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G |
A1BG |
alpha-1-B glycoprotein |
decreases expression |
ISO |
Fenofibrate results in decreased expression of A1BG protein |
CTD |
PMID:20118634 |
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NCBI chr19:58,345,183...58,353,492
Ensembl chr19:58,345,178...58,353,492
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G |
AADAC |
arylacetamide deacetylase |
increases expression |
EXP |
Fenofibrate results in increased expression of AADAC mRNA |
CTD |
PMID:25572481 |
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NCBI chr 3:151,814,116...151,828,488
Ensembl chr 3:151,814,073...151,828,488
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G |
AARS1 |
alanyl-tRNA synthetase 1 |
increases expression |
ISO |
Fenofibrate results in increased expression of AARS1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr16:70,252,298...70,289,506
Ensembl chr16:70,251,983...70,289,707
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G |
ABCA1 |
ATP binding cassette subfamily A member 1 |
increases expression |
EXP ISO |
Fenofibrate results in increased expression of ABCA1 mRNA; Fenofibrate results in increased expression of ABCA1 protein |
CTD |
PMID:19201410 |
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NCBI chr 9:104,781,006...104,928,155
Ensembl chr 9:104,781,006...104,928,155
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G |
ABCB1 |
ATP binding cassette subfamily B member 1 |
multiple interactions |
EXP |
Fenofibrate inhibits the reaction [ABCB1 protein results in increased transport of Vincristine] |
CTD |
PMID:16316932 |
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NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323
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G |
ABCB11 |
ATP binding cassette subfamily B member 11 |
multiple interactions decreases expression decreases activity |
EXP ISO |
Fenofibrate inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid] Fenofibrate results in decreased expression of ABCB11 mRNA Fenofibrate results in decreased activity of ABCB11 protein |
CTD |
PMID:20829430 PMID:23956101 PMID:24014644 PMID:27765674 |
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NCBI chr 2:168,915,390...169,031,324
Ensembl chr 2:168,915,498...169,031,324
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G |
ABCB4 |
ATP binding cassette subfamily B member 4 |
increases expression |
ISO EXP |
Fenofibrate results in increased expression of ABCB4 mRNA |
CTD |
PMID:17118139 PMID:19118567 |
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NCBI chr 7:87,365,896...87,476,027
Ensembl chr 7:87,401,696...87,480,435
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G |
ABCB6 |
ATP binding cassette subfamily B member 6 (LAN blood group) |
decreases expression |
ISO |
Fenofibrate results in decreased expression of ABCB6 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 2:219,209,772...219,218,958
Ensembl chr 2:219,209,772...219,218,994
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G |
ABCB9 |
ATP binding cassette subfamily B member 9 |
increases expression |
ISO |
Fenofibrate results in increased expression of ABCB9 mRNA |
CTD |
PMID:25596134 |
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NCBI chr12:122,918,610...122,975,114
Ensembl chr12:122,920,951...122,981,649
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G |
ABCC2 |
ATP binding cassette subfamily C member 2 |
increases expression |
ISO |
Fenofibrate results in increased expression of ABCC2 mRNA |
CTD |
PMID:27765674 |
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NCBI chr10:99,782,640...99,852,594
Ensembl chr10:99,782,640...99,852,594
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G |
ABCC3 |
ATP binding cassette subfamily C member 3 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of ABCC3 mRNA |
CTD |
PMID:25596134 |
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NCBI chr17:50,634,881...50,692,253
Ensembl chr17:50,634,777...50,692,253
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G |
ABCC4 |
ATP binding cassette subfamily C member 4 (PEL blood group) |
increases expression |
ISO |
Fenofibrate results in increased expression of ABCC4 mRNA |
CTD |
PMID:27765674 |
|
NCBI chr13:95,019,835...95,301,451
Ensembl chr13:95,019,835...95,301,475
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G |
ABCD3 |
ATP binding cassette subfamily D member 3 |
increases expression |
ISO |
Fenofibrate results in increased expression of ABCD3 mRNA |
CTD |
PMID:17118139 |
|
NCBI chr 1:94,385,131...94,518,663
Ensembl chr 1:94,418,389...94,518,666
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G |
ABCG1 |
ATP binding cassette subfamily G member 1 |
increases expression |
ISO |
Fenofibrate results in increased expression of ABCG1 mRNA |
CTD |
PMID:25596134 |
|
NCBI chr21:42,199,689...42,297,244
Ensembl chr21:42,199,689...42,304,389
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G |
ABCG5 |
ATP binding cassette subfamily G member 5 |
increases expression |
ISO |
Fenofibrate results in increased expression of ABCG5 mRNA |
CTD |
PMID:27765674 |
|
NCBI chr 2:43,806,211...43,839,231
Ensembl chr 2:43,812,472...43,838,865
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G |
ABCG8 |
ATP binding cassette subfamily G member 8 |
increases expression |
ISO |
Fenofibrate results in increased expression of ABCG8 mRNA |
CTD |
PMID:27765674 |
|
NCBI chr 2:43,838,971...43,882,988
Ensembl chr 2:43,831,942...43,882,988
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G |
ABHD4 |
abhydrolase domain containing 4, N-acyl phospholipase B |
increases expression |
ISO |
Fenofibrate results in increased expression of ABHD4 mRNA |
CTD |
PMID:25596134 |
|
NCBI chr14:22,598,300...22,612,963
Ensembl chr14:22,598,290...22,612,963
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G |
ABI3BP |
ABI family member 3 binding protein |
decreases expression |
EXP |
Fenofibrate results in decreased expression of ABI3BP mRNA |
CTD |
PMID:25572481 |
|
NCBI chr 3:100,749,156...100,993,421
Ensembl chr 3:100,749,156...100,993,515
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G |
ACAA1 |
acetyl-CoA acyltransferase 1 |
affects expression increases expression multiple interactions |
ISO EXP |
Fenofibrate affects the expression of ACAA1A mRNA Fenofibrate results in increased expression of ACAA1 mRNA Fenofibrate results in increased expression of ACAA1 mRNA; Fenofibrate results in increased expression of ACAA1A mRNA Fenofibrate promotes the reaction [Pyrazinamide results in increased expression of ACAA1 mRNA]; Pyrazinamide promotes the reaction [Fenofibrate results in increased expression of ACAA1 mRNA] |
CTD |
PMID:20801182 PMID:24752549 PMID:27071702 PMID:32741897 |
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NCBI chr 3:38,122,715...38,137,127
Ensembl chr 3:38,103,129...38,137,242
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G |
ACAA2 |
acetyl-CoA acyltransferase 2 |
affects expression increases expression |
ISO EXP |
Fenofibrate affects the expression of ACAA2 mRNA Fenofibrate results in increased expression of ACAA2 mRNA Fenofibrate results in increased expression of ACAA2 mRNA; Fenofibrate results in increased expression of ACAA2 protein |
CTD |
PMID:20118634 PMID:20801182 PMID:25572481 PMID:27665778 PMID:32741897 |
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NCBI chr18:49,782,164...49,813,533
Ensembl chr18:49,782,164...49,813,953
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G |
ACACA |
acetyl-CoA carboxylase alpha |
multiple interactions decreases expression increases expression |
ISO EXP |
NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACACA mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACACA mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACACA mRNA] Fenofibrate inhibits the reaction [Dietary Fats results in increased expression of ACACA mRNA] Fenofibrate inhibits the reaction [[Fructose co-treated with Palmitic Acid] results in decreased expression of ACACA protein modified form]; Fenofibrate inhibits the reaction [[Fructose co-treated with Palmitic Acid] results in increased expression of ACACA protein] Fenofibrate results in decreased expression of ACACA protein |
CTD |
PMID:23063693 PMID:24752549 PMID:32730863 PMID:38216941 |
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NCBI chr17:37,084,992...37,406,836
Ensembl chr17:37,084,992...37,406,836
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G |
ACACB |
acetyl-CoA carboxylase beta |
multiple interactions increases expression |
ISO |
NR1H2 gene mutant form affects the reaction [Fenofibrate results in increased expression of ACACB mRNA]; NR1H3 gene mutant form affects the reaction [Fenofibrate results in increased expression of ACACB mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACACB mRNA] |
CTD |
PMID:17118139 PMID:23063693 |
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NCBI chr12:109,111,189...109,268,226
Ensembl chr12:109,116,587...109,268,226
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G |
ACADL |
acyl-CoA dehydrogenase long chain |
increases expression |
ISO |
Fenofibrate results in increased expression of ACADL mRNA |
CTD |
PMID:17690133 |
|
NCBI chr 2:210,187,923...210,225,447
Ensembl chr 2:210,187,126...210,225,447
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G |
ACADM |
acyl-CoA dehydrogenase medium chain |
increases expression multiple interactions |
ISO EXP |
Fenofibrate results in increased expression of ACADM mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of ACADM mRNA] |
CTD |
PMID:11798191 PMID:17690133 PMID:19124612 PMID:24752549 PMID:25572481 PMID:33408297 More...
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NCBI chr 1:75,724,709...75,763,679
Ensembl chr 1:75,724,431...75,787,575
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G |
ACADS |
acyl-CoA dehydrogenase short chain |
multiple interactions |
ISO |
Fenofibrate inhibits the reaction [ACADS protein affects the cleavage of CASP3 protein]; Fenofibrate inhibits the reaction [tert-Butylhydroperoxide results in decreased expression of ACADS mRNA]; Fenofibrate inhibits the reaction [tert-Butylhydroperoxide results in decreased expression of and results in decreased activity of ACADS protein] |
CTD |
PMID:26989860 |
|
NCBI chr12:120,725,826...120,740,008
Ensembl chr12:120,725,774...120,740,008
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G |
ACADVL |
acyl-CoA dehydrogenase very long chain |
increases expression |
ISO EXP |
Fenofibrate results in increased expression of ACADVL mRNA |
CTD |
PMID:17118139 PMID:24752549 PMID:27665778 |
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NCBI chr17:7,217,125...7,225,266
Ensembl chr17:7,217,125...7,225,266
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G |
ACAT1 |
acetyl-CoA acetyltransferase 1 |
multiple interactions increases expression |
ISO EXP |
[Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of ACAT1 mRNA Fenofibrate results in increased expression of ACAT1 mRNA |
CTD |
PMID:18253720 PMID:24752549 |
|
NCBI chr11:108,116,705...108,147,603
Ensembl chr11:108,116,695...108,148,957
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G |
ACLY |
ATP citrate lyase |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of ACLY mRNA PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACLY mRNA] |
CTD |
PMID:23063693 |
|
NCBI chr17:41,866,917...41,930,545
Ensembl chr17:41,866,917...41,930,542
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G |
ACO1 |
aconitase 1 |
increases expression |
ISO |
Fenofibrate results in increased expression of ACO1 mRNA |
CTD |
PMID:17264098 |
|
NCBI chr 9:32,384,643...32,454,769
Ensembl chr 9:32,384,603...32,454,769
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G |
ACO2 |
aconitase 2 |
increases expression |
EXP |
Fenofibrate results in increased expression of ACO2 mRNA |
CTD |
PMID:24752549 |
|
NCBI chr22:41,469,117...41,528,974
Ensembl chr22:41,447,830...41,529,273
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G |
ACOT1 |
acyl-CoA thioesterase 1 |
increases expression |
ISO |
Fenofibrate results in increased expression of ACOT1 mRNA |
CTD |
PMID:11798191 PMID:17690133 PMID:27665778 PMID:32741897 |
|
NCBI chr14:73,490,933...73,543,796
Ensembl chr14:73,537,143...73,543,796
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G |
ACOT2 |
acyl-CoA thioesterase 2 |
affects expression multiple interactions increases expression |
ISO |
Fenofibrate affects the expression of ACOT2 mRNA Fenofibrate results in increased expression of and results in increased activity of ACOT2 protein Fenofibrate results in increased expression of ACOT2 mRNA |
CTD |
PMID:16595124 PMID:20801182 PMID:27665778 PMID:32741897 |
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NCBI chr14:73,567,620...73,575,658
Ensembl chr14:73,567,620...73,575,658
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G |
ACOT4 |
acyl-CoA thioesterase 4 |
increases expression |
ISO |
Fenofibrate results in increased expression of ACOT4 mRNA |
CTD |
PMID:27665778 PMID:32741897 |
|
NCBI chr14:73,591,873...73,595,766
Ensembl chr14:73,591,873...73,595,766
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G |
ACOT7 |
acyl-CoA thioesterase 7 |
increases expression |
ISO |
Fenofibrate results in increased expression of ACOT7 mRNA |
CTD |
PMID:32741897 |
|
NCBI chr 1:6,264,272...6,393,767
Ensembl chr 1:6,264,269...6,393,767
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G |
ACOX1 |
acyl-CoA oxidase 1 |
affects expression multiple interactions increases expression |
ISO EXP |
Fenofibrate affects the expression of ACOX1 mRNA [Fenofibrate co-treated with Fatty Acids, Nonesterified] results in increased expression of ACOX1 protein; [Fenofibrate co-treated with Oleic Acid] results in increased expression of ACOX1 mRNA; Fenofibrate inhibits the reaction [Fatty Acids, Nonesterified results in decreased expression of ACOX1 mRNA]; Fenofibrate inhibits the reaction [Fatty Acids, Nonesterified results in decreased expression of ACOX1 protein]; Fenofibrate promotes the reaction [Fatty Acids, Nonesterified results in increased expression of ACOX1 mRNA]; PPARA protein promotes the reaction [Fenofibrate results in increased expression of ACOX1 protein] Fenofibrate results in increased expression of ACOX1 mRNA; Fenofibrate results in increased expression of ACOX1 protein Fenofibrate inhibits the reaction [Zoledronic Acid results in decreased expression of ACOX1 mRNA]; NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACOX1 mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACOX1 mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACOX1 mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACOX1 protein] [Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of ACOX1 mRNA |
CTD |
PMID:16707586 PMID:17118139 PMID:17690133 PMID:18253720 PMID:18775883 PMID:19395589 PMID:20801182 PMID:22301950 PMID:23063693 PMID:24534255 PMID:24735863 PMID:24752549 PMID:24986865 PMID:25572481 PMID:28871336 PMID:30611848 PMID:32741897 More...
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NCBI chr17:75,941,507...75,979,166
Ensembl chr17:75,941,507...75,979,177
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G |
ACOX2 |
acyl-CoA oxidase 2 |
multiple interactions |
ISO |
Fenofibrate inhibits the reaction [zoledronic acid results in decreased expression of ACOX2 mRNA] |
CTD |
PMID:28871336 |
|
NCBI chr 3:58,505,136...58,537,190
Ensembl chr 3:58,505,136...58,537,283
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G |
ACSL1 |
acyl-CoA synthetase long chain family member 1 |
increases expression multiple interactions decreases expression affects expression |
ISO EXP |
Fenofibrate results in increased expression of ACSL1 mRNA; Fenofibrate results in increased expression of ACSL1 protein PPARA protein promotes the reaction [Fenofibrate results in increased expression of ACSL1 protein] PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACSL1 mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACSL1 protein] Fenofibrate results in decreased expression of ACSL1 protein Fenofibrate affects the expression of ACSL1 mRNA |
CTD |
PMID:10600944 PMID:17118139 PMID:20118634 PMID:20801182 PMID:24752549 PMID:25596134 PMID:32741897 More...
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NCBI chr 4:184,755,595...184,826,594
Ensembl chr 4:184,755,595...184,826,818
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G |
ACSL3 |
acyl-CoA synthetase long chain family member 3 |
increases expression |
ISO |
Fenofibrate results in increased expression of ACSL3 mRNA |
CTD |
PMID:32741897 |
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NCBI chr 2:222,861,036...222,944,639
Ensembl chr 2:222,860,942...222,944,639
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G |
ACSL4 |
acyl-CoA synthetase long chain family member 4 |
increases expression |
ISO |
Fenofibrate results in increased expression of ACSL4 mRNA |
CTD |
PMID:17118139 |
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NCBI chr X:109,641,335...109,733,257
Ensembl chr X:109,624,244...109,733,403
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G |
ACSL5 |
acyl-CoA synthetase long chain family member 5 |
increases expression |
ISO |
Fenofibrate results in increased expression of ACSL5 mRNA |
CTD |
PMID:17118139 |
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NCBI chr10:112,374,116...112,428,376
Ensembl chr10:112,374,116...112,428,379
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G |
ACSL6 |
acyl-CoA synthetase long chain family member 6 |
increases expression |
ISO |
Fenofibrate results in increased expression of ACSL6 mRNA |
CTD |
PMID:16595124 |
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NCBI chr 5:131,949,973...132,012,213
Ensembl chr 5:131,949,973...132,012,243
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G |
ACSS2 |
acyl-CoA synthetase short chain family member 2 |
decreases expression |
EXP |
Fenofibrate results in decreased expression of ACSS2 mRNA |
CTD |
PMID:25572481 |
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NCBI chr20:34,874,989...34,927,959
Ensembl chr20:34,872,146...34,927,962
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G |
ACTA2 |
actin alpha 2, smooth muscle |
multiple interactions |
ISO EXP |
Fenofibrate inhibits the reaction [zoledronic acid results in increased expression of ACTA2 protein] Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 mRNA] |
CTD |
PMID:28871336 PMID:32613381 |
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NCBI chr10:88,935,074...88,991,337
Ensembl chr10:88,934,822...88,991,339
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G |
ADAM22 |
ADAM metallopeptidase domain 22 |
increases expression |
ISO |
Fenofibrate results in increased expression of ADAM22 mRNA |
CTD |
PMID:32741897 |
|
NCBI chr 7:87,934,251...88,202,889
Ensembl chr 7:87,934,143...88,202,889
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G |
ADCY1 |
adenylate cyclase 1 |
decreases expression |
EXP |
Fenofibrate results in decreased expression of ADCY1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 7:45,574,140...45,723,116
Ensembl chr 7:45,574,140...45,723,116
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G |
ADH1C |
alcohol dehydrogenase 1C (class I), gamma polypeptide |
decreases expression |
EXP |
Fenofibrate results in decreased expression of ADH1C mRNA |
CTD |
PMID:25572481 |
|
NCBI chr 4:99,336,497...99,352,746
Ensembl chr 4:99,336,497...99,352,746
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G |
ADH4 |
alcohol dehydrogenase 4 (class II), pi polypeptide |
decreases expression |
EXP |
Fenofibrate results in decreased expression of ADH4 mRNA |
CTD |
PMID:25572481 |
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NCBI chr 4:99,123,658...99,144,297
Ensembl chr 4:99,123,657...99,157,792
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G |
ADIPOQ |
adiponectin, C1Q and collagen domain containing |
increases expression multiple interactions |
EXP |
Fenofibrate results in increased expression of ADIPOQ protein [candesartan co-treated with Fenofibrate] results in increased expression of ADIPOQ protein; Fenofibrate inhibits the reaction [Fatty Acids, Nonesterified results in decreased expression of ADIPOQ protein] |
CTD |
PMID:16443859 PMID:24735863 |
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NCBI chr 3:186,842,710...186,858,463
Ensembl chr 3:186,842,704...186,858,463
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G |
ADIPOR2 |
adiponectin receptor 2 |
increases expression |
ISO |
Fenofibrate results in increased expression of ADIPOR2 mRNA |
CTD |
PMID:16306350 |
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NCBI chr12:1,691,070...1,788,674
Ensembl chr12:1,688,574...1,788,674
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G |
AGRN |
agrin |
decreases expression |
ISO |
Fenofibrate results in decreased expression of AGRN mRNA |
CTD |
PMID:25596134 |
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NCBI chr 1:1,020,120...1,056,116
Ensembl chr 1:1,020,120...1,056,119
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G |
AGT |
angiotensinogen |
multiple interactions |
ISO |
Fenofibrate affects the reaction [[AHR protein affects the susceptibility to AGT protein] which affects the expression of EDN1 mRNA]; Fenofibrate affects the reaction [[AHR protein affects the susceptibility to AGT protein] which affects the expression of JUN mRNA]; Fenofibrate inhibits the reaction [AHR protein affects the reaction [AGT protein results in increased expression of COL1A1 mRNA]]; Fenofibrate inhibits the reaction [AHR protein affects the reaction [AGT protein results in increased expression of COL3A1 mRNA]]; Fenofibrate inhibits the reaction [AHR protein affects the reaction [AGT protein results in increased expression of VEGFA protein]] |
CTD |
PMID:31016362 |
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NCBI chr 1:230,702,523...230,745,583
Ensembl chr 1:230,690,776...230,745,576
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G |
AGXT2 |
alanine--glyoxylate aminotransferase 2 |
decreases expression |
EXP |
Fenofibrate results in decreased expression of AGXT2 mRNA |
CTD |
PMID:25572481 |
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NCBI chr 5:34,998,102...35,047,949
Ensembl chr 5:34,998,101...35,048,135
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G |
AHR |
aryl hydrocarbon receptor |
affects activity multiple interactions |
EXP ISO |
Fenofibrate affects the activity of AHR protein Fenofibrate affects the reaction [[AHR protein affects the susceptibility to AGT protein] which affects the expression of EDN1 mRNA]; Fenofibrate affects the reaction [[AHR protein affects the susceptibility to AGT protein] which affects the expression of JUN mRNA]; Fenofibrate inhibits the reaction [AHR protein affects the reaction [AGT protein results in increased expression of COL1A1 mRNA]]; Fenofibrate inhibits the reaction [AHR protein affects the reaction [AGT protein results in increased expression of COL3A1 mRNA]]; Fenofibrate inhibits the reaction [AHR protein affects the reaction [AGT protein results in increased expression of VEGFA protein]] |
CTD |
PMID:25596134 PMID:31016362 |
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NCBI chr 7:17,298,652...17,346,147
Ensembl chr 7:16,916,359...17,346,152
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G |
AIFM2 |
AIF family member 2 |
increases expression |
ISO EXP |
Fenofibrate results in increased expression of AIFM2 mRNA |
CTD |
PMID:25596134 |
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NCBI chr10:70,112,271...70,132,825
Ensembl chr10:70,098,223...70,132,934
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G |
AIG1 |
androgen induced 1 |
increases expression |
ISO |
Fenofibrate results in increased expression of AIG1 mRNA |
CTD |
PMID:32741897 |
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NCBI chr 6:143,059,213...143,343,883
Ensembl chr 6:143,060,496...143,341,058
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G |
AK4 |
adenylate kinase 4 |
affects expression |
ISO |
Fenofibrate affects the expression of AK4 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 1:65,147,552...65,232,145
Ensembl chr 1:65,147,549...65,232,145
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G |
AKR1B10 |
aldo-keto reductase family 1 member B10 |
multiple interactions decreases activity |
EXP |
Fenofibrate inhibits the reaction [AKR1B10 protein results in increased reduction of Daunorubicin]; Fenofibrate inhibits the reaction [AKR1B10 protein results in increased reduction of Glyceraldehyde] Fenofibrate results in decreased activity of AKR1B10 protein; Fenofibrate results in decreased activity of AKR1B10 protein mutant form |
CTD |
PMID:18325492 PMID:19028477 |
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NCBI chr 7:134,527,567...134,541,412
Ensembl chr 7:134,527,567...134,541,412
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G |
AKR1C2 |
aldo-keto reductase family 1 member C2 |
increases expression |
EXP |
Fenofibrate results in increased expression of AKR1C2 mRNA |
CTD |
PMID:25596134 |
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NCBI chr10:4,987,775...5,018,000
Ensembl chr10:4,987,775...5,018,031
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G |
ALB |
albumin |
multiple interactions |
EXP ISO |
dorsomorphin inhibits the reaction [Fenofibrate inhibits the reaction [ALB protein modified form results in increased expression of ICAM1 mRNA]]; dorsomorphin inhibits the reaction [Fenofibrate inhibits the reaction [ALB protein modified form results in increased expression of SELE mRNA]]; dorsomorphin inhibits the reaction [Fenofibrate inhibits the reaction [ALB protein modified form results in increased expression of VCAM1 mRNA]]; Fenofibrate inhibits the reaction [ALB protein modified form results in increased degradation of NFKBIA protein]; Fenofibrate inhibits the reaction [ALB protein modified form results in increased expression of ICAM1 mRNA]; Fenofibrate inhibits the reaction [ALB protein modified form results in increased expression of NFKB1 protein]; Fenofibrate inhibits the reaction [ALB protein modified form results in increased expression of RELA protein]; Fenofibrate inhibits the reaction [ALB protein modified form results in increased expression of SELE mRNA]; Fenofibrate inhibits the reaction [ALB protein modified form results in increased expression of VCAM1 mRNA]; PRKAA1 protein affects the reaction [Fenofibrate results in decreased susceptibility to ALB protein modified form] Fenofibrate inhibits the reaction [tyloxapol results in decreased expression of ALB mRNA] |
CTD |
PMID:20580385 PMID:37076581 |
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NCBI chr 4:73,404,287...73,421,482
Ensembl chr 4:73,397,114...73,421,482
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G |
ALDH1A2 |
aldehyde dehydrogenase 1 family member A2 |
increases expression |
ISO |
Fenofibrate results in increased expression of ALDH1A2 mRNA |
CTD |
PMID:17118139 |
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NCBI chr15:57,953,429...58,065,711
Ensembl chr15:57,953,424...58,497,866
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ALDH6A1 |
aldehyde dehydrogenase 6 family member A1 |
increases expression |
EXP |
Fenofibrate results in increased expression of ALDH6A1 mRNA |
CTD |
PMID:24752549 |
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NCBI chr14:74,056,847...74,084,453
Ensembl chr14:74,056,847...74,084,492
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G |
ALDOA |
aldolase, fructose-bisphosphate A |
increases expression |
ISO |
Fenofibrate results in increased expression of ALDOA mRNA |
CTD |
PMID:25596134 |
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NCBI chr16:30,064,279...30,070,420
Ensembl chr16:30,064,164...30,070,457
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G |
ALOX12 |
arachidonate 12-lipoxygenase, 12S type |
increases expression |
EXP |
Fenofibrate results in increased expression of ALOX12 mRNA |
CTD |
PMID:12759900 |
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NCBI chr17:6,996,049...7,010,754
Ensembl chr17:6,996,049...7,010,754
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G |
ALPK2 |
alpha kinase 2 |
increases expression |
EXP |
Fenofibrate results in increased expression of ALPK2 mRNA |
CTD |
PMID:25572481 |
|
NCBI chr18:58,481,247...58,629,091
Ensembl chr18:58,481,247...58,629,091
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G |
ALPL |
alkaline phosphatase, biomineralization associated |
decreases expression |
EXP |
Fenofibrate results in decreased expression of ALPL mRNA |
CTD |
PMID:25572481 |
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NCBI chr 1:21,508,984...21,578,410
Ensembl chr 1:21,509,397...21,578,410
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G |
ANAPC11 |
anaphase promoting complex subunit 11 |
multiple interactions decreases expression |
ISO |
PPARA protein affects the reaction [Fenofibrate results in decreased expression of ANAPC11 mRNA] |
CTD |
PMID:21318169 |
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NCBI chr17:81,890,790...81,900,533
Ensembl chr17:81,890,790...81,900,991
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G |
ANGPTL4 |
angiopoietin like 4 |
increases expression |
ISO EXP |
Fenofibrate results in increased expression of ANGPTL4 mRNA |
CTD |
PMID:17118139 PMID:25572481 PMID:25596134 PMID:27665778 PMID:32741897 |
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NCBI chr19:8,364,155...8,374,370
Ensembl chr19:8,363,289...8,374,370
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G |
ANKRA2 |
ankyrin repeat family A member 2 |
increases expression |
EXP |
Fenofibrate results in increased expression of ANKRA2 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 5:73,552,190...73,565,639
Ensembl chr 5:73,552,190...73,565,667
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G |
ANXA3 |
annexin A3 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of ANXA3 protein |
CTD |
PMID:20118634 |
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NCBI chr 4:78,551,770...78,610,447
Ensembl chr 4:78,551,747...78,610,451
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G |
APEX1 |
apurinic/apyrimidinic endodeoxyribonuclease 1 |
multiple interactions increases expression |
ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of APEX1 mRNA Fenofibrate results in increased expression of APEX1 mRNA |
CTD |
PMID:17264098 PMID:18253720 PMID:18775883 |
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NCBI chr14:20,455,226...20,457,767
Ensembl chr14:20,455,191...20,457,772
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G |
APOA1 |
apolipoprotein A1 |
decreases expression multiple interactions |
EXP ISO |
Fenofibrate results in decreased expression of APOA1 mRNA; Fenofibrate results in decreased expression of APOA1 protein [Fenofibrate co-treated with Pyrazinamide] results in increased expression of APOA1 mRNA Fenofibrate promotes the reaction [APOA1 protein results in increased secretion of Lipids]; PPARA protein affects the reaction [Fenofibrate promotes the reaction [APOA1 protein results in increased secretion of Lipids]] Fenofibrate promotes the reaction [APOA1 protein results in increased secretion of Lipids]; PPARA protein inhibits the reaction [Fenofibrate results in decreased expression of APOA1 mRNA] |
CTD |
PMID:7983038 PMID:19201410 PMID:19445040 PMID:27071702 |
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NCBI chr11:116,835,751...116,837,622
Ensembl chr11:116,835,751...116,837,622
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G |
APOA4 |
apolipoprotein A4 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of APOA4 mRNA |
CTD |
PMID:11798191 |
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NCBI chr11:116,820,700...116,823,304
Ensembl chr11:116,820,700...116,823,304
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G |
APOB |
apolipoprotein B |
decreases expression |
EXP |
Fenofibrate results in decreased expression of APOB protein |
CTD |
PMID:21411093 |
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NCBI chr 2:21,001,429...21,044,073
Ensembl chr 2:21,001,429...21,044,073
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G |
APOC3 |
apolipoprotein C3 |
affects expression decreases expression |
ISO EXP |
Fenofibrate affects the expression of APOC3 mRNA Fenofibrate results in decreased expression of APOC3 mRNA; Fenofibrate results in decreased expression of APOC3 protein |
CTD |
PMID:8847480 PMID:10799317 PMID:20801182 PMID:24752549 |
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NCBI chr11:116,829,907...116,833,072
Ensembl chr11:116,829,706...116,833,072
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G |
APP |
amyloid beta precursor protein |
multiple interactions |
EXP |
Fenofibrate affects the reaction [PSEN1 protein affects the cleavage of APP protein] |
CTD |
PMID:17962197 |
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NCBI chr21:25,880,550...26,171,128
Ensembl chr21:25,880,535...26,171,128
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G |
AQP3 |
aquaporin 3 (Gill blood group) |
increases expression |
ISO |
Fenofibrate results in increased expression of AQP3 mRNA |
CTD |
PMID:32741897 |
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NCBI chr 9:33,441,160...33,447,593
Ensembl chr 9:33,441,156...33,447,596
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G |
AQP7 |
aquaporin 7 |
increases expression |
ISO |
Fenofibrate results in increased expression of AQP7 mRNA |
CTD |
PMID:32741897 |
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NCBI chr 9:33,383,191...33,402,568
Ensembl chr 9:33,383,179...33,402,682
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G |
AQP9 |
aquaporin 9 |
decreases expression |
EXP |
Fenofibrate results in decreased expression of AQP9 mRNA |
CTD |
PMID:25572481 |
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NCBI chr15:58,138,169...58,185,911
Ensembl chr15:58,138,169...58,185,911
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G |
ARFGEF2 |
ARF guanine nucleotide exchange factor 2 |
increases expression decreases expression |
EXP ISO |
Fenofibrate results in increased expression of ARFGEF2 mRNA Fenofibrate results in decreased expression of ARFGEF2 mRNA |
CTD |
PMID:25596134 |
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NCBI chr20:48,921,711...49,036,693
Ensembl chr20:48,921,711...49,036,693
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G |
ARHGEF10 |
Rho guanine nucleotide exchange factor 10 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of ARHGEF10 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 8:1,823,300...1,958,641
Ensembl chr 8:1,823,926...1,958,641
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G |
ARIH1 |
ariadne RBR E3 ubiquitin protein ligase 1 |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of ARIH1 mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of ARIH1 mRNA] |
CTD |
PMID:21318169 |
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NCBI chr15:72,474,330...72,602,987
Ensembl chr15:72,474,330...72,602,987
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G |
ARL1 |
ARF like GTPase 1 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of ARL1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr12:101,393,116...101,407,820
Ensembl chr12:101,393,116...101,407,772
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G |
ASB6 |
ankyrin repeat and SOCS box containing 6 |
multiple interactions increases expression |
ISO |
[PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of ASB6 mRNA Fenofibrate results in increased expression of ASB6 mRNA |
CTD |
PMID:21318169 |
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NCBI chr 9:129,634,605...129,642,151
Ensembl chr 9:129,634,604...129,642,169
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G |
ASNS |
asparagine synthetase (glutamine-hydrolyzing) |
increases expression |
ISO EXP |
Fenofibrate results in increased expression of ASNS mRNA |
CTD |
PMID:25596134 |
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NCBI chr 7:97,851,677...97,928,441
Ensembl chr 7:97,851,677...97,872,542
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G |
ATE1 |
arginyltransferase 1 |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of ATE1 mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of ATE1 mRNA] |
CTD |
PMID:21318169 |
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NCBI chr10:121,740,424...121,928,463
Ensembl chr10:121,709,393...121,928,801
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G |
ATF3 |
activating transcription factor 3 |
multiple interactions increases expression |
ISO EXP |
[Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of ATF3 mRNA Fenofibrate results in increased expression of ATF3 mRNA |
CTD |
PMID:18978307 PMID:25596134 |
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NCBI chr 1:212,565,407...212,620,777
Ensembl chr 1:212,565,334...212,620,777
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G |
ATF4 |
activating transcription factor 4 |
affects activity multiple interactions |
EXP ISO |
Fenofibrate affects the activity of ATF4 protein Fenofibrate inhibits the reaction [Dietary Fats results in increased expression of ATF4 mRNA]; Fenofibrate inhibits the reaction [Dietary Fats results in increased expression of ATF4 protein] |
CTD |
PMID:25596134 PMID:38216941 |
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NCBI chr22:39,520,559...39,522,686
Ensembl chr22:39,519,695...39,522,686
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G |
ATF6 |
activating transcription factor 6 |
multiple interactions |
ISO |
Fenofibrate inhibits the reaction [Dietary Fats results in increased expression of ATF6 mRNA]; Fenofibrate inhibits the reaction [Dietary Fats results in increased expression of ATF6 protein] |
CTD |
PMID:38216941 |
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NCBI chr 1:161,766,320...161,964,070
Ensembl chr 1:161,766,298...161,977,574
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G |
ATG12 |
autophagy related 12 |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of ATG12 mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of ATG12 mRNA] |
CTD |
PMID:21318169 |
|
NCBI chr 5:115,828,200...115,841,565
Ensembl chr 5:115,828,200...115,841,837
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G |
ATG7 |
autophagy related 7 |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of ATG7 mRNA Fenofibrate inhibits the reaction [tyloxapol results in decreased expression of ATG7 protein]; PPARA protein affects the reaction [Fenofibrate results in increased expression of ATG7 mRNA] |
CTD |
PMID:21318169 PMID:36905866 |
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NCBI chr 3:11,272,397...11,576,353
Ensembl chr 3:11,272,309...11,557,665
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G |
ATOSA |
atos homolog A |
decreases expression |
ISO |
Fenofibrate results in decreased expression of ATOSA mRNA |
CTD |
PMID:25596134 |
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NCBI chr15:52,581,321...52,709,815
Ensembl chr15:52,581,317...52,709,817
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G |
ATP2A2 |
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of ATP2A2 protein |
CTD |
PMID:20118634 |
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NCBI chr12:110,280,616...110,351,093
Ensembl chr12:110,280,756...110,351,093
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G |
ATP2B4 |
ATPase plasma membrane Ca2+ transporting 4 |
increases expression |
EXP |
Fenofibrate results in increased expression of ATP2B4 mRNA |
CTD |
PMID:25572481 |
|
NCBI chr 1:203,626,832...203,744,081
Ensembl chr 1:203,626,832...203,744,081
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G |
BAX |
BCL2 associated X, apoptosis regulator |
multiple interactions |
ISO |
