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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:disulfiram
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Accession:CHEBI:4659 term browser browse the term
Definition:An organic disulfide that results from the formal oxidative dimerisation of N,N-diethyldithiocarbamic acid. A multi-enzyme inhibitor that is used in alcohol aversion therapy and also exhibits anticancer properties.
Synonyms:exact_synonym: 1,1',1'',1'''-[disulfanediylbis(carbonothioylnitrilo)]tetraethane
 related_synonym: 1,1'-dithiobis(N,N-diethylthioformamide);   Antabuse;   Formula=C10H20N2S4;   InChI=1S/C10H20N2S4/c1-5-11(6-2)9(13)15-16-10(14)12(7-3)8-4/h5-8H2,1-4H3;   InChIKey=AUZONCFQVSMFAP-UHFFFAOYSA-N;   N,N,N',N'-tetraethylthiuram disulfide;   SMILES=S(SC(N(CC)CC)=S)C(N(CC)CC)=S;   bis(diethylthiocarbamoyl) disulfide;   tetraethylthioperoxydicarbonic diamide;   tetraethylthiuram disulfide;   tetraethylthiuram disulphide
 xref: CAS:97-77-8;   DrugBank:DB00822;   Drug_Central:928;   HMDB:HMDB0014960;   KEGG:C01692;   KEGG:D00131;   LINCS:LSM-5467
 xref_mesh: MESH:D004221
 xref: MetaCyc:DISULFIRAM;   PMID:10841824;   PMID:11005259;   PMID:11716515;   PMID:14978246;   PMID:15325261;   PMID:15709459;   PMID:16426571;   PMID:16661923;   PMID:16666414;   PMID:16880974;   PMID:17079463;   PMID:17579916;   PMID:17667894;   PMID:18579431;   PMID:19720750;   PMID:19782464;   PMID:19787200;   PMID:21471244;   PMID:24496638;   PMID:25133664;   PMID:25445071;   PMID:25464072;   PMID:25476326;   PMID:25495604;   PMID:25557293;   PMID:25565438;   PMID:25657800;   PMID:25777347;   PMID:26033731;   PMID:26224731;   PMID:26235918;   PMID:26239994;   PMID:26314552;   PMID:26517513;   PMID:26550292;   PMID:31151194;   PMID:32963852;   PMID:32971817;   PMID:33731397;   PMID:34012274;   PMID:34045896;   PMID:8442800;   PMID:8572926;   Pesticides:disulfiram;   Reaxys:1712560;   Wikipedia:Disulfiram



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disulfiram term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AARS1 alanyl-tRNA synthetase 1 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of AARS1 mRNA CTD PMID:24690739 NCBI chr16:70,252,298...70,289,506
Ensembl chr16:70,251,983...70,289,707
JBrowse link
G ABAT 4-aminobutyrate aminotransferase multiple interactions ISO [Ethanol co-treated with Disulfiram] results in decreased activity of ABAT protein; [Ethanol co-treated with Disulfiram] results in decreased expression of ABAT mRNA CTD PMID:9591243 NCBI chr16:8,674,617...8,784,570
Ensembl chr16:8,674,596...8,784,575
JBrowse link
G ABCA1 ATP binding cassette subfamily A member 1 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of ABCA1 mRNA CTD PMID:24690739 NCBI chr 9:104,781,006...104,928,155
Ensembl chr 9:104,781,006...104,928,155
JBrowse link
G ABCA3 ATP binding cassette subfamily A member 3 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of ABCA3 mRNA CTD PMID:24690739 NCBI chr16:2,275,881...2,340,728
Ensembl chr16:2,275,881...2,340,746
JBrowse link
G ABCB1 ATP binding cassette subfamily B member 1 multiple interactions
decreases activity
EXP Disulfiram affects the reaction [ABCB1 protein results in increased hydrolysis of Adenosine Triphosphate]; Disulfiram inhibits the reaction [8-azidoadenosine 5'-triphosphate binds to ABCB1 protein]; Disulfiram inhibits the reaction [azidopine binds to ABCB1 protein]; Disulfiram inhibits the reaction [azidoprazosin binds to ABCB1 protein]
Disulfiram metabolite results in decreased activity of ABCB1 protein; Disulfiram results in decreased activity of ABCB1 protein
CTD PMID:10841824 PMID:14978246 PMID:16028354 NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323
JBrowse link
G ABCB11 ATP binding cassette subfamily B member 11 decreases activity
multiple interactions
EXP Disulfiram results in decreased activity of ABCB11 protein
Disulfiram inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid]
CTD PMID:24014644 NCBI chr 2:168,915,390...169,031,324
Ensembl chr 2:168,915,498...169,031,324
JBrowse link
G ABCC1 ATP binding cassette subfamily C member 1 (ABCC1 blood group) decreases activity
multiple interactions
EXP Disulfiram results in decreased activity of ABCC1 protein
Disulfiram affects the reaction [ABCC1 protein results in increased hydrolysis of Adenosine Triphosphate]; Disulfiram inhibits the reaction [8-azidoadenosine 5'-triphosphate binds to ABCC1 protein]
CTD PMID:14978246 NCBI chr16:15,949,143...16,143,053
Ensembl chr16:15,949,138...16,143,257
JBrowse link
G ABCC4 ATP binding cassette subfamily C member 4 (PEL blood group) multiple interactions EXP Disulfiram inhibits the reaction [8-azidoadenosine 5'-triphosphate binds to ABCC4 protein]; Disulfiram inhibits the reaction [ABCC4 protein results in increased hydrolysis of Adenosine Triphosphate] CTD PMID:14978246 NCBI chr13:95,019,835...95,301,451
Ensembl chr13:95,019,835...95,301,475
JBrowse link
G ABCG1 ATP binding cassette subfamily G member 1 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of ABCG1 mRNA CTD PMID:24690739 NCBI chr21:42,199,689...42,297,244
Ensembl chr21:42,199,689...42,304,389
JBrowse link
G ACAD11 acyl-CoA dehydrogenase family member 11 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of ACAD11 mRNA CTD PMID:24690739 NCBI chr 3:132,558,141...132,659,809
Ensembl chr 3:132,558,138...132,660,082
JBrowse link
G ACE2 angiotensin converting enzyme 2 decreases expression EXP Disulfiram results in decreased expression of ACE2 mRNA CTD PMID:32808185 NCBI chr  X:15,518,197...15,607,211
Ensembl chr  X:15,494,566...15,607,236
JBrowse link
G ACHE acetylcholinesterase (Yt blood group) decreases expression ISO Disulfiram results in decreased expression of ACHE protein CTD PMID:3868355 NCBI chr 7:100,889,994...100,896,994
Ensembl chr 7:100,889,994...100,896,974
JBrowse link
G ACSS2 acyl-CoA synthetase short chain family member 2 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of ACSS2 mRNA CTD PMID:24690739 NCBI chr20:34,874,989...34,927,959
Ensembl chr20:34,872,146...34,927,962
JBrowse link
G ACTA2 actin alpha 2, smooth muscle multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of ACTA2 mRNA CTD PMID:24690739 NCBI chr10:88,935,074...88,991,337
Ensembl chr10:88,934,822...88,991,339
JBrowse link
G ADAM9 ADAM metallopeptidase domain 9 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of ADAM9 mRNA CTD PMID:24690739 NCBI chr 8:38,996,973...39,105,261
Ensembl chr 8:38,996,754...39,105,445
JBrowse link
G ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif 1 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of ADAMTS1 mRNA CTD PMID:24690739 NCBI chr21:26,835,755...26,845,409
Ensembl chr21:26,835,755...26,845,409
JBrowse link
G ADARB1 adenosine deaminase RNA specific B1 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of ADARB1 mRNA CTD PMID:24690739 NCBI chr21:45,074,578...45,226,563
Ensembl chr21:45,073,853...45,226,560
JBrowse link
G ADCY3 adenylate cyclase 3 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of ADCY3 mRNA CTD PMID:24690739 NCBI chr 2:24,819,169...24,920,237
Ensembl chr 2:24,819,169...24,920,237
JBrowse link
G ADGRE5 adhesion G protein-coupled receptor E5 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of ADGRE5 mRNA CTD PMID:24690739 NCBI chr19:14,381,444...14,408,723
Ensembl chr19:14,380,501...14,408,725
JBrowse link
G ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide decreases activity ISO Disulfiram results in decreased activity of ADH1 protein CTD PMID:15551062 NCBI chr 4:99,336,497...99,352,746
Ensembl chr 4:99,336,497...99,352,746
JBrowse link
G ADM adrenomedullin multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of ADM mRNA CTD PMID:24690739 NCBI chr11:10,305,073...10,307,397
Ensembl chr11:10,305,073...10,307,397
JBrowse link
G AFAP1 actin filament associated protein 1 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of AFAP1 mRNA CTD PMID:24690739 NCBI chr 4:7,758,713...7,939,861
Ensembl chr 4:7,758,714...7,939,926
JBrowse link
G AGXT alanine--glyoxylate aminotransferase multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of AGXT mRNA CTD PMID:24690739 NCBI chr 2:240,868,824...240,880,500
Ensembl chr 2:240,868,824...240,880,502
JBrowse link
G AGXT2 alanine--glyoxylate aminotransferase 2 multiple interactions ISO [Ethanol co-treated with Disulfiram] results in decreased activity of AGXT2 protein CTD PMID:9591243 NCBI chr 5:34,998,102...35,047,949
Ensembl chr 5:34,998,101...35,048,135
JBrowse link
G AHSA1 activator of HSP90 ATPase activity 1 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of AHSA1 mRNA CTD PMID:24690739 NCBI chr14:77,457,867...77,469,472
Ensembl chr14:77,457,870...77,469,472
JBrowse link
G AKR1B1 aldo-keto reductase family 1 member B increases expression EXP Disulfiram results in increased expression of AKR1B1 mRNA CTD PMID:20566472 NCBI chr 7:134,442,350...134,459,239
Ensembl chr 7:134,442,356...134,459,284
JBrowse link
G AKR1B10 aldo-keto reductase family 1 member B10 increases expression EXP Disulfiram results in increased expression of AKR1B10 mRNA CTD PMID:20566472 NCBI chr 7:134,527,567...134,541,412
Ensembl chr 7:134,527,567...134,541,412
JBrowse link
G AKR1C1 aldo-keto reductase family 1 member C1 increases expression EXP Disulfiram results in increased expression of AKR1C1 mRNA CTD PMID:20566472 NCBI chr10:4,963,415...4,983,283
Ensembl chr10:4,963,253...4,983,283
JBrowse link
G AKR1C3 aldo-keto reductase family 1 member C3 increases expression EXP Disulfiram results in increased expression of AKR1C3 mRNA CTD PMID:20566472 NCBI chr10:5,048,781...5,107,686
Ensembl chr10:5,035,354...5,107,686
JBrowse link
G AKT1 AKT serine/threonine kinase 1 decreases phosphorylation EXP Disulfiram results in decreased phosphorylation of AKT1 protein CTD PMID:34182011 NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,759
JBrowse link
G ALAD aminolevulinate dehydratase multiple interactions ISO [Disulfiram co-treated with Lead] results in decreased activity of ALAD protein CTD PMID:2748540 NCBI chr 9:113,386,312...113,401,284
Ensembl chr 9:113,386,312...113,401,290
JBrowse link
G ALDH1A1 aldehyde dehydrogenase 1 family member A1 decreases activity
decreases expression
multiple interactions
ISO
EXP
Disulfiram results in decreased activity of ALDH1A1 protein
Disulfiram results in decreased expression of ALDH1A1 mRNA; Disulfiram results in decreased expression of ALDH1A1 protein
Disulfiram inhibits the reaction [ALDH1A1 protein results in decreased susceptibility to maphosphamide]
CTD PMID:8562935 PMID:10998257 PMID:21035945 PMID:34242567 NCBI chr 9:72,900,671...72,953,053
Ensembl chr 9:72,900,671...73,080,442
JBrowse link
G ALDH1A2 aldehyde dehydrogenase 1 family member A2 decreases activity EXP Disulfiram results in decreased activity of ALDH1A2 protein CTD PMID:22079344 NCBI chr15:57,953,429...58,065,711
Ensembl chr15:57,953,424...58,497,866
JBrowse link
G ALDH2 aldehyde dehydrogenase 2 family member decreases activity
decreases expression
multiple interactions
ISO
EXP
Disulfiram metabolite results in decreased activity of ALDH2 protein; Disulfiram results in decreased activity of ALDH2 protein
Disulfiram results in decreased expression of ALDH2 mRNA
[Disulfiram results in decreased activity of ALDH2 protein] which results in increased susceptibility to Glyceraldehyde; [Disulfiram results in decreased activity of ALDH2 protein] which results in increased susceptibility to glycolaldehyde; [Disulfiram results in decreased activity of ALDH2 protein] which results in increased susceptibility to Glyoxal; [Disulfiram results in decreased activity of ALDH2 protein] which results in increased susceptibility to hydroxypyruvic acid; [Disulfiram results in decreased activity of ALDH2 protein] which results in increased susceptibility to Pyruvaldehyde
CTD PMID:9585485 PMID:10513990 PMID:11142365 PMID:21334317 PMID:21376711 More... NCBI chr12:111,766,933...111,817,532
Ensembl chr12:111,766,887...111,817,532
JBrowse link
G ALDH3A1 aldehyde dehydrogenase 3 family member A1 increases metabolic processing EXP ALDH3A1 protein results in increased metabolism of Disulfiram CTD PMID:18591790 NCBI chr17:19,737,984...19,748,298
Ensembl chr17:19,737,984...19,748,943
JBrowse link
G ANGPTL4 angiopoietin like 4 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of ANGPTL4 mRNA CTD PMID:24690739 NCBI chr19:8,364,155...8,374,370
Ensembl chr19:8,363,289...8,374,370
JBrowse link
G ANO6 anoctamin 6 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of ANO6 mRNA CTD PMID:24690739 NCBI chr12:45,216,095...45,440,404
Ensembl chr12:45,215,987...45,482,280
JBrowse link
G APAF1 apoptotic peptidase activating factor 1 increases expression EXP Disulfiram results in increased expression of APAF1 mRNA CTD PMID:34182011 NCBI chr12:98,645,290...98,735,433
Ensembl chr12:98,645,149...98,735,433
JBrowse link
G APBB3 amyloid beta precursor protein binding family B member 3 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of APBB3 mRNA CTD PMID:24690739 NCBI chr 5:140,558,268...140,564,598
Ensembl chr 5:140,558,268...140,564,781
JBrowse link
G APCDD1L APC down-regulated 1 like multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of APCDD1L mRNA CTD PMID:24690739 NCBI chr20:58,459,101...58,515,399
Ensembl chr20:58,459,101...58,515,399
JBrowse link
G APP amyloid beta precursor protein multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of APP mRNA CTD PMID:24690739 NCBI chr21:25,880,550...26,171,128
Ensembl chr21:25,880,535...26,171,128
JBrowse link
G AR androgen receptor multiple interactions EXP [Disulfiram co-treated with cupric chloride] results in decreased expression of AR protein; Disulfiram inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein] CTD PMID:19789329 PMID:33049310 NCBI chr  X:67,544,021...67,730,619
Ensembl chr  X:67,544,021...67,730,619
JBrowse link
G ARC activity regulated cytoskeleton associated protein multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of ARC mRNA CTD PMID:24690739 NCBI chr 8:142,611,049...142,614,479
Ensembl chr 8:142,611,049...142,614,479
JBrowse link
G ASGR1 asialoglycoprotein receptor 1 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of ASGR1 mRNA CTD PMID:24690739 NCBI chr17:7,173,431...7,179,370
Ensembl chr17:7,173,431...7,179,564
JBrowse link
G ASMTL acetylserotonin O-methyltransferase like multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of ASMTL mRNA CTD PMID:24690739 NCBI chr  X:1,403,139...1,453,756
NCBI chr  Y:1,403,139...1,453,756
Ensembl chr  Y:1,403,139...1,453,762
Ensembl chr  X:1,403,139...1,453,762
JBrowse link
G ASNS asparagine synthetase (glutamine-hydrolyzing) multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of ASNS mRNA CTD PMID:24690739 NCBI chr 7:97,851,677...97,928,441
Ensembl chr 7:97,851,677...97,872,542
JBrowse link
G ATF1 activating transcription factor 1 multiple interactions EXP [Disulfiram co-treated with Copper] results in decreased activity of ATF1 protein; Copper promotes the reaction [Disulfiram results in decreased activity of ATF1 protein] CTD PMID:15367699 NCBI chr12:50,763,459...50,821,162
Ensembl chr12:50,763,710...50,821,162
JBrowse link
G ATF2 activating transcription factor 2 multiple interactions EXP [Disulfiram co-treated with Copper] results in decreased activity of ATF2 protein; Copper promotes the reaction [Disulfiram results in decreased activity of ATF2 protein] CTD PMID:15367699 NCBI chr 2:175,072,259...175,168,203
Ensembl chr 2:175,072,250...175,168,382
JBrowse link
G ATF3 activating transcription factor 3 multiple interactions
increases expression
