
ISO
Zearalenone results in decreased expression of NT5C protein
CTD
PMID:36252740
NCBI chr17:75,130,228...75,131,742
Ensembl chr17:75,130,225...75,131,757
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NUBP2
NUBP iron-sulfur cluster assembly factor 2, cytosolic
decreases expression
ISO
Zearalenone results in decreased expression of NUBP2 protein
CTD
PMID:36252740
NCBI chr16:1,782,960...1,789,186
Ensembl chr16:1,782,932...1,789,186
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NUCB2
nucleobindin 2
increases expression
ISO
Zearalenone results in increased expression of NUCB2 protein
CTD
PMID:36252740
NCBI chr11:17,276,739...17,349,980
Ensembl chr11:17,208,153...17,349,980
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NUDCD2
NudC domain containing 2
decreases expression
ISO
Zearalenone results in decreased expression of NUDCD2 protein
CTD
PMID:36252740
NCBI chr 5:163,446,526...163,460,102
Ensembl chr 5:163,446,526...163,460,404
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NUDT5
nudix hydrolase 5
decreases expression
ISO
Zearalenone results in decreased expression of NUDT5 protein
CTD
PMID:36252740
NCBI chr10:12,165,330...12,195,891
Ensembl chr10:12,165,330...12,195,891
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NXNL2
nucleoredoxin like 2
increases expression
EXP
Zearalenone results in increased expression of NXNL2 mRNA
CTD
PMID:36828454
NCBI chr 9:88,535,178...88,584,510
Ensembl chr 9:88,534,033...88,584,274
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ODAPH
odontogenesis associated phosphoprotein
decreases expression
EXP
Zearalenone results in decreased expression of ODAPH mRNA
CTD
PMID:36828454
NCBI chr 4:75,556,066...75,565,893
Ensembl chr 4:75,556,048...75,565,871
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OLFM1
olfactomedin 1
increases expression
EXP
Zearalenone results in increased expression of OLFM1 mRNA
CTD
PMID:19371625 PMID:36828454
NCBI chr 9:135,075,505...135,121,184
Ensembl chr 9:135,075,422...135,121,180
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OLFML3
olfactomedin like 3
increases expression
EXP
Zearalenone results in increased expression of OLFML3 mRNA
CTD
PMID:19371625 PMID:36828454
NCBI chr 1:113,979,474...113,982,253
Ensembl chr 1:113,979,391...114,035,572
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OSGIN1
oxidative stress induced growth inhibitor 1
multiple interactions increases expression
EXP
[Zearalenone co-treated with ochratoxin A] results in increased expression of OSGIN1 mRNA Zearalenone results in increased expression of OSGIN1 mRNA
CTD
PMID:34015425
NCBI chr16:83,953,240...83,966,332
Ensembl chr16:83,931,311...83,966,332
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OXSR1
oxidative stress responsive kinase 1
decreases expression
ISO
Zearalenone results in decreased expression of OXSR1 protein
CTD
PMID:36252740
NCBI chr 3:38,164,063...38,255,484
Ensembl chr 3:38,165,089...38,255,484
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P4HB
prolyl 4-hydroxylase subunit beta
multiple interactions
ISO
[Zearalenone co-treated with CGA protein] results in decreased expression of P4HB protein
CTD
PMID:25058043
NCBI chr17:81,843,166...81,860,535
Ensembl chr17:81,843,159...81,860,856
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PAFAH1B2
platelet activating factor acetylhydrolase 1b catalytic subunit 2
decreases expression
ISO
Zearalenone results in decreased expression of PAFAH1B2 protein
CTD
PMID:36252740
NCBI chr11:117,144,287...117,178,173
Ensembl chr11:117,144,284...117,176,894
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PAFAH1B3
platelet activating factor acetylhydrolase 1b catalytic subunit 3
decreases expression
ISO
Zearalenone results in decreased expression of PAFAH1B3 protein
CTD
PMID:36252740
NCBI chr19:42,297,033...42,302,800
Ensembl chr19:42,297,033...42,303,546
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PAICS
phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase
decreases expression
ISO
Zearalenone results in decreased expression of PAICS protein
CTD
PMID:25058043
NCBI chr 4:56,410,507...56,464,578
Ensembl chr 4:56,435,741...56,464,578
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PAK2
p21 (RAC1) activated kinase 2
decreases expression
ISO
Zearalenone results in decreased expression of PAK2 protein
CTD
PMID:36252740
NCBI chr 3:196,739,857...196,832,647
Ensembl chr 3:196,739,857...196,832,647
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PALM3
paralemmin 3
decreases expression
EXP
Zearalenone results in decreased expression of PALM3 mRNA
CTD
PMID:36828454
NCBI chr19:14,053,367...14,062,076
Ensembl chr19:14,053,363...14,062,076
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PARP1
poly(ADP-ribose) polymerase 1
increases cleavage decreases expression multiple interactions increases expression
ISO
Zearalenone results in increased cleavage of PARP1 protein Zearalenone results in decreased expression of PARP1 protein Nicotinamide Mononucleotide inhibits the reaction [Zearalenone results in increased expression of PARP1 mRNA]
CTD
PMID:24530352 PMID:28089945 PMID:38159578
NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,210...226,408,154
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PBDC1
polysaccharide biosynthesis domain containing 1
decreases expression
ISO
Zearalenone results in decreased expression of PBDC1 protein
CTD
PMID:36252740
NCBI chr X:76,173,062...76,178,314
Ensembl chr X:76,173,040...76,178,755
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PC
pyruvate carboxylase
increases expression decreases expression
ISO
Zearalenone results in increased expression of PCX protein Zearalenone results in decreased expression of PC mRNA; Zearalenone results in decreased expression of PC protein
CTD
PMID:25058043 PMID:32858132
NCBI chr11:66,848,420...66,958,383
Ensembl chr11:66,848,417...66,958,386
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PCK2
phosphoenolpyruvate carboxykinase 2, mitochondrial
increases expression
ISO
Zearalenone results in increased expression of PCK2 protein
CTD
PMID:25058043
NCBI chr14:24,094,171...24,104,125
Ensembl chr14:24,094,053...24,110,598
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PCLAF
PCNA clamp associated factor
decreases expression
EXP
Zearalenone results in decreased expression of PCLAF mRNA
CTD
PMID:19371625
NCBI chr15:64,364,304...64,387,687
Ensembl chr15:64,364,304...64,387,687
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PDCD1
programmed cell death 1
increases expression
EXP
Zearalenone results in increased expression of PDCD1 mRNA
CTD
PMID:27757495
NCBI chr 2:241,849,884...241,858,894
Ensembl chr 2:241,849,884...241,858,894
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PDCD6IP
programmed cell death 6 interacting protein
multiple interactions
ISO
[Zearalenone co-treated with CGA protein] results in increased expression of PDCD6IP protein
CTD
PMID:25058043
NCBI chr 3:33,798,630...33,869,703
Ensembl chr 3:33,798,571...33,869,707
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PDCD7
programmed cell death 7
increases expression
EXP
Zearalenone results in increased expression of PDCD7 mRNA
CTD
PMID:19371625
NCBI chr15:65,117,379...65,133,808
Ensembl chr15:65,117,379...65,133,808
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PDE3B
phosphodiesterase 3B
increases expression
EXP
Zearalenone results in increased expression of PDE3B mRNA
CTD
PMID:36828454
NCBI chr11:14,643,804...14,899,321
Ensembl chr11:14,643,804...14,872,044
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PDGFRL
platelet derived growth factor receptor like
increases expression
EXP
Zearalenone results in increased expression of PDGFRL mRNA
CTD
PMID:36828454
NCBI chr 8:17,576,433...17,643,144
Ensembl chr 8:17,576,433...17,644,071
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PDHA1
pyruvate dehydrogenase E1 subunit alpha 1
increases expression
ISO
Zearalenone results in increased expression of PDHA1 protein
CTD
PMID:25058043
NCBI chr X:19,343,927...19,361,718
Ensembl chr X:19,343,893...19,361,718
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PDXDC1
pyridoxal dependent decarboxylase domain containing 1
decreases expression
ISO
Zearalenone results in decreased expression of PDXDC1 protein
CTD
PMID:36252740
NCBI chr16:14,974,735...15,153,218
Ensembl chr16:14,974,591...15,153,671
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PFKFB2
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
decreases expression
EXP
Zearalenone results in decreased expression of PFKFB2 mRNA
CTD
PMID:19371625
NCBI chr 1:207,034,416...207,081,027
Ensembl chr 1:207,034,366...207,081,024
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PFKL
phosphofructokinase, liver type
decreases expression
ISO
Zearalenone results in decreased expression of PFKL protein
CTD
PMID:36252740
NCBI chr21:44,300,053...44,327,373
Ensembl chr21:44,300,051...44,327,376
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PGD
phosphogluconate dehydrogenase
decreases expression
ISO
Zearalenone results in decreased expression of PGD protein
CTD
PMID:25058043
NCBI chr 1:10,399,064...10,420,511
Ensembl chr 1:10,398,592...10,420,511
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PGK1
phosphoglycerate kinase 1
decreases expression multiple interactions
ISO
Zearalenone results in decreased expression of PGK1 protein Nicotinamide Mononucleotide inhibits the reaction [Zearalenone results in decreased expression of PGK1 protein]
CTD
PMID:25058043 PMID:36252740 PMID:38159578
NCBI chr X:78,104,248...78,129,295
Ensembl chr X:77,910,739...78,129,295
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PGPEP1
pyroglutamyl-peptidase I
decreases expression
ISO
Zearalenone results in decreased expression of PGPEP1 protein
CTD
PMID:36252740
NCBI chr19:18,340,598...18,369,950
Ensembl chr19:18,340,598...18,369,950
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PGR
progesterone receptor
increases expression multiple interactions
EXP
Zearalenone results in increased expression of PGR mRNA; Zearalenone results in increased expression of PGR protein deoxynivalenol promotes the reaction [Zearalenone results in increased expression of PGR mRNA]; Fulvestrant inhibits the reaction [Zearalenone results in increased expression of PGR protein]; PPARG inhibits the reaction [Zearalenone results in increased expression of PGR mRNA]; Zearalenone inhibits the reaction [Progesterone binds to and results in increased activity of PGR protein]
CTD
PMID:19371625 PMID:21803136 PMID:28807876 PMID:28965971 PMID:35588983
NCBI chr11:101,029,624...101,129,813
Ensembl chr11:101,029,624...101,129,813
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PHB1
prohibitin 1
increases expression
ISO
Zearalenone results in increased expression of PHB1 protein
CTD
PMID:25058043
NCBI chr17:49,404,052...49,414,882
Ensembl chr17:49,404,049...49,414,905