Fenofibrate inhibits the reaction [tert-Butylhydroperoxide results in increased expression of BAX protein] |
CTD |
PMID:26989860 |
|
NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798
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G |
BCAR3 |
BCAR3 adaptor protein, NSP family member |
decreases expression |
ISO |
Fenofibrate results in decreased expression of BCAR3 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 1:93,561,741...93,848,151
Ensembl chr 1:93,561,741...93,847,150
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G |
BCAT1 |
branched chain amino acid transaminase 1 |
decreases expression |
EXP |
Fenofibrate results in decreased expression of BCAT1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr12:24,810,024...24,949,340
Ensembl chr12:24,810,024...24,949,101
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G |
BCAT2 |
branched chain amino acid transaminase 2 |
increases expression |
EXP |
Fenofibrate results in increased expression of BCAT2 mRNA |
CTD |
PMID:25596134 |
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NCBI chr19:48,795,064...48,811,029
Ensembl chr19:48,795,062...48,811,029
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G |
BCKDK |
branched chain keto acid dehydrogenase kinase |
decreases activity |
ISO |
Fenofibrate results in decreased activity of BCKDK protein |
CTD |
PMID:19819289 |
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NCBI chr16:31,108,386...31,117,640
Ensembl chr16:31,106,107...31,112,791
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G |
BCL2 |
BCL2 apoptosis regulator |
decreases expression multiple interactions |
EXP ISO |
Fenofibrate results in decreased expression of BCL2 mRNA Fenofibrate inhibits the reaction [tert-Butylhydroperoxide results in decreased expression of BCL2 protein] |
CTD |
PMID:15843896 PMID:26989860 |
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NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128
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G |
BCL2A1 |
BCL2 related protein A1 |
decreases expression |
EXP |
Fenofibrate results in decreased expression of BCL2A1 mRNA |
CTD |
PMID:20520642 |
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NCBI chr15:79,960,892...79,971,196
Ensembl chr15:79,960,892...79,971,196
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G |
BCL2L1 |
BCL2 like 1 |
decreases expression |
EXP |
Fenofibrate results in decreased expression of BCL2L1 mRNA |
CTD |
PMID:20520642 |
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NCBI chr20:31,664,452...31,723,963
Ensembl chr20:31,664,452...31,723,989
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G |
BCL3 |
BCL3 transcription coactivator |
decreases expression |
EXP |
Fenofibrate results in decreased expression of BCL3 mRNA |
CTD |
PMID:25596134 |
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NCBI chr19:44,747,705...44,760,044
Ensembl chr19:44,747,705...44,760,044
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G |
BCR |
BCR activator of RhoGEF and GTPase |
multiple interactions |
ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of BCR mRNA |
CTD |
PMID:18253720 |
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NCBI chr22:23,180,509...23,318,037
Ensembl chr22:23,179,704...23,318,037
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G |
BDH1 |
3-hydroxybutyrate dehydrogenase 1 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of BDH1 protein |
CTD |
PMID:20118634 |
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NCBI chr 3:197,509,783...197,573,343
Ensembl chr 3:197,509,783...197,573,323
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G |
BECN1 |
beclin 1 |
multiple interactions |
ISO |
Fenofibrate inhibits the reaction [tyloxapol results in decreased expression of BECN1 protein] |
CTD |
PMID:36905866 |
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NCBI chr17:42,810,132...42,824,282
Ensembl chr17:42,810,134...42,833,350
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G |
BHLHE40 |
basic helix-loop-helix family member e40 |
decreases expression |
EXP ISO |
Fenofibrate results in decreased expression of BHLHE40 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 3:4,979,437...4,985,323
Ensembl chr 3:4,979,437...4,985,323
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G |
BIRC3 |
baculoviral IAP repeat containing 3 |
decreases expression |
EXP |
Fenofibrate results in decreased expression of BIRC3 mRNA |
CTD |
PMID:20520642 |
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NCBI chr11:102,317,484...102,339,403
Ensembl chr11:102,317,484...102,339,403
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G |
BMF |
Bcl2 modifying factor |
increases expression decreases expression |
EXP ISO |
Fenofibrate results in increased expression of BMF mRNA Fenofibrate results in decreased expression of BMF mRNA |
CTD |
PMID:25572481 PMID:25596134 |
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NCBI chr15:40,087,890...40,108,879
Ensembl chr15:40,087,890...40,108,892
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G |
BNIP3 |
BCL2 interacting protein 3 |
increases expression |
ISO |
Fenofibrate results in increased expression of BNIP3 mRNA |
CTD |
PMID:25596134 |
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NCBI chr10:131,967,684...131,981,923
Ensembl chr10:131,967,684...131,981,967
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G |
BRAP |
BRCA1 associated protein |
affects expression multiple interactions |
ISO |
Fenofibrate affects the expression of BRAP mRNA PPARA protein affects the reaction [Fenofibrate affects the expression of BRAP mRNA] |
CTD |
PMID:21318169 |
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NCBI chr12:111,642,146...111,685,956
Ensembl chr12:111,642,146...111,685,956
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G |
BRCC3 |
BRCA1/BRCA2-containing complex subunit 3 |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of BRCC3 mRNA [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of BRCC3 mRNA |
CTD |
PMID:21318169 |
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NCBI chr X:155,071,508...155,123,077
Ensembl chr X:155,071,420...155,123,077
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G |
BRD2 |
bromodomain containing 2 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of BRD2 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 6:32,968,594...32,981,505
Ensembl chr 6:32,968,594...32,981,505
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G |
BTG2 |
BTG anti-proliferation factor 2 |
affects expression |
ISO |
Fenofibrate affects the expression of BTG2 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 1:203,305,519...203,309,602
Ensembl chr 1:203,305,491...203,309,602
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G |
C19orf12 |
chromosome 19 open reading frame 12 |
increases expression |
EXP |
Fenofibrate results in increased expression of C19ORF12 mRNA |
CTD |
PMID:25572481 |
|
NCBI chr19:29,698,886...29,715,789
Ensembl chr19:29,698,937...29,715,789
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G |
C9 |
complement C9 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of C9 mRNA |
CTD |
PMID:11798191 |
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NCBI chr 5:39,284,140...39,364,495
Ensembl chr 5:39,284,140...39,371,324
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G |
CA9 |
carbonic anhydrase 9 |
multiple interactions |
EXP |
Fenofibrate inhibits the reaction [Oxygen deficiency results in increased expression of CA9 mRNA]; Fenofibrate inhibits the reaction [Oxygen deficiency results in increased expression of CA9 protein] |
CTD |
PMID:34520103 |
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NCBI chr 9:35,673,928...35,681,159
Ensembl chr 9:35,673,928...35,681,159
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G |
CACNA2D3 |
calcium voltage-gated channel auxiliary subunit alpha2delta 3 |
increases expression |
ISO |
Fenofibrate results in increased expression of CACNA2D3 mRNA |
CTD |
PMID:32741897 |
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NCBI chr 3:54,122,552...55,074,557
Ensembl chr 3:54,122,552...55,074,557
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G |
CALM1 |
calmodulin 1 |
affects expression |
ISO |
Fenofibrate affects the expression of CALM1 mRNA |
CTD |
PMID:20801182 |
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NCBI chr14:90,396,502...90,408,268
Ensembl chr14:90,396,502...90,408,268
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G |
CANX |
calnexin |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of CANX mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of CANX mRNA] |
CTD |
PMID:21318169 |
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NCBI chr 5:179,678,656...179,731,641
Ensembl chr 5:179,678,628...179,731,641
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G |
CASP3 |
caspase 3 |
increases cleavage multiple interactions decreases expression |
EXP ISO |
Fenofibrate results in increased cleavage of CASP3 protein Fenofibrate inhibits the reaction [Cyclophosphamide results in increased cleavage of CASP3 protein] [ESR1 protein results in increased susceptibility to Estradiol] inhibits the reaction [Fenofibrate results in decreased expression of CASP3 protein]; Fenofibrate inhibits the reaction [[Fructose co-treated with Palmitic Acid] results in increased activity of CASP3 protein] [Fenofibrate co-treated with Pioglitazone] inhibits the reaction [Doxorubicin results in increased expression of CASP3 protein]; Fenofibrate inhibits the reaction [ACADS protein affects the cleavage of CASP3 protein]; Fenofibrate inhibits the reaction [Doxorubicin results in increased expression of CASP3 protein]; Fenofibrate inhibits the reaction [tert-Butylhydroperoxide results in increased cleavage of CASP3 protein] |
CTD |
PMID:20520642 PMID:26989860 PMID:29134746 PMID:32730863 PMID:36988379 PMID:38278497 More...
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NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062
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G |
CASP4 |
caspase 4 |
increases expression |
ISO |
Fenofibrate results in increased expression of CASP4 mRNA |
CTD |
PMID:17264098 |
|
NCBI chr11:104,942,866...104,968,574
Ensembl chr11:104,942,866...104,969,366
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G |
CAT |
catalase |
multiple interactions increases expression increases activity |
ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in increased activity of CAT protein; [Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of CAT mRNA Fenofibrate inhibits the reaction [Cyclophosphamide results in decreased activity of CAT protein] Fenofibrate results in increased expression of CAT mRNA Fenofibrate results in increased activity of CAT protein |
CTD |
PMID:17264098 PMID:18253720 PMID:38278497 |
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NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060
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CAV1 |
caveolin 1 |
increases expression |
EXP |
Fenofibrate results in increased expression of CAV1 mRNA |
CTD |
PMID:15314095 |
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NCBI chr 7:116,525,009...116,561,185
Ensembl chr 7:116,524,994...116,561,179
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CBLB |
Cbl proto-oncogene B |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of CBLB mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of CBLB mRNA] |
CTD |
PMID:21318169 |
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NCBI chr 3:105,655,461...105,869,449
Ensembl chr 3:105,655,461...105,869,552
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CCDC34 |
coiled-coil domain containing 34 |
increases expression |
ISO |
Fenofibrate results in increased expression of CCDC34 mRNA |
CTD |
PMID:32741897 |
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NCBI chr11:27,338,512...27,363,215
Ensembl chr11:27,330,827...27,363,234
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CCDC90B |
coiled-coil domain containing 90B |
increases expression |
ISO |
Fenofibrate results in increased expression of CCDC90B mRNA |
CTD |
PMID:25596134 |
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NCBI chr11:83,259,081...83,286,367
Ensembl chr11:83,259,081...83,286,390
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G |
CCL13 |
C-C motif chemokine ligand 13 |
increases expression |
EXP |
Fenofibrate results in increased expression of CCL13 mRNA |
CTD |
PMID:25572481 |
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NCBI chr17:34,356,480...34,358,610
Ensembl chr17:34,356,480...34,358,610
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G |
CCL2 |
C-C motif chemokine ligand 2 |
multiple interactions decreases expression |
EXP ISO |
Fenofibrate inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein]; Fenofibrate inhibits the reaction [Glucose results in increased expression of CCL2 mRNA]; Fenofibrate inhibits the reaction [Glucose results in increased expression of CCL2 protein]; Fenofibrate inhibits the reaction [Glucose results in increased secretion of CCL2 protein] Fenofibrate results in decreased expression of CCL2 mRNA; Fenofibrate results in decreased expression of CCL2 protein Fenofibrate inhibits the reaction [Lipopolysaccharides results in increased expression of CCL2 mRNA]; Fenofibrate inhibits the reaction [Lipopolysaccharides results in increased secretion of CCL2 protein] |
CTD |
PMID:15968640 PMID:16306350 PMID:16600694 PMID:18356826 PMID:19132243 PMID:32613381 More...
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NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208
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G |
CCL5 |
C-C motif chemokine ligand 5 |
multiple interactions |
EXP |
Fenofibrate inhibits the reaction [Chenodeoxycholic Acid results in increased expression of CCL5 mRNA]; Fenofibrate inhibits the reaction [Chenodeoxycholic Acid results in increased expression of CCL5 protein]; Fenofibrate inhibits the reaction [TNF protein results in increased expression of CCL5 mRNA]; Fenofibrate inhibits the reaction [TNF protein results in increased expression of CCL5 protein] |
CTD |
PMID:12126966 PMID:12586603 |
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NCBI chr17:35,871,491...35,880,360
Ensembl chr17:35,871,491...35,880,793
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G |
CCN1 |
cellular communication network factor 1 |
decreases expression |
EXP |
Fenofibrate results in decreased expression of CCN1 mRNA |
CTD |
PMID:25572481 |
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NCBI chr 1:85,580,761...85,583,950
Ensembl chr 1:85,580,761...85,584,589
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G |
CCND1 |
cyclin D1 |
decreases expression multiple interactions increases expression |
EXP ISO |
Fenofibrate results in decreased expression of CCND1 mRNA; Fenofibrate results in decreased expression of CCND1 protein ESR1 protein inhibits the reaction [Fenofibrate results in increased expression of CCND1 protein]; Estradiol inhibits the reaction [Fenofibrate results in increased expression of CCND1 protein] Fenofibrate results in increased expression of CCND1 mRNA [Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of CCND1 mRNA |
CTD |
PMID:16569247 PMID:17264098 PMID:18253720 PMID:18978307 PMID:20520642 PMID:29134746 More...
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NCBI chr11:69,641,156...69,654,474
Ensembl chr11:69,641,156...69,654,474
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G |
CCNF |
cyclin F |
increases expression |
ISO |
Fenofibrate results in increased expression of CCNF mRNA |
CTD |
PMID:32741897 |
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NCBI chr16:2,429,447...2,458,854
Ensembl chr16:2,429,394...2,458,854
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G |
CCNG2 |
cyclin G2 |
decreases expression increases expression |
EXP ISO |
Fenofibrate results in decreased expression of CCNG2 mRNA Fenofibrate results in increased expression of CCNG2 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 4:77,157,207...77,170,060
Ensembl chr 4:77,157,207...77,433,388
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G |
CCNT1 |
cyclin T1 |
multiple interactions |
ISO |
Fenofibrate affects the reaction [[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CCNT1 mRNA]; Fenofibrate affects the reaction [[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CCNT1 protein] |
CTD |
PMID:20828602 |
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NCBI chr12:48,688,458...48,716,707
Ensembl chr12:48,688,458...48,716,998
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CD14 |
CD14 molecule |
increases expression |
EXP |
Fenofibrate results in increased expression of CD14 mRNA |
CTD |
PMID:25572481 |
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NCBI chr 5:140,631,732...140,633,701
Ensembl chr 5:140,631,728...140,633,700
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G |
CD36 |
CD36 molecule (CD36 blood group) |
increases expression multiple interactions |
ISO EXP |
Fenofibrate results in increased expression of CD36 mRNA Fenofibrate inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of CD36 mRNA] |
CTD |
PMID:16707586 PMID:17118139 PMID:25572481 PMID:32613381 |
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NCBI chr 7:80,602,207...80,679,274
Ensembl chr 7:80,369,575...80,679,277
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CD40 |
CD40 molecule |
decreases expression |
EXP |
Fenofibrate results in decreased expression of CD40 mRNA |
CTD |
PMID:20520642 |
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NCBI chr20:46,118,314...46,129,858
Ensembl chr20:46,118,271...46,129,863
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G |
CD40LG |
CD40 ligand |
multiple interactions decreases expression |
EXP |
candesartan promotes the reaction [Fenofibrate results in decreased expression of CD40LG protein]; Fenofibrate promotes the reaction [candesartan results in decreased expression of CD40LG protein] |
CTD |
PMID:16443859 |
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NCBI chr X:136,648,158...136,660,390
Ensembl chr X:136,648,158...136,660,390
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G |
CDC25A |
cell division cycle 25A |
increases expression |
ISO |
Fenofibrate results in increased expression of CDC25A mRNA |
CTD |
PMID:17264098 |
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NCBI chr 3:48,157,146...48,188,417
Ensembl chr 3:48,157,146...48,188,417
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G |
CDK20 |
cyclin dependent kinase 20 |
increases expression |
EXP |
Fenofibrate results in increased expression of CDK20 mRNA |
CTD |
PMID:25572481 |
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NCBI chr 9:87,966,441...87,974,533
Ensembl chr 9:87,966,441...87,974,753
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G |
CDK9 |
cyclin dependent kinase 9 |
multiple interactions |
ISO |
Fenofibrate affects the reaction [[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CDK9 mRNA]; Fenofibrate affects the reaction [[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CDK9 protein] |
CTD |
PMID:20828602 |
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NCBI chr 9:127,786,034...127,790,792
Ensembl chr 9:127,785,679...127,790,792
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G |
CDKN1A |
cyclin dependent kinase inhibitor 1A |
multiple interactions decreases expression |
ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of CDKN1A mRNA Fenofibrate results in decreased expression of CDKN1A mRNA |
CTD |
PMID:18253720 PMID:25596134 |
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NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,397
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G |
CDKN1B |
cyclin dependent kinase inhibitor 1B |
multiple interactions decreases expression |
ISO EXP |
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of CDKN1B mRNA ESR1 protein inhibits the reaction [Fenofibrate results in decreased expression of CDKN1B protein]; Estradiol inhibits the reaction [Fenofibrate results in decreased expression of CDKN1B protein] |
CTD |
PMID:18253720 PMID:29134746 |
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NCBI chr12:12,717,368...12,722,369
Ensembl chr12:12,685,498...12,722,369
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G |
CEP128 |
centrosomal protein 128 |
increases expression |
ISO |
Fenofibrate results in increased expression of CEP128 mRNA |
CTD |
PMID:32741897 |
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NCBI chr14:80,476,969...80,959,502
Ensembl chr14:80,476,983...80,959,517
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G |
CERS5 |
ceramide synthase 5 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of CERS5 mRNA |
CTD |
PMID:25596134 |
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NCBI chr12:50,129,289...50,167,369
Ensembl chr12:50,129,289...50,167,533
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G |
CES1 |
carboxylesterase 1 |
multiple interactions |
ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of CES1 mRNA |
CTD |
PMID:18253720 |
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NCBI chr16:55,802,851...55,833,096
Ensembl chr16:55,802,851...55,833,337
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G |
CHEK1 |
checkpoint kinase 1 |
increases expression |
ISO |
Fenofibrate results in increased expression of CHEK1 mRNA |
CTD |
PMID:17264098 |
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NCBI chr11:125,625,136...125,681,124
Ensembl chr11:125,625,163...125,676,255
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G |
CHEK2 |
checkpoint kinase 2 |
multiple interactions |
ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of CHEK2 mRNA |
CTD |
PMID:18253720 |
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NCBI chr22:28,687,743...28,741,834
Ensembl chr22:28,687,743...28,742,422
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G |
CHID1 |
chitinase domain containing 1 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of CHID1 mRNA |
CTD |
PMID:11798191 |
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NCBI chr11:867,859...915,214
Ensembl chr11:867,859...915,058
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G |
CHRNA2 |
cholinergic receptor nicotinic alpha 2 subunit |
increases expression |
ISO |
Fenofibrate results in increased expression of CHRNA2 mRNA |
CTD |
PMID:32741897 |
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NCBI chr 8:27,459,756...27,479,261
Ensembl chr 8:27,459,756...27,479,883
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G |
CHST8 |
carbohydrate sulfotransferase 8 |
multiple interactions |
ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of CHST8 mRNA |
CTD |
PMID:18253720 |
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NCBI chr19:33,621,953...33,773,509
Ensembl chr19:33,621,953...33,773,509
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G |
CISH |
cytokine inducible SH2 containing protein |
decreases expression multiple interactions |
ISO |
Fenofibrate results in decreased expression of CISH mRNA PPARA protein affects the reaction [Fenofibrate results in decreased expression of CISH mRNA] |
CTD |
PMID:21318169 |
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NCBI chr 3:50,606,489...50,611,774
Ensembl chr 3:50,606,489...50,611,774
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G |
CMBL |
carboxymethylenebutenolidase homolog |
increases expression |
ISO |
Fenofibrate results in increased expression of CMBL mRNA |
CTD |
PMID:25596134 |
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NCBI chr 5:10,277,595...10,307,902
Ensembl chr 5:10,275,875...10,307,902
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G |
CNOT4 |
CCR4-NOT transcription complex subunit 4 |
multiple interactions increases expression |
ISO |
PPARA protein affects the reaction [Fenofibrate results in increased expression of CNOT4 mRNA] |
CTD |
PMID:21318169 |
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NCBI chr 7:135,361,795...135,510,102
Ensembl chr 7:135,361,795...135,510,145
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G |
COL1A1 |
collagen type I alpha 1 chain |
multiple interactions |
EXP ISO |
Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]] Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of COL1A1 mRNA]; Fenofibrate inhibits the reaction [AHR protein affects the reaction [AGT protein results in increased expression of COL1A1 mRNA]]; Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]; Fenofibrate inhibits the reaction [Zoledronic Acid results in increased expression of COL1A1 mRNA]; NR0B2 protein inhibits the reaction [Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of COL1A1 mRNA]] |
CTD |
PMID:19593819 PMID:28871336 PMID:31016362 |
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NCBI chr17:50,184,101...50,201,631
Ensembl chr17:50,184,101...50,201,632
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G |
COL3A1 |
collagen type III alpha 1 chain |
multiple interactions |
ISO |
Fenofibrate inhibits the reaction [AHR protein affects the reaction [AGT protein results in increased expression of COL3A1 mRNA]]; Fenofibrate inhibits the reaction [Zoledronic Acid results in increased expression of COL3A1 mRNA] |
CTD |
PMID:28871336 PMID:31016362 |
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NCBI chr 2:188,974,373...189,012,746
Ensembl chr 2:188,974,373...189,012,746
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G |
COL4A1 |
collagen type IV alpha 1 chain |
multiple interactions |
ISO |
Fenofibrate inhibits the reaction [zoledronic acid results in increased expression of COL4A1 mRNA] |
CTD |
PMID:28871336 |
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NCBI chr13:110,148,963...110,307,157
Ensembl chr13:110,148,963...110,307,202
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G |
COLQ |
collagen like tail subunit of asymmetric acetylcholinesterase |
increases expression |
ISO |
Fenofibrate results in increased expression of COLQ mRNA |
CTD |
PMID:27665778 PMID:32741897 |
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NCBI chr 3:15,450,133...15,521,706
Ensembl chr 3:15,450,133...15,521,751
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G |
COQ7 |
coenzyme Q7, hydroxylase |
increases expression |
ISO |
Fenofibrate results in increased expression of COQ7 mRNA |
CTD |
PMID:16595124 |
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NCBI chr16:19,067,614...19,083,097
Ensembl chr16:19,067,614...19,080,095
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G |
COX6B2 |
cytochrome c oxidase subunit 6B2 |
increases expression |
ISO |
Fenofibrate results in increased expression of COX6B2 mRNA |
CTD |
PMID:11798191 |
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NCBI chr19:55,349,704...55,354,719
Ensembl chr19:55,349,306...55,354,719
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G |
CPT1A |
carnitine palmitoyltransferase 1A |
increases expression multiple interactions |
ISO EXP |
Fenofibrate results in increased expression of CPT1A mRNA Fenofibrate inhibits the reaction [zoledronic acid results in decreased expression of CPT1A mRNA] Fenofibrate affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA]; Fenofibrate inhibits the reaction [Fatty Acids, Nonesterified results in decreased expression of CPT1A protein]; Fenofibrate promotes the reaction [Fatty Acids, Nonesterified results in increased expression of CPT1A mRNA]; Fenofibrate promotes the reaction [Oleic Acid results in increased expression of CPT1A mRNA] |
CTD |
PMID:16595124 PMID:17070643 PMID:17118139 PMID:19124612 PMID:24534255 PMID:24735863 PMID:25572481 PMID:27665778 PMID:28871336 PMID:30611848 PMID:32613381 PMID:32741897 More...
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NCBI chr11:68,754,620...68,844,277
Ensembl chr11:68,754,620...68,844,410
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G |
CPT1B |
carnitine palmitoyltransferase 1B |
affects expression multiple interactions increases expression |
ISO |
Fenofibrate affects the expression of CPT1B mRNA Fenofibrate inhibits the reaction [Pyrazinamide results in decreased expression of CPT1B mRNA] Fenofibrate results in increased expression of CPT1B mRNA |
CTD |
PMID:16595124 PMID:19395589 PMID:20801182 PMID:27071702 PMID:32741897 |
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NCBI chr22:50,568,861...50,578,612
Ensembl chr22:50,568,861...50,578,465
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G |
CPT2 |
carnitine palmitoyltransferase 2 |
decreases expression multiple interactions increases expression |
ISO EXP |
Fenofibrate results in decreased expression of CPT2 protein Fenofibrate inhibits the reaction [zoledronic acid results in decreased expression of CPT2 mRNA] Fenofibrate results in increased expression of CPT2 mRNA [Oleic Acid co-treated with Fenofibrate] results in increased expression of CPT2 mRNA |
CTD |
PMID:16595124 PMID:16707586 PMID:19395589 PMID:20118634 PMID:24534255 PMID:25572481 PMID:27665778 PMID:28871336 PMID:32741897 More...
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NCBI chr 1:53,196,824...53,214,197
Ensembl chr 1:53,196,792...53,214,197
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CRAT |
carnitine O-acetyltransferase |
increases expression increases activity multiple interactions |
ISO |
Fenofibrate results in increased expression of CRAT mRNA Fenofibrate results in increased activity of CRAT protein [Fenofibrate co-treated with Diethylnitrosamine] results in increased activity of CRAT protein; [Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of CRAT mRNA |
CTD |
PMID:11798191 PMID:17264098 PMID:18253720 PMID:27665778 PMID:32741897 |
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NCBI chr 9:129,094,794...129,110,793
Ensembl chr 9:129,094,142...129,111,189
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CREB3L3 |
cAMP responsive element binding protein 3 like 3 |
increases expression |
EXP ISO |
Fenofibrate results in increased expression of CREB3L3 mRNA |
CTD |
PMID:25572481 PMID:32741897 |
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NCBI chr19:4,153,631...4,173,054
Ensembl chr19:4,153,631...4,173,054
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G |
CROT |
carnitine O-octanoyltransferase |
increases expression |
ISO |
Fenofibrate results in increased expression of CROT mRNA |
CTD |
PMID:32741897 |
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NCBI chr 7:87,345,664...87,399,794
Ensembl chr 7:87,345,664...87,399,794
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CRP |
C-reactive protein |
multiple interactions decreases expression |
EXP |
candesartan promotes the reaction [Fenofibrate results in decreased expression of CRP protein]; Fenofibrate promotes the reaction [candesartan results in decreased expression of CRP protein] |
CTD |
PMID:16123850 PMID:16443859 |
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NCBI chr 1:159,712,289...159,714,589
Ensembl chr 1:159,712,289...159,714,589
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G |
CSF1R |
colony stimulating factor 1 receptor |
decreases expression |
ISO |
Fenofibrate results in decreased expression of CSF1R mRNA |
CTD |
PMID:16707586 |
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NCBI chr 5:150,053,295...150,113,365
Ensembl chr 5:150,053,291...150,113,372
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G |
CSF2 |
colony stimulating factor 2 |
multiple interactions |
ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of CSF2 mRNA |
CTD |
PMID:18253720 |
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NCBI chr 5:132,073,789...132,076,170
Ensembl chr 5:132,073,789...132,076,170
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G |
CTH |
cystathionine gamma-lyase |
increases expression decreases expression |
EXP ISO |
Fenofibrate results in increased expression of CTH mRNA Fenofibrate results in decreased expression of CTH mRNA |
CTD |
PMID:25596134 |
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NCBI chr 1:70,411,268...70,439,851
Ensembl chr 1:70,411,218...70,439,851
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G |
CTSC |
cathepsin C |
decreases expression |
ISO |
Fenofibrate results in decreased expression of CTSC mRNA |
CTD |
PMID:25596134 |
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NCBI chr11:88,293,592...88,337,736
Ensembl chr11:88,265,069...88,359,684
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G |
CX3CL1 |
C-X3-C motif chemokine ligand 1 |
multiple interactions |
EXP |
Fenofibrate inhibits the reaction [Glucose results in increased expression of CX3CL1 mRNA]; Fenofibrate inhibits the reaction [Glucose results in increased expression of CX3CL1 protein] |
CTD |
PMID:19132243 |
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NCBI chr16:57,372,490...57,385,044
Ensembl chr16:57,372,477...57,385,044
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G |
CYCS |
cytochrome c, somatic |
multiple interactions |
EXP |
Fenofibrate inhibits the reaction [[Fructose co-treated with Palmitic Acid] results in increased expression of CYCS protein] |
CTD |
PMID:32730863 |
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NCBI chr 7:25,118,656...25,125,260
Ensembl chr 7:25,118,656...25,125,260
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G |
CYLD |
CYLD lysine 63 deubiquitinase |
decreases expression multiple interactions |
ISO |
Fenofibrate results in decreased expression of CYLD mRNA PPARA protein affects the reaction [Fenofibrate results in decreased expression of CYLD mRNA] |
CTD |
PMID:21318169 |
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NCBI chr16:50,742,086...50,801,935
Ensembl chr16:50,742,050...50,801,935
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G |
CYP1A1 |
cytochrome P450 family 1 subfamily A member 1 |
increases expression decreases activity |
ISO EXP |
Fenofibrate results in increased expression of CYP1A1 mRNA Fenofibrate results in decreased activity of CYP1A1 protein |
CTD |
PMID:19118567 PMID:33814510 |
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NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536
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G |
CYP1A2 |
cytochrome P450 family 1 subfamily A member 2 |
multiple interactions affects expression |
ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of CYP1A2 mRNA Fenofibrate affects the expression of CYP1A2 mRNA |
CTD |
PMID:18253720 PMID:20801182 PMID:25596134 |
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NCBI chr15:74,748,845...74,756,607
Ensembl chr15:74,748,845...74,756,607
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G |
CYP1B1 |
cytochrome P450 family 1 subfamily B member 1 |
decreases activity |
EXP |
Fenofibrate results in decreased activity of CYP1B1 protein |
CTD |
PMID:33814510 |
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NCBI chr 2:38,067,509...38,076,151
Ensembl chr 2:38,066,973...38,109,902
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G |
CYP2A7 |
cytochrome P450 family 2 subfamily A member 7 |
multiple interactions |
ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of CYP2A3 mRNA |
CTD |
PMID:18253720 |
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NCBI chr19:40,875,439...40,882,231
Ensembl chr19:40,875,439...40,882,752
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G |
CYP2B6 |
cytochrome P450 family 2 subfamily B member 6 |
increases expression |
ISO |
Fenofibrate results in increased expression of CYP2B10 mRNA |
CTD |
PMID:11798191 |
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NCBI chr19:40,991,282...41,018,398
Ensembl chr19:40,991,282...41,018,398
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G |
CYP2C18 |
cytochrome P450 family 2 subfamily C member 18 |
multiple interactions |
ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of CYP2C mRNA |
CTD |
PMID:18253720 |
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NCBI chr10:94,683,729...94,736,190
Ensembl chr10:94,683,729...94,736,190
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CYP2C19 |
cytochrome P450 family 2 subfamily C member 19 |
increases expression |
EXP |
Fenofibrate results in increased expression of CYP2C19 mRNA |
CTD |
PMID:25572481 |
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NCBI chr10:94,762,681...94,855,547
Ensembl chr10:94,762,681...94,855,547
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CYP2C8 |
cytochrome P450 family 2 subfamily C member 8 |
decreases activity affects expression increases expression |
EXP |
Fenofibrate results in decreased activity of CYP2C8 protein Fenofibrate affects the expression of CYP2C8 protein Fenofibrate results in increased expression of CYP2C8 mRNA |
CTD |
PMID:15601807 PMID:25572481 PMID:29960002 |
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NCBI chr10:95,036,772...95,069,497
Ensembl chr10:95,036,772...95,069,497
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CYP2D6 |
cytochrome P450 family 2 subfamily D member 6 (gene/pseudogene) |
multiple interactions |
ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of CYP2D22 mRNA |
CTD |
PMID:18253720 |
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NCBI chr22:42,126,499...42,130,810
Ensembl chr22:42,126,499...42,130,865
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CYP2E1 |
cytochrome P450 family 2 subfamily E member 1 |
increases expression |
ISO |
Fenofibrate results in increased expression of CYP2E1 mRNA |
CTD |
PMID:19118567 |
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NCBI chr10:133,527,363...133,539,123
Ensembl chr10:133,520,406...133,561,220
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CYP2F1 |
cytochrome P450 family 2 subfamily F member 1 |
multiple interactions |
ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of CYP2F2 mRNA |
CTD |
PMID:18253720 |
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NCBI chr19:41,114,432...41,128,381
Ensembl chr19:41,114,432...41,128,381
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CYP2J2 |
cytochrome P450 family 2 subfamily J member 2 |
affects expression |
EXP |
Fenofibrate affects the expression of CYP2J2 protein |
CTD |
PMID:29960002 |
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NCBI chr 1:59,893,308...59,969,212
Ensembl chr 1:59,893,308...59,926,773
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CYP3A5 |
cytochrome P450 family 3 subfamily A member 5 |
multiple interactions |
ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of CYP3A13 mRNA |
CTD |
PMID:18253720 |
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NCBI chr 7:99,648,194...99,679,996
Ensembl chr 7:99,648,194...99,679,996
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CYP3A7 |
cytochrome P450 family 3 subfamily A member 7 |
increases expression |
EXP |
Fenofibrate results in increased expression of CYP3A7 mRNA |
CTD |
PMID:19118567 |
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NCBI chr 7:99,705,036...99,735,196
Ensembl chr 7:99,705,036...99,735,196
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CYP4A11 |
cytochrome P450 family 4 subfamily A member 11 |
increases expression |
EXP |
Fenofibrate results in increased expression of CYP4A11 mRNA |
CTD |
PMID:25572481 |
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NCBI chr 1:46,929,188...46,941,476
Ensembl chr 1:46,929,177...46,941,484
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CYP4A22 |
cytochrome P450 family 4 subfamily A member 22 |
increases expression multiple interactions affects expression |
EXP ISO |
Fenofibrate results in increased expression of CYP4A22 mRNA Fenofibrate results in increased expression of CYP4A1 mRNA [Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of CYP4A1 mRNA Fenofibrate affects the expression of CYP4A1 mRNA |
CTD |
PMID:17264098 PMID:18775883 PMID:20801182 PMID:25572481 PMID:27665778 PMID:32741897 More...