EXP [Disulfiram binds to Copper] which results in decreased expression of ATF3 mRNA; MTF1 protein affects the reaction [Disulfiram results in increased expression of ATF3 mRNA] CTD PMID:24690739 PMID:32661532 NCBI chr 1:212,565,407...212,620,777
Ensembl chr 1:212,565,334...212,620,777
JBrowse link
G ATG101 autophagy related 101 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of ATG101 mRNA CTD PMID:24690739 NCBI chr12:52,065,300...52,077,495
Ensembl chr12:52,069,246...52,077,495
JBrowse link
G ATP2B1 ATPase plasma membrane Ca2+ transporting 1 decreases expression ISO Disulfiram results in decreased expression of ATP2B1 mRNA CTD PMID:15003327 NCBI chr12:89,588,049...89,709,366
Ensembl chr12:89,588,049...89,709,366
JBrowse link
G ATP5MK ATP synthase membrane subunit k multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of ATP5MK mRNA CTD PMID:24690739 NCBI chr10:103,389,050...103,396,475
Ensembl chr10:103,389,041...103,396,492
JBrowse link
G ATP6V0D1 ATPase H+ transporting V0 subunit d1 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of ATP6V0D1 mRNA CTD PMID:24690739 NCBI chr16:67,438,019...67,481,157
Ensembl chr16:67,438,014...67,481,181
JBrowse link
G ATP6V1G1 ATPase H+ transporting V1 subunit G1 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of ATP6V1G1 mRNA CTD PMID:24690739 NCBI chr 9:114,587,769...114,598,879
Ensembl chr 9:114,587,706...114,598,915
JBrowse link
G ATXN1L ataxin 1 like multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of ATXN1L mRNA CTD PMID:24690739 NCBI chr16:71,845,976...71,857,328
Ensembl chr16:71,808,439...71,885,268
JBrowse link
G ATXN3 ataxin 3 affects localization
increases response to substance
EXP Disulfiram affects the localization of ATXN3 protein alternative form
ATXN3 protein alternative form results in increased susceptibility to Disulfiram
CTD PMID:31378764 NCBI chr14:92,044,775...92,106,582
Ensembl chr14:92,044,496...92,106,621
JBrowse link
G BAD BCL2 associated agonist of cell death increases expression EXP Disulfiram results in increased expression of BAD mRNA CTD PMID:34182011 NCBI chr11:64,269,828...64,284,704
Ensembl chr11:64,269,830...64,284,704
JBrowse link
G BAG3 BAG cochaperone 3 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of BAG3 mRNA CTD PMID:24690739 NCBI chr10:119,651,380...119,677,819
Ensembl chr10:119,651,380...119,677,819
JBrowse link
G BAK1 BCL2 antagonist/killer 1 multiple interactions EXP [arsenic trioxide co-treated with Ascorbic Acid co-treated with Disulfiram] results in decreased expression of BAK1 protein CTD PMID:24126434 NCBI chr 6:33,572,552...33,580,276
Ensembl chr 6:33,572,547...33,580,293
JBrowse link
G BAX BCL2 associated X, apoptosis regulator increases expression
multiple interactions
EXP Disulfiram results in increased expression of BAX mRNA; Disulfiram results in increased expression of BAX protein
[arsenic trioxide co-treated with Ascorbic Acid co-treated with Disulfiram] results in increased expression of BAX protein; [Copper co-treated with Disulfiram] results in increased expression of BAX protein
CTD PMID:17079463 PMID:23033007 PMID:24126434 PMID:34182011 NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798
JBrowse link
G BBC3 BCL2 binding component 3 increases expression EXP Disulfiram results in increased expression of BBC3 mRNA CTD PMID:34182011 NCBI chr19:47,220,824...47,232,860
Ensembl chr19:47,220,822...47,232,766
JBrowse link
G BBS2 Bardet-Biedl syndrome 2 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of BBS2 mRNA CTD PMID:24690739 NCBI chr16:56,470,403...56,520,024
Ensembl chr16:56,465,640...56,582,667
JBrowse link
G BCCIP BRCA2 and CDKN1A interacting protein multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of BCCIP mRNA CTD PMID:24690739 NCBI chr10:125,823,546...125,853,695
Ensembl chr10:125,823,546...125,853,695
JBrowse link
G BCL2 BCL2 apoptosis regulator multiple interactions
decreases expression
EXP [arsenic trioxide co-treated with Ascorbic Acid co-treated with Disulfiram] results in decreased expression of BCL2 protein; [Copper co-treated with Disulfiram] results in decreased expression of BCL2 protein; [Disulfiram co-treated with cupric chloride] results in decreased expression of BCL2 protein
Disulfiram results in decreased expression of BCL2 mRNA
CTD PMID:21911303 PMID:23033007 PMID:24126434 PMID:34182011 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128
JBrowse link
G BCL2L1 BCL2 like 1 decreases expression EXP Disulfiram results in decreased expression of BCL2L1 mRNA CTD PMID:34182011 NCBI chr20:31,664,452...31,723,963
Ensembl chr20:31,664,452...31,723,989
JBrowse link
G BCL2L11 BCL2 like 11 increases expression EXP Disulfiram results in increased expression of BCL2L11 mRNA CTD PMID:34182011 NCBI chr 2:111,120,914...111,168,445
Ensembl chr 2:111,119,378...111,168,444
JBrowse link
G BDNF brain derived neurotrophic factor multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of BDNF mRNA CTD PMID:24690739 NCBI chr11:27,654,893...27,722,030
Ensembl chr11:27,654,893...27,722,058
JBrowse link
G BECN1 beclin 1 increases expression EXP Disulfiram results in increased expression of BECN1 mRNA CTD PMID:34182011 NCBI chr17:42,810,132...42,824,282
Ensembl chr17:42,810,134...42,833,350
JBrowse link
G BGLAP bone gamma-carboxyglutamate protein increases expression ISO Disulfiram results in increased expression of BGLAP mRNA CTD PMID:24496638 NCBI chr 1:156,242,184...156,243,317
Ensembl chr 1:156,242,184...156,243,317
JBrowse link
G BIRC5 baculoviral IAP repeat containing 5 increases expression EXP Disulfiram results in increased expression of BIRC5 protein CTD PMID:34182011 NCBI chr17:78,214,253...78,225,635
Ensembl chr17:78,214,186...78,225,636
JBrowse link
G BMP7 bone morphogenetic protein 7 multiple interactions ISO Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of BMP7 mRNA] CTD PMID:22285649 NCBI chr20:57,168,753...57,266,641
Ensembl chr20:57,168,753...57,266,641
JBrowse link
G BNIP3 BCL2 interacting protein 3 increases expression EXP Disulfiram results in increased expression of BNIP3 mRNA CTD PMID:34182011 NCBI chr10:131,967,684...131,981,923
Ensembl chr10:131,967,684...131,981,967
JBrowse link
G BRF2 BRF2 general transcription factor IIIB subunit multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of BRF2 mRNA CTD PMID:24690739 NCBI chr 8:37,843,268...37,849,861
Ensembl chr 8:37,843,268...37,849,861
JBrowse link
G BTK Bruton tyrosine kinase multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of BTK mRNA CTD PMID:24690739 NCBI chr  X:101,349,450...101,390,796
Ensembl chr  X:101,349,338...101,390,796
JBrowse link
G BTN3A2 butyrophilin subfamily 3 member A2 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of BTN3A2 mRNA CTD PMID:24690739 NCBI chr 6:26,365,169...26,378,320
Ensembl chr 6:26,365,159...26,378,320
JBrowse link
G C11orf96 chromosome 11 open reading frame 96 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of C11ORF96 mRNA CTD PMID:24690739 NCBI chr11:43,942,637...43,943,878
Ensembl chr11:43,942,637...43,943,878
JBrowse link
G C1R complement C1r multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of C1R mRNA CTD PMID:24690739 NCBI chr12:7,080,219...7,092,445
Ensembl chr12:7,080,214...7,092,540
JBrowse link
G C1S complement C1s multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of C1S mRNA CTD PMID:24690739 NCBI chr12:7,060,718...7,071,032
Ensembl chr12:6,988,259...7,071,032
JBrowse link
G C2orf42 chromosome 2 open reading frame 42 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of C2ORF42 mRNA CTD PMID:24690739 NCBI chr 2:70,149,885...70,191,019
Ensembl chr 2:70,149,885...70,248,615
JBrowse link
G C2orf49 chromosome 2 open reading frame 49 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of C2ORF49 mRNA CTD PMID:24690739 NCBI chr 2:105,337,540...105,385,899
Ensembl chr 2:105,337,532...105,350,712
JBrowse link
G C3orf52 chromosome 3 open reading frame 52 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of C3ORF52 mRNA CTD PMID:24690739 NCBI chr 3:112,086,389...112,136,381
Ensembl chr 3:112,086,335...112,131,004
JBrowse link
G CA2 carbonic anhydrase 2 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of CA2 mRNA CTD PMID:24690739 NCBI chr 8:85,464,007...85,481,493
Ensembl chr 8:85,463,968...85,481,493
JBrowse link
G CA7 carbonic anhydrase 7 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of CA7 mRNA CTD PMID:24690739 NCBI chr16:66,844,414...66,854,147
Ensembl chr16:66,844,414...66,854,153
JBrowse link
G CACYBP calcyclin binding protein multiple interactions
increases expression
EXP [Disulfiram binds to Copper] which results in decreased expression of CACYBP mRNA
Disulfiram results in increased expression of CACYBP mRNA; Disulfiram results in increased expression of CACYBP protein
CTD PMID:24690739 PMID:34182011 NCBI chr 1:174,999,435...175,012,027
Ensembl chr 1:174,999,163...175,012,027
JBrowse link
G CALCB calcitonin related polypeptide beta multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of CALCB mRNA CTD PMID:24690739 NCBI chr11:15,073,593...15,078,637
Ensembl chr11:14,904,997...15,082,342
JBrowse link
G CALD1 caldesmon 1 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of CALD1 mRNA CTD PMID:24690739 NCBI chr 7:134,745,467...134,970,729
Ensembl chr 7:134,744,252...134,970,729
JBrowse link
G CALM1 calmodulin 1 decreases expression EXP Disulfiram results in decreased expression of CALM1 mRNA CTD PMID:34182011 NCBI chr14:90,396,502...90,408,268
Ensembl chr14:90,396,502...90,408,268
JBrowse link
G CALM2 calmodulin 2 increases expression EXP Disulfiram results in increased expression of CALM2 mRNA CTD PMID:34182011 NCBI chr 2:47,160,082...47,176,936
Ensembl chr 2:47,160,084...47,176,921
JBrowse link
G CALM3 calmodulin 3 decreases expression EXP Disulfiram results in decreased expression of CALM3 mRNA CTD PMID:34182011 NCBI chr19:46,601,074...46,610,782
Ensembl chr19:46,601,074...46,610,782
JBrowse link
G CASP3 caspase 3 multiple interactions
increases activity
ISO
EXP
[Disulfiram binds to cupric chloride] which results in increased activity of CASP3 protein; bathocuproine sulfonate inhibits the reaction [[Disulfiram binds to cupric chloride] which results in increased activity of CASP3 protein]
[Disulfiram binds to Copper] which results in increased activity of CASP3 protein; Disulfiram promotes the reaction [Carmustine results in increased cleavage of CASP3 protein]
Disulfiram results in increased activity of CASP3 protein
CTD PMID:11239917 PMID:17026967 PMID:17079463 PMID:24193513 PMID:24690739 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062
JBrowse link
G CASP7 caspase 7 increases activity EXP Disulfiram results in increased activity of CASP7 protein CTD PMID:17026967 NCBI chr10:113,679,194...113,730,909
Ensembl chr10:113,679,162...113,730,907
JBrowse link
G CASP9 caspase 9 multiple interactions
increases expression
EXP [Disulfiram binds to Copper] which results in increased activity of CASP9 protein
Disulfiram results in increased expression of CASP9 mRNA
CTD PMID:24690739 PMID:34182011 NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534
JBrowse link
G CAT catalase increases expression
multiple interactions
decreases expression
EXP Disulfiram results in increased expression of CAT mRNA
Zinc Sulfate inhibits the reaction [Disulfiram results in decreased expression of CAT mRNA]
CTD PMID:20566472 PMID:32712770 PMID:34182011 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060
JBrowse link
G CCAR1 cell division cycle and apoptosis regulator 1 multiple interactions ISO
EXP
[Disulfiram binds to Copper] which results in increased expression of CCAR1 protein CTD PMID:24690739 NCBI chr10:68,721,239...68,792,377
Ensembl chr10:68,721,012...68,792,377
JBrowse link
G CCDC59 coiled-coil domain containing 59 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of CCDC59 mRNA CTD PMID:24690739 NCBI chr12:82,352,303...82,358,805
Ensembl chr12:82,223,681...82,358,805
JBrowse link
G CCDC92 coiled-coil domain containing 92 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of CCDC92 mRNA CTD PMID:24690739 NCBI chr12:123,935,626...123,972,831
Ensembl chr12:123,918,660...123,972,831
JBrowse link
G CCK cholecystokinin decreases expression
multiple interactions
ISO
EXP
Disulfiram results in decreased expression of CCK protein alternative form
[Disulfiram binds to Copper] which results in decreased expression of CCK mRNA
CTD PMID:8246921 PMID:24690739 NCBI chr 3:42,257,826...42,266,185
Ensembl chr 3:42,257,825...42,266,185
JBrowse link
G CCL2 C-C motif chemokine ligand 2 multiple interactions
decreases secretion
EXP [Disulfiram binds to Copper] which results in increased expression of CCL2 mRNA; [Zinc Sulfate co-treated with Disulfiram] inhibits the reaction [Lipopolysaccharides results in increased secretion of CCL2 protein]; Disulfiram inhibits the reaction [Lipopolysaccharides results in increased secretion of CCL2 protein]
Disulfiram results in decreased secretion of CCL2 protein
CTD PMID:24690739 PMID:32712770 NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208
JBrowse link
G CCL26 C-C motif chemokine ligand 26 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of CCL26 mRNA CTD PMID:24690739 NCBI chr 7:75,769,524...75,791,597
Ensembl chr 7:75,769,533...75,789,896
JBrowse link
G CCL5 C-C motif chemokine ligand 5 multiple interactions ISO
EXP
Disulfiram inhibits the reaction [[CCL5 protein binds to and results in increased activity of CCR5 protein] which results in increased abundance of Nitric Oxide]; Disulfiram inhibits the reaction [[CCL5 protein binds to and results in increased activity of CCR5 protein] which results in increased abundance of Reactive Oxygen Species]; Disulfiram inhibits the reaction [[CCL5 protein binds to and results in increased activity of CCR5 protein] which results in increased secretion of TNF protein]
[Disulfiram binds to Copper] which results in increased expression of CCL5 mRNA
CTD PMID:19016906 PMID:24690739 NCBI chr17:35,871,491...35,880,360
Ensembl chr17:35,871,491...35,880,793
JBrowse link
G CCNA2 cyclin A2 multiple interactions
decreases expression
EXP [Disulfiram co-treated with Copper] results in decreased expression of CCNA2 protein
Disulfiram results in decreased expression of CCNA2 mRNA
CTD PMID:15367699 PMID:34182011 NCBI chr 4:121,816,444...121,823,883
Ensembl chr 4:121,816,444...121,823,883
JBrowse link
G CCND1 cyclin D1 decreases expression EXP Disulfiram results in decreased expression of CCND1 mRNA CTD PMID:34182011 NCBI chr11:69,641,156...69,654,474
Ensembl chr11:69,641,156...69,654,474
JBrowse link
G CCND2 cyclin D2 multiple interactions ISO Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of CCND2 mRNA] CTD PMID:22285649 NCBI chr12:4,273,762...4,305,353
Ensembl chr12:4,269,771...4,305,353
JBrowse link
G CCNK cyclin K multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of CCNK mRNA CTD PMID:24690739 NCBI chr14:99,481,409...99,512,440
Ensembl chr14:99,481,169...99,535,044
JBrowse link
G CCPG1 cell cycle progression 1 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of CCPG1 mRNA CTD PMID:24690739 NCBI chr15:55,355,239...55,408,359
Ensembl chr15:55,340,032...55,408,510
JBrowse link
G CCR2 C-C motif chemokine receptor 2 increases expression EXP Disulfiram results in increased expression of CCR2 protein CTD PMID:32712770 NCBI chr 3:46,354,111...46,360,940
Ensembl chr 3:46,353,864...46,360,940
JBrowse link
