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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:fenofibrate
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Accession:CHEBI:5001 term browser browse the term
Definition:A chlorobenzophenone that is (4-chlorophenyl)(phenyl)methanone substituted by a [2-methyl-1-oxo-1-(propan-2-yloxy)propan-2-yl]oxy group at position 1 on the phenyl ring.
Synonyms:exact_synonym: propan-2-yl 2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropanoate
 related_synonym: 2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic acid 1-methylethyl ester;   Antara;   FNF;   Finofibrate;   Formula=C20H21ClO4;   InChI=1S/C20H21ClO4/c1-13(2)24-19(23)20(3,4)25-17-11-7-15(8-12-17)18(22)14-5-9-16(21)10-6-14/h5-13H,1-4H3;   InChIKey=YMTINGFKWWXKFG-UHFFFAOYSA-N;   Isopropyl (4'-(p-chlorobenzoyl)-2-phenoxy-2-methyl)propionate;   Isopropyl 2-(4-(4-chlorobenzoyl)phenoxy)-2-methylpropionate;   Lipantil;   Lipofen;   Procetofen;   SMILES=CC(C)OC(=O)C(C)(C)Oc1ccc(cc1)C(=O)c1ccc(Cl)cc1;   Tricor;   Triglide
 xref: CAS:49562-28-9;   Chemspider:3222;   DrugBank:DB01039;   Drug_Central:1152;   HMDB:HMDB0015173;   KEGG:C07586;   KEGG:D00565;   LINCS:LSM-3107
 xref_mesh: MESH:D011345
 xref: PMID:17449930;   PMID:18212815;   PMID:23603800;   PMID:32675219;   PMID:33704429;   PMID:34244236;   PMID:34515330;   Patent:DE2250327;   Patent:US4058552;   Reaxys:2062462;   Wikipedia:Fenofibrate



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fenofibrate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A1BG alpha-1-B glycoprotein decreases expression ISO Fenofibrate results in decreased expression of A1BG protein CTD PMID:20118634 NCBI chr19:58,345,183...58,353,492
Ensembl chr19:58,345,178...58,353,492
JBrowse link
G AADAC arylacetamide deacetylase increases expression EXP Fenofibrate results in increased expression of AADAC mRNA CTD PMID:25572481 NCBI chr 3:151,814,116...151,828,488
Ensembl chr 3:151,814,073...151,828,488
JBrowse link
G AARS1 alanyl-tRNA synthetase 1 increases expression ISO Fenofibrate results in increased expression of AARS1 mRNA CTD PMID:25596134 NCBI chr16:70,252,298...70,289,506
Ensembl chr16:70,251,983...70,289,707
JBrowse link
G ABCA1 ATP binding cassette subfamily A member 1 increases expression EXP
ISO
Fenofibrate results in increased expression of ABCA1 mRNA; Fenofibrate results in increased expression of ABCA1 protein CTD PMID:19201410 NCBI chr 9:104,781,006...104,928,155
Ensembl chr 9:104,781,006...104,928,155
JBrowse link
G ABCB1 ATP binding cassette subfamily B member 1 multiple interactions EXP Fenofibrate inhibits the reaction [ABCB1 protein results in increased transport of Vincristine] CTD PMID:16316932 NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323
JBrowse link
G ABCB11 ATP binding cassette subfamily B member 11 multiple interactions
decreases expression
decreases activity
EXP
ISO
Fenofibrate inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid]
Fenofibrate results in decreased expression of ABCB11 mRNA
Fenofibrate results in decreased activity of ABCB11 protein
CTD PMID:20829430 PMID:23956101 PMID:24014644 PMID:27765674 NCBI chr 2:168,915,390...169,031,324
Ensembl chr 2:168,915,498...169,031,324
JBrowse link
G ABCB4 ATP binding cassette subfamily B member 4 increases expression ISO
EXP
Fenofibrate results in increased expression of ABCB4 mRNA CTD PMID:17118139 PMID:19118567 NCBI chr 7:87,365,896...87,476,027
Ensembl chr 7:87,401,696...87,480,435
JBrowse link
G ABCB6 ATP binding cassette subfamily B member 6 (LAN blood group) decreases expression ISO Fenofibrate results in decreased expression of ABCB6 mRNA CTD PMID:25596134 NCBI chr 2:219,209,772...219,218,958
Ensembl chr 2:219,209,772...219,218,994
JBrowse link
G ABCB9 ATP binding cassette subfamily B member 9 increases expression ISO Fenofibrate results in increased expression of ABCB9 mRNA CTD PMID:25596134 NCBI chr12:122,918,610...122,975,114
Ensembl chr12:122,920,951...122,981,649
JBrowse link
G ABCC2 ATP binding cassette subfamily C member 2 increases expression ISO Fenofibrate results in increased expression of ABCC2 mRNA CTD PMID:27765674 NCBI chr10:99,782,640...99,852,594
Ensembl chr10:99,782,640...99,852,594
JBrowse link
G ABCC3 ATP binding cassette subfamily C member 3 decreases expression ISO Fenofibrate results in decreased expression of ABCC3 mRNA CTD PMID:25596134 NCBI chr17:50,634,881...50,692,253
Ensembl chr17:50,634,777...50,692,253
JBrowse link
G ABCC4 ATP binding cassette subfamily C member 4 (PEL blood group) increases expression ISO Fenofibrate results in increased expression of ABCC4 mRNA CTD PMID:27765674 NCBI chr13:95,019,835...95,301,451
Ensembl chr13:95,019,835...95,301,475
JBrowse link
G ABCD3 ATP binding cassette subfamily D member 3 increases expression ISO Fenofibrate results in increased expression of ABCD3 mRNA CTD PMID:17118139 NCBI chr 1:94,385,131...94,518,663
Ensembl chr 1:94,418,389...94,518,666
JBrowse link
G ABCG1 ATP binding cassette subfamily G member 1 increases expression ISO Fenofibrate results in increased expression of ABCG1 mRNA CTD PMID:25596134 NCBI chr21:42,199,689...42,297,244
Ensembl chr21:42,199,689...42,304,389
JBrowse link
G ABCG5 ATP binding cassette subfamily G member 5 increases expression ISO Fenofibrate results in increased expression of ABCG5 mRNA CTD PMID:27765674 NCBI chr 2:43,806,211...43,839,231
Ensembl chr 2:43,812,472...43,838,865
JBrowse link
G ABCG8 ATP binding cassette subfamily G member 8 increases expression ISO Fenofibrate results in increased expression of ABCG8 mRNA CTD PMID:27765674 NCBI chr 2:43,838,971...43,882,988
Ensembl chr 2:43,831,942...43,882,988
JBrowse link
G ABHD4 abhydrolase domain containing 4, N-acyl phospholipase B increases expression ISO Fenofibrate results in increased expression of ABHD4 mRNA CTD PMID:25596134 NCBI chr14:22,598,300...22,612,963
Ensembl chr14:22,598,290...22,612,963
JBrowse link
G ABI3BP ABI family member 3 binding protein decreases expression EXP Fenofibrate results in decreased expression of ABI3BP mRNA CTD PMID:25572481 NCBI chr 3:100,749,156...100,993,421
Ensembl chr 3:100,749,156...100,993,515
JBrowse link
G ACAA1 acetyl-CoA acyltransferase 1 affects expression
increases expression
multiple interactions
ISO
EXP
Fenofibrate affects the expression of ACAA1A mRNA
Fenofibrate results in increased expression of ACAA1 mRNA
Fenofibrate results in increased expression of ACAA1 mRNA; Fenofibrate results in increased expression of ACAA1A mRNA
Fenofibrate promotes the reaction [Pyrazinamide results in increased expression of ACAA1 mRNA]; Pyrazinamide promotes the reaction [Fenofibrate results in increased expression of ACAA1 mRNA]
CTD PMID:20801182 PMID:24752549 PMID:27071702 PMID:32741897 NCBI chr 3:38,122,715...38,137,127
Ensembl chr 3:38,103,129...38,137,242
JBrowse link
G ACAA2 acetyl-CoA acyltransferase 2 affects expression
increases expression
ISO
EXP
Fenofibrate affects the expression of ACAA2 mRNA
Fenofibrate results in increased expression of ACAA2 mRNA
Fenofibrate results in increased expression of ACAA2 mRNA; Fenofibrate results in increased expression of ACAA2 protein
CTD PMID:20118634 PMID:20801182 PMID:25572481 PMID:27665778 PMID:32741897 NCBI chr18:49,782,164...49,813,533
Ensembl chr18:49,782,164...49,813,953
JBrowse link
G ACACA acetyl-CoA carboxylase alpha multiple interactions
decreases expression
increases expression
ISO
EXP
NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACACA mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACACA mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACACA mRNA]
Fenofibrate inhibits the reaction [Dietary Fats results in increased expression of ACACA mRNA]
Fenofibrate inhibits the reaction [[Fructose co-treated with Palmitic Acid] results in decreased expression of ACACA protein modified form]; Fenofibrate inhibits the reaction [[Fructose co-treated with Palmitic Acid] results in increased expression of ACACA protein]
Fenofibrate results in decreased expression of ACACA protein
CTD PMID:23063693 PMID:24752549 PMID:32730863 PMID:38216941 NCBI chr17:37,084,992...37,406,836
Ensembl chr17:37,084,992...37,406,836
JBrowse link
G ACACB acetyl-CoA carboxylase beta multiple interactions
increases expression
ISO NR1H2 gene mutant form affects the reaction [Fenofibrate results in increased expression of ACACB mRNA]; NR1H3 gene mutant form affects the reaction [Fenofibrate results in increased expression of ACACB mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACACB mRNA] CTD PMID:17118139 PMID:23063693 NCBI chr12:109,111,189...109,268,226
Ensembl chr12:109,116,587...109,268,226
JBrowse link
G ACADL acyl-CoA dehydrogenase long chain increases expression ISO Fenofibrate results in increased expression of ACADL mRNA CTD PMID:17690133 NCBI chr 2:210,187,923...210,225,447
Ensembl chr 2:210,187,126...210,225,447
JBrowse link
G ACADM acyl-CoA dehydrogenase medium chain increases expression
multiple interactions
ISO
EXP
Fenofibrate results in increased expression of ACADM mRNA
PPARA protein affects the reaction [Fenofibrate results in increased expression of ACADM mRNA]
CTD PMID:11798191 PMID:17690133 PMID:19124612 PMID:24752549 PMID:25572481 More... NCBI chr 1:75,724,709...75,763,679
Ensembl chr 1:75,724,431...75,787,575
JBrowse link
G ACADS acyl-CoA dehydrogenase short chain multiple interactions ISO Fenofibrate inhibits the reaction [ACADS protein affects the cleavage of CASP3 protein]; Fenofibrate inhibits the reaction [tert-Butylhydroperoxide results in decreased expression of ACADS mRNA]; Fenofibrate inhibits the reaction [tert-Butylhydroperoxide results in decreased expression of and results in decreased activity of ACADS protein] CTD PMID:26989860 NCBI chr12:120,725,826...120,740,008
Ensembl chr12:120,725,774...120,740,008
JBrowse link
G ACADVL acyl-CoA dehydrogenase very long chain increases expression ISO
EXP
Fenofibrate results in increased expression of ACADVL mRNA CTD PMID:17118139 PMID:24752549 PMID:27665778 NCBI chr17:7,217,125...7,225,266
Ensembl chr17:7,217,125...7,225,266
JBrowse link
G ACAT1 acetyl-CoA acetyltransferase 1 multiple interactions
increases expression
ISO
EXP
[Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of ACAT1 mRNA
Fenofibrate results in increased expression of ACAT1 mRNA
CTD PMID:18253720 PMID:24752549 NCBI chr11:108,116,705...108,147,603
Ensembl chr11:108,116,695...108,148,957
JBrowse link
G ACLY ATP citrate lyase increases expression
multiple interactions
ISO Fenofibrate results in increased expression of ACLY mRNA
PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACLY mRNA]
CTD PMID:23063693 NCBI chr17:41,866,917...41,930,545
Ensembl chr17:41,866,917...41,930,542
JBrowse link
G ACO1 aconitase 1 increases expression ISO Fenofibrate results in increased expression of ACO1 mRNA CTD PMID:17264098 NCBI chr 9:32,384,643...32,454,769
Ensembl chr 9:32,384,603...32,454,769
JBrowse link
G ACO2 aconitase 2 increases expression EXP Fenofibrate results in increased expression of ACO2 mRNA CTD PMID:24752549 NCBI chr22:41,469,117...41,528,974
Ensembl chr22:41,447,830...41,529,273
JBrowse link
G ACOT1 acyl-CoA thioesterase 1 increases expression ISO Fenofibrate results in increased expression of ACOT1 mRNA CTD PMID:11798191 PMID:17690133 PMID:27665778 PMID:32741897 NCBI chr14:73,490,933...73,543,796
Ensembl chr14:73,537,143...73,543,796
JBrowse link
G ACOT2 acyl-CoA thioesterase 2 affects expression
multiple interactions
increases expression
ISO Fenofibrate affects the expression of ACOT2 mRNA
Fenofibrate results in increased expression of and results in increased activity of ACOT2 protein
Fenofibrate results in increased expression of ACOT2 mRNA
CTD PMID:16595124 PMID:20801182 PMID:27665778 PMID:32741897 NCBI chr14:73,567,620...73,575,658
Ensembl chr14:73,567,620...73,575,658
JBrowse link
G ACOT4 acyl-CoA thioesterase 4 increases expression ISO Fenofibrate results in increased expression of ACOT4 mRNA CTD PMID:27665778 PMID:32741897 NCBI chr14:73,591,873...73,595,766
Ensembl chr14:73,591,873...73,595,766
JBrowse link
G ACOT7 acyl-CoA thioesterase 7 increases expression ISO Fenofibrate results in increased expression of ACOT7 mRNA CTD PMID:32741897 NCBI chr 1:6,264,272...6,393,767
Ensembl chr 1:6,264,269...6,393,767
JBrowse link
G ACOX1 acyl-CoA oxidase 1 affects expression
multiple interactions
increases expression
ISO
EXP
Fenofibrate affects the expression of ACOX1 mRNA
[Fenofibrate co-treated with Fatty Acids, Nonesterified] results in increased expression of ACOX1 protein; [Fenofibrate co-treated with Oleic Acid] results in increased expression of ACOX1 mRNA; Fenofibrate inhibits the reaction [Fatty Acids, Nonesterified results in decreased expression of ACOX1 mRNA]; Fenofibrate inhibits the reaction [Fatty Acids, Nonesterified results in decreased expression of ACOX1 protein]; Fenofibrate promotes the reaction [Fatty Acids, Nonesterified results in increased expression of ACOX1 mRNA]; PPARA protein promotes the reaction [Fenofibrate results in increased expression of ACOX1 protein]
Fenofibrate results in increased expression of ACOX1 mRNA; Fenofibrate results in increased expression of ACOX1 protein
Fenofibrate inhibits the reaction [Zoledronic Acid results in decreased expression of ACOX1 mRNA]; NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACOX1 mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACOX1 mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACOX1 mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACOX1 protein]
[Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of ACOX1 mRNA
CTD PMID:16707586 PMID:17118139 PMID:17690133 PMID:18253720 PMID:18775883 More... NCBI chr17:75,941,507...75,979,166
Ensembl chr17:75,941,507...75,979,177
JBrowse link
G ACOX2 acyl-CoA oxidase 2 multiple interactions ISO Fenofibrate inhibits the reaction [zoledronic acid results in decreased expression of ACOX2 mRNA] CTD PMID:28871336 NCBI chr 3:58,505,136...58,537,190
Ensembl chr 3:58,505,136...58,537,283
JBrowse link
G ACSL1 acyl-CoA synthetase long chain family member 1 increases expression
multiple interactions
decreases expression
affects expression
ISO
EXP
Fenofibrate results in increased expression of ACSL1 mRNA; Fenofibrate results in increased expression of ACSL1 protein
PPARA protein promotes the reaction [Fenofibrate results in increased expression of ACSL1 protein]
PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACSL1 mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACSL1 protein]
Fenofibrate results in decreased expression of ACSL1 protein
Fenofibrate affects the expression of ACSL1 mRNA
CTD PMID:10600944 PMID:17118139 PMID:20118634 PMID:20801182 PMID:24752549 More... NCBI chr 4:184,755,595...184,826,594
Ensembl chr 4:184,755,595...184,826,818
JBrowse link
G ACSL3 acyl-CoA synthetase long chain family member 3 increases expression ISO Fenofibrate results in increased expression of ACSL3 mRNA CTD PMID:32741897 NCBI chr 2:222,861,036...222,944,639
Ensembl chr 2:222,860,942...222,944,639
JBrowse link
G ACSL4 acyl-CoA synthetase long chain family member 4 increases expression ISO Fenofibrate results in increased expression of ACSL4 mRNA CTD PMID:17118139 NCBI chr  X:109,641,335...109,733,257
Ensembl chr  X:109,624,244...109,733,403
JBrowse link
G ACSL5 acyl-CoA synthetase long chain family member 5 increases expression ISO Fenofibrate results in increased expression of ACSL5 mRNA CTD PMID:17118139 NCBI chr10:112,374,116...112,428,376
Ensembl chr10:112,374,116...112,428,379
JBrowse link
G ACSL6 acyl-CoA synthetase long chain family member 6 increases expression ISO Fenofibrate results in increased expression of ACSL6 mRNA CTD PMID:16595124 NCBI chr 5:131,949,973...132,012,213
Ensembl chr 5:131,949,973...132,012,243
JBrowse link
G ACSS2 acyl-CoA synthetase short chain family member 2 decreases expression EXP Fenofibrate results in decreased expression of ACSS2 mRNA CTD PMID:25572481 NCBI chr20:34,874,989...34,927,959
Ensembl chr20:34,872,146...34,927,962
JBrowse link
G ACTA2 actin alpha 2, smooth muscle multiple interactions ISO
EXP
Fenofibrate inhibits the reaction [zoledronic acid results in increased expression of ACTA2 protein]
Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 mRNA]
CTD PMID:28871336 PMID:32613381 NCBI chr10:88,935,074...88,991,337
Ensembl chr10:88,934,822...88,991,339
JBrowse link
G ADAM22 ADAM metallopeptidase domain 22 increases expression ISO Fenofibrate results in increased expression of ADAM22 mRNA CTD PMID:32741897 NCBI chr 7:87,934,251...88,202,889
Ensembl chr 7:87,934,143...88,202,889
JBrowse link
G ADCY1 adenylate cyclase 1 decreases expression EXP Fenofibrate results in decreased expression of ADCY1 mRNA CTD PMID:25596134 NCBI chr 7:45,574,140...45,723,116
Ensembl chr 7:45,574,140...45,723,116
JBrowse link
G ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide decreases expression EXP Fenofibrate results in decreased expression of ADH1C mRNA CTD PMID:25572481 NCBI chr 4:99,336,497...99,352,746
Ensembl chr 4:99,336,497...99,352,746
JBrowse link
G ADH4 alcohol dehydrogenase 4 (class II), pi polypeptide decreases expression EXP Fenofibrate results in decreased expression of ADH4 mRNA CTD PMID:25572481 NCBI chr 4:99,123,658...99,144,297
Ensembl chr 4:99,123,657...99,157,792
JBrowse link
G ADIPOQ adiponectin, C1Q and collagen domain containing increases expression
multiple interactions
EXP Fenofibrate results in increased expression of ADIPOQ protein
[candesartan co-treated with Fenofibrate] results in increased expression of ADIPOQ protein; Fenofibrate inhibits the reaction [Fatty Acids, Nonesterified results in decreased expression of ADIPOQ protein]
CTD PMID:16443859 PMID:24735863 NCBI chr 3:186,842,710...186,858,463
Ensembl chr 3:186,842,704...186,858,463
JBrowse link
G ADIPOR2 adiponectin receptor 2 increases expression ISO Fenofibrate results in increased expression of ADIPOR2 mRNA CTD PMID:16306350 NCBI chr12:1,691,070...1,788,674
Ensembl chr12:1,688,574...1,788,674
JBrowse link
G AGRN agrin decreases expression ISO Fenofibrate results in decreased expression of AGRN mRNA CTD PMID:25596134 NCBI chr 1:1,020,120...1,056,116
Ensembl chr 1:1,020,120...1,056,119
JBrowse link
G AGT angiotensinogen multiple interactions ISO Fenofibrate affects the reaction [[AHR protein affects the susceptibility to AGT protein] which affects the expression of EDN1 mRNA]; Fenofibrate affects the reaction [[AHR protein affects the susceptibility to AGT protein] which affects the expression of JUN mRNA]; Fenofibrate inhibits the reaction [AHR protein affects the reaction [AGT protein results in increased expression of COL1A1 mRNA]]; Fenofibrate inhibits the reaction [AHR protein affects the reaction [AGT protein results in increased expression of COL3A1 mRNA]]; Fenofibrate inhibits the reaction [AHR protein affects the reaction [AGT protein results in increased expression of VEGFA protein]] CTD PMID:31016362 NCBI chr 1:230,702,523...230,745,583
Ensembl chr 1:230,690,776...230,745,576
JBrowse link
G AGXT2 alanine--glyoxylate aminotransferase 2 decreases expression EXP Fenofibrate results in decreased expression of AGXT2 mRNA CTD PMID:25572481 NCBI chr 5:34,998,102...35,047,949
Ensembl chr 5:34,998,101...35,048,135
JBrowse link
G AHR aryl hydrocarbon receptor affects activity
multiple interactions
EXP
ISO
Fenofibrate affects the activity of AHR protein
Fenofibrate affects the reaction [[AHR protein affects the susceptibility to AGT protein] which affects the expression of EDN1 mRNA]; Fenofibrate affects the reaction [[AHR protein affects the susceptibility to AGT protein] which affects the expression of JUN mRNA]; Fenofibrate inhibits the reaction [AHR protein affects the reaction [AGT protein results in increased expression of COL1A1 mRNA]]; Fenofibrate inhibits the reaction [AHR protein affects the reaction [AGT protein results in increased expression of COL3A1 mRNA]]; Fenofibrate inhibits the reaction [AHR protein affects the reaction [AGT protein results in increased expression of VEGFA protein]]
CTD PMID:25596134 PMID:31016362 NCBI chr 7:17,298,652...17,346,147
Ensembl chr 7:16,916,359...17,346,152
JBrowse link
G AIFM2 AIF family member 2 increases expression ISO
EXP
Fenofibrate results in increased expression of AIFM2 mRNA CTD PMID:25596134 NCBI chr10:70,112,271...70,132,825
Ensembl chr10:70,098,223...70,132,934
JBrowse link
G AIG1 androgen induced 1 increases expression ISO Fenofibrate results in increased expression of AIG1 mRNA CTD PMID:32741897 NCBI chr 6:143,059,213...143,343,883
Ensembl chr 6:143,060,496...143,341,058
JBrowse link
G AK4 adenylate kinase 4 affects expression ISO Fenofibrate affects the expression of AK4 mRNA CTD PMID:25596134 NCBI chr 1:65,147,552...65,232,145
Ensembl chr 1:65,147,549...65,232,145
JBrowse link
G AKR1B10 aldo-keto reductase family 1 member B10 multiple interactions
decreases activity
EXP Fenofibrate inhibits the reaction [AKR1B10 protein results in increased reduction of Daunorubicin]; Fenofibrate inhibits the reaction [AKR1B10 protein results in increased reduction of Glyceraldehyde]
Fenofibrate results in decreased activity of AKR1B10 protein; Fenofibrate results in decreased activity of AKR1B10 protein mutant form
CTD PMID:18325492 PMID:19028477 NCBI chr 7:134,527,567...134,541,412
Ensembl chr 7:134,527,567...134,541,412
JBrowse link
G AKR1C2 aldo-keto reductase family 1 member C2 increases expression EXP Fenofibrate results in increased expression of AKR1C2 mRNA CTD PMID:25596134 NCBI chr10:4,987,775...5,018,000
Ensembl chr10:4,987,775...5,018,031
JBrowse link
G ALB albumin multiple interactions EXP
ISO
dorsomorphin inhibits the reaction [Fenofibrate inhibits the reaction [ALB protein modified form results in increased expression of ICAM1 mRNA]]; dorsomorphin inhibits the reaction [Fenofibrate inhibits the reaction [ALB protein modified form results in increased expression of SELE mRNA]]; dorsomorphin inhibits the reaction [Fenofibrate inhibits the reaction [ALB protein modified form results in increased expression of VCAM1 mRNA]]; Fenofibrate inhibits the reaction [ALB protein modified form results in increased degradation of NFKBIA protein]; Fenofibrate inhibits the reaction [ALB protein modified form results in increased expression of ICAM1 mRNA]; Fenofibrate inhibits the reaction [ALB protein modified form results in increased expression of NFKB1 protein]; Fenofibrate inhibits the reaction [ALB protein modified form results in increased expression of RELA protein]; Fenofibrate inhibits the reaction [ALB protein modified form results in increased expression of SELE mRNA]; Fenofibrate inhibits the reaction [ALB protein modified form results in increased expression of VCAM1 mRNA]; PRKAA1 protein affects the reaction [Fenofibrate results in decreased susceptibility to ALB protein modified form]
Fenofibrate inhibits the reaction [tyloxapol results in decreased expression of ALB mRNA]
CTD PMID:20580385 PMID:37076581 NCBI chr 4:73,404,287...73,421,482
Ensembl chr 4:73,397,114...73,421,482
JBrowse link
G ALDH1A2 aldehyde dehydrogenase 1 family member A2 increases expression ISO Fenofibrate results in increased expression of ALDH1A2 mRNA CTD PMID:17118139 NCBI chr15:57,953,429...58,065,711
Ensembl chr15:57,953,424...58,497,866
JBrowse link
G ALDH6A1 aldehyde dehydrogenase 6 family member A1 increases expression EXP Fenofibrate results in increased expression of ALDH6A1 mRNA CTD PMID:24752549 NCBI chr14:74,056,847...74,084,453
Ensembl chr14:74,056,847...74,084,492
JBrowse link
G ALDOA aldolase, fructose-bisphosphate A increases expression ISO Fenofibrate results in increased expression of ALDOA mRNA CTD PMID:25596134 NCBI chr16:30,064,279...30,070,420
Ensembl chr16:30,064,164...30,070,457
JBrowse link
G ALOX12 arachidonate 12-lipoxygenase, 12S type increases expression EXP Fenofibrate results in increased expression of ALOX12 mRNA CTD PMID:12759900 NCBI chr17:6,996,049...7,010,754
Ensembl chr17:6,996,049...7,010,754
JBrowse link
G ALPK2 alpha kinase 2 increases expression EXP Fenofibrate results in increased expression of ALPK2 mRNA CTD PMID:25572481 NCBI chr18:58,481,247...58,629,091
Ensembl chr18:58,481,247...58,629,091
JBrowse link
G ALPL alkaline phosphatase, biomineralization associated decreases expression EXP Fenofibrate results in decreased expression of ALPL mRNA CTD PMID:25572481 NCBI chr 1:21,508,984...21,578,410
Ensembl chr 1:21,509,397...21,578,410
JBrowse link
G ANAPC11 anaphase promoting complex subunit 11 multiple interactions
decreases expression
ISO PPARA protein affects the reaction [Fenofibrate results in decreased expression of ANAPC11 mRNA] CTD PMID:21318169 NCBI chr17:81,890,790...81,900,533
Ensembl chr17:81,890,790...81,900,991
JBrowse link
G ANGPTL4 angiopoietin like 4 increases expression ISO
EXP
Fenofibrate results in increased expression of ANGPTL4 mRNA CTD PMID:17118139 PMID:25572481 PMID:25596134 PMID:27665778 PMID:32741897 NCBI chr19:8,364,155...8,374,370
Ensembl chr19:8,363,289...8,374,370
JBrowse link
G ANKRA2 ankyrin repeat family A member 2 increases expression EXP Fenofibrate results in increased expression of ANKRA2 mRNA CTD PMID:25596134 NCBI chr 5:73,552,190...73,565,639
Ensembl chr 5:73,552,190...73,565,667
JBrowse link
G ANXA3 annexin A3 decreases expression ISO Fenofibrate results in decreased expression of ANXA3 protein CTD PMID:20118634 NCBI chr 4:78,551,770...78,610,447
Ensembl chr 4:78,551,747...78,610,451
JBrowse link
G APEX1 apurinic/apyrimidinic endodeoxyribonuclease 1 multiple interactions
increases expression
ISO [Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of APEX1 mRNA
Fenofibrate results in increased expression of APEX1 mRNA
CTD PMID:17264098 PMID:18253720 PMID:18775883 NCBI chr14:20,455,226...20,457,767
Ensembl chr14:20,455,191...20,457,772
JBrowse link
G APOA1 apolipoprotein A1 decreases expression
multiple interactions
EXP
ISO
Fenofibrate results in decreased expression of APOA1 mRNA; Fenofibrate results in decreased expression of APOA1 protein
[Fenofibrate co-treated with Pyrazinamide] results in increased expression of APOA1 mRNA
Fenofibrate promotes the reaction [APOA1 protein results in increased secretion of Lipids]; PPARA protein affects the reaction [Fenofibrate promotes the reaction [APOA1 protein results in increased secretion of Lipids]]
Fenofibrate promotes the reaction [APOA1 protein results in increased secretion of Lipids]; PPARA protein inhibits the reaction [Fenofibrate results in decreased expression of APOA1 mRNA]
CTD PMID:7983038 PMID:19201410 PMID:19445040 PMID:27071702 NCBI chr11:116,835,751...116,837,622
Ensembl chr11:116,835,751...116,837,622
JBrowse link
G APOA4 apolipoprotein A4 decreases expression ISO Fenofibrate results in decreased expression of APOA4 mRNA CTD PMID:11798191 NCBI chr11:116,820,700...116,823,304
Ensembl chr11:116,820,700...116,823,304
JBrowse link
G APOB apolipoprotein B decreases expression EXP Fenofibrate results in decreased expression of APOB protein CTD PMID:21411093 NCBI chr 2:21,001,429...21,044,073
Ensembl chr 2:21,001,429...21,044,073
JBrowse link
G APOC3 apolipoprotein C3 affects expression
decreases expression
ISO
EXP
Fenofibrate affects the expression of APOC3 mRNA
Fenofibrate results in decreased expression of APOC3 mRNA; Fenofibrate results in decreased expression of APOC3 protein
CTD PMID:8847480 PMID:10799317 PMID:20801182 PMID:24752549 NCBI chr11:116,829,907...116,833,072
Ensembl chr11:116,829,706...116,833,072
JBrowse link
G APP amyloid beta precursor protein multiple interactions EXP Fenofibrate affects the reaction [PSEN1 protein affects the cleavage of APP protein] CTD PMID:17962197 NCBI chr21:25,880,550...26,171,128
Ensembl chr21:25,880,535...26,171,128
JBrowse link
G AQP3 aquaporin 3 (Gill blood group) increases expression ISO Fenofibrate results in increased expression of AQP3 mRNA CTD PMID:32741897 NCBI chr 9:33,441,160...33,447,593
Ensembl chr 9:33,441,156...33,447,596
JBrowse link
G AQP7 aquaporin 7 increases expression ISO Fenofibrate results in increased expression of AQP7 mRNA CTD PMID:32741897 NCBI chr 9:33,383,191...33,402,568
Ensembl chr 9:33,383,179...33,402,682
JBrowse link
G AQP9 aquaporin 9 decreases expression EXP Fenofibrate results in decreased expression of AQP9 mRNA CTD PMID:25572481 NCBI chr15:58,138,169...58,185,911
Ensembl chr15:58,138,169...58,185,911
JBrowse link
G ARFGEF2 ARF guanine nucleotide exchange factor 2 increases expression
decreases expression
EXP
ISO
Fenofibrate results in increased expression of ARFGEF2 mRNA
Fenofibrate results in decreased expression of ARFGEF2 mRNA
CTD PMID:25596134 NCBI chr20:48,921,711...49,036,693
Ensembl chr20:48,921,711...49,036,693
JBrowse link
G ARHGEF10 Rho guanine nucleotide exchange factor 10 decreases expression ISO Fenofibrate results in decreased expression of ARHGEF10 mRNA CTD PMID:25596134 NCBI chr 8:1,823,300...1,958,641
Ensembl chr 8:1,823,926...1,958,641
JBrowse link
G ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 increases expression
multiple interactions
ISO Fenofibrate results in increased expression of ARIH1 mRNA
PPARA protein affects the reaction [Fenofibrate results in increased expression of ARIH1 mRNA]
CTD PMID:21318169 NCBI chr15:72,474,330...72,602,987
Ensembl chr15:72,474,330...72,602,987
JBrowse link
G ARL1 ARF like GTPase 1 decreases expression ISO Fenofibrate results in decreased expression of ARL1 mRNA CTD PMID:25596134 NCBI chr12:101,393,116...101,407,820
Ensembl chr12:101,393,116...101,407,772
JBrowse link
G ASB6 ankyrin repeat and SOCS box containing 6 multiple interactions
increases expression
ISO [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of ASB6 mRNA
Fenofibrate results in increased expression of ASB6 mRNA
CTD PMID:21318169 NCBI chr 9:129,634,605...129,642,151
Ensembl chr 9:129,634,604...129,642,169
JBrowse link
G ASNS asparagine synthetase (glutamine-hydrolyzing) increases expression ISO
EXP
Fenofibrate results in increased expression of ASNS mRNA CTD PMID:25596134 NCBI chr 7:97,851,677...97,928,441
Ensembl chr 7:97,851,677...97,872,542
JBrowse link
G ATE1 arginyltransferase 1 increases expression
multiple interactions
ISO Fenofibrate results in increased expression of ATE1 mRNA
PPARA protein affects the reaction [Fenofibrate results in increased expression of ATE1 mRNA]
CTD PMID:21318169 NCBI chr10:121,740,424...121,928,463
Ensembl chr10:121,709,393...121,928,801
JBrowse link
G ATF3 activating transcription factor 3 multiple interactions
increases expression
ISO
EXP
[Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of ATF3 mRNA
Fenofibrate results in increased expression of ATF3 mRNA
CTD PMID:18978307 PMID:25596134 NCBI chr 1:212,565,407...212,620,777
Ensembl chr 1:212,565,334...212,620,777
JBrowse link
G ATF4 activating transcription factor 4 affects activity
multiple interactions
EXP
ISO
Fenofibrate affects the activity of ATF4 protein