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PHB2
prohibitin 2
increases expression
ISO
Zearalenone results in increased expression of PHB2 protein
CTD
PMID:25058043
NCBI chr12:6,965,327...6,970,753
Ensembl chr12:6,965,327...6,970,780
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PHF11
PHD finger protein 11
decreases expression
EXP
Zearalenone results in decreased expression of PHF11 mRNA
CTD
PMID:19371625
NCBI chr13:49,495,953...49,528,976
Ensembl chr13:49,495,610...49,528,981
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PHGDH
phosphoglycerate dehydrogenase
multiple interactions decreases expression
ISO
[Zearalenone co-treated with CGA protein] results in increased expression of PHGDH protein Zearalenone results in decreased expression of PHGDH protein
CTD
PMID:25058043 PMID:36252740
NCBI chr 1:119,711,934...119,744,215
Ensembl chr 1:119,648,411...119,744,218
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PIK3CD
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
increases expression
ISO
Zearalenone results in increased expression of PIK3CD mRNA
CTD
PMID:30138655
NCBI chr 1:9,627,258...9,729,114
Ensembl chr 1:9,629,889...9,729,114
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PIM1
Pim-1 proto-oncogene, serine/threonine kinase
increases expression
EXP
Zearalenone results in increased expression of PIM1 mRNA
CTD
PMID:19371625
NCBI chr 6:37,170,152...37,175,428
Ensembl chr 6:37,170,152...37,175,428
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PIPOX
pipecolic acid and sarcosine oxidase
increases expression
EXP
Zearalenone results in increased expression of PIPOX mRNA
CTD
PMID:36828454
NCBI chr17:29,043,141...29,057,216
Ensembl chr17:28,950,513...29,057,216
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PIWIL1
piwi like RNA-mediated gene silencing 1
decreases expression
ISO
Zearalenone results in decreased expression of PIWIL1 protein
CTD
PMID:31419471
NCBI chr12:130,337,887...130,426,260
Ensembl chr12:130,337,887...130,372,637
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PKDCC
protein kinase domain containing, cytoplasmic
increases expression
EXP
Zearalenone results in increased expression of PKDCC mRNA
CTD
PMID:36828454
NCBI chr 2:42,048,021...42,058,517
Ensembl chr 2:42,048,021...42,058,517
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PLAT
plasminogen activator, tissue type
increases expression
EXP
Zearalenone results in increased expression of PLAT mRNA
CTD
PMID:36828454
NCBI chr 8:42,174,718...42,207,565
Ensembl chr 8:42,174,718...42,207,709
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PLCB1
phospholipase C beta 1
increases expression
EXP
Zearalenone results in increased expression of PLCB1 mRNA
CTD
PMID:19371625 PMID:36828454
NCBI chr20:8,132,266...8,884,900
Ensembl chr20:8,077,251...8,968,360
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PLCH1
phospholipase C eta 1
increases expression
ISO
Zearalenone results in increased expression of PLCH1 protein
CTD
PMID:36252740
NCBI chr 3:155,450,934...155,745,071
Ensembl chr 3:155,375,580...155,745,071
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PLG
plasminogen
increases expression
EXP
Zearalenone results in increased expression of PLG mRNA
CTD
PMID:36828454
NCBI chr 6:160,702,193...160,754,097
Ensembl chr 6:160,702,194...160,754,097
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PLIN1
perilipin 1
increases expression
ISO
Zearalenone results in increased expression of PLIN1 protein
CTD
PMID:25058043
NCBI chr15:89,664,367...89,679,367
Ensembl chr15:89,664,367...89,679,427
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PLPPR2
phospholipid phosphatase related 2
increases expression
EXP
Zearalenone results in increased expression of PLPPR2 mRNA
CTD
PMID:19371625
NCBI chr19:11,355,432...11,365,698
Ensembl chr19:11,355,386...11,365,698
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PLXDC2
plexin domain containing 2
increases expression
EXP
Zearalenone results in increased expression of PLXDC2 mRNA
CTD
PMID:19371625
NCBI chr10:19,816,432...20,289,856
Ensembl chr10:19,816,239...20,289,856
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PMM2
phosphomannomutase 2
decreases expression
ISO
Zearalenone results in decreased expression of PMM2 protein
CTD
PMID:36252740
NCBI chr16:8,797,839...8,849,325
Ensembl chr16:8,788,823...8,862,534
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PNPLA2
patatin like phospholipase domain containing 2
increases expression multiple interactions
ISO
Zearalenone results in increased expression of PNPLA2 protein Nicotinamide Mononucleotide inhibits the reaction [Zearalenone results in increased expression of PNPLA2 protein]
CTD
PMID:38159578
NCBI chr11:818,914...825,573
Ensembl chr11:818,914...825,573
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PNPT1P1
polyribonucleotide nucleotidyltransferase 1 pseudogene 1
increases expression
EXP
Zearalenone results in increased expression of PNPT1P1 mRNA
CTD
PMID:36828454
NCBI chr 3:3,982,523...3,984,297
Ensembl chr 3:3,981,981...3,984,295
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POLR2C
RNA polymerase II subunit C
increases expression
EXP
Zearalenone results in increased expression of POLR2C mRNA
CTD
PMID:19371625
NCBI chr16:57,462,679...57,472,009
Ensembl chr16:57,462,660...57,472,009
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POU2F3
POU class 2 homeobox 3
decreases expression
EXP
Zearalenone results in decreased expression of POU2F3 mRNA
CTD
PMID:36828454
NCBI chr11:120,236,638...120,319,945
Ensembl chr11:120,236,640...120,319,945
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PPA1
inorganic pyrophosphatase 1
decreases expression
ISO
Zearalenone results in decreased expression of PPA1 protein
CTD
PMID:36252740
NCBI chr10:70,202,835...70,233,429
Ensembl chr10:70,202,835...70,233,911
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PPARA
peroxisome proliferator activated receptor alpha
increases expression
EXP
Zearalenone results in increased expression of PPARA mRNA
CTD
PMID:32119988
NCBI chr22:46,150,526...46,243,756
Ensembl chr22:46,150,521...46,243,755
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PPARD
peroxisome proliferator activated receptor delta
multiple interactions increases expression
ISO
Nicotinamide Mononucleotide inhibits the reaction [Zearalenone results in increased expression of PPARD mRNA]
CTD
PMID:38159578
NCBI chr 6:35,342,558...35,428,178
Ensembl chr 6:35,342,558...35,428,191
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PPARG
peroxisome proliferator activated receptor gamma
decreases activity decreases methylation increases expression multiple interactions
EXP ISO
Zearalenone results in decreased activity of PPARG protein Zearalenone results in decreased methylation of PPARG promoter Zearalenone results in increased expression of PPARG mRNA; Zearalenone results in increased expression of PPARG protein PPARG inhibits the reaction [Zearalenone results in increased expression of PGR mRNA]; PPARG inhibits the reaction [Zearalenone results in increased expression of TFF1 mRNA] Nicotinamide Mononucleotide inhibits the reaction [Zearalenone results in increased expression of PPARG mRNA]
CTD
PMID:27481073 PMID:32119988 PMID:35588983 PMID:38159578
NCBI chr 3:12,287,368...12,434,344
Ensembl chr 3:12,287,368...12,434,356
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PPARGC1B
PPARG coactivator 1 beta
increases expression
EXP
Zearalenone results in increased expression of PPARGC1B mRNA
CTD
PMID:36828454
NCBI chr 5:149,730,310...149,857,959
Ensembl chr 5:149,730,298...149,855,022
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PPP1R1A
protein phosphatase 1 regulatory inhibitor subunit 1A
increases expression
EXP
Zearalenone results in increased expression of PPP1R1A mRNA
CTD
PMID:36828454
NCBI chr12:54,579,246...54,588,659
Ensembl chr12:54,575,387...54,588,659
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PRDM14
PR/SET domain 14
increases expression
EXP
Zearalenone results in increased expression of PRDM14 mRNA
CTD
PMID:19371625
NCBI chr 8:70,051,651...70,071,252
Ensembl chr 8:70,051,651...70,071,693
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PREP
prolyl endopeptidase
decreases expression
ISO
Zearalenone results in decreased expression of PREP protein
CTD
PMID:25058043
NCBI chr 6:105,273,218...105,403,082
Ensembl chr 6:105,273,218...105,454,062
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PRH1
proline rich protein HaeIII subfamily 1
decreases expression
ISO
Zearalenone results in decreased expression of PRH1 mRNA
CTD
PMID:17557909
NCBI chr12:10,880,965...11,171,611
Ensembl chr12:10,824,960...11,171,608
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PRKAA2
protein kinase AMP-activated catalytic subunit alpha 2
increases expression
ISO
Zearalenone results in increased expression of PRKAA2 mRNA
CTD
PMID:30717214
NCBI chr 1:56,645,314...56,715,335
Ensembl chr 1:56,645,314...56,715,335
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PRKAR2A
protein kinase cAMP-dependent type II regulatory subunit alpha
increases expression
EXP
Zearalenone results in increased expression of PRKAR2A mRNA
CTD
PMID:19371625
NCBI chr 3:48,744,591...48,847,874
Ensembl chr 3:48,744,597...48,847,874
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PRMT6
protein arginine methyltransferase 6
increases expression
EXP
Zearalenone results in increased expression of PRMT6 mRNA
CTD
PMID:32119988
NCBI chr 1:107,056,674...107,059,294
Ensembl chr 1:107,056,674...107,067,636
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PRPS2
phosphoribosyl pyrophosphate synthetase 2
decreases expression
ISO
Zearalenone results in decreased expression of PRPS2 protein
CTD
PMID:36252740
NCBI chr X:12,791,412...12,824,222
Ensembl chr X:12,791,355...12,824,222
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PRSS23
serine protease 23
increases expression
EXP
Zearalenone results in increased expression of PRSS23 mRNA
CTD
PMID:22494775
NCBI chr11:86,791,071...86,952,910
Ensembl chr11:86,791,059...86,952,910
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PRUNE1
prune exopolyphosphatase 1
decreases expression
ISO
Zearalenone results in decreased expression of PRUNE1 protein
CTD
PMID:36252740
NCBI chr 1:151,008,449...151,035,713
Ensembl chr 1:151,008,420...151,035,713
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PSMC1
proteasome 26S subunit, ATPase 1
decreases expression
ISO
Zearalenone results in decreased expression of PSMC1 protein
CTD
PMID:36252740
NCBI chr14:90,256,553...90,275,429
Ensembl chr14:90,256,527...90,275,429
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PSMC2
proteasome 26S subunit, ATPase 2
decreases expression
ISO
Zearalenone results in decreased expression of PSMC2 protein
CTD
PMID:36252740
NCBI chr 7:103,347,524...103,369,395
Ensembl chr 7:103,328,570...103,370,346