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NCBI chr 1:47,137,441...47,149,727
Ensembl chr 1:47,137,435...47,149,727
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CYP4B1 |
cytochrome P450 family 4 subfamily B member 1 |
multiple interactions |
ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of CYP4B1 mRNA |
CTD |
PMID:18253720 |
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NCBI chr 1:46,799,046...46,819,413
Ensembl chr 1:46,757,838...46,819,413
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CYP4X1 |
cytochrome P450 family 4 subfamily X member 1 |
increases expression |
EXP |
Fenofibrate results in increased expression of CYP4X1 mRNA |
CTD |
PMID:25572481 |
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NCBI chr 1:46,961,364...47,055,432
Ensembl chr 1:47,023,669...47,050,751
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CYP7A1 |
cytochrome P450 family 7 subfamily A member 1 |
multiple interactions decreases expression |
ISO EXP |
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of CYP7A1 mRNA Fenofibrate results in decreased expression of CYP7A1 mRNA |
CTD |
PMID:14685799 PMID:18253720 |
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NCBI chr 8:58,490,178...58,500,163
Ensembl chr 8:58,490,178...58,500,163
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CYP7B1 |
cytochrome P450 family 7 subfamily B member 1 |
multiple interactions |
ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of CYP7B1 mRNA |
CTD |
PMID:18253720 |
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NCBI chr 8:64,586,575...64,798,737
Ensembl chr 8:64,587,763...64,798,737
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CYP8B1 |
cytochrome P450 family 8 subfamily B member 1 |
multiple interactions increases expression |
ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of CYP8B1 mRNA Fenofibrate results in increased expression of CYP8B1 mRNA |
CTD |
PMID:18253720 PMID:32741897 |
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NCBI chr 3:42,872,192...42,875,879
Ensembl chr 3:42,856,005...42,875,898
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DACT2 |
dishevelled binding antagonist of beta catenin 2 |
increases expression |
ISO |
Fenofibrate results in increased expression of DACT2 mRNA |
CTD |
PMID:27665778 |
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NCBI chr 6:168,292,830...168,319,777
Ensembl chr 6:168,292,830...168,319,777
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DBI |
diazepam binding inhibitor, acyl-CoA binding protein |
increases expression |
ISO |
Fenofibrate results in increased expression of DBI mRNA |
CTD |
PMID:17118139 |
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NCBI chr 2:119,366,977...119,372,543
Ensembl chr 2:119,366,924...119,372,550
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DCUN1D1 |
defective in cullin neddylation 1 domain containing 1 |
increases expression |
ISO |
Fenofibrate results in increased expression of DCUN1D1 mRNA |
CTD |
PMID:21318169 |
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NCBI chr 3:182,938,074...182,985,918
Ensembl chr 3:182,938,074...182,985,953
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DDIT3 |
DNA damage inducible transcript 3 |
increases expression |
EXP |
Fenofibrate results in increased expression of DDIT3 mRNA |
CTD |
PMID:25596134 |
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NCBI chr12:57,516,588...57,520,517
Ensembl chr12:57,516,588...57,521,737
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DDIT4 |
DNA damage inducible transcript 4 |
decreases expression increases expression |
EXP ISO |
Fenofibrate results in decreased expression of DDIT4 mRNA Fenofibrate results in increased expression of DDIT4 mRNA |
CTD |
PMID:25596134 |
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NCBI chr10:72,273,924...72,276,036
Ensembl chr10:72,273,919...72,276,036
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DDX24 |
DEAD-box helicase 24 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of DDX24 mRNA |
CTD |
PMID:25596134 |
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NCBI chr14:94,048,287...94,081,202
Ensembl chr14:94,048,287...94,081,202
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DECR1 |
2,4-dienoyl-CoA reductase 1 |
increases expression affects expression |
ISO |
Fenofibrate results in increased expression of DECR1 mRNA Fenofibrate results in increased expression of DECR1 mRNA; Fenofibrate results in increased expression of DECR1 protein Fenofibrate affects the expression of DECR1 mRNA |
CTD |
PMID:11798191 PMID:20118634 PMID:20801182 PMID:27665778 PMID:32741897 |
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NCBI chr 8:90,001,477...90,053,633
Ensembl chr 8:90,001,405...90,053,633
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DECR2 |
2,4-dienoyl-CoA reductase 2 |
increases expression |
ISO |
Fenofibrate results in increased expression of DECR2 mRNA |
CTD |
PMID:27665778 |
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NCBI chr16:401,885...412,482
Ensembl chr16:401,858...412,487
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DHX37 |
DEAH-box helicase 37 |
increases expression |
EXP |
Fenofibrate results in increased expression of DHX37 mRNA |
CTD |
PMID:25596134 |
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NCBI chr12:124,946,826...124,989,131
Ensembl chr12:124,946,825...124,989,131
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DMD |
dystrophin |
decreases expression |
ISO |
Fenofibrate results in decreased expression of DMD mRNA |
CTD |
PMID:11798191 |
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NCBI chr X:31,119,222...33,339,388
Ensembl chr X:31,097,677...33,339,609
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DNAJA2 |
DnaJ heat shock protein family (Hsp40) member A2 |
multiple interactions increases expression |
ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of DNAJA2 mRNA Fenofibrate results in increased expression of DNAJA2 mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of DNAJA2 mRNA] |
CTD |
PMID:18253720 PMID:21318169 |
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NCBI chr16:46,955,362...46,973,674
Ensembl chr16:46,955,362...46,973,674
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DNAJA3 |
DnaJ heat shock protein family (Hsp40) member A3 |
increases expression |
ISO |
Fenofibrate results in increased expression of DNAJA3 mRNA |
CTD |
PMID:21318169 |
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NCBI chr16:4,425,868...4,456,775
Ensembl chr16:4,425,805...4,456,775
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DNAJB1 |
DnaJ heat shock protein family (Hsp40) member B1 |
multiple interactions |
ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of DNAJB1 mRNA |
CTD |
PMID:18253720 |
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NCBI chr19:14,514,769...14,560,391
Ensembl chr19:14,513,789...14,560,391
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DNAJB4 |
DnaJ heat shock protein family (Hsp40) member B4 |
decreases expression multiple interactions |
ISO |
Fenofibrate results in decreased expression of DNAJB4 mRNA PPARA protein affects the reaction [Fenofibrate results in decreased expression of DNAJB4 mRNA] |
CTD |
PMID:21318169 |
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NCBI chr 1:77,979,175...78,017,964
Ensembl chr 1:77,979,175...78,017,964
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DNAJB6 |
DnaJ heat shock protein family (Hsp40) member B6 |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of DNAJB6 mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of DNAJB6 mRNA] |
CTD |
PMID:21318169 |
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NCBI chr 7:157,337,004...157,417,439
Ensembl chr 7:157,335,381...157,417,439
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DNAJB9 |
DnaJ heat shock protein family (Hsp40) member B9 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of DNAJB9 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 7:108,569,874...108,574,850
Ensembl chr 7:108,569,867...108,574,850
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DNAJC14 |
DnaJ heat shock protein family (Hsp40) member C14 |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of DNAJC14 mRNA [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of DNAJC14 mRNA |
CTD |
PMID:21318169 |
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NCBI chr12:55,820,985...55,830,775
Ensembl chr12:55,820,960...55,830,824
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DNAJC19 |
DnaJ heat shock protein family (Hsp40) member C19 |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of DNAJC19 mRNA [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of DNAJC19 mRNA |
CTD |
PMID:21318169 |
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NCBI chr 3:180,983,709...180,989,838
Ensembl chr 3:180,983,697...180,989,774
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DNAJC2 |
DnaJ heat shock protein family (Hsp40) member C2 |
multiple interactions increases expression |
ISO |
[PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of DNAJC2 mRNA Fenofibrate results in increased expression of DNAJC2 mRNA |
CTD |
PMID:21318169 |
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NCBI chr 7:103,312,289...103,344,767
Ensembl chr 7:103,312,289...103,344,830
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DNAJC27 |
DnaJ heat shock protein family (Hsp40) member C27 |
decreases expression multiple interactions |
ISO |
Fenofibrate results in decreased expression of RBJ mRNA PPARA protein affects the reaction [Fenofibrate results in decreased expression of RBJ mRNA] |
CTD |
PMID:21318169 |
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NCBI chr 2:24,943,636...24,972,094
Ensembl chr 2:24,943,636...24,972,094
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DNAJC3 |
DnaJ heat shock protein family (Hsp40) member C3 |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of DNAJC3 mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of DNAJC3 mRNA] |
CTD |
PMID:21318169 |
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NCBI chr13:95,677,139...95,794,988
Ensembl chr13:95,677,139...95,794,988
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DNAJC5 |
DnaJ heat shock protein family (Hsp40) member C5 |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of DNAJC5 mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of DNAJC5 mRNA] |
CTD |
PMID:21318169 |
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NCBI chr20:63,895,126...63,936,011
Ensembl chr20:63,895,126...63,936,031
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DNAJC5B |
DnaJ heat shock protein family (Hsp40) member C5 beta |
increases expression |
ISO |
Fenofibrate results in increased expression of DNAJC5B mRNA |
CTD |
PMID:25596134 |
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NCBI chr 8:66,014,978...66,101,245
Ensembl chr 8:66,021,553...66,101,245
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DNM1L |
dynamin 1 like |
multiple interactions |
EXP |
Fenofibrate inhibits the reaction [[Fructose co-treated with Palmitic Acid] results in increased expression of DNM1L protein] |
CTD |
PMID:32730863 |
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NCBI chr12:32,679,301...32,745,650
Ensembl chr12:32,679,200...32,745,650
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DNMBP |
dynamin binding protein |
decreases expression |
ISO |
Fenofibrate results in decreased expression of DNMBP mRNA |
CTD |
PMID:25596134 |
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NCBI chr10:99,875,571...100,009,947
Ensembl chr10:99,875,577...100,009,947
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DUSP5 |
dual specificity phosphatase 5 |
increases expression |
EXP |
Fenofibrate results in increased expression of DUSP5 mRNA |
CTD |
PMID:25596134 |
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NCBI chr10:110,497,907...110,511,533
Ensembl chr10:110,497,907...110,511,533
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ECH1 |
enoyl-CoA hydratase 1 |
affects expression increases expression |
ISO |
Fenofibrate affects the expression of ECH1 mRNA Fenofibrate results in increased expression of ECH1 mRNA; Fenofibrate results in increased expression of ECH1 protein |
CTD |
PMID:11798191 PMID:17118139 PMID:20118634 PMID:20801182 PMID:27665778 PMID:32741897 More...
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NCBI chr19:38,815,422...38,831,794
Ensembl chr19:38,815,422...38,831,841
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ECHS1 |
enoyl-CoA hydratase, short chain 1 |
increases expression |
EXP |
Fenofibrate results in increased expression of ECHS1 mRNA |
CTD |
PMID:24752549 |
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NCBI chr10:133,362,485...133,373,354
Ensembl chr10:133,362,485...133,373,354
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ECI1 |
enoyl-CoA delta isomerase 1 |
increases expression affects expression |
ISO |
Fenofibrate results in increased expression of ECI1 mRNA Fenofibrate affects the expression of ECI1 mRNA |
CTD |
PMID:11798191 PMID:20801182 PMID:27665778 PMID:32741897 |
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NCBI chr16:2,239,402...2,251,587
Ensembl chr16:2,239,402...2,252,300
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ECI2 |
enoyl-CoA delta isomerase 2 |
increases expression |
ISO |
Fenofibrate results in increased expression of ECI2 mRNA |
CTD |
PMID:16707586 |
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NCBI chr 6:4,115,706...4,135,575
Ensembl chr 6:4,115,693...4,135,597
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EDN1 |
endothelin 1 |
multiple interactions |
ISO |
EDN1 protein promotes the reaction [Fenofibrate promotes the reaction [NFATC4 protein binds to PPARA protein]]; Fenofibrate inhibits the reaction [EDN1 protein promotes the reaction [NFATC4 protein binds to GATA4 protein]]; Fenofibrate inhibits the reaction [EDN1 protein promotes the reaction [NFATC4 protein binds to NPPB promoter]]; Fenofibrate inhibits the reaction [EDN1 protein results in increased expression of NPPB mRNA]; PPARA mutant form inhibits the reaction [Fenofibrate inhibits the reaction [EDN1 protein promotes the reaction [NFATC4 protein binds to GATA4 protein]]]; PPARA mutant form inhibits the reaction [Fenofibrate inhibits the reaction [EDN1 protein results in increased expression of NPPB mRNA]] Fenofibrate affects the reaction [[AHR protein affects the susceptibility to AGT protein] which affects the expression of EDN1 mRNA] |
CTD |
PMID:22198280 PMID:31016362 |
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NCBI chr 6:12,230,516...12,297,194
Ensembl chr 6:12,290,361...12,297,194
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EGFR |
epidermal growth factor receptor |
decreases expression |
ISO |
Fenofibrate results in decreased expression of EGFR mRNA |
CTD |
PMID:11798191 |
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NCBI chr 7:55,019,017...55,211,628
Ensembl chr 7:55,019,017...55,211,628
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EHHADH |
enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase |
increases expression affects expression |
ISO |
Fenofibrate results in increased expression of EHHADH mRNA Fenofibrate affects the expression of EHHADH mRNA |
CTD |
PMID:11798191 PMID:17118139 PMID:20801182 PMID:27665778 PMID:32741897 |
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NCBI chr 3:185,190,624...185,254,049
Ensembl chr 3:185,190,624...185,281,990
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EIF1 |
eukaryotic translation initiation factor 1 |
decreases expression increases expression |
ISO EXP |
Fenofibrate results in decreased expression of EIF1 mRNA Fenofibrate results in increased expression of EIF1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr17:41,688,885...41,692,668
Ensembl chr17:41,688,885...41,692,668
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EIF2AK3 |
eukaryotic translation initiation factor 2 alpha kinase 3 |
multiple interactions |
ISO |
Fenofibrate inhibits the reaction [Dietary Fats results in increased phosphorylation of EIF2AK3 protein] |
CTD |
PMID:38216941 |
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NCBI chr 2:88,556,741...88,628,145
Ensembl chr 2:88,556,741...88,691,518
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EIF2S2 |
eukaryotic translation initiation factor 2 subunit beta |
affects expression |
ISO |
Fenofibrate affects the expression of EIF2S2 mRNA |
CTD |
PMID:25596134 |
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NCBI chr20:34,088,309...34,112,243
Ensembl chr20:34,088,309...34,112,243
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EIF3C |
eukaryotic translation initiation factor 3 subunit C |
increases expression |
ISO |
Fenofibrate results in increased expression of EIF3C mRNA |
CTD |
PMID:25596134 |
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NCBI chr16:28,688,558...28,735,730
Ensembl chr16:28,688,558...28,735,727
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ELK4 |
ETS transcription factor ELK4 |
increases expression |
EXP |
Fenofibrate results in increased expression of ELK4 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 1:205,607,943...205,632,011
Ensembl chr 1:205,597,556...205,632,011
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ELOVL6 |
ELOVL fatty acid elongase 6 |
multiple interactions increases expression |
EXP ISO |
[Oleic Acid co-treated with Fenofibrate] affects the expression of ELOVL6 mRNA Fenofibrate results in increased expression of ELOVL6 mRNA NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ELOVL6 mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ELOVL6 mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ELOVL6 mRNA] |
CTD |
PMID:23063693 PMID:24534255 PMID:27665778 |
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NCBI chr 4:110,045,846...110,199,202
Ensembl chr 4:110,045,846...110,199,199
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ENC1 |
ectodermal-neural cortex 1 |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of ENC1 mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of ENC1 mRNA] |
CTD |
PMID:21318169 |
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NCBI chr 5:74,627,409...74,640,728
Ensembl chr 5:74,627,406...74,641,424
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ENO1 |
enolase 1 |
increases expression |
EXP |
Fenofibrate results in increased expression of ENO1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 1:8,861,000...8,878,686
Ensembl chr 1:8,861,000...8,879,190
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ENPP2 |
ectonucleotide pyrophosphatase/phosphodiesterase 2 |
decreases expression |
EXP |
Fenofibrate results in decreased expression of ENPP2 mRNA |
CTD |
PMID:25572481 |
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NCBI chr 8:119,557,086...119,673,390
Ensembl chr 8:119,557,086...119,673,453
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ENTPD7 |
ectonucleoside triphosphate diphosphohydrolase 7 |
decreases expression |
EXP |
Fenofibrate results in decreased expression of ENTPD7 mRNA |
CTD |
PMID:25596134 |
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NCBI chr10:99,659,509...99,711,241
Ensembl chr10:99,659,509...99,711,241
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EP400 |
E1A binding protein p400 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of EP400 mRNA |
CTD |
PMID:25596134 |
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NCBI chr12:131,949,942...132,080,460
Ensembl chr12:131,949,942...132,080,460
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EPHX2 |
epoxide hydrolase 2 |
affects expression increases expression |
ISO EXP |
Fenofibrate affects the expression of EPHX2 mRNA Fenofibrate results in increased expression of EPHX2 mRNA Fenofibrate affects the expression of EPHX2 protein |
CTD |
PMID:20801182 PMID:29960002 PMID:32741897 |
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NCBI chr 8:27,491,143...27,548,626
Ensembl chr 8:27,490,781...27,545,564
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EPRS1 |
glutamyl-prolyl-tRNA synthetase 1 |
increases expression |
EXP ISO |
Fenofibrate results in increased expression of EPRS1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 1:219,968,600...220,046,505
Ensembl chr 1:219,968,600...220,046,530
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ERO1A |
endoplasmic reticulum oxidoreductase 1 alpha |
increases expression |
ISO |
Fenofibrate results in increased expression of ERO1A mRNA |
CTD |
PMID:25596134 |
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NCBI chr14:52,639,915...52,695,558
Ensembl chr14:52,639,915...52,695,900
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ESR1 |
estrogen receptor 1 |
multiple interactions |
EXP |
[ESR1 protein results in increased susceptibility to Estradiol] inhibits the reaction [Fenofibrate results in decreased expression of CASP3 protein]; ESR1 protein inhibits the reaction [Estradiol inhibits the reaction [Fenofibrate inhibits the reaction [ESR1 protein binds to PPARA protein]]]; ESR1 protein inhibits the reaction [Fenofibrate inhibits the reaction [ESR1 protein binds to PPARA protein]]; ESR1 protein inhibits the reaction [Fenofibrate results in decreased expression of CDKN1B protein]; ESR1 protein inhibits the reaction [Fenofibrate results in increased expression of CCND1 protein]; ESR1 protein inhibits the reaction [Fenofibrate results in increased expression of PCNA protein]; Estradiol inhibits the reaction [ESR1 protein inhibits the reaction [Fenofibrate inhibits the reaction [ESR1 protein binds to PPARA protein]]]; Estradiol inhibits the reaction [Fenofibrate inhibits the reaction [ESR1 protein binds to PPARA protein]]; Fenofibrate inhibits the reaction [ESR1 protein binds to PPARA protein] |
CTD |
PMID:29134746 |
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NCBI chr 6:151,656,672...152,129,619
Ensembl chr 6:151,656,691...152,129,619
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G |
ETFA |
electron transfer flavoprotein subunit alpha |
increases expression |
EXP |
Fenofibrate results in increased expression of ETFA mRNA |
CTD |
PMID:25572481 |
|
NCBI chr15:76,215,353...76,311,469
Ensembl chr15:76,188,555...76,311,730
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G |
ETFDH |
electron transfer flavoprotein dehydrogenase |
decreases expression increases expression |
ISO EXP |
Fenofibrate results in decreased expression of ETFDH protein Fenofibrate results in increased expression of ETFDH mRNA |
CTD |
PMID:20118634 PMID:25572481 |
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NCBI chr 4:158,672,296...158,709,623
Ensembl chr 4:158,671,968...158,710,742
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G |
ETNK2 |
ethanolamine kinase 2 |
decreases expression |
EXP |
Fenofibrate results in decreased expression of ETNK2 mRNA |
CTD |
PMID:25572481 |
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NCBI chr 1:204,131,062...204,152,044
Ensembl chr 1:204,131,062...204,152,044
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G |
F2 |
coagulation factor II, thrombin |
multiple interactions |
EXP |
Fenofibrate promotes the reaction [Warfarin results in decreased expression of F2 protein] |
CTD |
PMID:9681093 |
|
NCBI chr11:46,719,213...46,739,506
Ensembl chr11:46,719,196...46,739,506
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G |
F7 |
coagulation factor VII |
multiple interactions |
EXP |
Fenofibrate promotes the reaction [Warfarin results in decreased expression of F7 protein] |
CTD |
PMID:9681093 |
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NCBI chr13:113,105,788...113,120,685
Ensembl chr13:113,105,788...113,120,685
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G |
FABP1 |
fatty acid binding protein 1 |
increases expression multiple interactions |
ISO EXP |
Fenofibrate results in increased expression of FABP1 mRNA Fenofibrate inhibits the reaction [Pyrazinamide results in decreased expression of FABP1 mRNA] |
CTD |
PMID:17118139 PMID:24752549 PMID:27071702 PMID:32741897 |
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NCBI chr 2:88,122,982...88,128,062
Ensembl chr 2:88,122,982...88,128,062
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G |
FABP2 |
fatty acid binding protein 2 |
increases expression |
ISO |
Fenofibrate results in increased expression of FABP2 mRNA |
CTD |
PMID:17118139 |
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NCBI chr 4:119,317,250...119,322,138
Ensembl chr 4:119,317,250...119,322,138
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G |
FABP3 |
fatty acid binding protein 3 |
increases expression |
ISO |
Fenofibrate results in increased expression of FABP3 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 1:31,359,588...31,373,076
Ensembl chr 1:31,365,253...31,376,850
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G |
FABP4 |
fatty acid binding protein 4 |
increases expression |
ISO EXP |
Fenofibrate results in increased expression of FABP4 mRNA |
CTD |
PMID:11798191 PMID:12759900 PMID:25572481 |
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NCBI chr 8:81,478,419...81,483,233
Ensembl chr 8:81,478,419...81,483,236
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G |
FADS1 |
fatty acid desaturase 1 |
multiple interactions increases expression |
EXP |
beta-hydroxy simvastatin acid promotes the reaction [Fenofibrate results in increased expression of FADS1 mRNA]; Fenofibrate promotes the reaction [beta-hydroxy simvastatin acid results in increased expression of FADS1 mRNA] |
CTD |
PMID:17655842 |
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NCBI chr11:61,799,627...61,817,003
Ensembl chr11:61,799,627...61,829,318
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G |
FAH |
fumarylacetoacetate hydrolase |
increases expression |
EXP |
Fenofibrate results in increased expression of FAH mRNA |
CTD |
PMID:25572481 |
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NCBI chr15:80,152,789...80,186,949
Ensembl chr15:80,152,490...80,186,946
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G |
FAM210A |
family with sequence similarity 210 member A |
affects expression |
ISO |
Fenofibrate affects the expression of FAM210A mRNA |
CTD |
PMID:25596134 |
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NCBI chr18:13,663,347...13,726,558
Ensembl chr18:13,663,347...13,726,663
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G |
FAM222A |
family with sequence similarity 222 member A |
increases expression |
EXP |
Fenofibrate results in increased expression of FAM222A mRNA |
CTD |
PMID:25572481 |
|
NCBI chr12:109,713,825...109,770,495
Ensembl chr12:109,713,825...109,770,495
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G |
FAM241A |
family with sequence similarity 241 member A |
increases expression |
EXP |
Fenofibrate results in increased expression of FAM241A mRNA |
CTD |
PMID:25572481 |
|
NCBI chr 4:112,145,454...112,195,256
Ensembl chr 4:112,145,454...112,195,256
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G |
FAM89A |
family with sequence similarity 89 member A |
increases expression |
EXP |
Fenofibrate results in increased expression of FAM89A mRNA |
CTD |
PMID:25596134 |
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NCBI chr 1:231,018,958...231,040,254
Ensembl chr 1:231,018,958...231,040,254
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G |
FAS |
Fas cell surface death receptor |
multiple interactions decreases expression |
ISO EXP |
Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of FAS mRNA]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of FAS mRNA]] fenofibrate co-treated with fructose diet increases expression of Fas mRNA in liver Fenofibrate results in decreased expression of FAS mRNA |
CTD RGD |
PMID:19593819 PMID:25596134 PMID:11934685 |
RGD:628329 |
NCBI chr10:88,964,050...89,017,059
Ensembl chr10:88,953,813...89,029,605
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G |
FASN |
fatty acid synthase |
multiple interactions increases expression |
EXP ISO |
[Oleic Acid co-treated with Fenofibrate] affects the expression of FASN mRNA; Fenofibrate inhibits the reaction [[Fructose co-treated with Palmitic Acid] results in increased expression of FASN protein] [Fenofibrate co-treated with resveratrol] inhibits the reaction [Fructose results in increased expression of FASN mRNA]; Fenofibrate inhibits the reaction [Fructose results in increased expression of FASN mRNA] Fenofibrate results in increased expression of FASN mRNA NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of FASN mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of FASN mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of FASN mRNA] |
CTD |
PMID:17118139 PMID:23063693 PMID:24534255 PMID:26973390 PMID:32730863 |
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NCBI chr17:82,078,338...82,098,236
Ensembl chr17:82,078,338...82,098,294
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G |
FBP2 |
fructose-bisphosphatase 2 |
increases expression |
ISO |
Fenofibrate results in increased expression of FBP2 mRNA |
CTD |
PMID:32741897 |
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NCBI chr 9:94,558,720...94,593,824
Ensembl chr 9:94,558,720...94,593,824
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G |
FBXO21 |
F-box protein 21 |
increases expression |
ISO |
Fenofibrate results in increased expression of FBXO21 mRNA |
CTD |
PMID:21318169 |
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NCBI chr12:117,141,991...117,190,470
Ensembl chr12:117,141,991...117,190,470
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G |
FBXO22 |
F-box protein 22 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of FBXO22 mRNA |
CTD |
PMID:25596134 |
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NCBI chr15:75,903,878...75,942,511
Ensembl chr15:75,903,876...75,942,511
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G |
FBXO3 |
F-box protein 3 |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of FBXO3 mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of FBXO3 mRNA] |
CTD |
PMID:21318169 |
|
NCBI chr11:33,740,944...33,774,520
Ensembl chr11:33,740,939...33,774,543
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G |
FBXO30 |
F-box protein 30 |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of FBXO30 mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of FBXO30 mRNA] |
CTD |
PMID:21318169 PMID:25596134 |
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NCBI chr 6:145,793,502...145,814,795
Ensembl chr 6:145,793,502...145,814,795
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G |
FBXO32 |
F-box protein 32 |
multiple interactions increases expression |
ISO |
Lovastatin promotes the reaction [Fenofibrate results in increased expression of FBXO32 protein]; PPARA protein affects the reaction [Fenofibrate results in increased expression of FBXO32 mRNA] Fenofibrate results in increased expression of FBXO32 mRNA; Fenofibrate results in increased expression of FBXO32 protein |
CTD |
PMID:33408297 |
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NCBI chr 8:123,497,889...123,541,206
Ensembl chr 8:123,497,889...123,541,206
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G |
FBXO36 |
F-box protein 36 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of FBXO36 mRNA |
CTD |
PMID:21318169 |
|
NCBI chr 2:229,922,503...230,013,119
Ensembl chr 2:229,922,302...230,013,119
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G |
FBXO9 |
F-box protein 9 |
increases expression |
ISO |
Fenofibrate results in increased expression of FBXO9 mRNA |
CTD |
PMID:21318169 |
|
NCBI chr 6:53,064,998...53,100,873
Ensembl chr 6:53,051,991...53,100,873
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G |
FDFT1 |
farnesyl-diphosphate farnesyltransferase 1 |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of FDFT1 mRNA NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of FDFT1 mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of FDFT1 mRNA] |
CTD |
PMID:23063693 |
|
NCBI chr 8:11,795,582...11,839,298
Ensembl chr 8:11,795,573...11,839,395
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G |
FGA |
fibrinogen alpha chain |
multiple interactions decreases expression |
ISO |
PPARA promotes the reaction [Fenofibrate results in decreased expression of FGA mRNA] |
CTD |
PMID:10216095 |
|
NCBI chr 4:154,583,126...154,590,742
Ensembl chr 4:154,583,126...154,590,742
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G |
FGB |
fibrinogen beta chain |
decreases expression |
ISO |
Fenofibrate results in decreased expression of FGB mRNA |
CTD |
PMID:10216095 |
|
NCBI chr 4:154,562,980...154,572,807
Ensembl chr 4:154,563,011...154,572,807
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G |
FGF21 |
fibroblast growth factor 21 |
increases expression |
EXP |
Fenofibrate results in increased expression of FGF21 mRNA; Fenofibrate results in increased expression of FGF21 protein |
CTD |
PMID:22338096 |
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NCBI chr19:48,755,524...48,758,330
Ensembl chr19:48,755,524...48,758,333
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G |
FGG |
fibrinogen gamma chain |
decreases expression |
ISO |
Fenofibrate results in decreased expression of FGG mRNA |
CTD |
PMID:10216095 |
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NCBI chr 4:154,604,136...154,612,656
Ensembl chr 4:154,604,134...154,612,967
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G |
FGR |
FGR proto-oncogene, Src family tyrosine kinase |
affects expression |
ISO |
Fenofibrate affects the expression of FGR mRNA |
CTD |
PMID:25596134 |
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NCBI chr 1:27,612,064...27,635,185
Ensembl chr 1:27,612,064...27,635,185
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G |
FIS1 |
fission, mitochondrial 1 |
multiple interactions |
EXP |
Fenofibrate inhibits the reaction [[Fructose co-treated with Palmitic Acid] results in increased expression of FIS1 protein] |
CTD |
PMID:32730863 |
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NCBI chr 7:101,239,472...101,245,081
Ensembl chr 7:101,239,458...101,252,316
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G |
FKBP15 |
FKBP prolyl isomerase family member 15 |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of FKBP15 mRNA [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of FKBP15 mRNA |
CTD |
PMID:21318169 |
|
NCBI chr 9:113,161,006...113,221,277
Ensembl chr 9:113,161,006...113,221,458
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G |
FKBP8 |
FKBP prolyl isomerase 8 |
increases expression |
ISO |
Fenofibrate results in increased expression of FKBP8 mRNA |
CTD |
PMID:21318169 |
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NCBI chr19:18,531,763...18,543,573
Ensembl chr19:18,531,751...18,544,077
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G |
FMO1 |
flavin containing dimethylaniline monoxygenase 1 |
multiple interactions |
ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of FMO1 mRNA |
CTD |
