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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:zearalenone
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Accession:CHEBI:10106 term browser browse the term
Definition:A macrolide comprising a fourteen-membered lactone fused to 1,3-dihydroxybenzene; a potent estrogenic metabolite produced by some Giberella species.
Synonyms:exact_synonym: (3S,11E)-14,16-dihydroxy-3-methyl-3,4,5,6,9,10-hexahydro-1H-2-benzoxacyclotetradecine-1,7(8H)-dione
 related_synonym: (10S)-Zearalenone;   (S)-Zearalenone;   (S-(E))-3,4,5,6,9,10-Hexahydro-14,16-dihydroxy-3-methyl-1H-2-benzoxacyclotetradecin-1,7(8H)-dione;   6-(10-Hydroxy-6-oxo-trans-1-undecenyl)-beta-resorcylic acid lactone;   Formula=C18H22O5;   InChI=1S/C18H22O5/c1-12-6-5-9-14(19)8-4-2-3-7-13-10-15(20)11-16(21)17(13)18(22)23-12/h3,7,10-12,20-21H,2,4-6,8-9H2,1H3/b7-3+/t12-/m0/s1;   InChIKey=MBMQEIFVQACCCH-QBODLPLBSA-N;   SMILES=C[C@H]1CCCC(=O)CCC\\C=C\\c2cc(O)cc(O)c2C(=O)O1;   trans-Zearalenone
 xref: CAS:17924-92-4;   KEGG:C09981;   KNApSAcK:C00003025;   LIPID_MAPS_instance:LMPK04000016
 xref_mesh: MESH:D015025
 xref: PMID:17339071;   PMID:18027362;   PMID:18221829;   PMID:18280460;   PMID:18692541;   PMID:20654554;   Reaxys:4875541


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zearalenone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aars1 alanyl-tRNA synthetase 1 decreases expression ISO Zearalenone results in decreased expression of AARS protein CTD PMID:25058043 NCBI chr19:43,193,264...43,215,281
Ensembl chr19:43,193,257...43,215,281
JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions
affects expression
decreases expression
increases expression
EXP fulvestrant inhibits the reaction [Zearalenone results in increased expression of ABCB1A mRNA]
Zearalenone affects the expression of ABCB1A protein
Zearalenone results in decreased expression of ABCB1A mRNA
Zearalenone results in increased expression of ABCB1 mRNA; Zearalenone results in increased expression of ABCB1A mRNA
CTD PMID:20607812 PMID:22521637 PMID:23707492 PMID:29627501 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcb1b ATP-binding cassette, subfamily B (MDR/TAP), member 1B decreases expression
increases expression
EXP Zearalenone results in decreased expression of ABCB1B mRNA
Zearalenone results in increased expression of ABCB1B mRNA; Zearalenone results in increased expression of ABCB1B protein
CTD PMID:22521637 PMID:23707492 NCBI chr 4:22,225,123...22,307,577
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 increases expression
decreases expression
affects expression
multiple interactions
increases transport
ISO
EXP
Zearalenone results in increased expression of ABCC1 protein
Zearalenone results in decreased expression of ABCC1 mRNA; Zearalenone results in decreased expression of ABCC1 protein
Zearalenone affects the expression of ABCC1 mRNA; Zearalenone affects the expression of ABCC1 protein
verlukast inhibits the reaction [ABCC1 protein results in increased transport of Zearalenone]; Zearalenone inhibits the reaction [ABCC1 protein results in increased transport of calcein AM]
CTD PMID:19580841 PMID:19647055 PMID:22521637 PMID:23707492 NCBI chr10:549,537...672,235
Ensembl chr10:549,883...672,196
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 increases expression
increases transport
multiple interactions
ISO Zearalenone results in increased expression of ABCC2 mRNA
ABCC2 protein results in increased transport of Zearalenone
verlukast inhibits the reaction [ABCC2 protein results in increased transport of Zearalenone]; Zearalenone inhibits the reaction [ABCC2 protein results in increased transport of calcein AM]
CTD PMID:19580841 PMID:19647055 NCBI chr 1:263,554,426...263,612,556
Ensembl chr 1:263,554,453...263,613,252
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 decreases expression
affects expression
multiple interactions
ISO
EXP
Zearalenone results in decreased expression of ABCC3 mRNA
Zearalenone affects the expression of ABCC3 mRNA; Zearalenone affects the expression of ABCC3 protein
Zearalenone inhibits the reaction [ABCC3 protein results in increased transport of calcein AM]
CTD PMID:19371625 PMID:19647055 PMID:22521637 NCBI chr10:82,047,308...82,116,928
Ensembl chr10:82,047,863...82,117,109
JBrowse link
G Abcc4 ATP binding cassette subfamily C member 4 multiple interactions
increases expression
decreases expression
EXP fulvestrant inhibits the reaction [Zearalenone results in increased expression of ABCC4 mRNA]
Zearalenone results in increased expression of ABCC4 mRNA; Zearalenone results in increased expression of ABCC4 protein
Zearalenone results in decreased expression of ABCC4 protein
CTD PMID:23707492 NCBI chr15:103,695,415...103,927,980
Ensembl chr15:103,696,557...103,927,592
JBrowse link
G Abcc5 ATP binding cassette subfamily C member 5 multiple interactions
decreases expression
increases expression
affects expression
EXP fulvestrant inhibits the reaction [Zearalenone results in increased expression of ABCC5 mRNA]
Zearalenone results in decreased expression of ABCC5 mRNA
Zearalenone affects the expression of ABCC5 protein
CTD PMID:23707492 PMID:29627501 NCBI chr11:84,395,982...84,490,215
Ensembl chr11:84,396,033...84,490,211
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 increases expression
increases transport
decreases expression
ISO
EXP
Zearalenone results in increased expression of ABCG2 mRNA
ABCG2 protein results in increased transport of Zearalenone
Zearalenone results in decreased expression of ABCG2 mRNA; Zearalenone results in decreased expression of ABCG2 protein
Zearalenone results in increased expression of ABCG2 mRNA; Zearalenone results in increased expression of ABCG2 protein
CTD PMID:19580841 PMID:22521637 PMID:23707492 PMID:30576553 NCBI chr 4:88,765,441...88,890,268
Ensembl chr 4:88,832,178...88,890,621
JBrowse link
G Acat2 acetyl-CoA acetyltransferase 2 decreases expression ISO Zearalenone results in decreased expression of ACAT2 protein CTD PMID:25058043 NCBI chr 1:47,972,399...47,992,654
Ensembl chr 1:47,972,399...47,992,653
JBrowse link
G Ackr2 atypical chemokine receptor 2 decreases expression ISO Zearalenone results in decreased expression of ACKR2 mRNA CTD PMID:19371625 NCBI chr 8:130,526,521...130,543,566
Ensembl chr 8:130,538,651...130,542,227
JBrowse link
G Acsf2 acyl-CoA synthetase family member 2 increases expression ISO Zearalenone results in increased expression of ACSF2 protein CTD PMID:25058043 NCBI chr10:82,284,719...82,326,771
Ensembl chr10:82,284,720...82,326,771
JBrowse link
G Actr3 actin related protein 3 multiple interactions ISO [Zearalenone co-treated with CGA protein] results in increased expression of ACTR3 protein CTD PMID:25058043 NCBI chr13:41,695,520...41,738,622
Ensembl chr13:41,695,183...41,738,658
JBrowse link
G Adamts9 ADAM metallopeptidase with thrombospondin type 1 motif, 9 increases expression
decreases expression
ISO
EXP
Zearalenone results in increased expression of ADAMTS9 mRNA
Zearalenone results in decreased expression of ADAMTS9 mRNA
CTD PMID:17557909 PMID:19371625 NCBI chr 4:124,660,254...124,860,997
Ensembl chr 4:124,660,262...124,858,250
JBrowse link
G Adh7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide decreases expression ISO Zearalenone results in decreased expression of ADH7 protein CTD PMID:25058043 NCBI chr 2:243,500,540...243,516,865
Ensembl chr 2:243,502,073...243,516,532
JBrowse link
G Ahr aryl hydrocarbon receptor increases expression ISO Zearalenone results in increased expression of AHR mRNA CTD PMID:32119988 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Ahsa1 activator of Hsp90 ATPase activity 1 multiple interactions ISO [Zearalenone co-treated with CGA protein] results in increased expression of AHSA1 protein CTD PMID:25058043 NCBI chr 6:111,296,168...111,304,224
Ensembl chr 6:111,296,417...111,304,224
JBrowse link
G Aicda activation-induced cytidine deaminase increases expression ISO Zearalenone results in increased expression of AICDA mRNA CTD PMID:27757495 NCBI chr 4:155,359,909...155,371,104
Ensembl chr 4:155,359,921...155,369,671
JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 increases expression ISO Zearalenone results in increased expression of AIFM1 protein CTD PMID:25058043 NCBI chr  X:135,304,063...135,343,062
Ensembl chr  X:135,304,066...135,343,087
JBrowse link
G Akr1b8 aldo-keto reductase family 1, member B8 decreases activity
decreases expression
EXP
ISO
Zearalenone results in decreased activity of AKR1B8 protein
Zearalenone results in decreased expression of AKR1B8 protein
CTD PMID:18845131 PMID:25058043 NCBI chr 4:61,772,064...61,784,637
Ensembl chr 4:61,771,970...61,828,657
JBrowse link
G Akt1 AKT serine/threonine kinase 1 decreases expression
increases expression
ISO Zearalenone results in decreased expression of AKT1 protein
Zearalenone results in increased expression of AKT1 mRNA
CTD PMID:31419471 PMID:32119988 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Akt3 AKT serine/threonine kinase 3 decreases expression ISO Zearalenone results in decreased expression of AKT3 mRNA CTD PMID:30717214 NCBI chr13:95,076,308...95,348,913
Ensembl chr13:95,081,390...95,348,913
JBrowse link
G Alad aminolevulinate dehydratase multiple interactions
decreases activity
ISO lycopene inhibits the reaction [Zearalenone results in decreased activity of ALAD protein] CTD PMID:25682699 NCBI chr 5:78,368,867...78,379,206
Ensembl chr 5:78,368,867...78,379,346
JBrowse link
G Alb albumin affects expression
multiple interactions
ISO Zearalenone affects the expression of ALB mRNA
[deoxynivalenol co-treated with Zearalenone] affects the expression of ALB mRNA; [deoxynivalenol co-treated with Zearalenone] results in decreased expression of ALB protein; [deoxynivalenol co-treated with Zearalenone] results in increased expression of ALB mRNA
CTD PMID:28865950 PMID:28935499 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
JBrowse link
G Aldob aldolase, fructose-bisphosphate B multiple interactions
increases expression
ISO [deoxynivalenol co-treated with Zearalenone] affects the expression of ALDOB mRNA; [deoxynivalenol co-treated with Zearalenone] results in increased expression of ALDOB mRNA
Zearalenone results in increased expression of ALDOB mRNA
CTD PMID:28865950 PMID:28935499 NCBI chr 5:64,805,772...64,818,813
Ensembl chr 5:64,805,773...64,818,824
JBrowse link
G Aldoc aldolase, fructose-bisphosphate C decreases expression ISO Zearalenone results in decreased expression of ALDOC protein CTD PMID:25058043 NCBI chr10:65,586,504...65,590,093
Ensembl chr10:65,586,504...65,590,126
JBrowse link
G Alpg alkaline phosphatase, germ cell increases expression ISO Zearalenone results in increased expression of ALPG mRNA CTD PMID:19371625 NCBI chr 9:94,164,667...94,184,972
Ensembl chr 9:94,178,221...94,181,010
JBrowse link
G Alpl alkaline phosphatase, biomineralization associated multiple interactions ISO [Zearalenone binds to ESR1 protein] which results in increased activity of ALPL protein; fulvestrant inhibits the reaction [[Zearalenone binds to ESR1 protein] which results in increased activity of ALPL protein] CTD PMID:12650720 NCBI chr 5:156,086,496...156,141,513
Ensembl chr 5:156,086,497...156,141,537
JBrowse link
G Anapc1 anaphase promoting complex subunit 1 increases expression ISO Zearalenone results in increased expression of ANAPC1 mRNA CTD PMID:19371625 NCBI chr 3:121,147,484...121,226,125
Ensembl chr 3:121,147,547...121,226,125
JBrowse link
G Ano1 anoctamin 1 increases expression ISO Zearalenone results in increased expression of ANO1 mRNA CTD PMID:19371625 NCBI chr 1:217,754,349...217,902,540
Ensembl chr 1:217,754,336...217,902,473
JBrowse link
G Anxa3 annexin A3 decreases expression ISO Zearalenone results in decreased expression of ANXA3 protein CTD PMID:25058043 NCBI chr14:14,371,921...14,426,503
Ensembl chr14:14,364,008...14,426,437
JBrowse link
G Anxa5 annexin A5 affects binding ISO Zearalenone binds to ANXA5 protein CTD PMID:24412631 NCBI chr 2:123,162,477...123,194,730
Ensembl chr 2:123,162,461...123,193,130
JBrowse link
G Anxa7 annexin A7 decreases expression ISO Zearalenone results in decreased expression of ANXA7 protein CTD PMID:25058043 NCBI chr15:4,254,470...4,281,296
Ensembl chr15:4,254,499...4,281,287
JBrowse link
G Apln apelin decreases expression EXP Zearalenone results in decreased expression of APLN mRNA CTD PMID:17557909 NCBI chr  X:134,856,719...134,866,210
Ensembl chr  X:134,856,726...134,866,210
JBrowse link
G Apobec1 apolipoprotein B mRNA editing enzyme catalytic subunit 1 increases expression EXP Zearalenone results in increased expression of APOBEC1 mRNA CTD PMID:17557909 NCBI chr 4:155,386,367...155,414,034
Ensembl chr 4:155,386,711...155,401,480
JBrowse link
G Apoe apolipoprotein E decreases expression ISO Zearalenone results in decreased expression of APOE mRNA CTD PMID:19371625 NCBI chr 1:80,612,894...80,616,820
Ensembl chr 1:80,612,895...80,617,057
JBrowse link
G Ar androgen receptor multiple interactions
decreases activity
decreases expression
ISO [15-acetyldeoxynivalenol co-treated with 3-acetyldeoxynivalenol co-treated with deoxynivalenol co-treated with zearalenol co-treated with Zearalenone] results in decreased activity of AR protein; Zearalenone inhibits the reaction [Metribolone results in increased activity of AR protein]; Zearalenone inhibits the reaction [Testosterone binds to and results in increased activity of AR protein]
Zearalenone metabolite results in decreased activity of AR protein; Zearalenone results in decreased activity of AR protein
Zearalenone results in decreased expression of AR mRNA
CTD PMID:18324785 PMID:21803136 PMID:24412631 PMID:25455890 PMID:27481073 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Arnt aryl hydrocarbon receptor nuclear translocator increases expression EXP Zearalenone results in increased expression of ARNT mRNA CTD PMID:20607812 NCBI chr 2:196,594,178...196,651,486
Ensembl chr 2:196,594,303...196,651,179
JBrowse link
G Asah1 N-acylsphingosine amidohydrolase 1 decreases expression ISO Zearalenone results in decreased expression of ASAH1 mRNA CTD PMID:19371625 NCBI chr16:53,998,604...54,030,006
Ensembl chr16:53,998,560...54,040,836
JBrowse link
G Asrgl1 asparaginase and isoaspartyl peptidase 1 increases expression ISO Zearalenone results in increased expression of ASRGL1 mRNA CTD PMID:19371625 NCBI chr 1:225,309,737...225,329,743
Ensembl chr 1:225,309,246...225,329,770
JBrowse link
G Atm ATM serine/threonine kinase increases expression
decreases expression
ISO Zearalenone results in increased expression of ATM mRNA
Zearalenone results in decreased expression of ATM mRNA; Zearalenone results in decreased expression of ATM protein
CTD PMID:27862621 PMID:29758222 NCBI chr 8:58,015,938...58,119,973
Ensembl chr 8:58,015,940...58,120,045
JBrowse link
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 multiple interactions ISO [Zearalenone co-treated with CGA protein] results in decreased expression of ATP1A1 protein CTD PMID:25058043 NCBI chr 2:204,003,742...204,032,023
Ensembl chr 2:204,003,742...204,032,023
JBrowse link
G Atp5pb ATP synthase peripheral stalk-membrane subunit b increases expression ISO Zearalenone results in increased expression of ATP5PB protein CTD PMID:25058043 NCBI chr 2:208,566,385...208,577,147
Ensembl chr 2:208,566,385...208,577,146
JBrowse link
G Atpaf1 ATP synthase mitochondrial F1 complex assembly factor 1 decreases expression ISO Zearalenone results in decreased expression of ATPAF1 mRNA CTD PMID:19371625 NCBI chr 5:134,641,618...134,667,079
Ensembl chr 5:134,641,608...134,667,084
JBrowse link
G Bax BCL2 associated X, apoptosis regulator affects localization
multiple interactions
increases expression
ISO
EXP
Zearalenone affects the localization of BAX protein
Aflatoxin B1 inhibits the reaction [Zearalenone results in increased expression of BAX mRNA]; deoxynivalenol promotes the reaction [Zearalenone results in increased expression of BAX mRNA]
Zearalenone results in increased expression of BAX; Zearalenone results in increased expression of BAX mRNA; Zearalenone results in increased expression of BAX protein
CTD PMID:19541794 PMID:21767629 PMID:24530352 PMID:25445755 PMID:28089945 PMID:30600648 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression
increases expression
ISO
EXP
Zearalenone results in decreased expression of BCL2 mRNA; Zearalenone results in decreased expression of BCL2 protein
Zearalenone results in increased expression of BCL2 mRNA
CTD PMID:21767629 PMID:24412631 PMID:28089945 PMID:28965971 PMID:30600648 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bdnf brain-derived neurotrophic factor decreases expression ISO Zearalenone results in decreased expression of BDNF mRNA CTD PMID:24412706 NCBI chr 3:100,768,637...100,819,216
Ensembl chr 3:100,768,637...100,819,210
JBrowse link
G Becn1 beclin 1 increases expression
multiple interactions
EXP
ISO
Zearalenone results in increased expression of BECN1
acadesine promotes the reaction [Zearalenone results in increased expression of BECN1 protein]
CTD PMID:24530352 PMID:31982503 NCBI chr10:89,209,944...89,225,297
Ensembl chr10:89,209,940...89,225,297
JBrowse link
G Bicd1 BICD cargo adaptor 1 increases expression ISO Zearalenone results in increased expression of BICD1 mRNA CTD PMID:19371625 NCBI chr 4:184,018,845...184,167,628
Ensembl chr 4:184,019,087...184,165,540