G CCR5 C-C motif chemokine receptor 5 multiple interactions ISO Disulfiram inhibits the reaction [[CCL5 protein binds to and results in increased activity of CCR5 protein] which results in increased abundance of Nitric Oxide]; Disulfiram inhibits the reaction [[CCL5 protein binds to and results in increased activity of CCR5 protein] which results in increased abundance of Reactive Oxygen Species]; Disulfiram inhibits the reaction [[CCL5 protein binds to and results in increased activity of CCR5 protein] which results in increased secretion of TNF protein] CTD PMID:19016906 NCBI chr 3:46,370,142...46,376,206
Ensembl chr 3:46,370,946...46,376,206
JBrowse link
G CD163 CD163 molecule multiple interactions
decreases expression
EXP [Zinc Sulfate co-treated with Disulfiram] results in decreased expression of CD163 mRNA
Disulfiram results in decreased expression of CD163 mRNA
CTD PMID:32712770 NCBI chr12:7,470,811...7,503,777
Ensembl chr12:7,470,811...7,503,893
JBrowse link
G CD36 CD36 molecule (CD36 blood group) multiple interactions
decreases expression
EXP [Zinc Sulfate co-treated with Disulfiram] results in decreased expression of CD36 mRNA
Disulfiram results in decreased expression of CD36 mRNA
CTD PMID:32712770 NCBI chr 7:80,602,207...80,679,274
Ensembl chr 7:80,369,575...80,679,277
JBrowse link
G CD46 CD46 molecule multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of CD46 mRNA CTD PMID:24690739 NCBI chr 1:207,752,038...207,795,516
Ensembl chr 1:207,752,037...207,795,513
JBrowse link
G CD47 CD47 molecule multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of CD47 mRNA CTD PMID:24690739 NCBI chr 3:108,043,091...108,091,031
Ensembl chr 3:108,043,091...108,091,862
JBrowse link
G CD9 CD9 molecule multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of CD9 mRNA CTD PMID:24690739 NCBI chr12:6,199,946...6,238,266
Ensembl chr12:6,199,715...6,238,271
JBrowse link
G CDC42EP5 CDC42 effector protein 5 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of CDC42EP5 mRNA CTD PMID:24690739 NCBI chr19:54,465,026...54,473,296
Ensembl chr19:54,465,026...54,473,296
JBrowse link
G CDH11 cadherin 11 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of CDH11 mRNA CTD PMID:24690739 NCBI chr16:64,943,753...65,123,744
Ensembl chr16:64,943,753...65,126,112
JBrowse link
G CDH2 cadherin 2 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of CDH2 mRNA CTD PMID:24690739 NCBI chr18:27,932,879...28,177,130
Ensembl chr18:27,932,879...28,177,946
JBrowse link
G CDK2 cyclin dependent kinase 2 decreases expression EXP Disulfiram results in decreased expression of CDK2 mRNA CTD PMID:34182011 NCBI chr12:55,966,830...55,972,789
Ensembl chr12:55,966,781...55,972,789
JBrowse link
G CDK4 cyclin dependent kinase 4 decreases expression EXP Disulfiram results in decreased expression of CDK4 mRNA CTD PMID:34182011 NCBI chr12:57,747,727...57,752,310
Ensembl chr12:57,747,727...57,756,013
JBrowse link
G CDK5R1 cyclin dependent kinase 5 regulatory subunit 1 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of CDK5R1 mRNA CTD PMID:24690739 NCBI chr17:32,486,993...32,491,253
Ensembl chr17:32,486,993...32,491,253
JBrowse link
G CDK5RAP3 CDK5 regulatory subunit associated protein 3 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of CDK5RAP3 mRNA CTD PMID:24690739 NCBI chr17:47,967,904...47,981,781
Ensembl chr17:47,967,810...47,981,781
JBrowse link
G CDK6 cyclin dependent kinase 6 decreases expression EXP Disulfiram results in decreased expression of CDK6 mRNA CTD PMID:34182011 NCBI chr 7:92,604,921...92,836,573
Ensembl chr 7:92,604,921...92,836,573
JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A increases expression EXP Disulfiram results in increased expression of CDKN1A mRNA CTD PMID:34182011 NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,397
JBrowse link
G CDKN1B cyclin dependent kinase inhibitor 1B increases expression
multiple interactions
EXP
ISO
Disulfiram results in increased expression of CDKN1B mRNA; Disulfiram results in increased expression of CDKN1B protein
[Disulfiram binds to Copper] which results in increased expression of CDKN1B protein
CTD PMID:17079463 PMID:24690739 PMID:34182011 NCBI chr12:12,717,368...12,722,369
Ensembl chr12:12,685,498...12,722,369
JBrowse link
G CDKN1C cyclin dependent kinase inhibitor 1C multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of CDKN1C mRNA CTD PMID:24690739 NCBI chr11:2,883,218...2,885,775
Ensembl chr11:2,883,213...2,885,775
JBrowse link
G CDKN2AIP CDKN2A interacting protein multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of CDKN2AIP mRNA CTD PMID:24690739 NCBI chr 4:183,444,636...183,449,064
Ensembl chr 4:183,444,635...183,449,064
JBrowse link
G CDKN2B cyclin dependent kinase inhibitor 2B increases expression EXP Disulfiram results in increased expression of CDKN2B mRNA CTD PMID:34182011 NCBI chr 9:22,002,903...22,009,313
Ensembl chr 9:22,002,903...22,009,305
JBrowse link
G CEMIP cell migration inducing hyaluronidase 1 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of CEMIP mRNA CTD PMID:24690739 NCBI chr15:80,779,370...80,951,771
Ensembl chr15:80,779,343...80,951,776
JBrowse link
G CENPW centromere protein W multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of CENPW mRNA CTD PMID:24690739 NCBI chr 6:126,340,115...126,483,320
Ensembl chr 6:126,340,115...126,348,875
JBrowse link
G CFAP53 cilia and flagella associated protein 53 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of CFAP53 mRNA CTD PMID:24690739 NCBI chr18:50,227,193...50,266,495
Ensembl chr18:50,227,193...50,266,495
JBrowse link
G CFB complement factor B multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of CFB mRNA CTD PMID:24690739 NCBI chr 6:31,946,095...31,952,084
Ensembl chr 6:31,945,650...31,952,086
JBrowse link
G CFL1 cofilin 1 increases expression EXP Disulfiram results in increased expression of CFL1 protein CTD PMID:34182011 NCBI chr11:65,854,673...65,858,180
Ensembl chr11:65,823,022...65,862,026
JBrowse link
G CHGA chromogranin A multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of CHGA mRNA CTD PMID:24690739 NCBI chr14:92,922,664...92,935,285
Ensembl chr14:92,923,150...92,935,285
JBrowse link
G CHMP1B charged multivesicular body protein 1B multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of CHMP1B mRNA CTD PMID:24690739 NCBI chr18:11,851,413...11,854,444
Ensembl chr18:11,851,413...11,854,444
JBrowse link
G CHORDC1 cysteine and histidine rich domain containing 1 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of CHORDC1 mRNA CTD PMID:24690739 NCBI chr11:90,200,429...90,223,049
Ensembl chr11:90,200,429...90,223,077
JBrowse link
G CIDECP1 CIDEC pseudogene 1 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of CIDECP1 mRNA CTD PMID:24690739 NCBI chr 3:10,017,553...10,026,136
Ensembl chr 3:10,017,490...10,023,747
JBrowse link
G CILP cartilage intermediate layer protein multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of CILP mRNA CTD PMID:24690739 NCBI chr15:65,194,760...65,211,473
Ensembl chr15:65,194,760...65,211,473
JBrowse link
G CIRBP cold inducible RNA binding protein multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of CIRBP mRNA CTD PMID:24690739 NCBI chr19:1,269,332...1,274,880
Ensembl chr19:1,259,384...1,274,880
JBrowse link
G CKAP4 cytoskeleton associated protein 4 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of CKAP4 mRNA CTD PMID:24690739 NCBI chr12:106,237,881...106,248,020
Ensembl chr12:106,237,881...106,304,279
JBrowse link
G CLDN1 claudin 1 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of CLDN1 mRNA CTD PMID:24690739 NCBI chr 3:190,305,707...190,322,446
Ensembl chr 3:190,305,707...190,322,446
JBrowse link
G CLEC7A C-type lectin domain containing 7A increases expression EXP Disulfiram results in increased expression of CLEC7A protein CTD PMID:32712770 NCBI chr12:10,116,777...10,130,304
Ensembl chr12:10,116,777...10,130,258
JBrowse link
G CLP1 cleavage factor polyribonucleotide kinase subunit 1 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of CLP1 mRNA CTD PMID:24690739 NCBI chr11:57,657,762...57,661,865
Ensembl chr11:57,648,188...57,661,865
JBrowse link
G CLTA clathrin light chain A multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of CLTA mRNA CTD PMID:24690739 NCBI chr 9:36,190,874...36,212,059
Ensembl chr 9:36,190,856...36,304,781
JBrowse link
G CMKLR2 chemerin chemokine-like receptor 2 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of CMKLR2 mRNA CTD PMID:24690739 NCBI chr 2:206,175,316...206,217,912
Ensembl chr 2:206,175,316...206,218,047
JBrowse link
G CNTNAP1 contactin associated protein 1 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of CNTNAP1 mRNA CTD PMID:24690739 NCBI chr17:42,682,531...42,699,993
Ensembl chr17:42,682,531...42,699,993
JBrowse link
G COL12A1 collagen type XII alpha 1 chain multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of COL12A1 mRNA CTD PMID:24690739 NCBI chr 6:75,084,326...75,206,053
Ensembl chr 6:75,084,326...75,206,267
JBrowse link
G COL1A1 collagen type I alpha 1 chain decreases expression EXP Disulfiram results in decreased expression of COL1A1 protein CTD PMID:34182011 NCBI chr17:50,184,101...50,201,631
Ensembl chr17:50,184,101...50,201,632
JBrowse link
G COL1A2 collagen type I alpha 2 chain multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of COL1A2 mRNA CTD PMID:24690739 NCBI chr 7:94,394,895...94,431,227
Ensembl chr 7:94,394,895...94,431,227
JBrowse link
G COL3A1 collagen type III alpha 1 chain multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of COL3A1 mRNA CTD PMID:24690739 NCBI chr 2:188,974,373...189,012,746
Ensembl chr 2:188,974,373...189,012,746
JBrowse link
G COL4A1 collagen type IV alpha 1 chain multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of COL4A1 mRNA CTD PMID:24690739 NCBI chr13:110,148,963...110,307,157
Ensembl chr13:110,148,963...110,307,202
JBrowse link
G COL5A1 collagen type V alpha 1 chain multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of COL5A1 mRNA CTD PMID:24690739 NCBI chr 9:134,641,803...134,844,843
Ensembl chr 9:134,641,803...134,844,843
JBrowse link
G COMMD9 COMM domain containing 9 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of COMMD9 mRNA CTD PMID:24690739 NCBI chr11:36,272,292...36,289,424
Ensembl chr11:36,269,284...36,289,449
JBrowse link
G CRABP2 cellular retinoic acid binding protein 2 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of CRABP2 mRNA CTD PMID:24690739 NCBI chr 1:156,699,606...156,705,784
Ensembl chr 1:156,699,606...156,705,816
JBrowse link
G CREB1 cAMP responsive element binding protein 1 multiple interactions EXP [Disulfiram co-treated with Copper] results in decreased activity of CREB1 protein; Copper promotes the reaction [Disulfiram results in decreased activity of CREB1 protein] CTD PMID:15367699 NCBI chr 2:207,529,962...207,605,988
Ensembl chr 2:207,529,737...207,605,988
JBrowse link
G CRELD2 cysteine rich with EGF like domains 2 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of CRELD2 mRNA CTD PMID:24690739 NCBI chr22:49,918,634...49,927,537
Ensembl chr22:49,918,167...49,927,540
JBrowse link
G CRIM1 cysteine rich transmembrane BMP regulator 1 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of CRIM1 mRNA CTD PMID:24690739 NCBI chr 2:36,355,778...36,551,135
Ensembl chr 2:36,355,778...36,551,135
JBrowse link
G CRIPT CXXC repeat containing interactor of PDZ3 domain multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of CRIPT mRNA CTD PMID:24690739 NCBI chr 2:46,617,215...46,630,176
Ensembl chr 2:46,616,416...46,685,037
JBrowse link
G CRISPLD2 cysteine rich secretory protein LCCL domain containing 2 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of CRISPLD2 mRNA CTD PMID:24690739 NCBI chr16:84,819,985...84,909,508
Ensembl chr16:84,819,985...84,920,768
JBrowse link
G CRYAB crystallin alpha B multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of CRYAB mRNA CTD PMID:24690739 NCBI chr11:111,908,564...111,923,740
Ensembl chr11:111,908,564...111,923,722
JBrowse link
G CSE1L chromosome segregation 1 like multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of CSE1L mRNA CTD PMID:24690739 NCBI chr20:49,046,312...49,096,949
Ensembl chr20:49,046,246...49,096,960
JBrowse link
G CSNK1E casein kinase 1 epsilon multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of CSNK1E mRNA CTD PMID:24690739 NCBI chr22:38,290,691...38,318,084
Ensembl chr22:38,290,691...38,318,084
JBrowse link
G CSRNP1 cysteine and serine rich nuclear protein 1 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of AXUD1 mRNA CTD PMID:24690739 NCBI chr 3:39,141,855...39,154,641
Ensembl chr 3:39,141,855...39,154,562
JBrowse link
G CSRP2 cysteine and glycine rich protein 2 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of CSRP2 mRNA CTD PMID:24690739 NCBI chr12:76,858,709...76,879,019
Ensembl chr12:76,858,709...76,879,023
JBrowse link
G CST6 cystatin E/M multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of CST6 mRNA CTD PMID:24690739 NCBI chr11:66,012,008...66,013,505
Ensembl chr11:66,012,008...66,013,505
JBrowse link
G CT45A3 cancer/testis antigen family 45 member A3 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of CT45A3 mRNA CTD PMID:24690739 NCBI chr  X:135,760,044...135,768,191
Ensembl chr  X:135,759,846...135,768,191
JBrowse link
G CTH cystathionine gamma-lyase increases expression EXP Disulfiram results in increased expression of CTH protein CTD PMID:34242567 NCBI chr 1:70,411,268...70,439,851
Ensembl chr 1:70,411,218...70,439,851
JBrowse link
G CWC25 CWC25 spliceosome associated protein homolog multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of CWC25 mRNA CTD PMID:24690739 NCBI chr17:38,800,441...38,825,321
Ensembl chr17:38,800,441...38,825,355
JBrowse link
G CXCR4 C-X-C motif chemokine receptor 4 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of CXCR4 mRNA CTD PMID:24690739 NCBI chr 2:136,114,349...136,118,149
Ensembl chr 2:136,114,349...136,119,177
JBrowse link
G CYP17A1 cytochrome P450 family 17 subfamily A member 1 multiple interactions ISO Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of CYP17A1 mRNA] CTD PMID:22285649 NCBI chr10:102,830,531...102,837,413
Ensembl chr10:102,830,531...102,837,472
JBrowse link
G CYP19A1 cytochrome P450 family 19 subfamily A member 1 multiple interactions ISO Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of CYP19A1 mRNA] CTD PMID:22285649 NCBI chr15:51,208,057...51,338,596
Ensembl chr15:51,208,057...51,338,601
JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 decreases activity EXP Disulfiram results in decreased activity of CYP1A1 protein CTD PMID:33814510 NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536
JBrowse link
G CYP1B1 cytochrome P450 family 1 subfamily B member 1 decreases activity EXP Disulfiram results in decreased activity of CYP1B1 protein CTD PMID:33814510 NCBI chr 2:38,067,509...38,076,151
Ensembl chr 2:38,066,973...38,109,902
JBrowse link
G CYP2C18 cytochrome P450 family 2 subfamily C member 18 decreases expression
decreases activity
ISO Disulfiram results in decreased expression of CYP2C11 protein
Disulfiram results in decreased activity of CYP2C11 protein
CTD PMID:9393675 NCBI chr10:94,683,729...94,736,190
Ensembl chr10:94,683,729...94,736,190
JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 multiple interactions
decreases activity
decreases expression
EXP
ISO
[Disulfiram results in decreased activity of CYP2E1 protein] which affects the activity of Styrene; Disulfiram inhibits the reaction [[CYP2E1 protein results in increased metabolism of Chlorzoxazone] which results in increased chemical synthesis of 6-hydroxychlorzoxazone]; Disulfiram inhibits the reaction [CYP2E1 protein results in increased chemical synthesis of 6-hydroxychlorzoxazone]; Disulfiram inhibits the reaction [CYP2E1 protein results in increased metabolism of Chlorzoxazone]; Disulfiram inhibits the reaction [CYP2E1 protein results in increased oxidation of Halothane]