PMID:18253720 |
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NCBI chr 1:171,248,494...171,285,978
Ensembl chr 1:171,248,471...171,285,978
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G |
FMO5 |
flavin containing dimethylaniline monoxygenase 5 |
multiple interactions decreases expression |
ISO EXP |
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of FMO5 mRNA Fenofibrate results in decreased expression of FMO5 mRNA |
CTD |
PMID:18253720 PMID:25572481 |
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NCBI chr 1:147,184,305...147,227,284
Ensembl chr 1:147,175,351...147,243,050
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G |
FN1 |
fibronectin 1 |
affects expression multiple interactions |
ISO |
Fenofibrate affects the expression of FN1 mRNA Fenofibrate inhibits the reaction [zoledronic acid results in increased expression of FN1 protein] |
CTD |
PMID:20801182 PMID:28871336 |
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NCBI chr 2:215,360,865...215,436,068
Ensembl chr 2:215,360,440...215,436,073
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G |
FOXO1 |
forkhead box O1 |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of FOXO1 mRNA; Fenofibrate results in increased expression of FOXO1 protein Lovastatin promotes the reaction [Fenofibrate results in increased expression of FOXO1 protein]; PPARA protein affects the reaction [Fenofibrate results in increased expression of FOXO1 mRNA] |
CTD |
PMID:33408297 |
|
NCBI chr13:40,555,667...40,666,641
Ensembl chr13:40,555,667...40,666,641
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G |
FOXQ1 |
forkhead box Q1 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of FOXQ1 mRNA |
CTD |
PMID:11798191 |
|
NCBI chr 6:1,312,098...1,314,758
Ensembl chr 6:1,312,098...1,314,758
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G |
G6PC1 |
glucose-6-phosphatase catalytic subunit 1 |
decreases expression |
EXP |
Fenofibrate results in decreased expression of G6PC1 mRNA |
CTD |
PMID:25572481 |
|
NCBI chr17:42,900,799...42,914,438
Ensembl chr17:42,900,797...42,914,438
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G |
GADD45A |
growth arrest and DNA damage inducible alpha |
multiple interactions increases expression |
ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of GADD45A mRNA Fenofibrate results in increased expression of GADD45A mRNA |
CTD |
PMID:17264098 PMID:18253720 PMID:18775883 PMID:25596134 |
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NCBI chr 1:67,685,201...67,688,334
Ensembl chr 1:67,685,201...67,688,334
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G |
GADD45B |
growth arrest and DNA damage inducible beta |
multiple interactions |
ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of GADD45B mRNA |
CTD |
PMID:18253720 |
|
NCBI chr19:2,476,127...2,478,257
Ensembl chr19:2,476,122...2,478,805
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G |
GALT |
galactose-1-phosphate uridylyltransferase |
increases expression |
EXP |
Fenofibrate results in increased expression of GALT mRNA |
CTD |
PMID:25572481 |
|
NCBI chr 9:34,646,675...34,651,035
Ensembl chr 9:34,638,133...34,651,035
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G |
GARS1 |
glycyl-tRNA synthetase 1 |
increases expression |
EXP |
Fenofibrate results in increased expression of GARS1 mRNA |
CTD |
PMID:25596134 |
|
NCBI chr 7:30,594,735...30,634,033
Ensembl chr 7:30,580,533...30,634,033
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G |
GATA4 |
GATA binding protein 4 |
multiple interactions |
ISO |
Fenofibrate inhibits the reaction [EDN1 protein promotes the reaction [NFATC4 protein binds to GATA4 protein]]; PPARA mutant form inhibits the reaction [Fenofibrate inhibits the reaction [EDN1 protein promotes the reaction [NFATC4 protein binds to GATA4 protein]]] |
CTD |
PMID:22198280 |
|
NCBI chr 8:11,676,935...11,760,002
Ensembl chr 8:11,676,959...11,760,002
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G |
GBE1 |
1,4-alpha-glucan branching enzyme 1 |
decreases expression increases expression |
ISO EXP |
Fenofibrate results in decreased expression of GBE1 mRNA Fenofibrate results in increased expression of GBE1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 3:81,489,703...81,761,645
Ensembl chr 3:81,489,703...81,761,645
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G |
GCAT |
glycine C-acetyltransferase |
decreases expression |
EXP |
Fenofibrate results in decreased expression of GCAT mRNA |
CTD |
PMID:25572481 |
|
NCBI chr22:37,807,934...37,817,183
Ensembl chr22:37,807,905...37,817,176
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G |
GCLC |
glutamate-cysteine ligase catalytic subunit |
decreases expression multiple interactions |
ISO |
Fenofibrate results in decreased expression of GCLC mRNA Fenofibrate inhibits the reaction [tyloxapol results in decreased expression of GCLC protein] |
CTD |
PMID:25596134 PMID:36905866 |
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NCBI chr 6:53,497,341...53,545,101
Ensembl chr 6:53,497,341...53,616,970
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G |
GCLM |
glutamate-cysteine ligase modifier subunit |
increases expression |
EXP |
Fenofibrate results in increased expression of GCLM mRNA |
CTD |
PMID:25596134 |
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NCBI chr 1:93,885,199...93,909,430
Ensembl chr 1:93,885,199...93,909,456
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G |
GCNT3 |
glucosaminyl (N-acetyl) transferase 3, mucin type |
increases expression |
EXP |
Fenofibrate results in increased expression of GCNT3 mRNA |
CTD |
PMID:25596134 |
|
NCBI chr15:59,611,783...59,622,723
Ensembl chr15:59,594,875...59,640,239
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G |
GDE1 |
glycerophosphodiester phosphodiesterase 1 |
affects expression |
ISO |
Fenofibrate affects the expression of GDE1 mRNA |
CTD |
PMID:20801182 |
|
NCBI chr16:19,501,693...19,522,098
Ensembl chr16:19,501,693...19,522,123
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G |
GDF15 |
growth differentiation factor 15 |
increases expression |
EXP ISO |
Fenofibrate results in increased expression of GDF15 mRNA |
CTD |
PMID:25596134 |
|
NCBI chr19:18,386,158...18,389,176
Ensembl chr19:18,374,731...18,389,176
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G |
GK |
glycerol kinase |
increases expression |
EXP ISO |
Fenofibrate results in increased expression of GK mRNA |
CTD |
PMID:25572481 PMID:32741897 |
|
NCBI chr X:30,653,423...30,731,462
Ensembl chr X:30,653,359...30,731,462
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G |
GMNN |
geminin DNA replication inhibitor |
increases expression |
ISO |
Fenofibrate results in increased expression of GMNN mRNA |
CTD |
PMID:32741897 |
|
NCBI chr 6:24,774,937...24,786,099
Ensembl chr 6:24,774,931...24,786,099
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G |
GNMT |
glycine N-methyltransferase |
decreases expression |
EXP |
Fenofibrate results in decreased expression of GNMT mRNA |
CTD |
PMID:25572481 |
|
NCBI chr 6:42,960,754...42,963,880
Ensembl chr 6:42,960,754...42,963,880
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G |
GOT1 |
glutamic-oxaloacetic transaminase 1 |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of GOT1 mRNA Fenofibrate inhibits the reaction [Dietary Fats results in increased expression of GOT1 protein] |
CTD |
PMID:25596134 PMID:38216941 |
|
NCBI chr10:99,396,870...99,430,624
Ensembl chr10:99,396,870...99,430,624
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G |
GOT2 |
glutamic-oxaloacetic transaminase 2 |
increases expression |
ISO |
Fenofibrate results in increased expression of GOT2 mRNA |
CTD |
PMID:19652460 |
|
NCBI chr16:58,707,131...58,734,316
Ensembl chr16:58,707,131...58,734,342
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G |
GPAM |
glycerol-3-phosphate acyltransferase, mitochondrial |
increases expression |
ISO |
Fenofibrate results in increased expression of GPAM mRNA |
CTD |
PMID:16707586 |
|
NCBI chr10:112,149,865...112,227,677
Ensembl chr10:112,149,865...112,215,377
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G |
GPAT3 |
glycerol-3-phosphate acyltransferase 3 |
increases expression |
EXP |
Fenofibrate results in increased expression of GPAT3 mRNA |
CTD |
PMID:25596134 |
|
NCBI chr 4:83,535,587...83,605,875
Ensembl chr 4:83,535,914...83,605,875
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G |
GPHN |
gephyrin |
increases expression |
ISO EXP |
Fenofibrate results in increased expression of GPHN mRNA |
CTD |
PMID:25596134 |
|
NCBI chr14:66,508,147...67,735,355
Ensembl chr14:66,507,407...67,181,803
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G |
GPT |
glutamic--pyruvic transaminase |
multiple interactions |
ISO |
Fenofibrate inhibits the reaction [Dietary Fats results in increased expression of GPT protein]; Fenofibrate inhibits the reaction [Pyrazinamide results in increased expression of GPT protein] Fenofibrate inhibits the reaction [tyloxapol results in increased expression of GPT protein] |
CTD |
PMID:27071702 PMID:36905866 PMID:38216941 |
|
NCBI chr 8:144,503,068...144,507,172
Ensembl chr 8:144,502,973...144,507,174
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G |
GPX1 |
glutathione peroxidase 1 |
multiple interactions |
ISO |
Fenofibrate inhibits the reaction [triptolide results in increased expression of GPX1 mRNA] |
CTD |
PMID:31241159 |
|
NCBI chr 3:49,357,176...49,358,353
Ensembl chr 3:49,357,174...49,358,605
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|
G |
GPX2 |
glutathione peroxidase 2 |
multiple interactions increases expression |
ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of GPX2 mRNA Fenofibrate inhibits the reaction [triptolide results in increased expression of GPX2 mRNA] Fenofibrate results in increased expression of GPX2 mRNA |
CTD |
PMID:17264098 PMID:18253720 PMID:18775883 PMID:31241159 |
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NCBI chr14:64,939,158...64,942,745
Ensembl chr14:64,939,152...64,942,746
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G |
GPX3 |
glutathione peroxidase 3 |
multiple interactions |
ISO |
Fenofibrate inhibits the reaction [triptolide results in increased expression of GPX3 mRNA] |
CTD |
PMID:31241159 |
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NCBI chr 5:151,020,591...151,028,988
Ensembl chr 5:151,020,591...151,028,988
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G |
GPX4 |
glutathione peroxidase 4 |
multiple interactions |
ISO |
Fenofibrate inhibits the reaction [triptolide results in increased expression of GPX4 mRNA] |
CTD |
PMID:31241159 |
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NCBI chr19:1,103,994...1,106,779
Ensembl chr19:1,103,982...1,106,791
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G |
GRM3 |
glutamate metabotropic receptor 3 |
increases expression |
EXP |
Fenofibrate results in increased expression of GRM3 mRNA |
CTD |
PMID:25572481 |
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NCBI chr 7:86,643,909...86,864,879
Ensembl chr 7:86,643,909...86,864,879
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G |
GRPEL2 |
GrpE like 2, mitochondrial |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of GRPEL2 mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of GRPEL2 mRNA] |
CTD |
PMID:21318169 |
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NCBI chr 5:149,345,499...149,354,583
Ensembl chr 5:149,345,430...149,354,583
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G |
GSR |
glutathione-disulfide reductase |
increases expression |
ISO |
Fenofibrate results in increased expression of GSR mRNA |
CTD |
PMID:25596134 |
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NCBI chr 8:30,678,066...30,727,846
Ensembl chr 8:30,678,066...30,727,846
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G |
GSTA2 |
glutathione S-transferase alpha 2 |
decreases expression multiple interactions |
ISO |
Fenofibrate results in decreased expression of GSTA2 mRNA [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of GSTA2 mRNA |
CTD |
PMID:18253720 PMID:18775883 |
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NCBI chr 6:52,750,087...52,763,475
Ensembl chr 6:52,750,087...52,763,475
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G |
GSTA5 |
glutathione S-transferase alpha 5 |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of GSTA5 mRNA [Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of GSTA5 mRNA |
CTD |
PMID:17264098 PMID:18253720 PMID:18775883 |
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NCBI chr 6:52,831,692...52,846,245
Ensembl chr 6:52,831,655...52,840,843
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G |
GSTM2 |
glutathione S-transferase mu 2 |
multiple interactions decreases expression |
ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of GSTM2 mRNA Fenofibrate results in decreased expression of GSTM2 mRNA |
CTD |
PMID:18253720 PMID:18775883 |
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NCBI chr 1:109,668,057...109,683,997
Ensembl chr 1:109,668,022...109,709,551
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G |
GSTM3 |
glutathione S-transferase mu 3 |
multiple interactions decreases expression |
ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of GSTM3 mRNA Fenofibrate results in decreased expression of GSTM3 mRNA |
CTD |
PMID:18253720 PMID:18775883 |
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NCBI chr 1:109,733,937...109,741,038
Ensembl chr 1:109,733,932...109,741,038
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G |
GSTP1 |
glutathione S-transferase pi 1 |
multiple interactions |
EXP |
Fenofibrate inhibits the reaction [GSTP1 protein results in increased metabolism of 1-chloro-2,4-dinitrobenzene-glutathione conjugate] |
CTD |
PMID:23769903 |
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NCBI chr11:67,583,812...67,586,653
Ensembl chr11:67,583,742...67,586,656
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G |
GTSE1 |
G2 and S-phase expressed 1 |
increases expression |
ISO |
Fenofibrate results in increased expression of GTSE1 mRNA |
CTD |
PMID:32741897 |
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NCBI chr22:46,296,870...46,330,810
Ensembl chr22:46,296,870...46,330,810
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G |
H1-2 |
H1.2 linker histone, cluster member |
decreases expression |
EXP |
Fenofibrate results in decreased expression of H1-2 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 6:26,055,740...26,056,470
Ensembl chr 6:26,054,760...26,056,470
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G |
HADH |
hydroxyacyl-CoA dehydrogenase |
increases expression |
EXP |
Fenofibrate results in increased expression of HADH mRNA |
CTD |
PMID:24752549 |
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NCBI chr 4:107,989,889...108,035,171
Ensembl chr 4:107,989,714...108,035,241
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G |
HADHA |
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha |
increases expression decreases expression |
ISO EXP |
Fenofibrate results in increased expression of HADHA mRNA Fenofibrate results in decreased expression of HADHA protein |
CTD |
PMID:16707586 PMID:17118139 PMID:20118634 PMID:25572481 |
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NCBI chr 2:26,190,635...26,244,632
Ensembl chr 2:26,190,635...26,244,672
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G |
HADHB |
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta |
increases expression decreases expression affects expression |
ISO EXP |
Fenofibrate results in increased expression of HADHB mRNA Fenofibrate results in decreased expression of HADHB protein Fenofibrate affects the expression of HADHB mRNA |
CTD |
PMID:17118139 PMID:20118634 PMID:20801182 PMID:24752549 PMID:25572481 |
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NCBI chr 2:26,244,939...26,290,465
Ensembl chr 2:26,243,170...26,290,465
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G |
HAL |
histidine ammonia-lyase |
decreases expression |
ISO |
Fenofibrate results in decreased expression of HAL mRNA |
CTD |
PMID:32741898 |
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NCBI chr12:95,972,662...95,996,344
Ensembl chr12:95,972,662...95,996,365
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G |
HDC |
histidine decarboxylase |
increases expression |
ISO |
Fenofibrate results in increased expression of HDC mRNA; Fenofibrate results in increased expression of HDC protein |
CTD |
PMID:32741897 PMID:32741898 |
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NCBI chr15:50,241,947...50,265,726
Ensembl chr15:50,241,947...50,265,965
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G |
HDGFL3 |
HDGF like 3 |
increases expression |
ISO |
Fenofibrate results in increased expression of HDGFL3 mRNA |
CTD |
PMID:17264098 |
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NCBI chr15:83,112,738...83,207,823
Ensembl chr15:83,112,738...83,207,875
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G |
HECTD1 |
HECT domain E3 ubiquitin protein ligase 1 |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of HECTD1 mRNA [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of HECTD1 mRNA |
CTD |
PMID:21318169 |
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NCBI chr14:31,100,117...31,207,793
Ensembl chr14:31,100,117...31,207,804
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G |
HERC3 |
HECT and RLD domain containing E3 ubiquitin protein ligase 3 |
increases expression |
EXP |
Fenofibrate results in increased expression of HERC3 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 4:88,523,843...88,708,539
Ensembl chr 4:88,523,810...88,708,450 Ensembl chr 4:88,523,810...88,708,450
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G |
HES1 |
hes family bHLH transcription factor 1 |
multiple interactions |
ISO |
Fenofibrate inhibits the reaction [triptolide results in increased expression of HES1 mRNA] |
CTD |
PMID:31241159 |
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NCBI chr 3:194,136,148...194,138,732
Ensembl chr 3:194,136,148...194,138,732
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G |
HIF1A |
hypoxia inducible factor 1 subunit alpha |
increases expression multiple interactions affects activity |
ISO EXP |
Fenofibrate results in increased expression of HIF1A mRNA Fenofibrate inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]; Fenofibrate results in decreased expression of and results in increased degradation of HIF1A protein Fenofibrate affects the activity of HIF1A protein |
CTD |
PMID:17118139 PMID:25596134 PMID:34520103 |
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NCBI chr14:61,695,513...61,748,258
Ensembl chr14:61,695,513...61,748,259
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G |
HILPDA |
hypoxia inducible lipid droplet associated |
increases expression |
ISO |
Fenofibrate results in increased expression of HILPDA mRNA |
CTD |
PMID:32741897 |
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NCBI chr 7:128,455,878...128,458,418
Ensembl chr 7:128,455,849...128,458,418
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G |
HLA-A |
major histocompatibility complex, class I, A |
affects response to substance |
EXP |
HLA-A gene polymorphism affects the susceptibility to Fenofibrate |
CTD |
PMID:28043905 |
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NCBI chr 6:29,942,532...29,945,870
Ensembl chr 6:29,941,260...29,949,572
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G |
HLA-DRB1 |
major histocompatibility complex, class II, DR beta 1 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of H2-EB1 mRNA |
CTD |
PMID:11798191 |
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NCBI chr 6:32,578,775...32,589,848
Ensembl chr 6:32,577,902...32,589,848
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G |
HMGCR |
3-hydroxy-3-methylglutaryl-CoA reductase |
increases expression decreases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of HMGCR mRNA Fenofibrate results in decreased expression of HMGCR mRNA NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of HMGCR mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of HMGCR mRNA] |
CTD |
PMID:16595124 PMID:23063693 |
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NCBI chr 5:75,336,529...75,362,116
Ensembl chr 5:75,336,329...75,364,001
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G |
HMGCS1 |
3-hydroxy-3-methylglutaryl-CoA synthase 1 |
increases expression |
ISO |
Fenofibrate results in increased expression of HMGCS1 mRNA |
CTD |
PMID:11798191 |
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NCBI chr 5:43,287,470...43,313,412
Ensembl chr 5:43,287,470...43,313,512
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G |
HMGCS2 |
3-hydroxy-3-methylglutaryl-CoA synthase 2 |
increases expression |
EXP ISO |
Fenofibrate results in increased expression of HMGCS2 mRNA |
CTD |
PMID:25572481 PMID:27665778 PMID:32741897 |
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NCBI chr 1:119,747,996...119,768,932
Ensembl chr 1:119,748,002...119,768,905
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G |
HMOX1 |
heme oxygenase 1 |
increases expression multiple interactions |
ISO EXP |
Fenofibrate results in increased expression of HMOX1 mRNA dorsomorphin inhibits the reaction [Fenofibrate results in increased expression of HMOX1 protein] Fenofibrate results in increased expression of HMOX1 mRNA; Fenofibrate results in increased expression of HMOX1 protein |
CTD |
PMID:25596134 PMID:34520103 |
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NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214
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G |
HOGA1 |
4-hydroxy-2-oxoglutarate aldolase 1 |
decreases expression |
EXP |
Fenofibrate results in decreased expression of HOGA1 mRNA |
CTD |
PMID:25572481 |
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NCBI chr10:97,584,389...97,612,802
Ensembl chr10:97,584,323...97,612,802
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G |
HRAS |
HRas proto-oncogene, GTPase |
multiple interactions |
ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of HRAS mRNA |
CTD |
PMID:18978307 |
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NCBI chr11:532,242...535,576
Ensembl chr11:532,242...537,321
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G |
HSD11B1 |
hydroxysteroid 11-beta dehydrogenase 1 |
increases expression |
EXP |
Fenofibrate results in increased expression of HSD11B1 mRNA |
CTD |
PMID:25572481 |
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NCBI chr 1:209,686,179...209,734,929
Ensembl chr 1:209,686,178...209,734,949
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G |
HSD17B4 |
hydroxysteroid 17-beta dehydrogenase 4 |
increases expression |
ISO EXP |
Fenofibrate results in increased expression of HSD17B4 mRNA |
CTD |
PMID:17118139 PMID:25572481 |
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NCBI chr 5:119,452,497...119,542,332
Ensembl chr 5:119,452,465...119,637,199
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G |
HSDL2 |
hydroxysteroid dehydrogenase like 2 |
increases expression |
ISO |
Fenofibrate results in increased expression of HSDL2 mRNA |
CTD |
PMID:32741897 |
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NCBI chr 9:112,380,108...112,472,405
Ensembl chr 9:112,380,080...112,472,405
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G |
HSF1 |
heat shock transcription factor 1 |
multiple interactions |
ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of HSF1 mRNA |
CTD |
PMID:18253720 |
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NCBI chr 8:144,291,604...144,314,720
Ensembl chr 8:144,291,591...144,314,720
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G |
HSP90AA1 |
heat shock protein 90 alpha family class A member 1 |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of HSP90AA1 mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of HSP90AA1 mRNA] |
CTD |
PMID:21318169 |
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NCBI chr14:102,080,742...102,139,749
Ensembl chr14:102,080,742...102,139,699
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G |
HSP90AB1 |
heat shock protein 90 alpha family class B member 1 |
multiple interactions increases expression |
ISO |
PPARA protein affects the reaction [Fenofibrate results in increased expression of HSP90AB1 mRNA] |
CTD |
PMID:21318169 |
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NCBI chr 6:44,246,194...44,253,883
Ensembl chr 6:44,246,166...44,253,888
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G |
HSP90B1 |
heat shock protein 90 beta family member 1 |
increases expression |
ISO |
Fenofibrate results in increased expression of HSP90B1 mRNA |
CTD |
PMID:21318169 |
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NCBI chr12:103,930,410...103,947,926
Ensembl chr12:103,930,107...103,953,931
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G |
HSPA13 |
heat shock protein family A (Hsp70) member 13 |
decreases expression multiple interactions |
ISO |
Fenofibrate results in decreased expression of HSPA13 mRNA PPARA protein affects the reaction [Fenofibrate results in decreased expression of HSPA13 mRNA] |
CTD |
PMID:21318169 |
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NCBI chr21:14,371,115...14,383,146
Ensembl chr21:14,371,115...14,383,484
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G |
HSPA4L |
heat shock protein family A (Hsp70) member 4 like |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of HSPA4L mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of HSPA4L mRNA] |
CTD |
PMID:21318169 |
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NCBI chr 4:127,781,796...127,840,733
Ensembl chr 4:127,781,821...127,840,733
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G |
HSPA5 |
heat shock protein family A (Hsp70) member 5 |
decreases expression multiple interactions |
ISO |
Fenofibrate results in decreased expression of HSPA5 mRNA Fenofibrate inhibits the reaction [Dietary Fats results in increased expression of HSPA5 protein] |
CTD |
PMID:25596134 PMID:38216941 |
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NCBI chr 9:125,234,853...125,241,343
Ensembl chr 9:125,234,853...125,241,382
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G |
HSPA8 |
heat shock protein family A (Hsp70) member 8 |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of HSPA8 mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of HSPA8 mRNA] |
CTD |
PMID:21318169 |
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NCBI chr11:123,057,489...123,062,462
Ensembl chr11:123,057,489...123,063,230
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G |
HSPA9 |
heat shock protein family A (Hsp70) member 9 |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of HSPA9 mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of HSPA9 mRNA] |
CTD |
PMID:21318169 |
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NCBI chr 5:138,553,756...138,575,401
Ensembl chr 5:138,553,756...138,575,675
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G |
HSPB1 |
heat shock protein family B (small) member 1 |
affects expression multiple interactions increases expression |
ISO |
Fenofibrate affects the expression of HSPB1 mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of HSPB1 mRNA] |
CTD |
PMID:20801182 PMID:21318169 |
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NCBI chr 7:76,302,673...76,304,292
Ensembl chr 7:76,302,673...76,305,813
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G |
HSPB8 |
heat shock protein family B (small) member 8 |
multiple interactions increases expression |
ISO |
[PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of HSPB8 mRNA Fenofibrate results in increased expression of HSPB8 mRNA |
CTD |
PMID:21318169 |
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NCBI chr12:119,178,931...119,194,746
Ensembl chr12:119,171,555...119,224,855
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G |
HSPE1 |
heat shock protein family E (Hsp10) member 1 |
affects expression |
ISO |
Fenofibrate affects the expression of HSPE1 mRNA |
CTD |
PMID:20801182 |
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NCBI chr 2:197,500,379...197,503,449
Ensembl chr 2:197,500,140...197,503,449
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G |
HSPH1 |
heat shock protein family H (Hsp110) member 1 |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of HSPH1 mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of HSPH1 mRNA] |
CTD |
PMID:21318169 |
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NCBI chr13:31,134,973...31,162,388
Ensembl chr13:31,134,973...31,162,388
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G |
HTATIP2 |
HIV-1 Tat interactive protein 2 |
increases expression |
ISO |
Fenofibrate results in increased expression of HTATIP2 mRNA |
CTD |
PMID:25596134 |
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NCBI chr11:20,363,714...20,383,782
Ensembl chr11:20,363,685...20,383,782
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G |
IARS1 |
isoleucyl-tRNA synthetase 1 |
increases expression |
ISO EXP |
Fenofibrate results in increased expression of IARS1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 9:92,210,207...92,293,697
Ensembl chr 9:92,210,207...92,293,854
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G |
ICAM1 |
intercellular adhesion molecule 1 |
multiple interactions |
ISO EXP |
Fenofibrate inhibits the reaction [Lipopolysaccharides results in increased expression of ICAM1 mRNA] dorsomorphin inhibits the reaction [Fenofibrate inhibits the reaction [ALB protein modified form results in increased expression of ICAM1 mRNA]]; Fenofibrate inhibits the reaction [ALB protein modified form results in increased expression of ICAM1 mRNA] |
CTD |
PMID:20580385 PMID:21300114 |
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NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615
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G |
ID2 |
inhibitor of DNA binding 2 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of ID2 mRNA |
CTD |
PMID:11798191 |
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NCBI chr 2:8,682,056...8,684,461
Ensembl chr 2:8,678,845...8,684,461
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G |
IDH3B |
isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta |
increases expression |
EXP |
Fenofibrate results in increased expression of IDH3B mRNA |
CTD |
PMID:24752549 |
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NCBI chr20:2,658,395...2,664,216
Ensembl chr20:2,658,393...2,664,219
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G |
IFFO1 |
intermediate filament family orphan 1 |
increases expression |
ISO |
Fenofibrate results in increased expression of IFFO1 mRNA |
CTD |
PMID:16707586 |
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NCBI chr12:6,538,961...6,556,042
Ensembl chr12:6,538,961...6,556,073
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G |
IFNG |
interferon gamma |
multiple interactions |
ISO |
Fenofibrate results in decreased susceptibility to [IFNG protein co-treated with IL1B protein] |
CTD |
PMID:20631892 |
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NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740
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G |
IGF2R |
insulin like growth factor 2 receptor |
decreases expression |
ISO |
Fenofibrate results in decreased expression of IGF2R mRNA |
CTD |
PMID:25596134 |
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NCBI chr 6:159,969,082...160,111,504
Ensembl chr 6:159,969,082...160,113,507
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G |
IL12B |
interleukin 12B |
multiple interactions |
ISO |
Fenofibrate inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein] |
CTD |
PMID:15968640 |
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NCBI chr 5:159,314,780...159,330,487
Ensembl chr 5:159,314,780...159,330,863
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G |
IL17RB |
interleukin 17 receptor B |
decreases expression |
ISO |
Fenofibrate results in decreased expression of IL17RB mRNA |
CTD |
PMID:25596134 |
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NCBI chr 3:53,846,568...53,865,794
Ensembl chr 3:53,846,568...53,865,794
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G |
IL1B |
interleukin 1 beta |
multiple interactions |
ISO EXP |
[Fenofibrate co-treated with Alitretinoin] inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]; Fenofibrate inhibits the reaction [Cyclophosphamide results in increased expression of IL1B protein]; Fenofibrate inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; Fenofibrate inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]; Fenofibrate inhibits the reaction [triptolide results in increased expression of IL1B mRNA] Fenofibrate affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA]; Fenofibrate inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of CD36 mRNA]; Fenofibrate inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein] Fenofibrate inhibits the reaction [Doxorubicin results in increased expression of IL1B protein]; Fenofibrate promotes the reaction [Pioglitazone inhibits the reaction [Doxorubicin results in increased expression of IL1B protein]]; Fenofibrate results in decreased susceptibility to [IFNG protein co-treated with IL1B protein]; Pioglitazone promotes the reaction [Fenofibrate inhibits the reaction [Doxorubicin results in increased expression of IL1B protein]] |
CTD |
PMID:15968640 PMID:20631892 PMID:21300114 PMID:31241159 PMID:32613381 PMID:36988379 PMID:38278497 More...
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NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816
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G |
IL6 |
interleukin 6 |
multiple interactions affects response to substance |
ISO EXP |
[Fenofibrate co-treated with Alitretinoin] inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]; Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of IL6 mRNA]; Fenofibrate inhibits the reaction [Cyclophosphamide results in increased expression of IL6 protein]; Fenofibrate inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; Fenofibrate inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]; Fenofibrate inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]; Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of IL6 mRNA]; Fenofibrate inhibits the reaction [triptolide results in increased expression of IL6 mRNA]; Fenofibrate inhibits the reaction [tyloxapol results in increased expression of IL6 mRNA]; Fenofibrate promotes the reaction [Dextran Sulfate results in increased expression of IL6 protein]; NR0B2 protein inhibits the reaction [Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of IL6 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of IL6 mRNA]] IL6 promoter polymorphism affects the susceptibility to Fenofibrate |
CTD |
PMID:15968640 PMID:16607077 PMID:19593819 PMID:21300114 PMID:25035112 PMID:31241159 PMID:37076581 PMID:38278497 More...