Fenofibrate inhibits the reaction [Dietary Fats results in increased expression of ATF4 mRNA]; Fenofibrate inhibits the reaction [Dietary Fats results in increased expression of ATF4 protein]
CTD PMID:25596134 PMID:38216941 NCBI chr22:39,520,559...39,522,686
Ensembl chr22:39,519,695...39,522,686
JBrowse link
G ATF6 activating transcription factor 6 multiple interactions ISO Fenofibrate inhibits the reaction [Dietary Fats results in increased expression of ATF6 mRNA]; Fenofibrate inhibits the reaction [Dietary Fats results in increased expression of ATF6 protein] CTD PMID:38216941 NCBI chr 1:161,766,320...161,964,070
Ensembl chr 1:161,766,298...161,977,574
JBrowse link
G ATG12 autophagy related 12 increases expression
multiple interactions
ISO Fenofibrate results in increased expression of ATG12 mRNA
PPARA protein affects the reaction [Fenofibrate results in increased expression of ATG12 mRNA]
CTD PMID:21318169 NCBI chr 5:115,828,200...115,841,565
Ensembl chr 5:115,828,200...115,841,837
JBrowse link
G ATG7 autophagy related 7 increases expression
multiple interactions
ISO Fenofibrate results in increased expression of ATG7 mRNA
Fenofibrate inhibits the reaction [tyloxapol results in decreased expression of ATG7 protein]; PPARA protein affects the reaction [Fenofibrate results in increased expression of ATG7 mRNA]
CTD PMID:21318169 PMID:36905866 NCBI chr 3:11,272,397...11,576,353
Ensembl chr 3:11,272,309...11,557,665
JBrowse link
G ATOSA atos homolog A decreases expression ISO Fenofibrate results in decreased expression of ATOSA mRNA CTD PMID:25596134 NCBI chr15:52,581,321...52,709,815
Ensembl chr15:52,581,317...52,709,817
JBrowse link
G ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 decreases expression ISO Fenofibrate results in decreased expression of ATP2A2 protein CTD PMID:20118634 NCBI chr12:110,280,616...110,351,093
Ensembl chr12:110,280,756...110,351,093
JBrowse link
G ATP2B4 ATPase plasma membrane Ca2+ transporting 4 increases expression EXP Fenofibrate results in increased expression of ATP2B4 mRNA CTD PMID:25572481 NCBI chr 1:203,626,832...203,744,081
Ensembl chr 1:203,626,832...203,744,081
JBrowse link
G BAX BCL2 associated X, apoptosis regulator multiple interactions ISO Fenofibrate inhibits the reaction [tert-Butylhydroperoxide results in increased expression of BAX protein] CTD PMID:26989860 NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798
JBrowse link
G BCAR3 BCAR3 adaptor protein, NSP family member decreases expression ISO Fenofibrate results in decreased expression of BCAR3 mRNA CTD PMID:25596134 NCBI chr 1:93,561,741...93,848,151
Ensembl chr 1:93,561,741...93,847,150
JBrowse link
G BCAT1 branched chain amino acid transaminase 1 decreases expression EXP Fenofibrate results in decreased expression of BCAT1 mRNA CTD PMID:25596134 NCBI chr12:24,810,024...24,949,340
Ensembl chr12:24,810,024...24,949,101
JBrowse link
G BCAT2 branched chain amino acid transaminase 2 increases expression EXP Fenofibrate results in increased expression of BCAT2 mRNA CTD PMID:25596134 NCBI chr19:48,795,064...48,811,029
Ensembl chr19:48,795,062...48,811,029
JBrowse link
G BCKDK branched chain keto acid dehydrogenase kinase decreases activity ISO Fenofibrate results in decreased activity of BCKDK protein CTD PMID:19819289 NCBI chr16:31,108,386...31,117,640
Ensembl chr16:31,106,107...31,112,791
JBrowse link
G BCL2 BCL2 apoptosis regulator decreases expression
multiple interactions
EXP
ISO
Fenofibrate results in decreased expression of BCL2 mRNA
Fenofibrate inhibits the reaction [tert-Butylhydroperoxide results in decreased expression of BCL2 protein]
CTD PMID:15843896 PMID:26989860 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128
JBrowse link
G BCL2A1 BCL2 related protein A1 decreases expression EXP Fenofibrate results in decreased expression of BCL2A1 mRNA CTD PMID:20520642 NCBI chr15:79,960,892...79,971,196
Ensembl chr15:79,960,892...79,971,196
JBrowse link
G BCL2L1 BCL2 like 1 decreases expression EXP Fenofibrate results in decreased expression of BCL2L1 mRNA CTD PMID:20520642 NCBI chr20:31,664,452...31,723,963
Ensembl chr20:31,664,452...31,723,989
JBrowse link
G BCL3 BCL3 transcription coactivator decreases expression EXP Fenofibrate results in decreased expression of BCL3 mRNA CTD PMID:25596134 NCBI chr19:44,747,705...44,760,044
Ensembl chr19:44,747,705...44,760,044
JBrowse link
G BCR BCR activator of RhoGEF and GTPase multiple interactions ISO [Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of BCR mRNA CTD PMID:18253720 NCBI chr22:23,180,509...23,318,037
Ensembl chr22:23,179,704...23,318,037
JBrowse link
G BDH1 3-hydroxybutyrate dehydrogenase 1 decreases expression ISO Fenofibrate results in decreased expression of BDH1 protein CTD PMID:20118634 NCBI chr 3:197,509,783...197,573,343
Ensembl chr 3:197,509,783...197,573,323
JBrowse link
G BECN1 beclin 1 multiple interactions ISO Fenofibrate inhibits the reaction [tyloxapol results in decreased expression of BECN1 protein] CTD PMID:36905866 NCBI chr17:42,810,132...42,824,282
Ensembl chr17:42,810,134...42,833,350
JBrowse link
G BHLHE40 basic helix-loop-helix family member e40 decreases expression EXP
ISO
Fenofibrate results in decreased expression of BHLHE40 mRNA CTD PMID:25596134 NCBI chr 3:4,979,437...4,985,323
Ensembl chr 3:4,979,437...4,985,323
JBrowse link
G BIRC3 baculoviral IAP repeat containing 3 decreases expression EXP Fenofibrate results in decreased expression of BIRC3 mRNA CTD PMID:20520642 NCBI chr11:102,317,484...102,339,403
Ensembl chr11:102,317,484...102,339,403
JBrowse link
G BMF Bcl2 modifying factor increases expression
decreases expression
EXP
ISO
Fenofibrate results in increased expression of BMF mRNA
Fenofibrate results in decreased expression of BMF mRNA
CTD PMID:25572481 PMID:25596134 NCBI chr15:40,087,890...40,108,879
Ensembl chr15:40,087,890...40,108,892
JBrowse link
G BNIP3 BCL2 interacting protein 3 increases expression ISO Fenofibrate results in increased expression of BNIP3 mRNA CTD PMID:25596134 NCBI chr10:131,967,684...131,981,923
Ensembl chr10:131,967,684...131,981,967
JBrowse link
G BRAP BRCA1 associated protein affects expression
multiple interactions
ISO Fenofibrate affects the expression of BRAP mRNA
PPARA protein affects the reaction [Fenofibrate affects the expression of BRAP mRNA]
CTD PMID:21318169 NCBI chr12:111,642,146...111,685,956
Ensembl chr12:111,642,146...111,685,956
JBrowse link
G BRCC3 BRCA1/BRCA2-containing complex subunit 3 increases expression
multiple interactions
ISO Fenofibrate results in increased expression of BRCC3 mRNA
[PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of BRCC3 mRNA
CTD PMID:21318169 NCBI chr  X:155,071,508...155,123,077
Ensembl chr  X:155,071,420...155,123,077
JBrowse link
G BRD2 bromodomain containing 2 decreases expression ISO Fenofibrate results in decreased expression of BRD2 mRNA CTD PMID:25596134 NCBI chr 6:32,968,594...32,981,505
Ensembl chr 6:32,968,594...32,981,505
JBrowse link
G BTG2 BTG anti-proliferation factor 2 affects expression ISO Fenofibrate affects the expression of BTG2 mRNA CTD PMID:25596134 NCBI chr 1:203,305,519...203,309,602
Ensembl chr 1:203,305,491...203,309,602
JBrowse link
G C19orf12 chromosome 19 open reading frame 12 increases expression EXP Fenofibrate results in increased expression of C19ORF12 mRNA CTD PMID:25572481 NCBI chr19:29,698,886...29,715,789
Ensembl chr19:29,698,937...29,715,789
JBrowse link
G C9 complement C9 decreases expression ISO Fenofibrate results in decreased expression of C9 mRNA CTD PMID:11798191 NCBI chr 5:39,284,140...39,364,495
Ensembl chr 5:39,284,140...39,371,324
JBrowse link
G CA9 carbonic anhydrase 9 multiple interactions EXP Fenofibrate inhibits the reaction [Oxygen deficiency results in increased expression of CA9 mRNA]; Fenofibrate inhibits the reaction [Oxygen deficiency results in increased expression of CA9 protein] CTD PMID:34520103 NCBI chr 9:35,673,928...35,681,159
Ensembl chr 9:35,673,928...35,681,159
JBrowse link
G CACNA2D3 calcium voltage-gated channel auxiliary subunit alpha2delta 3 increases expression ISO Fenofibrate results in increased expression of CACNA2D3 mRNA CTD PMID:32741897 NCBI chr 3:54,122,552...55,074,557
Ensembl chr 3:54,122,552...55,074,557
JBrowse link
G CALM1 calmodulin 1 affects expression ISO Fenofibrate affects the expression of CALM1 mRNA CTD PMID:20801182 NCBI chr14:90,396,502...90,408,268
Ensembl chr14:90,396,502...90,408,268
JBrowse link
G CANX calnexin increases expression
multiple interactions
ISO Fenofibrate results in increased expression of CANX mRNA
PPARA protein affects the reaction [Fenofibrate results in increased expression of CANX mRNA]
CTD PMID:21318169 NCBI chr 5:179,678,656...179,731,641
Ensembl chr 5:179,678,628...179,731,641
JBrowse link
G CASP3 caspase 3 increases cleavage
multiple interactions
decreases expression
EXP
ISO
Fenofibrate results in increased cleavage of CASP3 protein
Fenofibrate inhibits the reaction [Cyclophosphamide results in increased cleavage of CASP3 protein]
[ESR1 protein results in increased susceptibility to Estradiol] inhibits the reaction [Fenofibrate results in decreased expression of CASP3 protein]; Fenofibrate inhibits the reaction [[Fructose co-treated with Palmitic Acid] results in increased activity of CASP3 protein]
[Fenofibrate co-treated with Pioglitazone] inhibits the reaction [Doxorubicin results in increased expression of CASP3 protein]; Fenofibrate inhibits the reaction [ACADS protein affects the cleavage of CASP3 protein]; Fenofibrate inhibits the reaction [Doxorubicin results in increased expression of CASP3 protein]; Fenofibrate inhibits the reaction [tert-Butylhydroperoxide results in increased cleavage of CASP3 protein]
CTD PMID:20520642 PMID:26989860 PMID:29134746 PMID:32730863 PMID:36988379 More... NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062
JBrowse link
G CASP4 caspase 4 increases expression ISO Fenofibrate results in increased expression of CASP4 mRNA CTD PMID:17264098 NCBI chr11:104,942,866...104,968,574
Ensembl chr11:104,942,866...104,969,366
JBrowse link
G CAT catalase multiple interactions
increases expression
increases activity
ISO [Fenofibrate co-treated with Diethylnitrosamine] results in increased activity of CAT protein; [Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of CAT mRNA
Fenofibrate inhibits the reaction [Cyclophosphamide results in decreased activity of CAT protein]
Fenofibrate results in increased expression of CAT mRNA
Fenofibrate results in increased activity of CAT protein
CTD PMID:17264098 PMID:18253720 PMID:38278497 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060
JBrowse link
G CAV1 caveolin 1 increases expression EXP Fenofibrate results in increased expression of CAV1 mRNA CTD PMID:15314095 NCBI chr 7:116,525,009...116,561,185
Ensembl chr 7:116,524,994...116,561,179
JBrowse link
G CBLB Cbl proto-oncogene B increases expression
multiple interactions
ISO Fenofibrate results in increased expression of CBLB mRNA
PPARA protein affects the reaction [Fenofibrate results in increased expression of CBLB mRNA]
CTD PMID:21318169 NCBI chr 3:105,655,461...105,869,449
Ensembl chr 3:105,655,461...105,869,552
JBrowse link
G CCDC34 coiled-coil domain containing 34 increases expression ISO Fenofibrate results in increased expression of CCDC34 mRNA CTD PMID:32741897 NCBI chr11:27,338,512...27,363,215
Ensembl chr11:27,330,827...27,363,234
JBrowse link
G CCDC90B coiled-coil domain containing 90B increases expression ISO Fenofibrate results in increased expression of CCDC90B mRNA CTD PMID:25596134 NCBI chr11:83,259,081...83,286,367
Ensembl chr11:83,259,081...83,286,390
JBrowse link
G CCL13 C-C motif chemokine ligand 13 increases expression EXP Fenofibrate results in increased expression of CCL13 mRNA CTD PMID:25572481 NCBI chr17:34,356,480...34,358,610
Ensembl chr17:34,356,480...34,358,610
JBrowse link
G CCL2 C-C motif chemokine ligand 2 multiple interactions
decreases expression
EXP
ISO
Fenofibrate inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein]; Fenofibrate inhibits the reaction [Glucose results in increased expression of CCL2 mRNA]; Fenofibrate inhibits the reaction [Glucose results in increased expression of CCL2 protein]; Fenofibrate inhibits the reaction [Glucose results in increased secretion of CCL2 protein]
Fenofibrate results in decreased expression of CCL2 mRNA; Fenofibrate results in decreased expression of CCL2 protein
Fenofibrate inhibits the reaction [Lipopolysaccharides results in increased expression of CCL2 mRNA]; Fenofibrate inhibits the reaction [Lipopolysaccharides results in increased secretion of CCL2 protein]
CTD PMID:15968640 PMID:16306350 PMID:16600694 PMID:18356826 PMID:19132243 More... NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208
JBrowse link
G CCL5 C-C motif chemokine ligand 5 multiple interactions EXP Fenofibrate inhibits the reaction [Chenodeoxycholic Acid results in increased expression of CCL5 mRNA]; Fenofibrate inhibits the reaction [Chenodeoxycholic Acid results in increased expression of CCL5 protein]; Fenofibrate inhibits the reaction [TNF protein results in increased expression of CCL5 mRNA]; Fenofibrate inhibits the reaction [TNF protein results in increased expression of CCL5 protein] CTD PMID:12126966 PMID:12586603 NCBI chr17:35,871,491...35,880,360
Ensembl chr17:35,871,491...35,880,793
JBrowse link
G CCN1 cellular communication network factor 1 decreases expression EXP Fenofibrate results in decreased expression of CCN1 mRNA CTD PMID:25572481 NCBI chr 1:85,580,761...85,583,950
Ensembl chr 1:85,580,761...85,584,589
JBrowse link
G CCND1 cyclin D1 decreases expression
multiple interactions
increases expression
EXP
ISO
Fenofibrate results in decreased expression of CCND1 mRNA; Fenofibrate results in decreased expression of CCND1 protein
ESR1 protein inhibits the reaction [Fenofibrate results in increased expression of CCND1 protein]; Estradiol inhibits the reaction [Fenofibrate results in increased expression of CCND1 protein]
Fenofibrate results in increased expression of CCND1 mRNA
[Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of CCND1 mRNA
CTD PMID:16569247 PMID:17264098 PMID:18253720 PMID:18978307 PMID:20520642 More... NCBI chr11:69,641,156...69,654,474
Ensembl chr11:69,641,156...69,654,474
JBrowse link
G CCNF cyclin F increases expression ISO Fenofibrate results in increased expression of CCNF mRNA CTD PMID:32741897 NCBI chr16:2,429,447...2,458,854
Ensembl chr16:2,429,394...2,458,854
JBrowse link
G CCNG2 cyclin G2 decreases expression
increases expression
EXP
ISO
Fenofibrate results in decreased expression of CCNG2 mRNA
Fenofibrate results in increased expression of CCNG2 mRNA
CTD PMID:25596134 NCBI chr 4:77,157,207...77,170,060
Ensembl chr 4:77,157,207...77,433,388
JBrowse link
G CCNT1 cyclin T1 multiple interactions ISO Fenofibrate affects the reaction [[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CCNT1 mRNA]; Fenofibrate affects the reaction [[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CCNT1 protein] CTD PMID:20828602 NCBI chr12:48,688,458...48,716,707
Ensembl chr12:48,688,458...48,716,998
JBrowse link
G CD14 CD14 molecule increases expression EXP Fenofibrate results in increased expression of CD14 mRNA CTD PMID:25572481 NCBI chr 5:140,631,732...140,633,701
Ensembl chr 5:140,631,728...140,633,700
JBrowse link
G CD36 CD36 molecule (CD36 blood group) increases expression
multiple interactions
ISO
EXP
Fenofibrate results in increased expression of CD36 mRNA
Fenofibrate inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of CD36 mRNA]
CTD PMID:16707586 PMID:17118139 PMID:25572481 PMID:32613381 NCBI chr 7:80,602,207...80,679,274
Ensembl chr 7:80,369,575...80,679,277
JBrowse link
G CD40 CD40 molecule decreases expression EXP Fenofibrate results in decreased expression of CD40 mRNA CTD PMID:20520642 NCBI chr20:46,118,314...46,129,858
Ensembl chr20:46,118,271...46,129,863
JBrowse link
G CD40LG CD40 ligand multiple interactions
decreases expression
EXP candesartan promotes the reaction [Fenofibrate results in decreased expression of CD40LG protein]; Fenofibrate promotes the reaction [candesartan results in decreased expression of CD40LG protein] CTD PMID:16443859 NCBI chr  X:136,648,158...136,660,390
Ensembl chr  X:136,648,158...136,660,390
JBrowse link
G CDC25A cell division cycle 25A increases expression ISO Fenofibrate results in increased expression of CDC25A mRNA CTD PMID:17264098 NCBI chr 3:48,157,146...48,188,417
Ensembl chr 3:48,157,146...48,188,417
JBrowse link
G CDK20 cyclin dependent kinase 20 increases expression EXP Fenofibrate results in increased expression of CDK20 mRNA CTD PMID:25572481 NCBI chr 9:87,966,441...87,974,533
Ensembl chr 9:87,966,441...87,974,753
JBrowse link
G CDK9 cyclin dependent kinase 9 multiple interactions ISO Fenofibrate affects the reaction [[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CDK9 mRNA]; Fenofibrate affects the reaction [[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CDK9 protein] CTD PMID:20828602 NCBI chr 9:127,786,034...127,790,792
Ensembl chr 9:127,785,679...127,790,792
JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A multiple interactions
decreases expression
ISO [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of CDKN1A mRNA
Fenofibrate results in decreased expression of CDKN1A mRNA
CTD PMID:18253720 PMID:25596134 NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,397
JBrowse link
G CDKN1B cyclin dependent kinase inhibitor 1B multiple interactions
decreases expression
ISO
EXP
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of CDKN1B mRNA
ESR1 protein inhibits the reaction [Fenofibrate results in decreased expression of CDKN1B protein]; Estradiol inhibits the reaction [Fenofibrate results in decreased expression of CDKN1B protein]
CTD PMID:18253720 PMID:29134746 NCBI chr12:12,717,368...12,722,369
Ensembl chr12:12,685,498...12,722,369
JBrowse link
G CEP128 centrosomal protein 128 increases expression ISO Fenofibrate results in increased expression of CEP128 mRNA CTD PMID:32741897 NCBI chr14:80,476,969...80,959,502
Ensembl chr14:80,476,983...80,959,517
JBrowse link
G CERS5 ceramide synthase 5 decreases expression ISO Fenofibrate results in decreased expression of CERS5 mRNA CTD PMID:25596134 NCBI chr12:50,129,289...50,167,369
Ensembl chr12:50,129,289...50,167,533
JBrowse link
G CES1 carboxylesterase 1 multiple interactions ISO [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of CES1 mRNA CTD PMID:18253720 NCBI chr16:55,802,851...55,833,096
Ensembl chr16:55,802,851...55,833,337
JBrowse link
G CHEK1 checkpoint kinase 1 increases expression ISO Fenofibrate results in increased expression of CHEK1 mRNA CTD PMID:17264098 NCBI chr11:125,625,136...125,681,124
Ensembl chr11:125,625,163...125,676,255
JBrowse link
G CHEK2 checkpoint kinase 2 multiple interactions ISO [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of CHEK2 mRNA CTD PMID:18253720 NCBI chr22:28,687,743...28,741,834
Ensembl chr22:28,687,743...28,742,422
JBrowse link
G CHID1 chitinase domain containing 1 decreases expression ISO Fenofibrate results in decreased expression of CHID1 mRNA CTD PMID:11798191 NCBI chr11:867,859...915,214
Ensembl chr11:867,859...915,058
JBrowse link
G CHRNA2 cholinergic receptor nicotinic alpha 2 subunit increases expression ISO Fenofibrate results in increased expression of CHRNA2 mRNA CTD PMID:32741897 NCBI chr 8:27,459,756...27,479,261
Ensembl chr 8:27,459,756...27,479,883
JBrowse link
G CHST8 carbohydrate sulfotransferase 8 multiple interactions ISO [Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of CHST8 mRNA CTD PMID:18253720 NCBI chr19:33,621,953...33,773,509
Ensembl chr19:33,621,953...33,773,509
JBrowse link
G CISH cytokine inducible SH2 containing protein decreases expression
multiple interactions
ISO Fenofibrate results in decreased expression of CISH mRNA
PPARA protein affects the reaction [Fenofibrate results in decreased expression of CISH mRNA]
CTD PMID:21318169 NCBI chr 3:50,606,489...50,611,774
Ensembl chr 3:50,606,489...50,611,774
JBrowse link
G CMBL carboxymethylenebutenolidase homolog increases expression ISO Fenofibrate results in increased expression of CMBL mRNA CTD PMID:25596134 NCBI chr 5:10,277,595...10,307,902
Ensembl chr 5:10,275,875...10,307,902
JBrowse link
G CNOT4 CCR4-NOT transcription complex subunit 4 multiple interactions
increases expression
ISO PPARA protein affects the reaction [Fenofibrate results in increased expression of CNOT4 mRNA] CTD PMID:21318169 NCBI chr 7:135,361,795...135,510,102
Ensembl chr 7:135,361,795...135,510,145
JBrowse link
G COL1A1 collagen type I alpha 1 chain multiple interactions EXP
ISO
Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]]
Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of COL1A1 mRNA]; Fenofibrate inhibits the reaction [AHR protein affects the reaction [AGT protein results in increased expression of COL1A1 mRNA]]; Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]; Fenofibrate inhibits the reaction [Zoledronic Acid results in increased expression of COL1A1 mRNA]; NR0B2 protein inhibits the reaction [Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of COL1A1 mRNA]]
CTD PMID:19593819 PMID:28871336 PMID:31016362 NCBI chr17:50,184,101...50,201,631
Ensembl chr17:50,184,101...50,201,632
JBrowse link
G COL3A1 collagen type III alpha 1 chain multiple interactions ISO Fenofibrate inhibits the reaction [AHR protein affects the reaction [AGT protein results in increased expression of COL3A1 mRNA]]; Fenofibrate inhibits the reaction [Zoledronic Acid results in increased expression of COL3A1 mRNA] CTD PMID:28871336 PMID:31016362 NCBI chr 2:188,974,373...189,012,746
Ensembl chr 2:188,974,373...189,012,746
JBrowse link
G COL4A1 collagen type IV alpha 1 chain multiple interactions ISO Fenofibrate inhibits the reaction [zoledronic acid results in increased expression of COL4A1 mRNA] CTD PMID:28871336 NCBI chr13:110,148,963...110,307,157
Ensembl chr13:110,148,963...110,307,202
JBrowse link
G COLQ collagen like tail subunit of asymmetric acetylcholinesterase increases expression ISO Fenofibrate results in increased expression of COLQ mRNA CTD PMID:27665778 PMID:32741897 NCBI chr 3:15,450,133...15,521,706
Ensembl chr 3:15,450,133...15,521,751
JBrowse link
G COQ7 coenzyme Q7, hydroxylase increases expression ISO Fenofibrate results in increased expression of COQ7 mRNA CTD PMID:16595124 NCBI chr16:19,067,614...19,083,097
Ensembl chr16:19,067,614...19,080,095
JBrowse link
G COX6B2 cytochrome c oxidase subunit 6B2 increases expression ISO Fenofibrate results in increased expression of COX6B2 mRNA CTD PMID:11798191 NCBI chr19:55,349,704...55,354,719
Ensembl chr19:55,349,306...55,354,719
JBrowse link
G CPT1A carnitine palmitoyltransferase 1A increases expression
multiple interactions
ISO
EXP
Fenofibrate results in increased expression of CPT1A mRNA
Fenofibrate inhibits the reaction [zoledronic acid results in decreased expression of CPT1A mRNA]
Fenofibrate affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA]; Fenofibrate inhibits the reaction [Fatty Acids, Nonesterified results in decreased expression of CPT1A protein]; Fenofibrate promotes the reaction [Fatty Acids, Nonesterified results in increased expression of CPT1A mRNA]; Fenofibrate promotes the reaction [Oleic Acid results in increased expression of CPT1A mRNA]
CTD PMID:16595124 PMID:17070643 PMID:17118139 PMID:19124612 PMID:24534255 More... NCBI chr11:68,754,620...68,844,277
Ensembl chr11:68,754,620...68,844,410
JBrowse link
G CPT1B carnitine palmitoyltransferase 1B affects expression
multiple interactions
increases expression
ISO Fenofibrate affects the expression of CPT1B mRNA
Fenofibrate inhibits the reaction [Pyrazinamide results in decreased expression of CPT1B mRNA]
Fenofibrate results in increased expression of CPT1B mRNA
CTD PMID:16595124 PMID:19395589 PMID:20801182 PMID:27071702 PMID:32741897 NCBI chr22:50,568,861...50,578,612
Ensembl chr22:50,568,861...50,578,465
JBrowse link
G CPT2 carnitine palmitoyltransferase 2 decreases expression
multiple interactions
increases expression
ISO
EXP
Fenofibrate results in decreased expression of CPT2 protein
Fenofibrate inhibits the reaction [zoledronic acid results in decreased expression of CPT2 mRNA]
Fenofibrate results in increased expression of CPT2 mRNA
[Oleic Acid co-treated with Fenofibrate] results in increased expression of CPT2 mRNA
CTD PMID:16595124 PMID:16707586 PMID:19395589 PMID:20118634 PMID:24534255 More... NCBI chr 1:53,196,824...53,214,197
Ensembl chr 1:53,196,792...53,214,197
JBrowse link
G CRAT carnitine O-acetyltransferase increases expression
increases activity
multiple interactions
ISO Fenofibrate results in increased expression of CRAT mRNA
Fenofibrate results in increased activity of CRAT protein
[Fenofibrate co-treated with Diethylnitrosamine] results in increased activity of CRAT protein; [Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of CRAT mRNA
CTD PMID:11798191 PMID:17264098 PMID:18253720 PMID:27665778 PMID:32741897 NCBI chr 9:129,094,794...129,110,793
Ensembl chr 9:129,094,142...129,111,189
JBrowse link
G CREB3L3 cAMP responsive element binding protein 3 like 3 increases expression EXP
ISO
Fenofibrate results in increased expression of CREB3L3 mRNA CTD PMID:25572481 PMID:32741897 NCBI chr19:4,153,631...4,173,054
Ensembl chr19:4,153,631...4,173,054
JBrowse link
G CROT carnitine O-octanoyltransferase increases expression ISO Fenofibrate results in increased expression of CROT mRNA CTD PMID:32741897 NCBI chr 7:87,345,664...87,399,794
Ensembl chr 7:87,345,664...87,399,794
JBrowse link
G CRP C-reactive protein multiple interactions
decreases expression
EXP candesartan promotes the reaction [Fenofibrate results in decreased expression of CRP protein]; Fenofibrate promotes the reaction [candesartan results in decreased expression of CRP protein] CTD PMID:16123850 PMID:16443859 NCBI chr 1:159,712,289...159,714,589
Ensembl chr 1:159,712,289...159,714,589
JBrowse link
G CSF1R colony stimulating factor 1 receptor decreases expression ISO Fenofibrate results in decreased expression of CSF1R mRNA CTD PMID:16707586 NCBI chr 5:150,053,295...150,113,365
Ensembl chr 5:150,053,291...150,113,372
JBrowse link
G CSF2 colony stimulating factor 2 multiple interactions ISO [Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of CSF2 mRNA CTD PMID:18253720 NCBI chr 5:132,073,789...132,076,170
Ensembl chr 5:132,073,789...132,076,170
JBrowse link
G CTH cystathionine gamma-lyase increases expression
decreases expression
EXP
ISO
Fenofibrate results in increased expression of CTH mRNA
Fenofibrate results in decreased expression of CTH mRNA
CTD PMID:25596134 NCBI chr 1:70,411,268...70,439,851
Ensembl chr 1:70,411,218...70,439,851
JBrowse link
G CTSC cathepsin C decreases expression ISO Fenofibrate results in decreased expression of CTSC mRNA CTD PMID:25596134 NCBI chr11:88,293,592...88,337,736
Ensembl chr11:88,265,069...88,359,684
JBrowse link
G CX3CL1 C-X3-C motif chemokine ligand 1 multiple interactions EXP Fenofibrate inhibits the reaction [Glucose results in increased expression of CX3CL1 mRNA]; Fenofibrate inhibits the reaction [Glucose results in increased expression of CX3CL1 protein] CTD PMID:19132243 NCBI chr16:57,372,490...57,385,044
Ensembl chr16:57,372,477...57,385,044
JBrowse link
G CYCS cytochrome c, somatic multiple interactions EXP Fenofibrate inhibits the reaction [[Fructose co-treated with Palmitic Acid] results in increased expression of CYCS protein] CTD PMID:32730863 NCBI chr 7:25,118,656...25,125,260
Ensembl chr 7:25,118,656...25,125,260
JBrowse link
G CYLD CYLD lysine 63 deubiquitinase decreases expression
multiple interactions
ISO Fenofibrate results in decreased expression of CYLD mRNA
PPARA protein affects the reaction [Fenofibrate results in decreased expression of CYLD mRNA]
CTD PMID:21318169 NCBI chr16:50,742,086...50,801,935
Ensembl chr16:50,742,050...50,801,935
JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 increases expression
decreases activity
ISO
EXP
Fenofibrate results in increased expression of CYP1A1 mRNA
Fenofibrate results in decreased activity of CYP1A1 protein
CTD PMID:19118567 PMID:33814510 NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536
JBrowse link
G CYP1A2 cytochrome P450 family 1 subfamily A member 2 multiple interactions
affects expression
ISO [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of CYP1A2 mRNA
Fenofibrate affects the expression of CYP1A2 mRNA
CTD PMID:18253720 PMID:20801182 PMID:25596134 NCBI chr15:74,748,845...74,756,607
Ensembl chr15:74,748,845...74,756,607
JBrowse link
G CYP1B1 cytochrome P450 family 1 subfamily B member 1 decreases activity EXP Fenofibrate results in decreased activity of CYP1B1 protein CTD PMID:33814510 NCBI chr 2:38,067,509...38,076,151
Ensembl chr 2:38,066,973...38,109,902
JBrowse link
G CYP2A7 cytochrome P450 family 2 subfamily A member 7 multiple interactions ISO [Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of CYP2A3 mRNA CTD PMID:18253720 NCBI chr19:40,875,439...40,882,231
Ensembl chr19:40,875,439...40,882,752
JBrowse link
G CYP2B6 cytochrome P450 family 2 subfamily B member 6 increases expression ISO Fenofibrate results in increased expression of CYP2B10 mRNA CTD PMID:11798191 NCBI chr19:40,991,282...41,018,398
Ensembl chr19:40,991,282...41,018,398
JBrowse link
G CYP2C18 cytochrome P450 family 2 subfamily C member 18 multiple interactions ISO [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of CYP2C mRNA CTD PMID:18253720 NCBI chr10:94,683,729...94,736,190
Ensembl chr10:94,683,729...94,736,190
JBrowse link
G CYP2C19 cytochrome P450 family 2 subfamily C member 19 increases expression EXP Fenofibrate results in increased expression of CYP2C19 mRNA CTD PMID:25572481 NCBI chr10:94,762,681...94,855,547
Ensembl chr10:94,762,681...94,855,547
JBrowse link
G CYP2C8 cytochrome P450 family 2 subfamily C member 8 decreases activity
affects expression
increases expression
EXP Fenofibrate results in decreased activity of CYP2C8 protein
Fenofibrate affects the expression of CYP2C8 protein
Fenofibrate results in increased expression of CYP2C8 mRNA
CTD PMID:15601807 PMID:25572481 PMID:29960002 NCBI chr10:95,036,772...95,069,497
Ensembl chr10:95,036,772...95,069,497
JBrowse link
G CYP2D6 cytochrome P450 family 2 subfamily D member 6 (gene/pseudogene) multiple interactions ISO [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of CYP2D22 mRNA CTD PMID:18253720 NCBI chr22:42,126,499...42,130,810
Ensembl chr22:42,126,499...42,130,865
JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 increases expression ISO Fenofibrate results in increased expression of CYP2E1 mRNA CTD PMID:19118567 NCBI chr10:133,527,363...133,539,123
Ensembl chr10:133,520,406...133,561,220
JBrowse link
G CYP2F1 cytochrome P450 family 2 subfamily F member 1 multiple interactions ISO [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of CYP2F2 mRNA CTD PMID:18253720 NCBI chr19:41,114,432...41,128,381