Disulfiram results in decreased expression of CYP2E1 mRNA; Disulfiram results in decreased expression of CYP2E1 protein
Disulfiram binds to and results in decreased activity of CYP2E1 protein
CTD PMID:1664256 PMID:8637342 PMID:9393675 PMID:10805064 PMID:18754103 More... NCBI chr10:133,527,363...133,539,123
Ensembl chr10:133,520,406...133,561,220
JBrowse link
G CYP2R1 cytochrome P450 family 2 subfamily R member 1 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of CYP2R1 mRNA CTD PMID:24690739 NCBI chr11:14,877,440...14,892,443
Ensembl chr11:14,877,440...14,892,231
JBrowse link
G CYP3A4 cytochrome P450 family 3 subfamily A member 4 increases response to substance
decreases expression
decreases activity
EXP
ISO
CYP3A4 protein results in increased susceptibility to Disulfiram
Disulfiram results in decreased expression of CYP3A2 mRNA
Disulfiram results in decreased activity of CYP3A2 protein
CTD PMID:9393675 PMID:21540358 NCBI chr 7:99,756,967...99,784,184
Ensembl chr 7:99,756,960...99,784,248
JBrowse link
G DAG1 dystroglycan 1 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of DAG1 mRNA CTD PMID:24690739 NCBI chr 3:49,468,948...49,535,615
Ensembl chr 3:49,468,713...49,535,618
JBrowse link
G DBH dopamine beta-hydroxylase decreases activity
affects response to substance
EXP
ISO
Disulfiram results in decreased activity of DBH protein
DBH gene SNP affects the susceptibility to Disulfiram
DBH gene polymorphism affects the susceptibility to Disulfiram
CTD PMID:90468 PMID:16163519 PMID:19462300 NCBI chr 9:133,636,363...133,659,329
Ensembl chr 9:133,636,363...133,659,329
JBrowse link
G DCAF13 DDB1 and CUL4 associated factor 13 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of DCAF13 mRNA CTD PMID:24690739 NCBI chr 8:103,415,386...103,443,453
Ensembl chr 8:103,414,714...103,443,453
JBrowse link
G DCXR dicarbonyl and L-xylulose reductase multiple interactions EXP [Disulfiram co-treated with NADP] binds to DCXR protein CTD PMID:25526675 NCBI chr17:82,035,858...82,037,697
Ensembl chr17:82,035,136...82,037,709
JBrowse link
G DDIT3 DNA damage inducible transcript 3 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of DDIT3 mRNA CTD PMID:24690739 NCBI chr12:57,516,588...57,520,517
Ensembl chr12:57,516,588...57,521,737
JBrowse link
G DDX39A DExD-box helicase 39A multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of DDX39A mRNA CTD PMID:24690739 NCBI chr19:14,408,798...14,419,383
Ensembl chr19:14,408,798...14,419,383
JBrowse link
G DDX60 DExD/H-box helicase 60 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of DDX60 mRNA CTD PMID:24690739 NCBI chr 4:168,216,294...168,325,979
Ensembl chr 4:168,216,291...168,318,883
JBrowse link
G DEDD2 death effector domain containing 2 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of DEDD2 mRNA CTD PMID:24690739 NCBI chr19:42,198,598...42,220,134
Ensembl chr19:42,198,598...42,220,140
JBrowse link
G DEFB103B defensin beta 103B multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of DEFB103B mRNA CTD PMID:24690739 NCBI chr 8:7,428,888...7,430,348
Ensembl chr 8:7,881,392...7,882,663
Ensembl chr 8:7,881,392...7,882,663
JBrowse link
G DHDH dihydrodiol dehydrogenase multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of DHDH mRNA CTD PMID:24690739 NCBI chr19:48,932,795...48,944,969
Ensembl chr19:48,933,699...48,944,969
JBrowse link
G DHRS2 dehydrogenase/reductase 2 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of DHRS2 mRNA CTD PMID:24690739 NCBI chr14:23,630,115...23,645,639
Ensembl chr14:23,630,115...23,645,639
JBrowse link
G DHRS3 dehydrogenase/reductase 3 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of DHRS3 mRNA CTD PMID:24690739 NCBI chr 1:12,567,910...12,618,210
Ensembl chr 1:12,567,909...12,620,133
JBrowse link
G DKK3 dickkopf WNT signaling pathway inhibitor 3 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of DKK3 mRNA CTD PMID:24690739 NCBI chr11:11,963,036...12,009,745
Ensembl chr11:11,956,207...12,009,769
JBrowse link
G DLL1 delta like canonical Notch ligand 1 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of DLL1 mRNA CTD PMID:24690739 NCBI chr 6:170,282,206...170,291,078
Ensembl chr 6:170,282,206...170,306,565
JBrowse link
G DNAJA1 DnaJ heat shock protein family (Hsp40) member A1 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of DNAJA1 mRNA CTD PMID:24690739 NCBI chr 9:33,025,273...33,039,907
Ensembl chr 9:33,025,273...33,039,907
JBrowse link
G DNAJA4 DnaJ heat shock protein family (Hsp40) member A4 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of DNAJA4 mRNA CTD PMID:24690739 NCBI chr15:78,264,145...78,282,191
Ensembl chr15:78,264,086...78,282,196
JBrowse link
G DNAJB1 DnaJ heat shock protein family (Hsp40) member B1 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of DNAJB1 mRNA CTD PMID:24690739 NCBI chr19:14,514,769...14,560,391
Ensembl chr19:14,513,789...14,560,391
JBrowse link
G DNAJB6 DnaJ heat shock protein family (Hsp40) member B6 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of DNAJB6 mRNA CTD PMID:24690739 NCBI chr 7:157,337,004...157,417,439
Ensembl chr 7:157,335,381...157,417,439
JBrowse link
G DNAJC3 DnaJ heat shock protein family (Hsp40) member C3 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of DNAJC3 mRNA CTD PMID:24690739 NCBI chr13:95,677,139...95,794,988
Ensembl chr13:95,677,139...95,794,988
JBrowse link
G DPH3 diphthamide biosynthesis 3 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of DPH3 mRNA CTD PMID:24690739 NCBI chr 3:16,257,061...16,264,943
Ensembl chr 3:16,257,061...16,264,969
JBrowse link
G DRAM1 DNA damage regulated autophagy modulator 1 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of DRAM1 mRNA CTD PMID:24690739 NCBI chr12:101,877,580...101,923,612
Ensembl chr12:101,877,580...102,012,130
JBrowse link
G DSE dermatan sulfate epimerase multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of DSE mRNA CTD PMID:24690739 NCBI chr 6:116,254,171...116,444,861
Ensembl chr 6:116,254,173...116,444,861
JBrowse link
G DUSP2 dual specificity phosphatase 2 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of DUSP2 mRNA CTD PMID:24690739 NCBI chr 2:96,143,169...96,145,440
Ensembl chr 2:96,143,166...96,145,440
JBrowse link
G DUSP5 dual specificity phosphatase 5 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of DUSP5 mRNA CTD PMID:24690739 NCBI chr10:110,497,907...110,511,533
Ensembl chr10:110,497,907...110,511,533
JBrowse link
G DYNLL2 dynein light chain LC8-type 2 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of DYNLL2 mRNA CTD PMID:24690739 NCBI chr17:58,083,419...58,095,542
Ensembl chr17:58,083,419...58,095,542
JBrowse link
G EAF1 ELL associated factor 1 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of EAF1 mRNA CTD PMID:24690739 NCBI chr 3:15,427,598...15,442,613
Ensembl chr 3:15,427,598...15,450,635
JBrowse link
G EDIL3 EGF like repeats and discoidin domains 3 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of EDIL3 mRNA CTD PMID:24690739 NCBI chr 5:83,940,554...84,384,880
Ensembl chr 5:83,940,554...84,384,880
JBrowse link
G EED embryonic ectoderm development multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of EED mRNA CTD PMID:24690739 NCBI chr11:86,244,753...86,287,615
Ensembl chr11:86,201,212...86,279,807
JBrowse link
G EFEMP1 EGF containing fibulin extracellular matrix protein 1 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of EFEMP1 mRNA CTD PMID:24690739 NCBI chr 2:55,865,967...55,923,782
Ensembl chr 2:55,865,967...55,924,139
JBrowse link
G EGR1 early growth response 1 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of EGR1 mRNA CTD PMID:24690739 NCBI chr 5:138,465,479...138,469,303
Ensembl chr 5:138,465,479...138,469,303
JBrowse link
G EIF4A3 eukaryotic translation initiation factor 4A3 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of EIF4A3 mRNA CTD PMID:24690739 NCBI chr17:80,134,369...80,147,128
Ensembl chr17:80,134,369...80,147,151
JBrowse link
G ELL2 elongation factor for RNA polymerase II 2 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of ELL2 mRNA CTD PMID:24690739 NCBI chr 5:95,885,098...95,961,851
Ensembl chr 5:95,885,098...95,961,851
JBrowse link
G ELOF1 elongation factor 1 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of ELOF1 mRNA CTD PMID:24690739 NCBI chr19:11,553,046...11,559,230
Ensembl chr19:11,551,147...11,559,230
JBrowse link
G ESR1 estrogen receptor 1 multiple interactions EXP Disulfiram binds to and results in decreased activity of ESR1 protein CTD PMID:33049310 NCBI chr 6:151,656,672...152,129,619
Ensembl chr 6:151,656,691...152,129,619
JBrowse link
G ETS1 ETS proto-oncogene 1, transcription factor multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of ETS1 mRNA CTD PMID:24690739 NCBI chr11:128,458,765...128,587,558
Ensembl chr11:128,458,761...128,587,558
JBrowse link
G F12 coagulation factor XII multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of F12 mRNA CTD PMID:24690739 NCBI chr 5:177,402,141...177,409,564
Ensembl chr 5:177,402,133...177,416,583
JBrowse link
G FAM210A family with sequence similarity 210 member A multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of FAM210A mRNA CTD PMID:24690739 NCBI chr18:13,663,347...13,726,558
Ensembl chr18:13,663,347...13,726,663
JBrowse link
G FAM234A family with sequence similarity 234 member A multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of FAM234A mRNA CTD PMID:24690739 NCBI chr16:234,821...269,963
Ensembl chr16:234,521...272,183
JBrowse link
G FAM32A family with sequence similarity 32 member A multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of FAM32A mRNA CTD PMID:24690739 NCBI chr19:16,185,410...16,192,046
Ensembl chr19:16,185,380...16,192,046
JBrowse link
G FASLG Fas ligand increases expression EXP Disulfiram results in increased expression of FASLG mRNA CTD PMID:34182011 NCBI chr 1:172,659,103...172,666,876
Ensembl chr 1:172,659,103...172,666,876
JBrowse link
G FECH ferrochelatase increases expression EXP Disulfiram results in increased expression of FECH mRNA CTD PMID:20566472 NCBI chr18:57,544,377...57,586,702
Ensembl chr18:57,544,377...57,586,732
JBrowse link
G FKBP1A FKBP prolyl isomerase 1A multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of FKBP1A mRNA CTD PMID:24690739 NCBI chr20:1,368,978...1,393,054
Ensembl chr20:1,368,977...1,393,164
JBrowse link
G FLCN folliculin multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of FLCN mRNA CTD PMID:24690739 NCBI chr17:17,212,212...17,237,330
Ensembl chr17:17,212,212...17,237,188
JBrowse link
G FNDC11 fibronectin type III domain containing 11 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of FNDC11 mRNA CTD PMID:24690739 NCBI chr20:63,553,020...63,556,708
Ensembl chr20:63,547,891...63,556,695
JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of FOS mRNA CTD PMID:24690739 NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,283,190
JBrowse link
G FOSB FosB proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of FOSB mRNA CTD PMID:24690739 NCBI chr19:45,467,996...45,475,179
Ensembl chr19:45,467,995...45,475,179
JBrowse link
G FOXA3 forkhead box A3 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of FOXA3 mRNA CTD PMID:24690739 NCBI chr19:45,864,326...45,873,797
Ensembl chr19:45,863,989...45,873,797
JBrowse link
G FOXJ1 forkhead box J1 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of FOXJ1 mRNA CTD PMID:24690739 NCBI chr17:76,136,333...76,141,245
Ensembl chr17:76,136,333...76,141,245
JBrowse link
G FOXO1 forkhead box O1 increases expression EXP Disulfiram results in increased expression of FOXO1 mRNA CTD PMID:34182011 NCBI chr13:40,555,667...40,666,641
Ensembl chr13:40,555,667...40,666,641
JBrowse link
G FOXO3 forkhead box O3 increases expression EXP Disulfiram results in increased expression of FOXO3 mRNA CTD PMID:34182011 NCBI chr 6:108,559,825...108,684,774
Ensembl chr 6:108,559,835...108,684,774
JBrowse link
G FOXO4 forkhead box O4 increases expression EXP Disulfiram results in increased expression of FOXO4 mRNA CTD PMID:34182011 NCBI chr  X:71,095,851...71,103,532
Ensembl chr  X:71,095,851...71,103,535
JBrowse link
G FRG1 FSHD region gene 1 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of FRG1 mRNA CTD PMID:24690739 NCBI chr 4:189,940,872...189,963,192
Ensembl chr 4:189,940,855...189,963,202
JBrowse link
G FSHB follicle stimulating hormone subunit beta multiple interactions ISO Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of BMP7 mRNA]; Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of CCND2 mRNA]; Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of CYP17A1 mRNA]; Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of CYP19A1 mRNA]; Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of FSHR mRNA]; Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of LHCGR mRNA]; Tretinoin inhibits the reaction [Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of LHCGR mRNA]] CTD PMID:22285649 NCBI chr11:30,231,014...30,235,194
Ensembl chr11:30,231,014...30,235,261
JBrowse link
G FSHR follicle stimulating hormone receptor multiple interactions ISO Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of FSHR mRNA] CTD PMID:22285649 NCBI chr 2:48,962,157...49,154,515
Ensembl chr 2:48,962,157...49,154,527
JBrowse link
G FSTL1 follistatin like 1 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of FSTL1 mRNA CTD PMID:24690739 NCBI chr 3:120,392,293...120,450,992
Ensembl chr 3:120,392,293...120,451,016
JBrowse link
G FTCD formimidoyltransferase cyclodeaminase multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of FTCD mRNA CTD PMID:24690739 NCBI chr21:46,136,262...46,155,579
Ensembl chr21:46,136,160...46,155,579
JBrowse link
G FTH1P20 ferritin heavy chain 1 pseudogene 20 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of FTH1P20 mRNA CTD PMID:24690739 NCBI chr 2:180,872,705...180,873,565
Ensembl chr 2:180,872,867...180,873,414
JBrowse link
G FTL ferritin light chain increases expression EXP Disulfiram results in increased expression of FTL mRNA CTD PMID:20566472 NCBI chr19:48,965,309...48,966,879
Ensembl chr19:48,965,309...48,967,896
JBrowse link
G G6PD glucose-6-phosphate dehydrogenase increases expression EXP Disulfiram results in increased expression of G6PD mRNA CTD PMID:20566472 NCBI chr  X:154,531,390...154,547,569
Ensembl chr  X:154,517,825...154,547,572
JBrowse link
G GADD45A growth arrest and DNA damage inducible alpha increases expression EXP Disulfiram results in increased expression of GADD45A mRNA CTD PMID:34182011 NCBI chr 1:67,685,201...67,688,334
Ensembl chr 1:67,685,201...67,688,334
JBrowse link
G GADD45B growth arrest and DNA damage inducible beta multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of GADD45B mRNA CTD PMID:24690739 NCBI chr19:2,476,127...2,478,257
Ensembl chr19:2,476,122...2,478,805
JBrowse link
G GALNT10 polypeptide N-acetylgalactosaminyltransferase 10 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of GALNT10 mRNA CTD PMID:24690739 NCBI chr 5:154,190,733...154,420,984
Ensembl chr 5:154,190,730...154,420,984
JBrowse link
G GAS6 growth arrest specific 6 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of GAS6 mRNA CTD PMID:24690739 NCBI chr13:113,820,549...113,864,076
Ensembl chr13:113,820,549...113,864,076
JBrowse link
G GATA2 GATA binding protein 2 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of GATA2 mRNA CTD PMID:24690739 NCBI chr 3:128,479,422...128,493,201
Ensembl chr 3:128,479,427...128,493,201