JBrowse link
G Bid BH3 interacting domain death agonist increases activity
multiple interactions
EXP Zearalenone results in increased activity of BID protein
benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [Zearalenone results in increased activity of BID protein]
CTD PMID:30600648 NCBI chr 4:153,439,812...153,465,247
Ensembl chr 4:153,442,218...153,465,203
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 increases expression ISO Zearalenone results in increased expression of BIRC5 mRNA CTD PMID:28965971 NCBI chr10:106,856,097...106,864,419
Ensembl chr10:106,856,097...106,864,413
JBrowse link
G Bnip1 BCL2 interacting protein 1 increases expression ISO Zearalenone results in increased expression of BNIP1 mRNA CTD PMID:19371625 NCBI chr10:16,677,077...16,689,321
Ensembl chr10:16,677,077...16,689,321
JBrowse link
G Braf B-Raf proto-oncogene, serine/threonine kinase increases expression ISO Zearalenone results in increased expression of BRAF protein CTD PMID:29758222 NCBI chr 4:67,389,331...67,520,549
Ensembl chr 4:67,396,192...67,520,356
JBrowse link
G Brca1 BRCA1, DNA repair associated increases expression ISO Zearalenone results in increased expression of BRCA1 mRNA CTD PMID:28552778 PMID:28965971 NCBI chr10:89,394,821...89,455,093
Ensembl chr10:89,394,803...89,454,681
JBrowse link
G C3 complement C3 increases expression EXP Zearalenone results in increased expression of C3 mRNA CTD PMID:17557909 NCBI chr 9:9,721,137...9,747,084
Ensembl chr 9:9,721,105...9,747,167
JBrowse link
G Cables1 Cdk5 and Abl enzyme substrate 1 increases expression ISO Zearalenone results in increased expression of CABLES1 mRNA CTD PMID:19371625 NCBI chr18:3,317,724...3,421,721
Ensembl chr18:3,317,724...3,421,721
JBrowse link
G Calr calreticulin multiple interactions ISO [Zearalenone co-treated with CGA protein] results in decreased expression of CALR protein CTD PMID:25058043 NCBI chr19:25,956,771...25,961,666
Ensembl chr19:25,956,771...25,961,666
JBrowse link
G Camkk2 calcium/calmodulin-dependent protein kinase kinase 2 increases phosphorylation
multiple interactions
ISO Zearalenone results in increased phosphorylation of CAMKK2 protein
2-aminoethyl diphenylborinate inhibits the reaction [Zearalenone results in increased phosphorylation of CAMKK2 protein]; STO 609 inhibits the reaction [Zearalenone results in increased phosphorylation of CAMKK2 protein]
CTD PMID:31982503 NCBI chr12:39,253,409...39,302,601
Ensembl chr12:39,253,409...39,302,601
JBrowse link
G Capn9 calpain 9 increases expression ISO Zearalenone results in increased expression of CAPN9 mRNA CTD PMID:19371625 NCBI chr19:57,341,938...57,378,901
Ensembl chr19:57,341,938...57,378,901
JBrowse link
G Car2 carbonic anhydrase 2 increases expression ISO Zearalenone results in increased expression of CA2 mRNA CTD PMID:19371625 NCBI chr 2:88,097,740...88,112,868
Ensembl chr 2:88,097,720...88,113,029
JBrowse link
G Cars cysteinyl-tRNA synthetase increases expression ISO Zearalenone results in increased expression of CARS1 mRNA CTD PMID:19371625 NCBI chr 1:216,759,367...216,801,652
Ensembl chr 1:216,759,366...216,801,656
JBrowse link
G Casp1 caspase 1 increases expression
multiple interactions
ISO
EXP
Zearalenone results in increased expression of CASP1 mRNA; Zearalenone results in increased expression of CASP1 protein
3-methyladenine promotes the reaction [[Zearalenone co-treated with Lipopolysaccharides] results in increased expression of CASP1 protein modified form]; [Zearalenone co-treated with Lipopolysaccharides] results in increased expression of CASP1 protein; [Zearalenone co-treated with Lipopolysaccharides] results in increased expression of CASP1 protein modified form; MCC-950 inhibits the reaction [[Zearalenone co-treated with Lipopolysaccharides] results in increased expression of CASP1 protein modified form]; NLRP3 protein promotes the reaction [[Zearalenone co-treated with Lipopolysaccharides] results in increased expression of CASP1 protein modified form]; pyrrolidine dithiocarbamic acid inhibits the reaction [Zearalenone results in increased expression of CASP1 protein modified form]; Sirolimus inhibits the reaction [[Zearalenone co-treated with Lipopolysaccharides] results in increased expression of CASP1 protein modified form]
[Dextran Sulfate co-treated with Zearalenone] results in increased expression of CASP1 mRNA; [Dextran Sulfate co-treated with Zearalenone] results in increased expression of CASP1 protein
CTD PMID:30270565 PMID:31586597 NCBI chr 8:2,605,743...2,614,637
Ensembl chr 8:2,604,962...2,614,631
JBrowse link
G Casp3 caspase 3 increases activity
multiple interactions
increases cleavage
increases expression
ISO
EXP
Zearalenone results in increased activity of CASP3 protein
benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [Zearalenone results in increased cleavage of CASP3 protein]
Zearalenone results in increased expression of CASP3 mRNA
[Zearalenone co-treated with Aflatoxin B1] promotes the reaction [deoxynivalenol results in increased expression of CASP3 mRNA]
Zearalenone results in increased expression of CASP3 protein modified form
HERPUD1 protein promotes the reaction [Zearalenone results in increased expression of CASP3 protein modified form]; Zearalenone promotes the reaction [deoxynivalenol results in increased expression of CASP3 mRNA]
CTD PMID:19541794 PMID:19705349 PMID:24530352 PMID:25445755 PMID:28089945 PMID:30394307 PMID:30600648 PMID:30668976 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp8 caspase 8 increases expression
increases cleavage
multiple interactions
ISO
EXP
Zearalenone results in increased expression of CASP8 mRNA
Zearalenone results in increased cleavage of CASP8 protein
[Aflatoxin B1 co-treated with deoxynivalenol] promotes the reaction [Zearalenone results in increased expression of CASP8 mRNA]; [Zearalenone co-treated with Aflatoxin B1] promotes the reaction [deoxynivalenol results in increased expression of CASP8 mRNA]; [Zearalenone co-treated with deoxynivalenol] promotes the reaction [Aflatoxin B1 results in increased expression of CASP8 mRNA]; Zearalenone promotes the reaction [[Aflatoxin B1 co-treated with deoxynivalenol] results in increased expression of CASP8 mRNA]
CTD PMID:30600648 PMID:30668976 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Casp9 caspase 9 increases activity
multiple interactions
increases cleavage
increases expression
EXP
ISO
Zearalenone results in increased activity of CASP9 protein
benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [Zearalenone results in increased cleavage of CASP9 protein]
Zearalenone results in increased expression of CASP9 mRNA
Zearalenone promotes the reaction [[Aflatoxin B1 co-treated with deoxynivalenol] results in increased expression of CASP9 mRNA]
CTD PMID:24530352 PMID:30600648 PMID:30668976 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Cat catalase increases expression
decreases expression
ISO Zearalenone results in increased expression of CAT mRNA
Zearalenone results in decreased expression of CAT protein
CTD PMID:28089945 PMID:28477956 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Cbfa2t3 CBFA2/RUNX1 partner transcriptional co-repressor 3 increases expression ISO Zearalenone results in increased expression of CBFA2T3 mRNA CTD PMID:19371625 NCBI chr19:55,438,409...55,510,652
Ensembl chr19:55,441,572...55,510,460
JBrowse link
G Ccl21 C-C motif chemokine ligand 21 increases expression ISO Zearalenone results in increased expression of CCL21 mRNA CTD PMID:27757495 NCBI chr 5:58,197,678...58,198,782
Ensembl chr 5:58,197,680...58,198,782
JBrowse link
G Ccl22 C-C motif chemokine ligand 22 increases expression ISO Zearalenone results in increased expression of CCL22 mRNA CTD PMID:27757495 NCBI chr19:10,674,189...10,681,145
Ensembl chr19:10,674,189...10,681,145
JBrowse link
G Ccna1 cyclin A1 decreases expression ISO Zearalenone results in decreased expression of CCNA1 mRNA CTD PMID:24412631 NCBI chr 2:144,456,689...144,503,570
Ensembl chr 2:144,458,153...144,467,912
JBrowse link
G Ccnb1 cyclin B1 decreases expression ISO Zearalenone results in decreased expression of CCNB1 mRNA CTD PMID:27862621 NCBI chr 2:30,782,133...30,791,106
Ensembl chr 2:30,783,915...30,791,221
JBrowse link
G Ccnd1 cyclin D1 decreases expression
increases expression
multiple interactions
ISO Zearalenone results in decreased expression of CCND1 mRNA
Zearalenone results in increased expression of CCND1 mRNA; Zearalenone results in increased expression of CCND1 protein
[Tamoxifen co-treated with Zearalenone] results in increased expression of CCND1 protein
CTD PMID:24412631 PMID:30138655 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Ccnd2 cyclin D2 decreases expression EXP
ISO
Zearalenone results in decreased expression of CCND2 mRNA CTD PMID:17557909 PMID:28965971 NCBI chr 4:159,674,885...159,697,207
Ensembl chr 4:159,674,885...159,697,207
JBrowse link
G Ccne1 cyclin E1 multiple interactions ISO [Zearalenone co-treated with Aflatoxin B1] results in increased expression of CCNE1 mRNA CTD PMID:28965971 NCBI chr 1:94,485,830...94,495,112
Ensembl chr 1:94,485,832...94,494,980
JBrowse link
G Ccr1 C-C motif chemokine receptor 1 increases expression ISO Zearalenone results in increased expression of CCR1 mRNA CTD PMID:27757495 NCBI chr 8:132,996,646...133,002,201
Ensembl chr 8:132,996,649...133,002,201
JBrowse link
G Ccr4 C-C motif chemokine receptor 4 increases expression ISO Zearalenone results in increased expression of CCR4 mRNA CTD PMID:27757495 NCBI chr 8:122,530,152...122,535,959
Ensembl chr 8:122,530,624...122,532,070
JBrowse link
G Cct5 chaperonin containing TCP1 subunit 5 increases expression ISO Zearalenone results in increased expression of CCT5 protein CTD PMID:25058043 NCBI chr 2:84,667,578...84,678,730
Ensembl chr 2:84,667,633...84,678,790
JBrowse link
G Cd274 CD274 molecule increases expression ISO Zearalenone results in increased expression of CD274 mRNA CTD PMID:27757495 NCBI chr 1:247,519,890...247,539,659
Ensembl chr 1:247,519,939...247,537,943
JBrowse link
G Cd36 CD36 molecule multiple interactions ISO [Zearalenone co-treated with CGA protein] results in decreased expression of CD36 protein CTD PMID:25058043 NCBI chr 4:14,150,309...14,191,498
Ensembl chr 4:14,001,761...14,249,749
JBrowse link
G Cd86 CD86 molecule multiple interactions ISO [Lipopolysaccharides co-treated with Zearalenone] results in increased expression of CD86 protein CTD PMID:32328699 NCBI chr11:67,060,305...67,117,990
Ensembl chr11:67,082,193...67,118,795
JBrowse link
G Cdc6 cell division cycle 6 decreases expression ISO Zearalenone results in decreased expression of CDC6 mRNA CTD PMID:27862621 NCBI chr10:86,819,477...86,833,301
Ensembl chr10:86,819,472...86,833,402
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A decreases expression ISO Zearalenone results in decreased expression of CDKN1A mRNA CTD PMID:24412631 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cdkn1c cyclin-dependent kinase inhibitor 1C decreases expression ISO Zearalenone results in decreased expression of CDKN1C mRNA CTD PMID:28965971 NCBI chr 1:216,661,067...216,663,791
Ensembl chr 1:216,661,080...216,663,721
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A decreases expression ISO Zearalenone results in decreased expression of CDKN2A mRNA CTD PMID:28965971 NCBI chr 5:107,823,323...107,832,405
Ensembl chr 5:107,823,330...107,841,175
JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha affects expression
multiple interactions
ISO Zearalenone affects the expression of CEBPA mRNA
[deoxynivalenol co-treated with Zearalenone] results in decreased expression of CEBPA mRNA
CTD PMID:28865950 NCBI chr 1:91,363,492...91,366,164
Ensembl chr 1:91,363,492...91,366,164
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta increases expression ISO Zearalenone results in increased expression of CEBPB mRNA CTD PMID:25424538 NCBI chr 3:164,424,502...164,425,933
Ensembl chr 3:164,424,515...164,425,910
JBrowse link
G Cebpd CCAAT/enhancer binding protein delta increases expression ISO Zearalenone results in increased expression of CEBPD mRNA CTD PMID:19371625 NCBI chr11:89,008,008...89,009,146
Ensembl chr11:89,008,008...89,009,146
JBrowse link
G Cfi complement factor I increases expression EXP Zearalenone results in increased expression of CFI mRNA CTD PMID:17557909 NCBI chr 2:235,264,149...235,305,779
Ensembl chr 2:235,264,219...235,305,781
JBrowse link
G Cga glycoprotein hormones, alpha polypeptide multiple interactions
increases expression
ISO fulvestrant inhibits the reaction [Zearalenone results in increased expression of CGA protein]
[Zearalenone co-treated with CGA protein] results in decreased expression of ATP1A1 protein; [Zearalenone co-treated with CGA protein] results in decreased expression of CALR protein; [Zearalenone co-treated with CGA protein] results in decreased expression of CD36 protein; [Zearalenone co-treated with CGA protein] results in decreased expression of HSD17B11 protein; [Zearalenone co-treated with CGA protein] results in decreased expression of MGLL protein; [Zearalenone co-treated with CGA protein] results in decreased expression of P4HB protein; [Zearalenone co-treated with CGA protein] results in decreased expression of SMPDL3B protein; [Zearalenone co-treated with CGA protein] results in decreased expression of SYAP1 protein; [Zearalenone co-treated with CGA protein] results in increased expression of ACTR3 protein; [Zearalenone co-treated with CGA protein] results in increased expression of AHSA1 protein; [Zearalenone co-treated with CGA protein] results in increased expression of DNM1L protein; [Zearalenone co-treated with CGA protein] results in increased expression of PDCD6IP protein; [Zearalenone co-treated with CGA protein] results in increased expression of PHGDH protein; [Zearalenone co-treated with CGA protein] results in increased expression of TLN1 protein; [Zearalenone co-treated with CGA protein] results in increased expression of YKT6 protein
CTD PMID:19580841 PMID:25058043 NCBI chr 5:50,362,491...50,393,368
Ensembl chr 5:50,381,244...50,393,367
JBrowse link
G Chac1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 increases expression ISO Zearalenone results in increased expression of CHAC1 mRNA CTD PMID:25424538 NCBI chr 3:111,160,205...111,163,425
Ensembl chr 3:111,160,205...111,163,425
JBrowse link
G Chac2 ChaC glutathione specific gamma-glutamylcyclotransferase 2 increases expression ISO Zearalenone results in increased expression of CHAC2 mRNA CTD PMID:19371625 NCBI chr14:115,383,906...115,391,757
Ensembl chr14:115,383,910...115,391,652
JBrowse link
G Chchd3 coiled-coil-helix-coiled-coil-helix domain containing 3 increases expression ISO Zearalenone results in increased expression of CHCHD3 protein CTD PMID:25058043 NCBI chr 4:60,080,536...60,358,592
Ensembl chr 4:60,080,538...60,358,562
JBrowse link
G Cldn1 claudin 1 decreases expression
multiple interactions
ISO Zearalenone results in decreased expression of CLDN1 protein
[deoxynivalenol co-treated with Zearalenone] results in decreased expression of CLDN1 mRNA; [deoxynivalenol co-treated with Zearalenone] results in decreased expression of CLDN1 protein
CTD PMID:28865950 PMID:28935499 NCBI chr11:77,815,216...77,830,373
Ensembl chr11:77,815,181...77,830,416
JBrowse link
G Cnfn cornifelin decreases expression ISO Zearalenone results in decreased expression of CNFN mRNA CTD PMID:19371625 NCBI chr 1:82,234,032...82,236,602
Ensembl chr 1:82,234,032...82,236,179
JBrowse link
G Coro1c coronin 1C increases expression ISO Zearalenone results in increased expression of CORO1C mRNA CTD PMID:19371625 NCBI chr12:48,481,741...48,554,054
Ensembl chr12:48,481,750...48,554,052
JBrowse link
G Cpt2 carnitine palmitoyltransferase 2 increases expression ISO Zearalenone results in increased expression of CPT2 protein CTD PMID:25058043 NCBI chr 5:127,505,646...127,523,016
Ensembl chr 5:127,505,614...127,523,089
JBrowse link
G Csf2 colony stimulating factor 2 increases expression ISO Zearalenone results in increased expression of CSF2 mRNA CTD PMID:27757495 NCBI chr10:39,602,089...39,604,070
Ensembl chr10:39,602,089...39,604,070
JBrowse link
G Cst6 cystatin E/M decreases expression ISO Zearalenone results in decreased expression of CST6 mRNA CTD PMID:28965971 NCBI chr 1:220,727,292...220,729,000
Ensembl chr 1:220,727,292...220,729,000
JBrowse link
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 increases expression ISO Zearalenone results in increased expression of CTLA4 mRNA CTD PMID:27757495 NCBI chr 9:67,699,397...67,706,068
Ensembl chr 9:67,699,379...67,706,065
JBrowse link
G Ctsd cathepsin D increases expression ISO Zearalenone results in increased expression of CTSD mRNA CTD PMID:28965971 NCBI chr 1:215,541,570...215,553,446
Ensembl chr 1:215,541,542...215,553,451
JBrowse link
G Cuta cutA divalent cation tolerance homolog decreases expression ISO Zearalenone results in decreased expression of CUTA mRNA CTD PMID:19371625 NCBI chr20:5,532,024...5,533,640
Ensembl chr20:5,532,024...5,533,620
JBrowse link
G Cux1 cut-like homeobox 1 decreases expression ISO Zearalenone results in decreased expression of CUX1 mRNA CTD PMID:19371625 NCBI chr12:23,150,886...23,470,095
Ensembl chr12:23,151,180...23,445,074
JBrowse link
G Cuzd1 CUB and zona pellucida-like domains 1 increases expression EXP Zearalenone results in increased expression of CUZD1 mRNA CTD PMID:17557909 NCBI chr 1:201,881,846...201,894,970