Ensembl chr19:41,114,432...41,128,381
JBrowse link
G CYP2J2 cytochrome P450 family 2 subfamily J member 2 affects expression EXP Fenofibrate affects the expression of CYP2J2 protein CTD PMID:29960002 NCBI chr 1:59,893,308...59,969,212
Ensembl chr 1:59,893,308...59,926,773
JBrowse link
G CYP3A5 cytochrome P450 family 3 subfamily A member 5 multiple interactions ISO [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of CYP3A13 mRNA CTD PMID:18253720 NCBI chr 7:99,648,194...99,679,996
Ensembl chr 7:99,648,194...99,679,996
JBrowse link
G CYP3A7 cytochrome P450 family 3 subfamily A member 7 increases expression EXP Fenofibrate results in increased expression of CYP3A7 mRNA CTD PMID:19118567 NCBI chr 7:99,705,036...99,735,196
Ensembl chr 7:99,705,036...99,735,196
JBrowse link
G CYP4A11 cytochrome P450 family 4 subfamily A member 11 increases expression EXP Fenofibrate results in increased expression of CYP4A11 mRNA CTD PMID:25572481 NCBI chr 1:46,929,188...46,941,476
Ensembl chr 1:46,929,177...46,941,484
JBrowse link
G CYP4A22 cytochrome P450 family 4 subfamily A member 22 increases expression
multiple interactions
affects expression
EXP
ISO
Fenofibrate results in increased expression of CYP4A22 mRNA
Fenofibrate results in increased expression of CYP4A1 mRNA
[Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of CYP4A1 mRNA
Fenofibrate affects the expression of CYP4A1 mRNA
CTD PMID:17264098 PMID:18775883 PMID:20801182 PMID:25572481 PMID:27665778 More... NCBI chr 1:47,137,441...47,149,727
Ensembl chr 1:47,137,435...47,149,727
JBrowse link
G CYP4B1 cytochrome P450 family 4 subfamily B member 1 multiple interactions ISO [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of CYP4B1 mRNA CTD PMID:18253720 NCBI chr 1:46,799,046...46,819,413
Ensembl chr 1:46,757,838...46,819,413
JBrowse link
G CYP4X1 cytochrome P450 family 4 subfamily X member 1 increases expression EXP Fenofibrate results in increased expression of CYP4X1 mRNA CTD PMID:25572481 NCBI chr 1:46,961,364...47,055,432
Ensembl chr 1:47,023,669...47,050,751
JBrowse link
G CYP7A1 cytochrome P450 family 7 subfamily A member 1 multiple interactions
decreases expression
ISO
EXP
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of CYP7A1 mRNA
Fenofibrate results in decreased expression of CYP7A1 mRNA
CTD PMID:14685799 PMID:18253720 NCBI chr 8:58,490,178...58,500,163
Ensembl chr 8:58,490,178...58,500,163
JBrowse link
G CYP7B1 cytochrome P450 family 7 subfamily B member 1 multiple interactions ISO [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of CYP7B1 mRNA CTD PMID:18253720 NCBI chr 8:64,586,575...64,798,737
Ensembl chr 8:64,587,763...64,798,737
JBrowse link
G CYP8B1 cytochrome P450 family 8 subfamily B member 1 multiple interactions
increases expression
ISO [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of CYP8B1 mRNA
Fenofibrate results in increased expression of CYP8B1 mRNA
CTD PMID:18253720 PMID:32741897 NCBI chr 3:42,872,192...42,875,879
Ensembl chr 3:42,856,005...42,875,898
JBrowse link
G DACT2 dishevelled binding antagonist of beta catenin 2 increases expression ISO Fenofibrate results in increased expression of DACT2 mRNA CTD PMID:27665778 NCBI chr 6:168,292,830...168,319,777
Ensembl chr 6:168,292,830...168,319,777
JBrowse link
G DBI diazepam binding inhibitor, acyl-CoA binding protein increases expression ISO Fenofibrate results in increased expression of DBI mRNA CTD PMID:17118139 NCBI chr 2:119,366,977...119,372,543
Ensembl chr 2:119,366,924...119,372,550
JBrowse link
G DCUN1D1 defective in cullin neddylation 1 domain containing 1 increases expression ISO Fenofibrate results in increased expression of DCUN1D1 mRNA CTD PMID:21318169 NCBI chr 3:182,938,074...182,985,918
Ensembl chr 3:182,938,074...182,985,953
JBrowse link
G DDIT3 DNA damage inducible transcript 3 increases expression EXP Fenofibrate results in increased expression of DDIT3 mRNA CTD PMID:25596134 NCBI chr12:57,516,588...57,520,517
Ensembl chr12:57,516,588...57,521,737
JBrowse link
G DDIT4 DNA damage inducible transcript 4 decreases expression
increases expression
EXP
ISO
Fenofibrate results in decreased expression of DDIT4 mRNA
Fenofibrate results in increased expression of DDIT4 mRNA
CTD PMID:25596134 NCBI chr10:72,273,924...72,276,036
Ensembl chr10:72,273,919...72,276,036
JBrowse link
G DDX24 DEAD-box helicase 24 decreases expression ISO Fenofibrate results in decreased expression of DDX24 mRNA CTD PMID:25596134 NCBI chr14:94,048,287...94,081,202
Ensembl chr14:94,048,287...94,081,202
JBrowse link
G DECR1 2,4-dienoyl-CoA reductase 1 increases expression
affects expression
ISO Fenofibrate results in increased expression of DECR1 mRNA
Fenofibrate results in increased expression of DECR1 mRNA; Fenofibrate results in increased expression of DECR1 protein
Fenofibrate affects the expression of DECR1 mRNA
CTD PMID:11798191 PMID:20118634 PMID:20801182 PMID:27665778 PMID:32741897 NCBI chr 8:90,001,477...90,053,633
Ensembl chr 8:90,001,405...90,053,633
JBrowse link
G DECR2 2,4-dienoyl-CoA reductase 2 increases expression ISO Fenofibrate results in increased expression of DECR2 mRNA CTD PMID:27665778 NCBI chr16:401,885...412,482
Ensembl chr16:401,858...412,487
JBrowse link
G DHX37 DEAH-box helicase 37 increases expression EXP Fenofibrate results in increased expression of DHX37 mRNA CTD PMID:25596134 NCBI chr12:124,946,826...124,989,131
Ensembl chr12:124,946,825...124,989,131
JBrowse link
G DMD dystrophin decreases expression ISO Fenofibrate results in decreased expression of DMD mRNA CTD PMID:11798191 NCBI chr  X:31,119,222...33,339,388
Ensembl chr  X:31,097,677...33,339,609
JBrowse link
G DNAJA2 DnaJ heat shock protein family (Hsp40) member A2 multiple interactions
increases expression
ISO [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of DNAJA2 mRNA
Fenofibrate results in increased expression of DNAJA2 mRNA
PPARA protein affects the reaction [Fenofibrate results in increased expression of DNAJA2 mRNA]
CTD PMID:18253720 PMID:21318169 NCBI chr16:46,955,362...46,973,674
Ensembl chr16:46,955,362...46,973,674
JBrowse link
G DNAJA3 DnaJ heat shock protein family (Hsp40) member A3 increases expression ISO Fenofibrate results in increased expression of DNAJA3 mRNA CTD PMID:21318169 NCBI chr16:4,425,868...4,456,775
Ensembl chr16:4,425,805...4,456,775
JBrowse link
G DNAJB1 DnaJ heat shock protein family (Hsp40) member B1 multiple interactions ISO [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of DNAJB1 mRNA CTD PMID:18253720 NCBI chr19:14,514,769...14,560,391
Ensembl chr19:14,513,789...14,560,391
JBrowse link
G DNAJB4 DnaJ heat shock protein family (Hsp40) member B4 decreases expression
multiple interactions
ISO Fenofibrate results in decreased expression of DNAJB4 mRNA
PPARA protein affects the reaction [Fenofibrate results in decreased expression of DNAJB4 mRNA]
CTD PMID:21318169 NCBI chr 1:77,979,175...78,017,964
Ensembl chr 1:77,979,175...78,017,964
JBrowse link
G DNAJB6 DnaJ heat shock protein family (Hsp40) member B6 increases expression
multiple interactions
ISO Fenofibrate results in increased expression of DNAJB6 mRNA
PPARA protein affects the reaction [Fenofibrate results in increased expression of DNAJB6 mRNA]
CTD PMID:21318169 NCBI chr 7:157,337,004...157,417,439
Ensembl chr 7:157,335,381...157,417,439
JBrowse link
G DNAJB9 DnaJ heat shock protein family (Hsp40) member B9 decreases expression ISO Fenofibrate results in decreased expression of DNAJB9 mRNA CTD PMID:25596134 NCBI chr 7:108,569,874...108,574,850
Ensembl chr 7:108,569,867...108,574,850
JBrowse link
G DNAJC14 DnaJ heat shock protein family (Hsp40) member C14 increases expression
multiple interactions
ISO Fenofibrate results in increased expression of DNAJC14 mRNA
[PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of DNAJC14 mRNA
CTD PMID:21318169 NCBI chr12:55,820,985...55,830,775
Ensembl chr12:55,820,960...55,830,824
JBrowse link
G DNAJC19 DnaJ heat shock protein family (Hsp40) member C19 increases expression
multiple interactions
ISO Fenofibrate results in increased expression of DNAJC19 mRNA
[PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of DNAJC19 mRNA
CTD PMID:21318169 NCBI chr 3:180,983,709...180,989,838
Ensembl chr 3:180,983,697...180,989,774
JBrowse link
G DNAJC2 DnaJ heat shock protein family (Hsp40) member C2 multiple interactions
increases expression
ISO [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of DNAJC2 mRNA
Fenofibrate results in increased expression of DNAJC2 mRNA
CTD PMID:21318169 NCBI chr 7:103,312,289...103,344,767
Ensembl chr 7:103,312,289...103,344,830
JBrowse link
G DNAJC27 DnaJ heat shock protein family (Hsp40) member C27 decreases expression
multiple interactions
ISO Fenofibrate results in decreased expression of RBJ mRNA
PPARA protein affects the reaction [Fenofibrate results in decreased expression of RBJ mRNA]
CTD PMID:21318169 NCBI chr 2:24,943,636...24,972,094
Ensembl chr 2:24,943,636...24,972,094
JBrowse link
G DNAJC3 DnaJ heat shock protein family (Hsp40) member C3 increases expression
multiple interactions
ISO Fenofibrate results in increased expression of DNAJC3 mRNA
PPARA protein affects the reaction [Fenofibrate results in increased expression of DNAJC3 mRNA]
CTD PMID:21318169 NCBI chr13:95,677,139...95,794,988
Ensembl chr13:95,677,139...95,794,988
JBrowse link
G DNAJC5 DnaJ heat shock protein family (Hsp40) member C5 increases expression
multiple interactions
ISO Fenofibrate results in increased expression of DNAJC5 mRNA
PPARA protein affects the reaction [Fenofibrate results in increased expression of DNAJC5 mRNA]
CTD PMID:21318169 NCBI chr20:63,895,126...63,936,011
Ensembl chr20:63,895,126...63,936,031
JBrowse link
G DNAJC5B DnaJ heat shock protein family (Hsp40) member C5 beta increases expression ISO Fenofibrate results in increased expression of DNAJC5B mRNA CTD PMID:25596134 NCBI chr 8:66,014,978...66,101,245
Ensembl chr 8:66,021,553...66,101,245
JBrowse link
G DNM1L dynamin 1 like multiple interactions EXP Fenofibrate inhibits the reaction [[Fructose co-treated with Palmitic Acid] results in increased expression of DNM1L protein] CTD PMID:32730863 NCBI chr12:32,679,301...32,745,650
Ensembl chr12:32,679,200...32,745,650
JBrowse link
G DNMBP dynamin binding protein decreases expression ISO Fenofibrate results in decreased expression of DNMBP mRNA CTD PMID:25596134 NCBI chr10:99,875,571...100,009,947
Ensembl chr10:99,875,577...100,009,947
JBrowse link
G DUSP5 dual specificity phosphatase 5 increases expression EXP Fenofibrate results in increased expression of DUSP5 mRNA CTD PMID:25596134 NCBI chr10:110,497,907...110,511,533
Ensembl chr10:110,497,907...110,511,533
JBrowse link
G ECH1 enoyl-CoA hydratase 1 affects expression
increases expression
ISO Fenofibrate affects the expression of ECH1 mRNA
Fenofibrate results in increased expression of ECH1 mRNA; Fenofibrate results in increased expression of ECH1 protein
CTD PMID:11798191 PMID:17118139 PMID:20118634 PMID:20801182 PMID:27665778 More... NCBI chr19:38,815,422...38,831,794
Ensembl chr19:38,815,422...38,831,841
JBrowse link
G ECHS1 enoyl-CoA hydratase, short chain 1 increases expression EXP Fenofibrate results in increased expression of ECHS1 mRNA CTD PMID:24752549 NCBI chr10:133,362,485...133,373,354
Ensembl chr10:133,362,485...133,373,354
JBrowse link
G ECI1 enoyl-CoA delta isomerase 1 increases expression
affects expression
ISO Fenofibrate results in increased expression of ECI1 mRNA
Fenofibrate affects the expression of ECI1 mRNA
CTD PMID:11798191 PMID:20801182 PMID:27665778 PMID:32741897 NCBI chr16:2,239,402...2,251,587
Ensembl chr16:2,239,402...2,252,300
JBrowse link
G ECI2 enoyl-CoA delta isomerase 2 increases expression ISO Fenofibrate results in increased expression of ECI2 mRNA CTD PMID:16707586 NCBI chr 6:4,115,706...4,135,575
Ensembl chr 6:4,115,693...4,135,597
JBrowse link
G EDN1 endothelin 1 multiple interactions ISO EDN1 protein promotes the reaction [Fenofibrate promotes the reaction [NFATC4 protein binds to PPARA protein]]; Fenofibrate inhibits the reaction [EDN1 protein promotes the reaction [NFATC4 protein binds to GATA4 protein]]; Fenofibrate inhibits the reaction [EDN1 protein promotes the reaction [NFATC4 protein binds to NPPB promoter]]; Fenofibrate inhibits the reaction [EDN1 protein results in increased expression of NPPB mRNA]; PPARA mutant form inhibits the reaction [Fenofibrate inhibits the reaction [EDN1 protein promotes the reaction [NFATC4 protein binds to GATA4 protein]]]; PPARA mutant form inhibits the reaction [Fenofibrate inhibits the reaction [EDN1 protein results in increased expression of NPPB mRNA]]
Fenofibrate affects the reaction [[AHR protein affects the susceptibility to AGT protein] which affects the expression of EDN1 mRNA]
CTD PMID:22198280 PMID:31016362 NCBI chr 6:12,230,516...12,297,194
Ensembl chr 6:12,290,361...12,297,194
JBrowse link
G EGFR epidermal growth factor receptor decreases expression ISO Fenofibrate results in decreased expression of EGFR mRNA CTD PMID:11798191 NCBI chr 7:55,019,017...55,211,628
Ensembl chr 7:55,019,017...55,211,628
JBrowse link
G EHHADH enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase increases expression
affects expression
ISO Fenofibrate results in increased expression of EHHADH mRNA
Fenofibrate affects the expression of EHHADH mRNA
CTD PMID:11798191 PMID:17118139 PMID:20801182 PMID:27665778 PMID:32741897 NCBI chr 3:185,190,624...185,254,049
Ensembl chr 3:185,190,624...185,281,990
JBrowse link
G EIF1 eukaryotic translation initiation factor 1 decreases expression
increases expression
ISO
EXP
Fenofibrate results in decreased expression of EIF1 mRNA
Fenofibrate results in increased expression of EIF1 mRNA
CTD PMID:25596134 NCBI chr17:41,688,885...41,692,668
Ensembl chr17:41,688,885...41,692,668
JBrowse link
G EIF2AK3 eukaryotic translation initiation factor 2 alpha kinase 3 multiple interactions ISO Fenofibrate inhibits the reaction [Dietary Fats results in increased phosphorylation of EIF2AK3 protein] CTD PMID:38216941 NCBI chr 2:88,556,741...88,628,145
Ensembl chr 2:88,556,741...88,691,518
JBrowse link
G EIF2S2 eukaryotic translation initiation factor 2 subunit beta affects expression ISO Fenofibrate affects the expression of EIF2S2 mRNA CTD PMID:25596134 NCBI chr20:34,088,309...34,112,243
Ensembl chr20:34,088,309...34,112,243
JBrowse link
G EIF3C eukaryotic translation initiation factor 3 subunit C increases expression ISO Fenofibrate results in increased expression of EIF3C mRNA CTD PMID:25596134 NCBI chr16:28,688,558...28,735,730
Ensembl chr16:28,688,558...28,735,727
JBrowse link
G ELK4 ETS transcription factor ELK4 increases expression EXP Fenofibrate results in increased expression of ELK4 mRNA CTD PMID:25596134 NCBI chr 1:205,607,943...205,632,011
Ensembl chr 1:205,597,556...205,632,011
JBrowse link
G ELOVL6 ELOVL fatty acid elongase 6 multiple interactions
increases expression
EXP
ISO
[Oleic Acid co-treated with Fenofibrate] affects the expression of ELOVL6 mRNA
Fenofibrate results in increased expression of ELOVL6 mRNA
NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ELOVL6 mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ELOVL6 mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ELOVL6 mRNA]
CTD PMID:23063693 PMID:24534255 PMID:27665778 NCBI chr 4:110,045,846...110,199,202
Ensembl chr 4:110,045,846...110,199,199
JBrowse link
G ENC1 ectodermal-neural cortex 1 increases expression
multiple interactions
ISO Fenofibrate results in increased expression of ENC1 mRNA
PPARA protein affects the reaction [Fenofibrate results in increased expression of ENC1 mRNA]
CTD PMID:21318169 NCBI chr 5:74,627,409...74,640,728
Ensembl chr 5:74,627,406...74,641,424
JBrowse link
G ENO1 enolase 1 increases expression EXP Fenofibrate results in increased expression of ENO1 mRNA CTD PMID:25596134 NCBI chr 1:8,861,000...8,878,686
Ensembl chr 1:8,861,000...8,879,190
JBrowse link
G ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 decreases expression EXP Fenofibrate results in decreased expression of ENPP2 mRNA CTD PMID:25572481 NCBI chr 8:119,557,086...119,673,390
Ensembl chr 8:119,557,086...119,673,453
JBrowse link
G ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7 decreases expression EXP Fenofibrate results in decreased expression of ENTPD7 mRNA CTD PMID:25596134 NCBI chr10:99,659,509...99,711,241
Ensembl chr10:99,659,509...99,711,241
JBrowse link
G EP400 E1A binding protein p400 decreases expression ISO Fenofibrate results in decreased expression of EP400 mRNA CTD PMID:25596134 NCBI chr12:131,949,942...132,080,460
Ensembl chr12:131,949,942...132,080,460
JBrowse link
G EPHX2 epoxide hydrolase 2 affects expression
increases expression
ISO
EXP
Fenofibrate affects the expression of EPHX2 mRNA
Fenofibrate results in increased expression of EPHX2 mRNA
Fenofibrate affects the expression of EPHX2 protein
CTD PMID:20801182 PMID:29960002 PMID:32741897 NCBI chr 8:27,491,143...27,548,626
Ensembl chr 8:27,490,781...27,545,564
JBrowse link
G EPRS1 glutamyl-prolyl-tRNA synthetase 1 increases expression EXP
ISO
Fenofibrate results in increased expression of EPRS1 mRNA CTD PMID:25596134 NCBI chr 1:219,968,600...220,046,505
Ensembl chr 1:219,968,600...220,046,530
JBrowse link
G ERO1A endoplasmic reticulum oxidoreductase 1 alpha increases expression ISO Fenofibrate results in increased expression of ERO1A mRNA CTD PMID:25596134 NCBI chr14:52,639,915...52,695,558
Ensembl chr14:52,639,915...52,695,900
JBrowse link
G ESR1 estrogen receptor 1 multiple interactions EXP [ESR1 protein results in increased susceptibility to Estradiol] inhibits the reaction [Fenofibrate results in decreased expression of CASP3 protein]; ESR1 protein inhibits the reaction [Estradiol inhibits the reaction [Fenofibrate inhibits the reaction [ESR1 protein binds to PPARA protein]]]; ESR1 protein inhibits the reaction [Fenofibrate inhibits the reaction [ESR1 protein binds to PPARA protein]]; ESR1 protein inhibits the reaction [Fenofibrate results in decreased expression of CDKN1B protein]; ESR1 protein inhibits the reaction [Fenofibrate results in increased expression of CCND1 protein]; ESR1 protein inhibits the reaction [Fenofibrate results in increased expression of PCNA protein]; Estradiol inhibits the reaction [ESR1 protein inhibits the reaction [Fenofibrate inhibits the reaction [ESR1 protein binds to PPARA protein]]]; Estradiol inhibits the reaction [Fenofibrate inhibits the reaction [ESR1 protein binds to PPARA protein]]; Fenofibrate inhibits the reaction [ESR1 protein binds to PPARA protein] CTD PMID:29134746 NCBI chr 6:151,656,672...152,129,619
Ensembl chr 6:151,656,691...152,129,619
JBrowse link
G ETFA electron transfer flavoprotein subunit alpha increases expression EXP Fenofibrate results in increased expression of ETFA mRNA CTD PMID:25572481 NCBI chr15:76,215,353...76,311,469
Ensembl chr15:76,188,555...76,311,730
JBrowse link
G ETFDH electron transfer flavoprotein dehydrogenase decreases expression
increases expression
ISO
EXP
Fenofibrate results in decreased expression of ETFDH protein
Fenofibrate results in increased expression of ETFDH mRNA
CTD PMID:20118634 PMID:25572481 NCBI chr 4:158,672,296...158,709,623
Ensembl chr 4:158,671,968...158,710,742
JBrowse link
G ETNK2 ethanolamine kinase 2 decreases expression EXP Fenofibrate results in decreased expression of ETNK2 mRNA CTD PMID:25572481 NCBI chr 1:204,131,062...204,152,044
Ensembl chr 1:204,131,062...204,152,044
JBrowse link
G F2 coagulation factor II, thrombin multiple interactions EXP Fenofibrate promotes the reaction [Warfarin results in decreased expression of F2 protein] CTD PMID:9681093 NCBI chr11:46,719,213...46,739,506
Ensembl chr11:46,719,196...46,739,506
JBrowse link
G F7 coagulation factor VII multiple interactions EXP Fenofibrate promotes the reaction [Warfarin results in decreased expression of F7 protein] CTD PMID:9681093 NCBI chr13:113,105,788...113,120,685
Ensembl chr13:113,105,788...113,120,685
JBrowse link
G FABP1 fatty acid binding protein 1 increases expression
multiple interactions
ISO
EXP
Fenofibrate results in increased expression of FABP1 mRNA
Fenofibrate inhibits the reaction [Pyrazinamide results in decreased expression of FABP1 mRNA]
CTD PMID:17118139 PMID:24752549 PMID:27071702 PMID:32741897 NCBI chr 2:88,122,982...88,128,062
Ensembl chr 2:88,122,982...88,128,062
JBrowse link
G FABP2 fatty acid binding protein 2 increases expression ISO Fenofibrate results in increased expression of FABP2 mRNA CTD PMID:17118139 NCBI chr 4:119,317,250...119,322,138
Ensembl chr 4:119,317,250...119,322,138
JBrowse link
G FABP3 fatty acid binding protein 3 increases expression ISO Fenofibrate results in increased expression of FABP3 mRNA CTD PMID:25596134 NCBI chr 1:31,359,588...31,373,076
Ensembl chr 1:31,365,253...31,376,850
JBrowse link
G FABP4 fatty acid binding protein 4 increases expression ISO
EXP
Fenofibrate results in increased expression of FABP4 mRNA CTD PMID:11798191 PMID:12759900 PMID:25572481 NCBI chr 8:81,478,419...81,483,233
Ensembl chr 8:81,478,419...81,483,236
JBrowse link
G FADS1 fatty acid desaturase 1 multiple interactions
increases expression
EXP beta-hydroxy simvastatin acid promotes the reaction [Fenofibrate results in increased expression of FADS1 mRNA]; Fenofibrate promotes the reaction [beta-hydroxy simvastatin acid results in increased expression of FADS1 mRNA] CTD PMID:17655842 NCBI chr11:61,799,627...61,817,003
Ensembl chr11:61,799,627...61,829,318
JBrowse link
G FAH fumarylacetoacetate hydrolase increases expression EXP Fenofibrate results in increased expression of FAH mRNA CTD PMID:25572481 NCBI chr15:80,152,789...80,186,949
Ensembl chr15:80,152,490...80,186,946
JBrowse link
G FAM210A family with sequence similarity 210 member A affects expression ISO Fenofibrate affects the expression of FAM210A mRNA CTD PMID:25596134 NCBI chr18:13,663,347...13,726,558
Ensembl chr18:13,663,347...13,726,663
JBrowse link
G FAM222A family with sequence similarity 222 member A increases expression EXP Fenofibrate results in increased expression of FAM222A mRNA CTD PMID:25572481 NCBI chr12:109,713,825...109,770,495
Ensembl chr12:109,713,825...109,770,495
JBrowse link
G FAM241A family with sequence similarity 241 member A increases expression EXP Fenofibrate results in increased expression of FAM241A mRNA CTD PMID:25572481 NCBI chr 4:112,145,454...112,195,256
Ensembl chr 4:112,145,454...112,195,256
JBrowse link
G FAM89A family with sequence similarity 89 member A increases expression EXP Fenofibrate results in increased expression of FAM89A mRNA CTD PMID:25596134 NCBI chr 1:231,018,958...231,040,254
Ensembl chr 1:231,018,958...231,040,254
JBrowse link
G FAS Fas cell surface death receptor multiple interactions
decreases expression
ISO
EXP
Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of FAS mRNA]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of FAS mRNA]]
fenofibrate co-treated with fructose diet increases expression of Fas mRNA in liver
Fenofibrate results in decreased expression of FAS mRNA
CTD
RGD
PMID:19593819 PMID:25596134 PMID:11934685 RGD:628329 NCBI chr10:88,964,050...89,017,059
Ensembl chr10:88,953,813...89,029,605
JBrowse link
G FASN fatty acid synthase multiple interactions
increases expression
EXP
ISO
[Oleic Acid co-treated with Fenofibrate] affects the expression of FASN mRNA; Fenofibrate inhibits the reaction [[Fructose co-treated with Palmitic Acid] results in increased expression of FASN protein]
[Fenofibrate co-treated with resveratrol] inhibits the reaction [Fructose results in increased expression of FASN mRNA]; Fenofibrate inhibits the reaction [Fructose results in increased expression of FASN mRNA]
Fenofibrate results in increased expression of FASN mRNA
NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of FASN mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of FASN mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of FASN mRNA]
CTD PMID:17118139 PMID:23063693 PMID:24534255 PMID:26973390 PMID:32730863 NCBI chr17:82,078,338...82,098,236
Ensembl chr17:82,078,338...82,098,294
JBrowse link
G FBP2 fructose-bisphosphatase 2 increases expression ISO Fenofibrate results in increased expression of FBP2 mRNA CTD PMID:32741897 NCBI chr 9:94,558,720...94,593,824
Ensembl chr 9:94,558,720...94,593,824
JBrowse link
G FBXO21 F-box protein 21 increases expression ISO Fenofibrate results in increased expression of FBXO21 mRNA CTD PMID:21318169 NCBI chr12:117,141,991...117,190,470
Ensembl chr12:117,141,991...117,190,470
JBrowse link
G FBXO22 F-box protein 22 decreases expression ISO Fenofibrate results in decreased expression of FBXO22 mRNA CTD PMID:25596134 NCBI chr15:75,903,878...75,942,511
Ensembl chr15:75,903,876...75,942,511
JBrowse link
G FBXO3 F-box protein 3 increases expression
multiple interactions
ISO Fenofibrate results in increased expression of FBXO3 mRNA
PPARA protein affects the reaction [Fenofibrate results in increased expression of FBXO3 mRNA]
CTD PMID:21318169 NCBI chr11:33,740,944...33,774,520
Ensembl chr11:33,740,939...33,774,543
JBrowse link
G FBXO30 F-box protein 30 increases expression
multiple interactions
ISO Fenofibrate results in increased expression of FBXO30 mRNA
PPARA protein affects the reaction [Fenofibrate results in increased expression of FBXO30 mRNA]
CTD PMID:21318169 PMID:25596134 NCBI chr 6:145,793,502...145,814,795
Ensembl chr 6:145,793,502...145,814,795
JBrowse link
G FBXO32 F-box protein 32 multiple interactions
increases expression
ISO Lovastatin promotes the reaction [Fenofibrate results in increased expression of FBXO32 protein]; PPARA protein affects the reaction [Fenofibrate results in increased expression of FBXO32 mRNA]
Fenofibrate results in increased expression of FBXO32 mRNA; Fenofibrate results in increased expression of FBXO32 protein
CTD PMID:33408297 NCBI chr 8:123,497,889...123,541,206
Ensembl chr 8:123,497,889...123,541,206
JBrowse link
G FBXO36 F-box protein 36 decreases expression ISO Fenofibrate results in decreased expression of FBXO36 mRNA CTD PMID:21318169 NCBI chr 2:229,922,503...230,013,119
Ensembl chr 2:229,922,302...230,013,119
JBrowse link
G FBXO9 F-box protein 9 increases expression ISO Fenofibrate results in increased expression of FBXO9 mRNA CTD PMID:21318169 NCBI chr 6:53,064,998...53,100,873
Ensembl chr 6:53,051,991...53,100,873
JBrowse link
G FDFT1 farnesyl-diphosphate farnesyltransferase 1 increases expression
multiple interactions
ISO Fenofibrate results in increased expression of FDFT1 mRNA
NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of FDFT1 mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of FDFT1 mRNA]
CTD PMID:23063693 NCBI chr 8:11,795,582...11,839,298
Ensembl chr 8:11,795,573...11,839,395
JBrowse link
G FGA fibrinogen alpha chain multiple interactions
decreases expression
ISO PPARA promotes the reaction [Fenofibrate results in decreased expression of FGA mRNA] CTD PMID:10216095 NCBI chr 4:154,583,126...154,590,742
Ensembl chr 4:154,583,126...154,590,742
JBrowse link
G FGB fibrinogen beta chain decreases expression ISO Fenofibrate results in decreased expression of FGB mRNA CTD PMID:10216095 NCBI chr 4:154,562,980...154,572,807
Ensembl chr 4:154,563,011...154,572,807
JBrowse link
G FGF21 fibroblast growth factor 21 increases expression EXP Fenofibrate results in increased expression of FGF21 mRNA; Fenofibrate results in increased expression of FGF21 protein CTD PMID:22338096 NCBI chr19:48,755,524...48,758,330
Ensembl chr19:48,755,524...48,758,333
JBrowse link
G FGG fibrinogen gamma chain decreases expression ISO Fenofibrate results in decreased expression of FGG mRNA CTD PMID:10216095 NCBI chr 4:154,604,136...154,612,656
Ensembl chr 4:154,604,134...154,612,967
JBrowse link
G FGR FGR proto-oncogene, Src family tyrosine kinase affects expression ISO Fenofibrate affects the expression of FGR mRNA CTD PMID:25596134 NCBI chr 1:27,612,064...27,635,185
Ensembl chr 1:27,612,064...27,635,185
JBrowse link
G FIS1 fission, mitochondrial 1 multiple interactions EXP Fenofibrate inhibits the reaction [[Fructose co-treated with Palmitic Acid] results in increased expression of FIS1 protein] CTD PMID:32730863 NCBI chr 7:101,239,472...101,245,081
Ensembl chr 7:101,239,458...101,252,316
JBrowse link
G FKBP15 FKBP prolyl isomerase family member 15 increases expression
multiple interactions
ISO Fenofibrate results in increased expression of FKBP15 mRNA
[PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of FKBP15 mRNA
CTD PMID:21318169 NCBI chr 9:113,161,006...113,221,277
Ensembl chr 9:113,161,006...113,221,458
JBrowse link
G FKBP8 FKBP prolyl isomerase 8 increases expression ISO Fenofibrate results in increased expression of FKBP8 mRNA CTD PMID:21318169 NCBI chr19:18,531,763...18,543,573
Ensembl chr19:18,531,751...18,544,077
JBrowse link
G FMO1 flavin containing dimethylaniline monoxygenase 1 multiple interactions ISO [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of FMO1 mRNA CTD PMID:18253720 NCBI chr 1:171,248,494...171,285,978
Ensembl chr 1:171,248,471...171,285,978
JBrowse link
G FMO5 flavin containing dimethylaniline monoxygenase 5 multiple interactions
decreases expression
ISO
EXP
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of FMO5 mRNA
Fenofibrate results in decreased expression of FMO5 mRNA
CTD PMID:18253720 PMID:25572481 NCBI chr 1:147,184,305...147,227,284
Ensembl chr 1:147,175,351...147,243,050
JBrowse link
G FN1 fibronectin 1 affects expression
multiple interactions
ISO Fenofibrate affects the expression of FN1 mRNA
Fenofibrate inhibits the reaction [zoledronic acid results in increased expression of FN1 protein]
CTD PMID:20801182 PMID:28871336 NCBI chr 2:215,360,865...215,436,068
Ensembl chr 2:215,360,440...215,436,073
JBrowse link
G FOXO1 forkhead box O1 increases expression
multiple interactions
ISO Fenofibrate results in increased expression of FOXO1 mRNA; Fenofibrate results in increased expression of FOXO1 protein
Lovastatin promotes the reaction [Fenofibrate results in increased expression of FOXO1 protein]; PPARA protein affects the reaction [Fenofibrate results in increased expression of FOXO1 mRNA]
CTD PMID:33408297 NCBI chr13:40,555,667...40,666,641
Ensembl chr13:40,555,667...40,666,641
JBrowse link
G FOXQ1 forkhead box Q1 decreases expression ISO Fenofibrate results in decreased expression of FOXQ1 mRNA CTD PMID:11798191 NCBI chr 6:1,312,098...1,314,758
Ensembl chr 6:1,312,098...1,314,758
JBrowse link
G G6PC1 glucose-6-phosphatase catalytic subunit 1 decreases expression EXP Fenofibrate results in decreased expression of G6PC1 mRNA CTD PMID:25572481 NCBI chr17:42,900,799...42,914,438
Ensembl chr17:42,900,797...42,914,438
JBrowse link
G GADD45A growth arrest and DNA damage inducible alpha multiple interactions
increases expression
ISO [Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of GADD45A mRNA
Fenofibrate results in increased expression of GADD45A mRNA