JBrowse link
G GBP4 guanylate binding protein 4 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of GBP4 mRNA CTD PMID:24690739 NCBI chr 1:89,181,144...89,198,942
Ensembl chr 1:89,181,144...89,198,942
JBrowse link
G GCC1 GRIP and coiled-coil domain containing 1 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of GCC1 mRNA CTD PMID:24690739 NCBI chr 7:127,580,628...127,585,596
Ensembl chr 7:127,580,628...127,593,611
JBrowse link
G GCGR glucagon receptor multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of GCGR mRNA CTD PMID:24690739 NCBI chr17:81,804,150...81,814,008
Ensembl chr17:81,804,132...81,814,008
JBrowse link
G GCLC glutamate-cysteine ligase catalytic subunit increases expression EXP Disulfiram results in increased expression of GCLC mRNA CTD PMID:20566472 NCBI chr 6:53,497,341...53,545,101
Ensembl chr 6:53,497,341...53,616,970
JBrowse link
G GCLM glutamate-cysteine ligase modifier subunit increases expression EXP Disulfiram results in increased expression of GCLM mRNA CTD PMID:20566472 NCBI chr 1:93,885,199...93,909,430
Ensembl chr 1:93,885,199...93,909,456
JBrowse link
G GCNA germ cell nuclear acidic peptidase multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of GCNA mRNA CTD PMID:24690739 NCBI chr  X:71,578,437...71,613,583
Ensembl chr  X:71,578,437...71,613,583
JBrowse link
G GEM GTP binding protein overexpressed in skeletal muscle multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of GEM mRNA CTD PMID:24690739 NCBI chr 8:94,249,253...94,262,319
Ensembl chr 8:94,249,253...94,262,350
JBrowse link
G GEMIN6 gem nuclear organelle associated protein 6 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of GEMIN6 mRNA CTD PMID:24690739 NCBI chr 2:38,778,210...38,785,002
Ensembl chr 2:38,751,534...38,785,002
JBrowse link
G GH1 growth hormone 1 multiple interactions ISO GH1 protein inhibits the reaction [Disulfiram results in increased expression of CYP2B1 mRNA]; GH1 protein inhibits the reaction [Disulfiram results in increased expression of CYP2B2 mRNA] CTD PMID:8390837 NCBI chr17:63,917,203...63,918,839
Ensembl chr17:63,917,200...63,918,839
JBrowse link
G GLG1 golgi glycoprotein 1 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of GLG1 mRNA CTD PMID:24690739 NCBI chr16:74,447,440...74,607,114
Ensembl chr16:74,447,427...74,607,144
JBrowse link
G GLRX2 glutaredoxin 2 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of GLRX2 mRNA CTD PMID:24690739 NCBI chr 1:193,096,465...193,106,114
Ensembl chr 1:193,090,866...193,106,114
JBrowse link
G GOSR2 golgi SNAP receptor complex member 2 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of GOSR2 mRNA CTD PMID:24690739 NCBI chr17:46,923,160...46,975,890
Ensembl chr17:46,923,075...46,975,524
JBrowse link
G GPSM1 G protein signaling modulator 1 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of GPSM1 mRNA CTD PMID:24690739 NCBI chr 9:136,327,539...136,359,601
Ensembl chr 9:136,327,476...136,359,605
JBrowse link
G GPT2 glutamic--pyruvic transaminase 2 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of GPT2 mRNA CTD PMID:24690739 NCBI chr16:46,884,362...46,931,289
Ensembl chr16:46,884,362...46,931,289
JBrowse link
G GPX3 glutathione peroxidase 3 increases expression EXP Disulfiram results in increased expression of GPX3 mRNA CTD PMID:20566472 NCBI chr 5:151,020,591...151,028,988
Ensembl chr 5:151,020,591...151,028,988
JBrowse link
G GRAMD1A GRAM domain containing 1A multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of GRAMD1A mRNA CTD PMID:24690739 NCBI chr19:34,994,727...35,026,469
Ensembl chr19:34,994,784...35,026,471
JBrowse link
G GRAMD2B GRAM domain containing 2B multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of GRAMD2B mRNA CTD PMID:24690739 NCBI chr 5:126,360,120...126,494,364
Ensembl chr 5:126,360,132...126,496,494
JBrowse link
G GRWD1 glutamate rich WD repeat containing 1 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of GRWD1 mRNA CTD PMID:24690739 NCBI chr19:48,445,983...48,457,022
Ensembl chr19:48,445,841...48,457,022
JBrowse link
G GSDMD gasdermin D decreases cleavage
multiple interactions
EXP Disulfiram results in decreased cleavage of GSDMD protein
Disulfiram binds to and results in decreased activity of GSDMD protein; Disulfiram inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of GSDMD protein]
CTD PMID:32367036 PMID:33851234 NCBI chr 8:143,553,387...143,563,062
Ensembl chr 8:143,553,207...143,563,062
JBrowse link
G GSDME gasdermin E multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of GSDME mRNA CTD PMID:24690739 NCBI chr 7:24,698,355...24,795,539
Ensembl chr 7:24,698,355...24,757,940
JBrowse link
G GSR glutathione-disulfide reductase increases expression EXP Disulfiram results in increased expression of GSR mRNA CTD PMID:20566472 NCBI chr 8:30,678,066...30,727,846
Ensembl chr 8:30,678,066...30,727,846
JBrowse link
G GTF2B general transcription factor IIB multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of GTF2B mRNA CTD PMID:24690739 NCBI chr 1:88,852,633...88,891,567
Ensembl chr 1:88,852,633...88,891,944
JBrowse link
G H2AC19 H2A clustered histone 19 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of H2AC19 mRNA CTD PMID:24690739 NCBI chr 1:149,851,061...149,851,594
Ensembl chr 1:149,851,061...149,851,594
JBrowse link
G H2AC20 H2A clustered histone 20 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of H2AC20 mRNA CTD PMID:24690739 NCBI chr 1:149,886,918...149,887,411
Ensembl chr 1:149,886,918...149,887,411
JBrowse link
G H2AX H2A.X variant histone multiple interactions
increases expression
EXP Disulfiram inhibits the reaction [captax results in increased expression of H2AX protein]; Disulfiram inhibits the reaction [propylene dichloride results in increased phosphorylation of H2AX protein]; Disulfiram inhibits the reaction [Trichloroethylene results in increased phosphorylation of H2AX protein]
Disulfiram results in increased expression of H2AX protein
CTD PMID:28300663 PMID:29722447 PMID:34830855 PMID:35279910 NCBI chr11:119,093,874...119,095,465
Ensembl chr11:119,093,874...119,095,465
JBrowse link
G H2BC12 H2B clustered histone 12 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of H2BC12 mRNA CTD PMID:24690739 NCBI chr 6:27,138,293...27,146,858
Ensembl chr 6:27,137,298...27,146,855
JBrowse link
G H2BC8 H2B clustered histone 8 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of H2BC8 mRNA CTD PMID:24690739 NCBI chr 6:26,216,200...26,216,688
Ensembl chr 6:26,216,200...26,216,688
JBrowse link
G H3-4 H3.4 histone, cluster member multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of H3-4 mRNA CTD PMID:24690739 NCBI chr 1:228,424,845...228,425,360
Ensembl chr 1:228,424,845...228,425,360
JBrowse link
G H3C12 H3 clustered histone 12 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of H3C12 mRNA CTD PMID:24690739 NCBI chr 6:27,890,315...27,890,826
Ensembl chr 6:27,890,315...27,893,106
JBrowse link
G H6PD hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of H6PD mRNA CTD PMID:24690739 NCBI chr 1:9,234,774...9,271,337
Ensembl chr 1:9,234,774...9,271,337
JBrowse link
G HBA1 hemoglobin subunit alpha 1 multiple interactions
increases expression
EXP [Disulfiram binds to Copper] which results in decreased expression of HBA1 mRNA
Disulfiram results in increased expression of HBA1 protein
CTD PMID:24690739 PMID:34182011 NCBI chr16:176,680...177,522
Ensembl chr16:176,680...177,522
JBrowse link
G HBEGF heparin binding EGF like growth factor multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of HBEGF mRNA CTD PMID:24690739 NCBI chr 5:140,332,843...140,346,603
Ensembl chr 5:140,332,843...140,346,603
JBrowse link
G HBG2 hemoglobin subunit gamma 2 increases expression
multiple interactions
EXP Disulfiram results in increased expression of HBG2 protein
Disulfiram promotes the reaction [Primaquine results in increased expression of HBG2 protein]
CTD PMID:19616568 NCBI chr11:5,253,188...5,254,781
Ensembl chr11:5,253,188...5,505,605
JBrowse link
G HES1 hes family bHLH transcription factor 1 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of HES1 mRNA CTD PMID:24690739 NCBI chr 3:194,136,148...194,138,732
Ensembl chr 3:194,136,148...194,138,732
JBrowse link
G HES6 hes family bHLH transcription factor 6 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of HES6 mRNA CTD PMID:24690739 NCBI chr 2:238,238,267...238,240,038
Ensembl chr 2:238,238,267...238,240,662
JBrowse link
G HLA-B major histocompatibility complex, class I, B multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of HLA-B mRNA CTD PMID:24690739 NCBI chr 6:31,353,875...31,357,179
Ensembl chr 6:31,353,872...31,367,067
JBrowse link
G HLA-F major histocompatibility complex, class I, F multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of HLA-F mRNA CTD PMID:24690739 NCBI chr 6:29,723,434...29,738,532
Ensembl chr 6:29,722,775...29,738,528
JBrowse link
G HMOX1 heme oxygenase 1 increases expression
multiple interactions
EXP Disulfiram results in increased expression of HMOX1 mRNA
[Disulfiram binds to Copper] which results in decreased expression of HMOX1 mRNA; [Disulfiram co-treated with Zinc Sulfate] results in increased expression of HMOX1 mRNA; MTF1 protein affects the reaction [Disulfiram results in increased expression of HMOX1 mRNA]
CTD PMID:20566472 PMID:24690739 PMID:32661532 PMID:32712770 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214
JBrowse link
G HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of HNRNPA2B1 mRNA CTD PMID:24690739 NCBI chr 7:26,189,927...26,200,746
Ensembl chr 7:26,171,151...26,201,529
JBrowse link
G HOXA1 homeobox A1 multiple interactions ISO Disulfiram inhibits the reaction [Vitamin A results in increased expression of HOXA1 mRNA] CTD PMID:23696197 NCBI chr 7:27,092,993...27,096,000
Ensembl chr 7:27,092,993...27,096,000
JBrowse link
G HOXD1 homeobox D1 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of HOXD1 mRNA CTD PMID:24690739 NCBI chr 2:176,188,668...176,190,907
Ensembl chr 2:176,188,668...176,190,907
JBrowse link
G HRK harakiri, BCL2 interacting protein multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of HRK mRNA CTD PMID:24690739 NCBI chr12:116,856,144...116,881,441
Ensembl chr12:116,856,144...116,881,441
JBrowse link
G HS3ST2 heparan sulfate-glucosamine 3-sulfotransferase 2 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of HS3ST2 mRNA CTD PMID:24690739 NCBI chr16:22,814,162...22,916,338
Ensembl chr16:22,814,162...22,916,338
JBrowse link
G HSD11B1 hydroxysteroid 11-beta dehydrogenase 1 multiple interactions EXP [Disulfiram co-treated with NAD] binds to HSD11B1 protein CTD PMID:25526675 NCBI chr 1:209,686,179...209,734,929
Ensembl chr 1:209,686,178...209,734,949
JBrowse link
G HSD11B2 hydroxysteroid 11-beta dehydrogenase 2 decreases activity EXP Disulfiram results in decreased activity of HSD11B2 protein CTD PMID:22796344 NCBI chr16:67,429,801...67,437,553
Ensembl chr16:67,430,652...67,437,553
JBrowse link
G HSP90AA1 heat shock protein 90 alpha family class A member 1 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of HSP90AA1 mRNA CTD PMID:24690739 NCBI chr14:102,080,742...102,139,749
Ensembl chr14:102,080,742...102,139,699
JBrowse link
G HSP90AB1 heat shock protein 90 alpha family class B member 1 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of HSP90AB1 mRNA CTD PMID:24690739 NCBI chr 6:44,246,194...44,253,883
Ensembl chr 6:44,246,166...44,253,888
JBrowse link
G HSPA1A heat shock protein family A (Hsp70) member 1A multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of HSPA1A mRNA CTD PMID:24690739 NCBI chr 6:31,815,543...31,817,942
Ensembl chr 6:31,815,543...31,817,946
JBrowse link
G HSPA1B heat shock protein family A (Hsp70) member 1B increases expression
multiple interactions
EXP Disulfiram results in increased expression of HSPA1B mRNA
[Disulfiram binds to Copper] which results in decreased expression of HSPA1B mRNA
CTD PMID:20566472 PMID:24690739 NCBI chr 6:31,827,738...31,830,254
Ensembl chr 6:31,827,738...31,830,254
JBrowse link
G HSPA1L heat shock protein family A (Hsp70) member 1 like multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of HSPA1L mRNA CTD PMID:24690739 NCBI chr 6:31,809,619...31,815,283
Ensembl chr 6:31,809,619...31,815,283
JBrowse link
G HSPA4 heat shock protein family A (Hsp70) member 4 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of HSPA4 mRNA CTD PMID:24690739 NCBI chr 5:133,052,013...133,106,449
Ensembl chr 5:133,052,013...133,106,449
JBrowse link
G HSPA6 heat shock protein family A (Hsp70) member 6 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of HSPA6 mRNA CTD PMID:24690739 NCBI chr 1:161,524,540...161,526,894
Ensembl chr 1:161,524,540...161,526,894
JBrowse link
G HSPA8 heat shock protein family A (Hsp70) member 8 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of HSPA8 mRNA CTD PMID:24690739 NCBI chr11:123,057,489...123,062,462
Ensembl chr11:123,057,489...123,063,230
JBrowse link
G HSPB1 heat shock protein family B (small) member 1 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of HSPB1 mRNA CTD PMID:24690739 NCBI chr 7:76,302,673...76,304,292
Ensembl chr 7:76,302,673...76,305,813
JBrowse link
G HSPB8 heat shock protein family B (small) member 8 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of HSPB8 mRNA CTD PMID:24690739 NCBI chr12:119,178,931...119,194,746
Ensembl chr12:119,171,555...119,224,855
JBrowse link
G HSPH1 heat shock protein family H (Hsp110) member 1 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of HSPH1 mRNA CTD PMID:24690739 NCBI chr13:31,134,973...31,162,388
Ensembl chr13:31,134,973...31,162,388
JBrowse link
G HTR2B 5-hydroxytryptamine receptor 2B multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of HTR2B mRNA CTD PMID:24690739 NCBI chr 2:231,108,230...231,125,042
Ensembl chr 2:231,108,230...231,125,042
JBrowse link
G ID2 inhibitor of DNA binding 2 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of ID2 mRNA CTD PMID:24690739 NCBI chr 2:8,682,056...8,684,461
Ensembl chr 2:8,678,845...8,684,461
JBrowse link
G IER5 immediate early response 5 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of IER5 mRNA CTD PMID:24690739 NCBI chr 1:181,088,700...181,092,900
Ensembl chr 1:181,088,700...181,092,900
JBrowse link
G IFIT1 interferon induced protein with tetratricopeptide repeats 1 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of IFIT1 mRNA CTD PMID:24690739 NCBI chr10:89,392,623...89,406,487
Ensembl chr10:89,392,546...89,406,487
JBrowse link
G IFIT2 interferon induced protein with tetratricopeptide repeats 2 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of IFIT2 mRNA CTD PMID:24690739 NCBI chr10:89,302,046...89,309,271
Ensembl chr10:89,283,694...89,309,271
JBrowse link
G IFIT3 interferon induced protein with tetratricopeptide repeats 3 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of IFIT3 mRNA CTD PMID:24690739 NCBI chr10:89,327,997...89,340,968
Ensembl chr10:89,327,307...89,377,473
JBrowse link
G IFNGR2 interferon gamma receptor 2 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of IFNGR2 mRNA CTD PMID:24690739 NCBI chr21:33,402,882...33,437,516
Ensembl chr21:33,403,413...33,479,348
JBrowse link
G IGF2-AS IGF2 antisense RNA multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of IGF2-AS mRNA CTD PMID:24690739 NCBI chr11:2,140,512...2,148,666
Ensembl chr11:2,140,501...2,148,666
JBrowse link
G IGF2R insulin like growth factor 2 receptor multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of IGF2R mRNA CTD PMID:24690739 NCBI chr 6:159,969,082...160,111,504
Ensembl chr 6:159,969,082...160,113,507
JBrowse link