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PSMC3
proteasome 26S subunit, ATPase 3
decreases expression
ISO
Zearalenone results in decreased expression of PSMC3 protein
CTD
PMID:36252740
NCBI chr11:47,418,775...47,426,439
Ensembl chr11:47,418,769...47,426,473
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PSMC4
proteasome 26S subunit, ATPase 4
decreases expression
ISO
Zearalenone results in decreased expression of PSMC4 protein
CTD
PMID:36252740
NCBI chr19:39,971,165...39,981,764
Ensembl chr19:39,971,165...39,981,764
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PSMD13
proteasome 26S subunit, non-ATPase 13
decreases expression
ISO
Zearalenone results in decreased expression of PSMD13 protein
CTD
PMID:36252740
NCBI chr11:236,976...252,984
Ensembl chr11:236,966...252,984
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PSMD2
proteasome 26S subunit ubiquitin receptor, non-ATPase 2
decreases expression
ISO
Zearalenone results in decreased expression of PSMD2 protein
CTD
PMID:36252740
NCBI chr 3:184,299,241...184,309,050
Ensembl chr 3:184,299,198...184,309,050
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PSMG2
proteasome assembly chaperone 2
decreases expression
ISO
Zearalenone results in decreased expression of PSMG2 protein
CTD
PMID:36252740
NCBI chr18:12,658,738...12,725,740
Ensembl chr18:12,658,043...12,728,945
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PTEN
phosphatase and tensin homolog
increases expression decreases expression
ISO
Zearalenone results in increased expression of PTEN mRNA Zearalenone results in decreased expression of PTEN protein
CTD
PMID:27473017 PMID:30717214
NCBI chr10:87,863,625...87,971,930
Ensembl chr10:87,862,638...87,971,930
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PTGES3
prostaglandin E synthase 3
decreases expression
ISO
Zearalenone results in decreased expression of PTGES3 protein
CTD
PMID:36252740
NCBI chr12:56,663,349...56,688,284
Ensembl chr12:56,663,341...56,688,408
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PTGR2
prostaglandin reductase 2
decreases expression
ISO
Zearalenone results in decreased expression of PTGR2 protein
CTD
PMID:36252740
NCBI chr14:73,851,831...73,885,726
Ensembl chr14:73,851,831...73,885,726
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PTGS2
prostaglandin-endoperoxide synthase 2
increases expression
EXP
Zearalenone results in increased expression of PTGS2 mRNA
CTD
PMID:27757495 PMID:36828454
NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922
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PTK2
protein tyrosine kinase 2
decreases expression
ISO
Zearalenone results in decreased expression of PTK2 protein
CTD
PMID:36288102
NCBI chr 8:140,657,900...141,002,079
Ensembl chr 8:140,657,900...141,002,216
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PUS7
pseudouridine synthase 7
increases expression
EXP
Zearalenone results in increased expression of PUS7 mRNA
CTD
PMID:36828454
NCBI chr 7:105,456,501...105,522,271
Ensembl chr 7:105,439,661...105,522,271
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PYCARD
PYD and CARD domain containing
multiple interactions increases expression
ISO
[Dextran Sulfate co-treated with Zearalenone] results in increased expression of PYCARD mRNA; [Dextran Sulfate co-treated with Zearalenone] results in increased expression of PYCARD protein; Zearalenone inhibits the reaction [Dextran Sulfate results in increased expression of PYCARD mRNA]; Zearalenone inhibits the reaction [Dextran Sulfate results in increased expression of PYCARD protein] Zearalenone results in increased expression of PYCARD mRNA; Zearalenone results in increased expression of PYCARD protein [Zearalenone co-treated with Lipopolysaccharides] results in increased expression of PYCARD protein
CTD
PMID:30270565 PMID:31586597
NCBI chr16:31,201,486...31,202,760
Ensembl chr16:31,201,486...31,203,450
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RAB20
RAB20, member RAS oncogene family
decreases expression
EXP
Zearalenone results in decreased expression of RAB20 mRNA
CTD
PMID:19371625
NCBI chr13:110,523,066...110,561,722
Ensembl chr13:110,523,066...110,561,722
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RACK1
receptor for activated C kinase 1
increases expression
EXP
Zearalenone results in increased expression of RACK1 mRNA; Zearalenone results in increased expression of RACK1 protein
CTD
PMID:32328699
NCBI chr 5:181,236,897...181,243,906
Ensembl chr 5:181,236,897...181,248,096
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RAD51
RAD51 recombinase
decreases expression increases expression
ISO
Zearalenone results in decreased expression of RAD51 mRNA Zearalenone results in increased expression of RAD51 mRNA; Zearalenone results in increased expression of RAD51 protein
CTD
PMID:27862621 PMID:28552778 PMID:35650142
NCBI chr15:40,694,733...40,732,340
Ensembl chr15:40,694,774...40,732,340
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RAF1
Raf-1 proto-oncogene, serine/threonine kinase
increases expression
ISO
Zearalenone results in increased expression of RAF1 mRNA
CTD
PMID:29758222
NCBI chr 3:12,583,601...12,664,117
Ensembl chr 3:12,582,101...12,664,201
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RANBP1
RAN binding protein 1
decreases expression
ISO
Zearalenone results in decreased expression of RANBP1 protein
CTD
PMID:36252740
NCBI chr22:20,116,104...20,127,355
Ensembl chr22:20,115,938...20,127,355
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RAP1A
RAP1A, member of RAS oncogene family
decreases expression
ISO
Zearalenone results in decreased expression of RAP1A mRNA
CTD
PMID:30717214
NCBI chr 1:111,542,009...111,716,691
Ensembl chr 1:111,542,218...111,716,691
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RAP1B
RAP1B, member of RAS oncogene family
decreases expression
ISO
Zearalenone results in decreased expression of RAP1B mRNA
CTD
PMID:30717214
NCBI chr12:68,610,899...68,671,901
Ensembl chr12:68,610,855...68,671,901
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RAPGEF4
Rap guanine nucleotide exchange factor 4
increases expression
EXP
Zearalenone results in increased expression of RAPGEF4 mRNA
CTD
PMID:36828454
NCBI chr 2:172,735,318...173,052,893
Ensembl chr 2:172,735,274...173,052,893
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RARB
retinoic acid receptor beta
decreases expression
EXP
Zearalenone results in decreased expression of RARB mRNA
CTD
PMID:28965971
NCBI chr 3:24,829,321...25,597,932
Ensembl chr 3:24,687,887...25,597,932
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RARS1
arginyl-tRNA synthetase 1
decreases expression
ISO
Zearalenone results in decreased expression of RARS1 protein
CTD
PMID:25058043
NCBI chr 5:168,486,471...168,519,301
Ensembl chr 5:168,486,451...168,519,301
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RASGRP1
RAS guanyl releasing protein 1
increases expression
EXP
Zearalenone results in increased expression of RASGRP1 mRNA
CTD
PMID:36828454
NCBI chr15:38,488,103...38,564,814
Ensembl chr15:38,488,103...38,565,575
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RASSF1
Ras association domain family member 1
increases expression
EXP
Zearalenone results in increased expression of RASSF1 mRNA
CTD
PMID:28965971
NCBI chr 3:50,329,788...50,340,836
Ensembl chr 3:50,329,782...50,340,980
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RASSF2
Ras association domain family member 2
decreases expression
EXP
Zearalenone results in decreased expression of RASSF2 mRNA
CTD
PMID:36828454
NCBI chr20:4,780,023...4,823,608
Ensembl chr20:4,780,023...4,823,608
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RBBP8
RB binding protein 8, endonuclease
increases expression
EXP
Zearalenone results in increased expression of RBBP8 mRNA
CTD
PMID:36828454
NCBI chr18:22,914,139...23,026,486
Ensembl chr18:22,798,261...23,026,488
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RBBP8NL
RBBP8 N-terminal like
decreases expression
EXP
Zearalenone results in decreased expression of RBBP8NL mRNA
CTD
PMID:36828454
NCBI chr20:62,410,237...62,427,539
Ensembl chr20:62,410,237...62,427,539
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RBM24
RNA binding motif protein 24
increases expression
EXP
Zearalenone results in increased expression of RBM24 mRNA
CTD
PMID:19371625
NCBI chr 6:17,281,361...17,293,871
Ensembl chr 6:17,281,361...17,293,871
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RBP1
retinol binding protein 1
decreases expression
EXP
Zearalenone results in decreased expression of RBP1 mRNA
CTD
PMID:19371625
NCBI chr 3:139,517,438...139,539,742
Ensembl chr 3:139,517,434...139,539,829
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REL
REL proto-oncogene, NF-kB subunit
decreases expression
ISO
Zearalenone results in decreased expression of REL protein
CTD
PMID:36252740
NCBI chr 2:60,881,574...60,931,612
Ensembl chr 2:60,881,491...60,931,612
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RELA
RELA proto-oncogene, NF-kB subunit
multiple interactions increases phosphorylation increases expression
ISO
3-methyladenine promotes the reaction [Zearalenone results in increased phosphorylation of and affects the localization of RELA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Zearalenone results in increased phosphorylation of and affects the localization of RELA protein]; Sirolimus inhibits the reaction [Zearalenone results in increased phosphorylation of and affects the localization of RELA protein]; Zearalenone results in increased phosphorylation of and affects the localization of RELA protein Zearalenone results in increased phosphorylation of RELA protein 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [corynoline inhibits the reaction [Zearalenone results in increased phosphorylation of RELA protein]]; corynoline inhibits the reaction [Zearalenone results in increased phosphorylation of RELA protein]; Rutin inhibits the reaction [Zearalenone results in increased expression of RELA mRNA]
CTD
PMID:31586597 PMID:36161741 PMID:39053873
NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090
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RFK
riboflavin kinase
decreases expression
ISO
Zearalenone results in decreased expression of RFK protein
CTD
PMID:36252740
NCBI chr 9:76,385,526...76,394,426
Ensembl chr 9:76,385,526...76,394,517
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RHOBTB1
Rho related BTB domain containing 1
increases expression
EXP
Zearalenone results in increased expression of RHOBTB1 mRNA
CTD
PMID:36828454
NCBI chr10:60,860,860...61,001,967
Ensembl chr10:60,869,438...61,001,440
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RIBC2
RIB43A domain with coiled-coils 2
decreases expression
EXP
Zearalenone results in decreased expression of RIBC2 mRNA
CTD
PMID:19371625
NCBI chr22:45,413,693...45,432,509
Ensembl chr22:45,413,693...45,432,509