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NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002
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INS |
insulin |
multiple interactions |
EXP |
Fenofibrate affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA]; Fenofibrate inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of CD36 mRNA]; Fenofibrate inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein] |
CTD |
PMID:32613381 |
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NCBI chr11:2,159,779...2,161,209
Ensembl chr11:2,159,779...2,161,221
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INS-IGF2 |
INS-IGF2 readthrough |
multiple interactions |
ISO |
Fenofibrate inhibits the reaction [Fructose results in increased secretion of INS1 protein] |
CTD |
PMID:26973390 |
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NCBI chr11:2,129,117...2,161,209
Ensembl chr11:2,132,538...2,161,209
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INSIG1 |
insulin induced gene 1 |
decreases expression |
EXP |
Fenofibrate results in decreased expression of INSIG1 mRNA |
CTD |
PMID:25572481 |
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NCBI chr 7:155,297,878...155,310,235
Ensembl chr 7:155,297,776...155,310,235
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INSIG2 |
insulin induced gene 2 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of INSIG2 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 2:118,088,471...118,110,997
Ensembl chr 2:118,088,452...118,110,997
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IRAK2 |
interleukin 1 receptor associated kinase 2 |
increases expression |
EXP |
Fenofibrate results in increased expression of IRAK2 mRNA |
CTD |
PMID:25572481 |
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NCBI chr 3:10,164,919...10,243,745
Ensembl chr 3:10,164,919...10,243,745
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IRF7 |
interferon regulatory factor 7 |
increases expression |
EXP |
Fenofibrate results in increased expression of IRF7 mRNA |
CTD |
PMID:25572481 |
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NCBI chr11:612,555...615,950
Ensembl chr11:612,553...615,983
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ITCH |
itchy E3 ubiquitin protein ligase |
multiple interactions decreases expression |
ISO |
PPARA protein affects the reaction [Fenofibrate results in decreased expression of ITCH mRNA] |
CTD |
PMID:21318169 |
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NCBI chr20:34,363,273...34,511,773
Ensembl chr20:34,363,235...34,511,773
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ITFG2 |
integrin alpha FG-GAP repeat containing 2 |
increases expression |
EXP |
Fenofibrate results in increased expression of ITFG2 mRNA |
CTD |
PMID:25596134 |
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NCBI chr12:2,812,668...2,859,791
Ensembl chr12:2,812,622...2,859,791
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ITGB1 |
integrin subunit beta 1 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of ITGB1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr10:32,900,318...32,958,230
Ensembl chr10:32,887,273...33,005,792
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ITGB3 |
integrin subunit beta 3 |
affects expression |
ISO |
Fenofibrate affects the expression of ITGB3 mRNA |
CTD |
PMID:20801182 |
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NCBI chr17:47,253,827...47,313,743
Ensembl chr17:47,253,827...47,313,743
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G |
JUN |
Jun proto-oncogene, AP-1 transcription factor subunit |
multiple interactions |
EXP ISO |
Fenofibrate inhibits the reaction [Glucose results in increased expression of JUN protein] [Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of JUN mRNA; Fenofibrate affects the reaction [[AHR protein affects the susceptibility to AGT protein] which affects the expression of JUN mRNA] |
CTD |
PMID:16600694 PMID:18978307 PMID:31016362 |
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NCBI chr 1:58,780,791...58,784,047
Ensembl chr 1:58,776,845...58,784,048
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G |
KCNK13 |
potassium two pore domain channel subfamily K member 13 |
increases expression |
EXP |
Fenofibrate results in increased expression of KCNK13 mRNA |
CTD |
PMID:25572481 PMID:25596134 |
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NCBI chr14:90,061,994...90,185,853
Ensembl chr14:90,061,994...90,185,853
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KEAP1 |
kelch like ECH associated protein 1 |
multiple interactions |
ISO |
Fenofibrate inhibits the reaction [tyloxapol results in increased expression of KEAP1 protein] |
CTD |
PMID:36905866 |
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NCBI chr19:10,486,125...10,503,356
Ensembl chr19:10,486,125...10,503,558
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G |
KIF22 |
kinesin family member 22 |
increases expression |
ISO |
Fenofibrate results in increased expression of KIF22 mRNA |
CTD |
PMID:32741897 |
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NCBI chr16:29,790,751...29,805,385
Ensembl chr16:29,790,727...29,805,385
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KIFC1 |
kinesin family member C1 |
increases expression |
ISO |
Fenofibrate results in increased expression of KIFC1 mRNA |
CTD |
PMID:32741897 |
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NCBI chr 6:33,391,461...33,409,896
Ensembl chr 6:33,391,823...33,409,896
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G |
KLF10 |
KLF transcription factor 10 |
decreases expression increases expression |
ISO EXP |
Fenofibrate results in decreased expression of KLF10 mRNA Fenofibrate results in increased expression of KLF10 mRNA |
CTD |
PMID:11798191 PMID:25572481 |
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NCBI chr 8:102,648,784...102,655,725
Ensembl chr 8:102,648,784...102,655,725
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G |
KLF11 |
KLF transcription factor 11 |
increases expression |
EXP |
Fenofibrate results in increased expression of KLF11 mRNA |
CTD |
PMID:25572481 |
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NCBI chr 2:10,043,550...10,054,836
Ensembl chr 2:10,042,849...10,054,836
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G |
KRT18 |
keratin 18 |
multiple interactions |
ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of KRT18 protein |
CTD |
PMID:18978307 |
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NCBI chr12:52,948,855...52,952,906
Ensembl chr12:52,948,871...52,952,906
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G |
KRT23 |
keratin 23 |
increases expression |
ISO |
Fenofibrate results in increased expression of KRT23 mRNA |
CTD |
PMID:32741897 |
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NCBI chr17:40,922,700...40,937,646
Ensembl chr17:40,922,700...40,937,646
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G |
KRT8 |
keratin 8 |
multiple interactions |
ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of KRT8 protein |
CTD |
PMID:18978307 |
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NCBI chr12:52,897,191...52,949,860
Ensembl chr12:52,897,187...52,949,954
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KRTAP1-5 |
keratin associated protein 1-5 |
increases expression |
ISO |
Fenofibrate results in increased expression of KRTAP1-5 mRNA |
CTD |
PMID:32741897 |
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NCBI chr17:41,026,026...41,027,208
Ensembl chr17:41,026,026...41,027,208
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G |
LAMA4 |
laminin subunit alpha 4 |
increases expression |
EXP |
Fenofibrate results in increased expression of LAMA4 mRNA |
CTD |
PMID:25572481 |
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NCBI chr 6:112,107,931...112,254,985
Ensembl chr 6:112,107,931...112,254,939
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G |
LARS1 |
leucyl-tRNA synthetase 1 |
increases expression decreases expression |
EXP ISO |
Fenofibrate results in increased expression of LARS1 mRNA Fenofibrate results in decreased expression of LARS1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 5:146,113,034...146,182,650
Ensembl chr 5:146,110,566...146,182,696
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G |
LBH |
LBH regulator of WNT signaling pathway |
increases expression |
EXP |
Fenofibrate results in increased expression of LBH mRNA |
CTD |
PMID:25572481 |
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NCBI chr 2:30,231,534...30,260,028
Ensembl chr 2:30,231,534...30,323,730
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G |
LDHB |
lactate dehydrogenase B |
increases expression |
EXP |
Fenofibrate results in increased expression of LDHB mRNA |
CTD |
PMID:25572481 |
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NCBI chr12:21,635,342...21,657,842
Ensembl chr12:21,635,342...21,757,857
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G |
LEP |
leptin |
multiple interactions |
ISO EXP |
[Fenofibrate co-treated with resveratrol] inhibits the reaction [Fructose results in increased expression of LEP mRNA]; Fenofibrate inhibits the reaction [Fructose results in increased expression of LEP mRNA] Fenofibrate inhibits the reaction [Arsenic Trioxide results in decreased expression of and results in decreased secretion of LEP protein] |
CTD |
PMID:26973390 PMID:32929351 |
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NCBI chr 7:128,241,278...128,257,629
Ensembl chr 7:128,241,278...128,257,629
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G |
LGALS1 |
galectin 1 |
increases expression |
ISO |
Fenofibrate results in increased expression of LGALS1 mRNA |
CTD |
PMID:11798191 |
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NCBI chr22:37,675,636...37,679,802
Ensembl chr22:37,675,636...37,679,802
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G |
LIFR |
LIF receptor subunit alpha |
decreases expression |
ISO |
Fenofibrate results in decreased expression of LIFR mRNA |
CTD |
PMID:11798191 |
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NCBI chr 5:38,474,668...38,608,403
Ensembl chr 5:38,474,668...38,608,354
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G |
LMCD1 |
LIM and cysteine rich domains 1 |
affects expression |
ISO |
Fenofibrate affects the expression of LMCD1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 3:8,501,823...8,574,668
Ensembl chr 3:8,501,807...8,574,668
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G |
LNX1 |
ligand of numb-protein X 1 |
multiple interactions decreases expression |
ISO |
PPARA protein affects the reaction [Fenofibrate results in decreased expression of LNX1 mRNA] |
CTD |
PMID:21318169 |
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NCBI chr 4:53,459,301...53,652,477
Ensembl chr 4:53,459,301...53,701,405
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G |
LPCAT2 |
lysophosphatidylcholine acyltransferase 2 |
increases expression |
EXP |
Fenofibrate results in increased expression of LPCAT2 mRNA |
CTD |
PMID:25572481 |
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NCBI chr16:55,509,072...55,586,666
Ensembl chr16:55,509,072...55,586,666
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G |
LPCAT3 |
lysophosphatidylcholine acyltransferase 3 |
increases expression |
EXP |
Fenofibrate results in increased expression of LPCAT3 mRNA |
CTD |
PMID:25572481 |
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NCBI chr12:6,976,185...7,018,476
Ensembl chr12:6,976,185...7,018,477
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G |
LPL |
lipoprotein lipase |
increases expression multiple interactions increases activity |
ISO EXP |
Fenofibrate results in increased expression of LPL mRNA; Fenofibrate results in increased expression of LPL protein PPARA protein promotes the reaction [Fenofibrate results in increased expression of LPL protein] PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of LPL mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of LPL protein] Fenofibrate inhibits the reaction [Pyrazinamide results in decreased expression of LPL mRNA] Fenofibrate results in increased activity of LPL protein |
CTD |
PMID:8593127 PMID:11798191 PMID:16595124 PMID:24752549 PMID:27071702 |
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NCBI chr 8:19,939,253...19,967,259
Ensembl chr 8:19,901,717...19,967,259
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G |
LRRC31 |
leucine rich repeat containing 31 |
increases expression |
EXP |
Fenofibrate results in increased expression of LRRC31 mRNA |
CTD |
PMID:25572481 |
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NCBI chr 3:169,839,172...169,869,935
Ensembl chr 3:169,839,172...169,869,935
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G |
LRSAM1 |
leucine rich repeat and sterile alpha motif containing 1 |
multiple interactions decreases expression |
ISO |
PPARA protein affects the reaction [Fenofibrate results in decreased expression of LRSAM1 mRNA] |
CTD |
PMID:21318169 |
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NCBI chr 9:127,451,486...127,503,501
Ensembl chr 9:127,451,489...127,503,499
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G |
LSS |
lanosterol synthase |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of LSS mRNA NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of LSS mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of LSS mRNA] |
CTD |
PMID:23063693 |
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NCBI chr21:46,188,446...46,228,774
Ensembl chr21:46,188,141...46,228,824
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G |
LTN1 |
listerin E3 ubiquitin protein ligase 1 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of LTN1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr21:28,928,144...28,992,877
Ensembl chr21:28,928,144...28,992,956
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G |
LY6D |
lymphocyte antigen 6 family member D |
increases expression |
ISO |
Fenofibrate results in increased expression of LY6D mRNA |
CTD |
PMID:17118139 |
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NCBI chr 8:142,784,882...142,786,539
Ensembl chr 8:142,784,882...142,786,539
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G |
LYRM1 |
LYR motif containing 1 |
increases expression |
EXP |
Fenofibrate results in increased expression of LYRM1 mRNA |
CTD |
PMID:25572481 |
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NCBI chr16:20,899,882...20,925,006
Ensembl chr16:20,899,868...20,925,006
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G |
LYZ |
lysozyme |
decreases expression |
ISO |
Fenofibrate results in decreased expression of LYZ2 mRNA |
CTD |
PMID:11798191 |
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NCBI chr12:69,348,381...69,354,234
Ensembl chr12:69,348,381...69,354,234
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G |
MAFG |
MAF bZIP transcription factor G |
decreases expression increases expression |
ISO EXP |
Fenofibrate results in decreased expression of MAFG mRNA Fenofibrate results in increased expression of MAFG mRNA |
CTD |
PMID:25596134 |
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NCBI chr17:81,918,270...81,931,244
Ensembl chr17:81,918,270...81,927,735
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G |
MAN1A1 |
mannosidase alpha class 1A member 1 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of MAN1A mRNA |
CTD |
PMID:16707586 |
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NCBI chr 6:119,177,205...119,350,605
Ensembl chr 6:119,177,205...119,349,761
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G |
MAN1A2 |
mannosidase alpha class 1A member 2 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of MAN1A2 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 1:117,367,449...117,528,872
Ensembl chr 1:117,367,449...117,528,872
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G |
MAOB |
monoamine oxidase B |
multiple interactions |
ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of MAOB mRNA |
CTD |
PMID:18253720 |
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NCBI chr X:43,766,610...43,882,450
Ensembl chr X:43,766,610...43,882,450
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G |
MAP1LC3A |
microtubule associated protein 1 light chain 3 alpha |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of MAP1LC3A mRNA [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of MAP1LC3A mRNA |
CTD |
PMID:21318169 |
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NCBI chr20:34,546,844...34,560,345
Ensembl chr20:34,546,854...34,560,345
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G |
MAP1LC3B |
microtubule associated protein 1 light chain 3 beta |
multiple interactions |
ISO |
Fenofibrate inhibits the reaction [tyloxapol results in increased lipidation of MAP1LC3B protein] |
CTD |
PMID:36905866 |
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NCBI chr16:87,392,336...87,404,774
Ensembl chr16:87,383,953...87,404,779
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G |
MAP3K13 |
mitogen-activated protein kinase kinase kinase 13 |
increases expression |
ISO |
Fenofibrate results in increased expression of MAP3K13 mRNA |
CTD |
PMID:32741897 |
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NCBI chr 3:185,282,961...185,489,094
Ensembl chr 3:185,282,941...185,489,094
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G |
MAT2A |
methionine adenosyltransferase 2A |
decreases expression |
EXP |
Fenofibrate results in decreased expression of MAT2A mRNA |
CTD |
PMID:16569247 |
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NCBI chr 2:85,539,168...85,545,281
Ensembl chr 2:85,539,168...85,545,281
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G |
MC1R |
melanocortin 1 receptor |
decreases expression multiple interactions |
ISO |
Fenofibrate results in decreased expression of MC1R mRNA [Fenofibrate results in decreased expression of MC1R mRNA] which results in decreased chemical synthesis of Melanins |
CTD |
PMID:23872139 |
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NCBI chr16:89,918,862...89,920,972
Ensembl chr16:89,912,119...89,920,973
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G |
MDH2 |
malate dehydrogenase 2 |
increases expression |
EXP |
Fenofibrate results in increased expression of MDH mRNA |
CTD |
PMID:24752549 |
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NCBI chr 7:76,048,106...76,067,508
Ensembl chr 7:76,048,051...76,067,508
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G |
MDM2 |
MDM2 proto-oncogene |
decreases expression |
ISO |
Fenofibrate results in decreased expression of MDM2 mRNA |
CTD |
PMID:25596134 |
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NCBI chr12:68,808,172...68,850,686
Ensembl chr12:68,808,177...68,845,544
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G |
ME1 |
malic enzyme 1 |
affects expression increases expression multiple interactions |
ISO |
Fenofibrate affects the expression of ME1 mRNA Fenofibrate results in increased expression of ME1 mRNA NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ME1 mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ME1 mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ME1 mRNA] |
CTD |
PMID:20801182 PMID:23063693 PMID:25596134 PMID:27071702 |
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NCBI chr 6:83,210,402...83,431,051
Ensembl chr 6:83,210,402...83,431,051
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G |
MERTK |
MER proto-oncogene, tyrosine kinase |
increases expression |
EXP |
Fenofibrate results in increased expression of MERTK mRNA |
CTD |
PMID:25572481 |
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NCBI chr 2:111,898,607...112,029,561
Ensembl chr 2:111,898,607...112,029,561
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G |
MFN2 |
mitofusin 2 |
multiple interactions |
EXP |
Fenofibrate inhibits the reaction [[Fructose co-treated with Palmitic Acid] results in decreased expression of MFN2 protein] |
CTD |
PMID:32730863 |
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NCBI chr 1:11,980,444...12,013,508
Ensembl chr 1:11,980,181...12,015,211
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G |
MFSD2A |
MFSD2 lysolipid transporter A, lysophospholipid |
decreases expression |
EXP |
Fenofibrate results in decreased expression of MFSD2A mRNA |
CTD |
PMID:25572481 |
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NCBI chr 1:39,955,145...39,969,956
Ensembl chr 1:39,955,112...39,969,968
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G |
MGLL |
monoglyceride lipase |
increases expression |
ISO |
Fenofibrate results in increased expression of MGLL mRNA |
CTD |
PMID:11798191 PMID:17118139 PMID:27665778 |
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NCBI chr 3:127,689,066...127,823,185
Ensembl chr 3:127,689,062...128,052,190
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G |
MGMT |
O-6-methylguanine-DNA methyltransferase |
multiple interactions increases expression |
ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of MGMT mRNA Fenofibrate results in increased expression of MGMT mRNA |
CTD |
PMID:17264098 PMID:18253720 |
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NCBI chr10:129,467,241...129,770,983
Ensembl chr10:129,467,190...129,770,983
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G |
MGRN1 |
mahogunin ring finger 1 |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of MGRN1 mRNA [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of MGRN1 mRNA |
CTD |
PMID:21318169 |
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NCBI chr16:4,624,826...4,690,972
Ensembl chr16:4,616,493...4,690,974
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G |
MGST3 |
microsomal glutathione S-transferase 3 |
increases expression |
ISO |
Fenofibrate results in increased expression of MGST3 mRNA |
CTD |
PMID:11798191 |
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NCBI chr 1:165,631,234...165,656,136
Ensembl chr 1:165,631,213...165,661,796
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G |
MITF |
melanocyte inducing transcription factor |
decreases expression |
ISO |
Fenofibrate results in decreased expression of MITF mRNA; Fenofibrate results in decreased expression of MITF protein |
CTD |
PMID:23872139 |
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NCBI chr 3:69,739,464...69,968,332
Ensembl chr 3:69,739,456...69,968,336
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G |
MKI67 |
marker of proliferation Ki-67 |
increases expression |
ISO |
Fenofibrate results in increased expression of MKI67 mRNA; Fenofibrate results in increased expression of MKI67 protein |
CTD |
PMID:17264098 PMID:32741897 |
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NCBI chr10:128,096,659...128,126,423
Ensembl chr10:128,096,659...128,126,423
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G |
MLH1 |
mutL homolog 1 |
multiple interactions increases expression |
ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of MLH1 mRNA; [Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of MLH1 mRNA Fenofibrate results in increased expression of MLH1 mRNA |
CTD |
PMID:17264098 PMID:18253720 PMID:18775883 |
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NCBI chr 3:36,993,466...37,050,846
Ensembl chr 3:36,993,226...37,050,896
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G |
MLYCD |
malonyl-CoA decarboxylase |
multiple interactions |
ISO |
[Fenofibrate co-treated with resveratrol] inhibits the reaction [Fructose results in decreased expression of MLYCD mRNA]; Fenofibrate inhibits the reaction [Fructose results in decreased expression of MLYCD mRNA]; Fenofibrate promotes the reaction [PPARA protein results in increased expression of MLYCD mRNA] |
CTD |
PMID:14641110 PMID:26973390 |
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NCBI chr16:83,899,115...83,927,031
Ensembl chr16:83,899,115...83,951,445
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G |
MMD |
monocyte to macrophage differentiation associated |
increases expression |
EXP |
Fenofibrate results in increased expression of MMD mRNA |
CTD |
PMID:25572481 |
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NCBI chr17:55,392,622...55,421,835
Ensembl chr17:55,392,622...55,421,924
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G |
MMP1 |
matrix metallopeptidase 1 |
decreases expression |
EXP |
Fenofibrate results in decreased expression of MMP1 protein |
CTD |
PMID:25545733 |
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NCBI chr11:102,789,919...102,798,160
Ensembl chr11:102,789,401...102,798,160
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G |
MMP19 |
matrix metallopeptidase 19 |
increases expression |
ISO |
Fenofibrate results in increased expression of MMP19 mRNA |
CTD |
PMID:25596134 |
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NCBI chr12:55,835,433...55,842,936
Ensembl chr12:55,835,433...55,842,966
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G |
MMP2 |
matrix metallopeptidase 2 |
decreases expression |
EXP |
Fenofibrate results in decreased expression of MMP2 protein |
CTD |
PMID:25545733 |
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NCBI chr16:55,478,830...55,506,691
Ensembl chr16:55,389,700...55,506,691
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G |
MMP7 |
matrix metallopeptidase 7 |
decreases expression |
EXP |
Fenofibrate results in decreased expression of MMP7 protein |
CTD |
PMID:25545733 |
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NCBI chr11:102,520,508...102,530,747
Ensembl chr11:102,520,508...102,530,750
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G |
MMP9 |
matrix metallopeptidase 9 |
multiple interactions decreases expression |
EXP |
Fenofibrate inhibits the reaction [Dinoprostone results in increased expression of MMP9 mRNA]; Fenofibrate inhibits the reaction [Dinoprostone results in increased secretion of MMP9 protein]; Fenofibrate inhibits the reaction [Lipopolysaccharides results in increased secretion of MMP9 protein] Fenofibrate results in decreased expression of MMP9 protein |
CTD |
PMID:19880272 PMID:21075133 PMID:25545733 |
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NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561
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G |
MRAP |
melanocortin 2 receptor accessory protein |
increases expression |
ISO |
Fenofibrate results in increased expression of MRAP mRNA |
CTD |
PMID:11798191 |
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NCBI chr21:32,291,813...32,314,784
Ensembl chr21:32,291,813...32,314,784
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G |
MS4A10 |
membrane spanning 4-domains A10 |
decreases expression |
EXP |
Fenofibrate results in decreased expression of MS4A10 mRNA |
CTD |
PMID:25572481 |
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NCBI chr11:60,785,333...60,801,305
Ensembl chr11:60,785,333...60,801,305
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G |
MSC |
musculin |
decreases expression |
ISO |
Fenofibrate results in decreased expression of MSC mRNA |
CTD |
PMID:25596134 |
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NCBI chr 8:71,841,560...71,844,412
Ensembl chr 8:71,841,560...71,844,412
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G |
MSMO1 |
methylsterol monooxygenase 1 |
affects expression |
ISO |
Fenofibrate affects the expression of MSMO1 mRNA |
CTD |
PMID:20801182 |
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NCBI chr 4:165,327,669...165,343,164
Ensembl chr 4:165,327,667...165,343,164
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G |
MTTP |
microsomal triglyceride transfer protein |
increases expression |
ISO |
Fenofibrate results in increased expression of MTTP mRNA |
CTD |
PMID:32741897 |
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NCBI chr 4:99,564,130...99,623,997
Ensembl chr 4:99,564,081...99,623,997
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G |
MYC |
MYC proto-oncogene, bHLH transcription factor |
multiple interactions increases expression |
ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of MYC mRNA Fenofibrate results in increased expression of MYC mRNA |
CTD |
PMID:18978307 PMID:32741897 |
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NCBI chr 8:127,735,434...127,742,951
Ensembl chr 8:127,735,434...127,742,951
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G |
MYLK |
myosin light chain kinase |
decreases expression |
EXP |
Fenofibrate results in decreased expression of MYLK mRNA |
CTD |
PMID:25572481 |
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NCBI chr 3:123,610,049...123,884,332
Ensembl chr 3:123,610,049...123,884,332
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G |
N4BP2L1 |
NEDD4 binding protein 2 like 1 |
increases expression |
EXP |
Fenofibrate results in increased expression of N4BP2L1 mRNA |
CTD |
PMID:25572481 |
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NCBI chr13:32,400,723...32,429,615
Ensembl chr13:32,400,723...32,428,311
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G |
NACC1 |
nucleus accumbens associated 1 |
increases expression |
ISO |
Fenofibrate results in increased expression of NACC1 mRNA |
CTD |
PMID:17264098 |
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NCBI chr19:13,116,852...13,141,147
Ensembl chr19:13,116,862...13,141,147
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G |
NAMPT |
nicotinamide phosphoribosyltransferase |
increases expression |
ISO |
Fenofibrate results in increased expression of NAMPT mRNA |
CTD |
PMID:25596134 |
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NCBI chr 7:106,248,298...106,285,888
Ensembl chr 7:106,248,298...106,285,966
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G |
NARS1 |
asparaginyl-tRNA synthetase 1 |
affects expression |
ISO |
Fenofibrate affects the expression of NARS1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr18:57,600,656...57,621,836
Ensembl chr18:57,600,656...57,622,213
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G |
NBN |
nibrin |
multiple interactions increases expression |
ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of NBN mRNA Fenofibrate results in increased expression of NBN mRNA |
CTD |
PMID:17264098 PMID:18253720 PMID:18775883 |
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NCBI chr 8:89,933,331...89,984,667
Ensembl chr 8:89,924,515...90,003,228
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G |
NCEH1 |
neutral cholesterol ester hydrolase 1 |
increases expression |
ISO |
Fenofibrate results in increased expression of NCEH1 mRNA |
CTD |
PMID:27665778 |
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NCBI chr 3:172,630,249...172,711,067
Ensembl chr 3:172,630,249...172,711,218
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G |
NDUFAB1 |
NADH:ubiquinone oxidoreductase subunit AB1 |
increases expression |
ISO |
Fenofibrate results in increased expression of NDUFAB1 mRNA |
CTD |
PMID:11798191 |
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NCBI chr16:23,581,014...23,596,316
Ensembl chr16:23,581,014...23,596,316
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G |
NEAT1 |
nuclear paraspeckle assembly transcript 1 |
increases expression |
EXP |
Fenofibrate results in increased expression of NEAT1 mRNA; Fenofibrate results in increased expression of NEAT1 mRNA alternative form |
CTD |
PMID:31311324 |
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NCBI chr11:65,422,798...65,445,540
Ensembl chr11:65,422,278...65,445,540
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G |
NEDD4 |
NEDD4 E3 ubiquitin protein ligase |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of NEDD4 mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of NEDD4 mRNA] |
CTD |
PMID:21318169 |
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NCBI chr15:55,826,917...55,993,612
Ensembl chr15:55,826,922...55,993,660
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G |
NEDD9 |
neural precursor cell expressed, developmentally down-regulated 9 |
decreases expression |
EXP ISO |
Fenofibrate results in decreased expression of NEDD9 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 6:11,183,298...11,382,348
Ensembl chr 6:11,183,298...11,382,348
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G |
NFATC4 |
nuclear factor of activated T cells 4 |
multiple interactions |
ISO |
EDN1 protein promotes the reaction [Fenofibrate promotes the reaction [NFATC4 protein binds to PPARA protein]]; Fenofibrate inhibits the reaction [EDN1 protein promotes the reaction [NFATC4 protein binds to GATA4 protein]]; Fenofibrate inhibits the reaction [EDN1 protein promotes the reaction [NFATC4 protein binds to NPPB promoter]]; Fenofibrate promotes the reaction [NFATC4 protein binds to PPARA protein]; PPARA mutant form inhibits the reaction [Fenofibrate inhibits the reaction [EDN1 protein promotes the reaction [NFATC4 protein binds to GATA4 protein]]] |
CTD |
PMID:22198280 |
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NCBI chr14:24,366,911...24,379,604
Ensembl chr14:24,365,673...24,379,604
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G |
NFE2L2 |
NFE2 like bZIP transcription factor 2 |
multiple interactions increases activity decreases expression affects activity |
ISO EXP |
[Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of NFE2L2 protein Fenofibrate inhibits the reaction [[Fructose co-treated with Palmitic Acid] results in decreased expression of NFE2L2 protein] Fenofibrate inhibits the reaction [triptolide results in increased expression of NFE2L2 mRNA]; Fenofibrate inhibits the reaction [triptolide results in increased expression of NFE2L2 protein] Fenofibrate results in increased activity of NFE2L2 protein Fenofibrate results in decreased expression of NFE2L2 mRNA Fenofibrate affects the activity of NFE2L2 protein |
CTD |
PMID:18775883 PMID:25596134 PMID:30114225 PMID:30203046 PMID:31241159 PMID:32730863 More...