CTD PMID:17264098 PMID:18253720 PMID:18775883 PMID:25596134 NCBI chr 1:67,685,201...67,688,334
Ensembl chr 1:67,685,201...67,688,334
JBrowse link
G GADD45B growth arrest and DNA damage inducible beta multiple interactions ISO [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of GADD45B mRNA CTD PMID:18253720 NCBI chr19:2,476,127...2,478,257
Ensembl chr19:2,476,122...2,478,805
JBrowse link
G GALT galactose-1-phosphate uridylyltransferase increases expression EXP Fenofibrate results in increased expression of GALT mRNA CTD PMID:25572481 NCBI chr 9:34,646,675...34,651,035
Ensembl chr 9:34,638,133...34,651,035
JBrowse link
G GARS1 glycyl-tRNA synthetase 1 increases expression EXP Fenofibrate results in increased expression of GARS1 mRNA CTD PMID:25596134 NCBI chr 7:30,594,735...30,634,033
Ensembl chr 7:30,580,533...30,634,033
JBrowse link
G GATA4 GATA binding protein 4 multiple interactions ISO Fenofibrate inhibits the reaction [EDN1 protein promotes the reaction [NFATC4 protein binds to GATA4 protein]]; PPARA mutant form inhibits the reaction [Fenofibrate inhibits the reaction [EDN1 protein promotes the reaction [NFATC4 protein binds to GATA4 protein]]] CTD PMID:22198280 NCBI chr 8:11,676,935...11,760,002
Ensembl chr 8:11,676,959...11,760,002
JBrowse link
G GBE1 1,4-alpha-glucan branching enzyme 1 decreases expression
increases expression
ISO
EXP
Fenofibrate results in decreased expression of GBE1 mRNA
Fenofibrate results in increased expression of GBE1 mRNA
CTD PMID:25596134 NCBI chr 3:81,489,703...81,761,645
Ensembl chr 3:81,489,703...81,761,645
JBrowse link
G GCAT glycine C-acetyltransferase decreases expression EXP Fenofibrate results in decreased expression of GCAT mRNA CTD PMID:25572481 NCBI chr22:37,807,934...37,817,183
Ensembl chr22:37,807,905...37,817,176
JBrowse link
G GCLC glutamate-cysteine ligase catalytic subunit decreases expression
multiple interactions
ISO Fenofibrate results in decreased expression of GCLC mRNA
Fenofibrate inhibits the reaction [tyloxapol results in decreased expression of GCLC protein]
CTD PMID:25596134 PMID:36905866 NCBI chr 6:53,497,341...53,545,101
Ensembl chr 6:53,497,341...53,616,970
JBrowse link
G GCLM glutamate-cysteine ligase modifier subunit increases expression EXP Fenofibrate results in increased expression of GCLM mRNA CTD PMID:25596134 NCBI chr 1:93,885,199...93,909,430
Ensembl chr 1:93,885,199...93,909,456
JBrowse link
G GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type increases expression EXP Fenofibrate results in increased expression of GCNT3 mRNA CTD PMID:25596134 NCBI chr15:59,611,783...59,622,723
Ensembl chr15:59,594,875...59,640,239
JBrowse link
G GDE1 glycerophosphodiester phosphodiesterase 1 affects expression ISO Fenofibrate affects the expression of GDE1 mRNA CTD PMID:20801182 NCBI chr16:19,501,693...19,522,098
Ensembl chr16:19,501,693...19,522,123
JBrowse link
G GDF15 growth differentiation factor 15 increases expression EXP
ISO
Fenofibrate results in increased expression of GDF15 mRNA CTD PMID:25596134 NCBI chr19:18,386,158...18,389,176
Ensembl chr19:18,374,731...18,389,176
JBrowse link
G GK glycerol kinase increases expression EXP
ISO
Fenofibrate results in increased expression of GK mRNA CTD PMID:25572481 PMID:32741897 NCBI chr  X:30,653,423...30,731,462
Ensembl chr  X:30,653,359...30,731,462
JBrowse link
G GMNN geminin DNA replication inhibitor increases expression ISO Fenofibrate results in increased expression of GMNN mRNA CTD PMID:32741897 NCBI chr 6:24,774,937...24,786,099
Ensembl chr 6:24,774,931...24,786,099
JBrowse link
G GNMT glycine N-methyltransferase decreases expression EXP Fenofibrate results in decreased expression of GNMT mRNA CTD PMID:25572481 NCBI chr 6:42,960,754...42,963,880
Ensembl chr 6:42,960,754...42,963,880
JBrowse link
G GOT1 glutamic-oxaloacetic transaminase 1 increases expression
multiple interactions
ISO Fenofibrate results in increased expression of GOT1 mRNA
Fenofibrate inhibits the reaction [Dietary Fats results in increased expression of GOT1 protein]
CTD PMID:25596134 PMID:38216941 NCBI chr10:99,396,870...99,430,624
Ensembl chr10:99,396,870...99,430,624
JBrowse link
G GOT2 glutamic-oxaloacetic transaminase 2 increases expression ISO Fenofibrate results in increased expression of GOT2 mRNA CTD PMID:19652460 NCBI chr16:58,707,131...58,734,316
Ensembl chr16:58,707,131...58,734,342
JBrowse link
G GPAM glycerol-3-phosphate acyltransferase, mitochondrial increases expression ISO Fenofibrate results in increased expression of GPAM mRNA CTD PMID:16707586 NCBI chr10:112,149,865...112,227,677
Ensembl chr10:112,149,865...112,215,377
JBrowse link
G GPAT3 glycerol-3-phosphate acyltransferase 3 increases expression EXP Fenofibrate results in increased expression of GPAT3 mRNA CTD PMID:25596134 NCBI chr 4:83,535,587...83,605,875
Ensembl chr 4:83,535,914...83,605,875
JBrowse link
G GPHN gephyrin increases expression ISO
EXP
Fenofibrate results in increased expression of GPHN mRNA CTD PMID:25596134 NCBI chr14:66,508,147...67,735,355
Ensembl chr14:66,507,407...67,181,803
JBrowse link
G GPT glutamic--pyruvic transaminase multiple interactions ISO Fenofibrate inhibits the reaction [Dietary Fats results in increased expression of GPT protein]; Fenofibrate inhibits the reaction [Pyrazinamide results in increased expression of GPT protein]
Fenofibrate inhibits the reaction [tyloxapol results in increased expression of GPT protein]
CTD PMID:27071702 PMID:36905866 PMID:38216941 NCBI chr 8:144,503,068...144,507,172
Ensembl chr 8:144,502,973...144,507,174
JBrowse link
G GPX1 glutathione peroxidase 1 multiple interactions ISO Fenofibrate inhibits the reaction [triptolide results in increased expression of GPX1 mRNA] CTD PMID:31241159 NCBI chr 3:49,357,176...49,358,353
Ensembl chr 3:49,357,174...49,358,605
JBrowse link
G GPX2 glutathione peroxidase 2 multiple interactions
increases expression
ISO [Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of GPX2 mRNA
Fenofibrate inhibits the reaction [triptolide results in increased expression of GPX2 mRNA]
Fenofibrate results in increased expression of GPX2 mRNA
CTD PMID:17264098 PMID:18253720 PMID:18775883 PMID:31241159 NCBI chr14:64,939,158...64,942,745
Ensembl chr14:64,939,152...64,942,746
JBrowse link
G GPX3 glutathione peroxidase 3 multiple interactions ISO Fenofibrate inhibits the reaction [triptolide results in increased expression of GPX3 mRNA] CTD PMID:31241159 NCBI chr 5:151,020,591...151,028,988
Ensembl chr 5:151,020,591...151,028,988
JBrowse link
G GPX4 glutathione peroxidase 4 multiple interactions ISO Fenofibrate inhibits the reaction [triptolide results in increased expression of GPX4 mRNA] CTD PMID:31241159 NCBI chr19:1,103,994...1,106,779
Ensembl chr19:1,103,982...1,106,791
JBrowse link
G GRM3 glutamate metabotropic receptor 3 increases expression EXP Fenofibrate results in increased expression of GRM3 mRNA CTD PMID:25572481 NCBI chr 7:86,643,909...86,864,879
Ensembl chr 7:86,643,909...86,864,879
JBrowse link
G GRPEL2 GrpE like 2, mitochondrial increases expression
multiple interactions
ISO Fenofibrate results in increased expression of GRPEL2 mRNA
PPARA protein affects the reaction [Fenofibrate results in increased expression of GRPEL2 mRNA]
CTD PMID:21318169 NCBI chr 5:149,345,499...149,354,583
Ensembl chr 5:149,345,430...149,354,583
JBrowse link
G GSR glutathione-disulfide reductase increases expression ISO Fenofibrate results in increased expression of GSR mRNA CTD PMID:25596134 NCBI chr 8:30,678,066...30,727,846
Ensembl chr 8:30,678,066...30,727,846
JBrowse link
G GSTA2 glutathione S-transferase alpha 2 decreases expression
multiple interactions
ISO Fenofibrate results in decreased expression of GSTA2 mRNA
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of GSTA2 mRNA
CTD PMID:18253720 PMID:18775883 NCBI chr 6:52,750,087...52,763,475
Ensembl chr 6:52,750,087...52,763,475
JBrowse link
G GSTA5 glutathione S-transferase alpha 5 increases expression
multiple interactions
ISO Fenofibrate results in increased expression of GSTA5 mRNA
[Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of GSTA5 mRNA
CTD PMID:17264098 PMID:18253720 PMID:18775883 NCBI chr 6:52,831,692...52,846,245
Ensembl chr 6:52,831,655...52,840,843
JBrowse link
G GSTM2 glutathione S-transferase mu 2 multiple interactions
decreases expression
ISO [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of GSTM2 mRNA
Fenofibrate results in decreased expression of GSTM2 mRNA
CTD PMID:18253720 PMID:18775883 NCBI chr 1:109,668,057...109,683,997
Ensembl chr 1:109,668,022...109,709,551
JBrowse link
G GSTM3 glutathione S-transferase mu 3 multiple interactions
decreases expression
ISO [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of GSTM3 mRNA
Fenofibrate results in decreased expression of GSTM3 mRNA
CTD PMID:18253720 PMID:18775883 NCBI chr 1:109,733,937...109,741,038
Ensembl chr 1:109,733,932...109,741,038
JBrowse link
G GSTP1 glutathione S-transferase pi 1 multiple interactions EXP Fenofibrate inhibits the reaction [GSTP1 protein results in increased metabolism of 1-chloro-2,4-dinitrobenzene-glutathione conjugate] CTD PMID:23769903 NCBI chr11:67,583,812...67,586,653
Ensembl chr11:67,583,742...67,586,656
JBrowse link
G GTSE1 G2 and S-phase expressed 1 increases expression ISO Fenofibrate results in increased expression of GTSE1 mRNA CTD PMID:32741897 NCBI chr22:46,296,870...46,330,810
Ensembl chr22:46,296,870...46,330,810
JBrowse link
G H1-2 H1.2 linker histone, cluster member decreases expression EXP Fenofibrate results in decreased expression of H1-2 mRNA CTD PMID:25596134 NCBI chr 6:26,055,740...26,056,470
Ensembl chr 6:26,054,760...26,056,470
JBrowse link
G HADH hydroxyacyl-CoA dehydrogenase increases expression EXP Fenofibrate results in increased expression of HADH mRNA CTD PMID:24752549 NCBI chr 4:107,989,889...108,035,171
Ensembl chr 4:107,989,714...108,035,241
JBrowse link
G HADHA hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha increases expression
decreases expression
ISO
EXP
Fenofibrate results in increased expression of HADHA mRNA
Fenofibrate results in decreased expression of HADHA protein
CTD PMID:16707586 PMID:17118139 PMID:20118634 PMID:25572481 NCBI chr 2:26,190,635...26,244,632
Ensembl chr 2:26,190,635...26,244,672
JBrowse link
G HADHB hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta increases expression
decreases expression
affects expression
ISO
EXP
Fenofibrate results in increased expression of HADHB mRNA
Fenofibrate results in decreased expression of HADHB protein
Fenofibrate affects the expression of HADHB mRNA
CTD PMID:17118139 PMID:20118634 PMID:20801182 PMID:24752549 PMID:25572481 NCBI chr 2:26,244,939...26,290,465
Ensembl chr 2:26,243,170...26,290,465
JBrowse link
G HAL histidine ammonia-lyase decreases expression ISO Fenofibrate results in decreased expression of HAL mRNA CTD PMID:32741898 NCBI chr12:95,972,662...95,996,344
Ensembl chr12:95,972,662...95,996,365
JBrowse link
G HDC histidine decarboxylase increases expression ISO Fenofibrate results in increased expression of HDC mRNA; Fenofibrate results in increased expression of HDC protein CTD PMID:32741897 PMID:32741898 NCBI chr15:50,241,947...50,265,726
Ensembl chr15:50,241,947...50,265,965
JBrowse link
G HDGFL3 HDGF like 3 increases expression ISO Fenofibrate results in increased expression of HDGFL3 mRNA CTD PMID:17264098 NCBI chr15:83,112,738...83,207,823
Ensembl chr15:83,112,738...83,207,875
JBrowse link
G HECTD1 HECT domain E3 ubiquitin protein ligase 1 increases expression
multiple interactions
ISO Fenofibrate results in increased expression of HECTD1 mRNA
[PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of HECTD1 mRNA
CTD PMID:21318169 NCBI chr14:31,100,117...31,207,793
Ensembl chr14:31,100,117...31,207,804
JBrowse link
G HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3 increases expression EXP Fenofibrate results in increased expression of HERC3 mRNA CTD PMID:25596134 NCBI chr 4:88,523,843...88,708,539
Ensembl chr 4:88,523,810...88,708,450
Ensembl chr 4:88,523,810...88,708,450
JBrowse link
G HES1 hes family bHLH transcription factor 1 multiple interactions ISO Fenofibrate inhibits the reaction [triptolide results in increased expression of HES1 mRNA] CTD PMID:31241159 NCBI chr 3:194,136,148...194,138,732
Ensembl chr 3:194,136,148...194,138,732
JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha increases expression
multiple interactions
affects activity
ISO
EXP
Fenofibrate results in increased expression of HIF1A mRNA
Fenofibrate inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]; Fenofibrate results in decreased expression of and results in increased degradation of HIF1A protein
Fenofibrate affects the activity of HIF1A protein
CTD PMID:17118139 PMID:25596134 PMID:34520103 NCBI chr14:61,695,513...61,748,258
Ensembl chr14:61,695,513...61,748,259
JBrowse link
G HILPDA hypoxia inducible lipid droplet associated increases expression ISO Fenofibrate results in increased expression of HILPDA mRNA CTD PMID:32741897 NCBI chr 7:128,455,878...128,458,418
Ensembl chr 7:128,455,849...128,458,418
JBrowse link
G HLA-A major histocompatibility complex, class I, A affects response to substance EXP HLA-A gene polymorphism affects the susceptibility to Fenofibrate CTD PMID:28043905 NCBI chr 6:29,942,532...29,945,870
Ensembl chr 6:29,941,260...29,949,572
JBrowse link
G HLA-DRB1 major histocompatibility complex, class II, DR beta 1 decreases expression ISO Fenofibrate results in decreased expression of H2-EB1 mRNA CTD PMID:11798191 NCBI chr 6:32,578,775...32,589,848
Ensembl chr 6:32,577,902...32,589,848
JBrowse link
G HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase increases expression
decreases expression
multiple interactions
ISO Fenofibrate results in increased expression of HMGCR mRNA
Fenofibrate results in decreased expression of HMGCR mRNA
NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of HMGCR mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of HMGCR mRNA]
CTD PMID:16595124 PMID:23063693 NCBI chr 5:75,336,529...75,362,116
Ensembl chr 5:75,336,329...75,364,001
JBrowse link
G HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 increases expression ISO Fenofibrate results in increased expression of HMGCS1 mRNA CTD PMID:11798191 NCBI chr 5:43,287,470...43,313,412
Ensembl chr 5:43,287,470...43,313,512
JBrowse link
G HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 increases expression EXP
ISO
Fenofibrate results in increased expression of HMGCS2 mRNA CTD PMID:25572481 PMID:27665778 PMID:32741897 NCBI chr 1:119,747,996...119,768,932
Ensembl chr 1:119,748,002...119,768,905
JBrowse link
G HMOX1 heme oxygenase 1 increases expression
multiple interactions
ISO
EXP
Fenofibrate results in increased expression of HMOX1 mRNA
dorsomorphin inhibits the reaction [Fenofibrate results in increased expression of HMOX1 protein]
Fenofibrate results in increased expression of HMOX1 mRNA; Fenofibrate results in increased expression of HMOX1 protein
CTD PMID:25596134 PMID:34520103 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214
JBrowse link
G HOGA1 4-hydroxy-2-oxoglutarate aldolase 1 decreases expression EXP Fenofibrate results in decreased expression of HOGA1 mRNA CTD PMID:25572481 NCBI chr10:97,584,389...97,612,802
Ensembl chr10:97,584,323...97,612,802
JBrowse link
G HRAS HRas proto-oncogene, GTPase multiple interactions ISO [Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of HRAS mRNA CTD PMID:18978307 NCBI chr11:532,242...535,576
Ensembl chr11:532,242...537,321
JBrowse link
G HSD11B1 hydroxysteroid 11-beta dehydrogenase 1 increases expression EXP Fenofibrate results in increased expression of HSD11B1 mRNA CTD PMID:25572481 NCBI chr 1:209,686,179...209,734,929
Ensembl chr 1:209,686,178...209,734,949
JBrowse link
G HSD17B4 hydroxysteroid 17-beta dehydrogenase 4 increases expression ISO
EXP
Fenofibrate results in increased expression of HSD17B4 mRNA CTD PMID:17118139 PMID:25572481 NCBI chr 5:119,452,497...119,542,332
Ensembl chr 5:119,452,465...119,637,199
JBrowse link
G HSDL2 hydroxysteroid dehydrogenase like 2 increases expression ISO Fenofibrate results in increased expression of HSDL2 mRNA CTD PMID:32741897 NCBI chr 9:112,380,108...112,472,405
Ensembl chr 9:112,380,080...112,472,405
JBrowse link
G HSF1 heat shock transcription factor 1 multiple interactions ISO [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of HSF1 mRNA CTD PMID:18253720 NCBI chr 8:144,291,604...144,314,720
Ensembl chr 8:144,291,591...144,314,720
JBrowse link
G HSP90AA1 heat shock protein 90 alpha family class A member 1 increases expression
multiple interactions
ISO Fenofibrate results in increased expression of HSP90AA1 mRNA
PPARA protein affects the reaction [Fenofibrate results in increased expression of HSP90AA1 mRNA]
CTD PMID:21318169 NCBI chr14:102,080,742...102,139,749
Ensembl chr14:102,080,742...102,139,699
JBrowse link
G HSP90AB1 heat shock protein 90 alpha family class B member 1 multiple interactions
increases expression
ISO PPARA protein affects the reaction [Fenofibrate results in increased expression of HSP90AB1 mRNA] CTD PMID:21318169 NCBI chr 6:44,246,194...44,253,883
Ensembl chr 6:44,246,166...44,253,888
JBrowse link
G HSP90B1 heat shock protein 90 beta family member 1 increases expression ISO Fenofibrate results in increased expression of HSP90B1 mRNA CTD PMID:21318169 NCBI chr12:103,930,410...103,947,926
Ensembl chr12:103,930,107...103,953,931
JBrowse link
G HSPA13 heat shock protein family A (Hsp70) member 13 decreases expression
multiple interactions
ISO Fenofibrate results in decreased expression of HSPA13 mRNA
PPARA protein affects the reaction [Fenofibrate results in decreased expression of HSPA13 mRNA]
CTD PMID:21318169 NCBI chr21:14,371,115...14,383,146
Ensembl chr21:14,371,115...14,383,484
JBrowse link
G HSPA4L heat shock protein family A (Hsp70) member 4 like increases expression
multiple interactions
ISO Fenofibrate results in increased expression of HSPA4L mRNA
PPARA protein affects the reaction [Fenofibrate results in increased expression of HSPA4L mRNA]
CTD PMID:21318169 NCBI chr 4:127,781,796...127,840,733
Ensembl chr 4:127,781,821...127,840,733
JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 decreases expression
multiple interactions
ISO Fenofibrate results in decreased expression of HSPA5 mRNA
Fenofibrate inhibits the reaction [Dietary Fats results in increased expression of HSPA5 protein]
CTD PMID:25596134 PMID:38216941 NCBI chr 9:125,234,853...125,241,343
Ensembl chr 9:125,234,853...125,241,382
JBrowse link
G HSPA8 heat shock protein family A (Hsp70) member 8 increases expression
multiple interactions
ISO Fenofibrate results in increased expression of HSPA8 mRNA
PPARA protein affects the reaction [Fenofibrate results in increased expression of HSPA8 mRNA]
CTD PMID:21318169 NCBI chr11:123,057,489...123,062,462
Ensembl chr11:123,057,489...123,063,230
JBrowse link
G HSPA9 heat shock protein family A (Hsp70) member 9 increases expression
multiple interactions
ISO Fenofibrate results in increased expression of HSPA9 mRNA
PPARA protein affects the reaction [Fenofibrate results in increased expression of HSPA9 mRNA]
CTD PMID:21318169 NCBI chr 5:138,553,756...138,575,401
Ensembl chr 5:138,553,756...138,575,675
JBrowse link
G HSPB1 heat shock protein family B (small) member 1 affects expression
multiple interactions
increases expression
ISO Fenofibrate affects the expression of HSPB1 mRNA
PPARA protein affects the reaction [Fenofibrate results in increased expression of HSPB1 mRNA]
CTD PMID:20801182 PMID:21318169 NCBI chr 7:76,302,673...76,304,292
Ensembl chr 7:76,302,673...76,305,813
JBrowse link
G HSPB8 heat shock protein family B (small) member 8 multiple interactions
increases expression
ISO [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of HSPB8 mRNA
Fenofibrate results in increased expression of HSPB8 mRNA
CTD PMID:21318169 NCBI chr12:119,178,931...119,194,746
Ensembl chr12:119,171,555...119,224,855
JBrowse link
G HSPE1 heat shock protein family E (Hsp10) member 1 affects expression ISO Fenofibrate affects the expression of HSPE1 mRNA CTD PMID:20801182 NCBI chr 2:197,500,379...197,503,449
Ensembl chr 2:197,500,140...197,503,449
JBrowse link
G HSPH1 heat shock protein family H (Hsp110) member 1 increases expression
multiple interactions
ISO Fenofibrate results in increased expression of HSPH1 mRNA
PPARA protein affects the reaction [Fenofibrate results in increased expression of HSPH1 mRNA]
CTD PMID:21318169 NCBI chr13:31,134,973...31,162,388
Ensembl chr13:31,134,973...31,162,388
JBrowse link
G HTATIP2 HIV-1 Tat interactive protein 2 increases expression ISO Fenofibrate results in increased expression of HTATIP2 mRNA CTD PMID:25596134 NCBI chr11:20,363,714...20,383,782
Ensembl chr11:20,363,685...20,383,782
JBrowse link
G IARS1 isoleucyl-tRNA synthetase 1 increases expression ISO
EXP
Fenofibrate results in increased expression of IARS1 mRNA CTD PMID:25596134 NCBI chr 9:92,210,207...92,293,697
Ensembl chr 9:92,210,207...92,293,854
JBrowse link
G ICAM1 intercellular adhesion molecule 1 multiple interactions ISO
EXP
Fenofibrate inhibits the reaction [Lipopolysaccharides results in increased expression of ICAM1 mRNA]
dorsomorphin inhibits the reaction [Fenofibrate inhibits the reaction [ALB protein modified form results in increased expression of ICAM1 mRNA]]; Fenofibrate inhibits the reaction [ALB protein modified form results in increased expression of ICAM1 mRNA]
CTD PMID:20580385 PMID:21300114 NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615
JBrowse link
G ID2 inhibitor of DNA binding 2 decreases expression ISO Fenofibrate results in decreased expression of ID2 mRNA CTD PMID:11798191 NCBI chr 2:8,682,056...8,684,461
Ensembl chr 2:8,678,845...8,684,461
JBrowse link
G IDH3B isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta increases expression EXP Fenofibrate results in increased expression of IDH3B mRNA CTD PMID:24752549 NCBI chr20:2,658,395...2,664,216
Ensembl chr20:2,658,393...2,664,219
JBrowse link
G IFFO1 intermediate filament family orphan 1 increases expression ISO Fenofibrate results in increased expression of IFFO1 mRNA CTD PMID:16707586 NCBI chr12:6,538,961...6,556,042
Ensembl chr12:6,538,961...6,556,073
JBrowse link
G IFNG interferon gamma multiple interactions ISO Fenofibrate results in decreased susceptibility to [IFNG protein co-treated with IL1B protein] CTD PMID:20631892 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740
JBrowse link
G IGF2R insulin like growth factor 2 receptor decreases expression ISO Fenofibrate results in decreased expression of IGF2R mRNA CTD PMID:25596134 NCBI chr 6:159,969,082...160,111,504
Ensembl chr 6:159,969,082...160,113,507
JBrowse link
G IL12B interleukin 12B multiple interactions ISO Fenofibrate inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein] CTD PMID:15968640 NCBI chr 5:159,314,780...159,330,487
Ensembl chr 5:159,314,780...159,330,863
JBrowse link
G IL17RB interleukin 17 receptor B decreases expression ISO Fenofibrate results in decreased expression of IL17RB mRNA CTD PMID:25596134 NCBI chr 3:53,846,568...53,865,794
Ensembl chr 3:53,846,568...53,865,794
JBrowse link
G IL1B interleukin 1 beta multiple interactions ISO
EXP
[Fenofibrate co-treated with Alitretinoin] inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]; Fenofibrate inhibits the reaction [Cyclophosphamide results in increased expression of IL1B protein]; Fenofibrate inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; Fenofibrate inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]; Fenofibrate inhibits the reaction [triptolide results in increased expression of IL1B mRNA]
Fenofibrate affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA]; Fenofibrate inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of CD36 mRNA]; Fenofibrate inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein]
Fenofibrate inhibits the reaction [Doxorubicin results in increased expression of IL1B protein]; Fenofibrate promotes the reaction [Pioglitazone inhibits the reaction [Doxorubicin results in increased expression of IL1B protein]]; Fenofibrate results in decreased susceptibility to [IFNG protein co-treated with IL1B protein]; Pioglitazone promotes the reaction [Fenofibrate inhibits the reaction [Doxorubicin results in increased expression of IL1B protein]]
CTD PMID:15968640 PMID:20631892 PMID:21300114 PMID:31241159 PMID:32613381 More... NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816
JBrowse link
G IL6 interleukin 6 multiple interactions
affects response to substance
ISO
EXP
[Fenofibrate co-treated with Alitretinoin] inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]; Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of IL6 mRNA]; Fenofibrate inhibits the reaction [Cyclophosphamide results in increased expression of IL6 protein]; Fenofibrate inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; Fenofibrate inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]; Fenofibrate inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]; Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of IL6 mRNA]; Fenofibrate inhibits the reaction [triptolide results in increased expression of IL6 mRNA]; Fenofibrate inhibits the reaction [tyloxapol results in increased expression of IL6 mRNA]; Fenofibrate promotes the reaction [Dextran Sulfate results in increased expression of IL6 protein]; NR0B2 protein inhibits the reaction [Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of IL6 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of IL6 mRNA]]
IL6 promoter polymorphism affects the susceptibility to Fenofibrate
CTD PMID:15968640 PMID:16607077 PMID:19593819 PMID:21300114 PMID:25035112 More... NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002
JBrowse link
G INS insulin multiple interactions EXP Fenofibrate affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA]; Fenofibrate inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of CD36 mRNA]; Fenofibrate inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein] CTD PMID:32613381 NCBI chr11:2,159,779...2,161,209
Ensembl chr11:2,159,779...2,161,221
JBrowse link
G INS-IGF2 INS-IGF2 readthrough multiple interactions ISO Fenofibrate inhibits the reaction [Fructose results in increased secretion of INS1 protein] CTD PMID:26973390 NCBI chr11:2,129,117...2,161,209
Ensembl chr11:2,132,538...2,161,209
JBrowse link
G INSIG1 insulin induced gene 1 decreases expression EXP Fenofibrate results in decreased expression of INSIG1 mRNA CTD PMID:25572481 NCBI chr 7:155,297,878...155,310,235
Ensembl chr 7:155,297,776...155,310,235
JBrowse link
G INSIG2 insulin induced gene 2 decreases expression ISO Fenofibrate results in decreased expression of INSIG2 mRNA CTD PMID:25596134 NCBI chr 2:118,088,471...118,110,997
Ensembl chr 2:118,088,452...118,110,997
JBrowse link
G IRAK2 interleukin 1 receptor associated kinase 2 increases expression EXP Fenofibrate results in increased expression of IRAK2 mRNA CTD PMID:25572481 NCBI chr 3:10,164,919...10,243,745
Ensembl chr 3:10,164,919...10,243,745
JBrowse link
G IRF7 interferon regulatory factor 7 increases expression EXP Fenofibrate results in increased expression of IRF7 mRNA CTD PMID:25572481 NCBI chr11:612,555...615,950
Ensembl chr11:612,553...615,983
JBrowse link
G ITCH itchy E3 ubiquitin protein ligase multiple interactions
decreases expression
ISO PPARA protein affects the reaction [Fenofibrate results in decreased expression of ITCH mRNA] CTD PMID:21318169 NCBI chr20:34,363,273...34,511,773
Ensembl chr20:34,363,235...34,511,773
JBrowse link
G ITFG2 integrin alpha FG-GAP repeat containing 2 increases expression EXP Fenofibrate results in increased expression of ITFG2 mRNA CTD PMID:25596134 NCBI chr12:2,812,668...2,859,791
Ensembl chr12:2,812,622...2,859,791
JBrowse link
G ITGB1 integrin subunit beta 1 decreases expression ISO Fenofibrate results in decreased expression of ITGB1 mRNA CTD PMID:25596134 NCBI chr10:32,900,318...32,958,230
Ensembl chr10:32,887,273...33,005,792
JBrowse link
G ITGB3 integrin subunit beta 3 affects expression ISO Fenofibrate affects the expression of ITGB3 mRNA CTD PMID:20801182 NCBI chr17:47,253,827...47,313,743
Ensembl chr17:47,253,827...47,313,743
JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP
ISO
Fenofibrate inhibits the reaction [Glucose results in increased expression of JUN protein]
[Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of JUN mRNA; Fenofibrate affects the reaction [[AHR protein affects the susceptibility to AGT protein] which affects the expression of JUN mRNA]
CTD PMID:16600694 PMID:18978307 PMID:31016362 NCBI chr 1:58,780,791...58,784,047
Ensembl chr 1:58,776,845...58,784,048
JBrowse link
G KCNK13 potassium two pore domain channel subfamily K member 13 increases expression EXP Fenofibrate results in increased expression of KCNK13 mRNA CTD PMID:25572481 PMID:25596134 NCBI chr14:90,061,994...90,185,853
Ensembl chr14:90,061,994...90,185,853
JBrowse link
G KEAP1 kelch like ECH associated protein 1 multiple interactions ISO Fenofibrate inhibits the reaction [tyloxapol results in increased expression of KEAP1 protein] CTD PMID:36905866 NCBI chr19:10,486,125...10,503,356
Ensembl chr19:10,486,125...10,503,558
JBrowse link
G KIF22 kinesin family member 22 increases expression ISO Fenofibrate results in increased expression of KIF22 mRNA CTD PMID:32741897 NCBI chr16:29,790,751...29,805,385
Ensembl chr16:29,790,727...29,805,385
JBrowse link
G KIFC1 kinesin family member C1 increases expression ISO Fenofibrate results in increased expression of KIFC1 mRNA CTD PMID:32741897 NCBI chr 6:33,391,461...33,409,896
Ensembl chr 6:33,391,823...33,409,896
JBrowse link
G KLF10 KLF transcription factor 10 decreases expression
increases expression
ISO
EXP
Fenofibrate results in decreased expression of KLF10 mRNA
Fenofibrate results in increased expression of KLF10 mRNA
CTD PMID:11798191 PMID:25572481 NCBI chr 8:102,648,784...102,655,725
Ensembl chr 8:102,648,784...102,655,725
JBrowse link
G KLF11 KLF transcription factor 11 increases expression EXP Fenofibrate results in increased expression of KLF11 mRNA CTD PMID:25572481 NCBI chr 2:10,043,550...10,054,836
Ensembl chr 2:10,042,849...10,054,836
JBrowse link
G KRT18 keratin 18 multiple interactions ISO [Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of KRT18 protein CTD PMID:18978307 NCBI chr12:52,948,855...52,952,906
Ensembl chr12:52,948,871...52,952,906
JBrowse link
G KRT23 keratin 23 increases expression ISO Fenofibrate results in increased expression of KRT23 mRNA CTD PMID:32741897 NCBI chr17:40,922,700...40,937,646
Ensembl chr17:40,922,700...40,937,646
JBrowse link
G KRT8 keratin 8 multiple interactions ISO [Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of KRT8 protein CTD PMID:18978307 NCBI chr12:52,897,191...52,949,860
Ensembl chr12:52,897,187...52,949,954
JBrowse link