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RIMS4
regulating synaptic membrane exocytosis 4
increases expression
EXP
Zearalenone results in increased expression of RIMS4 mRNA
CTD
PMID:36828454
NCBI chr20:44,751,808...44,810,546
Ensembl chr20:44,751,808...44,810,546
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RIPK1
receptor interacting serine/threonine kinase 1
increases expression multiple interactions
ISO
Zearalenone results in increased expression of RIPK1 mRNA; Zearalenone results in increased expression of RIPK1 protein RIPK1 protein affects the reaction [Zearalenone results in increased cleavage of CASP3 protein]; scutellarin affects the reaction [RIPK1 protein affects the reaction [Zearalenone results in increased cleavage of CASP3 protein]]; scutellarin inhibits the reaction [Zearalenone results in increased expression of RIPK1 mRNA]; scutellarin inhibits the reaction [Zearalenone results in increased expression of RIPK1 protein]
CTD
PMID:36252740
NCBI chr 6:3,063,967...3,115,187
Ensembl chr 6:3,063,824...3,115,187
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RMI2
RecQ mediated genome instability 2
decreases expression
EXP
Zearalenone results in decreased expression of RMI2 mRNA
CTD
PMID:19371625
NCBI chr16:11,345,459...11,351,760
Ensembl chr16:11,249,619...11,381,662
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RNF224
ring finger protein 224
decreases expression
EXP
Zearalenone results in decreased expression of RNF224 mRNA
CTD
PMID:36828454
NCBI chr 9:137,227,502...137,229,640
Ensembl chr 9:137,227,502...137,229,640
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RNH1
ribonuclease/angiogenin inhibitor 1
decreases expression
ISO
Zearalenone results in decreased expression of RNH1 protein
CTD
PMID:25058043 PMID:36252740
NCBI chr11:494,515...507,242
Ensembl chr11:494,512...507,300
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RPA3
replication protein A3
decreases expression
ISO
Zearalenone results in decreased expression of RPA3 protein
CTD
PMID:36252740
NCBI chr 7:7,636,518...7,718,607
Ensembl chr 7:7,636,518...7,718,607
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RPL14
ribosomal protein L14
decreases expression
ISO
Zearalenone results in decreased expression of RPL14 mRNA
CTD
PMID:30138655
NCBI chr 3:40,457,339...40,468,587
Ensembl chr 3:40,457,292...40,468,587
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RPL23A
ribosomal protein L23a
decreases expression
ISO
Zearalenone results in decreased expression of RPL23A mRNA
CTD
PMID:30138655
NCBI chr17:28,719,985...28,724,359
Ensembl chr17:28,719,985...28,724,359
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RPS23
ribosomal protein S23
decreases expression
ISO
Zearalenone results in decreased expression of RPS23 protein
CTD
PMID:36252740
NCBI chr 5:82,273,320...82,278,354
Ensembl chr 5:82,273,320...82,278,396
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RPS3
ribosomal protein S3
decreases expression
ISO
Zearalenone results in decreased expression of RPS3 protein
CTD
PMID:35504548
NCBI chr11:75,399,518...75,422,302
Ensembl chr11:75,399,515...75,422,280
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RPS5
ribosomal protein S5
decreases expression
ISO
Zearalenone results in decreased expression of RPS5 mRNA
CTD
PMID:30138655
NCBI chr19:58,387,269...58,394,804
Ensembl chr19:58,386,400...58,394,806
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RPS6
ribosomal protein S6
decreases expression
ISO
Zearalenone results in decreased expression of RPS6 protein
CTD
PMID:36252740
NCBI chr 9:19,375,715...19,380,236
Ensembl chr 9:19,375,715...19,380,236
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RPS6KB1
ribosomal protein S6 kinase B1
multiple interactions decreases phosphorylation
ISO
2-aminoethyl diphenylborinate inhibits the reaction [Zearalenone results in decreased phosphorylation of RPS6KB1 protein]; acadesine promotes the reaction [Zearalenone results in decreased phosphorylation of RPS6KB1 protein]; Acetylcysteine inhibits the reaction [Zearalenone results in decreased phosphorylation of RPS6KB1 protein]; dorsomorphin inhibits the reaction [Zearalenone results in decreased phosphorylation of RPS6KB1 protein]; HERPUD1 protein inhibits the reaction [Zearalenone results in decreased phosphorylation of RPS6KB1 protein]
CTD
PMID:30394307 PMID:31982503
NCBI chr17:59,893,121...59,950,574
Ensembl chr17:59,893,046...59,950,574
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RPS8
ribosomal protein S8
decreases expression
ISO
Zearalenone results in decreased expression of RPS8 mRNA
CTD
PMID:30138655
NCBI chr 1:44,775,540...44,778,779
Ensembl chr 1:44,775,251...44,778,779
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RRAGB
Ras related GTP binding B
decreases expression
EXP
Zearalenone results in decreased expression of RRAGB mRNA
CTD
PMID:19371625
NCBI chr X:55,717,749...55,758,774
Ensembl chr X:55,717,749...55,758,774
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RRS1
ribosome biogenesis regulator 1 homolog
increases expression
EXP
Zearalenone results in increased expression of RRS1 mRNA
CTD
PMID:36828454
NCBI chr 8:66,429,014...66,430,733
Ensembl chr 8:66,429,014...66,430,733
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RTL10
retrotransposon Gag like 10
increases expression
EXP
Zearalenone results in increased expression of RTL10 mRNA
CTD
PMID:19371625
NCBI chr22:19,846,146...19,854,874
Ensembl chr22:19,846,138...19,854,896
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RUBCNL
rubicon like autophagy enhancer
increases expression
EXP
Zearalenone results in increased expression of RUBCNL mRNA
CTD
PMID:36828454
NCBI chr13:46,334,681...46,390,042
Ensembl chr13:46,334,681...46,438,190
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S100A6
S100 calcium binding protein A6
decreases expression
ISO
Zearalenone results in decreased expression of S100A6 protein
CTD
PMID:36252740
NCBI chr 1:153,534,599...153,535,991
Ensembl chr 1:153,534,599...153,536,244
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S100G
S100 calcium binding protein G
increases expression
ISO
Zearalenone results in increased expression of S100G mRNA
CTD
PMID:17557909
NCBI chr X:16,650,158...16,654,670
Ensembl chr X:16,650,158...16,654,670
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S1PR3
sphingosine-1-phosphate receptor 3
increases expression
EXP
Zearalenone results in increased expression of S1PR3 mRNA
CTD
PMID:19371625
NCBI chr 9:88,990,863...89,005,155
Ensembl chr 9:88,990,863...89,005,155
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SAE1
SUMO1 activating enzyme subunit 1
decreases expression
ISO
Zearalenone results in decreased expression of SAE1 protein
CTD
PMID:36252740
NCBI chr19:47,130,835...47,210,636
Ensembl chr19:47,113,274...47,210,636
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SAMM50
SAMM50 sorting and assembly machinery component
increases expression
ISO
Zearalenone results in increased expression of SAMM50 protein
CTD
PMID:25058043
NCBI chr22:43,955,442...43,996,529
Ensembl chr22:43,955,442...44,010,531
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SAR1A
secretion associated Ras related GTPase 1A
decreases expression
ISO
Zearalenone results in decreased expression of SAR1A protein
CTD
PMID:36252740
NCBI chr10:70,147,289...70,170,514
Ensembl chr10:70,147,289...70,170,523
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SAT1
spermidine/spermine N1-acetyltransferase 1
decreases expression
EXP
Zearalenone results in decreased expression of SAT1 mRNA
CTD
PMID:19371625
NCBI chr X:23,783,173...23,786,210
Ensembl chr X:23,783,173...23,786,210
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SCAND2P
SCAN domain containing 2 pseudogene
increases expression
EXP
Zearalenone results in increased expression of SCAND2P mRNA
CTD
PMID:19371625
NCBI chr15:84,631,460...84,642,463
Ensembl chr15:84,631,963...84,642,066
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SEC31A
SEC31 homolog A, COPII coat complex component
decreases expression
ISO
Zearalenone results in decreased expression of SEC31A protein
CTD
PMID:36252740
NCBI chr 4:82,818,509...82,900,569
Ensembl chr 4:82,818,509...82,901,166
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SERBP1
SERPINE1 mRNA binding protein 1
decreases expression
ISO
Zearalenone results in decreased expression of SERBP1 protein
CTD
PMID:25058043
NCBI chr 1:67,407,810...67,430,402
Ensembl chr 1:67,407,810...67,430,415
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SERPINE1
serpin family E member 1
multiple interactions
EXP
[Zearalenone co-treated with Aflatoxin B1] results in increased expression of SERPINE1 mRNA
CTD
PMID:28965971
NCBI chr 7:101,127,104...101,139,247
Ensembl chr 7:101,127,104...101,139,247
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SEZ6
seizure related 6 homolog
increases expression
EXP
Zearalenone results in increased expression of SEZ6 mRNA
CTD
PMID:36828454
NCBI chr17:28,954,905...29,006,440
Ensembl chr17:28,954,901...29,006,440
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SF3B5
splicing factor 3b subunit 5
increases expression
EXP
Zearalenone results in increased expression of SF3B5 mRNA
CTD
PMID:19371625
NCBI chr 6:144,094,884...144,095,573
Ensembl chr 6:144,094,884...144,095,573
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SFTPD
surfactant protein D
increases expression
ISO
Zearalenone results in increased expression of SFTPD mRNA
CTD
PMID:17557909
NCBI chr10:79,937,740...79,982,383
Ensembl chr10:79,937,467...79,982,614
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SIAH1
siah E3 ubiquitin protein ligase 1
decreases expression
EXP
Zearalenone results in decreased expression of SIAH1 mRNA
CTD
PMID:19371625
NCBI chr16:48,360,531...48,387,246
Ensembl chr16:48,356,364...48,448,402
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SIRT1
sirtuin 1
decreases expression multiple interactions increases expression
ISO
Zearalenone results in decreased expression of SIRT1 protein 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [corynoline inhibits the reaction [Zearalenone results in decreased expression of SIRT1 protein]]; corynoline inhibits the reaction [Zearalenone results in decreased expression of SIRT1 protein]; Nicotinamide Mononucleotide inhibits the reaction [Zearalenone results in increased expression of SIRT1 mRNA]
CTD
PMID:36161741 PMID:38159578
NCBI chr10:67,884,656...67,918,390
Ensembl chr10:67,884,656...67,918,390
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SLC12A8
solute carrier family 12 member 8
multiple interactions decreases expression
ISO
Nicotinamide Mononucleotide inhibits the reaction [Zearalenone results in decreased expression of SLC12A8 mRNA]
CTD
PMID:38159578
NCBI chr 3:125,082,644...125,212,748
Ensembl chr 3:125,082,636...125,212,864
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SLC19A2
