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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:Xylometazoline
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Accession:CHEBI:10082 term browser browse the term
Definition:An alkylbenzene that has formula C16H24N2.
Synonyms:related_synonym: Formula=C16H24N2;   InChI=1S/C16H24N2/c1-11-8-13(16(3,4)5)9-12(2)14(11)10-15-17-6-7-18-15/h8-9H,6-7,10H2,1-5H3,(H,17,18);   InChIKey=HUCJFAOMUPXHDK-UHFFFAOYSA-N;   SMILES=Cc1cc(cc(C)c1CC1=NCCN1)C(C)(C)C;   otrivine;   rhinoxilin;   xylometazoline HCl;   xylometazoline hydrochloride
 xref: CAS:526-36-3;   Drug_Central:3658;   HMDB:HMDB0015640;   KEGG:C07913;   KEGG:D08684;   LINCS:LSM-5262
 xref_mesh: MESH:C009695


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Xylometazoline term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adra1a adrenoceptor alpha 1A affects binding
multiple interactions
ISO xylometazoline binds to ADRA1A protein
xylometazoline inhibits the reaction [ADRA1A protein binds to Prazosin]
CTD PMID:20030735 NCBI chr15:43,296,997...43,398,314
Ensembl chr15:43,298,794...43,392,451
JBrowse link
G Adra1b adrenoceptor alpha 1B affects binding
multiple interactions
ISO xylometazoline binds to ADRA1B protein
xylometazoline inhibits the reaction [ADRA1B protein binds to Prazosin]
CTD PMID:20030735 NCBI chr10:29,392,762...29,450,644
Ensembl chr10:29,392,762...29,450,644
JBrowse link
G Adra1d adrenoceptor alpha 1D affects binding
multiple interactions
ISO xylometazoline binds to ADRA1D protein
xylometazoline inhibits the reaction [ADRA1D protein binds to Prazosin]
CTD PMID:20030735 NCBI chr 3:124,129,558...124,145,566
Ensembl chr 3:124,129,558...124,145,566
JBrowse link
G Adra2a adrenoceptor alpha 2A affects binding
multiple interactions
ISO xylometazoline binds to ADRA2A protein
xylometazoline inhibits the reaction [ADRA2A protein binds to 2-methoxyidazoxan]
CTD PMID:20030735 NCBI chr 1:274,766,283...274,769,083
Ensembl chr 1:274,766,283...274,769,081
JBrowse link
G Adra2b adrenoceptor alpha 2B multiple interactions ISO [xylometazoline binds to and results in increased activity of ADRA2B protein] which results in increased abundance of Calcium; xylometazoline binds to and results in increased activity of ADRA2B protein; xylometazoline inhibits the reaction [ADRA2B protein binds to 2-methoxyidazoxan] CTD PMID:20030735 NCBI chr 3:119,805,941...119,809,987
Ensembl chr 3:119,805,941...119,809,987
JBrowse link
G Adra2c adrenoceptor alpha 2C affects binding
multiple interactions
ISO xylometazoline binds to ADRA2C protein
xylometazoline inhibits the reaction [ADRA2C protein binds to 2-methoxyidazoxan]
CTD PMID:20030735 NCBI chr14:80,730,307...80,732,010
Ensembl chr14:80,730,307...80,732,010
JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO xylometazoline inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,318,025...48,360,219
Ensembl chr 1:48,317,995...48,360,261
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19771
    role 19716
      chemical role 19256
        environmental contaminant 18595
          benzene 5643
            alkylbenzene 3365
              Xylometazoline 7
Path 2
Term Annotations click to browse term
  CHEBI ontology 19771
    subatomic particle 19770
      composite particle 19770
        hadron 19770
          baryon 19770
            nucleon 19770
              atomic nucleus 19770
                atom 19770
                  main group element atom 19658
                    main group molecular entity 19658
                      s-block molecular entity 19423
                        hydrogen molecular entity 19416
                          hydrides 18755
                            organic hydride 18356
                              organic fundamental parent 18356
                                hydrocarbon 18074
                                  cyclic hydrocarbon 17089
                                    monocyclic hydrocarbon 5816
                                      annulene 5643
                                        aromatic annulene 5643
                                          benzene 5643
                                            alkylbenzene 3365
                                              Xylometazoline 7
paths to the root