G KRTAP1-5 keratin associated protein 1-5 increases expression ISO Fenofibrate results in increased expression of KRTAP1-5 mRNA CTD PMID:32741897 NCBI chr17:41,026,026...41,027,208
Ensembl chr17:41,026,026...41,027,208
JBrowse link
G LAMA4 laminin subunit alpha 4 increases expression EXP Fenofibrate results in increased expression of LAMA4 mRNA CTD PMID:25572481 NCBI chr 6:112,107,931...112,254,985
Ensembl chr 6:112,107,931...112,254,939
JBrowse link
G LARS1 leucyl-tRNA synthetase 1 increases expression
decreases expression
EXP
ISO
Fenofibrate results in increased expression of LARS1 mRNA
Fenofibrate results in decreased expression of LARS1 mRNA
CTD PMID:25596134 NCBI chr 5:146,113,034...146,182,650
Ensembl chr 5:146,110,566...146,182,696
JBrowse link
G LBH LBH regulator of WNT signaling pathway increases expression EXP Fenofibrate results in increased expression of LBH mRNA CTD PMID:25572481 NCBI chr 2:30,231,534...30,260,028
Ensembl chr 2:30,231,534...30,323,730
JBrowse link
G LDHB lactate dehydrogenase B increases expression EXP Fenofibrate results in increased expression of LDHB mRNA CTD PMID:25572481 NCBI chr12:21,635,342...21,657,842
Ensembl chr12:21,635,342...21,757,857
JBrowse link
G LEP leptin multiple interactions ISO
EXP
[Fenofibrate co-treated with resveratrol] inhibits the reaction [Fructose results in increased expression of LEP mRNA]; Fenofibrate inhibits the reaction [Fructose results in increased expression of LEP mRNA]
Fenofibrate inhibits the reaction [Arsenic Trioxide results in decreased expression of and results in decreased secretion of LEP protein]
CTD PMID:26973390 PMID:32929351 NCBI chr 7:128,241,278...128,257,629
Ensembl chr 7:128,241,278...128,257,629
JBrowse link
G LGALS1 galectin 1 increases expression ISO Fenofibrate results in increased expression of LGALS1 mRNA CTD PMID:11798191 NCBI chr22:37,675,636...37,679,802
Ensembl chr22:37,675,636...37,679,802
JBrowse link
G LIFR LIF receptor subunit alpha decreases expression ISO Fenofibrate results in decreased expression of LIFR mRNA CTD PMID:11798191 NCBI chr 5:38,474,668...38,608,403
Ensembl chr 5:38,474,668...38,608,354
JBrowse link
G LMCD1 LIM and cysteine rich domains 1 affects expression ISO Fenofibrate affects the expression of LMCD1 mRNA CTD PMID:25596134 NCBI chr 3:8,501,823...8,574,668
Ensembl chr 3:8,501,807...8,574,668
JBrowse link
G LNX1 ligand of numb-protein X 1 multiple interactions
decreases expression
ISO PPARA protein affects the reaction [Fenofibrate results in decreased expression of LNX1 mRNA] CTD PMID:21318169 NCBI chr 4:53,459,301...53,652,477
Ensembl chr 4:53,459,301...53,701,405
JBrowse link
G LPCAT2 lysophosphatidylcholine acyltransferase 2 increases expression EXP Fenofibrate results in increased expression of LPCAT2 mRNA CTD PMID:25572481 NCBI chr16:55,509,072...55,586,666
Ensembl chr16:55,509,072...55,586,666
JBrowse link
G LPCAT3 lysophosphatidylcholine acyltransferase 3 increases expression EXP Fenofibrate results in increased expression of LPCAT3 mRNA CTD PMID:25572481 NCBI chr12:6,976,185...7,018,476
Ensembl chr12:6,976,185...7,018,477
JBrowse link
G LPL lipoprotein lipase increases expression
multiple interactions
increases activity
ISO
EXP
Fenofibrate results in increased expression of LPL mRNA; Fenofibrate results in increased expression of LPL protein
PPARA protein promotes the reaction [Fenofibrate results in increased expression of LPL protein]
PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of LPL mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of LPL protein]
Fenofibrate inhibits the reaction [Pyrazinamide results in decreased expression of LPL mRNA]
Fenofibrate results in increased activity of LPL protein
CTD PMID:8593127 PMID:11798191 PMID:16595124 PMID:24752549 PMID:27071702 NCBI chr 8:19,939,253...19,967,259
Ensembl chr 8:19,901,717...19,967,259
JBrowse link
G LRRC31 leucine rich repeat containing 31 increases expression EXP Fenofibrate results in increased expression of LRRC31 mRNA CTD PMID:25572481 NCBI chr 3:169,839,172...169,869,935
Ensembl chr 3:169,839,172...169,869,935
JBrowse link
G LRSAM1 leucine rich repeat and sterile alpha motif containing 1 multiple interactions
decreases expression
ISO PPARA protein affects the reaction [Fenofibrate results in decreased expression of LRSAM1 mRNA] CTD PMID:21318169 NCBI chr 9:127,451,486...127,503,501
Ensembl chr 9:127,451,489...127,503,499
JBrowse link
G LSS lanosterol synthase increases expression
multiple interactions
ISO Fenofibrate results in increased expression of LSS mRNA
NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of LSS mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of LSS mRNA]
CTD PMID:23063693 NCBI chr21:46,188,446...46,228,774
Ensembl chr21:46,188,141...46,228,824
JBrowse link
G LTN1 listerin E3 ubiquitin protein ligase 1 decreases expression ISO Fenofibrate results in decreased expression of LTN1 mRNA CTD PMID:25596134 NCBI chr21:28,928,144...28,992,877
Ensembl chr21:28,928,144...28,992,956
JBrowse link
G LY6D lymphocyte antigen 6 family member D increases expression ISO Fenofibrate results in increased expression of LY6D mRNA CTD PMID:17118139 NCBI chr 8:142,784,882...142,786,539
Ensembl chr 8:142,784,882...142,786,539
JBrowse link
G LYRM1 LYR motif containing 1 increases expression EXP Fenofibrate results in increased expression of LYRM1 mRNA CTD PMID:25572481 NCBI chr16:20,899,882...20,925,006
Ensembl chr16:20,899,868...20,925,006
JBrowse link
G LYZ lysozyme decreases expression ISO Fenofibrate results in decreased expression of LYZ2 mRNA CTD PMID:11798191 NCBI chr12:69,348,381...69,354,234
Ensembl chr12:69,348,381...69,354,234
JBrowse link
G MAFG MAF bZIP transcription factor G decreases expression
increases expression
ISO
EXP
Fenofibrate results in decreased expression of MAFG mRNA
Fenofibrate results in increased expression of MAFG mRNA
CTD PMID:25596134 NCBI chr17:81,918,270...81,931,244
Ensembl chr17:81,918,270...81,927,735
JBrowse link
G MAN1A1 mannosidase alpha class 1A member 1 decreases expression ISO Fenofibrate results in decreased expression of MAN1A mRNA CTD PMID:16707586 NCBI chr 6:119,177,205...119,350,605
Ensembl chr 6:119,177,205...119,349,761
JBrowse link
G MAN1A2 mannosidase alpha class 1A member 2 decreases expression ISO Fenofibrate results in decreased expression of MAN1A2 mRNA CTD PMID:25596134 NCBI chr 1:117,367,449...117,528,872
Ensembl chr 1:117,367,449...117,528,872
JBrowse link
G MAOB monoamine oxidase B multiple interactions ISO [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of MAOB mRNA CTD PMID:18253720 NCBI chr  X:43,766,610...43,882,450
Ensembl chr  X:43,766,610...43,882,450
JBrowse link
G MAP1LC3A microtubule associated protein 1 light chain 3 alpha increases expression
multiple interactions
ISO Fenofibrate results in increased expression of MAP1LC3A mRNA
[PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of MAP1LC3A mRNA
CTD PMID:21318169 NCBI chr20:34,546,844...34,560,345
Ensembl chr20:34,546,854...34,560,345
JBrowse link
G MAP1LC3B microtubule associated protein 1 light chain 3 beta multiple interactions ISO Fenofibrate inhibits the reaction [tyloxapol results in increased lipidation of MAP1LC3B protein] CTD PMID:36905866 NCBI chr16:87,392,336...87,404,774
Ensembl chr16:87,383,953...87,404,779
JBrowse link
G MAP3K13 mitogen-activated protein kinase kinase kinase 13 increases expression ISO Fenofibrate results in increased expression of MAP3K13 mRNA CTD PMID:32741897 NCBI chr 3:185,282,961...185,489,094
Ensembl chr 3:185,282,941...185,489,094
JBrowse link
G MAT2A methionine adenosyltransferase 2A decreases expression EXP Fenofibrate results in decreased expression of MAT2A mRNA CTD PMID:16569247 NCBI chr 2:85,539,168...85,545,281
Ensembl chr 2:85,539,168...85,545,281
JBrowse link
G MC1R melanocortin 1 receptor decreases expression
multiple interactions
ISO Fenofibrate results in decreased expression of MC1R mRNA
[Fenofibrate results in decreased expression of MC1R mRNA] which results in decreased chemical synthesis of Melanins
CTD PMID:23872139 NCBI chr16:89,918,862...89,920,972
Ensembl chr16:89,912,119...89,920,973
JBrowse link
G MDH2 malate dehydrogenase 2 increases expression EXP Fenofibrate results in increased expression of MDH mRNA CTD PMID:24752549 NCBI chr 7:76,048,106...76,067,508
Ensembl chr 7:76,048,051...76,067,508
JBrowse link
G MDM2 MDM2 proto-oncogene decreases expression ISO Fenofibrate results in decreased expression of MDM2 mRNA CTD PMID:25596134 NCBI chr12:68,808,172...68,850,686
Ensembl chr12:68,808,177...68,845,544
JBrowse link
G ME1 malic enzyme 1 affects expression
increases expression
multiple interactions
ISO Fenofibrate affects the expression of ME1 mRNA
Fenofibrate results in increased expression of ME1 mRNA
NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ME1 mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ME1 mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ME1 mRNA]
CTD PMID:20801182 PMID:23063693 PMID:25596134 PMID:27071702 NCBI chr 6:83,210,402...83,431,051
Ensembl chr 6:83,210,402...83,431,051
JBrowse link
G MERTK MER proto-oncogene, tyrosine kinase increases expression EXP Fenofibrate results in increased expression of MERTK mRNA CTD PMID:25572481 NCBI chr 2:111,898,607...112,029,561
Ensembl chr 2:111,898,607...112,029,561
JBrowse link
G MFN2 mitofusin 2 multiple interactions EXP Fenofibrate inhibits the reaction [[Fructose co-treated with Palmitic Acid] results in decreased expression of MFN2 protein] CTD PMID:32730863 NCBI chr 1:11,980,444...12,013,508
Ensembl chr 1:11,980,181...12,015,211
JBrowse link
G MFSD2A MFSD2 lysolipid transporter A, lysophospholipid decreases expression EXP Fenofibrate results in decreased expression of MFSD2A mRNA CTD PMID:25572481 NCBI chr 1:39,955,145...39,969,956
Ensembl chr 1:39,955,112...39,969,968
JBrowse link
G MGLL monoglyceride lipase increases expression ISO Fenofibrate results in increased expression of MGLL mRNA CTD PMID:11798191 PMID:17118139 PMID:27665778 NCBI chr 3:127,689,066...127,823,185
Ensembl chr 3:127,689,062...128,052,190
JBrowse link
G MGMT O-6-methylguanine-DNA methyltransferase multiple interactions
increases expression
ISO [Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of MGMT mRNA
Fenofibrate results in increased expression of MGMT mRNA
CTD PMID:17264098 PMID:18253720 NCBI chr10:129,467,241...129,770,983
Ensembl chr10:129,467,190...129,770,983
JBrowse link
G MGRN1 mahogunin ring finger 1 increases expression
multiple interactions
ISO Fenofibrate results in increased expression of MGRN1 mRNA
[PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of MGRN1 mRNA
CTD PMID:21318169 NCBI chr16:4,624,826...4,690,972
Ensembl chr16:4,616,493...4,690,974
JBrowse link
G MGST3 microsomal glutathione S-transferase 3 increases expression ISO Fenofibrate results in increased expression of MGST3 mRNA CTD PMID:11798191 NCBI chr 1:165,631,234...165,656,136
Ensembl chr 1:165,631,213...165,661,796
JBrowse link
G MITF melanocyte inducing transcription factor decreases expression ISO Fenofibrate results in decreased expression of MITF mRNA; Fenofibrate results in decreased expression of MITF protein CTD PMID:23872139 NCBI chr 3:69,739,464...69,968,332
Ensembl chr 3:69,739,456...69,968,336
JBrowse link
G MKI67 marker of proliferation Ki-67 increases expression ISO Fenofibrate results in increased expression of MKI67 mRNA; Fenofibrate results in increased expression of MKI67 protein CTD PMID:17264098 PMID:32741897 NCBI chr10:128,096,659...128,126,423
Ensembl chr10:128,096,659...128,126,423
JBrowse link
G MLH1 mutL homolog 1 multiple interactions
increases expression
ISO [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of MLH1 mRNA; [Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of MLH1 mRNA
Fenofibrate results in increased expression of MLH1 mRNA
CTD PMID:17264098 PMID:18253720 PMID:18775883 NCBI chr 3:36,993,466...37,050,846
Ensembl chr 3:36,993,226...37,050,896
JBrowse link
G MLYCD malonyl-CoA decarboxylase multiple interactions ISO [Fenofibrate co-treated with resveratrol] inhibits the reaction [Fructose results in decreased expression of MLYCD mRNA]; Fenofibrate inhibits the reaction [Fructose results in decreased expression of MLYCD mRNA]; Fenofibrate promotes the reaction [PPARA protein results in increased expression of MLYCD mRNA] CTD PMID:14641110 PMID:26973390 NCBI chr16:83,899,115...83,927,031
Ensembl chr16:83,899,115...83,951,445
JBrowse link
G MMD monocyte to macrophage differentiation associated increases expression EXP Fenofibrate results in increased expression of MMD mRNA CTD PMID:25572481 NCBI chr17:55,392,622...55,421,835
Ensembl chr17:55,392,622...55,421,924
JBrowse link
G MMP1 matrix metallopeptidase 1 decreases expression EXP Fenofibrate results in decreased expression of MMP1 protein CTD PMID:25545733 NCBI chr11:102,789,919...102,798,160
Ensembl chr11:102,789,401...102,798,160
JBrowse link
G MMP19 matrix metallopeptidase 19 increases expression ISO Fenofibrate results in increased expression of MMP19 mRNA CTD PMID:25596134 NCBI chr12:55,835,433...55,842,936
Ensembl chr12:55,835,433...55,842,966
JBrowse link
G MMP2 matrix metallopeptidase 2 decreases expression EXP Fenofibrate results in decreased expression of MMP2 protein CTD PMID:25545733 NCBI chr16:55,478,830...55,506,691
Ensembl chr16:55,389,700...55,506,691
JBrowse link
G MMP7 matrix metallopeptidase 7 decreases expression EXP Fenofibrate results in decreased expression of MMP7 protein CTD PMID:25545733 NCBI chr11:102,520,508...102,530,747
Ensembl chr11:102,520,508...102,530,750
JBrowse link
G MMP9 matrix metallopeptidase 9 multiple interactions
decreases expression
EXP Fenofibrate inhibits the reaction [Dinoprostone results in increased expression of MMP9 mRNA]; Fenofibrate inhibits the reaction [Dinoprostone results in increased secretion of MMP9 protein]; Fenofibrate inhibits the reaction [Lipopolysaccharides results in increased secretion of MMP9 protein]
Fenofibrate results in decreased expression of MMP9 protein
CTD PMID:19880272 PMID:21075133 PMID:25545733 NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561
JBrowse link
G MRAP melanocortin 2 receptor accessory protein increases expression ISO Fenofibrate results in increased expression of MRAP mRNA CTD PMID:11798191 NCBI chr21:32,291,813...32,314,784
Ensembl chr21:32,291,813...32,314,784
JBrowse link
G MS4A10 membrane spanning 4-domains A10 decreases expression EXP Fenofibrate results in decreased expression of MS4A10 mRNA CTD PMID:25572481 NCBI chr11:60,785,333...60,801,305
Ensembl chr11:60,785,333...60,801,305
JBrowse link
G MSC musculin decreases expression ISO Fenofibrate results in decreased expression of MSC mRNA CTD PMID:25596134 NCBI chr 8:71,841,560...71,844,412
Ensembl chr 8:71,841,560...71,844,412
JBrowse link
G MSMO1 methylsterol monooxygenase 1 affects expression ISO Fenofibrate affects the expression of MSMO1 mRNA CTD PMID:20801182 NCBI chr 4:165,327,669...165,343,164
Ensembl chr 4:165,327,667...165,343,164
JBrowse link
G MTTP microsomal triglyceride transfer protein increases expression ISO Fenofibrate results in increased expression of MTTP mRNA CTD PMID:32741897 NCBI chr 4:99,564,130...99,623,997
Ensembl chr 4:99,564,081...99,623,997
JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor multiple interactions
increases expression
ISO [Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of MYC mRNA
Fenofibrate results in increased expression of MYC mRNA
CTD PMID:18978307 PMID:32741897 NCBI chr 8:127,735,434...127,742,951
Ensembl chr 8:127,735,434...127,742,951
JBrowse link
G MYLK myosin light chain kinase decreases expression EXP Fenofibrate results in decreased expression of MYLK mRNA CTD PMID:25572481 NCBI chr 3:123,610,049...123,884,332
Ensembl chr 3:123,610,049...123,884,332
JBrowse link
G N4BP2L1 NEDD4 binding protein 2 like 1 increases expression EXP Fenofibrate results in increased expression of N4BP2L1 mRNA CTD PMID:25572481 NCBI chr13:32,400,723...32,429,615
Ensembl chr13:32,400,723...32,428,311
JBrowse link
G NACC1 nucleus accumbens associated 1 increases expression ISO Fenofibrate results in increased expression of NACC1 mRNA CTD PMID:17264098 NCBI chr19:13,116,852...13,141,147
Ensembl chr19:13,116,862...13,141,147
JBrowse link
G NAMPT nicotinamide phosphoribosyltransferase increases expression ISO Fenofibrate results in increased expression of NAMPT mRNA CTD PMID:25596134 NCBI chr 7:106,248,298...106,285,888
Ensembl chr 7:106,248,298...106,285,966
JBrowse link
G NARS1 asparaginyl-tRNA synthetase 1 affects expression ISO Fenofibrate affects the expression of NARS1 mRNA CTD PMID:25596134 NCBI chr18:57,600,656...57,621,836
Ensembl chr18:57,600,656...57,622,213
JBrowse link
G NBN nibrin multiple interactions
increases expression
ISO [Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of NBN mRNA
Fenofibrate results in increased expression of NBN mRNA
CTD PMID:17264098 PMID:18253720 PMID:18775883 NCBI chr 8:89,933,331...89,984,667
Ensembl chr 8:89,924,515...90,003,228
JBrowse link
G NCEH1 neutral cholesterol ester hydrolase 1 increases expression ISO Fenofibrate results in increased expression of NCEH1 mRNA CTD PMID:27665778 NCBI chr 3:172,630,249...172,711,067
Ensembl chr 3:172,630,249...172,711,218
JBrowse link
G NDUFAB1 NADH:ubiquinone oxidoreductase subunit AB1 increases expression ISO Fenofibrate results in increased expression of NDUFAB1 mRNA CTD PMID:11798191 NCBI chr16:23,581,014...23,596,316
Ensembl chr16:23,581,014...23,596,316
JBrowse link
G NEAT1 nuclear paraspeckle assembly transcript 1 increases expression EXP Fenofibrate results in increased expression of NEAT1 mRNA; Fenofibrate results in increased expression of NEAT1 mRNA alternative form CTD PMID:31311324 NCBI chr11:65,422,798...65,445,540
Ensembl chr11:65,422,278...65,445,540
JBrowse link
G NEDD4 NEDD4 E3 ubiquitin protein ligase increases expression
multiple interactions
ISO Fenofibrate results in increased expression of NEDD4 mRNA
PPARA protein affects the reaction [Fenofibrate results in increased expression of NEDD4 mRNA]
CTD PMID:21318169 NCBI chr15:55,826,917...55,993,612
Ensembl chr15:55,826,922...55,993,660
JBrowse link
G NEDD9 neural precursor cell expressed, developmentally down-regulated 9 decreases expression EXP
ISO
Fenofibrate results in decreased expression of NEDD9 mRNA CTD PMID:25596134 NCBI chr 6:11,183,298...11,382,348
Ensembl chr 6:11,183,298...11,382,348
JBrowse link
G NFATC4 nuclear factor of activated T cells 4 multiple interactions ISO EDN1 protein promotes the reaction [Fenofibrate promotes the reaction [NFATC4 protein binds to PPARA protein]]; Fenofibrate inhibits the reaction [EDN1 protein promotes the reaction [NFATC4 protein binds to GATA4 protein]]; Fenofibrate inhibits the reaction [EDN1 protein promotes the reaction [NFATC4 protein binds to NPPB promoter]]; Fenofibrate promotes the reaction [NFATC4 protein binds to PPARA protein]; PPARA mutant form inhibits the reaction [Fenofibrate inhibits the reaction [EDN1 protein promotes the reaction [NFATC4 protein binds to GATA4 protein]]] CTD PMID:22198280 NCBI chr14:24,366,911...24,379,604
Ensembl chr14:24,365,673...24,379,604
JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 multiple interactions
increases activity
decreases expression
affects activity
ISO
EXP
[Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of NFE2L2 protein
Fenofibrate inhibits the reaction [[Fructose co-treated with Palmitic Acid] results in decreased expression of NFE2L2 protein]
Fenofibrate inhibits the reaction [triptolide results in increased expression of NFE2L2 mRNA]; Fenofibrate inhibits the reaction [triptolide results in increased expression of NFE2L2 protein]
Fenofibrate results in increased activity of NFE2L2 protein
Fenofibrate results in decreased expression of NFE2L2 mRNA
Fenofibrate affects the activity of NFE2L2 protein
CTD PMID:18775883 PMID:25596134 PMID:30114225 PMID:30203046 PMID:31241159 More... NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756
JBrowse link
G NFKB1 nuclear factor kappa B subunit 1 multiple interactions
affects localization
EXP Fenofibrate inhibits the reaction [ALB protein modified form results in increased expression of NFKB1 protein]
Fenofibrate affects the localization of NFKB1 protein
CTD PMID:20580385 PMID:25545733 NCBI chr 4:102,501,359...102,617,302
Ensembl chr 4:102,501,330...102,617,302
JBrowse link
G NFKBIA NFKB inhibitor alpha multiple interactions
decreases expression
EXP Fenofibrate inhibits the reaction [ALB protein modified form results in increased degradation of NFKBIA protein]
Fenofibrate results in decreased expression of NFKBIA protein modified form
CTD PMID:20580385 PMID:25545733 NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,079...35,404,749
JBrowse link
G NFKBIB NFKB inhibitor beta multiple interactions ISO [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of NFKBIB mRNA; [Fenofibrate co-treated with Sodium Glutamate] results in increased expression of NFKBIB mRNA CTD PMID:18253720 PMID:21999347 NCBI chr19:38,899,666...38,908,889
Ensembl chr19:38,899,700...38,908,893
JBrowse link
G NIM1K NIM1 serine/threonine protein kinase increases expression ISO Fenofibrate results in increased expression of NIM1K mRNA CTD PMID:32741897 NCBI chr 5:43,192,225...43,280,850
Ensembl chr 5:43,192,071...43,280,850
JBrowse link
G NINJ1 ninjurin 1 affects expression ISO Fenofibrate affects the expression of NINJ1 mRNA CTD PMID:25596134 NCBI chr 9:93,121,496...93,134,251
Ensembl chr 9:93,121,496...93,134,251
JBrowse link
G NLRP3 NLR family pyrin domain containing 3 multiple interactions ISO Fenofibrate inhibits the reaction [Cyclophosphamide results in increased expression of NLRP3 protein] CTD PMID:38278497 NCBI chr 1:247,416,077...247,448,817
Ensembl chr 1:247,332,331...247,449,108
JBrowse link
G NMUR1 neuromedin U receptor 1 decreases expression ISO Fenofibrate results in decreased expression of NMUR1 mRNA CTD PMID:25596134 NCBI chr 2:231,518,455...231,530,445
Ensembl chr 2:231,523,187...231,530,445
JBrowse link
G NNMT nicotinamide N-methyltransferase multiple interactions ISO [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of NNMT mRNA CTD PMID:18253720 NCBI chr11:114,257,806...114,313,536
Ensembl chr11:114,257,787...114,313,536
JBrowse link
G NOS2 nitric oxide synthase 2 multiple interactions ISO Fenofibrate inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]
[Fenofibrate co-treated with Sodium Glutamate] results in increased expression of NOS2 mRNA; [Fenofibrate co-treated with Sodium Glutamate] results in increased expression of NOS2 protein
CTD PMID:21300114 PMID:21999347 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529
JBrowse link
G NOS3 nitric oxide synthase 3 multiple interactions
increases phosphorylation
increases activity
EXP dorsomorphin inhibits the reaction [Fenofibrate results in increased activity of NOS3 protein]; Fenofibrate inhibits the reaction [Wortmannin results in decreased phosphorylation of NOS3 protein]; PRKAA1 protein affects the reaction [Fenofibrate results in increased activity of NOS3 protein]
Fenofibrate results in increased phosphorylation of NOS3 protein
CTD PMID:16442496 PMID:20580385 NCBI chr 7:150,991,017...151,014,588
Ensembl chr 7:150,991,017...151,014,588
JBrowse link
G NOTCH1 notch receptor 1 multiple interactions ISO Fenofibrate inhibits the reaction [triptolide results in increased expression of NOTCH1 mRNA] CTD PMID:31241159 NCBI chr 9:136,494,433...136,546,048
Ensembl chr 9:136,494,433...136,546,048
JBrowse link
G NOTCH3 notch receptor 3 multiple interactions ISO Fenofibrate inhibits the reaction [triptolide results in increased expression of NOTCH3 mRNA]; Fenofibrate inhibits the reaction [triptolide results in increased expression of NOTCH3 protein] CTD PMID:31241159 NCBI chr19:15,159,038...15,200,995
Ensembl chr19:15,159,038...15,200,995
JBrowse link
G NPPA natriuretic peptide A multiple interactions ISO Fenofibrate inhibits the reaction [Doxorubicin results in decreased expression of NPPA mRNA] CTD PMID:17531194 NCBI chr 1:11,845,709...11,847,783
Ensembl chr 1:11,845,709...11,848,345
JBrowse link
G NPPB natriuretic peptide B multiple interactions ISO Fenofibrate inhibits the reaction [EDN1 protein promotes the reaction [NFATC4 protein binds to NPPB promoter]]; Fenofibrate inhibits the reaction [EDN1 protein results in increased expression of NPPB mRNA]; PPARA mutant form inhibits the reaction [Fenofibrate inhibits the reaction [EDN1 protein results in increased expression of NPPB mRNA]] CTD PMID:22198280 NCBI chr 1:11,857,464...11,858,945
Ensembl chr 1:11,857,464...11,858,945
JBrowse link
G NR0B2 nuclear receptor subfamily 0 group B member 2 multiple interactions
increases expression
EXP
ISO
Dactinomycin inhibits the reaction [Fenofibrate results in increased expression of NR0B2 mRNA]; dorsomorphin inhibits the reaction [Fenofibrate results in increased expression of NR0B2 mRNA]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [NR4A1 protein results in increased expression of SERPINE1 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [SMAD3 protein results in increased expression of SERPINE1 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [SMAD4 protein results in increased expression of SERPINE1 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of SERPINE1 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [TNF protein results in increased expression of SERPINE1 mRNA]]; pyrazolanthrone inhibits the reaction [Fenofibrate results in increased expression of NR0B2 mRNA]
[Methionine deficiency co-treated with Choline deficiency co-treated with Fenofibrate] results in increased expression of NR0B2 mRNA; NR0B2 protein inhibits the reaction [Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]]; NR0B2 protein inhibits the reaction [Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of IL6 mRNA]]; NR0B2 protein inhibits the reaction [Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of SERPINE1 mRNA]]; NR0B2 protein inhibits the reaction [Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of TIMP1 mRNA]]; NR0B2 protein promotes the reaction [[Methionine deficiency co-treated with Choline deficiency co-treated with Fenofibrate] results in increased expression of CYP4A14 mRNA]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of COL1A1 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of FAS mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of IL6 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of SERPINE1 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of SREBF1 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of TGFB1 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of TIMP1 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of TNF mRNA]]
Fenofibrate results in increased expression of NR0B2 mRNA; Fenofibrate results in increased expression of NR0B2 protein
CTD PMID:19593819 NCBI chr 1:26,911,489...26,913,975
Ensembl chr 1:26,911,489...26,913,975
JBrowse link
G NR1H2 nuclear receptor subfamily 1 group H member 2 increases expression
multiple interactions
EXP
ISO
Fenofibrate results in increased expression of NR1H2 mRNA
NR1H2 gene mutant form affects the reaction [Fenofibrate results in increased expression of ACACB mRNA]; NR1H2 gene mutant form affects the reaction [Fenofibrate results in increased expression of SCD1 mRNA]; NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACACA mRNA]; NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACOX1 mRNA]; NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of CYP4A10 mRNA]; NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of CYP4A14 mRNA]; NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ELOVL6 mRNA]; NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of FASN mRNA]; NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of FDFT1 mRNA]; NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of HMGCR mRNA]; NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of LSS mRNA]; NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ME1 mRNA]; NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of PPARA mRNA]; NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of SCD2 mRNA]; NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of SQLE mRNA]; NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of SREBF1 mRNA]
CTD PMID:19201410 PMID:23063693 NCBI chr19:50,376,457...50,383,388
Ensembl chr19:50,329,653...50,383,388
JBrowse link
G NR1H3 nuclear receptor subfamily 1 group H member 3 increases expression
multiple interactions
affects response to substance
EXP
ISO
Fenofibrate results in increased expression of NR1H3 mRNA
NR1H3 gene mutant form affects the reaction [Fenofibrate results in increased expression of ACACB mRNA]; NR1H3 gene mutant form affects the reaction [Fenofibrate results in increased expression of SCD1 mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACACA mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACOX1 mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of CYP4A10 mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of CYP4A14 mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ELOVL6 mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of FASN mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of FDFT1 mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of HMGCR mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of LSS mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ME1 mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of PPARA mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of SCD2 mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of SQLE mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of SREBF1 mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of NR1H3 mRNA]
NR1H3 protein affects the susceptibility to Fenofibrate
[Oleic Acid co-treated with Fenofibrate] affects the expression of NR1H3 mRNA; NR1H3 protein affects the reaction [Fenofibrate results in increased expression of PPARA mRNA]
CTD PMID:19201410 PMID:23063693 PMID:24534255 PMID:25949234 NCBI chr11:47,248,300...47,269,033
Ensembl chr11:47,248,300...47,269,033
JBrowse link
G NR1H4 nuclear receptor subfamily 1 group H member 4 multiple interactions
increases expression
EXP
ISO
[Oleic Acid co-treated with Fenofibrate] results in decreased expression of NR1H4 mRNA
fenofibrate increases expression of Nr1h4 mRNA in steatotic liver
CTD
RGD
PMID:24534255 PMID:30257410 RGD:15090799 NCBI chr12:100,473,866...100,564,414
Ensembl chr12:100,473,708...100,564,414
JBrowse link
G NR1I2 nuclear receptor subfamily 1 group I member 2 multiple interactions EXP Fenofibrate binds to and results in increased activity of NR1I2 protein CTD PMID:20024649 NCBI chr 3:119,782,101...119,818,487
Ensembl chr 3:119,780,484...119,818,487
JBrowse link
G NR1I3 nuclear receptor subfamily 1 group I member 3 affects localization
increases activity