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NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756
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G |
NFKB1 |
nuclear factor kappa B subunit 1 |
multiple interactions affects localization |
EXP |
Fenofibrate inhibits the reaction [ALB protein modified form results in increased expression of NFKB1 protein] Fenofibrate affects the localization of NFKB1 protein |
CTD |
PMID:20580385 PMID:25545733 |
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NCBI chr 4:102,501,359...102,617,302
Ensembl chr 4:102,501,330...102,617,302
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G |
NFKBIA |
NFKB inhibitor alpha |
multiple interactions decreases expression |
EXP |
Fenofibrate inhibits the reaction [ALB protein modified form results in increased degradation of NFKBIA protein] Fenofibrate results in decreased expression of NFKBIA protein modified form |
CTD |
PMID:20580385 PMID:25545733 |
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NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,079...35,404,749
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G |
NFKBIB |
NFKB inhibitor beta |
multiple interactions |
ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of NFKBIB mRNA; [Fenofibrate co-treated with Sodium Glutamate] results in increased expression of NFKBIB mRNA |
CTD |
PMID:18253720 PMID:21999347 |
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NCBI chr19:38,899,666...38,908,889
Ensembl chr19:38,899,700...38,908,893
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G |
NIM1K |
NIM1 serine/threonine protein kinase |
increases expression |
ISO |
Fenofibrate results in increased expression of NIM1K mRNA |
CTD |
PMID:32741897 |
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NCBI chr 5:43,192,225...43,280,850
Ensembl chr 5:43,192,071...43,280,850
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G |
NINJ1 |
ninjurin 1 |
affects expression |
ISO |
Fenofibrate affects the expression of NINJ1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 9:93,121,496...93,134,251
Ensembl chr 9:93,121,496...93,134,251
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G |
NLRP3 |
NLR family pyrin domain containing 3 |
multiple interactions |
ISO |
Fenofibrate inhibits the reaction [Cyclophosphamide results in increased expression of NLRP3 protein] |
CTD |
PMID:38278497 |
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NCBI chr 1:247,416,077...247,448,817
Ensembl chr 1:247,332,331...247,449,108
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G |
NMUR1 |
neuromedin U receptor 1 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of NMUR1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 2:231,518,455...231,530,445
Ensembl chr 2:231,523,187...231,530,445
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G |
NNMT |
nicotinamide N-methyltransferase |
multiple interactions |
ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of NNMT mRNA |
CTD |
PMID:18253720 |
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NCBI chr11:114,257,806...114,313,536
Ensembl chr11:114,257,787...114,313,536
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G |
NOS2 |
nitric oxide synthase 2 |
multiple interactions |
ISO |
Fenofibrate inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA] [Fenofibrate co-treated with Sodium Glutamate] results in increased expression of NOS2 mRNA; [Fenofibrate co-treated with Sodium Glutamate] results in increased expression of NOS2 protein |
CTD |
PMID:21300114 PMID:21999347 |
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NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529
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G |
NOS3 |
nitric oxide synthase 3 |
multiple interactions increases phosphorylation increases activity |
EXP |
dorsomorphin inhibits the reaction [Fenofibrate results in increased activity of NOS3 protein]; Fenofibrate inhibits the reaction [Wortmannin results in decreased phosphorylation of NOS3 protein]; PRKAA1 protein affects the reaction [Fenofibrate results in increased activity of NOS3 protein] Fenofibrate results in increased phosphorylation of NOS3 protein |
CTD |
PMID:16442496 PMID:20580385 |
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NCBI chr 7:150,991,017...151,014,588
Ensembl chr 7:150,991,017...151,014,588
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G |
NOTCH1 |
notch receptor 1 |
multiple interactions |
ISO |
Fenofibrate inhibits the reaction [triptolide results in increased expression of NOTCH1 mRNA] |
CTD |
PMID:31241159 |
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NCBI chr 9:136,494,433...136,546,048
Ensembl chr 9:136,494,433...136,546,048
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G |
NOTCH3 |
notch receptor 3 |
multiple interactions |
ISO |
Fenofibrate inhibits the reaction [triptolide results in increased expression of NOTCH3 mRNA]; Fenofibrate inhibits the reaction [triptolide results in increased expression of NOTCH3 protein] |
CTD |
PMID:31241159 |
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NCBI chr19:15,159,038...15,200,995
Ensembl chr19:15,159,038...15,200,995
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G |
NPPA |
natriuretic peptide A |
multiple interactions |
ISO |
Fenofibrate inhibits the reaction [Doxorubicin results in decreased expression of NPPA mRNA] |
CTD |
PMID:17531194 |
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NCBI chr 1:11,845,709...11,847,783
Ensembl chr 1:11,845,709...11,848,345
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G |
NPPB |
natriuretic peptide B |
multiple interactions |
ISO |
Fenofibrate inhibits the reaction [EDN1 protein promotes the reaction [NFATC4 protein binds to NPPB promoter]]; Fenofibrate inhibits the reaction [EDN1 protein results in increased expression of NPPB mRNA]; PPARA mutant form inhibits the reaction [Fenofibrate inhibits the reaction [EDN1 protein results in increased expression of NPPB mRNA]] |
CTD |
PMID:22198280 |
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NCBI chr 1:11,857,464...11,858,945
Ensembl chr 1:11,857,464...11,858,945
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G |
NR0B2 |
nuclear receptor subfamily 0 group B member 2 |
multiple interactions increases expression |
EXP ISO |
Dactinomycin inhibits the reaction [Fenofibrate results in increased expression of NR0B2 mRNA]; dorsomorphin inhibits the reaction [Fenofibrate results in increased expression of NR0B2 mRNA]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [NR4A1 protein results in increased expression of SERPINE1 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [SMAD3 protein results in increased expression of SERPINE1 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [SMAD4 protein results in increased expression of SERPINE1 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of SERPINE1 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [TNF protein results in increased expression of SERPINE1 mRNA]]; pyrazolanthrone inhibits the reaction [Fenofibrate results in increased expression of NR0B2 mRNA] [Methionine deficiency co-treated with Choline deficiency co-treated with Fenofibrate] results in increased expression of NR0B2 mRNA; NR0B2 protein inhibits the reaction [Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]]; NR0B2 protein inhibits the reaction [Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of IL6 mRNA]]; NR0B2 protein inhibits the reaction [Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of SERPINE1 mRNA]]; NR0B2 protein inhibits the reaction [Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of TIMP1 mRNA]]; NR0B2 protein promotes the reaction [[Methionine deficiency co-treated with Choline deficiency co-treated with Fenofibrate] results in increased expression of CYP4A14 mRNA]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of COL1A1 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of FAS mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of IL6 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of SERPINE1 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of SREBF1 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of TGFB1 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of TIMP1 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of TNF mRNA]] Fenofibrate results in increased expression of NR0B2 mRNA; Fenofibrate results in increased expression of NR0B2 protein |
CTD |
PMID:19593819 |
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NCBI chr 1:26,911,489...26,913,975
Ensembl chr 1:26,911,489...26,913,975
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G |
NR1H2 |
nuclear receptor subfamily 1 group H member 2 |
increases expression multiple interactions |
EXP ISO |
Fenofibrate results in increased expression of NR1H2 mRNA NR1H2 gene mutant form affects the reaction [Fenofibrate results in increased expression of ACACB mRNA]; NR1H2 gene mutant form affects the reaction [Fenofibrate results in increased expression of SCD1 mRNA]; NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACACA mRNA]; NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACOX1 mRNA]; NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of CYP4A10 mRNA]; NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of CYP4A14 mRNA]; NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ELOVL6 mRNA]; NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of FASN mRNA]; NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of FDFT1 mRNA]; NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of HMGCR mRNA]; NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of LSS mRNA]; NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ME1 mRNA]; NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of PPARA mRNA]; NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of SCD2 mRNA]; NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of SQLE mRNA]; NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of SREBF1 mRNA] |
CTD |
PMID:19201410 PMID:23063693 |
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NCBI chr19:50,376,457...50,383,388
Ensembl chr19:50,329,653...50,383,388
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G |
NR1H3 |
nuclear receptor subfamily 1 group H member 3 |
increases expression multiple interactions affects response to substance |
EXP ISO |
Fenofibrate results in increased expression of NR1H3 mRNA NR1H3 gene mutant form affects the reaction [Fenofibrate results in increased expression of ACACB mRNA]; NR1H3 gene mutant form affects the reaction [Fenofibrate results in increased expression of SCD1 mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACACA mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACOX1 mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of CYP4A10 mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of CYP4A14 mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ELOVL6 mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of FASN mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of FDFT1 mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of HMGCR mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of LSS mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ME1 mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of PPARA mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of SCD2 mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of SQLE mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of SREBF1 mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of NR1H3 mRNA] NR1H3 protein affects the susceptibility to Fenofibrate [Oleic Acid co-treated with Fenofibrate] affects the expression of NR1H3 mRNA; NR1H3 protein affects the reaction [Fenofibrate results in increased expression of PPARA mRNA] |
CTD |
PMID:19201410 PMID:23063693 PMID:24534255 PMID:25949234 |
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NCBI chr11:47,248,300...47,269,033
Ensembl chr11:47,248,300...47,269,033
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G |
NR1H4 |
nuclear receptor subfamily 1 group H member 4 |
multiple interactions increases expression |
EXP ISO |
[Oleic Acid co-treated with Fenofibrate] results in decreased expression of NR1H4 mRNA fenofibrate increases expression of Nr1h4 mRNA in steatotic liver |
CTD RGD |
PMID:24534255 PMID:30257410 |
RGD:15090799 |
NCBI chr12:100,473,866...100,564,414
Ensembl chr12:100,473,708...100,564,414
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G |
NR1I2 |
nuclear receptor subfamily 1 group I member 2 |
multiple interactions |
EXP |
Fenofibrate binds to and results in increased activity of NR1I2 protein |
CTD |
PMID:20024649 |
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NCBI chr 3:119,782,101...119,818,487
Ensembl chr 3:119,780,484...119,818,487
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G |
NR1I3 |
nuclear receptor subfamily 1 group I member 3 |
affects localization increases activity multiple interactions increases expression |
ISO EXP |
Fenofibrate affects the localization of NR1I3 protein Fenofibrate results in increased activity of NR1I3 protein [Oleic Acid co-treated with Fenofibrate] results in increased expression of NR1I3 mRNA; Fenofibrate binds to and results in increased activity of NR1I3 protein alternative form Fenofibrate results in increased expression of NR1I3 mRNA |
CTD |
PMID:17962186 PMID:19118567 PMID:24534255 PMID:30203046 PMID:31312845 PMID:32741897 More...
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NCBI chr 1:161,229,669...161,238,203
Ensembl chr 1:161,229,666...161,238,244
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G |
NR4A1 |
nuclear receptor subfamily 4 group A member 1 |
multiple interactions |
EXP |
Fenofibrate inhibits the reaction [NR4A1 protein results in increased expression of SERPINE1 mRNA]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [NR4A1 protein results in increased expression of SERPINE1 mRNA]] |
CTD |
PMID:19593819 |
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NCBI chr12:52,022,832...52,059,503
Ensembl chr12:52,022,832...52,059,507
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G |
NREP |
neuronal regeneration related protein |
decreases expression |
EXP |
Fenofibrate results in decreased expression of NREP mRNA |
CTD |
PMID:25596134 |
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NCBI chr 5:111,728,802...111,976,932
Ensembl chr 5:111,662,621...111,997,464
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G |
NSDHL |
NAD(P) dependent steroid dehydrogenase-like |
increases expression |
ISO |
Fenofibrate results in increased expression of NSDHL mRNA |
CTD |
PMID:11798191 |
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NCBI chr X:152,831,063...152,869,729
Ensembl chr X:152,830,967...152,869,729
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G |
NTPCR |
nucleoside-triphosphatase, cancer-related |
affects expression |
ISO |
Fenofibrate affects the expression of NTPCR mRNA |
CTD |
PMID:25596134 |
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NCBI chr 1:232,950,611...232,983,882
Ensembl chr 1:232,950,605...232,983,882
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G |
NUAK1 |
NUAK family kinase 1 |
decreases expression |
EXP |
Fenofibrate results in decreased expression of NUAK1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr12:106,063,345...106,138,954
Ensembl chr12:106,063,345...106,138,954
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G |
OASL |
2'-5'-oligoadenylate synthetase like |
increases expression |
EXP |
Fenofibrate results in increased expression of OASL mRNA |
CTD |
PMID:25572481 |
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NCBI chr12:121,017,761...121,039,246
Ensembl chr12:121,017,763...121,039,246
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G |
OPA1 |
OPA1 mitochondrial dynamin like GTPase |
multiple interactions |
EXP |
Fenofibrate inhibits the reaction [[Fructose co-treated with Palmitic Acid] results in decreased expression of OPA1 protein] |
CTD |
PMID:32730863 |
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NCBI chr 3:193,593,208...193,697,811
Ensembl chr 3:193,593,144...193,697,811
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G |
OR7E14P |
olfactory receptor family 7 subfamily E member 14 pseudogene |
increases expression |
EXP |
Fenofibrate results in increased expression of OR7E14P mRNA |
CTD |
PMID:25572481 |
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NCBI chr11:17,051,886...17,053,044
Ensembl chr11:17,052,025...17,053,024
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G |
ORAI3 |
ORAI calcium release-activated calcium modulator 3 |
decreases expression |
EXP |
Fenofibrate results in decreased expression of ORAI3 mRNA |
CTD |
PMID:25596134 |
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NCBI chr16:30,949,068...30,954,938
Ensembl chr16:30,949,068...30,956,461
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G |
ORM2 |
orosomucoid 2 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of ORM2 mRNA |
CTD |
PMID:11798191 |
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NCBI chr 9:114,329,869...114,333,251
Ensembl chr 9:114,329,869...114,333,251
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G |
OSGIN1 |
oxidative stress induced growth inhibitor 1 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of OSGIN1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr16:83,953,240...83,966,332
Ensembl chr16:83,931,311...83,966,332
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G |
P4HA1 |
prolyl 4-hydroxylase subunit alpha 1 |
affects expression |
ISO |
Fenofibrate affects the expression of P4HA1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr10:73,007,217...73,096,866
Ensembl chr10:73,007,217...73,096,974
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G |
P4HB |
prolyl 4-hydroxylase subunit beta |
affects expression |
ISO |
Fenofibrate affects the expression of P4HB mRNA |
CTD |
PMID:20801182 |
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NCBI chr17:81,843,166...81,860,535
Ensembl chr17:81,843,159...81,860,856
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G |
PANK1 |
pantothenate kinase 1 |
increases expression |
ISO EXP |
Fenofibrate results in increased expression of PANK1 mRNA |
CTD |
PMID:16707586 PMID:25572481 PMID:25596134 |
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NCBI chr10:89,579,495...89,645,242
Ensembl chr10:89,579,497...89,645,242
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G |
PBK |
PDZ binding kinase |
increases expression |
ISO |
Fenofibrate results in increased expression of PBK mRNA |
CTD |
PMID:32741897 |
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NCBI chr 8:27,809,624...27,837,817
Ensembl chr 8:27,809,624...27,838,082
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G |
PCK1 |
phosphoenolpyruvate carboxykinase 1 |
increases expression |
EXP |
Fenofibrate results in increased expression of PCK1 mRNA |
CTD |
PMID:25572481 |
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NCBI chr20:57,561,110...57,568,121
Ensembl chr20:57,561,080...57,568,121
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G |
PCK2 |
phosphoenolpyruvate carboxykinase 2, mitochondrial |
increases expression |
EXP |
Fenofibrate results in increased expression of PCK2 mRNA |
CTD |
PMID:16569247 PMID:24752549 |
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NCBI chr14:24,094,171...24,104,125
Ensembl chr14:24,094,053...24,110,598
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G |
PCNA |
proliferating cell nuclear antigen |
multiple interactions increases expression |
ISO EXP |
[Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of PCNA protein Fenofibrate results in increased expression of PCNA protein ESR1 protein inhibits the reaction [Fenofibrate results in increased expression of PCNA protein]; Estradiol inhibits the reaction [Fenofibrate results in increased expression of PCNA protein] |
CTD |
PMID:18978307 PMID:29134746 |
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NCBI chr20:5,114,953...5,126,622
Ensembl chr20:5,114,953...5,126,626
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G |
PCSK9 |
proprotein convertase subtilisin/kexin type 9 |
increases expression |
EXP |
Fenofibrate results in increased expression of PCSK9 protein |
CTD |
PMID:21411093 |
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NCBI chr 1:55,039,548...55,064,852
Ensembl chr 1:55,039,445...55,064,852
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G |
PDIA5 |
protein disulfide isomerase family A member 5 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of PDIA5 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 3:123,067,025...123,162,104
Ensembl chr 3:123,067,025...123,225,227
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G |
PDK1 |
pyruvate dehydrogenase kinase 1 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of PDK1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 2:172,555,373...172,724,312
Ensembl chr 2:172,555,373...172,608,669
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G |
PDK4 |
pyruvate dehydrogenase kinase 4 |
increases expression |
ISO EXP |
Fenofibrate results in increased expression of PDK4 mRNA |
CTD |
PMID:17118139 PMID:19395589 PMID:25572481 PMID:25596134 PMID:27665778 PMID:32741897 More...
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NCBI chr 7:95,583,499...95,596,516
Ensembl chr 7:95,583,499...95,596,516
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G |
PDLIM1 |
PDZ and LIM domain 1 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of PDLIM1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr10:95,237,572...95,291,003
Ensembl chr10:95,237,572...95,291,012
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G |
PDRG1 |
p53 and DNA damage regulated 1 |
multiple interactions decreases expression |
ISO |
PPARA protein affects the reaction [Fenofibrate results in decreased expression of PDRG1 mRNA] |
CTD |
PMID:21318169 |
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NCBI chr20:31,944,337...31,952,046
Ensembl chr20:31,944,337...31,952,046
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G |
PEMT |
phosphatidylethanolamine N-methyltransferase |
increases expression |
EXP |
Fenofibrate results in increased expression of PEMT mRNA |
CTD |
PMID:25572481 |
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NCBI chr17:17,505,563...17,592,142
Ensembl chr17:17,505,563...17,591,708
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G |
PEX11A |
peroxisomal biogenesis factor 11 alpha |
affects expression increases expression |
ISO EXP |
Fenofibrate affects the expression of PEX11A mRNA Fenofibrate results in increased expression of PEX11A mRNA |
CTD |
PMID:20801182 PMID:25572481 PMID:27665778 PMID:32741897 |
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NCBI chr15:89,681,535...89,690,754
Ensembl chr15:89,677,764...89,690,783
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G |
PGM1 |
phosphoglucomutase 1 |
increases expression |
EXP |
Fenofibrate results in increased expression of PGM1 mRNA |
CTD |
PMID:24752549 |
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NCBI chr 1:63,593,411...63,660,245
Ensembl chr 1:63,593,411...63,660,245
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G |
PHGDH |
phosphoglycerate dehydrogenase |
increases expression |
ISO EXP |
Fenofibrate results in increased expression of PHGDH mRNA |
CTD |
PMID:25596134 |
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NCBI chr 1:119,711,934...119,744,215
Ensembl chr 1:119,648,411...119,744,218
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G |
PHLDA1 |
pleckstrin homology like domain family A member 1 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of PHLDA1 mRNA |
CTD |
PMID:11798191 |
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NCBI chr12:76,025,447...76,031,776
Ensembl chr12:76,025,447...76,031,776
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G |
PHLDA3 |
pleckstrin homology like domain family A member 3 |
affects expression |
ISO |
Fenofibrate affects the expression of PHLDA3 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 1:201,464,278...201,469,188
Ensembl chr 1:201,464,278...201,469,237
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G |
PIK3C2G |
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma |
decreases expression |
ISO |
Fenofibrate results in decreased expression of PIK3C2G mRNA |
CTD |
PMID:16707586 |
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NCBI chr12:18,242,961...18,726,817
Ensembl chr12:18,242,961...18,648,416
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G |
PIR |
pirin |
decreases expression |
ISO |
Fenofibrate results in decreased expression of PIR mRNA |
CTD |
PMID:25596134 |
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NCBI chr X:15,384,799...15,493,333
Ensembl chr X:15,384,799...15,493,564
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G |
PJA2 |
praja ring finger ubiquitin ligase 2 |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of PJA2 mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of PJA2 mRNA] |
CTD |
PMID:21318169 |
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NCBI chr 5:109,334,722...109,409,974
Ensembl chr 5:109,334,713...109,409,974
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G |
PKIB |
cAMP-dependent protein kinase inhibitor beta |
increases expression |
EXP |
Fenofibrate results in increased expression of PKIB mRNA |
CTD |
PMID:25572481 |
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NCBI chr 6:122,471,921...122,726,373
Ensembl chr 6:122,471,917...122,726,373
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G |
PKLR |
pyruvate kinase L/R |
decreases expression |
EXP |
Fenofibrate results in decreased expression of PKLR mRNA |
CTD |
PMID:25572481 |
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NCBI chr 1:155,289,293...155,308,654
Ensembl chr 1:155,289,293...155,301,438
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G |
PLA1A |
phospholipase A1 member A |
increases expression |
EXP |
Fenofibrate results in increased expression of PLA1A mRNA |
CTD |
PMID:25572481 |
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NCBI chr 3:119,597,885...119,629,811
Ensembl chr 3:119,597,875...119,629,811
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G |
PLA2G7 |
phospholipase A2 group VII |
decreases activity multiple interactions |
EXP |
Fenofibrate results in decreased activity of PLA2G7 protein [orlistat co-treated with Fenofibrate] results in decreased activity of PLA2G7 protein |
CTD |
PMID:16911813 |
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NCBI chr 6:46,704,201...46,735,721
Ensembl chr 6:46,704,201...46,735,693
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G |
PLCXD3 |
phosphatidylinositol specific phospholipase C X domain containing 3 |
decreases expression |
EXP |
Fenofibrate results in decreased expression of PLCXD3 mRNA |
CTD |
PMID:25572481 |
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NCBI chr 5:41,306,952...41,510,601
Ensembl chr 5:41,306,952...41,510,601
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G |
PLIN1 |
perilipin 1 |
increases expression |
EXP |
Fenofibrate results in increased expression of PLIN1 mRNA |
CTD |
PMID:25572481 |
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NCBI chr15:89,664,367...89,679,367
Ensembl chr15:89,664,367...89,679,427
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G |
PLIN2 |
perilipin 2 |
increases expression multiple interactions |
EXP ISO |
Fenofibrate results in increased expression of PLIN2 mRNA Fenofibrate promotes the reaction [Oleic Acid results in increased expression of PLIN2 mRNA] |
CTD |
PMID:24534255 PMID:25572481 PMID:25596134 PMID:27665778 |
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NCBI chr 9:19,108,388...19,127,492
Ensembl chr 9:19,108,375...19,149,290
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G |
PLIN4 |
perilipin 4 |
increases expression |
EXP |
Fenofibrate results in increased expression of PLIN4 mRNA |
CTD |
PMID:25572481 |
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NCBI chr19:4,502,192...4,518,486
Ensembl chr19:4,502,192...4,518,486
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G |
PLIN5 |
perilipin 5 |
increases expression |
ISO |
Fenofibrate results in increased expression of PLIN5 mRNA |
CTD |
PMID:32741897 |
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NCBI chr19:4,522,531...4,535,224
Ensembl chr19:4,522,531...4,535,224
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G |
PLTP |
phospholipid transfer protein |
increases expression |
ISO |
Fenofibrate results in increased expression of PLTP mRNA |
CTD |
PMID:11798191 |
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NCBI chr20:45,898,620...45,912,155
Ensembl chr20:45,898,621...45,912,155
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G |
PMEPA1 |
prostate transmembrane protein, androgen induced 1 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of PMEPA1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr20:57,648,396...57,711,472
Ensembl chr20:57,648,392...57,711,536
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G |
PML |
PML nuclear body scaffold |
multiple interactions |
EXP |
Fenofibrate promotes the reaction [Arsenic Trioxide results in decreased expression of PML protein mutant form] |
CTD |
PMID:32929351 |
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NCBI chr15:73,994,716...74,047,827
Ensembl chr15:73,994,673...74,047,827
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G |
PODXL |
podocalyxin like |
decreases expression |
EXP ISO |
Fenofibrate results in decreased expression of PODXL mRNA |
CTD |
PMID:25596134 |
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NCBI chr 7:131,500,271...131,556,628
Ensembl chr 7:131,500,262...131,558,217
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G |
PON1 |
paraoxonase 1 |
increases expression |
EXP |
Fenofibrate results in increased expression of PON1 protein |
CTD |
PMID:16123850 |
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NCBI chr 7:95,297,676...95,324,532
Ensembl chr 7:95,297,676...95,324,532
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G |
POR |
cytochrome p450 oxidoreductase |
increases expression |
ISO EXP |
Fenofibrate results in increased expression of POR mRNA |
CTD |
PMID:16707586 PMID:25572481 |
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NCBI chr 7:75,915,155...75,986,855
Ensembl chr 7:75,899,200...75,986,855
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G |
PPAN |
peter pan homolog |
affects expression |
ISO |
Fenofibrate affects the expression of PPAN mRNA |
CTD |
PMID:25596134 |
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NCBI chr19:10,106,223...10,112,012
Ensembl chr19:10,106,362...10,112,012
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G |
PPARA |
peroxisome proliferator activated receptor alpha |
decreases expression multiple interactions decreases response to substance increases activity increases response to substance increases expression affects response to substance |
EXP ISO |
Fenofibrate results in decreased expression of PPARA mRNA fenofibrate co-treated with fructose diet decreases expression of ppara mRNA in liver PPARA gene mutant form results in decreased susceptibility to Fenofibrate Fenofibrate results in increased activity of PPARA protein PPARA protein results in increased susceptibility to Fenofibrate [Fenofibrate co-treated with Fatty Acids, Nonesterified] results in increased expression of PPARA mRNA; ESR1 protein inhibits the reaction [Estradiol inhibits the reaction [Fenofibrate inhibits the reaction [ESR1 protein binds to PPARA protein]]]; ESR1 protein inhibits the reaction [Fenofibrate inhibits the reaction [ESR1 protein binds to PPARA protein]]; Estradiol inhibits the reaction [ESR1 protein inhibits the reaction [Fenofibrate inhibits the reaction [ESR1 protein binds to PPARA protein]]]; Estradiol inhibits the reaction [Fenofibrate inhibits the reaction [ESR1 protein binds to PPARA protein]]; Fenofibrate binds to and results in increased activity of PPARA protein; Fenofibrate inhibits the reaction [ESR1 protein binds to PPARA protein]; Fenofibrate inhibits the reaction [Fatty Acids, Nonesterified results in decreased expression of PPARA mRNA]; Fenofibrate inhibits the reaction [Fatty Acids, Nonesterified results in decreased expression of PPARA protein]; NR1H3 protein affects the reaction [Fenofibrate results in increased expression of PPARA mRNA]; PPARA protein inhibits the reaction [Fenofibrate results in decreased expression of APOA1 mRNA]; PPARA protein promotes the reaction [Fenofibrate results in increased expression of ACOX1 protein]; PPARA protein promotes the reaction [Fenofibrate results in increased expression of ACSL1 protein]; PPARA protein promotes the reaction [Fenofibrate results in increased expression of LPL protein]; PPARA protein promotes the reaction [Fenofibrate results in increased expression of SLC27A4 protein]; PPARA protein promotes the reaction [Fenofibrate results in increased expression of UCP2 protein] [Fenofibrate binds to and results in increased activity of PPARA protein] which affects the abundance of Fatty Acids, Nonesterified; [Fenofibrate binds to and results in increased activity of PPARA protein] which affects the abundance of Triglycerides; [Fenofibrate results in increased activity of PPARA protein] which results in decreased abundance of Adenosine Triphosphate; [Fenofibrate results in increased activity of PPARA protein] which results in increased expression of TRIB3 mRNA; [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of ASB6 mRNA; [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of BRCC3 mRNA; [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of DNAJC14 mRNA; [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of DNAJC19 mRNA; [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of DNAJC2 mRNA; [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of FKBP15 mRNA; [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of HECTD1 mRNA; [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of HSPB8 mRNA; [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of MAP1LC3A mRNA; [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of MGRN1 mRNA; [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of PRKAB2 mRNA; [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of SEC63 mRNA; [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of SMPD3 mRNA; [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of TOPORS mRNA; [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of UBR2 mRNA; Fenofibrate binds to and results in increased activity of PPARA protein; Fenofibrate inhibits the reaction [Zoledronic Acid results in decreased expression of PPARA mRNA]; Fenofibrate promotes the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; Fenofibrate results in increased expression of and results in increased activity of PPARA protein; Lipopolysaccharides inhibits the reaction [Fenofibrate results in increased expression of PPARA mRNA]; NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of PPARA mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of PPARA mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACACA mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACACB mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACLY mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACOX1 mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACOX1 protein]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACSL1 mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACSL1 protein]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of CYP4A10 mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of CYP4A14 mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ELOVL6 mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of FASN mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of LPL mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of LPL protein]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ME1 mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of NR1H3 mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of SCD1 mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of SCD2 mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of SLC27A4 mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of SLC27A4 protein]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of UCP2 mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of UCP2 protein]; PPARA promotes the reaction [Fenofibrate results in decreased expression of FGA mRNA]; PPARA protein affects the reaction [Fenofibrate affects the expression of BRAP mRNA]; PPARA protein affects the reaction [Fenofibrate promotes the reaction [APOA1 protein results in increased secretion of Lipids]]; PPARA protein affects the reaction [Fenofibrate results in decreased expression of ANAPC11 mRNA]; PPARA protein affects the reaction [Fenofibrate results in decreased expression of CISH mRNA]; PPARA protein affects the reaction [Fenofibrate results in decreased expression of CYLD mRNA]; PPARA protein affects the reaction [Fenofibrate results in decreased expression of DNAJB4 mRNA]; PPARA protein affects the reaction [Fenofibrate results in decreased expression of HSPA13 mRNA]; PPARA protein affects the reaction [Fenofibrate results in decreased expression of ITCH mRNA]; PPARA protein affects the reaction [Fenofibrate results in decreased expression of LNX1 mRNA]; PPARA protein affects the reaction [Fenofibrate results in decreased expression of LRSAM1 mRNA]; PPARA protein affects the reaction [Fenofibrate results in decreased expression of PDRG1 mRNA]; PPARA protein affects the reaction [Fenofibrate results in decreased expression of PPP3CA mRNA]; PPARA protein affects the reaction [Fenofibrate results in decreased expression of PRKAB1 mRNA]; PPARA protein affects the reaction [Fenofibrate results in decreased expression of RBJ mRNA]; PPARA protein affects the reaction [Fenofibrate results in decreased expression of RNF144B mRNA]; PPARA protein affects the reaction [Fenofibrate results in decreased expression of UBE2R2 mRNA]; PPARA protein affects the reaction [Fenofibrate results in decreased expression of URM1 mRNA]; PPARA protein affects the reaction [Fenofibrate results in decreased expression of USP36 mRNA]; PPARA protein affects the reaction [Fenofibrate results in decreased expression of WSB1 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of ACADM mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of ARIH1 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of ATE1 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of ATG12 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of ATG7 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of CANX mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of CBLB mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of CNOT4 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of DNAJA2 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of DNAJB6 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of DNAJC3 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of DNAJC5 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of ENC1 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of FBXO3 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of FBXO30 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of FBXO32 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of FOXO1 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of GRPEL2 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of HSP90AA1 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of HSP90AB1 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of HSPA4L mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of HSPA8 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of HSPA9 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of HSPB1 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of HSPH1 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of NEDD4 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of PJA2 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of PPP1R15B mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of PSMB2 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of PSMC6 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of PSMD4 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of RABGEF1 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of RNF14 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of SENP2 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of SOCS6 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of SPOP mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of TOR1B mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of TOR3A mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of TRIM63 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of TRIP12 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of UBE2Q2 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of UBE3A mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of URI1 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of USP1 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of USP10 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of USP22 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of USP38 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of USP7 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of USP9X mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of USPL1 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of VCPIP1 mRNA] Fenofibrate results in increased expression of PPARA mRNA; Fenofibrate results in increased expression of PPARA protein PPARA protein results in increased susceptibility to Fenofibrate; PPARA results in increased susceptibility to Fenofibrate [Fenofibrate binds to and results in increased activity of PPARA protein] which results in increased expression of UCP2 mRNA; EDN1 protein promotes the reaction [Fenofibrate promotes the reaction [NFATC4 protein binds to PPARA protein]]; Fenofibrate binds to and results in increased activity of PPARA protein; Fenofibrate inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Dietary Carbohydrates] results in increased expression of PPARA protein]; Fenofibrate inhibits the reaction [Fructose results in decreased expression of and results in decreased activity of PPARA protein]; Fenofibrate inhibits the reaction [Pyrazinamide results in decreased expression of PPARA mRNA]; Fenofibrate inhibits the reaction [tert-Butylhydroperoxide results in decreased expression of PPARA mRNA]; Fenofibrate inhibits the reaction [tert-Butylhydroperoxide results in decreased expression of PPARA protein]; Fenofibrate promotes the reaction [NFATC4 protein binds to PPARA protein]; Fenofibrate promotes the reaction [PPARA protein results in increased expression of MLYCD mRNA]; PPARA mutant form inhibits the reaction [Fenofibrate inhibits the reaction [EDN1 protein promotes the reaction [NFATC4 protein binds to GATA4 protein]]]; PPARA mutant form inhibits the reaction [Fenofibrate inhibits the reaction [EDN1 protein results in increased expression of NPPB mRNA]] |
CTD RGD |
PMID:7983038 PMID:10216095 PMID:11341955 PMID:11798191 PMID:11934685 PMID:12759900 PMID:14641110 PMID:15299082 PMID:15968640 PMID:16569247 PMID:17201732 PMID:17655842 PMID:18300857 PMID:18338635 PMID:18356826 PMID:18812576 PMID:19118567 PMID:19124612 PMID:19201410 PMID:19445040 PMID:19569716 PMID:19593819 PMID:20520642 PMID:21300114 PMID:21318169 PMID:22198280 PMID:23063693 PMID:24735863 PMID:24752549 PMID:24986865 PMID:25035112 PMID:25689681 PMID:25949234 PMID:26989860 PMID:27071702 PMID:28743512 PMID:28871336 PMID:29134746 PMID:30203046 PMID:30611848 PMID:33408297 PMID:11934685 More...