G IGFBP7 insulin like growth factor binding protein 7 multiple interactions
increases expression
EXP [Disulfiram binds to Copper] which results in increased expression of IGFBP7 mRNA; [Disulfiram binds to Copper] which results in increased expression of IGFBP7 protein
[Disulfiram cotreated with copper(+2)] increases expression of IGFBP7 mRNA in malignant pleural mesothelioma cells
CTD
RGD
PMID:24690739 PMID:24690739 RGD:401960877 NCBI chr 4:57,030,773...57,110,385
Ensembl chr 4:57,030,773...57,110,385
JBrowse link
G IL18 interleukin 18 multiple interactions EXP [Disulfiram co-treated with Adenosine Triphosphate] inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of IL18 protein]; Disulfiram inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of IL18 protein] CTD PMID:33579316 PMID:33851234 NCBI chr11:112,143,260...112,164,094
Ensembl chr11:112,143,251...112,164,096
JBrowse link
G IL1A interleukin 1 alpha multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of IL1A mRNA CTD PMID:24690739 NCBI chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493
JBrowse link
G IL1B interleukin 1 beta multiple interactions EXP
ISO
[Disulfiram binds to Copper] which results in increased expression of IL1B mRNA; [Disulfiram co-treated with Adenosine Triphosphate] inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of IL1B protein]; [Disulfiram co-treated with Zinc Sulfate] inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]; Disulfiram inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of IL1B protein]; Disulfiram inhibits the reaction [Nigericin results in increased secretion of IL1B protein]
Disulfiram inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]
CTD PMID:24690739 PMID:32367036 PMID:32712770 PMID:33579316 PMID:33851234 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816
JBrowse link
G IL6 interleukin 6 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of IL6 mRNA; [Disulfiram co-treated with Zinc Sulfate] inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]; Disulfiram inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of IL6 protein] CTD PMID:24690739 PMID:32712770 PMID:33851234 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002
JBrowse link
G INSIG1 insulin induced gene 1 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of INSIG1 mRNA CTD PMID:24690739 NCBI chr 7:155,297,878...155,310,235
Ensembl chr 7:155,297,776...155,310,235
JBrowse link
G IRF8 interferon regulatory factor 8 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of IRF8 mRNA CTD PMID:24690739 NCBI chr16:85,899,162...85,922,609
Ensembl chr16:85,899,116...85,922,606
JBrowse link
G ISY1 ISY1 splicing factor homolog multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of ISY1 mRNA CTD PMID:24690739 NCBI chr 3:129,127,415...129,161,063
Ensembl chr 3:129,127,415...129,161,063
JBrowse link
G ITGA11 integrin subunit alpha 11 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of ITGA11 mRNA CTD PMID:24690739 NCBI chr15:68,296,532...68,432,163
Ensembl chr15:68,296,532...68,432,163
JBrowse link
G ITGA3 integrin subunit alpha 3 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of ITGA3 mRNA CTD PMID:24690739 NCBI chr17:50,056,110...50,090,481
Ensembl chr17:50,055,968...50,090,481
JBrowse link
G ITGAM integrin subunit alpha M increases expression EXP Disulfiram results in increased expression of ITGAM protein CTD PMID:32712770 NCBI chr16:31,259,975...31,332,877
Ensembl chr16:31,259,967...31,332,892
JBrowse link
G ITGAV integrin subunit alpha V multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of ITGAV mRNA CTD PMID:24690739 NCBI chr 2:186,590,056...186,680,901
Ensembl chr 2:186,590,010...186,680,901
JBrowse link
G ITGB1 integrin subunit beta 1 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of ITGB1 mRNA CTD PMID:24690739 NCBI chr10:32,900,318...32,958,230
Ensembl chr10:32,887,273...33,005,792
JBrowse link
G ITGB5 integrin subunit beta 5 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of ITGB5 mRNA CTD PMID:24690739 NCBI chr 3:124,761,948...124,901,418
Ensembl chr 3:124,761,948...124,901,418
JBrowse link
G JAG2 jagged canonical Notch ligand 2 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of JAG2 mRNA CTD PMID:24690739 NCBI chr14:105,140,995...105,168,776
Ensembl chr14:105,140,982...105,168,824
JBrowse link
G JSRP1 junctional sarcoplasmic reticulum protein 1 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of JSRP1 mRNA CTD PMID:24690739 NCBI chr19:2,252,252...2,256,417
Ensembl chr19:2,252,252...2,269,759
JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP [Copper co-treated with Disulfiram co-treated with Gemcitabine] results in increased expression of and results in increased phosphorylation of JUN protein; [Copper co-treated with Disulfiram] results in increased expression of and results in increased phosphorylation of JUN protein; [Disulfiram co-treated with cupric chloride co-treated with Doxorubicin] results in increased expression of and results in increased phosphorylation of JUN protein; Acetylcysteine inhibits the reaction [[Copper co-treated with Disulfiram] results in increased phosphorylation of JUN protein]; pyrazolanthrone inhibits the reaction [[Disulfiram co-treated with Copper co-treated with Doxorubicin] results in increased phosphorylation of and results in increased expression of JUN protein] CTD PMID:21911303 PMID:23033007 NCBI chr 1:58,780,791...58,784,047
Ensembl chr 1:58,776,845...58,784,048
JBrowse link
G KCNG1 potassium voltage-gated channel modifier subfamily G member 1 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of KCNG1 mRNA CTD PMID:24690739 NCBI chr20:51,003,656...51,023,107
Ensembl chr20:51,003,656...51,023,107
JBrowse link
G KHDRBS3 KH RNA binding domain containing, signal transduction associated 3 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of KHDRBS3 mRNA CTD PMID:24690739 NCBI chr 8:135,457,456...135,656,516
Ensembl chr 8:135,457,456...135,656,722
JBrowse link
G KLF10 KLF transcription factor 10 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of KLF10 mRNA CTD PMID:24690739 NCBI chr 8:102,648,784...102,655,725
Ensembl chr 8:102,648,784...102,655,725
JBrowse link
G KLHL22 kelch like family member 22 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of KLHL22 mRNA CTD PMID:24690739 NCBI chr22:20,441,519...20,495,795
Ensembl chr22:20,441,519...20,495,844
JBrowse link
G KLHL5 kelch like family member 5 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of KLHL5 mRNA CTD PMID:24690739 NCBI chr 4:39,044,827...39,143,101
Ensembl chr 4:39,045,039...39,126,857
JBrowse link
G KRT1 keratin 1 increases expression EXP Disulfiram results in increased expression of KRT1 mRNA; Disulfiram results in increased expression of KRT1 protein CTD PMID:34182011 NCBI chr12:52,674,736...52,680,407
Ensembl chr12:52,674,736...52,680,407
JBrowse link
G KRT75 keratin 75 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of KRT75 mRNA CTD PMID:24690739 NCBI chr12:52,424,070...52,434,371
Ensembl chr12:52,424,070...52,434,371
JBrowse link
G LAMC1 laminin subunit gamma 1 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of LAMC1 mRNA CTD PMID:24690739 NCBI chr 1:183,023,420...183,145,592
Ensembl chr 1:183,023,420...183,145,592
JBrowse link
G LAMTOR3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of LAMTOR3 mRNA CTD PMID:24690739 NCBI chr 4:99,878,336...99,894,546
Ensembl chr 4:99,878,336...99,894,428
JBrowse link
G LEMD2 LEM domain nuclear envelope protein 2 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of LEMD2 mRNA CTD PMID:24690739 NCBI chr 6:33,771,213...33,789,130
Ensembl chr 6:33,771,202...33,789,130
JBrowse link
G LHB luteinizing hormone subunit beta multiple interactions ISO Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of BMP7 mRNA]; Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of CCND2 mRNA]; Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of CYP17A1 mRNA]; Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of CYP19A1 mRNA]; Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of FSHR mRNA]; Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of LHCGR mRNA]; Tretinoin inhibits the reaction [Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of LHCGR mRNA]] CTD PMID:22285649 NCBI chr19:49,015,980...49,019,498
Ensembl chr19:49,015,980...49,017,091
JBrowse link
G LHCGR luteinizing hormone/choriogonadotropin receptor multiple interactions ISO Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of LHCGR mRNA]; Tretinoin inhibits the reaction [Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of LHCGR mRNA]] CTD PMID:22285649 NCBI chr 2:48,686,774...48,755,724
Ensembl chr 2:48,686,774...48,755,730
JBrowse link
G LIMCH1 LIM and calponin homology domains 1 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of LIMCH1 mRNA CTD PMID:24690739 NCBI chr 4:41,359,607...41,700,044
Ensembl chr 4:41,359,607...41,700,044
JBrowse link
G LINC01554 long intergenic non-protein coding RNA 1554 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of LINC01554 mRNA CTD PMID:24690739 NCBI chr 5:95,852,232...95,860,133
Ensembl chr 5:95,838,244...95,860,141
JBrowse link
G LIPT1 lipoyltransferase 1 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of LIPT1 mRNA CTD PMID:24690739 NCBI chr 2:99,154,967...99,163,137
Ensembl chr 2:99,154,955...99,163,157
JBrowse link
G LMCD1 LIM and cysteine rich domains 1 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of LMCD1 mRNA CTD PMID:24690739 NCBI chr 3:8,501,823...8,574,668
Ensembl chr 3:8,501,807...8,574,668
JBrowse link
G LMTK2 lemur tyrosine kinase 2 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of LMTK2 mRNA CTD PMID:24690739 NCBI chr 7:98,106,862...98,209,638
Ensembl chr 7:98,106,862...98,209,638
JBrowse link
G LORICRIN loricrin cornified envelope precursor protein multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of LORICRIN mRNA CTD PMID:24690739 NCBI chr 1:153,259,687...153,262,124
Ensembl chr 1:153,259,687...153,262,124
JBrowse link
G LRATD2 LRAT domain containing 2 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of LRATD2 mRNA CTD PMID:24690739 NCBI chr 8:126,552,443...126,558,478
Ensembl chr 8:126,552,443...126,558,478
JBrowse link
G LRP8 LDL receptor related protein 8 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of LRP8 mRNA CTD PMID:24690739 NCBI chr 1:53,242,364...53,328,070
Ensembl chr 1:53,242,364...53,328,469
JBrowse link
G LSMEM1 leucine rich single-pass membrane protein 1 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of LSMEM1 mRNA CTD PMID:24690739 NCBI chr 7:112,480,304...112,491,062
Ensembl chr 7:112,480,853...112,491,062
JBrowse link
G LTB4R leukotriene B4 receptor multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of LTB4R mRNA CTD PMID:24690739 NCBI chr14:24,311,502...24,318,036
Ensembl chr14:24,311,450...24,318,036
JBrowse link
G LUC7L3 LUC7 like 3 pre-mRNA splicing factor multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of CROP mRNA CTD PMID:24690739 NCBI chr17:50,719,603...50,756,219
Ensembl chr17:50,719,565...50,756,219
JBrowse link
G MACF1 microtubule actin crosslinking factor 1 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of MACF1 mRNA CTD PMID:24690739 NCBI chr 1:39,084,167...39,487,138
Ensembl chr 1:39,081,316...39,487,177
JBrowse link
G MAD2L1BP MAD2L1 binding protein multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of MAD2L1BP mRNA CTD PMID:24690739 NCBI chr 6:43,629,540...43,640,941
Ensembl chr 6:43,629,540...43,640,941
JBrowse link
G MAFB MAF bZIP transcription factor B multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of MAFB mRNA CTD PMID:24690739 NCBI chr20:40,685,848...40,689,236
Ensembl chr20:40,685,848...40,689,236
JBrowse link
G MAFF MAF bZIP transcription factor F increases expression EXP Disulfiram results in increased expression of MAFF mRNA CTD PMID:20566472 NCBI chr22:38,201,994...38,216,511
Ensembl chr22:38,200,767...38,216,507
JBrowse link
G MAFG MAF bZIP transcription factor G increases expression EXP Disulfiram results in increased expression of MAFG mRNA CTD PMID:20566472 NCBI chr17:81,918,270...81,931,244
Ensembl chr17:81,918,270...81,927,735
JBrowse link
G MAFK MAF bZIP transcription factor K increases expression EXP Disulfiram results in increased expression of MAFK mRNA CTD PMID:20566472 NCBI chr 7:1,530,702...1,543,043
Ensembl chr 7:1,530,702...1,543,043
JBrowse link
G MAGOH mago homolog, exon junction complex subunit multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of MAGOH mRNA CTD PMID:24690739 NCBI chr 1:53,226,900...53,238,518
Ensembl chr 1:53,226,900...53,238,518
JBrowse link
G MAN1B1 mannosidase alpha class 1B member 1 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of MAN1B1 mRNA CTD PMID:24690739 NCBI chr 9:137,086,985...137,109,183
Ensembl chr 9:137,086,857...137,109,189
JBrowse link
G MAOA monoamine oxidase A multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of MAOA mRNA CTD PMID:24690739 NCBI chr  X:43,655,006...43,746,817
Ensembl chr  X:43,654,907...43,746,817
JBrowse link
G MAP1LC3B microtubule associated protein 1 light chain 3 beta multiple interactions
increases expression
EXP [Disulfiram binds to Copper] which results in decreased expression of MAP1LC3B mRNA
Disulfiram results in increased expression of MAP1LC3B mRNA
CTD PMID:24690739 PMID:34182011 NCBI chr16:87,392,336...87,404,774
Ensembl chr16:87,383,953...87,404,779
JBrowse link
G MAP2K3 mitogen-activated protein kinase kinase 3 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of MAP2K3 mRNA CTD PMID:24690739 NCBI chr17:21,284,711...21,315,240
Ensembl chr17:21,284,672...21,315,232
JBrowse link
G MAP3K13 mitogen-activated protein kinase kinase kinase 13 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of MAP3K13 mRNA CTD PMID:24690739 NCBI chr 3:185,282,961...185,489,094
Ensembl chr 3:185,282,941...185,489,094
JBrowse link
G MAP3K20 mitogen-activated protein kinase kinase kinase 20 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of MAP3K20 mRNA CTD PMID:24690739 NCBI chr 2:173,075,517...173,268,015
Ensembl chr 2:173,075,435...173,268,015
JBrowse link
G MAPK1 mitogen-activated protein kinase 1 multiple interactions EXP [Copper co-treated with Disulfiram co-treated with Gemcitabine] results in increased phosphorylation of MAPK1 protein; [Copper co-treated with Disulfiram] results in increased phosphorylation of MAPK1 protein CTD PMID:23033007 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680
JBrowse link
G MAPK3 mitogen-activated protein kinase 3 multiple interactions EXP [Copper co-treated with Disulfiram co-treated with Gemcitabine] results in increased phosphorylation of MAPK3 protein; [Copper co-treated with Disulfiram] results in increased phosphorylation of MAPK3 protein CTD PMID:23033007 NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506
JBrowse link
G MAPK8 mitogen-activated protein kinase 8 multiple interactions ISO
EXP
[Disulfiram binds to cupric chloride] which results in increased activity of MAPK8 protein; bathocuproine sulfonate inhibits the reaction [[Disulfiram binds to cupric chloride] which results in increased activity of MAPK8 protein]
[Disulfiram binds to Copper] which results in increased phosphorylation of MAPK8 protein
CTD PMID:11239917 PMID:24690739 NCBI chr10:48,306,677...48,439,360
Ensembl chr10:48,306,639...48,439,360
JBrowse link
G MAPK9 mitogen-activated protein kinase 9 multiple interactions EXP
ISO
[Disulfiram binds to Copper] which results in increased phosphorylation of MAPK9 protein CTD PMID:24690739 NCBI chr 5:180,233,143...180,292,083