multiple interactions
increases expression
ISO
EXP
Fenofibrate affects the localization of NR1I3 protein
Fenofibrate results in increased activity of NR1I3 protein
[Oleic Acid co-treated with Fenofibrate] results in increased expression of NR1I3 mRNA; Fenofibrate binds to and results in increased activity of NR1I3 protein alternative form
Fenofibrate results in increased expression of NR1I3 mRNA
CTD PMID:17962186 PMID:19118567 PMID:24534255 PMID:30203046 PMID:31312845 More... NCBI chr 1:161,229,669...161,238,203
Ensembl chr 1:161,229,666...161,238,244
JBrowse link
G NR4A1 nuclear receptor subfamily 4 group A member 1 multiple interactions EXP Fenofibrate inhibits the reaction [NR4A1 protein results in increased expression of SERPINE1 mRNA]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [NR4A1 protein results in increased expression of SERPINE1 mRNA]] CTD PMID:19593819 NCBI chr12:52,022,832...52,059,503
Ensembl chr12:52,022,832...52,059,507
JBrowse link
G NREP neuronal regeneration related protein decreases expression EXP Fenofibrate results in decreased expression of NREP mRNA CTD PMID:25596134 NCBI chr 5:111,728,802...111,976,932
Ensembl chr 5:111,662,621...111,997,464
JBrowse link
G NSDHL NAD(P) dependent steroid dehydrogenase-like increases expression ISO Fenofibrate results in increased expression of NSDHL mRNA CTD PMID:11798191 NCBI chr  X:152,831,063...152,869,729
Ensembl chr  X:152,830,967...152,869,729
JBrowse link
G NTPCR nucleoside-triphosphatase, cancer-related affects expression ISO Fenofibrate affects the expression of NTPCR mRNA CTD PMID:25596134 NCBI chr 1:232,950,611...232,983,882
Ensembl chr 1:232,950,605...232,983,882
JBrowse link
G NUAK1 NUAK family kinase 1 decreases expression EXP Fenofibrate results in decreased expression of NUAK1 mRNA CTD PMID:25596134 NCBI chr12:106,063,345...106,138,954
Ensembl chr12:106,063,345...106,138,954
JBrowse link
G OASL 2'-5'-oligoadenylate synthetase like increases expression EXP Fenofibrate results in increased expression of OASL mRNA CTD PMID:25572481 NCBI chr12:121,017,761...121,039,246
Ensembl chr12:121,017,763...121,039,246
JBrowse link
G OPA1 OPA1 mitochondrial dynamin like GTPase multiple interactions EXP Fenofibrate inhibits the reaction [[Fructose co-treated with Palmitic Acid] results in decreased expression of OPA1 protein] CTD PMID:32730863 NCBI chr 3:193,593,208...193,697,811
Ensembl chr 3:193,593,144...193,697,811
JBrowse link
G OR7E14P olfactory receptor family 7 subfamily E member 14 pseudogene increases expression EXP Fenofibrate results in increased expression of OR7E14P mRNA CTD PMID:25572481 NCBI chr11:17,051,886...17,053,044
Ensembl chr11:17,052,025...17,053,024
JBrowse link
G ORAI3 ORAI calcium release-activated calcium modulator 3 decreases expression EXP Fenofibrate results in decreased expression of ORAI3 mRNA CTD PMID:25596134 NCBI chr16:30,949,068...30,954,938
Ensembl chr16:30,949,068...30,956,461
JBrowse link
G ORM2 orosomucoid 2 decreases expression ISO Fenofibrate results in decreased expression of ORM2 mRNA CTD PMID:11798191 NCBI chr 9:114,329,869...114,333,251
Ensembl chr 9:114,329,869...114,333,251
JBrowse link
G OSGIN1 oxidative stress induced growth inhibitor 1 decreases expression ISO Fenofibrate results in decreased expression of OSGIN1 mRNA CTD PMID:25596134 NCBI chr16:83,953,240...83,966,332
Ensembl chr16:83,931,311...83,966,332
JBrowse link
G P4HA1 prolyl 4-hydroxylase subunit alpha 1 affects expression ISO Fenofibrate affects the expression of P4HA1 mRNA CTD PMID:25596134 NCBI chr10:73,007,217...73,096,866
Ensembl chr10:73,007,217...73,096,974
JBrowse link
G P4HB prolyl 4-hydroxylase subunit beta affects expression ISO Fenofibrate affects the expression of P4HB mRNA CTD PMID:20801182 NCBI chr17:81,843,166...81,860,535
Ensembl chr17:81,843,159...81,860,856
JBrowse link
G PANK1 pantothenate kinase 1 increases expression ISO
EXP
Fenofibrate results in increased expression of PANK1 mRNA CTD PMID:16707586 PMID:25572481 PMID:25596134 NCBI chr10:89,579,495...89,645,242
Ensembl chr10:89,579,497...89,645,242
JBrowse link
G PBK PDZ binding kinase increases expression ISO Fenofibrate results in increased expression of PBK mRNA CTD PMID:32741897 NCBI chr 8:27,809,624...27,837,817
Ensembl chr 8:27,809,624...27,838,082
JBrowse link
G PCK1 phosphoenolpyruvate carboxykinase 1 increases expression EXP Fenofibrate results in increased expression of PCK1 mRNA CTD PMID:25572481 NCBI chr20:57,561,110...57,568,121
Ensembl chr20:57,561,080...57,568,121
JBrowse link
G PCK2 phosphoenolpyruvate carboxykinase 2, mitochondrial increases expression EXP Fenofibrate results in increased expression of PCK2 mRNA CTD PMID:16569247 PMID:24752549 NCBI chr14:24,094,171...24,104,125
Ensembl chr14:24,094,053...24,110,598
JBrowse link
G PCNA proliferating cell nuclear antigen multiple interactions
increases expression
ISO
EXP
[Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of PCNA protein
Fenofibrate results in increased expression of PCNA protein
ESR1 protein inhibits the reaction [Fenofibrate results in increased expression of PCNA protein]; Estradiol inhibits the reaction [Fenofibrate results in increased expression of PCNA protein]
CTD PMID:18978307 PMID:29134746 NCBI chr20:5,114,953...5,126,622
Ensembl chr20:5,114,953...5,126,626
JBrowse link
G PCSK9 proprotein convertase subtilisin/kexin type 9 increases expression EXP Fenofibrate results in increased expression of PCSK9 protein CTD PMID:21411093 NCBI chr 1:55,039,548...55,064,852
Ensembl chr 1:55,039,445...55,064,852
JBrowse link
G PDIA5 protein disulfide isomerase family A member 5 decreases expression ISO Fenofibrate results in decreased expression of PDIA5 mRNA CTD PMID:25596134 NCBI chr 3:123,067,025...123,162,104
Ensembl chr 3:123,067,025...123,225,227
JBrowse link
G PDK1 pyruvate dehydrogenase kinase 1 decreases expression ISO Fenofibrate results in decreased expression of PDK1 mRNA CTD PMID:25596134 NCBI chr 2:172,555,373...172,724,312
Ensembl chr 2:172,555,373...172,608,669
JBrowse link
G PDK4 pyruvate dehydrogenase kinase 4 increases expression ISO
EXP
Fenofibrate results in increased expression of PDK4 mRNA CTD PMID:17118139 PMID:19395589 PMID:25572481 PMID:25596134 PMID:27665778 More... NCBI chr 7:95,583,499...95,596,516
Ensembl chr 7:95,583,499...95,596,516
JBrowse link
G PDLIM1 PDZ and LIM domain 1 decreases expression ISO Fenofibrate results in decreased expression of PDLIM1 mRNA CTD PMID:25596134 NCBI chr10:95,237,572...95,291,003
Ensembl chr10:95,237,572...95,291,012
JBrowse link
G PDRG1 p53 and DNA damage regulated 1 multiple interactions
decreases expression
ISO PPARA protein affects the reaction [Fenofibrate results in decreased expression of PDRG1 mRNA] CTD PMID:21318169 NCBI chr20:31,944,337...31,952,046
Ensembl chr20:31,944,337...31,952,046
JBrowse link
G PEMT phosphatidylethanolamine N-methyltransferase increases expression EXP Fenofibrate results in increased expression of PEMT mRNA CTD PMID:25572481 NCBI chr17:17,505,563...17,592,142
Ensembl chr17:17,505,563...17,591,708
JBrowse link
G PEX11A peroxisomal biogenesis factor 11 alpha affects expression
increases expression
ISO
EXP
Fenofibrate affects the expression of PEX11A mRNA
Fenofibrate results in increased expression of PEX11A mRNA
CTD PMID:20801182 PMID:25572481 PMID:27665778 PMID:32741897 NCBI chr15:89,681,535...89,690,754
Ensembl chr15:89,677,764...89,690,783
JBrowse link
G PGM1 phosphoglucomutase 1 increases expression EXP Fenofibrate results in increased expression of PGM1 mRNA CTD PMID:24752549 NCBI chr 1:63,593,411...63,660,245
Ensembl chr 1:63,593,411...63,660,245
JBrowse link
G PHGDH phosphoglycerate dehydrogenase increases expression ISO
EXP
Fenofibrate results in increased expression of PHGDH mRNA CTD PMID:25596134 NCBI chr 1:119,711,934...119,744,215
Ensembl chr 1:119,648,411...119,744,218
JBrowse link
G PHLDA1 pleckstrin homology like domain family A member 1 decreases expression ISO Fenofibrate results in decreased expression of PHLDA1 mRNA CTD PMID:11798191 NCBI chr12:76,025,447...76,031,776
Ensembl chr12:76,025,447...76,031,776
JBrowse link
G PHLDA3 pleckstrin homology like domain family A member 3 affects expression ISO Fenofibrate affects the expression of PHLDA3 mRNA CTD PMID:25596134 NCBI chr 1:201,464,278...201,469,188
Ensembl chr 1:201,464,278...201,469,237
JBrowse link
G PIK3C2G phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma decreases expression ISO Fenofibrate results in decreased expression of PIK3C2G mRNA CTD PMID:16707586 NCBI chr12:18,242,961...18,726,817
Ensembl chr12:18,242,961...18,648,416
JBrowse link
G PIR pirin decreases expression ISO Fenofibrate results in decreased expression of PIR mRNA CTD PMID:25596134 NCBI chr  X:15,384,799...15,493,333
Ensembl chr  X:15,384,799...15,493,564
JBrowse link
G PJA2 praja ring finger ubiquitin ligase 2 increases expression
multiple interactions
ISO Fenofibrate results in increased expression of PJA2 mRNA
PPARA protein affects the reaction [Fenofibrate results in increased expression of PJA2 mRNA]
CTD PMID:21318169 NCBI chr 5:109,334,722...109,409,974
Ensembl chr 5:109,334,713...109,409,974
JBrowse link
G PKIB cAMP-dependent protein kinase inhibitor beta increases expression EXP Fenofibrate results in increased expression of PKIB mRNA CTD PMID:25572481 NCBI chr 6:122,471,921...122,726,373
Ensembl chr 6:122,471,917...122,726,373
JBrowse link
G PKLR pyruvate kinase L/R decreases expression EXP Fenofibrate results in decreased expression of PKLR mRNA CTD PMID:25572481 NCBI chr 1:155,289,293...155,308,654
Ensembl chr 1:155,289,293...155,301,438
JBrowse link
G PLA1A phospholipase A1 member A increases expression EXP Fenofibrate results in increased expression of PLA1A mRNA CTD PMID:25572481 NCBI chr 3:119,597,885...119,629,811
Ensembl chr 3:119,597,875...119,629,811
JBrowse link
G PLA2G7 phospholipase A2 group VII decreases activity
multiple interactions
EXP Fenofibrate results in decreased activity of PLA2G7 protein
[orlistat co-treated with Fenofibrate] results in decreased activity of PLA2G7 protein
CTD PMID:16911813 NCBI chr 6:46,704,201...46,735,721
Ensembl chr 6:46,704,201...46,735,693
JBrowse link
G PLCXD3 phosphatidylinositol specific phospholipase C X domain containing 3 decreases expression EXP Fenofibrate results in decreased expression of PLCXD3 mRNA CTD PMID:25572481 NCBI chr 5:41,306,952...41,510,601
Ensembl chr 5:41,306,952...41,510,601
JBrowse link
G PLIN1 perilipin 1 increases expression EXP Fenofibrate results in increased expression of PLIN1 mRNA CTD PMID:25572481 NCBI chr15:89,664,367...89,679,367
Ensembl chr15:89,664,367...89,679,427
JBrowse link
G PLIN2 perilipin 2 increases expression
multiple interactions
EXP
ISO
Fenofibrate results in increased expression of PLIN2 mRNA
Fenofibrate promotes the reaction [Oleic Acid results in increased expression of PLIN2 mRNA]
CTD PMID:24534255 PMID:25572481 PMID:25596134 PMID:27665778 NCBI chr 9:19,108,388...19,127,492
Ensembl chr 9:19,108,375...19,149,290
JBrowse link
G PLIN4 perilipin 4 increases expression EXP Fenofibrate results in increased expression of PLIN4 mRNA CTD PMID:25572481 NCBI chr19:4,502,192...4,518,486
Ensembl chr19:4,502,192...4,518,486
JBrowse link
G PLIN5 perilipin 5 increases expression ISO Fenofibrate results in increased expression of PLIN5 mRNA CTD PMID:32741897 NCBI chr19:4,522,531...4,535,224
Ensembl chr19:4,522,531...4,535,224
JBrowse link
G PLTP phospholipid transfer protein increases expression ISO Fenofibrate results in increased expression of PLTP mRNA CTD PMID:11798191 NCBI chr20:45,898,620...45,912,155
Ensembl chr20:45,898,621...45,912,155
JBrowse link
G PMEPA1 prostate transmembrane protein, androgen induced 1 decreases expression ISO Fenofibrate results in decreased expression of PMEPA1 mRNA CTD PMID:25596134 NCBI chr20:57,648,396...57,711,472
Ensembl chr20:57,648,392...57,711,536
JBrowse link
G PML PML nuclear body scaffold multiple interactions EXP Fenofibrate promotes the reaction [Arsenic Trioxide results in decreased expression of PML protein mutant form] CTD PMID:32929351 NCBI chr15:73,994,716...74,047,827
Ensembl chr15:73,994,673...74,047,827
JBrowse link
G PODXL podocalyxin like decreases expression EXP
ISO
Fenofibrate results in decreased expression of PODXL mRNA CTD PMID:25596134 NCBI chr 7:131,500,271...131,556,628
Ensembl chr 7:131,500,262...131,558,217
JBrowse link
G PON1 paraoxonase 1 increases expression EXP Fenofibrate results in increased expression of PON1 protein CTD PMID:16123850 NCBI chr 7:95,297,676...95,324,532
Ensembl chr 7:95,297,676...95,324,532
JBrowse link
G POR cytochrome p450 oxidoreductase increases expression ISO
EXP
Fenofibrate results in increased expression of POR mRNA CTD PMID:16707586 PMID:25572481 NCBI chr 7:75,915,155...75,986,855
Ensembl chr 7:75,899,200...75,986,855
JBrowse link
G PPAN peter pan homolog affects expression ISO Fenofibrate affects the expression of PPAN mRNA CTD PMID:25596134 NCBI chr19:10,106,223...10,112,012
Ensembl chr19:10,106,362...10,112,012
JBrowse link
G PPARA peroxisome proliferator activated receptor alpha decreases expression
multiple interactions
decreases response to substance
increases activity
increases response to substance
increases expression
affects response to substance
EXP
ISO
Fenofibrate results in decreased expression of PPARA mRNA
fenofibrate co-treated with fructose diet decreases expression of ppara mRNA in liver
PPARA gene mutant form results in decreased susceptibility to Fenofibrate
Fenofibrate results in increased activity of PPARA protein
PPARA protein results in increased susceptibility to Fenofibrate
[Fenofibrate co-treated with Fatty Acids, Nonesterified] results in increased expression of PPARA mRNA; ESR1 protein inhibits the reaction [Estradiol inhibits the reaction [Fenofibrate inhibits the reaction [ESR1 protein binds to PPARA protein]]]; ESR1 protein inhibits the reaction [Fenofibrate inhibits the reaction [ESR1 protein binds to PPARA protein]]; Estradiol inhibits the reaction [ESR1 protein inhibits the reaction [Fenofibrate inhibits the reaction [ESR1 protein binds to PPARA protein]]]; Estradiol inhibits the reaction [Fenofibrate inhibits the reaction [ESR1 protein binds to PPARA protein]]; Fenofibrate binds to and results in increased activity of PPARA protein; Fenofibrate inhibits the reaction [ESR1 protein binds to PPARA protein]; Fenofibrate inhibits the reaction [Fatty Acids, Nonesterified results in decreased expression of PPARA mRNA]; Fenofibrate inhibits the reaction [Fatty Acids, Nonesterified results in decreased expression of PPARA protein]; NR1H3 protein affects the reaction [Fenofibrate results in increased expression of PPARA mRNA]; PPARA protein inhibits the reaction [Fenofibrate results in decreased expression of APOA1 mRNA]; PPARA protein promotes the reaction [Fenofibrate results in increased expression of ACOX1 protein]; PPARA protein promotes the reaction [Fenofibrate results in increased expression of ACSL1 protein]; PPARA protein promotes the reaction [Fenofibrate results in increased expression of LPL protein]; PPARA protein promotes the reaction [Fenofibrate results in increased expression of SLC27A4 protein]; PPARA protein promotes the reaction [Fenofibrate results in increased expression of UCP2 protein]
[Fenofibrate binds to and results in increased activity of PPARA protein] which affects the abundance of Fatty Acids, Nonesterified; [Fenofibrate binds to and results in increased activity of PPARA protein] which affects the abundance of Triglycerides; [Fenofibrate results in increased activity of PPARA protein] which results in decreased abundance of Adenosine Triphosphate; [Fenofibrate results in increased activity of PPARA protein] which results in increased expression of TRIB3 mRNA; [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of ASB6 mRNA; [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of BRCC3 mRNA; [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of DNAJC14 mRNA; [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of DNAJC19 mRNA; [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of DNAJC2 mRNA; [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of FKBP15 mRNA; [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of HECTD1 mRNA; [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of HSPB8 mRNA; [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of MAP1LC3A mRNA; [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of MGRN1 mRNA; [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of PRKAB2 mRNA; [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of SEC63 mRNA; [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of SMPD3 mRNA; [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of TOPORS mRNA; [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of UBR2 mRNA; Fenofibrate binds to and results in increased activity of PPARA protein; Fenofibrate inhibits the reaction [Zoledronic Acid results in decreased expression of PPARA mRNA]; Fenofibrate promotes the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; Fenofibrate results in increased expression of and results in increased activity of PPARA protein; Lipopolysaccharides inhibits the reaction [Fenofibrate results in increased expression of PPARA mRNA]; NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of PPARA mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of PPARA mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACACA mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACACB mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACLY mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACOX1 mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACOX1 protein]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACSL1 mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACSL1 protein]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of CYP4A10 mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of CYP4A14 mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ELOVL6 mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of FASN mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of LPL mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of LPL protein]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ME1 mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of NR1H3 mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of SCD1 mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of SCD2 mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of SLC27A4 mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of SLC27A4 protein]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of UCP2 mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of UCP2 protein]; PPARA promotes the reaction [Fenofibrate results in decreased expression of FGA mRNA]; PPARA protein affects the reaction [Fenofibrate affects the expression of BRAP mRNA]; PPARA protein affects the reaction [Fenofibrate promotes the reaction [APOA1 protein results in increased secretion of Lipids]]; PPARA protein affects the reaction [Fenofibrate results in decreased expression of ANAPC11 mRNA]; PPARA protein affects the reaction [Fenofibrate results in decreased expression of CISH mRNA]; PPARA protein affects the reaction [Fenofibrate results in decreased expression of CYLD mRNA]; PPARA protein affects the reaction [Fenofibrate results in decreased expression of DNAJB4 mRNA]; PPARA protein affects the reaction [Fenofibrate results in decreased expression of HSPA13 mRNA]; PPARA protein affects the reaction [Fenofibrate results in decreased expression of ITCH mRNA]; PPARA protein affects the reaction [Fenofibrate results in decreased expression of LNX1 mRNA]; PPARA protein affects the reaction [Fenofibrate results in decreased expression of LRSAM1 mRNA]; PPARA protein affects the reaction [Fenofibrate results in decreased expression of PDRG1 mRNA]; PPARA protein affects the reaction [Fenofibrate results in decreased expression of PPP3CA mRNA]; PPARA protein affects the reaction [Fenofibrate results in decreased expression of PRKAB1 mRNA]; PPARA protein affects the reaction [Fenofibrate results in decreased expression of RBJ mRNA]; PPARA protein affects the reaction [Fenofibrate results in decreased expression of RNF144B mRNA]; PPARA protein affects the reaction [Fenofibrate results in decreased expression of UBE2R2 mRNA]; PPARA protein affects the reaction [Fenofibrate results in decreased expression of URM1 mRNA]; PPARA protein affects the reaction [Fenofibrate results in decreased expression of USP36 mRNA]; PPARA protein affects the reaction [Fenofibrate results in decreased expression of WSB1 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of ACADM mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of ARIH1 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of ATE1 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of ATG12 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of ATG7 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of CANX mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of CBLB mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of CNOT4 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of DNAJA2 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of DNAJB6 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of DNAJC3 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of DNAJC5 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of ENC1 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of FBXO3 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of FBXO30 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of FBXO32 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of FOXO1 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of GRPEL2 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of HSP90AA1 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of HSP90AB1 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of HSPA4L mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of HSPA8 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of HSPA9 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of HSPB1 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of HSPH1 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of NEDD4 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of PJA2 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of PPP1R15B mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of PSMB2 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of PSMC6 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of PSMD4 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of RABGEF1 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of RNF14 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of SENP2 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of SOCS6 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of SPOP mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of TOR1B mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of TOR3A mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of TRIM63 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of TRIP12 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of UBE2Q2 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of UBE3A mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of URI1 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of USP1 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of USP10 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of USP22 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of USP38 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of USP7 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of USP9X mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of USPL1 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of VCPIP1 mRNA]
Fenofibrate results in increased expression of PPARA mRNA; Fenofibrate results in increased expression of PPARA protein
PPARA protein results in increased susceptibility to Fenofibrate; PPARA results in increased susceptibility to Fenofibrate
[Fenofibrate binds to and results in increased activity of PPARA protein] which results in increased expression of UCP2 mRNA; EDN1 protein promotes the reaction [Fenofibrate promotes the reaction [NFATC4 protein binds to PPARA protein]]; Fenofibrate binds to and results in increased activity of PPARA protein; Fenofibrate inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Dietary Carbohydrates] results in increased expression of PPARA protein]; Fenofibrate inhibits the reaction [Fructose results in decreased expression of and results in decreased activity of PPARA protein]; Fenofibrate inhibits the reaction [Pyrazinamide results in decreased expression of PPARA mRNA]; Fenofibrate inhibits the reaction [tert-Butylhydroperoxide results in decreased expression of PPARA mRNA]; Fenofibrate inhibits the reaction [tert-Butylhydroperoxide results in decreased expression of PPARA protein]; Fenofibrate promotes the reaction [NFATC4 protein binds to PPARA protein]; Fenofibrate promotes the reaction [PPARA protein results in increased expression of MLYCD mRNA]; PPARA mutant form inhibits the reaction [Fenofibrate inhibits the reaction [EDN1 protein promotes the reaction [NFATC4 protein binds to GATA4 protein]]]; PPARA mutant form inhibits the reaction [Fenofibrate inhibits the reaction [EDN1 protein results in increased expression of NPPB mRNA]]
CTD
RGD
PMID:7983038 PMID:10216095 PMID:11341955 PMID:11798191 PMID:11934685 More... RGD:628329 NCBI chr22:46,150,526...46,243,756
Ensembl chr22:46,150,521...46,243,755
JBrowse link
G PPARD peroxisome proliferator activated receptor delta increases expression
multiple interactions
EXP
ISO
Fenofibrate results in increased expression of PPARD mRNA
Fenofibrate inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Dietary Carbohydrates] results in increased expression of PPARD protein]
CTD PMID:18338635 PMID:19201410 NCBI chr 6:35,342,558...35,428,178
Ensembl chr 6:35,342,558...35,428,191
JBrowse link
G PPARG peroxisome proliferator activated receptor gamma increases expression
affects activity
multiple interactions
EXP
ISO
Fenofibrate results in increased expression of PPARG mRNA
Fenofibrate affects the activity of PPARG protein
[Oleic Acid co-treated with Fenofibrate] results in increased expression of PPARG mRNA
CTD PMID:19201410 PMID:24534255 PMID:25596134 PMID:28034800 NCBI chr 3:12,287,368...12,434,344
Ensembl chr 3:12,287,368...12,434,356
JBrowse link
G PPARGC1A PPARG coactivator 1 alpha multiple interactions ISO
EXP
Fenofibrate inhibits the reaction [zoledronic acid results in decreased expression of PPARGC1A mRNA]
Fenofibrate inhibits the reaction [[Fructose co-treated with Palmitic Acid] results in decreased expression of PPARGC1A protein]
CTD PMID:28871336 PMID:32730863 NCBI chr 4:23,792,021...24,472,905
Ensembl chr 4:23,755,041...23,904,089
JBrowse link
G PPCS phosphopantothenoylcysteine synthetase increases expression ISO Fenofibrate results in increased expression of PPCS mRNA CTD PMID:27665778 NCBI chr 1:42,456,341...42,473,417
Ensembl chr 1:42,456,117...42,473,385
JBrowse link
G PPM1D protein phosphatase, Mg2+/Mn2+ dependent 1D decreases expression ISO Fenofibrate results in decreased expression of PPM1D mRNA CTD PMID:25596134 NCBI chr17:60,600,193...60,666,280
Ensembl chr17:60,600,193...60,666,280
JBrowse link
G PPP1R15A protein phosphatase 1 regulatory subunit 15A increases expression
decreases expression
EXP
ISO
Fenofibrate results in increased expression of PPP1R15A mRNA
Fenofibrate results in decreased expression of PPP1R15A mRNA
CTD PMID:25596134 NCBI chr19:48,872,421...48,876,058
Ensembl chr19:48,872,212...48,876,059
JBrowse link
G PPP1R15B protein phosphatase 1 regulatory subunit 15B increases expression
multiple interactions
ISO Fenofibrate results in increased expression of PPP1R15B mRNA
PPARA protein affects the reaction [Fenofibrate results in increased expression of PPP1R15B mRNA]
CTD PMID:21318169 NCBI chr 1:204,395,826...204,411,817
Ensembl chr 1:204,396,492...204,411,887
JBrowse link
G PPP3CA protein phosphatase 3 catalytic subunit alpha multiple interactions
decreases expression
ISO PPARA protein affects the reaction [Fenofibrate results in decreased expression of PPP3CA mRNA] CTD PMID:21318169 NCBI chr 4:101,023,418...101,347,526
Ensembl chr 4:101,023,409...101,348,278
JBrowse link
G PRKAA1 protein kinase AMP-activated catalytic subunit alpha 1 multiple interactions
decreases response to substance
EXP PRKAA1 protein affects the reaction [Fenofibrate results in decreased susceptibility to ALB protein modified form]; PRKAA1 protein affects the reaction [Fenofibrate results in increased abundance of Nitric Oxide]; PRKAA1 protein affects the reaction [Fenofibrate results in increased activity of NOS3 protein]
PRKAA1 gene mutant form results in decreased susceptibility to Fenofibrate
CTD PMID:20580385 PMID:25545733 NCBI chr 5:40,759,389...40,798,374
Ensembl chr 5:40,759,389...40,798,374
JBrowse link
G PRKAB1 protein kinase AMP-activated non-catalytic subunit beta 1 decreases expression
increases phosphorylation
multiple interactions
ISO
EXP
Fenofibrate results in decreased expression of PRKAB1 mRNA
Fenofibrate results in increased phosphorylation of PRKAB1 protein
PPARA protein affects the reaction [Fenofibrate results in decreased expression of PRKAB1 mRNA]
CTD PMID:21318169 PMID:25545733 NCBI chr12:119,667,952...119,681,619
Ensembl chr12:119,667,864...119,681,624
JBrowse link
G PRKAB2 protein kinase AMP-activated non-catalytic subunit beta 2 increases expression
multiple interactions
ISO Fenofibrate results in increased expression of PRKAB2 mRNA
[PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of PRKAB2 mRNA
CTD PMID:21318169 NCBI chr 1:147,155,106...147,172,470
Ensembl chr 1:147,155,106...147,172,550
JBrowse link
G PRKAG1 protein kinase AMP-activated non-catalytic subunit gamma 1 increases expression EXP Fenofibrate results in increased expression of PRKAG1 protein CTD PMID:25545733 NCBI chr12:49,002,274...49,018,776
Ensembl chr12:49,002,274...49,018,807
JBrowse link
G PRODH proline dehydrogenase 1 decreases expression EXP Fenofibrate results in decreased expression of PRODH mRNA CTD PMID:25572481 NCBI chr22:18,912,781...18,936,553
Ensembl chr22:18,912,777...18,936,553
JBrowse link
G PRRG4 proline rich and Gla domain 4 increases expression ISO Fenofibrate results in increased expression of PRRG4 mRNA CTD PMID:32741897 NCBI chr11:32,829,789...32,858,120
Ensembl chr11:32,829,927...32,858,120
JBrowse link
G PSEN1 presenilin 1 multiple interactions EXP Fenofibrate affects the reaction [PSEN1 protein affects the cleavage of APP protein] CTD PMID:17962197 NCBI chr14:73,136,417...73,223,691
Ensembl chr14:73,136,418...73,223,691
JBrowse link
G PSMB2 proteasome 20S subunit beta 2 increases expression
multiple interactions