Ensembl chr 1:201,881,836...201,894,775
JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 increases expression ISO Zearalenone results in increased expression of CXCL12 mRNA CTD PMID:27757495 PMID:28396216 NCBI chr 4:149,261,044...149,273,891
Ensembl chr 4:149,261,044...149,273,891
JBrowse link
G Cxcl9 C-X-C motif chemokine ligand 9 increases expression ISO Zearalenone results in increased expression of CXCL9 mRNA CTD PMID:27757495 NCBI chr14:17,228,832...17,233,743
Ensembl chr14:17,228,856...17,234,712
JBrowse link
G Cxcr5 C-X-C motif chemokine receptor 5 increases expression ISO Zearalenone results in increased expression of CXCR5 mRNA CTD PMID:27757495 NCBI chr 8:48,835,688...48,852,032
Ensembl chr 8:48,836,957...48,850,671
JBrowse link
G Cycs cytochrome c, somatic affects localization
increases expression
ISO Zearalenone affects the localization of CYCS protein
Zearalenone results in increased expression of CYCS protein
CTD PMID:19541794 PMID:25058043 NCBI chr 4:80,331,226...80,333,326
Ensembl chr 4:80,331,227...80,333,326
JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 decreases expression
decreases activity
multiple interactions
ISO
EXP
Zearalenone results in decreased expression of CYP11A1 mRNA; Zearalenone results in decreased expression of CYP11A1 protein
Zearalenone results in decreased activity of CYP11A1 protein
[Colforsin co-treated with Zearalenone] results in increased expression of CYP11A1 mRNA
CTD PMID:24512812 PMID:26783879 PMID:29669061 PMID:31419471 NCBI chr 8:62,798,317...62,809,848
Ensembl chr 8:62,779,875...62,809,893
JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 decreases expression ISO Zearalenone results in decreased expression of CYP17A1 mRNA CTD PMID:24512812 NCBI chr 1:266,422,127...266,429,947
Ensembl chr 1:266,422,132...266,428,239
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 decreases activity
decreases expression
ISO Zearalenone results in decreased activity of CYP19A1 protein
Zearalenone results in decreased expression of CYP19A1 mRNA; Zearalenone results in decreased expression of CYP19A1 protein
CTD PMID:16023337 PMID:29758222 NCBI chr 8:58,744,849...58,772,408
Ensembl chr 8:58,744,849...58,772,408
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
decreases expression
decreases activity
ISO Tamoxifen inhibits the reaction [Zearalenone inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]]; Tamoxifen inhibits the reaction [Zearalenone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]]; Zearalenone inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]; Zearalenone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]
Zearalenone results in decreased expression of CYP1A1 mRNA
Zearalenone results in decreased activity of CYP1A1 protein
CTD PMID:15157572 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases hydroxylation
multiple interactions
ISO CYP1A2 protein results in increased hydroxylation of Zearalenone
[CYP1A2 protein results in increased hydroxylation of Zearalenone] which results in increased chemical synthesis of Catechols
CTD PMID:19931366 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 increases activity
multiple interactions
ISO Zearalenone results in increased activity of CYP1B1 protein
Zearalenone promotes the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1B1 protein]
CTD PMID:15157572 NCBI chr 6:2,308,179...2,316,739
Ensembl chr 6:2,307,808...2,316,722
JBrowse link
G Cyp2c7 cytochrome P450, family 2, subfamily c, polypeptide 7 increases expression EXP Zearalenone results in increased expression of CYP2C7 mRNA CTD PMID:20607812 NCBI chr 1:147,422,999...148,119,979
Ensembl chr 1:148,053,687...148,119,857
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 increases expression EXP Zearalenone results in increased expression of CYP2E1 mRNA CTD PMID:20607812 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases expression EXP Zearalenone results in increased expression of CYP3A2 mRNA CTD PMID:20607812 NCBI chr12:11,641,500...11,677,818
Ensembl chr12:11,655,402...11,733,136
JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 increases expression EXP Zearalenone results in increased expression of CYP3A23-3A1 mRNA CTD PMID:20607812 NCBI chr12:11,053,888...11,082,742
Ensembl chr12:11,655,402...11,733,136
JBrowse link
G Cyp3a62 cytochrome P450, family 3, subfamily a, polypeptide 62 increases expression
multiple interactions
ISO Zearalenone results in increased expression of CYP3A4 mRNA; Zearalenone results in increased expression of CYP3A4 protein
[deoxynivalenol co-treated with Zearalenone] affects the expression of CYP3A4 mRNA; [deoxynivalenol co-treated with Zearalenone] results in decreased expression of CYP3A4 protein; [deoxynivalenol co-treated with Zearalenone] results in increased expression of CYP3A4 mRNA; [deoxynivalenol co-treated with Zearalenone] results in increased expression of CYP3A4 protein
CTD PMID:15569515 PMID:28865950 PMID:28935499 NCBI chr12:18,679,809...18,709,397
Ensembl chr12:18,678,594...18,709,397
JBrowse link
G Cyp4f18 cytochrome P450, family 4, subfamily f, polypeptide 18 multiple interactions
decreases expression
ISO [deoxynivalenol co-treated with Zearalenone] results in decreased expression of CYP4F3 mRNA; [deoxynivalenol co-treated with Zearalenone] results in increased expression of CYP4F3 mRNA
Zearalenone results in decreased expression of CYP4F3 mRNA
CTD PMID:28865950 PMID:28935499 NCBI chr16:19,501,680...19,528,935
Ensembl chr16:19,410,810...19,528,999
JBrowse link
G Cyp51 cytochrome P450, family 51 increases expression ISO Zearalenone results in increased expression of CYP51 protein CTD PMID:25058043 NCBI chr 4:27,175,564...27,194,018
Ensembl chr 4:27,175,243...27,194,018
JBrowse link
G Dars1 aspartyl-tRNA synthetase 1 decreases expression ISO Zearalenone results in decreased expression of DARS protein CTD PMID:25058043 NCBI chr13:45,074,067...45,127,815
Ensembl chr13:45,074,072...45,127,815
JBrowse link
G Dazl deleted in azoospermia-like decreases expression ISO Zearalenone results in decreased expression of DAZL mRNA; Zearalenone results in decreased expression of DAZL protein CTD PMID:28552778 PMID:31419471 NCBI chr 9:12,633,983...12,651,017
Ensembl chr 9:12,633,990...12,650,938
JBrowse link
G Ddc dopa decarboxylase decreases expression ISO Zearalenone results in decreased expression of DDC mRNA CTD PMID:24412706 NCBI chr14:91,905,919...91,996,816
Ensembl chr14:91,905,919...91,996,774
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression
multiple interactions
ISO Zearalenone results in increased expression of DDIT3 protein
2-aminoethyl diphenylborinate inhibits the reaction [Zearalenone results in increased expression of DDIT3 protein]; 4-phenylbutylamine promotes the reaction [Zearalenone results in increased expression of DDIT3 protein]
CTD PMID:30394307 PMID:31982503 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
JBrowse link
G Ddx25 DEAD-box helicase 25 decreases expression ISO Zearalenone results in decreased expression of DDX25 mRNA CTD PMID:24412631 NCBI chr 8:36,744,686...36,760,720
Ensembl chr 8:36,744,667...36,760,742
JBrowse link
G Ddx4 DEAD-box helicase 4 decreases expression ISO Zearalenone results in decreased expression of DDX4 protein; Zearalenone results in decreased expression of VASA protein CTD PMID:28089945 PMID:31419471 NCBI chr 2:44,447,610...44,504,263
Ensembl chr 2:44,447,573...44,504,354
JBrowse link
G Dhrs3 dehydrogenase/reductase 3 increases expression ISO Zearalenone results in increased expression of DHRS3 mRNA CTD PMID:19371625 NCBI chr 5:162,809,090...162,843,385
Ensembl chr 5:162,808,646...162,843,383
JBrowse link
G Dio3os DIO3 opposite strand upstream RNA decreases expression ISO Zearalenone results in decreased expression of DIO3OS mRNA CTD PMID:30790392 NCBI chr 6:134,623,450...134,626,974 JBrowse link
G Dkk2 dickkopf WNT signaling pathway inhibitor 2 decreases expression ISO Zearalenone results in decreased expression of DKK2 mRNA CTD PMID:27862621 NCBI chr 2:237,148,918...237,240,883
Ensembl chr 2:237,148,941...237,241,350
JBrowse link
G Dld dihydrolipoamide dehydrogenase increases expression ISO Zearalenone results in increased expression of DLD protein CTD PMID:25058043 NCBI chr 6:50,597,677...50,618,694
Ensembl chr 6:50,597,677...50,618,694
JBrowse link
G Dmbt1 deleted in malignant brain tumors 1 increases expression EXP Zearalenone results in increased expression of DMBT1 mRNA CTD PMID:17557909 NCBI chr 1:201,620,642...201,689,905
NCBI chr 1:203,149,414...203,228,705
JBrowse link
G Dnm1l dynamin 1-like multiple interactions ISO [Zearalenone co-treated with CGA protein] results in increased expression of DNM1L protein CTD PMID:25058043 NCBI chr11:88,830,968...88,882,271
Ensembl chr11:88,830,957...88,880,198
JBrowse link
G Dnmt1 DNA methyltransferase 1 increases expression ISO Zearalenone results in increased expression of DNMT1 mRNA CTD PMID:32119988 NCBI chr 8:21,922,515...21,968,495
Ensembl chr 8:21,922,515...21,968,495
JBrowse link
G Dok4 docking protein 4 increases expression ISO Zearalenone results in increased expression of DOK4 mRNA CTD PMID:19371625 NCBI chr19:10,563,423...10,574,094
Ensembl chr19:10,563,423...10,574,093
JBrowse link
G Dpysl2 dihydropyrimidinase-like 2 decreases expression ISO Zearalenone results in decreased expression of DPYSL2 protein CTD PMID:25058043 NCBI chr15:43,475,640...43,581,725
Ensembl chr15:43,477,629...43,542,939
JBrowse link
G Ech1 enoyl-CoA hydratase 1 decreases expression ISO Zearalenone results in decreased expression of ECH1 mRNA CTD PMID:19371625 NCBI chr 1:87,009,798...87,015,996
Ensembl chr 1:87,009,730...87,016,005
JBrowse link
G Ehmt2 euchromatic histone lysine methyltransferase 2 increases expression ISO Zearalenone results in increased expression of EHMT2 mRNA CTD PMID:32119988 NCBI chr20:4,576,033...4,592,980
Ensembl chr20:4,576,057...4,592,980
JBrowse link
G Epas1 endothelial PAS domain protein 1 increases expression ISO Zearalenone results in increased expression of EPAS1 mRNA CTD PMID:30138655 NCBI chr 6:10,306,508...10,385,239
Ensembl chr 6:10,306,405...10,387,265
JBrowse link
G Epb41l2 erythrocyte membrane protein band 4.1-like 2 increases expression ISO Zearalenone results in increased expression of EPB41L2 mRNA CTD PMID:19371625 NCBI chr 1:20,881,820...21,067,713
Ensembl chr 1:20,893,995...20,962,526
JBrowse link
G Epn3 epsin 3 decreases expression ISO Zearalenone results in decreased expression of EPN3 mRNA CTD PMID:19371625 NCBI chr10:82,220,762...82,231,200
Ensembl chr10:82,220,762...82,229,140
JBrowse link
G Erbb3 erb-b2 receptor tyrosine kinase 3 decreases expression ISO Zearalenone results in decreased expression of ERBB3 mRNA CTD PMID:19371625 NCBI chr 7:2,989,202...3,010,610
Ensembl chr 7:2,989,340...3,010,350
JBrowse link
G Ercc3 ERCC excision repair 3, TFIIH core complex helicase subunit increases expression ISO Zearalenone results in increased expression of ERCC3 mRNA CTD PMID:19371625 NCBI chr18:25,037,668...25,068,380
Ensembl chr18:25,037,625...25,068,389
JBrowse link
G Erp27 endoplasmic reticulum protein 27 decreases expression ISO Zearalenone results in decreased expression of ERP27 mRNA CTD PMID:19371625 NCBI chr 4:170,893,946...170,912,629
Ensembl chr 4:170,893,946...170,912,629
JBrowse link
G Esco1 establishment of sister chromatid cohesion N-acetyltransferase 1 increases expression ISO Zearalenone results in increased expression of ESCO1 mRNA CTD PMID:32119988 NCBI chr18:1,789,796...1,857,271
Ensembl chr18:1,789,900...1,828,606
JBrowse link
G Espn espin increases expression ISO Zearalenone results in increased expression of ESPN mRNA CTD PMID:19371625 NCBI chr 5:169,293,356...169,331,338
Ensembl chr 5:169,293,904...169,331,163
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions
decreases expression
increases activity
affects binding
affects expression
ISO
EXP
[Zearalenone binds to ESR1 protein] which results in increased activity of ALPL protein; fulvestrant inhibits the reaction [[Zearalenone binds to ESR1 protein] which results in increased activity of ALPL protein]; Zearalenone analog promotes the reaction [ESR1 protein binds to and results in increased activity of NCOA2 protein]; Zearalenone binds to and results in decreased activity of ESR1 protein; Zearalenone binds to and results in increased activity of ESR1 protein; Zearalenone promotes the reaction [ESR1 protein alternative form binds to ESR1 protein alternative form]; Zearalenone promotes the reaction [ESR1 protein binds to and results in increased activity of NCOA2 protein]; Zearalenone promotes the reaction [NCOA2 protein binds to ESR1 protein]
Zearalenone results in decreased expression of ESR1 mRNA
Zearalenone results in decreased expression of ESR1 mRNA; Zearalenone results in decreased expression of ESR1 protein
Zearalenone metabolite results in increased activity of ESR1 protein; Zearalenone results in increased activity of ESR1 protein
Zearalenone analog binds to ESR1 protein; Zearalenone binds to ESR1 protein
Zearalenone affects the expression of ESR1 mRNA; Zearalenone affects the expression of ESR1 protein
CTD PMID:9751507 PMID:11162928 PMID:11331656 PMID:11750080 PMID:12598185 PMID:12650720 PMID:15084758 PMID:15169976 PMID:19233257 PMID:19913605 PMID:20209442 PMID:22494775 PMID:22521637 PMID:25455890 PMID:27862621 PMID:28396216 PMID:28807876 PMID:28965971 PMID:29627501 PMID:30270565 PMID:31419471 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Esr2 estrogen receptor 2 multiple interactions
increases expression
decreases expression
affects binding
ISO
EXP
Zearalenone analog promotes the reaction [ESR2 protein binds to and results in increased activity of NCOA2 protein]; Zearalenone binds to and results in decreased activity of ESR2 protein; Zearalenone binds to and results in increased activity of ESR2 protein; Zearalenone promotes the reaction [ESR2 protein binds to and results in increased activity of NCOA2 protein]
Dextran Sulfate promotes the reaction [Zearalenone results in increased expression of ESR2 mRNA]
[bisphenol A co-treated with Zearalenone co-treated with Arsenic co-treated with enzacamene co-treated with Estradiol co-treated with Triiodothyronine] results in decreased expression of ESR2 mRNA; [bisphenol A co-treated with Zearalenone co-treated with Arsenic co-treated with enzacamene] results in increased expression of ESR2 mRNA; [Estradiol co-treated with Triiodothyronine] promotes the reaction [Zearalenone results in decreased expression of ESR2 mRNA]; [Zearalenone co-treated with Estradiol co-treated with Triiodothyronine] results in decreased expression of ESR2 mRNA; [Zearalenone results in increased susceptibility to [Estradiol co-treated with Triiodothyronine]] which results in decreased expression of ESR2 mRNA
Zearalenone analog binds to ESR2 protein; Zearalenone binds to ESR2 protein
CTD PMID:9751507 PMID:15084758 PMID:15169976 PMID:19913605 PMID:27338438 PMID:28807876 PMID:30270565 NCBI chr 6:99,163,953...99,214,711
Ensembl chr 6:99,164,357...99,214,251
JBrowse link
G Etfb electron transfer flavoprotein subunit beta increases expression ISO Zearalenone results in increased expression of ETFB protein CTD PMID:25058043 NCBI chr 1:98,472,776...98,486,940
Ensembl chr 1:98,472,745...98,486,976
JBrowse link
G Etfdh electron transfer flavoprotein dehydrogenase increases expression ISO Zearalenone results in increased expression of ETFDH protein CTD PMID:25058043 NCBI chr 2:178,367,547...178,389,641
Ensembl chr 2:178,367,549...178,389,608
JBrowse link
G Etnk2 ethanolamine kinase 2 increases expression ISO Zearalenone results in increased expression of ETNK2 mRNA CTD PMID:19371625 NCBI chr13:50,481,178...50,498,991
Ensembl chr13:50,481,163...50,499,140
JBrowse link
G Fabp1 fatty acid binding protein 1 increases expression ISO Zearalenone results in increased expression of FABP1 mRNA CTD PMID:32119988 NCBI chr 4:99,063,181...99,066,957
Ensembl chr 4:99,063,181...99,066,954
JBrowse link
G Fam107a family with sequence similarity 107, member A decreases expression ISO Zearalenone results in decreased expression of FAM107A mRNA CTD PMID:19371625 NCBI chr15:18,399,145...18,415,959
Ensembl chr15:18,399,515...18,415,965
JBrowse link
G Fas Fas cell surface death receptor increases expression EXP Zearalenone results in increased expression of FAS mRNA; Zearalenone results in increased expression of FAS protein CTD PMID:30600648 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G Faslg Fas ligand increases expression EXP Zearalenone results in increased expression of FASLG mRNA; Zearalenone results in increased expression of FASLG protein CTD PMID:30600648 NCBI chr13:79,696,811...79,717,581
Ensembl chr13:79,698,445...79,705,705
JBrowse link
G Fdx1 ferredoxin 1 decreases expression ISO Zearalenone results in decreased expression of FDX1 mRNA; Zearalenone results in decreased expression of FDX1 protein CTD PMID:29758222 NCBI chr 8:56,373,729...56,393,199
Ensembl chr 8:56,373,723...56,393,233
JBrowse link
G Figla folliculogenesis specific bHLH transcription factor decreases expression ISO Zearalenone results in decreased expression of FIGLA mRNA CTD PMID:28089945 NCBI chr 4:117,679,256...117,683,618
Ensembl chr 4:117,679,342...117,683,411
JBrowse link
G Fkbp4 FKBP prolyl isomerase 4 decreases expression ISO Zearalenone results in decreased expression of FKBP4 protein CTD PMID:25058043 NCBI chr 4:161,748,993...161,757,447