solute carrier family 19 member 2
increases expression
EXP
Zearalenone results in increased expression of SLC19A2 mRNA
CTD
PMID:36828454
NCBI chr 1:169,463,909...169,485,970
Ensembl chr 1:169,463,909...169,485,944
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SLC1A5
solute carrier family 1 member 5
increases expression decreases expression
EXP ISO
Zearalenone results in increased expression of SLC1A5 mRNA Zearalenone results in decreased expression of SLC1A5 mRNA; Zearalenone results in decreased expression of SLC1A5 protein
CTD
PMID:19371625 PMID:32858132
NCBI chr19:46,774,883...46,788,594
Ensembl chr19:46,774,883...46,788,594
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SLC22A3
solute carrier family 22 member 3
increases expression
EXP
Zearalenone results in increased expression of SLC22A3 mRNA
CTD
PMID:36828454
NCBI chr 6:160,348,378...160,452,577
Ensembl chr 6:160,348,378...160,452,577
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SLC26A9
solute carrier family 26 member 9
decreases expression
EXP
Zearalenone results in decreased expression of SLC26A9 mRNA
CTD
PMID:36828454
NCBI chr 1:205,913,052...205,943,456
Ensembl chr 1:205,913,048...205,943,460
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SLC2A2
solute carrier family 2 member 2
increases expression
EXP
Zearalenone results in increased expression of SLC2A2 mRNA
CTD
PMID:32119988
NCBI chr 3:170,996,347...171,026,720
Ensembl chr 3:170,996,347...171,026,743
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SLC31A1
solute carrier family 31 member 1
increases expression
EXP
Zearalenone results in increased expression of SLC31A1 mRNA
CTD
PMID:19371625
NCBI chr 9:113,221,544...113,264,492
Ensembl chr 9:113,221,544...113,264,492
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SLC37A2
solute carrier family 37 member 2
increases expression
ISO
Zearalenone results in increased expression of SLC37A2 protein
CTD
PMID:36252740
NCBI chr11:125,063,305...125,090,516
Ensembl chr11:125,063,302...125,090,516
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SLC38A1
solute carrier family 38 member 1
decreases expression
ISO
Zearalenone results in decreased expression of SLC38A1 mRNA; Zearalenone results in decreased expression of SLC38A1 protein
CTD
PMID:32858132
NCBI chr12:46,183,063...46,269,043
Ensembl chr12:46,183,063...46,270,017
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SLC39A6
solute carrier family 39 member 6
increases expression
EXP
Zearalenone results in increased expression of SLC39A6 mRNA
CTD
PMID:28965971
NCBI chr18:36,108,531...36,129,340
Ensembl chr18:36,108,531...36,129,385
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SLC3A2
solute carrier family 3 member 2
increases expression
EXP
Zearalenone results in increased expression of SLC3A2 mRNA
CTD
PMID:19371625
NCBI chr11:62,856,109...62,888,860
Ensembl chr11:62,856,004...62,888,880
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SLC41A3
solute carrier family 41 member 3
decreases expression
EXP
Zearalenone results in decreased expression of SLC41A3 mRNA
CTD
PMID:19371625
NCBI chr 3:126,006,357...126,101,520
Ensembl chr 3:126,006,357...126,101,561
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SLC6A15
solute carrier family 6 member 15
increases expression
EXP
Zearalenone results in increased expression of SLC6A15 mRNA
CTD
PMID:36828454
NCBI chr12:84,859,491...84,912,799
Ensembl chr12:84,859,491...84,913,629
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SLC6A6
solute carrier family 6 member 6
increases expression
EXP
Zearalenone results in increased expression of SLC6A6 mRNA
CTD
PMID:19371625
NCBI chr 3:14,402,576...14,489,349
Ensembl chr 3:14,402,576...14,489,349
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SLC7A11
solute carrier family 7 member 11
increases expression
EXP
Zearalenone results in increased expression of SLC7A11 mRNA
CTD
PMID:25424538
NCBI chr 4:138,164,097...138,312,671
Ensembl chr 4:138,164,097...138,242,349
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SLC7A2
solute carrier family 7 member 2
increases expression
EXP
Zearalenone results in increased expression of SLC7A2 mRNA
CTD
PMID:36828454
NCBI chr 8:17,494,069...17,570,566
Ensembl chr 8:17,497,088...17,570,573
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SLC7A5
solute carrier family 7 member 5
increases expression
EXP
Zearalenone results in increased expression of SLC7A5 mRNA
CTD
PMID:19371625 PMID:36828454
NCBI chr16:87,830,023...87,869,507
Ensembl chr16:87,830,016...87,869,507
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SLCO1A2
solute carrier organic anion transporter family member 1A2
decreases activity
EXP
Zearalenone results in decreased activity of SLCO1A2 protein
CTD
PMID:38341109
NCBI chr12:21,264,600...21,419,634
Ensembl chr12:21,264,600...21,419,594
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SLCO1B1
solute carrier organic anion transporter family member 1B1
decreases activity
EXP
Zearalenone results in decreased activity of SLCO1B1 protein
CTD
PMID:38341109
NCBI chr12:21,131,194...21,239,796
Ensembl chr12:21,131,194...21,239,796
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SLCO1B3
solute carrier organic anion transporter family member 1B3
decreases activity
EXP
Zearalenone results in decreased activity of SLCO1B3 protein
CTD
PMID:38341109
NCBI chr12:20,810,705...20,916,911
Ensembl chr12:20,810,702...20,916,911
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SLCO2B1
solute carrier organic anion transporter family member 2B1
decreases activity
EXP
Zearalenone results in decreased activity of SLCO2B1 protein
CTD
PMID:38341109
NCBI chr11:75,151,107...75,206,549
Ensembl chr11:75,100,563...75,206,549
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SLIT2
slit guidance ligand 2
decreases expression
EXP
Zearalenone results in decreased expression of SLIT2 mRNA
CTD
PMID:28965971
NCBI chr 4:20,251,905...20,620,561
Ensembl chr 4:20,251,905...20,620,561
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SLITRK4
SLIT and NTRK like family member 4
increases expression
EXP
Zearalenone results in increased expression of SLITRK4 mRNA
CTD
PMID:36828454
NCBI chr X:143,622,790...143,636,101
Ensembl chr X:143,622,790...143,636,101
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SMAD3
SMAD family member 3
multiple interactions increases expression
ISO
[Tamoxifen co-treated with Zearalenone] results in increased expression of SMAD3 mRNA Zearalenone results in increased expression of SMAD3 mRNA
CTD
PMID:30138655
NCBI chr15:67,065,602...67,195,169
Ensembl chr15:67,063,763...67,195,173
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SMPDL3B
sphingomyelin phosphodiesterase acid like 3B
multiple interactions
ISO
[Zearalenone co-treated with CGA protein] results in decreased expression of SMPDL3B protein
CTD
PMID:25058043
NCBI chr 1:27,935,000...27,959,152
Ensembl chr 1:27,935,000...27,959,157
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SNAI2
snail family transcriptional repressor 2
decreases expression
EXP
Zearalenone results in decreased expression of SNAI2 mRNA
CTD
PMID:28965971
NCBI chr 8:48,917,598...48,921,429
Ensembl chr 8:48,917,598...48,921,740
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SNHG32
small nucleolar RNA host gene 32
decreases expression
EXP
Zearalenone results in decreased expression of SNHG32 mRNA
CTD
PMID:19371625
NCBI chr 6:31,834,916...31,839,761
Ensembl chr 6:31,822,094...31,839,766
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SOD1
superoxide dismutase 1
decreases expression multiple interactions
ISO
Zearalenone results in decreased expression of SOD1 mRNA; Zearalenone results in decreased expression of SOD1 protein Nicotinamide Mononucleotide inhibits the reaction [Zearalenone results in decreased expression of SOD1 protein]
CTD
PMID:32858132 PMID:38159578
NCBI chr21:31,659,693...31,668,931
Ensembl chr21:31,659,666...31,668,931
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SOD2
superoxide dismutase 2
decreases expression multiple interactions
ISO
Zearalenone results in decreased expression of SOD2 mRNA; Zearalenone results in decreased expression of SOD2 protein [Nicotinamide Mononucleotide co-treated with Zearalenone] results in decreased expression of SOD2 mRNA
CTD
PMID:32858132 PMID:38159578
NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529
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SOHLH2
spermatogenesis and oogenesis specific basic helix-loop-helix 2
decreases expression
ISO
Zearalenone results in decreased expression of SOHLH2 mRNA
CTD
PMID:28089945
NCBI chr13:36,168,217...36,214,556
Ensembl chr13:36,168,217...36,214,588
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SOX9
SRY-box transcription factor 9
decreases expression
ISO
Zearalenone results in decreased expression of SOX9 mRNA
CTD
PMID:24412631
NCBI chr17:72,121,020...72,126,416
Ensembl chr17:72,121,020...72,126,416
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SPATA2
spermatogenesis associated 2
decreases expression
ISO
Zearalenone results in decreased expression of SPATA2 mRNA
CTD
PMID:24412631
NCBI chr20:49,903,391...49,915,529
Ensembl chr20:49,903,391...49,915,529
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SPSB3
splA/ryanodine receptor domain and SOCS box containing 3
decreases expression
EXP
Zearalenone results in decreased expression of SPSB3 mRNA
CTD
PMID:19371625
NCBI chr16:1,776,712...1,782,571
Ensembl chr16:1,776,712...1,793,700
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SQLE
squalene epoxidase
decreases expression
EXP
Zearalenone results in decreased expression of SQLE mRNA
CTD
PMID:19371625 PMID:25424538
NCBI chr 8:124,998,505...125,022,283
Ensembl chr 8:124,998,497...125,022,283
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SQSTM1
sequestosome 1
increases expression decreases expression
ISO
Zearalenone results in increased expression of SQSTM1 protein Zearalenone results in decreased expression of SQSTM1 mRNA; Zearalenone results in decreased expression of SQSTM1 protein
CTD
PMID:31586597 PMID:31982503 PMID:32858132 PMID:34537261
NCBI chr 5:179,806,393...179,838,078
Ensembl chr 5:179,806,398...179,838,078
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SRD5A1
steroid 5 alpha-reductase 1
decreases activity decreases expression
ISO
Zearalenone results in decreased activity of SRD5A1 protein Zearalenone results in decreased expression of SRD5A1 mRNA
CTD
PMID:29669061
NCBI chr 5:6,633,440...6,674,386
Ensembl chr 5:6,633,290...6,676,539
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SREBF1
sterol regulatory element binding transcription factor 1
increases expression
ISO
Zearalenone results in increased expression of SREBF1 mRNA
CTD
PMID:38159578
NCBI chr17:17,811,334...17,836,986
Ensembl chr17:17,810,399...17,837,002
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SRXN1
sulfiredoxin 1