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RGD:628329 |
NCBI chr22:46,150,526...46,243,756
Ensembl chr22:46,150,521...46,243,755
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G |
PPARD |
peroxisome proliferator activated receptor delta |
increases expression multiple interactions |
EXP ISO |
Fenofibrate results in increased expression of PPARD mRNA Fenofibrate inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Dietary Carbohydrates] results in increased expression of PPARD protein] |
CTD |
PMID:18338635 PMID:19201410 |
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NCBI chr 6:35,342,558...35,428,178
Ensembl chr 6:35,342,558...35,428,191
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G |
PPARG |
peroxisome proliferator activated receptor gamma |
increases expression affects activity multiple interactions |
EXP ISO |
Fenofibrate results in increased expression of PPARG mRNA Fenofibrate affects the activity of PPARG protein [Oleic Acid co-treated with Fenofibrate] results in increased expression of PPARG mRNA |
CTD |
PMID:19201410 PMID:24534255 PMID:25596134 PMID:28034800 |
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NCBI chr 3:12,287,368...12,434,344
Ensembl chr 3:12,287,368...12,434,356
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G |
PPARGC1A |
PPARG coactivator 1 alpha |
multiple interactions |
ISO EXP |
Fenofibrate inhibits the reaction [zoledronic acid results in decreased expression of PPARGC1A mRNA] Fenofibrate inhibits the reaction [[Fructose co-treated with Palmitic Acid] results in decreased expression of PPARGC1A protein] |
CTD |
PMID:28871336 PMID:32730863 |
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NCBI chr 4:23,792,021...24,472,905
Ensembl chr 4:23,755,041...23,904,089
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G |
PPCS |
phosphopantothenoylcysteine synthetase |
increases expression |
ISO |
Fenofibrate results in increased expression of PPCS mRNA |
CTD |
PMID:27665778 |
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NCBI chr 1:42,456,341...42,473,417
Ensembl chr 1:42,456,117...42,473,385
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G |
PPM1D |
protein phosphatase, Mg2+/Mn2+ dependent 1D |
decreases expression |
ISO |
Fenofibrate results in decreased expression of PPM1D mRNA |
CTD |
PMID:25596134 |
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NCBI chr17:60,600,193...60,666,280
Ensembl chr17:60,600,193...60,666,280
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G |
PPP1R15A |
protein phosphatase 1 regulatory subunit 15A |
increases expression decreases expression |
EXP ISO |
Fenofibrate results in increased expression of PPP1R15A mRNA Fenofibrate results in decreased expression of PPP1R15A mRNA |
CTD |
PMID:25596134 |
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NCBI chr19:48,872,421...48,876,058
Ensembl chr19:48,872,212...48,876,059
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G |
PPP1R15B |
protein phosphatase 1 regulatory subunit 15B |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of PPP1R15B mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of PPP1R15B mRNA] |
CTD |
PMID:21318169 |
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NCBI chr 1:204,395,826...204,411,817
Ensembl chr 1:204,396,492...204,411,887
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G |
PPP3CA |
protein phosphatase 3 catalytic subunit alpha |
multiple interactions decreases expression |
ISO |
PPARA protein affects the reaction [Fenofibrate results in decreased expression of PPP3CA mRNA] |
CTD |
PMID:21318169 |
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NCBI chr 4:101,023,418...101,347,526
Ensembl chr 4:101,023,409...101,348,278
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G |
PRKAA1 |
protein kinase AMP-activated catalytic subunit alpha 1 |
multiple interactions decreases response to substance |
EXP |
PRKAA1 protein affects the reaction [Fenofibrate results in decreased susceptibility to ALB protein modified form]; PRKAA1 protein affects the reaction [Fenofibrate results in increased abundance of Nitric Oxide]; PRKAA1 protein affects the reaction [Fenofibrate results in increased activity of NOS3 protein] PRKAA1 gene mutant form results in decreased susceptibility to Fenofibrate |
CTD |
PMID:20580385 PMID:25545733 |
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NCBI chr 5:40,759,389...40,798,374
Ensembl chr 5:40,759,389...40,798,374
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G |
PRKAB1 |
protein kinase AMP-activated non-catalytic subunit beta 1 |
decreases expression increases phosphorylation multiple interactions |
ISO EXP |
Fenofibrate results in decreased expression of PRKAB1 mRNA Fenofibrate results in increased phosphorylation of PRKAB1 protein PPARA protein affects the reaction [Fenofibrate results in decreased expression of PRKAB1 mRNA] |
CTD |
PMID:21318169 PMID:25545733 |
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NCBI chr12:119,667,952...119,681,619
Ensembl chr12:119,667,864...119,681,624
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G |
PRKAB2 |
protein kinase AMP-activated non-catalytic subunit beta 2 |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of PRKAB2 mRNA [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of PRKAB2 mRNA |
CTD |
PMID:21318169 |
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NCBI chr 1:147,155,106...147,172,470
Ensembl chr 1:147,155,106...147,172,550
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G |
PRKAG1 |
protein kinase AMP-activated non-catalytic subunit gamma 1 |
increases expression |
EXP |
Fenofibrate results in increased expression of PRKAG1 protein |
CTD |
PMID:25545733 |
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NCBI chr12:49,002,274...49,018,776
Ensembl chr12:49,002,274...49,018,807
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G |
PRODH |
proline dehydrogenase 1 |
decreases expression |
EXP |
Fenofibrate results in decreased expression of PRODH mRNA |
CTD |
PMID:25572481 |
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NCBI chr22:18,912,781...18,936,553
Ensembl chr22:18,912,777...18,936,553
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G |
PRRG4 |
proline rich and Gla domain 4 |
increases expression |
ISO |
Fenofibrate results in increased expression of PRRG4 mRNA |
CTD |
PMID:32741897 |
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NCBI chr11:32,829,789...32,858,120
Ensembl chr11:32,829,927...32,858,120
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G |
PSEN1 |
presenilin 1 |
multiple interactions |
EXP |
Fenofibrate affects the reaction [PSEN1 protein affects the cleavage of APP protein] |
CTD |
PMID:17962197 |
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NCBI chr14:73,136,417...73,223,691
Ensembl chr14:73,136,418...73,223,691
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G |
PSMB2 |
proteasome 20S subunit beta 2 |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of PSMB2 mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of PSMB2 mRNA] |
CTD |
PMID:21318169 |
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NCBI chr 1:35,599,541...35,641,526
Ensembl chr 1:35,599,541...35,641,526
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G |
PSMC6 |
proteasome 26S subunit, ATPase 6 |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of PSMC6 mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of PSMC6 mRNA] |
CTD |
PMID:21318169 |
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NCBI chr14:52,707,200...52,728,590
Ensembl chr14:52,707,178...52,728,590
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G |
PSMD4 |
proteasome 26S subunit ubiquitin receptor, non-ATPase 4 |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of PSMD4 mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of PSMD4 mRNA] |
CTD |
PMID:21318169 |
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NCBI chr 1:151,254,734...151,267,479
Ensembl chr 1:151,254,709...151,267,479
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G |
PTGS1 |
prostaglandin-endoperoxide synthase 1 |
multiple interactions |
ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of PTGS1 mRNA |
CTD |
PMID:18253720 |
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NCBI chr 9:122,370,533...122,395,703
Ensembl chr 9:122,370,530...122,395,703
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G |
PTGS2 |
prostaglandin-endoperoxide synthase 2 |
multiple interactions |
ISO |
Fenofibrate inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA] |
CTD |
PMID:21300114 |
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NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922
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G |
PTPRF |
protein tyrosine phosphatase receptor type F |
affects expression |
ISO |
Fenofibrate affects the expression of PTPRF mRNA |
CTD |
PMID:20801182 |
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NCBI chr 1:43,522,051...43,623,666
Ensembl chr 1:43,525,187...43,623,666
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G |
PTPRQ |
protein tyrosine phosphatase receptor type Q |
decreases expression |
EXP |
Fenofibrate results in decreased expression of PTPRQ mRNA |
CTD |
PMID:25572481 |
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NCBI chr12:80,444,235...80,680,273
Ensembl chr12:80,402,178...80,680,273
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G |
PYGL |
glycogen phosphorylase L |
increases expression |
ISO |
Fenofibrate results in increased expression of PYGL mRNA |
CTD |
PMID:25596134 |
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NCBI chr14:50,905,217...50,944,483
Ensembl chr14:50,857,891...50,944,483
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G |
QPCT |
glutaminyl-peptide cyclotransferase |
increases expression |
ISO |
Fenofibrate results in increased expression of QPCT mRNA |
CTD |
PMID:27665778 PMID:32741897 |
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NCBI chr 2:37,344,630...37,373,322
Ensembl chr 2:37,342,827...37,373,322
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G |
RAB30 |
RAB30, member RAS oncogene family |
increases expression |
ISO |
Fenofibrate results in increased expression of RAB30 mRNA |
CTD |
PMID:32741897 |
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NCBI chr11:82,973,133...83,071,897
Ensembl chr11:82,973,133...83,071,923
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G |
RAB31 |
RAB31, member RAS oncogene family |
decreases expression |
EXP |
Fenofibrate results in decreased expression of RAB31 mRNA |
CTD |
PMID:25596134 |
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NCBI chr18:9,708,301...9,862,551
Ensembl chr18:9,708,275...9,862,551
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G |
RABGEF1 |
RAB guanine nucleotide exchange factor 1 |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of RABGEF1 mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of RABGEF1 mRNA] |
CTD |
PMID:21318169 |
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NCBI chr 7:66,654,567...66,811,464
Ensembl chr 7:66,682,164...66,811,464
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G |
RAD50 |
RAD50 double strand break repair protein |
multiple interactions |
ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of RAD50 mRNA |
CTD |
PMID:18253720 |
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NCBI chr 5:132,556,977...132,646,349
Ensembl chr 5:132,556,019...132,646,349
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G |
RAD51B |
RAD51 paralog B |
increases expression |
ISO |
Fenofibrate results in increased expression of RAD51B mRNA |
CTD |
PMID:11798191 |
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NCBI chr14:67,819,779...68,683,096
Ensembl chr14:67,819,779...68,730,218
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G |
RAET1E |
retinoic acid early transcript 1E |
increases expression |
ISO |
Fenofibrate results in increased expression of RAET1E mRNA |
CTD |
PMID:11798191 |
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NCBI chr 6:149,883,179...149,898,113
Ensembl chr 6:149,883,179...149,898,113
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G |
RAMP2 |
receptor activity modifying protein 2 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of RAMP2 mRNA |
CTD |
PMID:11798191 |
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NCBI chr17:42,761,227...42,763,041
Ensembl chr17:42,758,447...42,763,041
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G |
RARA |
retinoic acid receptor alpha |
multiple interactions decreases expression |
ISO EXP |
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of RARA mRNA Fenofibrate results in decreased expression of RARA mRNA |
CTD |
PMID:18253720 PMID:25596134 |
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NCBI chr17:40,309,180...40,357,643
Ensembl chr17:40,309,180...40,357,643
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G |
RARB |
retinoic acid receptor beta |
multiple interactions |
ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of RARB mRNA |
CTD |
PMID:18253720 |
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NCBI chr 3:24,829,321...25,597,932
Ensembl chr 3:24,687,887...25,597,932
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G |
RBP2 |
retinol binding protein 2 |
increases expression |
ISO |
Fenofibrate results in increased expression of RBP2 mRNA |
CTD |
PMID:32741897 |
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NCBI chr 3:139,452,884...139,476,516
Ensembl chr 3:139,452,884...139,480,747
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G |
RBX1 |
ring-box 1 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of RBX1 mRNA |
CTD |
PMID:21318169 |
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NCBI chr22:40,951,378...40,973,309
Ensembl chr22:40,951,347...40,973,309
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G |
RDH16 |
retinol dehydrogenase 16 |
increases expression |
ISO |
Fenofibrate results in increased expression of RDH16 mRNA |
CTD |
PMID:11798191 |
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NCBI chr12:56,951,431...56,957,608
Ensembl chr12:56,951,431...56,959,374
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G |
RELA |
RELA proto-oncogene, NF-kB subunit |
multiple interactions |
EXP ISO |
Fenofibrate affects the localization of and results in decreased activity of RELA protein; Fenofibrate inhibits the reaction [ALB protein modified form results in increased expression of RELA protein]; Fenofibrate inhibits the reaction [Glucose results in increased expression of RELA protein]; Fenofibrate results in decreased localization of and results in decreased activity of RELA protein [Fenofibrate co-treated with Sodium Glutamate] results in increased expression of RELA protein; Fenofibrate inhibits the reaction [Dietary Fats results in increased expression of RELA protein]; Fenofibrate inhibits the reaction [Doxorubicin results in increased expression of RELA protein]; Fenofibrate promotes the reaction [Pioglitazone inhibits the reaction [Doxorubicin results in increased expression of RELA protein]]; Pioglitazone promotes the reaction [Fenofibrate inhibits the reaction [Doxorubicin results in increased expression of RELA protein]] |
CTD |
PMID:16600694 PMID:20520642 PMID:20580385 PMID:21999347 PMID:25545733 PMID:36988379 PMID:38216941 More...
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NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090
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G |
RETN |
resistin |
multiple interactions |
EXP |
Fenofibrate inhibits the reaction [Arsenic Trioxide results in increased expression of and results in increased secretion of RETN protein] |
CTD |
PMID:32929351 |
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NCBI chr19:7,669,049...7,670,455
Ensembl chr19:7,669,049...7,670,455
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G |
RETSAT |
retinol saturase |
increases expression |
ISO |
Fenofibrate results in increased expression of RETSAT mRNA |
CTD |
PMID:11798191 |
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NCBI chr 2:85,341,955...85,354,528
Ensembl chr 2:85,341,955...85,354,531
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G |
RGS16 |
regulator of G protein signaling 16 |
increases expression |
ISO |
Fenofibrate results in increased expression of RGS16 mRNA |
CTD |
PMID:32741897 |
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NCBI chr 1:182,598,623...182,604,389
Ensembl chr 1:182,598,623...182,604,389
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G |
RHOF |
ras homolog family member F, filopodia associated |
increases expression |
ISO |
Fenofibrate results in increased expression of RHOF mRNA |
CTD |
PMID:32741897 |
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NCBI chr12:121,777,754...121,793,688
Ensembl chr12:121,777,754...121,803,403
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G |
RLF |
RLF zinc finger |
increases expression |
ISO |
Fenofibrate results in increased expression of RLF mRNA |
CTD |
PMID:25596134 |
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NCBI chr 1:40,161,387...40,240,921
Ensembl chr 1:40,161,387...40,240,921
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G |
RND1 |
Rho family GTPase 1 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of RND1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr12:48,857,145...48,865,870
Ensembl chr12:48,857,145...48,865,870
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G |
RND3 |
Rho family GTPase 3 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of RND3 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 2:150,468,193...150,487,695
Ensembl chr 2:150,468,195...150,539,011
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G |
RNF125 |
ring finger protein 125 |
increases expression |
ISO |
Fenofibrate results in increased expression of RNF125 mRNA |
CTD |
PMID:21318169 |
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NCBI chr18:32,018,825...32,088,144
Ensembl chr18:32,018,825...32,088,144
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G |
RNF14 |
ring finger protein 14 |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of RNF14 mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of RNF14 mRNA] |
CTD |
PMID:21318169 |
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NCBI chr 5:141,949,337...141,990,292
Ensembl chr 5:141,958,328...141,990,292
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G |
RNF144B |
ring finger protein 144B |
decreases expression multiple interactions |
ISO |
Fenofibrate results in decreased expression of RNF144B mRNA PPARA protein affects the reaction [Fenofibrate results in decreased expression of RNF144B mRNA] |
CTD |
PMID:21318169 |
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NCBI chr 6:18,387,350...18,468,870
Ensembl chr 6:18,387,350...18,468,870
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G |
RNF19A |
ring finger protein 19A, RBR E3 ubiquitin protein ligase |
increases expression |
ISO |
Fenofibrate results in increased expression of RNF19A mRNA |
CTD |
PMID:21318169 |
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NCBI chr 8:100,257,067...100,336,204
Ensembl chr 8:100,257,060...100,336,218
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G |
RO60 |
Ro60, Y RNA binding protein |
decreases expression |
EXP |
Fenofibrate results in decreased expression of RO60 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 1:193,059,612...193,091,777
Ensembl chr 1:193,059,454...193,091,777
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G |
RSRC2 |
arginine and serine rich coiled-coil 2 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of RSRC2 mRNA |
CTD |
PMID:25596134 |
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NCBI chr12:122,503,454...122,526,936
Ensembl chr12:122,503,454...122,527,000
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G |
RXRA |
retinoid X receptor alpha |
decreases expression affects expression |
EXP ISO |
Fenofibrate results in decreased expression of RXRA mRNA Fenofibrate affects the expression of RXRA mRNA |
CTD |
PMID:25596134 |
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NCBI chr 9:134,326,455...134,440,585
Ensembl chr 9:134,317,098...134,440,585
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G |
S100A10 |
S100 calcium binding protein A10 |
increases expression |
ISO |
Fenofibrate results in increased expression of S100A10 mRNA |
CTD |
PMID:11798191 |
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NCBI chr 1:151,982,915...151,993,859
Ensembl chr 1:151,982,915...151,993,859
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G |
SAA1 |
serum amyloid A1 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of SAA1 mRNA |
CTD |
PMID:11798191 |
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NCBI chr11:18,266,264...18,269,967
Ensembl chr11:18,266,260...18,269,977
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G |
SAA2 |
serum amyloid A2 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of SAA2 mRNA |
CTD |
PMID:11798191 |
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NCBI chr11:18,238,236...18,248,668
Ensembl chr11:18,239,223...18,248,668
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G |
SAA3P |
serum amyloid A3, pseudogene |
decreases expression |
ISO |
Fenofibrate results in decreased expression of SAA3 mRNA |
CTD |
PMID:11798191 |
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NCBI chr11:18,112,472...18,116,132
Ensembl chr11:18,112,472...18,116,132 Ensembl chr11:18,112,472...18,116,132
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G |
SARS1 |
seryl-tRNA synthetase 1 |
increases expression |
ISO |
Fenofibrate results in increased expression of SARS1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 1:109,213,893...109,238,182
Ensembl chr 1:109,213,918...109,238,182
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G |
SAT1 |
spermidine/spermine N1-acetyltransferase 1 |
increases expression |
ISO |
Fenofibrate results in increased expression of SAT1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr X:23,783,173...23,786,210
Ensembl chr X:23,783,173...23,786,210
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G |
SCAMP1 |
secretory carrier membrane protein 1 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of SCAMP1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 5:78,360,617...78,480,739
Ensembl chr 5:78,360,611...78,480,739
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G |
SCARB1 |
scavenger receptor class B member 1 |
multiple interactions decreases activity increases expression |
EXP ISO |
[Aspirin co-treated with Fenofibrate] results in increased expression of SCARB1 protein Fenofibrate results in decreased activity of SCARB1 protein Fenofibrate inhibits the reaction [SCARB1 protein results in increased export of Cholesterol, HDL]; Fenofibrate inhibits the reaction [SCARB1 protein results in increased uptake of cholesteryl oleyl ether] Fenofibrate results in increased expression of SCARB1 protein |
CTD |
PMID:16816107 PMID:17533223 |
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NCBI chr12:124,776,856...124,863,864
Ensembl chr12:124,776,856...124,882,668
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G |
SCD |
stearoyl-CoA desaturase |
multiple interactions increases expression affects expression |
EXP ISO |
[Oleic Acid co-treated with Fenofibrate] results in increased expression of SCD1 mRNA NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of SCD2 mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of SCD2 mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of SCD2 mRNA] Fenofibrate results in increased expression of SCD mRNA; Fenofibrate results in increased expression of SCD2 mRNA Fenofibrate affects the expression of SCD mRNA |
CTD |
PMID:17118139 PMID:23063693 PMID:24534255 PMID:27665778 |
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NCBI chr10:100,347,233...100,364,826
Ensembl chr10:100,347,233...100,364,826
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G |
SCLY |
selenocysteine lyase |
affects expression |
ISO |
Fenofibrate affects the expression of SCLY mRNA |
CTD |
PMID:20801182 |
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NCBI chr 2:238,061,001...238,099,413
Ensembl chr 2:238,060,924...238,099,413
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G |
SDHB |
succinate dehydrogenase complex iron sulfur subunit B |
increases expression |
EXP |
Fenofibrate results in increased expression of SDHB protein |
CTD |
PMID:24752549 |
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NCBI chr 1:17,018,722...17,054,032
Ensembl chr 1:17,018,664...17,054,151
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G |
SEC63 |
SEC63 homolog, protein translocation regulator |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of SEC63 mRNA [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of SEC63 mRNA |
CTD |
PMID:21318169 |
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NCBI chr 6:107,867,756...107,958,208
Ensembl chr 6:107,867,756...107,958,208
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G |
SELE |
selectin E |
multiple interactions |
EXP |
dorsomorphin inhibits the reaction [Fenofibrate inhibits the reaction [ALB protein modified form results in increased expression of SELE mRNA]]; Fenofibrate inhibits the reaction [ALB protein modified form results in increased expression of SELE mRNA] |
CTD |
PMID:20580385 |
|
NCBI chr 1:169,722,640...169,734,079
Ensembl chr 1:169,722,640...169,764,705
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G |
SEMA6B |
semaphorin 6B |
multiple interactions decreases expression |
EXP |
alitretinoin promotes the reaction [Fenofibrate results in decreased expression of SEMA6B mRNA]; alitretinoin promotes the reaction [Fenofibrate results in decreased expression of SEMA6B protein] Fenofibrate results in decreased expression of SEMA6B mRNA; Fenofibrate results in decreased expression of SEMA6B protein |
CTD |
PMID:16525649 |
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NCBI chr19:4,542,593...4,559,684
Ensembl chr19:4,542,588...4,581,776
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G |
SENP2 |
SUMO specific peptidase 2 |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of SENP2 mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of SENP2 mRNA] |
CTD |
PMID:21318169 |
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NCBI chr 3:185,586,295...185,633,551
Ensembl chr 3:185,582,496...185,633,551
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G |
SERPINA3 |
serpin family A member 3 |
affects expression |
ISO |
Fenofibrate affects the expression of SERPINA3N mRNA |
CTD |
PMID:20801182 |
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NCBI chr14:94,612,391...94,624,053
Ensembl chr14:94,612,384...94,624,055
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G |
SERPINE1 |
serpin family E member 1 |
multiple interactions affects expression |
EXP ISO |
Fenofibrate inhibits the reaction [NR4A1 protein results in increased expression of SERPINE1 mRNA]; Fenofibrate inhibits the reaction [SMAD3 protein results in increased expression of SERPINE1 mRNA]; Fenofibrate inhibits the reaction [SMAD4 protein results in increased expression of SERPINE1 mRNA]; Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of SERPINE1 mRNA]; Fenofibrate inhibits the reaction [TNF protein results in increased expression of SERPINE1 mRNA]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [NR4A1 protein results in increased expression of SERPINE1 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [SMAD3 protein results in increased expression of SERPINE1 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [SMAD4 protein results in increased expression of SERPINE1 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of SERPINE1 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [TNF protein results in increased expression of SERPINE1 mRNA]] [Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of SERPINE1 mRNA Fenofibrate affects the expression of SERPINE1 mRNA Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of SERPINE1 mRNA]; Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of SERPINE1 mRNA]; NR0B2 protein inhibits the reaction [Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of SERPINE1 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of SERPINE1 mRNA]] |
CTD |
PMID:18253720 PMID:19593819 PMID:20801182 |
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NCBI chr 7:101,127,104...101,139,247
Ensembl chr 7:101,127,104...101,139,247
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G |
SERTAD1 |
SERTA domain containing 1 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of SERTAD1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr19:40,421,589...40,425,992
Ensembl chr19:40,421,589...40,425,992
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G |
SESN1 |
sestrin 1 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of SESN1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 6:108,984,309...109,094,846
Ensembl chr 6:108,984,309...109,094,846
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G |
SGK2 |
serum/glucocorticoid regulated kinase 2 |
increases expression |
EXP |
Fenofibrate results in increased expression of SGK2 mRNA |
CTD |
PMID:25572481 |
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NCBI chr20:43,559,027...43,585,627
Ensembl chr20:43,558,968...43,588,237
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G |
SH3BGRL2 |
SH3 domain binding glutamate rich protein like 2 |
increases expression |
EXP |
Fenofibrate results in increased expression of SH3BGRL2 mRNA |
CTD |
PMID:25572481 |
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NCBI chr 6:79,537,633...79,703,655
Ensembl chr 6:79,537,185...79,703,655
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G |
SH3TC1 |
SH3 domain and tetratricopeptide repeats 1 |
increases expression |
EXP |
Fenofibrate results in increased expression of SH3TC1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 4:8,182,072...8,241,103
Ensembl chr 4:8,182,072...8,241,803
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G |
SIAH2 |
siah E3 ubiquitin protein ligase 2 |
affects expression |
ISO |
Fenofibrate affects the expression of SIAH2 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 3:150,741,125...150,763,169
Ensembl chr 3:150,741,125...150,763,477
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G |
SIK1 |
salt inducible kinase 1 |
increases expression decreases expression |
EXP ISO |
Fenofibrate results in increased expression of SIK1 mRNA Fenofibrate results in decreased expression of SIK1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr21:43,414,483...43,427,131
Ensembl chr21:43,414,483...43,427,131
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G |
SIRT1 |
sirtuin 1 |
multiple interactions increases expression |
EXP ISO |
dorsomorphin inhibits the reaction [Fenofibrate results in increased expression of SIRT1 protein]; Fenofibrate inhibits the reaction [[Fructose co-treated with Palmitic Acid] results in decreased expression of SIRT1 protein]; zinc protoporphyrin inhibits the reaction [Fenofibrate results in increased expression of SIRT1 protein] |
CTD |
PMID:32730863 PMID:34520103 |
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NCBI chr10:67,884,656...67,918,390
Ensembl chr10:67,884,656...67,918,390
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G |
SIVA1 |
SIVA1 apoptosis inducing factor |
decreases expression |
ISO |
Fenofibrate results in decreased expression of SIVA1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr14:104,753,147...104,759,654
Ensembl chr14:104,753,147...104,768,494
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G |
SLC10A1 |
solute carrier family 10 member 1 |
decreases expression |
EXP ISO |
Fenofibrate results in decreased expression of SLC10A1 mRNA |
CTD |
PMID:25572481 PMID:27765674 |
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NCBI chr14:69,775,416...69,797,241
Ensembl chr14:69,775,416...69,797,241
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G |
SLC16A13 |
solute carrier family 16 member 13 |
increases expression |
EXP |
Fenofibrate results in increased expression of SLC16A13 mRNA |
CTD |
PMID:25572481 |
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NCBI chr17:7,036,015...7,040,117
Ensembl chr17:7,036,015...7,040,117
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G |
SLC16A6 |
solute carrier family 16 member 6 |
increases expression |
ISO |
Fenofibrate results in increased expression of SLC16A6 mRNA |
CTD |
PMID:25596134 |
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NCBI chr17:68,267,026...68,291,479
Ensembl chr17:68,267,026...68,291,267
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G |
SLC1A7 |
solute carrier family 1 member 7 |
increases expression |
EXP |
Fenofibrate results in increased expression of SLC1A7 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 1:53,087,183...53,142,638
Ensembl chr 1:53,087,179...53,142,638
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G |
SLC22A5 |
solute carrier family 22 member 5 |
increases expression |
ISO |
Fenofibrate results in increased expression of SLC22A5 mRNA |
CTD |
PMID:27665778 PMID:32741897 |
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NCBI chr 5:132,369,710...132,395,612
Ensembl chr 5:132,369,710...132,395,613
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G |
SLC25A20 |
solute carrier family 25 member 20 |
increases expression |
ISO EXP |
Fenofibrate results in increased expression of SLC25A20 mRNA |
CTD |
PMID:16707586 PMID:25572481 PMID:25596134 |
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NCBI chr 3:48,856,926...48,898,882
Ensembl chr 3:48,856,926...48,898,904
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G |
SLC25A30 |
solute carrier family 25 member 30 |
increases expression |
ISO |
Fenofibrate results in increased expression of SLC25A30 mRNA |
CTD |
PMID:32741897 |
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NCBI chr13:45,393,316...45,434,016
Ensembl chr13:45,393,316...45,418,455
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G |
SLC25A34 |
solute carrier family 25 member 34 |
increases expression |
EXP |
Fenofibrate results in increased expression of SLC25A34 mRNA |
CTD |
PMID:25572481 |
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NCBI chr 1:15,736,258...15,741,392
Ensembl chr 1:15,736,258...15,741,392
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G |
SLC25A4 |
solute carrier family 25 member 4 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of SLC25A4 protein |
CTD |
PMID:20118634 |
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NCBI chr 4:185,143,266...185,150,382
Ensembl chr 4:185,143,266...185,150,382
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G |
SLC27A1 |
solute carrier family 27 member 1 |
increases expression |
ISO |
Fenofibrate results in increased expression of SLC27A1 mRNA |
CTD |
PMID:11798191 |
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NCBI chr19:17,468,767...17,506,168
Ensembl chr19:17,468,769...17,506,168
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G |
SLC27A2 |
solute carrier family 27 member 2 |
increases expression |
ISO EXP |
Fenofibrate results in increased expression of SLC27A2 mRNA |
CTD |
PMID:17118139 PMID:25572481 PMID:27665778 PMID:32741897 PMID:32741898 |
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NCBI chr15:50,182,196...50,236,385
Ensembl chr15:50,182,196...50,236,385
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G |
SLC27A4 |
solute carrier family 27 member 4 |
increases expression multiple interactions |
EXP ISO |
Fenofibrate results in increased expression of SLC27A4 mRNA; Fenofibrate results in increased expression of SLC27A4 protein PPARA protein promotes the reaction [Fenofibrate results in increased expression of SLC27A4 protein] PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of SLC27A4 mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of SLC27A4 protein] |
CTD |
PMID:24752549 |
|
NCBI chr 9:128,340,527...128,361,470
Ensembl chr 9:128,340,527...128,361,470
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G |
SLC34A2 |
solute carrier family 34 member 2 |
increases expression |
ISO |
Fenofibrate results in increased expression of SLC34A2 mRNA |
CTD |
PMID:32741897 |
|
NCBI chr 4:25,655,851...25,678,748
Ensembl chr 4:25,648,011...25,678,748
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G |
SLC3A2 |
solute carrier family 3 member 2 |
increases expression |
EXP ISO |
Fenofibrate results in increased expression of SLC3A2 mRNA |
CTD |
PMID:25596134 |
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NCBI chr11:62,856,109...62,888,860
Ensembl chr11:62,856,004...62,888,880
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G |
SLC6A9 |
solute carrier family 6 member 9 |
decreases expression increases expression |
ISO EXP |
Fenofibrate results in decreased expression of SLC6A9 mRNA Fenofibrate results in increased expression of SLC6A9 mRNA |
CTD |
PMID:25596134 |
|
NCBI chr 1:43,996,483...44,031,462
Ensembl chr 1:43,991,500...44,031,467
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G |
SLC7A1 |
solute carrier family 7 member 1 |
increases expression |
ISO EXP |
Fenofibrate results in increased expression of SLC7A1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr13:29,509,414...29,595,688
Ensembl chr13:29,509,414...29,595,688
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G |
SLC7A5 |
solute carrier family 7 member 5 |
increases expression |
EXP |
Fenofibrate results in increased expression of SLC7A5 mRNA |
CTD |
PMID:25596134 |
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NCBI chr16:87,830,023...87,869,507
Ensembl chr16:87,830,016...87,869,507
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G |
SLCO2B1 |
solute carrier organic anion transporter family member 2B1 |
decreases expression |
EXP ISO |
Fenofibrate results in decreased expression of SLCO2B1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr11:75,151,107...75,206,549
Ensembl chr11:75,100,563...75,206,549
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G |
SMAD3 |
SMAD family member 3 |
multiple interactions |
EXP |
Fenofibrate inhibits the reaction [SMAD3 protein results in increased expression of SERPINE1 mRNA]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [SMAD3 protein results in increased expression of SERPINE1 mRNA]] |
CTD |
PMID:19593819 |
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NCBI chr15:67,065,602...67,195,169
Ensembl chr15:67,063,763...67,195,173
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G |
SMAD4 |
SMAD family member 4 |
multiple interactions |
EXP |
Fenofibrate inhibits the reaction [SMAD4 protein results in increased expression of SERPINE1 mRNA]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [SMAD4 protein results in increased expression of SERPINE1 mRNA]] |
CTD |
PMID:19593819 |
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NCBI chr18:51,030,213...51,085,042
Ensembl chr18:51,028,528...51,085,045
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G |
SMPD2 |
sphingomyelin phosphodiesterase 2 |
multiple interactions |
ISO |
Fenofibrate promotes the reaction [Dextran Sulfate results in decreased expression of SMPD2 mRNA] |
CTD |
PMID:25035112 |
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NCBI chr 6:109,440,724...109,443,919
Ensembl chr 6:109,440,724...109,443,919
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G |
SMPD3 |
sphingomyelin phosphodiesterase 3 |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of SMPD3 mRNA [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of SMPD3 mRNA |
CTD |
PMID:21318169 |
|
NCBI chr16:68,358,327...68,448,508
Ensembl chr16:68,358,327...68,448,508
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G |
SMPD4 |
sphingomyelin phosphodiesterase 4 |
multiple interactions |
ISO |
Fenofibrate promotes the reaction [Dextran Sulfate results in decreased expression of SMPD4 mRNA] |
CTD |
PMID:25035112 |
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NCBI chr 2:130,151,392...130,181,757
Ensembl chr 2:130,151,392...130,182,750
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G |
SOCS3 |
suppressor of cytokine signaling 3 |
multiple interactions |
ISO |
[Fenofibrate co-treated with resveratrol] inhibits the reaction [Fructose results in increased expression of SOCS3 mRNA]; Fenofibrate inhibits the reaction [Fructose results in increased expression of SOCS3 mRNA] |
CTD |
PMID:26973390 |
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NCBI chr17:78,356,778...78,360,925
Ensembl chr17:78,356,778...78,360,077
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G |
SOCS6 |
suppressor of cytokine signaling 6 |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of SOCS6 mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of SOCS6 mRNA] |
CTD |
PMID:21318169 |
|
NCBI chr18:70,289,045...70,330,199
Ensembl chr18:70,289,045...70,330,199
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G |
SOCS7 |
suppressor of cytokine signaling 7 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of SOCS7 mRNA |
CTD |
PMID:21318169 |
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NCBI chr17:38,351,844...38,405,593
Ensembl chr17:38,351,844...38,405,593
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G |
SOD2 |
superoxide dismutase 2 |
increases expression |
ISO |
Fenofibrate results in increased expression of SOD2 mRNA |
CTD |
PMID:17264098 |