Ensembl chr 4:161,748,993...161,757,447
JBrowse link
G Fkbp5 FKBP prolyl isomerase 5 decreases expression ISO Zearalenone results in decreased expression of FKBP5 mRNA CTD PMID:24412631 NCBI chr20:7,976,704...8,097,290
Ensembl chr20:7,976,713...8,019,020
JBrowse link
G Fndc5 fibronectin type III domain containing 5 decreases expression ISO Zearalenone results in decreased expression of FNDC5 mRNA CTD PMID:19371625 NCBI chr 5:147,323,240...147,330,266
Ensembl chr 5:147,323,240...147,330,266
JBrowse link
G Folr1 folate receptor alpha decreases expression ISO Zearalenone results in decreased expression of FOLR1 mRNA CTD PMID:19371625 NCBI chr 1:166,934,457...166,945,864
Ensembl chr 1:166,934,460...166,943,592
JBrowse link
G Foxd1 forkhead box D1 increases expression ISO Zearalenone results in increased expression of FOXD1 mRNA CTD PMID:19371625 NCBI chr 2:28,460,068...28,462,488
Ensembl chr 2:28,460,068...28,462,488
JBrowse link
G Foxj1 forkhead box J1 decreases expression ISO Zearalenone results in decreased expression of FOXJ1 mRNA CTD PMID:19371625 NCBI chr10:105,282,090...105,289,396 JBrowse link
G Foxo1 forkhead box O1 decreases expression ISO Zearalenone results in decreased expression of FOXO1 mRNA CTD PMID:30717214 NCBI chr 2:141,451,234...141,527,016
Ensembl chr 2:141,451,234...141,527,016
JBrowse link
G Foxo3 forkhead box O3 decreases expression ISO Zearalenone results in decreased expression of FOXO3 mRNA CTD PMID:30717214 NCBI chr20:46,428,078...46,519,156
Ensembl chr20:46,428,124...46,519,144
JBrowse link
G Fshr follicle stimulating hormone receptor decreases expression EXP Zearalenone results in decreased expression of FSHR mRNA; Zearalenone results in decreased expression of FSHR protein CTD PMID:29669061 NCBI chr 6:12,796,383...12,997,817
Ensembl chr 6:12,796,383...12,997,817
JBrowse link
G G0s2 G0/G1switch 2 increases expression ISO Zearalenone results in increased expression of G0S2 mRNA CTD PMID:19371625 NCBI chr13:112,004,140...112,005,052
Ensembl chr13:112,004,140...112,005,052
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression ISO Zearalenone results in increased expression of GADD45A mRNA CTD PMID:27862621 NCBI chr 4:97,782,512...97,784,814
Ensembl chr 4:97,782,512...97,784,842
JBrowse link
G Galnt4 polypeptide N-acetylgalactosaminyltransferase 4 increases expression ISO Zearalenone results in increased expression of GALNT4 mRNA CTD PMID:19371625 NCBI chr 7:41,305,437...41,309,621 JBrowse link
G Galr2 galanin receptor 2 decreases expression ISO Zearalenone results in decreased expression of GALR2 mRNA CTD PMID:19371625 NCBI chr10:105,156,793...105,159,221
Ensembl chr10:105,156,632...105,237,611
JBrowse link
G Gap43 growth associated protein 43 decreases expression EXP Zearalenone results in decreased expression of GAP43 mRNA CTD PMID:17557909 NCBI chr11:58,624,198...58,717,916
Ensembl chr11:58,624,198...58,717,914
JBrowse link
G Gdf10 growth differentiation factor 10 decreases expression EXP Zearalenone results in decreased expression of GDF10 mRNA CTD PMID:17557909 NCBI chr16:10,250,508...10,262,383
Ensembl chr16:10,250,404...10,263,150
JBrowse link
G Gdnf glial cell derived neurotrophic factor decreases expression ISO Zearalenone results in decreased expression of GDNF protein CTD PMID:31419471 NCBI chr 2:56,884,181...56,912,964
Ensembl chr 2:56,887,987...56,910,238
JBrowse link
G Gdpd5 glycerophosphodiester phosphodiesterase domain containing 5 increases expression ISO Zearalenone results in increased expression of GDPD5 mRNA CTD PMID:19371625 NCBI chr 1:164,337,176...164,418,056
Ensembl chr 1:164,380,577...164,418,593
JBrowse link
G Gfra2 GDNF family receptor alpha 2 decreases expression EXP Zearalenone results in decreased expression of GFRA2 mRNA CTD PMID:17557909 NCBI chr15:52,557,004...52,648,984
Ensembl chr15:52,557,607...52,648,972
JBrowse link
G Gins3 GINS complex subunit 3 decreases expression ISO Zearalenone results in decreased expression of GINS3 mRNA CTD PMID:19371625 NCBI chr19:9,835,113...9,843,649
Ensembl chr19:9,835,057...9,843,673
JBrowse link
G Gjb2 gap junction protein, beta 2 increases expression EXP Zearalenone results in increased expression of GJB2 mRNA CTD PMID:17557909 NCBI chr15:37,377,313...37,394,494
Ensembl chr15:37,377,316...37,383,277
JBrowse link
G Glrx2 glutaredoxin 2 increases expression ISO Zearalenone results in increased expression of GLRX2 mRNA CTD PMID:19371625 NCBI chr13:60,529,057...60,552,115
Ensembl chr13:60,529,932...60,537,916
JBrowse link
G Gnrh1 gonadotropin releasing hormone 1 decreases expression EXP Zearalenone results in decreased expression of GNRH1 mRNA CTD PMID:29627501 NCBI chr15:44,441,856...44,446,064
Ensembl chr15:44,442,555...44,442,875
Ensembl chr15:44,442,555...44,442,875
JBrowse link
G Gnrhr gonadotropin releasing hormone receptor decreases expression EXP Zearalenone results in decreased expression of GNRHR protein CTD PMID:29627501 NCBI chr14:23,480,462...23,498,450
Ensembl chr14:23,480,462...23,498,450
JBrowse link
G Got2 glutamic-oxaloacetic transaminase 2 increases expression ISO Zearalenone results in increased expression of GOT2 protein CTD PMID:25058043 NCBI chr19:9,587,637...9,613,323
Ensembl chr19:9,587,653...9,613,340
JBrowse link
G Gper1 G protein-coupled estrogen receptor 1 affects binding
decreases expression
ISO Zearalenone binds to GPER1 protein
Zearalenone results in decreased expression of GPER1 mRNA
CTD PMID:17088055 PMID:28965971 NCBI chr12:17,309,122...17,315,267
Ensembl chr12:17,309,834...17,311,112
JBrowse link
G Gpr142 G protein-coupled receptor 142 increases expression ISO Zearalenone results in increased expression of GPR142 mRNA CTD PMID:19371625 NCBI chr10:103,341,391...103,351,710
Ensembl chr10:103,349,172...103,351,710
JBrowse link
G Gpt glutamic--pyruvic transaminase decreases expression
increases expression
increases activity
multiple interactions
ISO Zearalenone results in decreased expression of GPT protein
Zearalenone results in increased expression of GPT protein
Zearalenone results in increased activity of GPT protein
Plant Extracts inhibits the reaction [Zearalenone results in increased expression of GPT protein]; Zearalenone inhibits the reaction [Aflatoxin B1 results in increased activity of GPT protein]
CTD PMID:17385802 PMID:25058043 PMID:25445755 NCBI chr 7:117,759,083...117,761,932
Ensembl chr 7:117,759,083...117,761,931
JBrowse link
G Grb7 growth factor receptor bound protein 7 decreases expression ISO Zearalenone results in decreased expression of GRB7 mRNA CTD PMID:28965971 NCBI chr10:86,393,186...86,408,893
Ensembl chr10:86,399,827...86,409,348
JBrowse link
G Greb1 growth regulating estrogen receptor binding 1 increases expression ISO Zearalenone results in increased expression of GREB1 mRNA CTD PMID:19371625 PMID:22494775 PMID:28807876 NCBI chr 6:41,932,941...42,002,770
Ensembl chr 6:41,932,244...42,002,819
JBrowse link
G Gsdmd gasdermin D decreases expression ISO Zearalenone results in decreased expression of GSDMD mRNA CTD PMID:19371625 NCBI chr 7:116,889,147...116,894,134
Ensembl chr 7:116,889,572...116,894,134
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions
decreases activity
ISO lycopene inhibits the reaction [Zearalenone results in decreased activity of GSR protein] CTD PMID:25682699 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G H2ax H2A.X variant histone increases expression ISO Zearalenone results in increased expression of H2AX protein modified form CTD PMID:28089945 PMID:28552778 NCBI chr 8:48,665,652...48,666,981
Ensembl chr 8:48,665,652...48,666,981
JBrowse link
G Hapln3 hyaluronan and proteoglycan link protein 3 decreases expression ISO Zearalenone results in decreased expression of HAPLN3 mRNA CTD PMID:19371625 NCBI chr 1:140,827,279...140,845,386
Ensembl chr 1:140,827,295...140,835,151
JBrowse link
G Hat1 histone acetyltransferase 1 increases expression ISO Zearalenone results in increased expression of HAT1 mRNA CTD PMID:32119988 NCBI chr 3:58,022,395...58,070,067
Ensembl chr 3:58,022,238...58,070,068
JBrowse link
G Hba-a1 hemoglobin alpha, adult chain 1 decreases expression EXP Zearalenone results in decreased expression of HBA-A1 mRNA CTD PMID:17557909 NCBI chr10:15,602,794...15,603,649
Ensembl chr10:15,602,794...15,603,649
JBrowse link
G Hbb hemoglobin subunit beta decreases expression EXP Zearalenone results in decreased expression of HBB mRNA CTD PMID:17557909 NCBI chr 1:168,971,269...168,972,680
Ensembl chr 1:168,971,274...168,972,725
JBrowse link
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 increases expression
multiple interactions
ISO Zearalenone results in increased expression of HERPUD1 protein
4-phenylbutylamine promotes the reaction [Zearalenone results in increased expression of HERPUD1 protein]; HERPUD1 protein inhibits the reaction [Zearalenone results in decreased phosphorylation of RPS6KB1 protein]; HERPUD1 protein promotes the reaction [Zearalenone results in decreased phosphorylation of MAPK1 protein]; HERPUD1 protein promotes the reaction [Zearalenone results in decreased phosphorylation of MAPK3 protein]; HERPUD1 protein promotes the reaction [Zearalenone results in increased expression of CASP3 protein modified form]
CTD PMID:30394307 NCBI chr19:11,046,905...11,057,440
Ensembl chr19:11,046,909...11,057,254
JBrowse link
G Hes2 hes family bHLH transcription factor 2 increases expression ISO Zearalenone results in increased expression of HES2 mRNA CTD PMID:19371625 NCBI chr 5:169,338,097...169,339,142
Ensembl chr 5:169,338,097...169,339,142
JBrowse link
G Hist1h2bd histone cluster 1 H2B family member D decreases expression ISO Zearalenone results in decreased expression of H2BC5 mRNA CTD PMID:19371625 NCBI chr17:44,833,924...44,834,305
Ensembl chr17:44,833,924...44,834,305
JBrowse link
G Hivep1 HIVEP zinc finger 1 increases expression ISO Zearalenone results in increased expression of HIVEP1 mRNA CTD PMID:19371625 NCBI chr17:22,278,103...22,403,362
Ensembl chr17:22,278,798...22,311,392
JBrowse link
G Hk2 hexokinase 2 increases expression ISO Zearalenone results in increased expression of HK2 mRNA CTD PMID:32119988 NCBI chr 4:113,559,396...113,609,897
Ensembl chr 4:113,559,427...113,610,243
JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 decreases expression ISO Zearalenone results in decreased expression of HMGCS1 mRNA CTD PMID:25424538 NCBI chr 2:52,427,351...52,445,082
Ensembl chr 2:52,431,601...52,445,055
JBrowse link
G Hmgn2 high mobility group nucleosomal binding domain 2 decreases expression ISO Zearalenone results in decreased expression of HMGN2 mRNA CTD PMID:19371625 NCBI chr 5:152,195,359...152,198,813
Ensembl chr 5:152,195,361...152,198,813
JBrowse link
G Hnf4a hepatocyte nuclear factor 4, alpha multiple interactions ISO [deoxynivalenol co-treated with Zearalenone] affects the expression of HNF4A mRNA CTD PMID:28865950 NCBI chr 3:159,902,441...159,965,003
Ensembl chr 3:159,902,441...159,965,003
JBrowse link
G Hoxa10 homeobox A10 decreases expression ISO Zearalenone results in decreased expression of HOXA10 mRNA CTD PMID:27862621 NCBI chr 4:82,285,940...82,295,892
Ensembl chr 4:82,285,528...82,295,470
JBrowse link
G Hras HRas proto-oncogene, GTPase decreases expression ISO Zearalenone results in decreased expression of HRAS mRNA CTD PMID:30717214 NCBI chr 1:214,178,404...214,181,841
Ensembl chr 1:214,178,407...214,181,686
JBrowse link
G Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 decreases expression EXP Zearalenone results in decreased expression of HSD11B1 mRNA; Zearalenone results in decreased expression of HSD11B1 protein CTD PMID:29669061 NCBI chr13:111,946,626...111,996,536
Ensembl chr13:111,926,442...111,972,603
JBrowse link
G Hsd17b1 hydroxysteroid (17-beta) dehydrogenase 1 decreases expression ISO Zearalenone results in decreased expression of HSD17B1 protein CTD PMID:31419471 NCBI chr10:88,987,558...88,989,758
Ensembl chr10:88,987,558...88,989,757
JBrowse link
G Hsd17b11 hydroxysteroid (17-beta) dehydrogenase 11 multiple interactions ISO [Zearalenone co-treated with CGA protein] results in decreased expression of HSD17B11 protein CTD PMID:25058043 NCBI chr14:7,054,724...7,104,567
Ensembl chr14:7,073,445...7,104,566
JBrowse link
G Hsd17b14 hydroxysteroid (17-beta) dehydrogenase 14 decreases expression ISO Zearalenone results in decreased expression of HSD17B14 mRNA CTD PMID:19371625 NCBI chr 1:101,541,266...101,551,059
Ensembl chr 1:101,541,266...101,551,059
JBrowse link
G Hsd17b2 hydroxysteroid (17-beta) dehydrogenase 2 increases expression EXP Zearalenone results in increased expression of HSD17B2 mRNA CTD PMID:20607812 NCBI chr19:50,246,404...50,317,892
Ensembl chr19:50,246,402...50,317,891
JBrowse link
G Hsd17b3 hydroxysteroid (17-beta) dehydrogenase 3 decreases expression
decreases activity
ISO
EXP
Zearalenone results in decreased expression of HSD17B3 mRNA
Zearalenone results in decreased expression of HSD17B3 mRNA; Zearalenone results in decreased expression of HSD17B3 protein
Zearalenone results in decreased activity of HSD17B3 protein
CTD PMID:24512812 PMID:29669061 NCBI chr17:1,579,319...1,610,745
Ensembl chr17:1,579,319...1,610,745
JBrowse link
G Hsd17b4 hydroxysteroid (17-beta) dehydrogenase 4 decreases expression ISO Zearalenone results in decreased expression of HSD17B4 protein CTD PMID:31419471 NCBI chr18:44,810,462...44,897,677
Ensembl chr18:44,810,388...44,897,640
JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 decreases expression
decreases activity
ISO
EXP
Zearalenone results in decreased expression of HSD3B1 mRNA
Zearalenone results in decreased activity of HSD3B1 protein
CTD PMID:24512812 PMID:29669061
G Hsd3b2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 affects expression EXP Zearalenone affects the expression of HSD3B2 mRNA CTD PMID:29627501 NCBI chr 2:200,712,895...200,722,429
Ensembl chr 2:202,341,422...202,350,929
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A increases expression ISO Zearalenone results in increased expression of HSPA1A mRNA; Zearalenone results in increased expression of HSPA1A protein CTD PMID:19051279 NCBI chr20:4,875,834...4,881,751
Ensembl chr20:4,877,324...4,879,779
JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B increases expression ISO Zearalenone results in increased expression of HSPA1B mRNA CTD PMID:25424538 PMID:27862621 NCBI chr20:4,877,638...4,880,112
Ensembl chr20:2,699,712...2,701,815
JBrowse link
G Hspa4 heat shock protein family A (Hsp70) member 4 decreases expression ISO Zearalenone results in decreased expression of HSPA4 protein CTD PMID:25058043 NCBI chr10:38,601,624...38,642,397
Ensembl chr10:38,601,624...38,642,397
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 multiple interactions
increases expression
ISO 2-aminoethyl diphenylborinate inhibits the reaction [Zearalenone results in increased expression of HSPA5 protein]; 4-phenylbutylamine promotes the reaction [Zearalenone results in increased expression of HSPA5 protein] CTD PMID:30394307 PMID:31982503 NCBI chr 3:13,838,304...13,842,763
Ensembl chr 3:13,838,304...13,842,762
JBrowse link
G Hspb1 heat shock protein family B (small) member 1 increases expression ISO Zearalenone results in increased expression of HSPB1 protein CTD PMID:19051279 NCBI chr12:23,839,390...23,841,051
Ensembl chr12:23,839,399...23,841,049
JBrowse link
G Id1 inhibitor of DNA binding 1, HLH protein decreases expression ISO Zearalenone results in decreased expression of ID1 mRNA CTD PMID:25424538 NCBI chr 3:148,214,623...148,216,715
Ensembl chr 3:148,215,540...148,216,718
JBrowse link
G Id2 inhibitor of DNA binding 2 increases expression
multiple interactions
ISO Zearalenone results in increased expression of ID2 mRNA
[Tamoxifen co-treated with Zearalenone] results in increased expression of ID2 mRNA
CTD PMID:30138655 NCBI chr 6:44,360,077...44,361,908
Ensembl chr 6:44,348,501...44,363,915
JBrowse link
G Idh3a isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha increases expression ISO Zearalenone results in increased expression of IDH3A protein CTD PMID:25058043 NCBI chr 8:59,164,601...59,183,899
Ensembl chr 8:59,164,572...59,183,908
JBrowse link
G Ifitm3 interferon induced transmembrane protein 3 decreases expression ISO Zearalenone results in decreased expression of IFITM3 mRNA CTD PMID:19371625 NCBI chr 1:213,810,712...213,811,821
Ensembl chr 1:213,810,696...213,811,901
JBrowse link
G Igf1 insulin-like growth factor 1 increases expression
decreases expression
ISO Zearalenone results in increased expression of IGF1 mRNA
Zearalenone results in decreased expression of IGF1 mRNA
CTD PMID:27757495 PMID:28965971 NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609
JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 decreases expression ISO Zearalenone results in decreased expression of IGFBP3 mRNA CTD PMID:28965971 NCBI chr14:87,457,647...87,465,374
Ensembl chr14:87,457,647...87,465,374
JBrowse link
G Igfbp6 insulin-like growth factor binding protein 6 decreases expression ISO Zearalenone results in decreased expression of IGFBP6 mRNA CTD PMID:19371625 NCBI chr 7:143,749,385...143,754,018
Ensembl chr 7:143,749,221...143,754,054
JBrowse link
G Il10 interleukin 10 multiple interactions
increases expression