multiple interactions decreases expression
EXP
[Plant Extracts co-treated with Zearalenone] results in decreased expression of SRXN1 mRNA; [Zearalenone co-treated with ochratoxin A] results in decreased expression of SRXN1 mRNA Zearalenone results in decreased expression of SRXN1 mRNA
CTD
PMID:34015425
NCBI chr20:646,615...653,200
Ensembl chr20:646,615...653,200
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SSC4D
scavenger receptor cysteine rich family member with 4 domains
decreases expression
EXP
Zearalenone results in decreased expression of SSC4D mRNA
CTD
PMID:19371625
NCBI chr 7:76,389,337...76,409,697
Ensembl chr 7:76,389,334...76,409,697
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SSU72
SSU72 homolog, RNA polymerase II CTD phosphatase
decreases expression
ISO
Zearalenone results in decreased expression of SSU72 protein
CTD
PMID:36252740
NCBI chr 1:1,541,673...1,574,863
Ensembl chr 1:1,541,673...1,574,863
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ST8SIA1
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
decreases expression
EXP
Zearalenone results in decreased expression of ST8SIA1 mRNA
CTD
PMID:36828454
NCBI chr12:22,193,391...22,334,707
Ensembl chr12:22,063,773...22,437,041
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STAR
steroidogenic acute regulatory protein
multiple interactions increases expression decreases expression
ISO
Colforsin affects the reaction [Zearalenone results in increased expression of STAR mRNA] Zearalenone results in decreased expression of STAR mRNA; Zearalenone results in decreased expression of STAR protein
CTD
PMID:24512812 PMID:26783879 PMID:29627501
NCBI chr 8:38,142,700...38,150,952
Ensembl chr 8:38,142,700...38,150,992
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STAT5A
signal transducer and activator of transcription 5A
decreases expression
ISO
Zearalenone results in decreased expression of STAT5A mRNA
CTD
PMID:30138655
NCBI chr17:42,287,439...42,311,943
Ensembl chr17:42,287,547...42,311,943
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STK31
serine/threonine kinase 31
decreases expression
ISO
Zearalenone results in decreased expression of STK31 protein
CTD
PMID:31419471
NCBI chr 7:23,710,082...23,832,513
Ensembl chr 7:23,710,203...23,832,513
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STOML2
stomatin like 2
increases expression
ISO
Zearalenone results in increased expression of STOML2 protein
CTD
PMID:25058043
NCBI chr 9:35,099,776...35,103,195
Ensembl chr 9:35,099,776...35,103,195
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STRA8
stimulated by retinoic acid 8
decreases expression
ISO
Zearalenone results in decreased expression of STRA8 mRNA
CTD
PMID:28552778
NCBI chr 7:135,231,915...135,258,663
Ensembl chr 7:135,231,979...135,258,663
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STRAP
serine/threonine kinase receptor associated protein
decreases expression
ISO
Zearalenone results in decreased expression of STRAP protein
CTD
PMID:36252740
NCBI chr12:15,882,387...15,903,478
Ensembl chr12:15,882,387...15,903,478
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SULT1E1
sulfotransferase family 1E member 1
decreases activity
EXP
Zearalenone results in decreased activity of SULT1E1 protein
CTD
PMID:16914110
NCBI chr 4:69,821,122...69,860,145
Ensembl chr 4:69,841,212...69,860,145
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SYAP1
synapse associated protein 1
multiple interactions
ISO
[Zearalenone co-treated with CGA protein] results in decreased expression of SYAP1 protein
CTD
PMID:25058043
NCBI chr X:16,719,612...16,765,340
Ensembl chr X:16,719,612...16,765,340
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SYCP1
synaptonemal complex protein 1
increases expression
ISO
Zearalenone results in increased expression of SYCP1 mRNA
CTD
PMID:24412631
NCBI chr 1:114,854,088...114,995,370
Ensembl chr 1:114,854,863...114,995,370
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SYCP3
synaptonemal complex protein 3
decreases expression
ISO
Zearalenone results in decreased expression of SYCP3 mRNA; Zearalenone results in decreased expression of SYCP3 protein
CTD
PMID:24412631 PMID:28552778 PMID:31419471
NCBI chr12:101,728,648...101,739,462
Ensembl chr12:101,728,648...101,739,472
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SYNCRIP
synaptotagmin binding cytoplasmic RNA interacting protein
decreases expression
ISO
Zearalenone results in decreased expression of SYNCRIP protein
CTD
PMID:36252740
NCBI chr 6:85,607,784...85,643,870
Ensembl chr 6:85,607,779...85,644,063
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TALDO1
transaldolase 1
decreases expression
ISO
Zearalenone results in decreased expression of TALDO1 protein
CTD
PMID:25058043
NCBI chr11:747,464...765,012
Ensembl chr11:747,415...765,012
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TBCEL
tubulin folding cofactor E like
decreases expression
ISO
Zearalenone results in decreased expression of TBCEL protein
CTD
PMID:36252740
NCBI chr11:121,024,102...121,090,776
Ensembl chr11:121,024,072...121,090,776
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TEAD3
TEA domain transcription factor 3
increases expression
ISO
Zearalenone results in increased expression of TEAD3 mRNA
CTD
PMID:30138655
NCBI chr 6:35,473,597...35,497,079
Ensembl chr 6:35,473,597...35,497,079
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TF
transferrin
affects expression decreases expression multiple interactions
EXP
Zearalenone affects the expression of TF mRNA Zearalenone results in decreased expression of TF mRNA [deoxynivalenol co-treated with Zearalenone] affects the expression of TF mRNA; [deoxynivalenol co-treated with Zearalenone] results in increased expression of TF mRNA
CTD
PMID:28865950 PMID:28935499
NCBI chr 3:133,661,998...133,796,641
Ensembl chr 3:133,746,040...133,796,641
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TFAP4
transcription factor AP-4
increases expression
EXP
Zearalenone results in increased expression of TFAP4 mRNA
CTD
PMID:36828454
NCBI chr16:4,257,186...4,273,023
Ensembl chr16:4,257,186...4,273,075
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TFF1
trefoil factor 1
multiple interactions increases expression
EXP
deoxynivalenol promotes the reaction [Zearalenone results in increased expression of TFF1 mRNA]; PPARG inhibits the reaction [Zearalenone results in increased expression of TFF1 mRNA]
CTD
PMID:35588983
NCBI chr21:42,362,282...42,366,535
Ensembl chr21:42,362,282...42,366,535
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TFF3
trefoil factor 3
increases expression
EXP
Zearalenone results in increased expression of TFF3 mRNA
CTD
PMID:28965971
NCBI chr21:42,311,667...42,315,409
Ensembl chr21:42,311,667...42,315,409
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TGFA
transforming growth factor alpha
increases expression
EXP
Zearalenone results in increased expression of TGFA mRNA
CTD
PMID:19371625
NCBI chr 2:70,447,284...70,553,826
Ensembl chr 2:70,447,284...70,554,193
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TGFB2
transforming growth factor beta 2
decreases expression
ISO
Zearalenone results in decreased expression of TGFB2 mRNA
CTD
PMID:27862621 PMID:29758222
NCBI chr 1:218,345,336...218,444,619
Ensembl chr 1:218,345,336...218,444,619
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TGM1
transglutaminase 1
decreases expression
EXP
Zearalenone results in decreased expression of TGM1 mRNA
CTD
PMID:36828454
NCBI chr14:24,249,114...24,263,177
Ensembl chr14:24,249,114...24,264,432
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TH
tyrosine hydroxylase
decreases expression
EXP
Zearalenone results in decreased expression of TH mRNA
CTD
PMID:24412706
NCBI chr11:2,163,929...2,171,815
Ensembl chr11:2,163,929...2,171,815
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THBS1
thrombospondin 1
increases expression decreases expression
EXP
Zearalenone results in increased expression of THBS1 mRNA Zearalenone results in decreased expression of THBS1 mRNA
CTD
PMID:19371625 PMID:28965971
NCBI chr15:39,581,079...39,599,466
Ensembl chr15:39,581,079...39,599,466
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THRA
thyroid hormone receptor alpha
multiple interactions
EXP
Zearalenone binds to and results in increased activity of THRA protein
CTD
PMID:33049310
NCBI chr17:40,062,193...40,093,867
Ensembl chr17:40,058,290...40,093,867
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THRB
thyroid hormone receptor beta
multiple interactions decreases activity
EXP
[15-acetyldeoxynivalenol co-treated with 3-acetyldeoxynivalenol co-treated with deoxynivalenol co-treated with zearalenol co-treated with Zearalenone] results in decreased activity of THRB protein; Zearalenone inhibits the reaction [Triiodothyronine results in increased activity of THRB protein] Zearalenone results in decreased activity of THRB protein
CTD
PMID:27481073 PMID:31077750
NCBI chr 3:24,117,153...24,495,708
Ensembl chr 3:24,117,153...24,495,756
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TIMM17A
translocase of inner mitochondrial membrane 17A
increases expression
ISO
Zearalenone results in increased expression of TIMM17A protein
CTD
PMID:36252740
NCBI chr 1:201,955,503...201,970,664
Ensembl chr 1:201,955,503...201,970,664
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TINF2
TERF1 interacting nuclear factor 2
decreases expression
EXP
Zearalenone results in decreased expression of TINF2 mRNA
CTD
PMID:19371625
NCBI chr14:24,239,640...24,242,674
Ensembl chr14:24,238,286...24,242,663
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TKT
transketolase
decreases expression
ISO
Zearalenone results in decreased expression of TKT protein
CTD
PMID:25058043
NCBI chr 3:53,224,712...53,256,022
Ensembl chr 3:53,224,712...53,256,052
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TLN1
talin 1
multiple interactions
ISO
[Zearalenone co-treated with CGA protein] results in increased expression of TLN1 protein
CTD
PMID:25058043
NCBI chr 9:35,696,948...35,732,195
Ensembl chr 9:35,696,948...35,732,195
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TLR3
toll like receptor 3
increases expression
EXP
Zearalenone results in increased expression of TLR3 mRNA
CTD
PMID:27757495
NCBI chr 4:186,069,156...186,088,073
Ensembl chr 4:186,068,911...186,088,073
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TLR4
toll like receptor 4
increases expression multiple interactions
ISO
Zearalenone results in increased expression of TLR4 mRNA Rutin inhibits the reaction [Zearalenone results in increased expression of TLR4 mRNA]
CTD
PMID:39053873
NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735
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TM6SF1
transmembrane 6 superfamily member 1
increases expression
EXP
Zearalenone results in increased expression of TM6SF1 mRNA
CTD
PMID:25424538
NCBI chr15:83,107,645...83,137,408