Ensembl chr 5:180,233,143...180,292,099
JBrowse link
G MAPRE2 microtubule associated protein RP/EB family member 2 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of MAPRE2 mRNA CTD PMID:24690739 NCBI chr18:34,977,027...35,143,470
Ensembl chr18:34,976,928...35,143,470
JBrowse link
G MCM2 minichromosome maintenance complex component 2 multiple interactions
decreases expression
EXP cupric chloride promotes the reaction [Disulfiram results in decreased expression of MCM2 mRNA] CTD PMID:19789329 NCBI chr 3:127,598,411...127,622,436
Ensembl chr 3:127,598,223...127,622,436
JBrowse link
G MCM5 minichromosome maintenance complex component 5 multiple interactions
decreases expression
EXP cupric chloride promotes the reaction [Disulfiram results in decreased expression of MCM5 mRNA] CTD PMID:19789329 NCBI chr22:35,400,140...35,455,031
Ensembl chr22:35,400,134...35,425,431
JBrowse link
G ME1 malic enzyme 1 increases expression EXP Disulfiram results in increased expression of ME1 mRNA CTD PMID:20566472 NCBI chr 6:83,210,402...83,431,051
Ensembl chr 6:83,210,402...83,431,051
JBrowse link
G MFSD3 major facilitator superfamily domain containing 3 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of MFSD3 mRNA CTD PMID:24690739 NCBI chr 8:144,509,070...144,511,213
Ensembl chr 8:144,509,070...144,511,213
JBrowse link
G MGMT O-6-methylguanine-DNA methyltransferase multiple interactions
decreases activity
increases degradation
EXP
ISO
[Disulfiram binds to Copper] which results in decreased expression of and results in decreased activity of MGMT protein; [Disulfiram co-treated with cupric chloride] affects the expression of and affects the activity of MGMT protein; bortezomib inhibits the reaction [Disulfiram results in increased degradation of MGMT protein]; Disulfiram inhibits the reaction [O(6)-benzylguanine binds to MGMT protein]; Disulfiram results in decreased expression of and results in decreased activity of MGMT protein
Disulfiram results in decreased activity of MGMT protein
CTD PMID:24193513 NCBI chr10:129,467,241...129,770,983
Ensembl chr10:129,467,190...129,770,983
JBrowse link
G MGST1 microsomal glutathione S-transferase 1 increases expression EXP Disulfiram results in increased expression of MGST1 mRNA CTD PMID:20566472 NCBI chr12:16,347,115...16,593,331
Ensembl chr12:16,347,142...16,609,259
JBrowse link
G MIDN midnolin multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of MIDN mRNA CTD PMID:24690739 NCBI chr19:1,248,583...1,259,143
Ensembl chr19:1,248,553...1,259,143
JBrowse link
G MIF macrophage migration inhibitory factor increases expression EXP Disulfiram results in increased expression of MIF protein CTD PMID:34182011 NCBI chr22:23,894,383...23,895,223
Ensembl chr22:23,894,383...23,895,227
JBrowse link
G MIX23 mitochondrial matrix import factor 23 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of MIX23 mRNA CTD PMID:24690739 NCBI chr 3:122,359,591...122,383,231
Ensembl chr 3:122,359,591...122,383,231
JBrowse link
G MMP10 matrix metallopeptidase 10 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of MMP10 mRNA CTD PMID:24690739 NCBI chr11:102,770,502...102,780,628
Ensembl chr11:102,770,502...102,780,628
JBrowse link
G MMP2 matrix metallopeptidase 2 decreases expression EXP Disulfiram results in decreased expression of MMP2 CTD PMID:18047805 NCBI chr16:55,478,830...55,506,691
Ensembl chr16:55,389,700...55,506,691
JBrowse link
G MMP3 matrix metallopeptidase 3 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of MMP3 mRNA CTD PMID:24690739 NCBI chr11:102,835,801...102,843,609
Ensembl chr11:102,835,801...102,843,609
JBrowse link
G MMP9 matrix metallopeptidase 9 decreases expression EXP Disulfiram results in decreased expression of MMP9 CTD PMID:18047805 NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561
JBrowse link
G MPPE1 metallophosphoesterase 1 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of MPPE1 mRNA CTD PMID:24690739 NCBI chr18:11,882,622...11,908,317
Ensembl chr18:11,882,622...11,908,366
JBrowse link
G MRPL10 mitochondrial ribosomal protein L10 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of MRPL10 mRNA CTD PMID:24690739 NCBI chr17:47,823,272...47,831,541
Ensembl chr17:47,823,272...47,831,541
JBrowse link
G MRPL18 mitochondrial ribosomal protein L18 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of MRPL18 mRNA CTD PMID:24690739 NCBI chr 6:159,789,812...159,798,429
Ensembl chr 6:159,789,812...159,798,436
JBrowse link
G MRPL45 mitochondrial ribosomal protein L45 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of MRPL45 mRNA CTD PMID:24690739 NCBI chr17:38,297,168...38,323,211
Ensembl chr17:38,297,023...38,323,217
JBrowse link
G MST1 macrophage stimulating 1 increases expression EXP Disulfiram results in increased expression of MST1 mRNA CTD PMID:34182011 NCBI chr 3:49,683,947...49,689,474
Ensembl chr 3:49,683,947...49,689,501
JBrowse link
G MT-CO1 mitochondrially encoded cytochrome c oxidase I affects activity
affects expression
ISO Disulfiram affects the activity of COX1 protein
Disulfiram affects the expression of COX1 mRNA
CTD PMID:17936468 NCBI chr MT:5,904...7,445
Ensembl chr MT:5,904...7,445
JBrowse link
G MT1A metallothionein 1A multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of MT1A mRNA CTD PMID:24690739 NCBI chr16:56,638,666...56,640,087
Ensembl chr16:56,638,666...56,640,087
JBrowse link
G MT1B metallothionein 1B increases expression
multiple interactions
EXP Disulfiram results in increased expression of MT1B mRNA
[Disulfiram binds to Copper] which results in decreased expression of MT1B mRNA; cupric chloride promotes the reaction [Disulfiram results in increased expression of MT1B mRNA]
CTD PMID:19789329 PMID:24690739 NCBI chr16:56,651,886...56,653,204
Ensembl chr16:56,651,886...56,653,204
JBrowse link
G MT1F metallothionein 1F multiple interactions
increases expression
EXP [Disulfiram binds to Copper] which results in decreased expression of MT1F mRNA; cupric chloride promotes the reaction [Disulfiram results in increased expression of MT1F mRNA] CTD PMID:19789329 PMID:24690739 NCBI chr16:56,657,959...56,659,303
Ensembl chr16:56,657,731...56,660,698
JBrowse link
G MT1G metallothionein 1G multiple interactions
increases expression
EXP [Disulfiram binds to Copper] which results in decreased expression of MT1G mRNA; cupric chloride promotes the reaction [Disulfiram results in increased expression of MT1G mRNA] CTD PMID:19789329 PMID:24690739 NCBI chr16:56,666,730...56,668,065
Ensembl chr16:56,666,730...56,668,065
JBrowse link
G MT1L metallothionein 1L (pseudogene) multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of MT1L mRNA CTD PMID:24690739 NCBI chr16:56,617,461...56,618,818
Ensembl chr16:56,617,563...56,618,680
JBrowse link
G MT1M metallothionein 1M increases expression
multiple interactions
EXP Disulfiram results in increased expression of MT1M mRNA
MTF1 protein affects the reaction [Disulfiram results in increased expression of MT1M mRNA]
CTD PMID:32661532 NCBI chr16:56,632,659...56,633,981
Ensembl chr16:56,632,659...56,633,981
JBrowse link
G MT1X metallothionein 1X increases expression
multiple interactions
EXP Disulfiram results in increased expression of MT1X mRNA
[Disulfiram binds to Copper] which results in decreased expression of MT1X mRNA; cupric chloride promotes the reaction [Disulfiram results in increased expression of MT1X mRNA]
CTD PMID:19789329 PMID:20566472 PMID:24690739 NCBI chr16:56,682,470...56,684,196
Ensembl chr16:56,682,470...56,684,196
JBrowse link
G MT2A metallothionein 2A multiple interactions
increases expression
EXP cupric chloride promotes the reaction [Disulfiram results in increased expression of MT2A mRNA]; MTF1 protein affects the reaction [Disulfiram results in increased expression of MT2A mRNA] CTD PMID:19789329 PMID:32661532 NCBI chr16:56,608,584...56,609,497
Ensembl chr16:56,608,584...56,609,497
JBrowse link
G MT3 metallothionein 3 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of MT3 mRNA CTD PMID:24690739 NCBI chr16:56,589,528...56,591,085
Ensembl chr16:56,589,074...56,591,088
JBrowse link
G MTF1 metal regulatory transcription factor 1 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of MTF1 mRNA; MTF1 protein affects the reaction [Disulfiram results in increased expression of ATF3 mRNA]; MTF1 protein affects the reaction [Disulfiram results in increased expression of HMOX1 mRNA]; MTF1 protein affects the reaction [Disulfiram results in increased expression of MT1M mRNA]; MTF1 protein affects the reaction [Disulfiram results in increased expression of MT2A mRNA] CTD PMID:24690739 PMID:32661532 NCBI chr 1:37,809,574...37,859,592
Ensembl chr 1:37,809,574...37,859,592
JBrowse link
G MX1 MX dynamin like GTPase 1 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of MX1 mRNA CTD PMID:24690739 NCBI chr21:41,420,558...41,459,214
Ensembl chr21:41,420,020...41,470,071
JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor decreases expression EXP Disulfiram results in decreased expression of MYC mRNA CTD PMID:34182011 NCBI chr 8:127,735,434...127,742,951
Ensembl chr 8:127,735,434...127,742,951
JBrowse link
G MYLIP myosin regulatory light chain interacting protein multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of MYLIP mRNA CTD PMID:24690739 NCBI chr 6:16,129,086...16,163,887
Ensembl chr 6:16,129,086...16,151,367
JBrowse link
G MYLK myosin light chain kinase multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of MYLK mRNA CTD PMID:24690739 NCBI chr 3:123,610,049...123,884,332
Ensembl chr 3:123,610,049...123,884,332
JBrowse link
G NAT14 N-acetyltransferase 14 (putative) multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of NAT14 mRNA CTD PMID:24690739 NCBI chr19:55,485,188...55,487,566
Ensembl chr19:55,485,188...55,487,568
JBrowse link
G NBPF3 NBPF member 3 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of NBPF3 mRNA CTD PMID:24690739 NCBI chr 1:21,436,789...21,484,900
Ensembl chr 1:21,440,128...21,485,005
JBrowse link
G NCEH1 neutral cholesterol ester hydrolase 1 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of NCEH1 mRNA CTD PMID:24690739 NCBI chr 3:172,630,249...172,711,067
Ensembl chr 3:172,630,249...172,711,218
JBrowse link
G NCOA7 nuclear receptor coactivator 7 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of NCOA7 mRNA CTD PMID:24690739 NCBI chr 6:125,781,115...125,932,034
Ensembl chr 6:125,781,161...125,932,034
JBrowse link
G NCSTN nicastrin multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of NCSTN mRNA CTD PMID:24690739 NCBI chr 1:160,343,383...160,358,949
Ensembl chr 1:160,343,294...160,358,952
JBrowse link
G NEFH neurofilament heavy chain multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of NEFH mRNA CTD PMID:24690739 NCBI chr22:29,480,218...29,491,390
Ensembl chr22:29,480,218...29,491,390
JBrowse link
G NFE2L3 NFE2 like bZIP transcription factor 3 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of NFE2L3 mRNA CTD PMID:24690739 NCBI chr 7:26,152,198...26,187,137
Ensembl chr 7:26,152,198...26,187,137
JBrowse link
G NFKB1 nuclear factor kappa B subunit 1 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of NFKB1 mRNA CTD PMID:24690739 NCBI chr 4:102,501,359...102,617,302
Ensembl chr 4:102,501,330...102,617,302
JBrowse link
G NFKBIA NFKB inhibitor alpha decreases degradation
multiple interactions
ISO
EXP
Disulfiram results in decreased degradation of NFKBIA protein
[Disulfiram binds to Copper] which results in increased expression of NFKBIA protein
CTD PMID:10418820 PMID:24690739 NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,079...35,404,749
JBrowse link
G NFKBIB NFKB inhibitor beta multiple interactions EXP
ISO
[Disulfiram binds to Copper] which results in increased expression of NFKBIB protein CTD PMID:24690739 NCBI chr19:38,899,666...38,908,889
Ensembl chr19:38,899,700...38,908,893
JBrowse link
G NGDN neuroguidin multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of NGDN mRNA CTD PMID:24690739 NCBI chr14:23,469,703...23,478,826
Ensembl chr14:23,469,679...23,509,862
JBrowse link
G NIBAN1 niban apoptosis regulator 1 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of NIBAN1 mRNA CTD PMID:24690739 NCBI chr 1:184,791,032...184,974,508
Ensembl chr 1:184,790,724...184,974,508
JBrowse link
G NME1-NME2 NME1-NME2 readthrough multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of NME1-NME2 mRNA CTD PMID:24690739 NCBI chr17:51,153,559...51,171,744
Ensembl chr17:51,153,590...51,171,744
JBrowse link
G NOL12 nucleolar protein 12 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of NOL12 mRNA CTD PMID:24690739 NCBI chr22:37,686,343...37,693,474
Ensembl chr22:37,681,673...37,693,476
JBrowse link
G NOS2 nitric oxide synthase 2 affects expression ISO Disulfiram affects the expression of NOS2 mRNA CTD PMID:17936468 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529
JBrowse link
G NOSIP nitric oxide synthase interacting protein multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of NOSIP mRNA CTD PMID:24690739 NCBI chr19:49,555,468...49,580,556
Ensembl chr19:49,555,468...49,590,262
JBrowse link
G NPEPL1 aminopeptidase like 1 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of NPEPL1 mRNA CTD PMID:24690739 NCBI chr20:58,689,131...58,715,844
Ensembl chr20:58,689,131...58,719,238
JBrowse link
G NPPB natriuretic peptide B multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of NPPB mRNA CTD PMID:24690739 NCBI chr 1:11,857,464...11,858,945
Ensembl chr 1:11,857,464...11,858,945
JBrowse link
G NPTX2 neuronal pentraxin 2 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of NPTX2 mRNA CTD PMID:24690739 NCBI chr 7:98,617,285...98,629,869
Ensembl chr 7:98,617,285...98,629,869
JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 increases expression
increases activity
EXP
ISO
Disulfiram results in increased expression of NQO1 mRNA
Disulfiram results in increased activity of NQO1 protein
CTD PMID:16045903 PMID:20566472 NCBI chr16:69,709,401...69,726,560
Ensembl chr16:69,706,996...69,726,668
JBrowse link
G NR1I2 nuclear receptor subfamily 1 group I member 2 multiple interactions ISO
EXP
Disulfiram binds to and affects the activity of NR1I2 protein
Disulfiram binds to and results in increased activity of NR1I2 protein
CTD PMID:33049310 NCBI chr 3:119,782,101...119,818,487
Ensembl chr 3:119,780,484...119,818,487
JBrowse link
G NRARP NOTCH regulated ankyrin repeat protein multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of NRARP mRNA CTD PMID:24690739 NCBI chr 9:137,299,631...137,302,271
Ensembl chr 9:137,299,631...137,302,271
JBrowse link
G NRAS NRAS proto-oncogene, GTPase multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of NRAS mRNA CTD PMID:24690739 NCBI chr 1:114,704,469...114,716,771
Ensembl chr 1:114,704,469...114,716,771
JBrowse link
G NRP1 neuropilin 1 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of NRP1 mRNA CTD PMID:24690739 NCBI chr10:33,177,493...33,334,667
Ensembl chr10:33,177,492...33,336,262
JBrowse link
G NSUN5P2 NSUN5 pseudogene 2 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of NSUN5P2 mRNA CTD PMID:24690739 NCBI chr 7:72,948,293...72,954,763
Ensembl chr 7:72,947,581...72,954,790
Ensembl chr 7:72,947,581...72,954,790
JBrowse link
G NT5E 5'-nucleotidase ecto multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of NT5E mRNA CTD PMID:24690739 NCBI chr 6:85,450,083...85,495,784
Ensembl chr 6:85,449,584...85,495,791
JBrowse link
G NUBP1 NUBP iron-sulfur cluster assembly factor 1, cytosolic multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of NUBP1 mRNA CTD PMID:24690739 NCBI chr16:10,743,842...10,769,351