ISO lycopene inhibits the reaction [Zearalenone results in increased expression of IL10] CTD PMID:25682699 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il13 interleukin 13 increases expression ISO Zearalenone results in increased expression of IL13 mRNA CTD PMID:27757495 NCBI chr10:38,982,909...38,985,466
Ensembl chr10:38,982,909...38,985,466
JBrowse link
G Il18 interleukin 18 increases secretion
increases expression
multiple interactions
ISO Zearalenone results in increased secretion of IL18 protein
Zearalenone results in increased expression of IL18 mRNA
[Dextran Sulfate co-treated with Zearalenone] results in increased expression of IL18 mRNA; [Dextran Sulfate co-treated with Zearalenone] results in increased secretion of IL18 protein; Dextran Sulfate inhibits the reaction [Zearalenone results in increased secretion of IL18 protein]; Zearalenone inhibits the reaction [Dextran Sulfate results in increased expression of IL18 mRNA]; Zearalenone inhibits the reaction [Dextran Sulfate results in increased secretion of IL18 protein]
CTD PMID:30270565 NCBI chr 8:55,009,666...55,016,286
Ensembl chr 8:54,993,859...55,016,299
JBrowse link
G Il1b interleukin 1 beta multiple interactions
increases expression
increases secretion
ISO
EXP
[Dextran Sulfate co-treated with Zearalenone] results in increased secretion of IL1B protein; Lipopolysaccharides promotes the reaction [Zearalenone results in increased expression of IL1B mRNA]; Lycopene inhibits the reaction [Zearalenone results in increased expression of IL1B]; Zearalenone inhibits the reaction [Dextran Sulfate results in increased secretion of IL1B protein]
3-methyladenine promotes the reaction [[Zearalenone co-treated with Lipopolysaccharides] results in increased expression of IL1B protein modified form]; [Zearalenone co-treated with Lipopolysaccharides] results in increased expression of IL1B mRNA; [Zearalenone co-treated with Lipopolysaccharides] results in increased expression of IL1B protein; [Zearalenone co-treated with Lipopolysaccharides] results in increased expression of IL1B protein modified form; MCC-950 inhibits the reaction [[Zearalenone co-treated with Lipopolysaccharides] results in increased expression of IL1B mRNA]; MCC-950 inhibits the reaction [[Zearalenone co-treated with Lipopolysaccharides] results in increased expression of IL1B protein modified form]; NLRP3 protein promotes the reaction [[Zearalenone co-treated with Lipopolysaccharides] results in increased expression of IL1B protein modified form]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Zearalenone co-treated with Lipopolysaccharides] results in increased expression of IL1B mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Zearalenone results in increased expression of IL1B protein modified form]; Sirolimus inhibits the reaction [[Zearalenone co-treated with Lipopolysaccharides] results in increased expression of IL1B protein modified form]
Zearalenone results in increased secretion of IL1B protein
CTD PMID:16687389 PMID:25682699 PMID:30270565 PMID:31586597 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il2 interleukin 2 multiple interactions
increases expression
ISO lycopene inhibits the reaction [Zearalenone results in increased expression of IL2] CTD PMID:25682699 NCBI chr 2:123,847,150...123,851,854
Ensembl chr 2:123,847,150...123,851,854
JBrowse link
G Il4 interleukin 4 increases expression ISO Zearalenone results in increased expression of IL4 mRNA CTD PMID:27757495 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Il4r interleukin 4 receptor increases expression ISO Zearalenone results in increased expression of IL4R mRNA CTD PMID:19371625 NCBI chr 1:196,942,343...196,967,221
Ensembl chr 1:196,942,364...196,967,220
JBrowse link
G Il6 interleukin 6 multiple interactions
increases expression
ISO Lipopolysaccharides promotes the reaction [Zearalenone results in increased expression of IL6 mRNA]; lycopene inhibits the reaction [Zearalenone results in increased expression of IL6]
[Lipopolysaccharides co-treated with Zearalenone] results in increased secretion of IL6 protein; [Zearalenone co-treated with Aflatoxin B1] results in decreased expression of IL6 mRNA
CTD PMID:16687389 PMID:25682699 PMID:28965971 PMID:32328699 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Immt inner membrane mitochondrial protein increases expression ISO Zearalenone results in increased expression of IMMT protein CTD PMID:25058043 NCBI chr 4:99,753,446...99,789,921
Ensembl chr 4:99,753,500...99,792,484
JBrowse link
G Impdh2 inosine monophosphate dehydrogenase 2 increases expression ISO Zearalenone results in increased expression of IMPDH2 mRNA CTD PMID:19371625 NCBI chr 8:117,346,983...117,351,619
Ensembl chr 8:117,347,029...117,351,610
JBrowse link
G Inhba inhibin subunit beta A decreases expression ISO Zearalenone results in decreased expression of INHBA mRNA CTD PMID:30138655 NCBI chr17:51,894,869...51,919,998
Ensembl chr17:51,898,217...51,912,496
JBrowse link
G Ipo13 importin 13 increases expression ISO Zearalenone results in increased expression of IPO13 mRNA CTD PMID:19371625 NCBI chr 5:136,728,744...136,749,187
Ensembl chr 5:136,728,740...136,748,980
JBrowse link
G Itpk1 inositol-tetrakisphosphate 1-kinase increases expression ISO Zearalenone results in increased expression of ITPK1 mRNA CTD PMID:19371625 NCBI chr 6:126,448,920...126,582,188
Ensembl chr 6:126,450,139...126,582,134
JBrowse link
G Jag1 jagged canonical Notch ligand 1 increases expression ISO Zearalenone results in increased expression of JAG1 mRNA CTD PMID:30138655 NCBI chr 3:130,079,361...130,114,781
Ensembl chr 3:130,079,361...130,114,770
JBrowse link
G Kat2b lysine acetyltransferase 2B increases expression ISO Zearalenone results in increased expression of KAT2B mRNA CTD PMID:32119988 NCBI chr 9:4,440,982...4,492,949 JBrowse link
G Kcnf1 potassium voltage-gated channel modifier subfamily F member 1 increases expression ISO Zearalenone results in increased expression of KCNF1 mRNA CTD PMID:19371625 NCBI chr 6:42,471,060...42,473,738
Ensembl chr 6:42,471,066...42,473,738
JBrowse link
G Kcnj5 potassium inwardly-rectifying channel, subfamily J, member 5 increases expression ISO Zearalenone results in increased expression of KCNJ5 mRNA CTD PMID:19371625 NCBI chr 8:33,435,493...33,463,410
Ensembl chr 8:33,433,905...33,463,467
JBrowse link
G Kctd20 potassium channel tetramerization domain containing 20 increases expression ISO Zearalenone results in increased expression of KCTD20 mRNA CTD PMID:19371625 NCBI chr20:6,205,897...6,222,818
Ensembl chr20:6,205,903...6,219,936
JBrowse link
G Kdm4a lysine demethylase 4A decreases expression ISO Zearalenone results in decreased expression of KDM4A mRNA CTD PMID:24412631 NCBI chr 5:136,967,650...137,014,402
Ensembl chr 5:136,967,650...137,014,430
JBrowse link
G Kitlg KIT ligand decreases expression ISO Zearalenone results in decreased expression of KITLG mRNA CTD PMID:27757495 NCBI chr 7:42,269,784...42,351,054
Ensembl chr 7:42,269,784...42,351,054
JBrowse link
G Kmt5a lysine methyltransferase 5A increases expression ISO Zearalenone results in increased expression of KMT5A mRNA CTD PMID:32119988 NCBI chr12:37,558,150...37,581,183
Ensembl chr12:37,559,770...37,574,750
JBrowse link
G Kras KRAS proto-oncogene, GTPase increases expression
decreases expression
ISO Zearalenone results in increased expression of KRAS mRNA
Zearalenone results in decreased expression of KRAS mRNA
CTD PMID:29758222 PMID:30717214 NCBI chr 4:179,482,562...179,515,483
Ensembl chr 4:179,486,105...179,515,558
JBrowse link
G Krt10 keratin 10 decreases expression ISO Zearalenone results in decreased expression of KRT10 protein CTD PMID:25058043 NCBI chr10:87,296,445...87,301,307
Ensembl chr10:87,296,451...87,300,736
JBrowse link
G Krt17 keratin 17 decreases expression ISO Zearalenone results in decreased expression of KRT17 mRNA CTD PMID:19371625 NCBI chr10:88,158,993...88,163,712
Ensembl chr10:88,118,001...88,163,723
JBrowse link
G Krt5 keratin 5 increases expression ISO Zearalenone results in increased expression of KRT5 mRNA CTD PMID:28965971 NCBI chr 7:143,320,142...143,324,536
Ensembl chr 7:143,316,920...143,453,546
JBrowse link
G Krt7 keratin 7 increases expression EXP Zearalenone results in increased expression of KRT7 mRNA CTD PMID:17557909 NCBI chr 7:143,059,731...143,075,907
Ensembl chr 7:143,059,764...143,075,907
JBrowse link
G Ldlr low density lipoprotein receptor increases expression ISO Zearalenone results in increased expression of LDLR mRNA CTD PMID:32119988 NCBI chr 8:22,750,425...22,773,305
Ensembl chr 8:22,750,336...22,774,903
JBrowse link
G Lgals1 galectin 1 decreases expression ISO Zearalenone results in decreased expression of LGALS1 mRNA CTD PMID:19371625 NCBI chr 7:120,153,184...120,156,290
Ensembl chr 7:120,153,184...120,156,289
JBrowse link
G Lhb luteinizing hormone subunit beta decreases expression EXP Zearalenone results in decreased expression of LHB protein CTD PMID:29627501 NCBI chr 1:101,409,992...101,413,725
Ensembl chr 1:101,410,019...101,413,724
JBrowse link
G Lhcgr luteinizing hormone/choriogonadotropin receptor multiple interactions ISO [Colforsin co-treated with Zearalenone] results in increased expression of LHCGR mRNA CTD PMID:26783879 NCBI chr 6:12,493,182...12,554,482
Ensembl chr 6:12,493,943...12,554,439
JBrowse link
G Lhx8 LIM homeobox 8 decreases expression ISO Zearalenone results in decreased expression of LHX8 mRNA; Zearalenone results in decreased expression of LHX8 protein CTD PMID:28089945 NCBI chr 2:260,572,205...260,598,744
Ensembl chr 2:260,574,190...260,596,777
JBrowse link
G LOC102548901 protein Bop-like increases expression ISO Zearalenone results in increased expression of RTL10 mRNA CTD PMID:19371625 NCBI chr12:6,230,524...6,231,398 JBrowse link
G Lsp1 lymphocyte-specific protein 1 decreases expression EXP Zearalenone results in decreased expression of LSP1 mRNA CTD PMID:17557909 NCBI chr 1:215,628,750...215,662,505
Ensembl chr 1:215,628,785...215,662,504
JBrowse link
G Mak16 MAK16 homolog increases expression ISO Zearalenone results in increased expression of RBM13 mRNA CTD PMID:19371625 NCBI chr16:64,729,254...64,737,807
Ensembl chr16:64,729,221...64,737,807
JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta increases expression EXP Zearalenone results in increased expression of MAP1LC3B protein CTD PMID:31586597 NCBI chr19:53,635,449...53,643,970
Ensembl chr19:53,629,779...53,646,058
JBrowse link
G Mapk1 mitogen activated protein kinase 1 decreases phosphorylation
multiple interactions
ISO Zearalenone results in decreased phosphorylation of MAPK1 protein
HERPUD1 protein promotes the reaction [Zearalenone results in decreased phosphorylation of MAPK1 protein]
CTD PMID:30394307 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk13 mitogen activated protein kinase 13 decreases expression ISO Zearalenone results in decreased expression of MAPK13 mRNA CTD PMID:19371625 NCBI chr20:6,018,374...6,027,467
Ensembl chr20:6,018,374...6,027,473
JBrowse link
G Mapk3 mitogen activated protein kinase 3 decreases phosphorylation
multiple interactions
ISO Zearalenone results in decreased phosphorylation of MAPK3 protein
HERPUD1 protein promotes the reaction [Zearalenone results in decreased phosphorylation of MAPK3 protein]
CTD PMID:30394307 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 increases phosphorylation
increases expression
ISO Zearalenone results in increased phosphorylation of MAPK8 protein
Zearalenone results in increased expression of MAPK8 mRNA
CTD PMID:21767629 PMID:30717214 NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347
JBrowse link
G Mas1 MAS1 proto-oncogene, G protein-coupled receptor increases expression ISO Zearalenone results in increased expression of MAS1 mRNA CTD PMID:24412631 NCBI chr 1:48,076,761...48,108,218
Ensembl chr 1:48,077,033...48,108,216
JBrowse link
G Mdh2 malate dehydrogenase 2 increases expression ISO Zearalenone results in increased expression of MDH2 protein CTD PMID:25058043 NCBI chr12:23,941,451...23,954,406
Ensembl chr12:23,941,448...23,954,431
JBrowse link
G Mdk midkine decreases expression ISO Zearalenone results in decreased expression of MDK mRNA CTD PMID:19371625 NCBI chr 3:80,841,003...80,843,895
Ensembl chr 3:80,841,005...80,842,916
JBrowse link
G Meox1 mesenchyme homeobox 1 decreases expression ISO Zearalenone results in decreased expression of MEOX1 mRNA CTD PMID:19371625 NCBI chr10:89,797,011...89,817,009
Ensembl chr10:89,797,038...89,816,491
JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase increases expression ISO Zearalenone results in increased expression of MET mRNA CTD PMID:19371625 NCBI chr 4:44,747,467...44,854,628
Ensembl chr 4:44,774,741...44,852,665
JBrowse link
G Mfge8 milk fat globule EGF and factor V/VIII domain containing decreases expression ISO Zearalenone results in decreased expression of MFGE8 mRNA CTD PMID:19371625 NCBI chr 1:140,845,478...140,860,882
Ensembl chr 1:140,845,465...140,860,894
JBrowse link
G Mfn2 mitofusin 2 increases expression ISO Zearalenone results in increased expression of MFN2 mRNA CTD PMID:19371625 NCBI chr 5:164,684,244...164,715,414
Ensembl chr 5:164,684,509...164,714,145
JBrowse link
G Mgll monoglyceride lipase multiple interactions ISO [Zearalenone co-treated with CGA protein] results in decreased expression of MGLL protein CTD PMID:25058043 NCBI chr 4:120,671,436...120,773,458
Ensembl chr 4:120,671,489...120,771,088
JBrowse link
G Mill1 MHC I like leukocyte 1 increases expression ISO Zearalenone results in increased expression of MICA mRNA CTD PMID:27757495 NCBI chr 1:79,631,266...79,657,943
Ensembl chr 1:79,631,668...79,657,941
JBrowse link
G Mir146b microRNA 146b decreases expression ISO Zearalenone results in decreased expression of MIR146B mRNA CTD PMID:30717214 NCBI chr 1:266,089,488...266,089,575
Ensembl chr 1:266,089,488...266,089,575
JBrowse link
G Mir185 microRNA 185 decreases expression ISO Zearalenone results in decreased expression of MIR185 mRNA CTD PMID:30717214 NCBI chr11:86,812,702...86,812,781
Ensembl chr11:86,812,702...86,812,781
JBrowse link
G Mir19a microRNA 19a increases expression ISO Zearalenone results in increased expression of MIR19A mRNA CTD PMID:30717214 NCBI chr15:100,180,162...100,180,243
Ensembl chr15:100,180,162...100,180,243
JBrowse link
G Mir210 microRNA 210 decreases expression ISO Zearalenone results in decreased expression of MIR210 mRNA CTD PMID:30717214 NCBI chr 1:214,208,355...214,208,464 JBrowse link
G Mir221 microRNA 221 increases expression ISO Zearalenone results in increased expression of MIR221 mRNA CTD PMID:30717214 NCBI chr  X:3,684,480...3,684,588
Ensembl chr  X:3,684,480...3,684,588
JBrowse link
G Mir301a microRNA 301a decreases expression ISO Zearalenone results in decreased expression of MIR301 mRNA CTD PMID:30717214 NCBI chr10:74,417,746...74,417,845
Ensembl chr10:74,417,746...74,417,845
JBrowse link
G Mir326 microRNA 326 decreases expression ISO Zearalenone results in decreased expression of MIR326 mRNA CTD PMID:30717214 NCBI chr 1:164,518,401...164,518,495
Ensembl chr 1:164,518,401...164,518,495
JBrowse link
G Mir410 microRNA 410 decreases expression ISO Zearalenone results in decreased expression of MIR410 mRNA CTD PMID:30717214 NCBI chr 6:133,893,997...133,894,072
Ensembl chr 6:133,893,993...133,894,073
JBrowse link
G Mir411 microRNA 411 decreases expression ISO Zearalenone results in decreased expression of MIR411 mRNA CTD PMID:30717214 NCBI chr 6:133,858,849...133,858,924
Ensembl chr 6:133,858,844...133,858,939
JBrowse link
G Mir615 microRNA 615 decreases expression ISO Zearalenone results in decreased expression of MIR615 mRNA CTD PMID:30717214 NCBI chr 7:144,629,019...144,629,110
Ensembl chr 7:144,629,019...144,629,110
JBrowse link
G Mir96 microRNA 96 affects expression ISO Zearalenone affects the expression of MIR96 mRNA CTD PMID:30717214 NCBI chr 4:57,463,366...57,463,471
Ensembl chr 4:57,463,366...57,463,471
JBrowse link
G Mki67 marker of proliferation Ki-67 increases expression ISO Zearalenone results in increased expression of MKI67 mRNA CTD PMID:28965971 NCBI chr 1:207,993,895...208,020,454
Ensembl chr 1:207,993,895...208,020,454
JBrowse link
G Mlh1 mutL homolog 1 increases expression ISO Zearalenone results in increased expression of MLH1 mRNA; Zearalenone results in increased expression of MLH1 protein CTD PMID:28552778 NCBI chr 8:119,486,655...119,523,716
Ensembl chr 8:119,486,691...119,523,964
JBrowse link
G Mlph melanophilin increases expression ISO Zearalenone results in increased expression of MLPH mRNA CTD PMID:19371625 NCBI chr 9:98,072,965...98,108,429
Ensembl chr 9:98,073,038...98,108,433
JBrowse link
G Mmp2 matrix metallopeptidase 2 increases expression ISO Zearalenone results in increased expression of MMP2 mRNA CTD PMID:28965971 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611
JBrowse link
G Mmp7 matrix metallopeptidase 7 increases expression EXP Zearalenone results in increased expression of MMP7 mRNA CTD PMID:17557909 NCBI chr 8:5,893,253...5,900,965
Ensembl chr 8:5,893,249...5,901,049
JBrowse link
G Mpo myeloperoxidase multiple interactions
increases secretion
ISO [Dextran Sulfate co-treated with Zearalenone] results in increased secretion of MPO protein; Zearalenone inhibits the reaction [Dextran Sulfate results in increased secretion of MPO protein]
Zearalenone results in increased secretion of MPO protein
CTD PMID:30270565 NCBI chr10:75,087,892...75,098,260
Ensembl chr10:75,087,892...75,098,260
JBrowse link