ISO Fenofibrate results in increased expression of PSMB2 mRNA
PPARA protein affects the reaction [Fenofibrate results in increased expression of PSMB2 mRNA]
CTD PMID:21318169 NCBI chr 1:35,599,541...35,641,526
Ensembl chr 1:35,599,541...35,641,526
JBrowse link
G PSMC6 proteasome 26S subunit, ATPase 6 increases expression
multiple interactions
ISO Fenofibrate results in increased expression of PSMC6 mRNA
PPARA protein affects the reaction [Fenofibrate results in increased expression of PSMC6 mRNA]
CTD PMID:21318169 NCBI chr14:52,707,200...52,728,590
Ensembl chr14:52,707,178...52,728,590
JBrowse link
G PSMD4 proteasome 26S subunit ubiquitin receptor, non-ATPase 4 increases expression
multiple interactions
ISO Fenofibrate results in increased expression of PSMD4 mRNA
PPARA protein affects the reaction [Fenofibrate results in increased expression of PSMD4 mRNA]
CTD PMID:21318169 NCBI chr 1:151,254,734...151,267,479
Ensembl chr 1:151,254,709...151,267,479
JBrowse link
G PTGS1 prostaglandin-endoperoxide synthase 1 multiple interactions ISO [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of PTGS1 mRNA CTD PMID:18253720 NCBI chr 9:122,370,533...122,395,703
Ensembl chr 9:122,370,530...122,395,703
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO Fenofibrate inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA] CTD PMID:21300114 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922
JBrowse link
G PTPRF protein tyrosine phosphatase receptor type F affects expression ISO Fenofibrate affects the expression of PTPRF mRNA CTD PMID:20801182 NCBI chr 1:43,522,051...43,623,666
Ensembl chr 1:43,525,187...43,623,666
JBrowse link
G PTPRQ protein tyrosine phosphatase receptor type Q decreases expression EXP Fenofibrate results in decreased expression of PTPRQ mRNA CTD PMID:25572481 NCBI chr12:80,444,235...80,680,273
Ensembl chr12:80,402,178...80,680,273
JBrowse link
G PYGL glycogen phosphorylase L increases expression ISO Fenofibrate results in increased expression of PYGL mRNA CTD PMID:25596134 NCBI chr14:50,905,217...50,944,483
Ensembl chr14:50,857,891...50,944,483
JBrowse link
G QPCT glutaminyl-peptide cyclotransferase increases expression ISO Fenofibrate results in increased expression of QPCT mRNA CTD PMID:27665778 PMID:32741897 NCBI chr 2:37,344,630...37,373,322
Ensembl chr 2:37,342,827...37,373,322
JBrowse link
G RAB30 RAB30, member RAS oncogene family increases expression ISO Fenofibrate results in increased expression of RAB30 mRNA CTD PMID:32741897 NCBI chr11:82,973,133...83,071,897
Ensembl chr11:82,973,133...83,071,923
JBrowse link
G RAB31 RAB31, member RAS oncogene family decreases expression EXP Fenofibrate results in decreased expression of RAB31 mRNA CTD PMID:25596134 NCBI chr18:9,708,301...9,862,551
Ensembl chr18:9,708,275...9,862,551
JBrowse link
G RABGEF1 RAB guanine nucleotide exchange factor 1 increases expression
multiple interactions
ISO Fenofibrate results in increased expression of RABGEF1 mRNA
PPARA protein affects the reaction [Fenofibrate results in increased expression of RABGEF1 mRNA]
CTD PMID:21318169 NCBI chr 7:66,654,567...66,811,464
Ensembl chr 7:66,682,164...66,811,464
JBrowse link
G RAD50 RAD50 double strand break repair protein multiple interactions ISO [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of RAD50 mRNA CTD PMID:18253720 NCBI chr 5:132,556,977...132,646,349
Ensembl chr 5:132,556,019...132,646,349
JBrowse link
G RAD51B RAD51 paralog B increases expression ISO Fenofibrate results in increased expression of RAD51B mRNA CTD PMID:11798191 NCBI chr14:67,819,779...68,683,096
Ensembl chr14:67,819,779...68,730,218
JBrowse link
G RAET1E retinoic acid early transcript 1E increases expression ISO Fenofibrate results in increased expression of RAET1E mRNA CTD PMID:11798191 NCBI chr 6:149,883,179...149,898,113
Ensembl chr 6:149,883,179...149,898,113
JBrowse link
G RAMP2 receptor activity modifying protein 2 decreases expression ISO Fenofibrate results in decreased expression of RAMP2 mRNA CTD PMID:11798191 NCBI chr17:42,761,227...42,763,041
Ensembl chr17:42,758,447...42,763,041
JBrowse link
G RARA retinoic acid receptor alpha multiple interactions
decreases expression
ISO
EXP
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of RARA mRNA
Fenofibrate results in decreased expression of RARA mRNA
CTD PMID:18253720 PMID:25596134 NCBI chr17:40,309,180...40,357,643
Ensembl chr17:40,309,180...40,357,643
JBrowse link
G RARB retinoic acid receptor beta multiple interactions ISO [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of RARB mRNA CTD PMID:18253720 NCBI chr 3:24,829,321...25,597,932
Ensembl chr 3:24,687,887...25,597,932
JBrowse link
G RBP2 retinol binding protein 2 increases expression ISO Fenofibrate results in increased expression of RBP2 mRNA CTD PMID:32741897 NCBI chr 3:139,452,884...139,476,516
Ensembl chr 3:139,452,884...139,480,747
JBrowse link
G RBX1 ring-box 1 decreases expression ISO Fenofibrate results in decreased expression of RBX1 mRNA CTD PMID:21318169 NCBI chr22:40,951,378...40,973,309
Ensembl chr22:40,951,347...40,973,309
JBrowse link
G RDH16 retinol dehydrogenase 16 increases expression ISO Fenofibrate results in increased expression of RDH16 mRNA CTD PMID:11798191 NCBI chr12:56,951,431...56,957,608
Ensembl chr12:56,951,431...56,959,374
JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit multiple interactions EXP
ISO
Fenofibrate affects the localization of and results in decreased activity of RELA protein; Fenofibrate inhibits the reaction [ALB protein modified form results in increased expression of RELA protein]; Fenofibrate inhibits the reaction [Glucose results in increased expression of RELA protein]; Fenofibrate results in decreased localization of and results in decreased activity of RELA protein
[Fenofibrate co-treated with Sodium Glutamate] results in increased expression of RELA protein; Fenofibrate inhibits the reaction [Dietary Fats results in increased expression of RELA protein]; Fenofibrate inhibits the reaction [Doxorubicin results in increased expression of RELA protein]; Fenofibrate promotes the reaction [Pioglitazone inhibits the reaction [Doxorubicin results in increased expression of RELA protein]]; Pioglitazone promotes the reaction [Fenofibrate inhibits the reaction [Doxorubicin results in increased expression of RELA protein]]
CTD PMID:16600694 PMID:20520642 PMID:20580385 PMID:21999347 PMID:25545733 More... NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090
JBrowse link
G RETN resistin multiple interactions EXP Fenofibrate inhibits the reaction [Arsenic Trioxide results in increased expression of and results in increased secretion of RETN protein] CTD PMID:32929351 NCBI chr19:7,669,049...7,670,455
Ensembl chr19:7,669,049...7,670,455
JBrowse link
G RETSAT retinol saturase increases expression ISO Fenofibrate results in increased expression of RETSAT mRNA CTD PMID:11798191 NCBI chr 2:85,341,955...85,354,528
Ensembl chr 2:85,341,955...85,354,531
JBrowse link
G RGS16 regulator of G protein signaling 16 increases expression ISO Fenofibrate results in increased expression of RGS16 mRNA CTD PMID:32741897 NCBI chr 1:182,598,623...182,604,389
Ensembl chr 1:182,598,623...182,604,389
JBrowse link
G RHOF ras homolog family member F, filopodia associated increases expression ISO Fenofibrate results in increased expression of RHOF mRNA CTD PMID:32741897 NCBI chr12:121,777,754...121,793,688
Ensembl chr12:121,777,754...121,803,403
JBrowse link
G RLF RLF zinc finger increases expression ISO Fenofibrate results in increased expression of RLF mRNA CTD PMID:25596134 NCBI chr 1:40,161,387...40,240,921
Ensembl chr 1:40,161,387...40,240,921
JBrowse link
G RND1 Rho family GTPase 1 decreases expression ISO Fenofibrate results in decreased expression of RND1 mRNA CTD PMID:25596134 NCBI chr12:48,857,145...48,865,870
Ensembl chr12:48,857,145...48,865,870
JBrowse link
G RND3 Rho family GTPase 3 decreases expression ISO Fenofibrate results in decreased expression of RND3 mRNA CTD PMID:25596134 NCBI chr 2:150,468,193...150,487,695
Ensembl chr 2:150,468,195...150,539,011
JBrowse link
G RNF125 ring finger protein 125 increases expression ISO Fenofibrate results in increased expression of RNF125 mRNA CTD PMID:21318169 NCBI chr18:32,018,825...32,088,144
Ensembl chr18:32,018,825...32,088,144
JBrowse link
G RNF14 ring finger protein 14 increases expression
multiple interactions
ISO Fenofibrate results in increased expression of RNF14 mRNA
PPARA protein affects the reaction [Fenofibrate results in increased expression of RNF14 mRNA]
CTD PMID:21318169 NCBI chr 5:141,949,337...141,990,292
Ensembl chr 5:141,958,328...141,990,292
JBrowse link
G RNF144B ring finger protein 144B decreases expression
multiple interactions
ISO Fenofibrate results in decreased expression of RNF144B mRNA
PPARA protein affects the reaction [Fenofibrate results in decreased expression of RNF144B mRNA]
CTD PMID:21318169 NCBI chr 6:18,387,350...18,468,870
Ensembl chr 6:18,387,350...18,468,870
JBrowse link
G RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase increases expression ISO Fenofibrate results in increased expression of RNF19A mRNA CTD PMID:21318169 NCBI chr 8:100,257,067...100,336,204
Ensembl chr 8:100,257,060...100,336,218
JBrowse link
G RO60 Ro60, Y RNA binding protein decreases expression EXP Fenofibrate results in decreased expression of RO60 mRNA CTD PMID:25596134 NCBI chr 1:193,059,612...193,091,777
Ensembl chr 1:193,059,454...193,091,777
JBrowse link
G RSRC2 arginine and serine rich coiled-coil 2 decreases expression ISO Fenofibrate results in decreased expression of RSRC2 mRNA CTD PMID:25596134 NCBI chr12:122,503,454...122,526,936
Ensembl chr12:122,503,454...122,527,000
JBrowse link
G RXRA retinoid X receptor alpha decreases expression
affects expression
EXP
ISO
Fenofibrate results in decreased expression of RXRA mRNA
Fenofibrate affects the expression of RXRA mRNA
CTD PMID:25596134 NCBI chr 9:134,326,455...134,440,585
Ensembl chr 9:134,317,098...134,440,585
JBrowse link
G S100A10 S100 calcium binding protein A10 increases expression ISO Fenofibrate results in increased expression of S100A10 mRNA CTD PMID:11798191 NCBI chr 1:151,982,915...151,993,859
Ensembl chr 1:151,982,915...151,993,859
JBrowse link
G SAA1 serum amyloid A1 decreases expression ISO Fenofibrate results in decreased expression of SAA1 mRNA CTD PMID:11798191 NCBI chr11:18,266,264...18,269,967
Ensembl chr11:18,266,260...18,269,977
JBrowse link
G SAA2 serum amyloid A2 decreases expression ISO Fenofibrate results in decreased expression of SAA2 mRNA CTD PMID:11798191 NCBI chr11:18,238,236...18,248,668
Ensembl chr11:18,239,223...18,248,668
JBrowse link
G SAA3P serum amyloid A3, pseudogene decreases expression ISO Fenofibrate results in decreased expression of SAA3 mRNA CTD PMID:11798191 NCBI chr11:18,112,472...18,116,132
Ensembl chr11:18,112,472...18,116,132
Ensembl chr11:18,112,472...18,116,132
JBrowse link
G SARS1 seryl-tRNA synthetase 1 increases expression ISO Fenofibrate results in increased expression of SARS1 mRNA CTD PMID:25596134 NCBI chr 1:109,213,893...109,238,182
Ensembl chr 1:109,213,918...109,238,182
JBrowse link
G SAT1 spermidine/spermine N1-acetyltransferase 1 increases expression ISO Fenofibrate results in increased expression of SAT1 mRNA CTD PMID:25596134 NCBI chr  X:23,783,173...23,786,210
Ensembl chr  X:23,783,173...23,786,210
JBrowse link
G SCAMP1 secretory carrier membrane protein 1 decreases expression ISO Fenofibrate results in decreased expression of SCAMP1 mRNA CTD PMID:25596134 NCBI chr 5:78,360,617...78,480,739
Ensembl chr 5:78,360,611...78,480,739
JBrowse link
G SCARB1 scavenger receptor class B member 1 multiple interactions
decreases activity
increases expression
EXP
ISO
[Aspirin co-treated with Fenofibrate] results in increased expression of SCARB1 protein
Fenofibrate results in decreased activity of SCARB1 protein
Fenofibrate inhibits the reaction [SCARB1 protein results in increased export of Cholesterol, HDL]; Fenofibrate inhibits the reaction [SCARB1 protein results in increased uptake of cholesteryl oleyl ether]
Fenofibrate results in increased expression of SCARB1 protein
CTD PMID:16816107 PMID:17533223 NCBI chr12:124,776,856...124,863,864
Ensembl chr12:124,776,856...124,882,668
JBrowse link
G SCD stearoyl-CoA desaturase multiple interactions
increases expression
affects expression
EXP
ISO
[Oleic Acid co-treated with Fenofibrate] results in increased expression of SCD1 mRNA
NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of SCD2 mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of SCD2 mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of SCD2 mRNA]
Fenofibrate results in increased expression of SCD mRNA; Fenofibrate results in increased expression of SCD2 mRNA
Fenofibrate affects the expression of SCD mRNA
CTD PMID:17118139 PMID:23063693 PMID:24534255 PMID:27665778 NCBI chr10:100,347,233...100,364,826
Ensembl chr10:100,347,233...100,364,826
JBrowse link
G SCLY selenocysteine lyase affects expression ISO Fenofibrate affects the expression of SCLY mRNA CTD PMID:20801182 NCBI chr 2:238,061,001...238,099,413
Ensembl chr 2:238,060,924...238,099,413
JBrowse link
G SDHB succinate dehydrogenase complex iron sulfur subunit B increases expression EXP Fenofibrate results in increased expression of SDHB protein CTD PMID:24752549 NCBI chr 1:17,018,722...17,054,032
Ensembl chr 1:17,018,664...17,054,151
JBrowse link
G SEC63 SEC63 homolog, protein translocation regulator increases expression
multiple interactions
ISO Fenofibrate results in increased expression of SEC63 mRNA
[PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of SEC63 mRNA
CTD PMID:21318169 NCBI chr 6:107,867,756...107,958,208
Ensembl chr 6:107,867,756...107,958,208
JBrowse link
G SELE selectin E multiple interactions EXP dorsomorphin inhibits the reaction [Fenofibrate inhibits the reaction [ALB protein modified form results in increased expression of SELE mRNA]]; Fenofibrate inhibits the reaction [ALB protein modified form results in increased expression of SELE mRNA] CTD PMID:20580385 NCBI chr 1:169,722,640...169,734,079
Ensembl chr 1:169,722,640...169,764,705
JBrowse link
G SEMA6B semaphorin 6B multiple interactions
decreases expression
EXP alitretinoin promotes the reaction [Fenofibrate results in decreased expression of SEMA6B mRNA]; alitretinoin promotes the reaction [Fenofibrate results in decreased expression of SEMA6B protein]
Fenofibrate results in decreased expression of SEMA6B mRNA; Fenofibrate results in decreased expression of SEMA6B protein
CTD PMID:16525649 NCBI chr19:4,542,593...4,559,684
Ensembl chr19:4,542,588...4,581,776
JBrowse link
G SENP2 SUMO specific peptidase 2 increases expression
multiple interactions
ISO Fenofibrate results in increased expression of SENP2 mRNA
PPARA protein affects the reaction [Fenofibrate results in increased expression of SENP2 mRNA]
CTD PMID:21318169 NCBI chr 3:185,586,295...185,633,551
Ensembl chr 3:185,582,496...185,633,551
JBrowse link
G SERPINA3 serpin family A member 3 affects expression ISO Fenofibrate affects the expression of SERPINA3N mRNA CTD PMID:20801182 NCBI chr14:94,612,391...94,624,053
Ensembl chr14:94,612,384...94,624,055
JBrowse link
G SERPINE1 serpin family E member 1 multiple interactions
affects expression
EXP
ISO
Fenofibrate inhibits the reaction [NR4A1 protein results in increased expression of SERPINE1 mRNA]; Fenofibrate inhibits the reaction [SMAD3 protein results in increased expression of SERPINE1 mRNA]; Fenofibrate inhibits the reaction [SMAD4 protein results in increased expression of SERPINE1 mRNA]; Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of SERPINE1 mRNA]; Fenofibrate inhibits the reaction [TNF protein results in increased expression of SERPINE1 mRNA]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [NR4A1 protein results in increased expression of SERPINE1 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [SMAD3 protein results in increased expression of SERPINE1 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [SMAD4 protein results in increased expression of SERPINE1 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of SERPINE1 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [TNF protein results in increased expression of SERPINE1 mRNA]]
[Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of SERPINE1 mRNA
Fenofibrate affects the expression of SERPINE1 mRNA
Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of SERPINE1 mRNA]; Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of SERPINE1 mRNA]; NR0B2 protein inhibits the reaction [Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of SERPINE1 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of SERPINE1 mRNA]]
CTD PMID:18253720 PMID:19593819 PMID:20801182 NCBI chr 7:101,127,104...101,139,247
Ensembl chr 7:101,127,104...101,139,247
JBrowse link
G SERTAD1 SERTA domain containing 1 decreases expression ISO Fenofibrate results in decreased expression of SERTAD1 mRNA CTD PMID:25596134 NCBI chr19:40,421,589...40,425,992
Ensembl chr19:40,421,589...40,425,992
JBrowse link
G SESN1 sestrin 1 decreases expression ISO Fenofibrate results in decreased expression of SESN1 mRNA CTD PMID:25596134 NCBI chr 6:108,984,309...109,094,846
Ensembl chr 6:108,984,309...109,094,846
JBrowse link
G SGK2 serum/glucocorticoid regulated kinase 2 increases expression EXP Fenofibrate results in increased expression of SGK2 mRNA CTD PMID:25572481 NCBI chr20:43,559,027...43,585,627
Ensembl chr20:43,558,968...43,588,237
JBrowse link
G SH3BGRL2 SH3 domain binding glutamate rich protein like 2 increases expression EXP Fenofibrate results in increased expression of SH3BGRL2 mRNA CTD PMID:25572481 NCBI chr 6:79,537,633...79,703,655
Ensembl chr 6:79,537,185...79,703,655
JBrowse link
G SH3TC1 SH3 domain and tetratricopeptide repeats 1 increases expression EXP Fenofibrate results in increased expression of SH3TC1 mRNA CTD PMID:25596134 NCBI chr 4:8,182,072...8,241,103
Ensembl chr 4:8,182,072...8,241,803
JBrowse link
G SIAH2 siah E3 ubiquitin protein ligase 2 affects expression ISO Fenofibrate affects the expression of SIAH2 mRNA CTD PMID:25596134 NCBI chr 3:150,741,125...150,763,169
Ensembl chr 3:150,741,125...150,763,477
JBrowse link
G SIK1 salt inducible kinase 1 increases expression
decreases expression
EXP
ISO
Fenofibrate results in increased expression of SIK1 mRNA
Fenofibrate results in decreased expression of SIK1 mRNA
CTD PMID:25596134 NCBI chr21:43,414,483...43,427,131
Ensembl chr21:43,414,483...43,427,131
JBrowse link
G SIRT1 sirtuin 1 multiple interactions
increases expression
EXP
ISO
dorsomorphin inhibits the reaction [Fenofibrate results in increased expression of SIRT1 protein]; Fenofibrate inhibits the reaction [[Fructose co-treated with Palmitic Acid] results in decreased expression of SIRT1 protein]; zinc protoporphyrin inhibits the reaction [Fenofibrate results in increased expression of SIRT1 protein] CTD PMID:32730863 PMID:34520103 NCBI chr10:67,884,656...67,918,390
Ensembl chr10:67,884,656...67,918,390
JBrowse link
G SIVA1 SIVA1 apoptosis inducing factor decreases expression ISO Fenofibrate results in decreased expression of SIVA1 mRNA CTD PMID:25596134 NCBI chr14:104,753,147...104,759,654
Ensembl chr14:104,753,147...104,768,494
JBrowse link
G SLC10A1 solute carrier family 10 member 1 decreases expression EXP
ISO
Fenofibrate results in decreased expression of SLC10A1 mRNA CTD PMID:25572481 PMID:27765674 NCBI chr14:69,775,416...69,797,241
Ensembl chr14:69,775,416...69,797,241
JBrowse link
G SLC16A13 solute carrier family 16 member 13 increases expression EXP Fenofibrate results in increased expression of SLC16A13 mRNA CTD PMID:25572481 NCBI chr17:7,036,015...7,040,117
Ensembl chr17:7,036,015...7,040,117
JBrowse link
G SLC16A6 solute carrier family 16 member 6 increases expression ISO Fenofibrate results in increased expression of SLC16A6 mRNA CTD PMID:25596134 NCBI chr17:68,267,026...68,291,479
Ensembl chr17:68,267,026...68,291,267
JBrowse link
G SLC1A7 solute carrier family 1 member 7 increases expression EXP Fenofibrate results in increased expression of SLC1A7 mRNA CTD PMID:25596134 NCBI chr 1:53,087,183...53,142,638
Ensembl chr 1:53,087,179...53,142,638
JBrowse link
G SLC22A5 solute carrier family 22 member 5 increases expression ISO Fenofibrate results in increased expression of SLC22A5 mRNA CTD PMID:27665778 PMID:32741897 NCBI chr 5:132,369,710...132,395,612
Ensembl chr 5:132,369,710...132,395,613
JBrowse link
G SLC25A20 solute carrier family 25 member 20 increases expression ISO
EXP
Fenofibrate results in increased expression of SLC25A20 mRNA CTD PMID:16707586 PMID:25572481 PMID:25596134 NCBI chr 3:48,856,926...48,898,882
Ensembl chr 3:48,856,926...48,898,904
JBrowse link
G SLC25A30 solute carrier family 25 member 30 increases expression ISO Fenofibrate results in increased expression of SLC25A30 mRNA CTD PMID:32741897 NCBI chr13:45,393,316...45,434,016
Ensembl chr13:45,393,316...45,418,455
JBrowse link
G SLC25A34 solute carrier family 25 member 34 increases expression EXP Fenofibrate results in increased expression of SLC25A34 mRNA CTD PMID:25572481 NCBI chr 1:15,736,258...15,741,392
Ensembl chr 1:15,736,258...15,741,392
JBrowse link
G SLC25A4 solute carrier family 25 member 4 decreases expression ISO Fenofibrate results in decreased expression of SLC25A4 protein CTD PMID:20118634 NCBI chr 4:185,143,266...185,150,382
Ensembl chr 4:185,143,266...185,150,382
JBrowse link
G SLC27A1 solute carrier family 27 member 1 increases expression ISO Fenofibrate results in increased expression of SLC27A1 mRNA CTD PMID:11798191 NCBI chr19:17,468,767...17,506,168
Ensembl chr19:17,468,769...17,506,168
JBrowse link
G SLC27A2 solute carrier family 27 member 2 increases expression ISO
EXP
Fenofibrate results in increased expression of SLC27A2 mRNA CTD PMID:17118139 PMID:25572481 PMID:27665778 PMID:32741897 PMID:32741898 NCBI chr15:50,182,196...50,236,385
Ensembl chr15:50,182,196...50,236,385
JBrowse link
G SLC27A4 solute carrier family 27 member 4 increases expression
multiple interactions
EXP
ISO
Fenofibrate results in increased expression of SLC27A4 mRNA; Fenofibrate results in increased expression of SLC27A4 protein
PPARA protein promotes the reaction [Fenofibrate results in increased expression of SLC27A4 protein]
PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of SLC27A4 mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of SLC27A4 protein]
CTD PMID:24752549 NCBI chr 9:128,340,527...128,361,470
Ensembl chr 9:128,340,527...128,361,470
JBrowse link
G SLC34A2 solute carrier family 34 member 2 increases expression ISO Fenofibrate results in increased expression of SLC34A2 mRNA CTD PMID:32741897 NCBI chr 4:25,655,851...25,678,748
Ensembl chr 4:25,648,011...25,678,748
JBrowse link
G SLC3A2 solute carrier family 3 member 2 increases expression EXP
ISO
Fenofibrate results in increased expression of SLC3A2 mRNA CTD PMID:25596134 NCBI chr11:62,856,109...62,888,860
Ensembl chr11:62,856,004...62,888,880
JBrowse link
G SLC6A9 solute carrier family 6 member 9 decreases expression
increases expression
ISO
EXP
Fenofibrate results in decreased expression of SLC6A9 mRNA
Fenofibrate results in increased expression of SLC6A9 mRNA
CTD PMID:25596134 NCBI chr 1:43,996,483...44,031,462
Ensembl chr 1:43,991,500...44,031,467
JBrowse link
G SLC7A1 solute carrier family 7 member 1 increases expression ISO
EXP
Fenofibrate results in increased expression of SLC7A1 mRNA CTD PMID:25596134 NCBI chr13:29,509,414...29,595,688
Ensembl chr13:29,509,414...29,595,688
JBrowse link
G SLC7A5 solute carrier family 7 member 5 increases expression EXP Fenofibrate results in increased expression of SLC7A5 mRNA CTD PMID:25596134 NCBI chr16:87,830,023...87,869,507
Ensembl chr16:87,830,016...87,869,507
JBrowse link
G SLCO2B1 solute carrier organic anion transporter family member 2B1 decreases expression EXP
ISO
Fenofibrate results in decreased expression of SLCO2B1 mRNA CTD PMID:25596134 NCBI chr11:75,151,107...75,206,549
Ensembl chr11:75,100,563...75,206,549
JBrowse link
G SMAD3 SMAD family member 3 multiple interactions EXP Fenofibrate inhibits the reaction [SMAD3 protein results in increased expression of SERPINE1 mRNA]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [SMAD3 protein results in increased expression of SERPINE1 mRNA]] CTD PMID:19593819 NCBI chr15:67,065,602...67,195,169
Ensembl chr15:67,063,763...67,195,173
JBrowse link
G SMAD4 SMAD family member 4 multiple interactions EXP Fenofibrate inhibits the reaction [SMAD4 protein results in increased expression of SERPINE1 mRNA]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [SMAD4 protein results in increased expression of SERPINE1 mRNA]] CTD PMID:19593819 NCBI chr18:51,030,213...51,085,042
Ensembl chr18:51,028,528...51,085,045
JBrowse link
G SMPD2 sphingomyelin phosphodiesterase 2 multiple interactions ISO Fenofibrate promotes the reaction [Dextran Sulfate results in decreased expression of SMPD2 mRNA] CTD PMID:25035112 NCBI chr 6:109,440,724...109,443,919
Ensembl chr 6:109,440,724...109,443,919
JBrowse link
G SMPD3 sphingomyelin phosphodiesterase 3 increases expression
multiple interactions
ISO Fenofibrate results in increased expression of SMPD3 mRNA
[PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of SMPD3 mRNA
CTD PMID:21318169 NCBI chr16:68,358,327...68,448,508
Ensembl chr16:68,358,327...68,448,508
JBrowse link
G SMPD4 sphingomyelin phosphodiesterase 4 multiple interactions ISO Fenofibrate promotes the reaction [Dextran Sulfate results in decreased expression of SMPD4 mRNA] CTD PMID:25035112 NCBI chr 2:130,151,392...130,181,757
Ensembl chr 2:130,151,392...130,182,750
JBrowse link
G SOCS3 suppressor of cytokine signaling 3 multiple interactions ISO [Fenofibrate co-treated with resveratrol] inhibits the reaction [Fructose results in increased expression of SOCS3 mRNA]; Fenofibrate inhibits the reaction [Fructose results in increased expression of SOCS3 mRNA] CTD PMID:26973390 NCBI chr17:78,356,778...78,360,925
Ensembl chr17:78,356,778...78,360,077
JBrowse link
G SOCS6 suppressor of cytokine signaling 6 increases expression
multiple interactions
ISO Fenofibrate results in increased expression of SOCS6 mRNA
PPARA protein affects the reaction [Fenofibrate results in increased expression of SOCS6 mRNA]
CTD PMID:21318169 NCBI chr18:70,289,045...70,330,199
Ensembl chr18:70,289,045...70,330,199
JBrowse link
G SOCS7 suppressor of cytokine signaling 7 decreases expression ISO Fenofibrate results in decreased expression of SOCS7 mRNA CTD PMID:21318169 NCBI chr17:38,351,844...38,405,593
Ensembl chr17:38,351,844...38,405,593
JBrowse link
G SOD2 superoxide dismutase 2 increases expression ISO Fenofibrate results in increased expression of SOD2 mRNA CTD PMID:17264098 NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529
JBrowse link
G SON SON DNA and RNA binding protein decreases expression ISO Fenofibrate results in decreased expression of SON mRNA CTD PMID:25596134 NCBI chr21:33,543,038...33,577,481
Ensembl chr21:33,543,038...33,577,481
JBrowse link
G SORL1 sortilin related receptor 1 increases expression
decreases expression
ISO
EXP
Fenofibrate results in increased expression of SORL1 mRNA
Fenofibrate results in decreased expression of SORL1 mRNA
CTD PMID:25596134 NCBI chr11:121,452,314...121,633,763
Ensembl chr11:121,452,314...121,633,763
JBrowse link
G SORT1 sortilin 1 increases expression ISO Fenofibrate results in increased expression of SORT1 mRNA CTD PMID:24986865 NCBI chr 1:109,309,575...109,397,918
Ensembl chr 1:109,309,568...109,397,918
JBrowse link
G SPMIP11 sperm microtubule inner protein 11 increases expression ISO Fenofibrate results in increased expression of SPMIP11 mRNA CTD PMID:32741897 NCBI chr12:48,727,435...48,771,459
Ensembl chr12:48,727,435...48,765,790
JBrowse link
G SPNS2 SPNS lysolipid transporter 2, sphingosine-1-phosphate increases expression EXP Fenofibrate results in increased expression of SPNS2 mRNA CTD PMID:25572481 NCBI chr17:4,498,881...4,539,035
Ensembl chr17:4,498,881...4,539,035
JBrowse link
G SPOP speckle type BTB/POZ protein increases expression
multiple interactions
ISO Fenofibrate results in increased expression of SPOP mRNA
PPARA protein affects the reaction [Fenofibrate results in increased expression of SPOP mRNA]
CTD PMID:21318169 NCBI chr17:49,598,884...49,678,163
Ensembl chr17:49,598,884...49,678,163
JBrowse link
G SPSB1 splA/ryanodine receptor domain and SOCS box containing 1 increases expression ISO Fenofibrate results in increased expression of SPSB1 mRNA CTD PMID:25596134 NCBI chr 1:9,292,894...9,369,532
Ensembl chr 1:9,292,894...9,369,532
JBrowse link
G SQLE squalene epoxidase increases expression
multiple interactions
ISO Fenofibrate results in increased expression of SQLE mRNA
NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of SQLE mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of SQLE mRNA]
CTD PMID:23063693 NCBI chr 8:124,998,505...125,022,283
Ensembl chr 8:124,998,497...125,022,283
JBrowse link
G SQSTM1 sequestosome 1 increases expression
multiple interactions
ISO Fenofibrate results in increased expression of SQSTM1 mRNA
Fenofibrate inhibits the reaction [tyloxapol results in increased expression of SQSTM1 protein]
CTD PMID:25596134 PMID:36905866 NCBI chr 5:179,806,393...179,838,078
Ensembl chr 5:179,806,398...179,838,078
JBrowse link
G SRD5A3 steroid 5 alpha-reductase 3 decreases expression ISO Fenofibrate results in decreased expression of SRD5A3 mRNA CTD PMID:25596134 NCBI chr 4:55,346,242...55,373,100
Ensembl chr 4:55,346,213...55,373,100
JBrowse link
G SREBF1 sterol regulatory element binding transcription factor 1 multiple interactions
increases expression
ISO
EXP
Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of SREBF1 mRNA]; Fenofibrate inhibits the reaction [tyloxapol results in increased expression of SREBF1 protein]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of SREBF1 mRNA]]; NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of SREBF1 mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of SREBF1 mRNA]
Fenofibrate inhibits the reaction [Fatty Acids, Nonesterified results in increased expression of SREBF1 mRNA]; Fenofibrate inhibits the reaction [Fatty Acids, Nonesterified results in increased expression of SREBF1 protein]
[Fenofibrate co-treated with resveratrol] inhibits the reaction [Fructose results in increased expression of SREBF1 mRNA]
CTD PMID:19593819 PMID:23063693 PMID:24735863 PMID:26973390 PMID:36905866 NCBI chr17:17,811,334...17,836,986
Ensembl chr17:17,810,399...17,837,002
JBrowse link
G SRXN1 sulfiredoxin 1 increases expression EXP Fenofibrate results in increased expression of SRXN1 mRNA CTD PMID:25596134 NCBI chr20:646,615...653,200
Ensembl chr20:646,615...653,200
JBrowse link
G ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4 decreases expression ISO Fenofibrate results in decreased expression of ST3GAL4 mRNA CTD PMID:11798191 NCBI chr11:126,355,686...126,414,638