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NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529
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G |
SON |
SON DNA and RNA binding protein |
decreases expression |
ISO |
Fenofibrate results in decreased expression of SON mRNA |
CTD |
PMID:25596134 |
|
NCBI chr21:33,543,038...33,577,481
Ensembl chr21:33,543,038...33,577,481
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G |
SORL1 |
sortilin related receptor 1 |
increases expression decreases expression |
ISO EXP |
Fenofibrate results in increased expression of SORL1 mRNA Fenofibrate results in decreased expression of SORL1 mRNA |
CTD |
PMID:25596134 |
|
NCBI chr11:121,452,314...121,633,763
Ensembl chr11:121,452,314...121,633,763
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G |
SORT1 |
sortilin 1 |
increases expression |
ISO |
Fenofibrate results in increased expression of SORT1 mRNA |
CTD |
PMID:24986865 |
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NCBI chr 1:109,309,575...109,397,918
Ensembl chr 1:109,309,568...109,397,918
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G |
SPMIP11 |
sperm microtubule inner protein 11 |
increases expression |
ISO |
Fenofibrate results in increased expression of SPMIP11 mRNA |
CTD |
PMID:32741897 |
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NCBI chr12:48,727,435...48,771,459
Ensembl chr12:48,727,435...48,765,790
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G |
SPNS2 |
SPNS lysolipid transporter 2, sphingosine-1-phosphate |
increases expression |
EXP |
Fenofibrate results in increased expression of SPNS2 mRNA |
CTD |
PMID:25572481 |
|
NCBI chr17:4,498,881...4,539,035
Ensembl chr17:4,498,881...4,539,035
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G |
SPOP |
speckle type BTB/POZ protein |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of SPOP mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of SPOP mRNA] |
CTD |
PMID:21318169 |
|
NCBI chr17:49,598,884...49,678,163
Ensembl chr17:49,598,884...49,678,163
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G |
SPSB1 |
splA/ryanodine receptor domain and SOCS box containing 1 |
increases expression |
ISO |
Fenofibrate results in increased expression of SPSB1 mRNA |
CTD |
PMID:25596134 |
|
NCBI chr 1:9,292,894...9,369,532
Ensembl chr 1:9,292,894...9,369,532
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G |
SQLE |
squalene epoxidase |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of SQLE mRNA NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of SQLE mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of SQLE mRNA] |
CTD |
PMID:23063693 |
|
NCBI chr 8:124,998,505...125,022,283
Ensembl chr 8:124,998,497...125,022,283
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G |
SQSTM1 |
sequestosome 1 |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of SQSTM1 mRNA Fenofibrate inhibits the reaction [tyloxapol results in increased expression of SQSTM1 protein] |
CTD |
PMID:25596134 PMID:36905866 |
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NCBI chr 5:179,806,393...179,838,078
Ensembl chr 5:179,806,398...179,838,078
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G |
SRD5A3 |
steroid 5 alpha-reductase 3 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of SRD5A3 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 4:55,346,242...55,373,100
Ensembl chr 4:55,346,213...55,373,100
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G |
SREBF1 |
sterol regulatory element binding transcription factor 1 |
multiple interactions increases expression |
ISO EXP |
Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of SREBF1 mRNA]; Fenofibrate inhibits the reaction [tyloxapol results in increased expression of SREBF1 protein]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of SREBF1 mRNA]]; NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of SREBF1 mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of SREBF1 mRNA] Fenofibrate inhibits the reaction [Fatty Acids, Nonesterified results in increased expression of SREBF1 mRNA]; Fenofibrate inhibits the reaction [Fatty Acids, Nonesterified results in increased expression of SREBF1 protein] [Fenofibrate co-treated with resveratrol] inhibits the reaction [Fructose results in increased expression of SREBF1 mRNA] |
CTD |
PMID:19593819 PMID:23063693 PMID:24735863 PMID:26973390 PMID:36905866 |
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NCBI chr17:17,811,334...17,836,986
Ensembl chr17:17,810,399...17,837,002
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SRXN1 |
sulfiredoxin 1 |
increases expression |
EXP |
Fenofibrate results in increased expression of SRXN1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr20:646,615...653,200
Ensembl chr20:646,615...653,200
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ST3GAL4 |
ST3 beta-galactoside alpha-2,3-sialyltransferase 4 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of ST3GAL4 mRNA |
CTD |
PMID:11798191 |
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NCBI chr11:126,355,686...126,414,638
Ensembl chr11:126,355,640...126,440,344
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STAT5B |
signal transducer and activator of transcription 5B |
decreases activity |
ISO |
Fenofibrate results in decreased activity of STAT5B protein |
CTD |
PMID:30114225 |
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NCBI chr17:42,199,177...42,288,370
Ensembl chr17:42,199,176...42,288,633
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STK11 |
serine/threonine kinase 11 |
multiple interactions |
EXP |
Fenofibrate results in increased expression of and results in increased phosphorylation of STK11 protein |
CTD |
PMID:25545733 |
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NCBI chr19:1,205,778...1,228,431
Ensembl chr19:1,177,558...1,228,431
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STRBP |
spermatid perinuclear RNA binding protein |
increases expression |
EXP |
Fenofibrate results in increased expression of STRBP mRNA |
CTD |
PMID:25596134 |
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NCBI chr 9:123,109,494...123,268,586
Ensembl chr 9:123,109,500...123,268,586
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SUCLG1 |
succinate-CoA ligase GDP/ADP-forming subunit alpha |
affects expression increases expression |
ISO EXP |
Fenofibrate affects the expression of SUCLG1 mRNA Fenofibrate results in increased expression of SUCLG1 protein Fenofibrate results in increased expression of SUCLG1 mRNA |
CTD |
PMID:16707586 PMID:20801182 PMID:24752549 |
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NCBI chr 2:84,423,528...84,459,280
Ensembl chr 2:84,423,528...84,460,045
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SULF2 |
sulfatase 2 |
decreases expression |
EXP ISO |
Fenofibrate results in decreased expression of SULF2 mRNA |
CTD |
PMID:25596134 |
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NCBI chr20:47,657,406...47,786,627
Ensembl chr20:47,656,197...47,786,616
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SULT1C2 |
sulfotransferase family 1C member 2 |
multiple interactions |
ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of SULT1C2 mRNA |
CTD |
PMID:18253720 |
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NCBI chr 2:108,288,895...108,309,915
Ensembl chr 2:108,288,639...108,309,915
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SULT1E1 |
sulfotransferase family 1E member 1 |
multiple interactions |
ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of SULT1E1 mRNA |
CTD |
PMID:18253720 |
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NCBI chr 4:69,821,122...69,860,145
Ensembl chr 4:69,841,212...69,860,145
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SULT4A1 |
sulfotransferase family 4A member 1 |
multiple interactions |
ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of SULT4A1 mRNA |
CTD |
PMID:18253720 |
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NCBI chr22:43,824,509...43,862,513
Ensembl chr22:43,824,509...43,862,513
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TALDO1 |
transaldolase 1 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of TALDO1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr11:747,464...765,012
Ensembl chr11:747,415...765,012
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TARS1 |
threonyl-tRNA synthetase 1 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of TARS1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 5:33,440,696...33,468,091
Ensembl chr 5:33,440,696...33,468,091
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TCP1 |
t-complex 1 |
multiple interactions |
ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of TCP1 mRNA |
CTD |
PMID:18253720 |
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NCBI chr 6:159,778,498...159,789,602
Ensembl chr 6:159,778,498...159,789,703
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TDO2 |
tryptophan 2,3-dioxygenase |
increases expression |
EXP |
Fenofibrate results in increased expression of TDO2 mRNA |
CTD |
PMID:25572481 |
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NCBI chr 4:155,903,696...155,920,406
Ensembl chr 4:155,854,738...155,920,406
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TFE3 |
transcription factor binding to IGHM enhancer 3 |
affects expression increases expression |
ISO EXP |
Fenofibrate affects the expression of TFE3 mRNA Fenofibrate results in increased expression of TFE3 mRNA |
CTD |
PMID:25596134 |
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NCBI chr X:49,028,726...49,043,357
Ensembl chr X:49,028,726...49,043,410
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TGFB1 |
transforming growth factor beta 1 |
multiple interactions |
EXP ISO |
Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 mRNA]; Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]; Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of SERPINE1 mRNA]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of SERPINE1 mRNA]] [Fenofibrate co-treated with resveratrol] inhibits the reaction [Fructose results in increased expression of TGFB1 mRNA]; Fenofibrate inhibits the reaction [Fructose results in increased expression of TGFB1 mRNA] Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of TGFB1 mRNA]; Fenofibrate inhibits the reaction [TGFB1 protein results in decreased expression of TRIB3 mRNA]; Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]; Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of IL6 mRNA]; Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of SERPINE1 mRNA]; Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of TIMP1 mRNA]; NR0B2 protein inhibits the reaction [Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]]; NR0B2 protein inhibits the reaction [Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of IL6 mRNA]]; NR0B2 protein inhibits the reaction [Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of SERPINE1 mRNA]]; NR0B2 protein inhibits the reaction [Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of TIMP1 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of TGFB1 mRNA]] |
CTD |
PMID:19593819 PMID:26973390 PMID:32613381 |
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NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922
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G |
THRSP |
thyroid hormone responsive |
multiple interactions decreases expression |
EXP |
Fenofibrate promotes the reaction [Oleic Acid results in decreased expression of THRSP mRNA] Fenofibrate results in decreased expression of THRSP mRNA |
CTD |
PMID:24534255 PMID:25572481 |
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NCBI chr11:78,063,861...78,068,351
Ensembl chr11:78,063,861...78,068,351
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G |
TIMP1 |
TIMP metallopeptidase inhibitor 1 |
multiple interactions |
ISO |
Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of TIMP1 mRNA]; Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of TIMP1 mRNA]; Fenofibrate inhibits the reaction [zoledronic acid results in increased expression of TIMP1 mRNA]; NR0B2 protein inhibits the reaction [Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of TIMP1 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of TIMP1 mRNA]] |
CTD |
PMID:19593819 PMID:28871336 |
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NCBI chr X:47,582,436...47,586,789
Ensembl chr X:47,582,408...47,586,789
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TIMP2 |
TIMP metallopeptidase inhibitor 2 |
multiple interactions |
ISO |
Fenofibrate inhibits the reaction [zoledronic acid results in increased expression of TIMP2 mRNA] |
CTD |
PMID:28871336 |
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NCBI chr17:78,852,977...78,925,387
Ensembl chr17:78,852,977...78,925,387
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G |
TIPARP |
TCDD inducible poly(ADP-ribose) polymerase |
increases expression |
ISO |
Fenofibrate results in increased expression of TIPARP mRNA |
CTD |
PMID:25596134 |
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NCBI chr 3:156,674,590...156,706,770
Ensembl chr 3:156,673,235...156,706,770
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TLR4 |
toll like receptor 4 |
multiple interactions |
ISO |
Fenofibrate inhibits the reaction [Cyclophosphamide results in increased expression of TLR4 protein] |
CTD |
PMID:38278497 |
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NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735
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G |
TMEM120A |
transmembrane protein 120A |
decreases expression increases expression |
EXP ISO |
Fenofibrate results in decreased expression of TMEM120A mRNA Fenofibrate results in increased expression of TMEM120A mRNA |
CTD |
PMID:25572481 PMID:32741897 |
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NCBI chr 7:75,986,831...75,994,595
Ensembl chr 7:75,986,831...75,994,656
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TNF |
tumor necrosis factor |
multiple interactions decreases expression decreases response to substance |
EXP ISO |
Fenofibrate affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA]; Fenofibrate inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of CD36 mRNA]; Fenofibrate inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein]; Fenofibrate inhibits the reaction [TNF protein results in increased expression of CCL5 mRNA]; Fenofibrate inhibits the reaction [TNF protein results in increased expression of CCL5 protein]; Fenofibrate inhibits the reaction [TNF protein results in increased expression of SERPINE1 mRNA]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [TNF protein results in increased expression of SERPINE1 mRNA]] [Fenofibrate co-treated with Resveratrol] inhibits the reaction [Fructose results in increased expression of and results in increased secretion of TNF protein]; [Fenofibrate co-treated with Sodium Glutamate] results in increased expression of TNF protein; Fenofibrate inhibits the reaction [Doxorubicin results in increased expression of TNF protein]; Fenofibrate inhibits the reaction [Fructose results in increased expression of and results in increased secretion of TNF protein]; Fenofibrate promotes the reaction [Pioglitazone inhibits the reaction [Doxorubicin results in increased expression of TNF protein]]; Pioglitazone promotes the reaction [Fenofibrate inhibits the reaction [Doxorubicin results in increased expression of TNF protein]] Fenofibrate results in decreased expression of TNF mRNA; Fenofibrate results in decreased expression of TNF protein [Fenofibrate co-treated with Alitretinoin] inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]; Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of TNF mRNA]; Fenofibrate inhibits the reaction [Cyclophosphamide results in increased expression of TNF protein]; Fenofibrate inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; Fenofibrate inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]; Fenofibrate inhibits the reaction [triptolide results in increased expression of TNF mRNA]; Fenofibrate promotes the reaction [Dextran Sulfate results in increased expression of TNF protein]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of TNF mRNA]] Fenofibrate results in decreased susceptibility to TNF protein; TNF protein results in decreased susceptibility to Fenofibrate |
CTD |
PMID:12586603 PMID:15968640 PMID:18356826 PMID:19593819 PMID:20520642 PMID:21300114 PMID:21999347 PMID:25035112 PMID:26973390 PMID:31241159 PMID:32613381 PMID:36988379 PMID:38278497 More...
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NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
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G |
TNFRSF10B |
TNF receptor superfamily member 10b |
increases expression |
EXP |
Fenofibrate results in increased expression of TNFRSF10B mRNA |
CTD |
PMID:25596134 |
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NCBI chr 8:23,020,133...23,069,031
Ensembl chr 8:23,020,133...23,069,031
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G |
TNFRSF11B |
TNF receptor superfamily member 11b |
decreases expression |
EXP |
Fenofibrate results in decreased expression of TNFRSF11B mRNA |
CTD |
PMID:25572481 |
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NCBI chr 8:118,923,557...118,951,885
Ensembl chr 8:118,923,557...118,951,885
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G |
TNFRSF21 |
TNF receptor superfamily member 21 |
increases expression |
EXP |
Fenofibrate results in increased expression of TNFRSF21 mRNA |
CTD |
PMID:25572481 PMID:25596134 |
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NCBI chr 6:47,231,532...47,309,905
Ensembl chr 6:47,231,532...47,309,905
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G |
TNNI3 |
troponin I3, cardiac type |
multiple interactions |
ISO |
Fenofibrate inhibits the reaction [Cyclophosphamide results in increased expression of TNNI3 protein] |
CTD |
PMID:38278497 |
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NCBI chr19:55,151,767...55,157,732
Ensembl chr19:55,151,767...55,157,773
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G |
TOP1 |
DNA topoisomerase I |
multiple interactions increases expression |
ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of TOP1 mRNA Fenofibrate results in increased expression of TOP1 mRNA |
CTD |
PMID:18253720 PMID:25596134 |
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NCBI chr20:41,028,822...41,124,487
Ensembl chr20:41,028,822...41,124,487
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TOP2A |
DNA topoisomerase II alpha |
increases expression |
ISO |
Fenofibrate results in increased expression of TOP2A mRNA |
CTD |
PMID:32741897 |
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NCBI chr17:40,388,525...40,417,896
Ensembl chr17:40,388,525...40,417,896
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G |
TOPORS |
TOP1 binding arginine/serine rich protein, E3 ubiquitin ligase |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of TOPORS mRNA [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of TOPORS mRNA |
CTD |
PMID:21318169 |
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NCBI chr 9:32,540,544...32,552,586
Ensembl chr 9:32,540,544...32,552,586
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G |
TOR1B |
torsin family 1 member B |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of TOR1B mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of TOR1B mRNA] |
CTD |
PMID:21318169 |
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NCBI chr 9:129,803,184...129,811,281
Ensembl chr 9:129,803,157...129,811,281
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G |
TOR3A |
torsin family 3 member A |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of TOR3A mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of TOR3A mRNA] |
CTD |
PMID:21318169 |
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NCBI chr 1:179,082,070...179,095,996
Ensembl chr 1:179,082,070...179,098,023
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G |
TP53 |
tumor protein p53 |
increases expression affects activity |
ISO EXP |
Fenofibrate results in increased expression of TP53 mRNA Fenofibrate affects the activity of TP53 protein |
CTD |
PMID:17264098 PMID:25596134 |
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NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,546
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TP53I3 |
tumor protein p53 inducible protein 3 |
decreases expression |
EXP |
Fenofibrate results in decreased expression of TP53I3 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 2:24,077,433...24,084,834
Ensembl chr 2:24,077,433...24,085,861
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TP53INP1 |
tumor protein p53 inducible nuclear protein 1 |
increases expression affects expression decreases expression |
ISO EXP |
Fenofibrate results in increased expression of TRP53INP1 mRNA Fenofibrate affects the expression of TP53INP1 mRNA Fenofibrate results in decreased expression of TP53INP1 mRNA |
CTD |
PMID:17264098 PMID:25596134 |
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NCBI chr 8:94,925,972...94,949,378
Ensembl chr 8:94,925,972...94,949,378
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TRAFD1 |
TRAF-type zinc finger domain containing 1 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of TRAFD1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr12:112,125,560...112,153,604
Ensembl chr12:112,125,538...112,153,604
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TRIAP1 |
TP53 regulated inhibitor of apoptosis 1 |
decreases expression |
EXP |
Fenofibrate results in decreased expression of TRIAP1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr12:120,443,964...120,446,384
Ensembl chr12:120,443,964...120,446,384
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G |
TRIB3 |
tribbles pseudokinase 3 |
multiple interactions decreases expression |
ISO EXP |
[Fenofibrate results in increased activity of PPARA protein] which results in increased expression of TRIB3 mRNA; Fenofibrate inhibits the reaction [TGFB1 protein results in decreased expression of TRIB3 mRNA] Fenofibrate results in decreased expression of TRIB3 mRNA Fenofibrate inhibits the reaction [Arsenic Trioxide results in increased expression of TRIB3 mRNA]; Fenofibrate inhibits the reaction [Arsenic Trioxide results in increased expression of TRIB3 protein] |
CTD |
PMID:19593819 PMID:32929351 |
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NCBI chr20:380,760...397,559
Ensembl chr20:362,835...397,559
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TRIM24 |
tripartite motif containing 24 |
increases expression |
EXP |
Fenofibrate results in increased expression of TRIM24 mRNA |
CTD |
PMID:25572481 |
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NCBI chr 7:138,460,259...138,589,996
Ensembl chr 7:138,460,259...138,589,996
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TRIM63 |
tripartite motif containing 63 |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of TRIM63 mRNA; Fenofibrate results in increased expression of TRIM63 protein Lovastatin promotes the reaction [Fenofibrate results in increased expression of TRIM63 protein]; PPARA protein affects the reaction [Fenofibrate results in increased expression of TRIM63 mRNA] |
CTD |
PMID:33408297 |
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NCBI chr 1:26,051,301...26,067,630
Ensembl chr 1:26,051,301...26,068,436
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G |
TRIP12 |
thyroid hormone receptor interactor 12 |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of TRIP12 mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of TRIP12 mRNA] |
CTD |
PMID:21318169 |
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NCBI chr 2:229,763,837...229,923,186
Ensembl chr 2:229,763,837...229,923,239
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G |
TXNIP |
thioredoxin interacting protein |
increases expression |
ISO EXP |
Fenofibrate results in increased expression of TXNIP mRNA |
CTD |
PMID:17264098 PMID:25572481 |
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NCBI chr 1:145,992,435...145,996,579
Ensembl chr 1:145,992,435...145,996,579
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TXNRD1 |
thioredoxin reductase 1 |
increases expression |
EXP |
Fenofibrate results in increased expression of TXNRD1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr12:104,215,779...104,350,307
Ensembl chr12:104,215,779...104,350,307
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TYR |
tyrosinase |
multiple interactions decreases expression |
ISO |
[Fenofibrate results in decreased chemical synthesis of Melanins] which results in decreased expression of TYR; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Fenofibrate results in decreased expression of TYR protein]; Fenofibrate results in decreased expression of and results in decreased activity of TYR protein Fenofibrate results in decreased expression of TYR mRNA |
CTD |
PMID:23872139 |
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NCBI chr11:89,177,875...89,295,759
Ensembl chr11:89,177,875...89,295,759
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G |
UBA5 |
ubiquitin like modifier activating enzyme 5 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of UBA5 mRNA |
CTD |
PMID:21318169 |
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NCBI chr 3:132,654,430...132,679,794
Ensembl chr 3:132,654,446...132,679,794
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UBE2G2 |
ubiquitin conjugating enzyme E2 G2 |
affects expression |
ISO |
Fenofibrate affects the expression of UBE2G2 mRNA |
CTD |
PMID:25596134 |
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NCBI chr21:44,768,580...44,801,820
Ensembl chr21:44,768,580...44,801,826
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UBE2Q2 |
ubiquitin conjugating enzyme E2 Q2 |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of UBE2Q2 mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of UBE2Q2 mRNA] |
CTD |
PMID:21318169 |
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NCBI chr15:75,843,447...75,901,078
Ensembl chr15:75,843,307...75,901,078
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G |
UBE2R2 |
ubiquitin conjugating enzyme E2 R2 |
decreases expression multiple interactions |
ISO |
Fenofibrate results in decreased expression of UBE2R2 mRNA PPARA protein affects the reaction [Fenofibrate results in decreased expression of UBE2R2 mRNA] |
CTD |
PMID:21318169 |
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NCBI chr 9:33,815,168...33,920,399
Ensembl chr 9:33,817,160...33,920,399
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UBE2W |
ubiquitin conjugating enzyme E2 W |
increases expression |
ISO |
Fenofibrate results in increased expression of UBE2W mRNA |
CTD |
PMID:21318169 |
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NCBI chr 8:73,780,096...73,878,862
Ensembl chr 8:73,780,097...73,878,910
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G |
UBE3A |
ubiquitin protein ligase E3A |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of UBE3A mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of UBE3A mRNA] |
CTD |
PMID:21318169 |
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NCBI chr15:25,333,728...25,439,056
Ensembl chr15:25,333,728...25,439,051
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G |
UBR2 |
ubiquitin protein ligase E3 component n-recognin 2 |
multiple interactions increases expression |
ISO |
[PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of UBR2 mRNA Fenofibrate results in increased expression of UBR2 mRNA |
CTD |
PMID:21318169 |
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NCBI chr 6:42,564,029...42,693,505
Ensembl chr 6:42,564,029...42,693,505
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G |
UCP2 |
uncoupling protein 2 |
multiple interactions increases expression |
ISO EXP |
[Fenofibrate binds to and results in increased activity of PPARA protein] which results in increased expression of UCP2 mRNA; [Fenofibrate co-treated with Sodium Glutamate] results in increased expression of UCP2 mRNA PPARA protein promotes the reaction [Fenofibrate results in increased expression of UCP2 protein] Fenofibrate results in increased expression of UCP2 mRNA; Fenofibrate results in increased expression of UCP2 protein PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of UCP2 mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of UCP2 protein] |
CTD |
PMID:11341955 PMID:16595124 PMID:21999347 PMID:24752549 PMID:32741897 |
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NCBI chr11:73,974,672...73,983,202
Ensembl chr11:73,974,061...73,982,843
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UCP3 |
uncoupling protein 3 |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of UCP3 mRNA fenofibrate co-treated with fructose increases expression of Ucp3 mRNA in liver and muscle fenofibrate increases expression of Ucp3 mRNA in muscle |
CTD RGD |
PMID:16595124 PMID:11934685 PMID:11934685 |
RGD:628329, RGD:628329 |
NCBI chr11:74,000,277...74,009,085
Ensembl chr11:74,000,277...74,009,085
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UGT1A1 |
UDP glucuronosyltransferase family 1 member A1 |
increases expression |
EXP |
Fenofibrate results in increased expression of UGT1A1 mRNA |
CTD |
PMID:25572481 |
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NCBI chr 2:233,760,270...233,773,300
Ensembl chr 2:233,760,270...233,773,300
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UGT1A3 |
UDP glucuronosyltransferase family 1 member A3 |
increases expression |
EXP |
Fenofibrate results in increased expression of UGT1A3 mRNA |
CTD |
PMID:17058234 |
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NCBI chr 2:233,729,042...233,773,300
Ensembl chr 2:233,729,042...233,773,300
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UGT1A6 |
UDP glucuronosyltransferase family 1 member A6 |
multiple interactions increases expression |
ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of UGT1A6 mRNA Fenofibrate results in increased expression of UGT1A6 mRNA |
CTD |
PMID:18253720 PMID:18775883 |
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NCBI chr 2:233,691,702...233,773,300
Ensembl chr 2:233,691,607...233,773,300
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UGT2B4 |
UDP glucuronosyltransferase family 2 member B4 |
increases expression |
EXP |
Fenofibrate results in increased expression of UGT2B4 mRNA |
CTD |
PMID:17058234 |
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NCBI chr 4:69,480,165...69,526,014
Ensembl chr 4:69,480,165...69,526,014
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URAD |
ureidoimidazoline (2-oxo-4-hydroxy-4-carboxy-5-) decarboxylase |
increases expression |
ISO |
Fenofibrate results in increased expression of URAD mRNA |
CTD |
PMID:32741897 |
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NCBI chr13:27,977,717...27,988,693
Ensembl chr13:27,977,717...27,988,693
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URI1 |
URI1 prefoldin like chaperone |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of URI1 mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of URI1 mRNA] |
CTD |
PMID:21318169 |
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NCBI chr19:29,923,657...30,016,612
Ensembl chr19:29,923,644...30,016,612
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URM1 |
ubiquitin related modifier 1 |
decreases expression multiple interactions |
ISO |
Fenofibrate results in decreased expression of URM1 mRNA PPARA protein affects the reaction [Fenofibrate results in decreased expression of URM1 mRNA] |
CTD |
PMID:21318169 |
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NCBI chr 9:128,371,319...128,392,016
Ensembl chr 9:128,371,361...128,392,016
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USP1 |
ubiquitin specific peptidase 1 |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of USP1 mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of USP1 mRNA] |
CTD |
PMID:21318169 |
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NCBI chr 1:62,436,395...62,451,804
Ensembl chr 1:62,436,297...62,451,804
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USP10 |
ubiquitin specific peptidase 10 |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of USP10 mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of USP10 mRNA] |
CTD |
PMID:21318169 |
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NCBI chr16:84,700,000...84,779,922
Ensembl chr16:84,699,986...84,779,922
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USP22 |
ubiquitin specific peptidase 22 |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of USP22 mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of USP22 mRNA] |
CTD |
PMID:21318169 |
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NCBI chr17:20,999,596...21,043,419
Ensembl chr17:20,999,596...21,043,760
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USP3 |
ubiquitin specific peptidase 3 |
increases expression |
ISO |
Fenofibrate results in increased expression of USP3 mRNA |
CTD |
PMID:25596134 |
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NCBI chr15:63,504,593...63,594,633
Ensembl chr15:63,504,511...63,594,640
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USP36 |
ubiquitin specific peptidase 36 |
decreases expression multiple interactions |
ISO |
Fenofibrate results in decreased expression of USP36 mRNA PPARA protein affects the reaction [Fenofibrate results in decreased expression of USP36 mRNA] |
CTD |
PMID:21318169 |
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NCBI chr17:78,787,381...78,841,439
Ensembl chr17:78,787,381...78,841,441
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USP38 |
ubiquitin specific peptidase 38 |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of USP38 mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of USP38 mRNA] |
CTD |
PMID:21318169 |
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NCBI chr 4:143,184,917...143,223,874
Ensembl chr 4:143,184,917...143,225,212
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USP4 |
ubiquitin specific peptidase 4 |
increases expression |
ISO |
Fenofibrate results in increased expression of USP4 mRNA |
CTD |
PMID:32741897 |
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NCBI chr 3:49,277,144...49,340,053
Ensembl chr 3:49,277,144...49,340,712
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USP7 |
ubiquitin specific peptidase 7 |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of USP7 mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of USP7 mRNA] |
CTD |
PMID:21318169 |
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NCBI chr16:8,892,097...8,963,906
Ensembl chr16:8,892,097...8,975,328
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USP9X |
ubiquitin specific peptidase 9 X-linked |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of USP9X mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of USP9X mRNA] |
CTD |
PMID:21318169 |
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NCBI chr X:41,085,445...41,236,579
Ensembl chr X:41,085,445...41,236,579
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USPL1 |
ubiquitin specific peptidase like 1 |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of USPL1 mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of USPL1 mRNA] |
CTD |
PMID:21318169 |
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NCBI chr13:30,617,920...30,660,766
Ensembl chr13:30,617,693...30,660,770
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VARS1 |
valyl-tRNA synthetase 1 |
increases expression |
ISO EXP |
Fenofibrate results in increased expression of VARS1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 6:31,777,518...31,795,752
Ensembl chr 6:31,777,518...31,795,752
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VCAM1 |
vascular cell adhesion molecule 1 |
multiple interactions |
ISO EXP |
Fenofibrate inhibits the reaction [Lipopolysaccharides results in increased expression of VCAM1 mRNA] dorsomorphin inhibits the reaction [Fenofibrate inhibits the reaction [ALB protein modified form results in increased expression of VCAM1 mRNA]]; Fenofibrate inhibits the reaction [ALB protein modified form results in increased expression of VCAM1 mRNA] |
CTD |
PMID:20580385 PMID:21300114 |
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NCBI chr 1:100,719,742...100,739,045
Ensembl chr 1:100,719,742...100,739,045
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VCPIP1 |
valosin containing protein interacting protein 1 |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of VCPIP1 mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of VCPIP1 mRNA] |
CTD |
PMID:21318169 |
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NCBI chr 8:66,628,487...66,667,231
Ensembl chr 8:66,628,487...66,667,231
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VEGFA |
vascular endothelial growth factor A |
multiple interactions |
ISO |
Fenofibrate inhibits the reaction [AHR protein affects the reaction [AGT protein results in increased expression of VEGFA protein]] |
CTD |
PMID:31016362 |
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NCBI chr 6:43,770,211...43,786,487
Ensembl chr 6:43,770,184...43,786,487
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VEGFB |
vascular endothelial growth factor B |
increases expression |
ISO |
Fenofibrate results in increased expression of VEGFB mRNA |
CTD |
PMID:17264098 PMID:25596134 |
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NCBI chr11:64,234,584...64,239,264
Ensembl chr11:64,234,584...64,239,264
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VNN1 |
vanin 1 |
increases expression |
ISO EXP |
Fenofibrate results in increased expression of VNN1 mRNA |
CTD |
PMID:11798191 PMID:25572481 PMID:27665778 PMID:32741897 |
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NCBI chr 6:132,680,849...132,714,055
Ensembl chr 6:132,680,849...132,714,055
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VSIR |
V-set immunoregulatory receptor |
decreases expression |
EXP |
Fenofibrate results in decreased expression of VSIR mRNA |
CTD |
PMID:25572481 |
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NCBI chr10:71,747,556...71,773,520
Ensembl chr10:71,747,556...71,773,520
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VWA8 |
von Willebrand factor A domain containing 8 |
increases expression |
ISO |
Fenofibrate results in increased expression of VWA8 mRNA |
CTD |
PMID:32741897 |
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NCBI chr13:41,566,835...41,961,109
Ensembl chr13:41,566,835...41,961,120
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WSB1 |
WD repeat and SOCS box containing 1 |
decreases expression multiple interactions |
ISO |
Fenofibrate results in decreased expression of WSB1 mRNA PPARA protein affects the reaction [Fenofibrate results in decreased expression of WSB1 mRNA] |
CTD |
PMID:21318169 |
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NCBI chr17:27,294,114...27,315,926
Ensembl chr17:27,294,076...27,315,926
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WSB2 |
WD repeat and SOCS box containing 2 |
increases expression |
ISO |
Fenofibrate results in increased expression of WSB2 mRNA |
CTD |
PMID:21318169 |
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NCBI chr12:118,032,687...118,062,174
Ensembl chr12:118,032,687...118,062,430
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WWC2 |
WW and C2 domain containing 2 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of WWC2 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 4:183,099,257...183,320,777
Ensembl chr 4:183,099,257...183,320,777
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XBP1 |
X-box binding protein 1 |
affects activity decreases expression |
ISO EXP |
Fenofibrate affects the activity of XBP1 protein Fenofibrate results in decreased expression of XBP1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr22:28,794,560...28,800,569
Ensembl chr22:28,794,555...28,800,597
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XPC |
XPC complex subunit, DNA damage recognition and repair factor |
decreases expression |
ISO |
Fenofibrate results in decreased expression of XPC mRNA |
CTD |
PMID:25596134 |
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NCBI chr 3:14,145,147...14,178,601
Ensembl chr 3:14,145,145...14,178,621
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XRCC5 |
X-ray repair cross complementing 5 |
multiple interactions increases expression |
ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of XRCC5 mRNA Fenofibrate results in increased expression of XRCC5 mRNA |
CTD |
PMID:17264098 PMID:18253720 PMID:18775883 |
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NCBI chr 2:216,109,348...216,206,293
Ensembl chr 2:216,107,464...216,206,303
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YARS1 |
tyrosyl-tRNA synthetase 1 |
increases expression |
EXP ISO |
Fenofibrate results in increased expression of YARS1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 1:32,775,239...32,817,358
Ensembl chr 1:32,775,237...32,818,031
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G |
ZNF385D |
zinc finger protein 385D |
increases expression |
EXP |
Fenofibrate results in increased expression of ZNF385D mRNA |
CTD |
PMID:25572481 |
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NCBI chr 3:21,412,218...22,372,763
Ensembl chr 3:21,412,218...22,373,321
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