G Msmb microseminoprotein, beta increases expression ISO Zearalenone results in increased expression of MSMB mRNA CTD PMID:19371625 NCBI chr16:8,280,275...8,300,853
Ensembl chr16:8,280,275...8,300,852
JBrowse link
G Mtarc2 mitochondrial amidoxime reducing component 2 increases expression ISO Zearalenone results in increased expression of MTARC2 protein CTD PMID:25058043 NCBI chr13:102,724,266...102,755,511
Ensembl chr13:102,724,348...102,756,174
JBrowse link
G Mthfd1l methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like increases expression ISO Zearalenone results in increased expression of MTHFD1L protein CTD PMID:25058043 NCBI chr 1:40,529,092...40,719,232
Ensembl chr 1:40,529,045...40,719,391
JBrowse link
G Mtor mechanistic target of rapamycin kinase decreases phosphorylation
multiple interactions
EXP
ISO
Zearalenone results in decreased phosphorylation of MTOR protein
2-aminoethyl diphenylborinate inhibits the reaction [Zearalenone results in decreased phosphorylation of MTOR protein]; acadesine promotes the reaction [Zearalenone results in decreased phosphorylation of MTOR protein]; Acetylcysteine inhibits the reaction [Zearalenone results in decreased phosphorylation of MTOR protein]; dorsomorphin inhibits the reaction [Zearalenone results in decreased phosphorylation of MTOR protein]
CTD PMID:31586597 PMID:31982503 NCBI chr 5:165,263,813...165,373,967
Ensembl chr 5:165,263,800...165,373,967
JBrowse link
G Muc2 mucin 2, oligomeric mucus/gel-forming multiple interactions ISO [Aflatoxin M1 co-treated with Zearalenone co-treated with ochratoxin A] results in decreased expression of MUC2 mRNA; [Aflatoxin M1 co-treated with Zearalenone co-treated with ochratoxin A] results in decreased secretion of MUC2 protein; [Aflatoxin M1 co-treated with Zearalenone] results in decreased expression of MUC2 mRNA; [Aflatoxin M1 co-treated with Zearalenone] results in decreased secretion of MUC2 protein CTD PMID:30904571 NCBI chr 1:214,663,929...214,693,197 JBrowse link
G Muc4 mucin 4, cell surface associated increases expression EXP Zearalenone results in increased expression of MUC4 mRNA CTD PMID:17557909 NCBI chr11:71,242,973...71,285,217
Ensembl chr11:71,243,334...71,284,939
JBrowse link
G Muc5ac mucin 5AC, oligomeric mucus/gel-forming increases expression
multiple interactions
ISO Zearalenone results in increased expression of MUC5AC mRNA
[Aflatoxin M1 co-treated with Zearalenone co-treated with ochratoxin A] results in decreased expression of MUC5AC mRNA; [Aflatoxin M1 co-treated with Zearalenone co-treated with ochratoxin A] results in increased secretion of MUC5AC protein; [Aflatoxin M1 co-treated with Zearalenone] results in decreased expression of MUC5AC mRNA; Zearalenone results in increased expression of and results in increased secretion of MUC5AC protein
CTD PMID:24496642 PMID:30904571 NCBI chr 1:214,725,482...214,756,653 JBrowse link
G Muc5b mucin 5B, oligomeric mucus/gel-forming multiple interactions
increases expression
ISO [Aflatoxin M1 co-treated with Zearalenone co-treated with ochratoxin A] results in decreased expression of MUC5B mRNA; [Aflatoxin M1 co-treated with Zearalenone co-treated with ochratoxin A] results in decreased secretion of MUC5B protein; [Aflatoxin M1 co-treated with Zearalenone] results in decreased expression of MUC5B mRNA; [Aflatoxin M1 co-treated with Zearalenone] results in decreased secretion of MUC5B protein; Zearalenone results in increased expression of and results in increased secretion of MUC5B protein
Zearalenone results in increased expression of MUC5B mRNA
CTD PMID:24496642 PMID:30904571 NCBI chr 1:214,778,459...214,811,237
Ensembl chr 1:214,778,496...214,810,720
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor increases expression ISO Zearalenone results in increased expression of MYC mRNA CTD PMID:28965971 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor increases expression ISO Zearalenone results in increased expression of MYD88 mRNA CTD PMID:27757495 NCBI chr 8:128,022,512...128,027,462
Ensembl chr 8:128,022,473...128,026,841
JBrowse link
G Nasp nuclear autoantigenic sperm protein decreases expression EXP Zearalenone results in decreased expression of NASP mRNA CTD PMID:17557909 NCBI chr 5:135,446,485...135,472,113
Ensembl chr 5:135,446,962...135,472,116
JBrowse link
G Ncmap noncompact myelin associated protein increases expression ISO Zearalenone results in increased expression of NCMAP mRNA CTD PMID:19371625 NCBI chr 5:153,729,250...153,737,161
Ensembl chr 5:153,729,250...153,737,161
JBrowse link
G Ncoa2 nuclear receptor coactivator 2 multiple interactions ISO Zearalenone analog promotes the reaction [ESR1 protein binds to and results in increased activity of NCOA2 protein]; Zearalenone analog promotes the reaction [ESR2 protein binds to and results in increased activity of NCOA2 protein]; Zearalenone promotes the reaction [ESR1 protein binds to and results in increased activity of NCOA2 protein]; Zearalenone promotes the reaction [ESR2 protein binds to and results in increased activity of NCOA2 protein]; Zearalenone promotes the reaction [NCOA2 protein binds to ESR1 protein] CTD PMID:15084758 PMID:28807876 NCBI chr 5:5,466,544...5,696,540
Ensembl chr 5:5,616,483...5,694,598
JBrowse link
G Neil2 nei-like DNA glycosylase 2 increases expression ISO Zearalenone results in increased expression of NEIL2 mRNA CTD PMID:19371625 NCBI chr15:46,371,780...46,382,730
Ensembl chr15:46,372,485...46,381,967
JBrowse link
G Nfkbia NFKB inhibitor alpha increases phosphorylation EXP Zearalenone results in increased phosphorylation of NFKBIA protein CTD PMID:31586597 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
JBrowse link
G Ngef neuronal guanine nucleotide exchange factor decreases expression ISO Zearalenone results in decreased expression of NGEF mRNA CTD PMID:19371625 NCBI chr 9:94,569,286...94,601,852
Ensembl chr 9:94,569,286...94,601,852
JBrowse link
G Niban2 niban apoptosis regulator 2 decreases expression ISO Zearalenone results in decreased expression of NIBAN2 mRNA CTD PMID:19371625 NCBI chr 3:11,921,715...11,971,327
Ensembl chr 3:11,921,715...11,971,327
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 increases expression
multiple interactions
ISO
EXP
Zearalenone results in increased expression of NLRP3 mRNA; Zearalenone results in increased expression of NLRP3 protein
NLRP3 protein promotes the reaction [[Zearalenone co-treated with Lipopolysaccharides] results in increased expression of CASP1 protein modified form]; NLRP3 protein promotes the reaction [[Zearalenone co-treated with Lipopolysaccharides] results in increased expression of IL1B protein modified form]; NLRP3 protein promotes the reaction [[Zearalenone co-treated with Lipopolysaccharides] results in increased expression of TNF protein]
[Dextran Sulfate co-treated with Zearalenone] results in increased expression of NLRP3 mRNA; [Dextran Sulfate co-treated with Zearalenone] results in increased expression of NLRP3 protein; Dextran Sulfate inhibits the reaction [Zearalenone results in increased expression of NLRP3 mRNA]; Zearalenone inhibits the reaction [Dextran Sulfate results in increased expression of NLRP3 mRNA]; Zearalenone inhibits the reaction [Dextran Sulfate results in increased expression of NLRP3 protein]
CTD PMID:30270565 PMID:31586597 NCBI chr10:45,884,324...45,918,290
Ensembl chr10:45,893,018...45,918,254
JBrowse link
G Nme1 NME/NM23 nucleoside diphosphate kinase 1 increases expression ISO Zearalenone results in increased expression of NME1 mRNA CTD PMID:28965971 NCBI chr10:81,657,152...81,666,542
Ensembl chr10:81,657,153...81,666,523
JBrowse link
G Nobox NOBOX oogenesis homeobox decreases expression ISO Zearalenone results in decreased expression of NOBOX mRNA CTD PMID:28089945 NCBI chr 4:72,749,239...72,757,066
Ensembl chr 4:72,751,382...72,756,887
JBrowse link
G Notch1 notch receptor 1 multiple interactions ISO [Zearalenone co-treated with Aflatoxin B1] results in increased expression of NOTCH1 mRNA CTD PMID:28965971 NCBI chr 3:3,905,562...3,951,015
Ensembl chr 3:3,905,453...3,951,025
JBrowse link
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 increases expression ISO Zearalenone results in increased expression of NR1H3 mRNA CTD PMID:32119988 NCBI chr 3:80,004,130...80,014,197
Ensembl chr 3:80,004,130...80,012,750
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases activity
decreases expression
ISO
EXP
Zearalenone results in increased activity of NR1I2 protein
Zearalenone results in decreased expression of NR1I2 mRNA
CTD PMID:15569515 PMID:20607812 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 increases activity ISO Zearalenone results in increased activity of NR1I3 protein CTD PMID:28927721 NCBI chr13:89,585,072...89,591,278
Ensembl chr13:89,586,283...89,591,277
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 decreases expression ISO Zearalenone results in decreased expression of NR3C1 mRNA CTD PMID:28965971 NCBI chr18:31,728,373...32,704,022
Ensembl chr18:31,728,373...31,749,647
JBrowse link
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 decreases expression
increases expression
multiple interactions
ISO Zearalenone results in decreased expression of NR4A1 protein
Zearalenone results in increased expression of NR4A1 mRNA
Colforsin promotes the reaction [Zearalenone results in increased expression of NR4A1 mRNA]
CTD PMID:24512812 PMID:26783879 NCBI chr 7:142,899,358...142,920,216
Ensembl chr 7:142,905,758...142,920,216
JBrowse link
G Nr5a1 nuclear receptor subfamily 5, group A, member 1 decreases expression EXP Zearalenone results in decreased expression of NR5A1 mRNA; Zearalenone results in decreased expression of NR5A1 protein CTD PMID:29669061 NCBI chr 3:22,998,900...23,020,441
Ensembl chr 3:22,999,616...23,020,441
JBrowse link
G Nrip1 nuclear receptor interacting protein 1 increases expression ISO Zearalenone results in increased expression of NRIP1 mRNA CTD PMID:19371625 NCBI chr11:14,658,225...14,742,478
Ensembl chr11:14,658,225...14,741,563
JBrowse link
G Nrtn neurturin increases expression ISO Zearalenone results in increased expression of NRTN mRNA CTD PMID:19371625 NCBI chr 9:10,299,881...10,306,599
Ensembl chr 9:10,305,470...10,306,597
JBrowse link
G Olfm1 olfactomedin 1 increases expression ISO Zearalenone results in increased expression of OLFM1 mRNA CTD PMID:19371625 NCBI chr 3:6,761,031...6,798,739
Ensembl chr 3:6,773,813...6,798,737
JBrowse link
G Olfml3 olfactomedin-like 3 increases expression ISO Zearalenone results in increased expression of OLFML3 mRNA CTD PMID:19371625 NCBI chr 2:206,219,419...206,222,248
Ensembl chr 2:206,219,419...206,222,248
JBrowse link
G P4hb prolyl 4-hydroxylase subunit beta multiple interactions ISO [Zearalenone co-treated with CGA protein] results in decreased expression of P4HB protein CTD PMID:25058043 NCBI chr10:109,736,459...109,748,070
Ensembl chr10:109,736,458...109,747,987
JBrowse link
G Paics phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase decreases expression ISO Zearalenone results in decreased expression of PAICS protein CTD PMID:25058043 NCBI chr14:33,563,884...33,580,944
Ensembl chr14:33,563,886...33,580,566
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage
decreases expression
EXP
ISO
Zearalenone results in increased cleavage of PARP1 protein
Zearalenone results in decreased expression of PARP1 protein
CTD PMID:24530352 PMID:28089945 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Pc pyruvate carboxylase increases expression ISO Zearalenone results in increased expression of PCX protein CTD PMID:25058043 NCBI chr 1:219,759,157...219,859,854
Ensembl chr 1:219,759,183...219,859,848
JBrowse link
G Pck2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) increases expression ISO Zearalenone results in increased expression of PCK2 protein CTD PMID:25058043 NCBI chr15:34,216,735...34,224,357
Ensembl chr15:34,216,833...34,224,193
JBrowse link
G Pclaf PCNA clamp associated factor decreases expression ISO Zearalenone results in decreased expression of PCLAF mRNA CTD PMID:19371625 NCBI chr 8:71,514,281...71,526,182
Ensembl chr 8:71,514,281...71,526,182
JBrowse link
G Pdcd1 programmed cell death 1 increases expression ISO Zearalenone results in increased expression of PDCD1 mRNA CTD PMID:27757495 NCBI chr 9:101,305,742...101,319,937
Ensembl chr 9:101,307,764...101,319,845
JBrowse link
G Pdcd6ip programmed cell death 6 interacting protein multiple interactions ISO [Zearalenone co-treated with CGA protein] results in increased expression of PDCD6IP protein CTD PMID:25058043 NCBI chr 8:121,916,233...121,973,145
Ensembl chr 8:121,916,185...121,973,125
JBrowse link
G Pdcd7 programmed cell death 7 increases expression ISO Zearalenone results in increased expression of PDCD7 mRNA CTD PMID:19371625 NCBI chr 8:70,860,671...70,875,471
Ensembl chr 8:70,860,671...70,875,471
JBrowse link
G Pdha1 pyruvate dehydrogenase E1 subunit alpha 1 increases expression ISO Zearalenone results in increased expression of PDHA1 protein CTD PMID:25058043 NCBI chr  X:37,329,779...37,343,410
Ensembl chr  X:37,329,779...37,343,410
JBrowse link
G Pfkfb2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 decreases expression ISO Zearalenone results in decreased expression of PFKFB2 mRNA CTD PMID:19371625 NCBI chr13:47,413,453...47,440,682
Ensembl chr13:47,413,458...47,440,682
JBrowse link
G Pgd phosphogluconate dehydrogenase decreases expression ISO Zearalenone results in decreased expression of PGD protein CTD PMID:25058043 NCBI chr 5:165,966,128...165,982,327 JBrowse link
G Pgk1 phosphoglycerate kinase 1 decreases expression ISO Zearalenone results in decreased expression of PGK1 protein CTD PMID:25058043 NCBI chr  X:77,263,399...77,279,373
Ensembl chr  X:77,263,359...77,279,367
JBrowse link
G Pgr progesterone receptor increases expression
multiple interactions
ISO Zearalenone results in increased expression of PGR mRNA; Zearalenone results in increased expression of PGR protein
fulvestrant inhibits the reaction [Zearalenone results in increased expression of PGR protein]; Zearalenone inhibits the reaction [Progesterone binds to and results in increased activity of PGR protein]
CTD PMID:19371625 PMID:21803136 PMID:28807876 PMID:28965971 NCBI chr 8:7,128,656...7,187,796
Ensembl chr 8:7,128,656...7,187,796
JBrowse link
G Phb prohibitin increases expression ISO Zearalenone results in increased expression of PHB protein CTD PMID:25058043 NCBI chr10:83,476,107...83,488,878
Ensembl chr10:83,476,107...83,488,878
JBrowse link
G Phb2 prohibitin 2 increases expression ISO Zearalenone results in increased expression of PHB2 protein CTD PMID:25058043 NCBI chr 4:157,230,769...157,235,375
Ensembl chr 4:157,230,769...157,235,367
JBrowse link
G Phf11 PHD finger protein 11 decreases expression ISO Zearalenone results in decreased expression of PHF11 mRNA CTD PMID:19371625 NCBI chr15:38,692,817...39,683,417
Ensembl chr15:38,647,779...38,709,984
JBrowse link
G Phgdh phosphoglycerate dehydrogenase multiple interactions ISO [Zearalenone co-treated with CGA protein] results in increased expression of PHGDH protein CTD PMID:25058043 NCBI chr 2:200,484,245...200,513,564
Ensembl chr 2:200,484,246...200,513,564
JBrowse link
G Pik3cd phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta increases expression ISO Zearalenone results in increased expression of PIK3CD mRNA CTD PMID:30138655 NCBI chr 5:166,602,053...166,628,028
Ensembl chr 5:166,602,053...166,628,028
JBrowse link
G Pim1 Pim-1 proto-oncogene, serine/threonine kinase increases expression ISO Zearalenone results in increased expression of PIM1 mRNA CTD PMID:19371625 NCBI chr20:8,165,423...8,169,557
Ensembl chr20:8,165,307...8,169,555
JBrowse link
G Piwil1 piwi-like RNA-mediated gene silencing 1 decreases expression ISO Zearalenone results in decreased expression of PIWIL1 protein CTD PMID:31419471 NCBI chr12:31,608,641...31,629,961
Ensembl chr12:31,609,053...31,629,881
JBrowse link
G Plcb1 phospholipase C beta 1 increases expression ISO Zearalenone results in increased expression of PLCB1 mRNA CTD PMID:19371625 NCBI chr 3:127,721,244...128,419,565
Ensembl chr 3:128,155,069...128,419,545
JBrowse link
G Plin1 perilipin 1 increases expression ISO Zearalenone results in increased expression of PLIN1 protein CTD PMID:25058043 NCBI chr 1:141,458,907...141,470,927
Ensembl chr 1:141,458,181...141,471,010
JBrowse link
G Plppr2 phospholipid phosphatase related 2 increases expression ISO Zearalenone results in increased expression of PLPPR2 mRNA CTD PMID:19371625 NCBI chr 8:22,946,787...22,959,554
Ensembl chr 8:22,947,152...22,959,554
JBrowse link
G Plxdc2 plexin domain containing 2 increases expression ISO Zearalenone results in increased expression of PLXDC2 mRNA CTD PMID:19371625 NCBI chr17:83,221,795...83,619,291
Ensembl chr17:83,221,827...83,610,272
JBrowse link
G Polr2c RNA polymerase II subunit C increases expression ISO Zearalenone results in increased expression of POLR2C mRNA CTD PMID:19371625 NCBI chr19:10,575,060...10,581,842
Ensembl chr19:10,575,060...10,581,842
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha increases expression ISO Zearalenone results in increased expression of PPARA mRNA CTD PMID:32119988 NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma decreases activity
decreases methylation
increases expression
ISO Zearalenone results in decreased activity of PPARG protein