Ensembl chr11:126,355,640...126,440,344
JBrowse link
G STAT5B signal transducer and activator of transcription 5B decreases activity ISO Fenofibrate results in decreased activity of STAT5B protein CTD PMID:30114225 NCBI chr17:42,199,177...42,288,370
Ensembl chr17:42,199,176...42,288,633
JBrowse link
G STK11 serine/threonine kinase 11 multiple interactions EXP Fenofibrate results in increased expression of and results in increased phosphorylation of STK11 protein CTD PMID:25545733 NCBI chr19:1,205,778...1,228,431
Ensembl chr19:1,177,558...1,228,431
JBrowse link
G STRBP spermatid perinuclear RNA binding protein increases expression EXP Fenofibrate results in increased expression of STRBP mRNA CTD PMID:25596134 NCBI chr 9:123,109,494...123,268,586
Ensembl chr 9:123,109,500...123,268,586
JBrowse link
G SUCLG1 succinate-CoA ligase GDP/ADP-forming subunit alpha affects expression
increases expression
ISO
EXP
Fenofibrate affects the expression of SUCLG1 mRNA
Fenofibrate results in increased expression of SUCLG1 protein
Fenofibrate results in increased expression of SUCLG1 mRNA
CTD PMID:16707586 PMID:20801182 PMID:24752549 NCBI chr 2:84,423,528...84,459,280
Ensembl chr 2:84,423,528...84,460,045
JBrowse link
G SULF2 sulfatase 2 decreases expression EXP
ISO
Fenofibrate results in decreased expression of SULF2 mRNA CTD PMID:25596134 NCBI chr20:47,657,406...47,786,627
Ensembl chr20:47,656,197...47,786,616
JBrowse link
G SULT1C2 sulfotransferase family 1C member 2 multiple interactions ISO [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of SULT1C2 mRNA CTD PMID:18253720 NCBI chr 2:108,288,895...108,309,915
Ensembl chr 2:108,288,639...108,309,915
JBrowse link
G SULT1E1 sulfotransferase family 1E member 1 multiple interactions ISO [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of SULT1E1 mRNA CTD PMID:18253720 NCBI chr 4:69,821,122...69,860,145
Ensembl chr 4:69,841,212...69,860,145
JBrowse link
G SULT4A1 sulfotransferase family 4A member 1 multiple interactions ISO [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of SULT4A1 mRNA CTD PMID:18253720 NCBI chr22:43,824,509...43,862,513
Ensembl chr22:43,824,509...43,862,513
JBrowse link
G TALDO1 transaldolase 1 decreases expression ISO Fenofibrate results in decreased expression of TALDO1 mRNA CTD PMID:25596134 NCBI chr11:747,464...765,012
Ensembl chr11:747,415...765,012
JBrowse link
G TARS1 threonyl-tRNA synthetase 1 decreases expression ISO Fenofibrate results in decreased expression of TARS1 mRNA CTD PMID:25596134 NCBI chr 5:33,440,696...33,468,091
Ensembl chr 5:33,440,696...33,468,091
JBrowse link
G TCP1 t-complex 1 multiple interactions ISO [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of TCP1 mRNA CTD PMID:18253720 NCBI chr 6:159,778,498...159,789,602
Ensembl chr 6:159,778,498...159,789,703
JBrowse link
G TDO2 tryptophan 2,3-dioxygenase increases expression EXP Fenofibrate results in increased expression of TDO2 mRNA CTD PMID:25572481 NCBI chr 4:155,903,696...155,920,406
Ensembl chr 4:155,854,738...155,920,406
JBrowse link
G TFE3 transcription factor binding to IGHM enhancer 3 affects expression
increases expression
ISO
EXP
Fenofibrate affects the expression of TFE3 mRNA
Fenofibrate results in increased expression of TFE3 mRNA
CTD PMID:25596134 NCBI chr  X:49,028,726...49,043,357
Ensembl chr  X:49,028,726...49,043,410
JBrowse link
G TGFB1 transforming growth factor beta 1 multiple interactions EXP
ISO
Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 mRNA]; Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]; Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of SERPINE1 mRNA]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of SERPINE1 mRNA]]
[Fenofibrate co-treated with resveratrol] inhibits the reaction [Fructose results in increased expression of TGFB1 mRNA]; Fenofibrate inhibits the reaction [Fructose results in increased expression of TGFB1 mRNA]
Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of TGFB1 mRNA]; Fenofibrate inhibits the reaction [TGFB1 protein results in decreased expression of TRIB3 mRNA]; Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]; Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of IL6 mRNA]; Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of SERPINE1 mRNA]; Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of TIMP1 mRNA]; NR0B2 protein inhibits the reaction [Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]]; NR0B2 protein inhibits the reaction [Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of IL6 mRNA]]; NR0B2 protein inhibits the reaction [Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of SERPINE1 mRNA]]; NR0B2 protein inhibits the reaction [Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of TIMP1 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of TGFB1 mRNA]]
CTD PMID:19593819 PMID:26973390 PMID:32613381 NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922
JBrowse link
G THRSP thyroid hormone responsive multiple interactions
decreases expression
EXP Fenofibrate promotes the reaction [Oleic Acid results in decreased expression of THRSP mRNA]
Fenofibrate results in decreased expression of THRSP mRNA
CTD PMID:24534255 PMID:25572481 NCBI chr11:78,063,861...78,068,351
Ensembl chr11:78,063,861...78,068,351
JBrowse link
G TIMP1 TIMP metallopeptidase inhibitor 1 multiple interactions ISO Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of TIMP1 mRNA]; Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of TIMP1 mRNA]; Fenofibrate inhibits the reaction [zoledronic acid results in increased expression of TIMP1 mRNA]; NR0B2 protein inhibits the reaction [Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of TIMP1 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of TIMP1 mRNA]] CTD PMID:19593819 PMID:28871336 NCBI chr  X:47,582,436...47,586,789
Ensembl chr  X:47,582,408...47,586,789
JBrowse link
G TIMP2 TIMP metallopeptidase inhibitor 2 multiple interactions ISO Fenofibrate inhibits the reaction [zoledronic acid results in increased expression of TIMP2 mRNA] CTD PMID:28871336 NCBI chr17:78,852,977...78,925,387
Ensembl chr17:78,852,977...78,925,387
JBrowse link
G TIPARP TCDD inducible poly(ADP-ribose) polymerase increases expression ISO Fenofibrate results in increased expression of TIPARP mRNA CTD PMID:25596134 NCBI chr 3:156,674,590...156,706,770
Ensembl chr 3:156,673,235...156,706,770
JBrowse link
G TLR4 toll like receptor 4 multiple interactions ISO Fenofibrate inhibits the reaction [Cyclophosphamide results in increased expression of TLR4 protein] CTD PMID:38278497 NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735
JBrowse link
G TMEM120A transmembrane protein 120A decreases expression
increases expression
EXP
ISO
Fenofibrate results in decreased expression of TMEM120A mRNA
Fenofibrate results in increased expression of TMEM120A mRNA
CTD PMID:25572481 PMID:32741897 NCBI chr 7:75,986,831...75,994,595
Ensembl chr 7:75,986,831...75,994,656
JBrowse link
G TNF tumor necrosis factor multiple interactions
decreases expression
decreases response to substance
EXP
ISO
Fenofibrate affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA]; Fenofibrate inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of CD36 mRNA]; Fenofibrate inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein]; Fenofibrate inhibits the reaction [TNF protein results in increased expression of CCL5 mRNA]; Fenofibrate inhibits the reaction [TNF protein results in increased expression of CCL5 protein]; Fenofibrate inhibits the reaction [TNF protein results in increased expression of SERPINE1 mRNA]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [TNF protein results in increased expression of SERPINE1 mRNA]]
[Fenofibrate co-treated with Resveratrol] inhibits the reaction [Fructose results in increased expression of and results in increased secretion of TNF protein]; [Fenofibrate co-treated with Sodium Glutamate] results in increased expression of TNF protein; Fenofibrate inhibits the reaction [Doxorubicin results in increased expression of TNF protein]; Fenofibrate inhibits the reaction [Fructose results in increased expression of and results in increased secretion of TNF protein]; Fenofibrate promotes the reaction [Pioglitazone inhibits the reaction [Doxorubicin results in increased expression of TNF protein]]; Pioglitazone promotes the reaction [Fenofibrate inhibits the reaction [Doxorubicin results in increased expression of TNF protein]]
Fenofibrate results in decreased expression of TNF mRNA; Fenofibrate results in decreased expression of TNF protein
[Fenofibrate co-treated with Alitretinoin] inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]; Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of TNF mRNA]; Fenofibrate inhibits the reaction [Cyclophosphamide results in increased expression of TNF protein]; Fenofibrate inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; Fenofibrate inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]; Fenofibrate inhibits the reaction [triptolide results in increased expression of TNF mRNA]; Fenofibrate promotes the reaction [Dextran Sulfate results in increased expression of TNF protein]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of TNF mRNA]]
Fenofibrate results in decreased susceptibility to TNF protein; TNF protein results in decreased susceptibility to Fenofibrate
CTD PMID:12586603 PMID:15968640 PMID:18356826 PMID:19593819 PMID:20520642 More... NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
JBrowse link
G TNFRSF10B TNF receptor superfamily member 10b increases expression EXP Fenofibrate results in increased expression of TNFRSF10B mRNA CTD PMID:25596134 NCBI chr 8:23,020,133...23,069,031
Ensembl chr 8:23,020,133...23,069,031
JBrowse link
G TNFRSF11B TNF receptor superfamily member 11b decreases expression EXP Fenofibrate results in decreased expression of TNFRSF11B mRNA CTD PMID:25572481 NCBI chr 8:118,923,557...118,951,885
Ensembl chr 8:118,923,557...118,951,885
JBrowse link
G TNFRSF21 TNF receptor superfamily member 21 increases expression EXP Fenofibrate results in increased expression of TNFRSF21 mRNA CTD PMID:25572481 PMID:25596134 NCBI chr 6:47,231,532...47,309,905
Ensembl chr 6:47,231,532...47,309,905
JBrowse link
G TNNI3 troponin I3, cardiac type multiple interactions ISO Fenofibrate inhibits the reaction [Cyclophosphamide results in increased expression of TNNI3 protein] CTD PMID:38278497 NCBI chr19:55,151,767...55,157,732
Ensembl chr19:55,151,767...55,157,773
JBrowse link
G TOP1 DNA topoisomerase I multiple interactions
increases expression
ISO [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of TOP1 mRNA
Fenofibrate results in increased expression of TOP1 mRNA
CTD PMID:18253720 PMID:25596134 NCBI chr20:41,028,822...41,124,487
Ensembl chr20:41,028,822...41,124,487
JBrowse link
G TOP2A DNA topoisomerase II alpha increases expression ISO Fenofibrate results in increased expression of TOP2A mRNA CTD PMID:32741897 NCBI chr17:40,388,525...40,417,896
Ensembl chr17:40,388,525...40,417,896
JBrowse link
G TOPORS TOP1 binding arginine/serine rich protein, E3 ubiquitin ligase increases expression
multiple interactions
ISO Fenofibrate results in increased expression of TOPORS mRNA
[PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of TOPORS mRNA
CTD PMID:21318169 NCBI chr 9:32,540,544...32,552,586
Ensembl chr 9:32,540,544...32,552,586
JBrowse link
G TOR1B torsin family 1 member B increases expression
multiple interactions
ISO Fenofibrate results in increased expression of TOR1B mRNA
PPARA protein affects the reaction [Fenofibrate results in increased expression of TOR1B mRNA]
CTD PMID:21318169 NCBI chr 9:129,803,184...129,811,281
Ensembl chr 9:129,803,157...129,811,281
JBrowse link
G TOR3A torsin family 3 member A increases expression
multiple interactions
ISO Fenofibrate results in increased expression of TOR3A mRNA
PPARA protein affects the reaction [Fenofibrate results in increased expression of TOR3A mRNA]
CTD PMID:21318169 NCBI chr 1:179,082,070...179,095,996
Ensembl chr 1:179,082,070...179,098,023
JBrowse link
G TP53 tumor protein p53 increases expression
affects activity
ISO
EXP
Fenofibrate results in increased expression of TP53 mRNA
Fenofibrate affects the activity of TP53 protein
CTD PMID:17264098 PMID:25596134 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,546
JBrowse link
G TP53I3 tumor protein p53 inducible protein 3 decreases expression EXP Fenofibrate results in decreased expression of TP53I3 mRNA CTD PMID:25596134 NCBI chr 2:24,077,433...24,084,834
Ensembl chr 2:24,077,433...24,085,861
JBrowse link
G TP53INP1 tumor protein p53 inducible nuclear protein 1 increases expression
affects expression
decreases expression
ISO
EXP
Fenofibrate results in increased expression of TRP53INP1 mRNA
Fenofibrate affects the expression of TP53INP1 mRNA
Fenofibrate results in decreased expression of TP53INP1 mRNA
CTD PMID:17264098 PMID:25596134 NCBI chr 8:94,925,972...94,949,378
Ensembl chr 8:94,925,972...94,949,378
JBrowse link
G TRAFD1 TRAF-type zinc finger domain containing 1 decreases expression ISO Fenofibrate results in decreased expression of TRAFD1 mRNA CTD PMID:25596134 NCBI chr12:112,125,560...112,153,604
Ensembl chr12:112,125,538...112,153,604
JBrowse link
G TRIAP1 TP53 regulated inhibitor of apoptosis 1 decreases expression EXP Fenofibrate results in decreased expression of TRIAP1 mRNA CTD PMID:25596134 NCBI chr12:120,443,964...120,446,384
Ensembl chr12:120,443,964...120,446,384
JBrowse link
G TRIB3 tribbles pseudokinase 3 multiple interactions
decreases expression
ISO
EXP
[Fenofibrate results in increased activity of PPARA protein] which results in increased expression of TRIB3 mRNA; Fenofibrate inhibits the reaction [TGFB1 protein results in decreased expression of TRIB3 mRNA]
Fenofibrate results in decreased expression of TRIB3 mRNA
Fenofibrate inhibits the reaction [Arsenic Trioxide results in increased expression of TRIB3 mRNA]; Fenofibrate inhibits the reaction [Arsenic Trioxide results in increased expression of TRIB3 protein]
CTD PMID:19593819 PMID:32929351 NCBI chr20:380,760...397,559
Ensembl chr20:362,835...397,559
JBrowse link
G TRIM24 tripartite motif containing 24 increases expression EXP Fenofibrate results in increased expression of TRIM24 mRNA CTD PMID:25572481 NCBI chr 7:138,460,259...138,589,996
Ensembl chr 7:138,460,259...138,589,996
JBrowse link
G TRIM63 tripartite motif containing 63 increases expression
multiple interactions
ISO Fenofibrate results in increased expression of TRIM63 mRNA; Fenofibrate results in increased expression of TRIM63 protein
Lovastatin promotes the reaction [Fenofibrate results in increased expression of TRIM63 protein]; PPARA protein affects the reaction [Fenofibrate results in increased expression of TRIM63 mRNA]
CTD PMID:33408297 NCBI chr 1:26,051,301...26,067,630
Ensembl chr 1:26,051,301...26,068,436
JBrowse link
G TRIP12 thyroid hormone receptor interactor 12 increases expression
multiple interactions
ISO Fenofibrate results in increased expression of TRIP12 mRNA
PPARA protein affects the reaction [Fenofibrate results in increased expression of TRIP12 mRNA]
CTD PMID:21318169 NCBI chr 2:229,763,837...229,923,186
Ensembl chr 2:229,763,837...229,923,239
JBrowse link
G TXNIP thioredoxin interacting protein increases expression ISO
EXP
Fenofibrate results in increased expression of TXNIP mRNA CTD PMID:17264098 PMID:25572481 NCBI chr 1:145,992,435...145,996,579
Ensembl chr 1:145,992,435...145,996,579
JBrowse link
G TXNRD1 thioredoxin reductase 1 increases expression EXP Fenofibrate results in increased expression of TXNRD1 mRNA CTD PMID:25596134 NCBI chr12:104,215,779...104,350,307
Ensembl chr12:104,215,779...104,350,307
JBrowse link
G TYR tyrosinase multiple interactions
decreases expression
ISO [Fenofibrate results in decreased chemical synthesis of Melanins] which results in decreased expression of TYR; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Fenofibrate results in decreased expression of TYR protein]; Fenofibrate results in decreased expression of and results in decreased activity of TYR protein
Fenofibrate results in decreased expression of TYR mRNA
CTD PMID:23872139 NCBI chr11:89,177,875...89,295,759
Ensembl chr11:89,177,875...89,295,759
JBrowse link
G UBA5 ubiquitin like modifier activating enzyme 5 decreases expression ISO Fenofibrate results in decreased expression of UBA5 mRNA CTD PMID:21318169 NCBI chr 3:132,654,430...132,679,794
Ensembl chr 3:132,654,446...132,679,794
JBrowse link
G UBE2G2 ubiquitin conjugating enzyme E2 G2 affects expression ISO Fenofibrate affects the expression of UBE2G2 mRNA CTD PMID:25596134 NCBI chr21:44,768,580...44,801,820
Ensembl chr21:44,768,580...44,801,826
JBrowse link
G UBE2Q2 ubiquitin conjugating enzyme E2 Q2 increases expression
multiple interactions
ISO Fenofibrate results in increased expression of UBE2Q2 mRNA
PPARA protein affects the reaction [Fenofibrate results in increased expression of UBE2Q2 mRNA]
CTD PMID:21318169 NCBI chr15:75,843,447...75,901,078
Ensembl chr15:75,843,307...75,901,078
JBrowse link
G UBE2R2 ubiquitin conjugating enzyme E2 R2 decreases expression
multiple interactions
ISO Fenofibrate results in decreased expression of UBE2R2 mRNA
PPARA protein affects the reaction [Fenofibrate results in decreased expression of UBE2R2 mRNA]
CTD PMID:21318169 NCBI chr 9:33,815,168...33,920,399
Ensembl chr 9:33,817,160...33,920,399
JBrowse link
G UBE2W ubiquitin conjugating enzyme E2 W increases expression ISO Fenofibrate results in increased expression of UBE2W mRNA CTD PMID:21318169 NCBI chr 8:73,780,096...73,878,862
Ensembl chr 8:73,780,097...73,878,910
JBrowse link
G UBE3A ubiquitin protein ligase E3A increases expression
multiple interactions
ISO Fenofibrate results in increased expression of UBE3A mRNA
PPARA protein affects the reaction [Fenofibrate results in increased expression of UBE3A mRNA]
CTD PMID:21318169 NCBI chr15:25,333,728...25,439,056
Ensembl chr15:25,333,728...25,439,051
JBrowse link
G UBR2 ubiquitin protein ligase E3 component n-recognin 2 multiple interactions
increases expression
ISO [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of UBR2 mRNA
Fenofibrate results in increased expression of UBR2 mRNA
CTD PMID:21318169 NCBI chr 6:42,564,029...42,693,505
Ensembl chr 6:42,564,029...42,693,505
JBrowse link
G UCP2 uncoupling protein 2 multiple interactions
increases expression
ISO
EXP
[Fenofibrate binds to and results in increased activity of PPARA protein] which results in increased expression of UCP2 mRNA; [Fenofibrate co-treated with Sodium Glutamate] results in increased expression of UCP2 mRNA
PPARA protein promotes the reaction [Fenofibrate results in increased expression of UCP2 protein]
Fenofibrate results in increased expression of UCP2 mRNA; Fenofibrate results in increased expression of UCP2 protein
PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of UCP2 mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of UCP2 protein]
CTD PMID:11341955 PMID:16595124 PMID:21999347 PMID:24752549 PMID:32741897 NCBI chr11:73,974,672...73,983,202
Ensembl chr11:73,974,061...73,982,843
JBrowse link
G UCP3 uncoupling protein 3 increases expression
multiple interactions
ISO Fenofibrate results in increased expression of UCP3 mRNA
fenofibrate co-treated with fructose increases expression of Ucp3 mRNA in liver and muscle
fenofibrate increases expression of Ucp3 mRNA in muscle
CTD
RGD
PMID:16595124 PMID:11934685 PMID:11934685 RGD:628329, RGD:628329 NCBI chr11:74,000,277...74,009,085
Ensembl chr11:74,000,277...74,009,085
JBrowse link
G UGT1A1 UDP glucuronosyltransferase family 1 member A1 increases expression EXP Fenofibrate results in increased expression of UGT1A1 mRNA CTD PMID:25572481 NCBI chr 2:233,760,270...233,773,300
Ensembl chr 2:233,760,270...233,773,300
JBrowse link
G UGT1A3 UDP glucuronosyltransferase family 1 member A3 increases expression EXP Fenofibrate results in increased expression of UGT1A3 mRNA CTD PMID:17058234 NCBI chr 2:233,729,042...233,773,300
Ensembl chr 2:233,729,042...233,773,300
JBrowse link
G UGT1A6 UDP glucuronosyltransferase family 1 member A6 multiple interactions
increases expression
ISO [Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of UGT1A6 mRNA
Fenofibrate results in increased expression of UGT1A6 mRNA
CTD PMID:18253720 PMID:18775883 NCBI chr 2:233,691,702...233,773,300
Ensembl chr 2:233,691,607...233,773,300
JBrowse link
G UGT2B4 UDP glucuronosyltransferase family 2 member B4 increases expression EXP Fenofibrate results in increased expression of UGT2B4 mRNA CTD PMID:17058234 NCBI chr 4:69,480,165...69,526,014
Ensembl chr 4:69,480,165...69,526,014
JBrowse link
G URAD ureidoimidazoline (2-oxo-4-hydroxy-4-carboxy-5-) decarboxylase increases expression ISO Fenofibrate results in increased expression of URAD mRNA CTD PMID:32741897 NCBI chr13:27,977,717...27,988,693
Ensembl chr13:27,977,717...27,988,693
JBrowse link
G URI1 URI1 prefoldin like chaperone increases expression
multiple interactions
ISO Fenofibrate results in increased expression of URI1 mRNA
PPARA protein affects the reaction [Fenofibrate results in increased expression of URI1 mRNA]
CTD PMID:21318169 NCBI chr19:29,923,657...30,016,612
Ensembl chr19:29,923,644...30,016,612
JBrowse link
G URM1 ubiquitin related modifier 1 decreases expression
multiple interactions
ISO Fenofibrate results in decreased expression of URM1 mRNA
PPARA protein affects the reaction [Fenofibrate results in decreased expression of URM1 mRNA]
CTD PMID:21318169 NCBI chr 9:128,371,319...128,392,016
Ensembl chr 9:128,371,361...128,392,016
JBrowse link
G USP1 ubiquitin specific peptidase 1 increases expression
multiple interactions
ISO Fenofibrate results in increased expression of USP1 mRNA
PPARA protein affects the reaction [Fenofibrate results in increased expression of USP1 mRNA]
CTD PMID:21318169 NCBI chr 1:62,436,395...62,451,804
Ensembl chr 1:62,436,297...62,451,804
JBrowse link
G USP10 ubiquitin specific peptidase 10 increases expression
multiple interactions
ISO Fenofibrate results in increased expression of USP10 mRNA
PPARA protein affects the reaction [Fenofibrate results in increased expression of USP10 mRNA]
CTD PMID:21318169 NCBI chr16:84,700,000...84,779,922
Ensembl chr16:84,699,986...84,779,922
JBrowse link
G USP22 ubiquitin specific peptidase 22 increases expression
multiple interactions
ISO Fenofibrate results in increased expression of USP22 mRNA
PPARA protein affects the reaction [Fenofibrate results in increased expression of USP22 mRNA]
CTD PMID:21318169 NCBI chr17:20,999,596...21,043,419
Ensembl chr17:20,999,596...21,043,760
JBrowse link
G USP3 ubiquitin specific peptidase 3 increases expression ISO Fenofibrate results in increased expression of USP3 mRNA CTD PMID:25596134 NCBI chr15:63,504,593...63,594,633
Ensembl chr15:63,504,511...63,594,640
JBrowse link
G USP36 ubiquitin specific peptidase 36 decreases expression
multiple interactions
ISO Fenofibrate results in decreased expression of USP36 mRNA
PPARA protein affects the reaction [Fenofibrate results in decreased expression of USP36 mRNA]
CTD PMID:21318169 NCBI chr17:78,787,381...78,841,439
Ensembl chr17:78,787,381...78,841,441
JBrowse link
G USP38 ubiquitin specific peptidase 38 increases expression
multiple interactions
ISO Fenofibrate results in increased expression of USP38 mRNA
PPARA protein affects the reaction [Fenofibrate results in increased expression of USP38 mRNA]
CTD PMID:21318169 NCBI chr 4:143,184,917...143,223,874
Ensembl chr 4:143,184,917...143,225,212
JBrowse link
G USP4 ubiquitin specific peptidase 4 increases expression ISO Fenofibrate results in increased expression of USP4 mRNA CTD PMID:32741897 NCBI chr 3:49,277,144...49,340,053
Ensembl chr 3:49,277,144...49,340,712
JBrowse link
G USP7 ubiquitin specific peptidase 7 increases expression
multiple interactions
ISO Fenofibrate results in increased expression of USP7 mRNA
PPARA protein affects the reaction [Fenofibrate results in increased expression of USP7 mRNA]
CTD PMID:21318169 NCBI chr16:8,892,097...8,963,906
Ensembl chr16:8,892,097...8,975,328
JBrowse link
G USP9X ubiquitin specific peptidase 9 X-linked increases expression
multiple interactions
ISO Fenofibrate results in increased expression of USP9X mRNA
PPARA protein affects the reaction [Fenofibrate results in increased expression of USP9X mRNA]
CTD PMID:21318169 NCBI chr  X:41,085,445...41,236,579
Ensembl chr  X:41,085,445...41,236,579
JBrowse link
G USPL1 ubiquitin specific peptidase like 1 increases expression
multiple interactions
ISO Fenofibrate results in increased expression of USPL1 mRNA
PPARA protein affects the reaction [Fenofibrate results in increased expression of USPL1 mRNA]
CTD PMID:21318169 NCBI chr13:30,617,920...30,660,766
Ensembl chr13:30,617,693...30,660,770
JBrowse link
G VARS1 valyl-tRNA synthetase 1 increases expression ISO
EXP
Fenofibrate results in increased expression of VARS1 mRNA CTD PMID:25596134 NCBI chr 6:31,777,518...31,795,752
Ensembl chr 6:31,777,518...31,795,752
JBrowse link
G VCAM1 vascular cell adhesion molecule 1 multiple interactions ISO
EXP
Fenofibrate inhibits the reaction [Lipopolysaccharides results in increased expression of VCAM1 mRNA]
dorsomorphin inhibits the reaction [Fenofibrate inhibits the reaction [ALB protein modified form results in increased expression of VCAM1 mRNA]]; Fenofibrate inhibits the reaction [ALB protein modified form results in increased expression of VCAM1 mRNA]
CTD PMID:20580385 PMID:21300114 NCBI chr 1:100,719,742...100,739,045
Ensembl chr 1:100,719,742...100,739,045
JBrowse link
G VCPIP1 valosin containing protein interacting protein 1 increases expression
multiple interactions
ISO Fenofibrate results in increased expression of VCPIP1 mRNA
PPARA protein affects the reaction [Fenofibrate results in increased expression of VCPIP1 mRNA]
CTD PMID:21318169 NCBI chr 8:66,628,487...66,667,231
Ensembl chr 8:66,628,487...66,667,231
JBrowse link
G VEGFA vascular endothelial growth factor A multiple interactions ISO Fenofibrate inhibits the reaction [AHR protein affects the reaction [AGT protein results in increased expression of VEGFA protein]] CTD PMID:31016362 NCBI chr 6:43,770,211...43,786,487
Ensembl chr 6:43,770,184...43,786,487
JBrowse link
G VEGFB vascular endothelial growth factor B increases expression ISO Fenofibrate results in increased expression of VEGFB mRNA CTD PMID:17264098 PMID:25596134 NCBI chr11:64,234,584...64,239,264
Ensembl chr11:64,234,584...64,239,264
JBrowse link
G VNN1 vanin 1 increases expression ISO
EXP
Fenofibrate results in increased expression of VNN1 mRNA CTD PMID:11798191 PMID:25572481 PMID:27665778 PMID:32741897 NCBI chr 6:132,680,849...132,714,055
Ensembl chr 6:132,680,849...132,714,055
JBrowse link
G VSIR V-set immunoregulatory receptor decreases expression EXP Fenofibrate results in decreased expression of VSIR mRNA CTD PMID:25572481 NCBI chr10:71,747,556...71,773,520
Ensembl chr10:71,747,556...71,773,520
JBrowse link
G VWA8 von Willebrand factor A domain containing 8 increases expression ISO Fenofibrate results in increased expression of VWA8 mRNA CTD PMID:32741897 NCBI chr13:41,566,835...41,961,109
Ensembl chr13:41,566,835...41,961,120
JBrowse link
G WSB1 WD repeat and SOCS box containing 1 decreases expression
multiple interactions
ISO Fenofibrate results in decreased expression of WSB1 mRNA
PPARA protein affects the reaction [Fenofibrate results in decreased expression of WSB1 mRNA]
CTD PMID:21318169 NCBI chr17:27,294,114...27,315,926
Ensembl chr17:27,294,076...27,315,926
JBrowse link
G WSB2 WD repeat and SOCS box containing 2 increases expression ISO Fenofibrate results in increased expression of WSB2 mRNA CTD PMID:21318169 NCBI chr12:118,032,687...118,062,174
Ensembl chr12:118,032,687...118,062,430
JBrowse link
G WWC2 WW and C2 domain containing 2 decreases expression ISO Fenofibrate results in decreased expression of WWC2 mRNA CTD PMID:25596134 NCBI chr 4:183,099,257...183,320,777
Ensembl chr 4:183,099,257...183,320,777
JBrowse link
G XBP1 X-box binding protein 1 affects activity
decreases expression
ISO
EXP
Fenofibrate affects the activity of XBP1 protein
Fenofibrate results in decreased expression of XBP1 mRNA
CTD PMID:25596134 NCBI chr22:28,794,560...28,800,569
Ensembl chr22:28,794,555...28,800,597
JBrowse link
G XPC XPC complex subunit, DNA damage recognition and repair factor decreases expression ISO Fenofibrate results in decreased expression of XPC mRNA CTD PMID:25596134 NCBI chr 3:14,145,147...14,178,601
Ensembl chr 3:14,145,145...14,178,621
JBrowse link
G XRCC5 X-ray repair cross complementing 5 multiple interactions
increases expression
ISO [Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of XRCC5 mRNA
Fenofibrate results in increased expression of XRCC5 mRNA
CTD PMID:17264098 PMID:18253720 PMID:18775883 NCBI chr 2:216,109,348...216,206,293
Ensembl chr 2:216,107,464...216,206,303
JBrowse link
G YARS1 tyrosyl-tRNA synthetase 1 increases expression EXP
ISO
Fenofibrate results in increased expression of YARS1 mRNA CTD PMID:25596134 NCBI chr 1:32,775,239...32,817,358
Ensembl chr 1:32,775,237...32,818,031
JBrowse link
G ZNF385D zinc finger protein 385D increases expression EXP Fenofibrate results in increased expression of ZNF385D mRNA CTD PMID:25572481 NCBI chr 3:21,412,218...22,372,763
Ensembl chr 3:21,412,218...22,373,321
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 26504
    role 26326
      biological role 26305
        xenobiotic 20407
          fenofibrate 724
Path 2
Term Annotations click to browse term
  CHEBI ontology 26504
    subatomic particle 26480
      composite particle 26480
        hadron 26480
          baryon 26480
            nucleon 26480
              atomic nucleus 26480
                atom 26480
                  main group element atom 26217
                    p-block element atom 26217
                      carbon group element atom 25660
                        carbon atom 25622
                          organic molecular entity 25622
                            heteroorganic entity 25005
                              organochalcogen compound 24601
                                organooxygen compound 24195
                                  carbon oxoacid 22808
                                    carboxylic acid 22788
                                      monocarboxylic acid 21781
                                        fatty acid 19164
                                          fatty acid derivative 9266
                                            fatty alcohol 6167
                                              secondary fatty alcohol 813
                                                propan-2-ol 813
                                                  isopropyl ester 778
                                                    fenofibrate 724
paths to the root