Ensembl chr15:83,107,572...83,144,854
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TMEM121
transmembrane protein 121
decreases expression
EXP
Zearalenone results in decreased expression of TMEM121 mRNA
CTD
PMID:19371625
NCBI chr14:105,526,583...105,530,198
Ensembl chr14:105,526,583...105,530,198
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TMEM215
transmembrane protein 215
increases expression
EXP
Zearalenone results in increased expression of TMEM215 mRNA
CTD
PMID:36828454
NCBI chr 9:32,783,540...32,789,201
Ensembl chr 9:32,783,540...32,789,201
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TMEM54
transmembrane protein 54
decreases expression
EXP
Zearalenone results in decreased expression of TMEM54 mRNA
CTD
PMID:19371625
NCBI chr 1:32,894,595...32,901,389
Ensembl chr 1:32,894,594...32,901,438
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TMPRSS2
transmembrane serine protease 2
decreases expression
EXP
Zearalenone results in decreased expression of TMPRSS2 mRNA
CTD
PMID:36828454
NCBI chr21:41,464,305...41,508,158
Ensembl chr21:41,464,300...41,531,116
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TNF
tumor necrosis factor
multiple interactions increases expression
ISO EXP
6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [corynoline inhibits the reaction [Zearalenone results in increased expression of TNF protein]]; [Rutin co-treated with Zearalenone] results in increased expression of TNF mRNA; corynoline inhibits the reaction [Zearalenone results in increased expression of TNF protein]; Lipopolysaccharides promotes the reaction [Zearalenone results in increased expression of TNF mRNA]; Lycopene inhibits the reaction [Zearalenone results in increased expression of TNF]; Nicotinamide Mononucleotide inhibits the reaction [Zearalenone results in increased expression of TNF mRNA]; Rutin inhibits the reaction [Zearalenone results in increased expression of TNF protein] Zearalenone results in increased expression of TNF; Zearalenone results in increased expression of TNF mRNA; Zearalenone results in increased expression of TNF protein 3-methyladenine promotes the reaction [[Zearalenone co-treated with Lipopolysaccharides] results in increased expression of TNF protein]; [Zearalenone co-treated with Lipopolysaccharides] results in increased expression of TNF mRNA; [Zearalenone co-treated with Lipopolysaccharides] results in increased expression of TNF protein; Gallic Acid inhibits the reaction [Zearalenone results in increased expression of TNF protein]; N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide inhibits the reaction [[Zearalenone co-treated with Lipopolysaccharides] results in increased expression of TNF mRNA]; N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide inhibits the reaction [[Zearalenone co-treated with Lipopolysaccharides] results in increased expression of TNF protein]; NLRP3 protein promotes the reaction [[Zearalenone co-treated with Lipopolysaccharides] results in increased expression of TNF protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Zearalenone co-treated with Lipopolysaccharides] results in increased expression of TNF mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Zearalenone results in increased expression of TNF protein]; Sirolimus inhibits the reaction [[Zearalenone co-treated with Lipopolysaccharides] results in increased expression of TNF protein] [Lipopolysaccharides co-treated with Zearalenone] results in increased secretion of TNF protein
CTD
PMID:16687389 PMID:25682699 PMID:31586597 PMID:32328699 PMID:34723416 PMID:36161741 PMID:38159578 PMID:39053873 More...
NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
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TNFRSF25
TNF receptor superfamily member 25
decreases expression
EXP
Zearalenone results in decreased expression of TNFRSF25 mRNA
CTD
PMID:19371625
NCBI chr 1:6,460,786...6,466,173
Ensembl chr 1:6,460,786...6,466,175
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TNFSF10
TNF superfamily member 10
increases expression
EXP
Zearalenone results in increased expression of TNFSF10 mRNA
CTD
PMID:27757495
NCBI chr 3:172,505,508...172,523,430
Ensembl chr 3:172,505,508...172,523,475
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TNNT1
troponin T1, slow skeletal type
decreases expression
EXP
Zearalenone results in decreased expression of TNNT1 mRNA
CTD
PMID:19371625
NCBI chr19:55,132,698...55,149,206
Ensembl chr19:55,132,698...55,149,206
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TOMM40
translocase of outer mitochondrial membrane 40
increases expression
ISO
Zearalenone results in increased expression of TOMM40 protein
CTD
PMID:25058043
NCBI chr19:44,891,254...44,903,689
Ensembl chr19:44,890,569...44,903,689
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TOMM70
translocase of outer mitochondrial membrane 70
increases expression
ISO
Zearalenone results in increased expression of TOMM70A protein
CTD
PMID:25058043
NCBI chr 3:100,363,431...100,401,089
Ensembl chr 3:100,363,431...100,401,089
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TP53
tumor protein p53
decreases expression multiple interactions increases expression
ISO EXP
Zearalenone results in decreased expression of TRP53 mRNA; Zearalenone results in decreased expression of TRP53 protein [Zearalenone co-treated with Aflatoxin B1] promotes the reaction [deoxynivalenol results in increased expression of TP53 mRNA] Zearalenone results in increased expression of TP53 mRNA Zearalenone results in increased expression of TRP53 protein crocin inhibits the reaction [Zearalenone results in increased expression of TRP53 protein]
CTD
PMID:24412631 PMID:26231423 PMID:27473017 PMID:30668976
NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,546
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TP73
tumor protein p73
multiple interactions
EXP
[Zearalenone co-treated with Aflatoxin B1] results in increased expression of TP73 mRNA
CTD
PMID:28965971
NCBI chr 1:3,652,516...3,736,201
Ensembl chr 1:3,652,516...3,736,201
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TPI1
triosephosphate isomerase 1
decreases expression
ISO
Zearalenone results in decreased expression of TPI1 protein
CTD
PMID:36252740
NCBI chr12:6,867,420...6,870,948
Ensembl chr12:6,867,119...6,870,948
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TPMT
thiopurine S-methyltransferase
decreases expression
ISO
Zearalenone results in decreased expression of TPMT protein
CTD
PMID:36252740
NCBI chr 6:18,128,311...18,155,169
Ensembl chr 6:18,128,311...18,155,077
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TPT1
tumor protein, translationally-controlled 1
decreases expression
ISO
Zearalenone results in decreased expression of TPT1 protein
CTD
PMID:36252740
NCBI chr13:45,333,471...45,341,183
Ensembl chr13:45,333,471...45,341,284
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TRAP1
TNF receptor associated protein 1
increases expression
ISO
Zearalenone results in increased expression of TRAP1 protein
CTD
PMID:25058043
NCBI chr16:3,658,037...3,717,524
Ensembl chr16:3,651,639...3,717,553
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TRAPPC3L
trafficking protein particle complex subunit 3L
increases expression
EXP
Zearalenone results in increased expression of TRAPPC3L mRNA
CTD
PMID:36828454
NCBI chr 6:116,494,989...116,545,684
Ensembl chr 6:116,494,989...116,545,684
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TSC22D1
TSC22 domain family member 1
decreases expression
EXP
Zearalenone results in decreased expression of TSC22D1 mRNA
CTD
PMID:19371625
NCBI chr13:44,432,143...44,577,344
Ensembl chr13:44,432,143...44,577,147
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TSEN2
tRNA splicing endonuclease subunit 2
increases expression
EXP
Zearalenone results in increased expression of TSEN2 mRNA
CTD
PMID:36828454
NCBI chr 3:12,480,231...12,539,624
Ensembl chr 3:12,484,421...12,541,549
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TSHB
thyroid stimulating hormone subunit beta
multiple interactions decreases expression
ISO
Gallic Acid inhibits the reaction [Zearalenone results in decreased expression of TSHB protein]
CTD
PMID:34723416
NCBI chr 1:115,029,826...115,034,309
Ensembl chr 1:115,029,826...115,034,302
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TSKU
tsukushi, small leucine rich proteoglycan
increases expression
EXP
Zearalenone results in increased expression of TSKU mRNA
CTD
PMID:19371625
NCBI chr11:76,782,280...76,798,144
Ensembl chr11:76,782,251...76,798,153
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TSPAN1
tetraspanin 1
increases expression
ISO
Zearalenone results in increased expression of TSPAN1 mRNA
CTD
PMID:17557909
NCBI chr 1:46,175,087...46,196,489
Ensembl chr 1:46,175,073...46,185,962
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TSPAN10
tetraspanin 10
decreases expression
EXP
Zearalenone results in decreased expression of TSPAN10 mRNA
CTD
PMID:19371625
NCBI chr17:81,637,196...81,648,755
Ensembl chr17:81,637,171...81,648,754
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TSPAN12
tetraspanin 12
decreases expression
EXP
Zearalenone results in decreased expression of TSPAN12 mRNA
CTD
PMID:19371625
NCBI chr 7:120,787,320...120,858,335
Ensembl chr 7:120,787,320...120,858,402
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TST
thiosulfate sulfurtransferase
decreases expression
ISO
Zearalenone results in decreased expression of TST mRNA
CTD
PMID:30138655
NCBI chr22:37,010,859...37,020,183
Ensembl chr22:37,010,859...37,020,183
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TUBA1A
tubulin alpha 1a
decreases expression
ISO
Zearalenone results in decreased expression of TUBA1A protein
CTD
PMID:36252740
NCBI chr12:49,184,795...49,189,080
Ensembl chr12:49,184,686...49,189,324
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TUBB
tubulin beta class I
decreases expression
ISO
Zearalenone results in decreased expression of TUBB5 protein
CTD
PMID:36252740
NCBI chr 6:30,720,352...30,725,422
Ensembl chr 6:30,717,435...30,725,538
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TUBB4B
tubulin beta 4B class IVb
decreases expression
ISO
Zearalenone results in decreased expression of TUBB4B protein
CTD
PMID:36252740
NCBI chr 9:137,241,287...137,243,707
Ensembl chr 9:137,241,287...137,243,707
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TWIST1
twist family bHLH transcription factor 1
decreases expression
EXP
Zearalenone results in decreased expression of TWIST1 mRNA
CTD
PMID:28965971
NCBI chr 7:19,113,047...19,117,636
Ensembl chr 7:19,020,991...19,117,636
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TXN
thioredoxin
decreases expression
ISO
Zearalenone results in decreased expression of TXN1 protein
CTD
PMID:36252740
NCBI chr 9:110,243,810...110,256,507
Ensembl chr 9:110,243,810...110,256,507