Zearalenone results in decreased methylation of PPARG promoter
Zearalenone results in increased expression of PPARG mRNA; Zearalenone results in increased expression of PPARG protein
CTD PMID:27481073 PMID:32119988 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Prdm14 PR/SET domain 14 increases expression ISO Zearalenone results in increased expression of PRDM14 mRNA CTD PMID:19371625 NCBI chr 5:5,710,076...5,730,560
Ensembl chr 5:5,710,392...5,730,560
JBrowse link
G Prep prolyl endopeptidase decreases expression ISO Zearalenone results in decreased expression of PREP protein CTD PMID:25058043 NCBI chr20:50,172,618...50,269,992
Ensembl chr20:50,172,618...50,269,992
JBrowse link
G Prh1 proline rich protein HaeIII subfamily 1 decreases expression EXP Zearalenone results in decreased expression of PRH1 mRNA CTD PMID:17557909
G Prkaa2 protein kinase AMP-activated catalytic subunit alpha 2 increases expression ISO Zearalenone results in increased expression of PRKAA2 mRNA CTD PMID:30717214 NCBI chr 5:124,568,845...124,642,569
Ensembl chr 5:124,574,079...124,642,569
JBrowse link
G Prkar2a protein kinase cAMP-dependent type II regulatory subunit alpha increases expression ISO Zearalenone results in increased expression of PRKAR2A mRNA CTD PMID:19371625 NCBI chr 8:117,486,085...117,548,768
Ensembl chr 8:117,486,083...117,546,370
JBrowse link
G Prmt6 protein arginine methyltransferase 6 increases expression ISO Zearalenone results in increased expression of PRMT6 mRNA CTD PMID:32119988 NCBI chr 2:213,173,403...213,180,721
Ensembl chr 2:213,173,403...213,178,632
Ensembl chr 2:213,173,403...213,178,632
JBrowse link
G Prss23 serine protease 23 increases expression ISO Zearalenone results in increased expression of PRSS23 mRNA CTD PMID:22494775 NCBI chr 1:153,732,528...153,742,111
Ensembl chr 1:153,732,532...153,752,541
JBrowse link
G Pten phosphatase and tensin homolog increases expression ISO Zearalenone results in increased expression of PTEN mRNA CTD PMID:30717214 NCBI chr 1:251,421,814...251,487,634
Ensembl chr 1:251,421,596...251,487,832
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression ISO Zearalenone results in increased expression of PTGS2 mRNA CTD PMID:27757495 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Pycard PYD and CARD domain containing increases expression
multiple interactions
ISO
EXP
Zearalenone results in increased expression of PYCARD mRNA; Zearalenone results in increased expression of PYCARD protein
[Zearalenone co-treated with Lipopolysaccharides] results in increased expression of PYCARD protein
[Dextran Sulfate co-treated with Zearalenone] results in increased expression of PYCARD mRNA; [Dextran Sulfate co-treated with Zearalenone] results in increased expression of PYCARD protein; Zearalenone inhibits the reaction [Dextran Sulfate results in increased expression of PYCARD mRNA]; Zearalenone inhibits the reaction [Dextran Sulfate results in increased expression of PYCARD protein]
CTD PMID:30270565 PMID:31586597 NCBI chr 1:199,438,029...199,439,062
Ensembl chr 1:199,437,832...199,439,210
JBrowse link
G Rab20 RAB20, member RAS oncogene family decreases expression ISO Zearalenone results in decreased expression of RAB20 mRNA CTD PMID:19371625 NCBI chr16:83,358,116...83,382,326
Ensembl chr16:83,358,116...83,382,326
JBrowse link
G Rack1 receptor for activated C kinase 1 increases expression ISO Zearalenone results in increased expression of RACK1 mRNA; Zearalenone results in increased expression of RACK1 protein CTD PMID:32328699 NCBI chr10:34,149,717...34,155,198
Ensembl chr10:34,149,717...34,155,198
Ensembl chr12:34,149,717...34,155,198
JBrowse link
G Rad51 RAD51 recombinase decreases expression
increases expression
ISO Zearalenone results in decreased expression of RAD51 mRNA
Zearalenone results in increased expression of RAD51 mRNA; Zearalenone results in increased expression of RAD51 protein
CTD PMID:27862621 PMID:28552778 NCBI chr 3:110,918,240...110,942,920
Ensembl chr 3:110,918,243...110,942,917
JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase increases expression ISO Zearalenone results in increased expression of RAF1 mRNA CTD PMID:29758222 NCBI chr 4:147,532,040...147,592,769
Ensembl chr 4:147,532,042...147,592,699
JBrowse link
G Rap1a RAP1A, member of RAS oncogene family decreases expression ISO Zearalenone results in decreased expression of RAP1A mRNA CTD PMID:30717214 NCBI chr 2:208,193,950...208,215,186
Ensembl chr 2:208,193,954...208,215,187
JBrowse link
G Rap1b RAP1B, member of RAS oncogene family decreases expression ISO Zearalenone results in decreased expression of RAP1B mRNA CTD PMID:30717214 NCBI chr 7:60,850,406...60,878,226
Ensembl chr 7:60,853,930...60,860,990
JBrowse link
G Rarb retinoic acid receptor, beta decreases expression ISO Zearalenone results in decreased expression of RARB mRNA CTD PMID:28965971 NCBI chr15:9,915,223...10,262,599
Ensembl chr15:10,120,206...10,262,599
JBrowse link
G Rars1 arginyl-tRNA synthetase 1 decreases expression ISO Zearalenone results in decreased expression of RARS protein CTD PMID:25058043 NCBI chr10:20,633,630...20,658,074
Ensembl chr10:20,633,632...20,658,100
JBrowse link
G Rassf1 Ras association domain family member 1 increases expression ISO Zearalenone results in increased expression of RASSF1 mRNA CTD PMID:28965971 NCBI chr 8:116,307,149...116,318,289
Ensembl chr 8:116,307,141...116,318,289
JBrowse link
G Rbm24 RNA binding motif protein 24 increases expression ISO Zearalenone results in increased expression of RBM24 mRNA CTD PMID:19371625 NCBI chr17:18,671,037...18,682,876
Ensembl chr17:18,671,044...18,682,876
JBrowse link
G Rbp1 retinol binding protein 1 decreases expression ISO Zearalenone results in decreased expression of RBP1 mRNA CTD PMID:19371625 NCBI chr 8:106,449,321...106,470,842
Ensembl chr 8:106,449,321...106,470,842
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions EXP 3-methyladenine promotes the reaction [Zearalenone results in increased phosphorylation of and affects the localization of RELA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Zearalenone results in increased phosphorylation of and affects the localization of RELA protein]; Sirolimus inhibits the reaction [Zearalenone results in increased phosphorylation of and affects the localization of RELA protein]; Zearalenone results in increased phosphorylation of and affects the localization of RELA protein CTD PMID:31586597 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Ribc2 RIB43A domain with coiled-coils 2 decreases expression ISO Zearalenone results in decreased expression of RIBC2 mRNA CTD PMID:19371625 NCBI chr 7:126,028,371...126,043,371
Ensembl chr 7:126,028,350...126,043,847
JBrowse link
G Rmi2 RecQ mediated genome instability 2 decreases expression ISO Zearalenone results in decreased expression of RMI2 mRNA CTD PMID:19371625 NCBI chr10:4,904,458...4,910,339
Ensembl chr10:4,905,210...4,910,305
JBrowse link
G Rnh1 ribonuclease/angiogenin inhibitor 1 decreases expression ISO Zearalenone results in decreased expression of RNH1 protein CTD PMID:25058043 NCBI chr 1:214,151,341...214,163,807
Ensembl chr 1:214,151,338...214,163,808
JBrowse link
G Rpl14 ribosomal protein L14 decreases expression ISO Zearalenone results in decreased expression of RPL14 mRNA CTD PMID:30138655 NCBI chr 8:129,240,528...129,243,400
Ensembl chr 8:129,240,528...129,243,402
JBrowse link
G Rpl23a ribosomal protein L23a decreases expression ISO Zearalenone results in decreased expression of RPL23A mRNA CTD PMID:30138655 NCBI chr10:65,441,295...65,443,981
Ensembl chr10:65,441,295...65,443,981
JBrowse link
G Rps5 ribosomal protein S5 decreases expression ISO Zearalenone results in decreased expression of RPS5 mRNA CTD PMID:30138655 NCBI chr 1:65,660,470...65,664,767
Ensembl chr 1:65,660,470...65,664,767
JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 multiple interactions
decreases phosphorylation
ISO 2-aminoethyl diphenylborinate inhibits the reaction [Zearalenone results in decreased phosphorylation of RPS6KB1 protein]; acadesine promotes the reaction [Zearalenone results in decreased phosphorylation of RPS6KB1 protein]; Acetylcysteine inhibits the reaction [Zearalenone results in decreased phosphorylation of RPS6KB1 protein]; dorsomorphin inhibits the reaction [Zearalenone results in decreased phosphorylation of RPS6KB1 protein]; HERPUD1 protein inhibits the reaction [Zearalenone results in decreased phosphorylation of RPS6KB1 protein] CTD PMID:30394307 PMID:31982503 NCBI chr10:73,824,200...73,865,503
Ensembl chr10:73,824,202...73,865,364
JBrowse link
G Rps8 ribosomal protein S8 decreases expression ISO Zearalenone results in decreased expression of RPS8 mRNA CTD PMID:30138655 NCBI chr 5:136,020,941...136,023,511
Ensembl chr 5:136,020,941...136,023,511
JBrowse link
G RragB Ras-related GTP binding B decreases expression ISO Zearalenone results in decreased expression of RRAGB mRNA CTD PMID:19371625 NCBI chr  X:19,085,913...19,135,049
Ensembl chr  X:19,336,372...19,369,746
Ensembl chr  X:19,336,372...19,369,746
JBrowse link
G S100g S100 calcium binding protein G increases expression EXP Zearalenone results in increased expression of S100G mRNA CTD PMID:17557909 NCBI chr  X:33,442,820...33,445,714
Ensembl chr  X:33,443,186...33,445,709
JBrowse link
G S1pr3 sphingosine-1-phosphate receptor 3 increases expression ISO Zearalenone results in increased expression of S1PR3 mRNA CTD PMID:19371625 NCBI chr17:13,799,383...13,812,877
Ensembl chr17:13,799,383...13,812,704
JBrowse link
G Samm50 SAMM50 sorting and assembly machinery component increases expression ISO Zearalenone results in increased expression of SAMM50 protein CTD PMID:25058043 NCBI chr 7:125,058,966...125,082,506
Ensembl chr 7:125,058,897...125,082,505
JBrowse link
G Sat1 spermidine/spermine N1-acetyl transferase 1 decreases expression ISO Zearalenone results in decreased expression of SAT1 mRNA CTD PMID:19371625 NCBI chr  X:43,626,480...43,629,767
Ensembl chr  X:43,625,169...43,629,765
JBrowse link
G Serbp1 Serpine1 mRNA binding protein 1 decreases expression ISO Zearalenone results in decreased expression of SERBP1 protein CTD PMID:25058043 NCBI chr 4:98,027,563...98,044,717
Ensembl chr 4:98,027,554...98,044,566
JBrowse link
G Serpine1 serpin family E member 1 multiple interactions ISO [Zearalenone co-treated with Aflatoxin B1] results in increased expression of SERPINE1 mRNA CTD PMID:28965971 NCBI chr12:22,641,104...22,651,482
Ensembl chr12:22,641,104...22,651,482
JBrowse link
G Sf3b5 splicing factor 3b, subunit 5 increases expression ISO Zearalenone results in increased expression of SF3B5 mRNA CTD PMID:19371625 NCBI chr 1:7,101,715...7,102,427
Ensembl chr 1:7,101,715...7,102,426
JBrowse link
G Sftpd surfactant protein D increases expression EXP Zearalenone results in increased expression of SFTPD mRNA CTD PMID:17557909 NCBI chr16:18,753,535...18,766,100
Ensembl chr16:18,745,458...18,766,174
JBrowse link
G Siah1 siah E3 ubiquitin protein ligase 1 decreases expression ISO Zearalenone results in decreased expression of SIAH1 mRNA CTD PMID:19371625 NCBI chr19:21,372,163...21,395,773
Ensembl chr19:21,372,163...21,395,767
JBrowse link
G Slc1a5 solute carrier family 1 member 5 increases expression ISO Zearalenone results in increased expression of SLC1A5 mRNA CTD PMID:19371625 NCBI chr 1:78,710,686...78,724,789
Ensembl chr 1:78,710,539...78,724,794
JBrowse link
G Slc2a2 solute carrier family 2 member 2 increases expression ISO Zearalenone results in increased expression of SLC2A2 mRNA CTD PMID:32119988 NCBI chr 2:114,413,427...114,445,418
Ensembl chr 2:114,413,410...114,445,395
JBrowse link
G Slc31a1 solute carrier family 31 member 1 increases expression ISO Zearalenone results in increased expression of SLC31A1 mRNA CTD PMID:19371625 NCBI chr 5:78,222,504...78,249,358
Ensembl chr 5:78,222,504...78,249,358
JBrowse link
G Slc39a6 solute carrier family 39 member 6 increases expression ISO Zearalenone results in increased expression of SLC39A6 mRNA CTD PMID:28965971 NCBI chr18:16,523,450...16,543,992
Ensembl chr18:16,522,982...16,543,992
JBrowse link
G Slc3a2 solute carrier family 3 member 2 increases expression ISO Zearalenone results in increased expression of SLC3A2 mRNA CTD PMID:19371625 NCBI chr 1:224,906,566...224,921,029
Ensembl chr 1:224,906,554...224,921,092
JBrowse link
G Slc41a3 solute carrier family 41, member 3 decreases expression ISO Zearalenone results in decreased expression of SLC41A3 mRNA CTD PMID:19371625 NCBI chr 4:123,467,552...123,513,447
Ensembl chr 4:123,467,549...123,510,217
JBrowse link
G Slc6a6 solute carrier family 6 member 6 increases expression ISO Zearalenone results in increased expression of SLC6A6 mRNA CTD PMID:19371625 NCBI chr 4:123,638,619...123,713,469
Ensembl chr 4:123,642,210...123,713,464
JBrowse link
G Slc7a11 solute carrier family 7 member 11 increases expression ISO Zearalenone results in increased expression of SLC7A11 mRNA CTD PMID:25424538 NCBI chr 2:139,453,774...139,528,479
Ensembl chr 2:139,453,774...139,528,162
JBrowse link
G Slc7a5 solute carrier family 7 member 5 increases expression ISO Zearalenone results in increased expression of SLC7A5 mRNA CTD PMID:19371625 NCBI chr19:54,693,959...54,722,563
Ensembl chr19:54,693,959...54,722,563
JBrowse link
G Slit2 slit guidance ligand 2 decreases expression ISO Zearalenone results in decreased expression of SLIT2 mRNA CTD PMID:28965971 NCBI chr14:66,831,848...67,171,491
Ensembl chr14:66,831,848...67,170,361
JBrowse link
G Smad3 SMAD family member 3 increases expression
multiple interactions
ISO Zearalenone results in increased expression of SMAD3 mRNA
[Tamoxifen co-treated with Zearalenone] results in increased expression of SMAD3 mRNA
CTD PMID:30138655 NCBI chr 8:68,569,530...68,678,349
Ensembl chr 8:68,569,530...68,678,349
JBrowse link
G Smpdl3b sphingomyelin phosphodiesterase, acid-like 3B multiple interactions ISO [Zearalenone co-treated with CGA protein] results in decreased expression of SMPDL3B protein CTD PMID:25058043 NCBI chr 5:150,925,150...150,946,994
Ensembl chr 5:150,925,370...150,949,931
JBrowse link
G Snai2 snail family transcriptional repressor 2 decreases expression ISO Zearalenone results in decreased expression of SNAI2 mRNA CTD PMID:28965971 NCBI chr11:90,404,421...90,406,730
Ensembl chr11:90,403,333...90,406,797
JBrowse link
G Sohlh2 spermatogenesis and oogenesis specific basic helix-loop-helix 2 decreases expression ISO Zearalenone results in decreased expression of SOHLH2 mRNA CTD PMID:28089945 NCBI chr 2:144,591,755...144,614,065
Ensembl chr 2:144,591,755...144,614,064
JBrowse link
G Sox9 SRY-box transcription factor 9 decreases expression ISO Zearalenone results in decreased expression of SOX9 mRNA CTD PMID:24412631 NCBI chr10:101,288,528...101,294,030
Ensembl chr10:101,288,489...101,293,379
JBrowse link
G Spata2 spermatogenesis associated 2 decreases expression ISO Zearalenone results in decreased expression of SPATA2 mRNA CTD PMID:24412631 NCBI chr 3:164,229,211...164,239,483
Ensembl chr 3:164,230,852...164,239,250
JBrowse link
G Spsb3 splA/ryanodine receptor domain and SOCS box containing 3 decreases expression ISO Zearalenone results in decreased expression of SPSB3 mRNA CTD PMID:19371625 NCBI chr10:14,248,199...14,253,815
Ensembl chr10:14,248,399...14,253,815
JBrowse link
G Sqle squalene epoxidase decreases expression ISO Zearalenone results in decreased expression of SQLE mRNA CTD PMID:19371625 PMID:25424538 NCBI chr 7:99,609,929...99,624,803
Ensembl chr 7:99,609,191...99,624,732
JBrowse link
G Sqstm1 sequestosome 1 increases expression
decreases expression
EXP
ISO
Zearalenone results in increased expression of SQSTM1 protein
Zearalenone results in decreased expression of SQSTM1 protein
CTD PMID:31586597 PMID:31982503 NCBI chr10:35,704,728...35,716,316
Ensembl chr10:35,704,730...35,716,294
JBrowse link
G Srd5a1 steroid 5 alpha-reductase 1 decreases expression
decreases activity
EXP Zearalenone results in decreased expression of SRD5A1 mRNA
Zearalenone results in decreased activity of SRD5A1 protein
CTD PMID:29669061 NCBI chr 1:36,320,504...36,354,694
Ensembl chr 1:36,320,461...36,354,756
JBrowse link
G Ssc4d scavenger receptor cysteine rich family member with 4 domains decreases expression ISO Zearalenone results in decreased expression of SSC4D mRNA CTD PMID:19371625 NCBI chr12:23,752,823...23,769,466
Ensembl chr12:23,752,844...23,762,877
JBrowse link
G Star steroidogenic acute regulatory protein multiple interactions
decreases expression
increases expression
ISO
EXP
Colforsin affects the reaction [Zearalenone results in increased expression of STAR mRNA]
Zearalenone results in decreased expression of STAR mRNA; Zearalenone results in decreased expression of STAR protein
CTD PMID:24512812 PMID:26783879 PMID:29627501 NCBI chr16:71,036,204...71,040,847
Ensembl chr16:71,036,204...71,040,847
JBrowse link
G Stat5a signal transducer and activator of transcription 5A decreases expression ISO Zearalenone results in decreased expression of STAT5A mRNA CTD PMID:30138655 NCBI chr10:88,764,732...88,789,060
Ensembl chr10:88,764,732...88,789,057
JBrowse link
G Stk31 serine threonine kinase 31 decreases expression ISO Zearalenone results in decreased expression of STK31 protein CTD PMID:31419471 NCBI chr 4:79,055,493...79,153,849
Ensembl chr 4:79,055,280...79,153,831
JBrowse link
G Stoml2 stomatin like 2 increases expression ISO Zearalenone results in increased expression of STOML2 protein CTD PMID:25058043 NCBI chr 5:58,472,561...58,476,158
Ensembl chr 5:58,472,550...58,476,251
JBrowse link
G Stra8 stimulated by retinoic acid 8 decreases expression ISO Zearalenone results in decreased expression of STRA8 mRNA CTD PMID:28552778 NCBI chr 4:62,447,724...62,474,802
Ensembl chr 4:62,457,694...62,473,360
JBrowse link
G Sult1e1 sulfotransferase family 1E member 1 decreases activity ISO Zearalenone results in decreased activity of SULT1E1 protein CTD PMID:16914110 NCBI chr14:22,070,861...22,089,264
Ensembl chr14:22,072,024...22,089,248
JBrowse link
G Syap1 synapse associated protein 1 multiple interactions ISO [Zearalenone co-treated with CGA protein] results in decreased expression of SYAP1 protein CTD PMID:25058043 NCBI chr  X:33,528,071...33,562,584
Ensembl chr  X:33,528,081...33,562,589
JBrowse link
G Sycp1 synaptonemal complex protein 1 increases expression ISO Zearalenone results in increased expression of SYCP1 mRNA CTD PMID:24412631 NCBI chr 2:205,274,766...205,426,869
Ensembl chr 2:205,274,769...205,426,869
JBrowse link
G Sycp3 synaptonemal complex protein 3 decreases expression ISO Zearalenone results in decreased expression of SYCP3 mRNA; Zearalenone results in decreased expression of SYCP3 protein CTD PMID:24412631 PMID:28552778 PMID:31419471 NCBI chr 7:29,029,887...29,044,344
Ensembl chr 7:29,029,263...29,044,251
JBrowse link
G Taldo1 transaldolase 1 decreases expression ISO Zearalenone results in decreased expression of TALDO1 protein CTD PMID:25058043 NCBI chr 1:214,375,555...214,385,886
Ensembl chr 1:214,375,515...214,385,885
JBrowse link
G Tead3 TEA domain transcription factor 3 increases expression ISO Zearalenone results in increased expression of TEAD3 mRNA CTD PMID:30138655 NCBI chr20:7,911,562...7,930,949
Ensembl chr20:7,908,226...7,930,929
JBrowse link
G Tf transferrin decreases expression
affects expression
multiple interactions
ISO Zearalenone results in decreased expression of TF mRNA
Zearalenone affects the expression of TF mRNA
[deoxynivalenol co-treated with Zearalenone] affects the expression of TF mRNA; [deoxynivalenol co-treated with Zearalenone] results in increased expression of TF mRNA
CTD PMID:28865950 PMID:28935499 NCBI chr 8:111,694,570...111,721,275
Ensembl chr 8:111,673,547...111,721,333
JBrowse link
G Tff3 trefoil factor 3 increases expression ISO Zearalenone results in increased expression of TFF3 mRNA CTD PMID:28965971 NCBI chr20:9,850,800...9,855,481
Ensembl chr20:9,850,803...9,855,481
JBrowse link
G Tgfa transforming growth factor alpha increases expression ISO Zearalenone results in increased expression of TGFA mRNA CTD PMID:19371625 NCBI chr 4:117,961,877...118,045,923
Ensembl chr 4:117,962,319...118,046,344
JBrowse link
G Tgfb2 transforming growth factor, beta 2 decreases expression ISO Zearalenone results in decreased expression of TGFB2 mRNA CTD PMID:27862621 PMID:29758222 NCBI chr13:105,039,639...105,142,010
Ensembl chr13:105,039,853...105,141,030
JBrowse link
G Th tyrosine hydroxylase decreases expression ISO Zearalenone results in decreased expression of TH mRNA CTD PMID:24412706 NCBI chr 1:216,073,034...216,080,287
Ensembl chr 1:216,073,031...216,080,287
JBrowse link
G Thbs1 thrombospondin 1 increases expression
decreases expression
ISO Zearalenone results in increased expression of THBS1 mRNA
Zearalenone results in decreased expression of THBS1 mRNA
CTD PMID:19371625 PMID:28965971 NCBI chr 3:109,862,120...109,873,466
Ensembl chr 3:109,862,117...109,873,466
JBrowse link
G Thrb thyroid hormone receptor beta multiple interactions
decreases activity
ISO [15-acetyldeoxynivalenol co-treated with 3-acetyldeoxynivalenol co-treated with deoxynivalenol co-treated with zearalenol co-treated with Zearalenone] results in decreased activity of THRB protein; Zearalenone inhibits the reaction [Triiodothyronine results in increased activity of THRB protein]
Zearalenone results in decreased activity of THRB protein
CTD PMID:27481073 PMID:31077750 NCBI chr15:8,890,578...9,239,815
Ensembl chr15:8,890,578...9,086,282
JBrowse link
G Tinf2 TERF1 interacting nuclear factor 2 decreases expression ISO Zearalenone results in decreased expression of TINF2 mRNA CTD PMID:19371625 NCBI chr15:34,358,697...34,365,085
Ensembl chr15:34,360,974...34,364,081
JBrowse link
G Tkt transketolase decreases expression ISO Zearalenone results in decreased expression of TKT protein CTD PMID:25058043 NCBI chr16:6,609,670...6,634,608
Ensembl chr16:6,609,668...6,634,595
JBrowse link
G Tln1 talin 1 multiple interactions ISO [Zearalenone co-treated with CGA protein] results in increased expression of TLN1 protein CTD PMID:25058043 NCBI chr 5:59,033,635...59,063,592
Ensembl chr 5:59,033,636...59,063,592
JBrowse link
G Tlr3 toll-like receptor 3 increases expression ISO Zearalenone results in increased expression of TLR3 mRNA CTD PMID:27757495 NCBI chr16:50,016,466...50,031,011
Ensembl chr16:50,016,857...50,031,214
JBrowse link
G Tm6sf1 transmembrane 6 superfamily member 1 increases expression ISO Zearalenone results in increased expression of TM6SF1 mRNA CTD PMID:25424538 NCBI chr 1:143,657,607...143,703,829
Ensembl chr 1:143,661,521...143,703,759
JBrowse link
G Tmem121 transmembrane protein 121 decreases expression ISO Zearalenone results in decreased expression of TMEM121 mRNA CTD PMID:19371625 NCBI chr 6:137,994,675...138,002,897
Ensembl chr 6:137,997,335...137,998,291
JBrowse link
G Tmem54 transmembrane protein 54 decreases expression ISO Zearalenone results in decreased expression of TMEM54 mRNA CTD PMID:19371625 NCBI chr 5:147,288,700...147,295,191
Ensembl chr 5:147,288,723...147,296,702
JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression
ISO
EXP
Lipopolysaccharides promotes the reaction [Zearalenone results in increased expression of TNF mRNA]; lycopene inhibits the reaction [Zearalenone results in increased expression of TNF]
[Lipopolysaccharides co-treated with Zearalenone] results in increased secretion of TNF protein
Zearalenone results in increased expression of TNF protein
3-methyladenine promotes the reaction [[Zearalenone co-treated with Lipopolysaccharides] results in increased expression of TNF protein]; [Zearalenone co-treated with Lipopolysaccharides] results in increased expression of TNF mRNA; [Zearalenone co-treated with Lipopolysaccharides] results in increased expression of TNF protein; MCC-950 inhibits the reaction [[Zearalenone co-treated with Lipopolysaccharides] results in increased expression of TNF mRNA]; MCC-950 inhibits the reaction [[Zearalenone co-treated with Lipopolysaccharides] results in increased expression of TNF protein]; NLRP3 protein promotes the reaction [[Zearalenone co-treated with Lipopolysaccharides] results in increased expression of TNF protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Zearalenone co-treated with Lipopolysaccharides] results in increased expression of TNF mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Zearalenone results in increased expression of TNF protein]; Sirolimus inhibits the reaction [[Zearalenone co-treated with Lipopolysaccharides] results in increased expression of TNF protein]
CTD PMID:16687389 PMID:25682699 PMID:31586597 PMID:32328699 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnfrsf25 TNF receptor superfamily member 25 decreases expression ISO Zearalenone results in decreased expression of TNFRSF25 mRNA CTD PMID:19371625 NCBI chr 5:169,288,419...169,293,137
Ensembl chr 5:169,288,871...169,293,137
JBrowse link
G Tnfsf10 TNF superfamily member 10 increases expression ISO Zearalenone results in increased expression of TNFSF10 mRNA CTD PMID:27757495 NCBI chr 2:113,008,008...113,026,899
Ensembl chr 2:113,007,549...113,026,899
JBrowse link
G Tnnt1 troponin T1, slow skeletal type decreases expression ISO Zearalenone results in decreased expression of TNNT1 mRNA CTD PMID:19371625 NCBI chr 1:72,889,270...72,899,629
Ensembl chr 1:72,889,270...72,899,659
JBrowse link
G Tomm40 translocase of outer mitochondrial membrane 40 increases expression ISO Zearalenone results in increased expression of TOMM40 protein CTD PMID:25058043 NCBI chr 1:80,617,749...80,630,253
Ensembl chr 1:80,618,154...80,630,038
JBrowse link
G Tomm70 translocase of outer mitochondrial membrane 70 increases expression ISO Zearalenone results in increased expression of TOMM70A protein CTD PMID:25058043 NCBI chr11:45,477,053...45,511,409
Ensembl chr11:45,480,250...45,510,961
JBrowse link
G Tp53 tumor protein p53 decreases expression
multiple interactions
increases expression
ISO Zearalenone results in decreased expression of TRP53 mRNA
[Zearalenone co-treated with Aflatoxin B1] promotes the reaction [deoxynivalenol results in increased expression of TP53 mRNA]
Zearalenone results in increased expression of TP53 mRNA
CTD PMID:24412631 PMID:30668976 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Tp73 tumor protein p73 multiple interactions ISO [Zearalenone co-treated with Aflatoxin B1] results in increased expression of TP73 mRNA CTD PMID:28965971 NCBI chr 5:171,355,876...171,415,354
Ensembl chr 5:171,355,876...171,415,354
JBrowse link
G Trap1 TNF receptor-associated protein 1 increases expression ISO Zearalenone results in increased expression of TRAP1 protein CTD PMID:25058043 NCBI chr10:11,724,032...11,757,682
Ensembl chr10:11,724,032...11,757,681
JBrowse link
G Tsc22d1 TSC22 domain family, member 1 decreases expression ISO Zearalenone results in decreased expression of TSC22D1 mRNA CTD PMID:19371625 NCBI chr15:58,554,358...58,658,156
Ensembl chr15:58,554,374...58,658,153
JBrowse link
G Tsku tsukushi, small leucine rich proteoglycan increases expression ISO Zearalenone results in increased expression of TSKU mRNA CTD PMID:19371625 NCBI chr 1:163,317,281...163,328,697
Ensembl chr 1:163,317,282...163,328,591
JBrowse link
G Tspan1 tetraspanin 1 increases expression EXP Zearalenone results in increased expression of TSPAN1 mRNA CTD PMID:17557909 NCBI chr 5:135,019,206...135,032,412
Ensembl chr 5:135,019,778...135,025,084
JBrowse link
G Tspan10 tetraspanin 10 decreases expression ISO Zearalenone results in decreased expression of TSPAN10 mRNA CTD PMID:19371625 NCBI chr10:109,614,664...109,619,581
Ensembl chr10:109,614,965...109,618,807
JBrowse link
G Tspan12 tetraspanin 12 decreases expression ISO Zearalenone results in decreased expression of TSPAN12 mRNA CTD PMID:19371625 NCBI chr 4:48,852,823...48,953,240
Ensembl chr 4:48,852,827...48,928,372
JBrowse link
G Tst thiosulfate sulfurtransferase decreases expression ISO Zearalenone results in decreased expression of TST mRNA CTD PMID:30138655 NCBI chr 7:119,616,323...119,623,072
Ensembl chr 7:119,616,324...119,623,072
JBrowse link
G Twist1 twist family bHLH transcription factor 1 decreases expression ISO Zearalenone results in decreased expression of TWIST1 mRNA CTD PMID:28965971 NCBI chr 6:53,401,241...53,403,235
Ensembl chr 6:53,401,109...53,403,214
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 increases glucuronidation ISO UGT1A1 protein results in increased glucuronidation of Zearalenone CTD PMID:14557274 NCBI chr 9:95,295,701...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Ugt1a8 UDP glucuronosyltransferase family 1 member A8 increases glucuronidation ISO UGT1A8 protein results in increased glucuronidation of Zearalenone CTD PMID:14557274 NCBI chr 9:95,221,474...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Ugt1a9 UDP glucuronosyltransferase family 1 member A9 increases glucuronidation ISO UGT1A9 protein results in increased glucuronidation of Zearalenone CTD PMID:14557274 NCBI chr 9:95,161,157...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Ugt2b UDP glycosyltransferase 2 family, polypeptide B increases expression EXP Zearalenone results in increased expression of UGT2B mRNA CTD PMID:20607812 Ensembl chr14:22,375,955...22,534,720 JBrowse link
G Uqcrc2 ubiquinol cytochrome c reductase core protein 2 increases expression ISO Zearalenone results in increased expression of UQCRC2 protein CTD PMID:25058043 NCBI chr 1:190,555,177...190,585,741
Ensembl chr 1:190,555,177...190,585,734
JBrowse link
G Utp15 UTP15, small subunit processome component increases expression ISO Zearalenone results in increased expression of UTP15 mRNA CTD PMID:19371625 NCBI chr 2:28,351,925...28,370,315
Ensembl chr 2:28,353,854...28,370,261
JBrowse link
G Vat1 vesicle amine transport 1 increases expression ISO Zearalenone results in increased expression of VAT1 protein CTD PMID:25058043 NCBI chr10:89,366,898...89,374,516
Ensembl chr10:89,366,899...89,374,516
JBrowse link
G Vcpkmt valosin containing protein lysine methyltransferase decreases expression ISO Zearalenone results in decreased expression of VCPKMT mRNA CTD PMID:19371625 NCBI chr 6:91,880,342...91,884,336 JBrowse link
G Vegfa vascular endothelial growth factor A decreases expression
increases expression
ISO Zearalenone results in decreased expression of VEGFA mRNA
Zearalenone results in increased expression of VEGFA mRNA
CTD PMID:24412631 PMID:27757495 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link
G Vldlr very low density lipoprotein receptor increases expression ISO Zearalenone results in increased expression of VLDLR mRNA CTD PMID:25424538 NCBI chr 1:245,236,819...245,273,688
Ensembl chr 1:245,237,736...245,269,205
JBrowse link
G Vpreb1 V-set pre-B cell surrogate light chain 1 decreases expression ISO Zearalenone results in decreased expression of VPREB1 mRNA CTD PMID:25424538 NCBI chr11:88,376,256...88,377,133
Ensembl chr11:88,376,256...88,377,133
JBrowse link
G Wnt7a Wnt family member 7A decreases expression ISO Zearalenone results in decreased expression of WNT7A mRNA CTD PMID:16534752 NCBI chr 4:122,994,425...123,040,609
Ensembl chr 4:122,994,425...123,040,609
JBrowse link
G Wt1 WT1 transcription factor decreases expression ISO Zearalenone results in decreased expression of WT1 mRNA CTD PMID:24412631 NCBI chr 3:95,133,221...95,180,574
Ensembl chr 3:95,133,713...95,180,564
JBrowse link
G Wwp2 WW domain containing E3 ubiquitin protein ligase 2 decreases expression ISO Zearalenone results in decreased expression of WWP2 mRNA CTD PMID:19371625 NCBI chr19:39,543,246...39,614,624
Ensembl chr19:39,543,242...39,614,625
JBrowse link
G Wwtr1 WW domain containing transcription regulator 1 increases expression ISO Zearalenone results in increased expression of WWTR1 mRNA; Zearalenone results in increased expression of WWTR1 protein CTD PMID:30138655 NCBI chr 2:147,577,149...147,693,033
Ensembl chr 2:147,577,089...147,693,082
JBrowse link
G Xbp1 X-box binding protein 1 increases expression ISO Zearalenone results in increased expression of XBP1 mRNA CTD PMID:28965971 NCBI chr14:85,753,736...85,758,820
Ensembl chr14:85,753,760...85,758,145
JBrowse link
G Yap1 Yes1 associated transcriptional regulator increases expression
increases phosphorylation
ISO Zearalenone results in increased expression of YAP1 mRNA
Zearalenone results in increased phosphorylation of YAP1 protein
CTD PMID:30138655 NCBI chr 8:6,133,014...6,204,240
Ensembl chr 8:6,135,493...6,203,579
JBrowse link
G Ykt6 YKT6 v-SNARE homolog multiple interactions ISO [Zearalenone co-treated with CGA protein] results in increased expression of YKT6 protein CTD PMID:25058043 NCBI chr14:86,196,018...86,207,057
Ensembl chr14:86,195,892...86,205,712
JBrowse link
G Zkscan2 zinc finger with KRAB and SCAN domains 2 increases expression ISO Zearalenone results in increased expression of ZKSCAN2 mRNA CTD PMID:19371625 NCBI chr 1:193,440,749...193,459,755
Ensembl chr 1:193,437,614...193,459,396
JBrowse link
G Zmym3 zinc finger MYM-type containing 3 increases expression ISO Zearalenone results in increased expression of ZMYM3 mRNA CTD PMID:19371625 NCBI chr  X:71,298,737...71,313,529
Ensembl chr  X:71,299,662...71,313,542
JBrowse link
G Zmynd10 zinc finger, MYND-type containing 10 decreases expression ISO Zearalenone results in decreased expression of ZMYND10 mRNA CTD PMID:19371625 NCBI chr 8:116,302,513...116,306,871
Ensembl chr 8:116,302,513...116,306,870
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19875
    role 19825
      biological role 19825
        biochemical role 19360
          metabolite 19341
            eukaryotic metabolite 18998
              fungal metabolite 17466
                zearalenone 470
Path 2
Term Annotations click to browse term
  CHEBI ontology 19875
    subatomic particle 19873
      composite particle 19873
        hadron 19873
          baryon 19873
            nucleon 19873
              atomic nucleus 19873
                atom 19873
                  main group element atom 19763
                    p-block element atom 19763
                      carbon group element atom 19668
                        carbon atom 19657
                          organic molecular entity 19657
                            organic group 18569
                              organic divalent group 18560
                                organodiyl group 18560
                                  carbonyl group 18468
                                    carbonyl compound 18468
                                      carboxylic ester 14383
                                        lactone 6001
                                          macrocyclic lactone 1743
                                            macrolide 1612
                                              zearalenone 470
paths to the root