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TXNIP
thioredoxin interacting protein
multiple interactions
EXP
[Plant Extracts co-treated with ochratoxin A co-treated with Zearalenone] results in increased expression of TXNIP mRNA; [Plant Extracts co-treated with Zearalenone] results in increased expression of TXNIP mRNA; [Zearalenone co-treated with ochratoxin A] results in increased expression of TXNIP mRNA
CTD
PMID:34015425
NCBI chr 1:145,992,435...145,996,579
Ensembl chr 1:145,992,435...145,996,579
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UBA1
ubiquitin like modifier activating enzyme 1
decreases expression
ISO
Zearalenone results in decreased expression of UBA1 protein
CTD
PMID:36252740
NCBI chr X:47,190,847...47,215,128
Ensembl chr X:47,190,861...47,215,128
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UBA5
ubiquitin like modifier activating enzyme 5
decreases expression
ISO
Zearalenone results in decreased expression of UBA5 protein
CTD
PMID:36252740
NCBI chr 3:132,654,430...132,679,794
Ensembl chr 3:132,654,446...132,679,794
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UCHL1
ubiquitin C-terminal hydrolase L1
decreases expression
ISO
Zearalenone results in decreased expression of UCHL1 protein
CTD
PMID:36252740
NCBI chr 4:41,256,928...41,268,455
Ensembl chr 4:41,256,413...41,268,455
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UCP2
uncoupling protein 2
multiple interactions increases expression
EXP ISO
[Plant Extracts co-treated with ochratoxin A co-treated with Zearalenone co-treated with beauvericin] results in decreased expression of UCP2 mRNA; [Plant Extracts co-treated with ochratoxin A co-treated with Zearalenone] results in increased expression of UCP2 mRNA; [Plant Extracts co-treated with Zearalenone] results in increased expression of UCP2 mRNA Nicotinamide Mononucleotide inhibits the reaction [Zearalenone results in increased expression of UCP2 mRNA]
CTD
PMID:34015425 PMID:38159578
NCBI chr11:73,974,672...73,983,202
Ensembl chr11:73,974,061...73,982,843
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UGT1A1
UDP glucuronosyltransferase family 1 member A1
increases glucuronidation
EXP
UGT1A1 protein results in increased glucuronidation of Zearalenone
CTD
PMID:14557274
NCBI chr 2:233,760,270...233,773,300
Ensembl chr 2:233,760,270...233,773,300
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UGT1A10
UDP glucuronosyltransferase family 1 member A10
increases glucuronidation
EXP
UGT1A10 protein results in increased glucuronidation of Zearalenone
CTD
PMID:14557274
NCBI chr 2:233,636,448...233,773,300
Ensembl chr 2:233,636,448...233,773,300
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UGT1A7
UDP glucuronosyltransferase family 1 member A7
increases glucuronidation
EXP
UGT1A7 protein results in increased glucuronidation of Zearalenone
CTD
PMID:14557274
NCBI chr 2:233,681,901...233,773,300
Ensembl chr 2:233,681,901...233,773,300
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UGT1A8
UDP glucuronosyltransferase family 1 member A8
increases glucuronidation
EXP
UGT1A8 protein results in increased glucuronidation of Zearalenone
CTD
PMID:14557274
NCBI chr 2:233,617,633...233,773,300
Ensembl chr 2:233,617,633...233,773,300
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UGT1A9
UDP glucuronosyltransferase family 1 member A9
increases glucuronidation
EXP
UGT1A9 protein results in increased glucuronidation of Zearalenone
CTD
PMID:14557274
NCBI chr 2:233,671,898...233,773,300
Ensembl chr 2:233,671,898...233,773,300
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UNC5B-AS1
UNC5B antisense RNA 1
decreases expression
EXP
Zearalenone results in decreased expression of UNC5B-AS1 mRNA
CTD
PMID:36828454
NCBI chr10:71,217,224...71,218,228
Ensembl chr10:71,217,219...71,218,308
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UQCRC2
ubiquinol-cytochrome c reductase core protein 2
increases expression
ISO
Zearalenone results in increased expression of UQCRC2 protein
CTD
PMID:25058043
NCBI chr16:21,953,361...21,983,660
Ensembl chr16:21,953,288...21,983,660
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USP5
ubiquitin specific peptidase 5
decreases expression
ISO
Zearalenone results in decreased expression of USP5 protein
CTD
PMID:36252740
NCBI chr12:6,852,150...6,866,632
Ensembl chr12:6,852,148...6,866,632
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UTP15
UTP15 small subunit processome component
increases expression
EXP
Zearalenone results in increased expression of UTP15 mRNA
CTD
PMID:19371625
NCBI chr 5:73,565,741...73,583,380
Ensembl chr 5:73,565,443...73,583,380
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VAT1
vesicle amine transport 1
increases expression
ISO
Zearalenone results in increased expression of VAT1 protein
CTD
PMID:25058043
NCBI chr17:43,014,607...43,022,385
Ensembl chr17:43,014,607...43,025,123
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VCL
vinculin
decreases expression
ISO
Zearalenone results in decreased expression of VCL protein
CTD
PMID:36288102
NCBI chr10:73,998,116...74,121,363
Ensembl chr10:73,995,193...74,121,363
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VCPKMT
valosin containing protein lysine methyltransferase
decreases expression
EXP
Zearalenone results in decreased expression of VCPKMT mRNA
CTD
PMID:19371625
NCBI chr14:50,102,716...50,116,572
Ensembl chr14:50,108,632...50,116,600
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VDAC1
voltage dependent anion channel 1
increases expression
ISO
Zearalenone results in increased expression of VDAC1 protein
CTD
PMID:34716709
NCBI chr 5:133,971,871...134,114,540
Ensembl chr 5:133,971,871...134,004,975
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VEGFA
vascular endothelial growth factor A
decreases expression increases expression
ISO EXP
Zearalenone results in decreased expression of VEGFA mRNA Zearalenone results in increased expression of VEGFA mRNA
CTD
PMID:24412631 PMID:27757495
NCBI chr 6:43,770,211...43,786,487
Ensembl chr 6:43,770,184...43,786,487
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VLDLR
very low density lipoprotein receptor
increases expression
EXP
Zearalenone results in increased expression of VLDLR mRNA
CTD
PMID:25424538
NCBI chr 9:2,621,787...2,660,056
Ensembl chr 9:2,621,182...2,660,056
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VPREB1
V-set pre-B cell surrogate light chain 1
decreases expression
EXP
Zearalenone results in decreased expression of VPREB1 mRNA
CTD
PMID:25424538
NCBI chr22:22,244,786...22,245,515
Ensembl chr22:22,244,780...22,245,515
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WEE1
WEE1 G2 checkpoint kinase
increases expression
ISO
Zearalenone results in increased expression of WEE1 protein
CTD
PMID:35504548
NCBI chr11:9,573,670...9,589,985
Ensembl chr11:9,573,670...9,593,457
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WNT3
Wnt family member 3
decreases expression
ISO
Zearalenone results in decreased expression of WNT3 protein
CTD
PMID:36288102
NCBI chr17:46,762,506...46,818,692
Ensembl chr17:46,762,506...46,833,154
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WNT7A
Wnt family member 7A
decreases expression
EXP
Zearalenone results in decreased expression of WNT7A mRNA
CTD
PMID:16534752
NCBI chr 3:13,816,258...13,880,071
Ensembl chr 3:13,816,258...13,880,071
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WT1
WT1 transcription factor
decreases expression
ISO
Zearalenone results in decreased expression of WT1 mRNA
CTD
PMID:24412631
NCBI chr11:32,387,775...32,435,539
Ensembl chr11:32,387,775...32,435,564
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WWP2
WW domain containing E3 ubiquitin protein ligase 2
decreases expression
EXP
Zearalenone results in decreased expression of WWP2 mRNA
CTD
PMID:19371625
NCBI chr16:69,762,332...69,941,739
Ensembl chr16:69,762,328...69,941,741
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WWTR1
WW domain containing transcription regulator 1
increases expression
ISO
Zearalenone results in increased expression of WWTR1 mRNA; Zearalenone results in increased expression of WWTR1 protein
CTD
PMID:30138655
NCBI chr 3:149,517,235...149,724,788
Ensembl chr 3:149,517,235...149,736,714
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XBP1
X-box binding protein 1
increases expression
EXP
Zearalenone results in increased expression of XBP1 mRNA
CTD
PMID:28965971
NCBI chr22:28,794,560...28,800,569
Ensembl chr22:28,794,555...28,800,597
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XDH
xanthine dehydrogenase
increases activity multiple interactions
ISO
Zearalenone results in increased activity of XDH protein Gallic Acid inhibits the reaction [Zearalenone results in increased activity of XDH protein]
CTD
PMID:34723416
NCBI chr 2:31,334,321...31,414,742
Ensembl chr 2:31,334,321...31,414,742
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YAP1
Yes1 associated transcriptional regulator
increases phosphorylation increases expression
ISO
Zearalenone results in increased phosphorylation of YAP1 protein Zearalenone results in increased expression of YAP1 mRNA
CTD
PMID:30138655
NCBI chr11:102,110,447...102,233,424
Ensembl chr11:102,110,447...102,233,424
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YKT6
YKT6 v-SNARE homolog
multiple interactions
ISO
[Zearalenone co-treated with CGA protein] results in increased expression of YKT6 protein
CTD
PMID:25058043
NCBI chr 7:44,200,978...44,214,294
Ensembl chr 7:44,200,959...44,214,294
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ZKSCAN2
zinc finger with KRAB and SCAN domains 2
increases expression
EXP
Zearalenone results in increased expression of ZKSCAN2 mRNA
CTD
PMID:19371625
NCBI chr16:25,236,001...25,257,845
Ensembl chr16:25,236,001...25,257,845
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ZMYM3
zinc finger MYM-type containing 3
increases expression
EXP
Zearalenone results in increased expression of ZMYM3 mRNA
CTD
PMID:19371625
NCBI chr X:71,239,624...71,255,290
Ensembl chr X:71,239,624...71,255,146
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ZMYND10
zinc finger MYND-type containing 10
decreases expression
EXP
Zearalenone results in decreased expression of ZMYND10 mRNA
CTD
PMID:19371625
NCBI chr 3:50,341,112...50,345,732
Ensembl chr 3:50,341,110...50,345,732
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ZNF239
zinc finger protein 239
increases expression
EXP
Zearalenone results in increased expression of ZNF239 mRNA
CTD
PMID:36828454
NCBI chr10:43,556,344...43,574,616
Ensembl chr10:43,556,344...43,574,618
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ZNF485
zinc finger protein 485
increases expression
EXP
Zearalenone results in increased expression of ZNF485 mRNA
CTD
PMID:36828454
NCBI chr10:43,606,438...43,617,904
Ensembl chr10:43,606,419...43,617,904
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