Ensembl chr16:10,743,786...10,769,351
JBrowse link
G NXF1 nuclear RNA export factor 1 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of NXF1 mRNA CTD PMID:24690739 NCBI chr11:62,792,130...62,805,440
Ensembl chr11:62,792,123...62,806,302
JBrowse link
G NXT2 nuclear transport factor 2 like export factor 2 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of NXT2 mRNA CTD PMID:24690739 NCBI chr  X:109,535,824...109,544,698
Ensembl chr  X:109,535,781...109,544,698
JBrowse link
G OASL 2'-5'-oligoadenylate synthetase like multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of OASL mRNA CTD PMID:24690739 NCBI chr12:121,017,761...121,039,246
Ensembl chr12:121,017,763...121,039,246
JBrowse link
G OSMR oncostatin M receptor multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of OSMR mRNA CTD PMID:24690739 NCBI chr 5:38,846,012...38,945,579
Ensembl chr 5:38,845,858...38,945,596
JBrowse link
G P3H3 prolyl 3-hydroxylase 3 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of P3H3 mRNA CTD PMID:24690739 NCBI chr12:6,828,407...6,839,847
Ensembl chr12:6,828,407...6,839,847
JBrowse link
G P3H4 prolyl 3-hydroxylase family member 4 (inactive) multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of P3H4 mRNA CTD PMID:24690739 NCBI chr17:41,801,953...41,811,949
Ensembl chr17:41,801,947...41,812,604
JBrowse link
G PAM peptidylglycine alpha-amidating monooxygenase increases activity ISO Disulfiram results in increased activity of PAM protein CTD PMID:8246921 PMID:10347250 NCBI chr 5:102,754,783...103,031,105
Ensembl chr 5:102,753,981...103,029,730
JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 multiple interactions
increases cleavage
EXP
ISO
[Copper co-treated with Disulfiram] results in increased cleavage of PARP1 protein; [Disulfiram binds to Copper] which results in increased cleavage of PARP1 protein; [Disulfiram co-treated with cupric chloride] results in increased cleavage of PARP1 protein; Disulfiram promotes the reaction [Carmustine results in increased cleavage of PARP1 protein]
Disulfiram results in increased cleavage of PARP1 protein
CTD PMID:17079463 PMID:19789329 PMID:23033007 PMID:24193513 PMID:24690739 More... NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,210...226,408,154
JBrowse link
G PCK2 phosphoenolpyruvate carboxykinase 2, mitochondrial multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of PCK2 mRNA CTD PMID:24690739 NCBI chr14:24,094,171...24,104,125
Ensembl chr14:24,094,053...24,110,598
JBrowse link
G PCNX4 pecanex 4 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of PCNX4 mRNA CTD PMID:24690739 NCBI chr14:60,091,911...60,148,221
Ensembl chr14:60,091,911...60,169,133
JBrowse link
G PDE5A phosphodiesterase 5A multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of PDE5A mRNA CTD PMID:24690739 NCBI chr 4:119,494,403...119,628,804
Ensembl chr 4:119,494,397...119,628,804
JBrowse link
G PDGFRB platelet derived growth factor receptor beta multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of PDGFRB mRNA CTD PMID:24690739 NCBI chr 5:150,113,839...150,155,845
Ensembl chr 5:150,113,839...150,155,872
JBrowse link
G PDLIM5 PDZ and LIM domain 5 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of PDLIM5 mRNA CTD PMID:24690739 NCBI chr 4:94,451,942...94,668,223
Ensembl chr 4:94,451,857...94,668,227
JBrowse link
G PDPN podoplanin multiple interactions ISO
EXP
[Disulfiram binds to Copper] which results in increased expression of PDPN protein
[Disulfiram binds to Copper] which results in increased expression of and results in increased phosphorylation of and results in increased ubiquitination of PDPN protein
CTD PMID:24690739 NCBI chr 1:13,583,757...13,617,957
Ensembl chr 1:13,583,465...13,617,957
JBrowse link
G PDRG1 p53 and DNA damage regulated 1 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of PDRG1 mRNA CTD PMID:24690739 NCBI chr20:31,944,337...31,952,046
Ensembl chr20:31,944,337...31,952,046
JBrowse link
G PGD phosphogluconate dehydrogenase increases expression EXP Disulfiram results in increased expression of PGD mRNA CTD PMID:20566472 NCBI chr 1:10,399,064...10,420,511
Ensembl chr 1:10,398,592...10,420,511
JBrowse link
G PHLDA2 pleckstrin homology like domain family A member 2 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of PHLDA2 mRNA CTD PMID:24690739 NCBI chr11:2,928,273...2,929,420
Ensembl chr11:2,928,273...2,929,420
JBrowse link
G PHLDB2 pleckstrin homology like domain family B member 2 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of PHLDB2 mRNA CTD PMID:24690739 NCBI chr 3:111,732,496...111,976,517
Ensembl chr 3:111,732,497...111,976,517
JBrowse link
G PIGQ phosphatidylinositol glycan anchor biosynthesis class Q multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of PIGQ mRNA CTD PMID:24690739 NCBI chr16:569,968...584,109
Ensembl chr16:566,995...584,109
JBrowse link
G PIK3IP1 phosphoinositide-3-kinase interacting protein 1 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of PIK3IP1 mRNA CTD PMID:24690739 NCBI chr22:31,281,593...31,292,534
Ensembl chr22:31,281,594...31,292,534
JBrowse link
G PIN4P1 peptidylprolyl cis/trans isomerase, NIMA-interacting 4 pseudogene 1 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of PIN4P1 mRNA CTD PMID:24690739 NCBI chr15:43,875,806...43,878,171
Ensembl chr15:43,875,849...43,876,244
JBrowse link
G PIP4K2A phosphatidylinositol-5-phosphate 4-kinase type 2 alpha multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of PIP4K2A mRNA CTD PMID:24690739 NCBI chr10:22,534,854...22,714,578
Ensembl chr10:22,534,854...22,714,578
JBrowse link
G PLOD2 procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of PLOD2 mRNA CTD PMID:24690739 NCBI chr 3:146,069,440...146,161,184
Ensembl chr 3:146,035,139...146,163,725
JBrowse link
G PLPBP pyridoxal phosphate binding protein multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of PLPBP mRNA CTD PMID:24690739 NCBI chr 8:37,762,546...37,779,768
Ensembl chr 8:37,762,595...37,779,768
JBrowse link
G PLSCR4 phospholipid scramblase 4 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of PLSCR4 mRNA CTD PMID:24690739 NCBI chr 3:146,192,335...146,251,105
Ensembl chr 3:146,192,335...146,251,179
JBrowse link
G PLXNB2 plexin B2 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of PLXNB2 mRNA CTD PMID:24690739 NCBI chr22:50,274,979...50,307,646
Ensembl chr22:50,274,979...50,307,646
JBrowse link
G PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 increases expression EXP Disulfiram results in increased expression of PMAIP1 mRNA CTD PMID:34182011 NCBI chr18:59,899,996...59,904,305
Ensembl chr18:59,899,996...59,904,305
JBrowse link
G PNLDC1 PARN like ribonuclease domain containing exonuclease 1 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of PNLDC1 mRNA CTD PMID:24690739 NCBI chr 6:159,799,455...159,820,704
Ensembl chr 6:159,800,249...159,820,704
JBrowse link
G PNMA2 PNMA family member 2 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of PNMA2 mRNA CTD PMID:24690739 NCBI chr 8:26,504,701...26,513,872
Ensembl chr 8:26,504,701...26,514,092
JBrowse link
G POLR2C RNA polymerase II subunit C multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of POLR2C mRNA CTD PMID:24690739 NCBI chr16:57,462,679...57,472,009
Ensembl chr16:57,462,660...57,472,009
JBrowse link
G POLR2M RNA polymerase II subunit M multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of POLR2M mRNA CTD PMID:24690739 NCBI chr15:57,706,714...57,717,557
Ensembl chr15:57,706,695...57,782,762
JBrowse link
G POMC proopiomelanocortin decreases expression ISO Disulfiram results in decreased expression of POMC protein alternative form CTD PMID:8246921 NCBI chr 2:25,160,860...25,168,580
Ensembl chr 2:25,160,853...25,168,903
JBrowse link
G POP4 POP4 homolog, ribonuclease P/MRP subunit multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of POP4 mRNA CTD PMID:24690739 NCBI chr19:29,606,283...29,617,237
Ensembl chr19:29,606,283...29,617,237
JBrowse link
G POSTN periostin multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of POSTN mRNA CTD PMID:24690739 NCBI chr13:37,562,585...37,598,768
Ensembl chr13:37,562,583...37,598,844
JBrowse link
G PPARG peroxisome proliferator activated receptor gamma affects expression
multiple interactions
EXP
ISO
Disulfiram affects the expression of PPARG mRNA
Disulfiram binds to and results in increased activity of PPARG protein
CTD PMID:32712770 PMID:33049310 NCBI chr 3:12,287,368...12,434,344
Ensembl chr 3:12,287,368...12,434,356
JBrowse link
G PPIA peptidylprolyl isomerase A multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of PPIA mRNA CTD PMID:24690739 NCBI chr 7:44,796,681...44,803,117
Ensembl chr 7:44,796,680...44,824,564
JBrowse link
G PPP1R15A protein phosphatase 1 regulatory subunit 15A multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of PPP1R15A mRNA CTD PMID:24690739 NCBI chr19:48,872,421...48,876,058
Ensembl chr19:48,872,212...48,876,059
JBrowse link
G PPP1R3C protein phosphatase 1 regulatory subunit 3C multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of PPP1R3C mRNA CTD PMID:24690739 NCBI chr10:91,628,442...91,633,071
Ensembl chr10:91,628,442...91,633,071
JBrowse link
G PPP2R2B protein phosphatase 2 regulatory subunit Bbeta multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of PPP2R2B mRNA CTD PMID:24690739 NCBI chr 5:146,580,742...147,081,520
Ensembl chr 5:146,580,742...147,084,784
JBrowse link
G PRDX1 peroxiredoxin 1 increases expression EXP Disulfiram results in increased expression of PRDX1 mRNA; Disulfiram results in increased expression of PRDX1 protein CTD PMID:34182011 NCBI chr 1:45,511,051...45,522,890
Ensembl chr 1:45,510,914...45,542,732
JBrowse link
G PROK2 prokineticin 2 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of PROK2 mRNA CTD PMID:24690739 NCBI chr 3:71,771,655...71,785,148
Ensembl chr 3:71,771,655...71,785,206
JBrowse link
G PRSS8 serine protease 8 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of PRSS8 mRNA CTD PMID:24690739 NCBI chr16:31,131,433...31,135,727
Ensembl chr16:31,131,433...31,135,727
JBrowse link
G PSAT1 phosphoserine aminotransferase 1 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of PSAT1 mRNA CTD PMID:24690739 NCBI chr 9:78,297,125...78,330,093
Ensembl chr 9:78,297,125...78,330,093
JBrowse link
G PSG11 pregnancy specific beta-1-glycoprotein 11 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of PSG11 mRNA CTD PMID:24690739 NCBI chr19:43,007,656...43,026,469
Ensembl chr19:43,007,656...43,026,474
JBrowse link
G PSG5 pregnancy specific beta-1-glycoprotein 5 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of PSG5 mRNA CTD PMID:24690739 NCBI chr19:43,167,743...43,186,536
Ensembl chr19:43,166,256...43,186,536
JBrowse link
G PSG9 pregnancy specific beta-1-glycoprotein 9 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of PSG9 mRNA CTD PMID:24690739 NCBI chr19:43,253,282...43,269,530
Ensembl chr19:43,211,791...43,269,530
JBrowse link
G PSMC4 proteasome 26S subunit, ATPase 4 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of PSMC4 mRNA CTD PMID:24690739 NCBI chr19:39,971,165...39,981,764
Ensembl chr19:39,971,165...39,981,764
JBrowse link
G PSPN persephin multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of PSPN mRNA CTD PMID:24690739 NCBI chr19:6,375,148...6,375,933
Ensembl chr19:6,375,148...6,379,058
JBrowse link
G PTEN phosphatase and tensin homolog multiple interactions
increases expression
EXP [Copper co-treated with Disulfiram] results in decreased expression of PTEN protein
Disulfiram results in increased expression of PTEN mRNA
CTD PMID:20424113 PMID:34182011 NCBI chr10:87,863,625...87,971,930
Ensembl chr10:87,862,638...87,971,930
JBrowse link
G PTGES3 prostaglandin E synthase 3 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of PTGES3 mRNA CTD PMID:24690739 NCBI chr12:56,663,349...56,688,284
Ensembl chr12:56,663,341...56,688,408
JBrowse link
G PTGR1 prostaglandin reductase 1 increases expression EXP Disulfiram results in increased expression of PTGR1 mRNA CTD PMID:20566472 NCBI chr 9:111,549,722...111,599,647
Ensembl chr 9:111,549,722...111,599,893
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 decreases expression ISO Disulfiram results in decreased expression of PTGS2 mRNA CTD PMID:10418820 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922
JBrowse link
G PTMA prothymosin alpha multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of PTMA mRNA CTD PMID:24690739 NCBI chr 2:231,708,525...231,713,551
Ensembl chr 2:231,706,895...231,713,551
JBrowse link
G PTX3 pentraxin 3 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of PTX3 mRNA CTD PMID:24690739 NCBI chr 3:157,436,850...157,443,633
Ensembl chr 3:157,436,850...157,443,633
JBrowse link
G RAB40A RAB40A, member RAS oncogene family multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of RAB40A mRNA CTD PMID:24690739 NCBI chr  X:103,493,266...103,519,489
Ensembl chr  X:103,499,130...103,519,489
JBrowse link
G RAB5C RAB5C, member RAS oncogene family multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of RAB5C mRNA CTD PMID:24690739 NCBI chr17:42,124,979...42,154,989
Ensembl chr17:42,124,978...42,155,044
JBrowse link
G RAC1 Rac family small GTPase 1 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of RAC1 mRNA CTD PMID:24690739 NCBI chr 7:6,374,527...6,403,967
Ensembl chr 7:6,374,527...6,403,967
JBrowse link
G RAI2 retinoic acid induced 2 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of RAI2 mRNA CTD PMID:24690739 NCBI chr  X:17,800,049...17,861,298
Ensembl chr  X:17,800,049...17,861,337
JBrowse link
G RAMAC RNA guanine-7 methyltransferase activating subunit multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of RAMAC mRNA CTD PMID:24690739 NCBI chr15:82,986,210...82,991,057
Ensembl chr15:82,986,210...82,991,057
JBrowse link
G RASA1 RAS p21 protein activator 1 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of RASA1 mRNA CTD PMID:24690739 NCBI chr 5:87,267,883...87,391,916
Ensembl chr 5:87,267,883...87,391,931
JBrowse link
G RASD1 ras related dexamethasone induced 1 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of RASD1 mRNA CTD PMID:24690739 NCBI chr17:17,494,437...17,496,395
Ensembl chr17:17,494,437...17,496,395
JBrowse link
G RASL11B RAS like family 11 member B multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of RASL11B mRNA CTD PMID:24690739 NCBI chr 4:52,862,317...52,866,835
Ensembl chr 4:52,862,317...52,866,835
JBrowse link
G RBIS ribosomal biogenesis factor multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of RBIS mRNA CTD PMID:24690739 NCBI chr 8:85,214,048...85,220,374
Ensembl chr 8:85,214,048...85,220,421
JBrowse link
G RBM18 RNA binding motif protein 18 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of RBM18 mRNA CTD PMID:24690739 NCBI chr 9:122,237,622...122,264,840
Ensembl chr 9:122,237,622...122,264,840
JBrowse link
G RBM48 RNA binding motif protein 48 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of RBM48 mRNA CTD PMID:24690739 NCBI chr 7:92,528,795...92,540,481
Ensembl chr 7:92,528,773...92,540,481
JBrowse link
G REP15 RAB15 effector protein multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of REP15 mRNA CTD PMID:24690739 NCBI chr12:27,696,447...27,697,596
Ensembl chr12:27,696,447...27,697,596
JBrowse link
G RFTN1 raftlin, lipid raft linker 1 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of RFTN1 mRNA CTD PMID:24690739 NCBI chr 3:16,315,845...16,513,699
Ensembl chr 3:16,313,574...16,514,026
JBrowse link
G RFTN2 raftlin family member 2 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of RFTN2 mRNA CTD PMID:24690739 NCBI chr 2:197,568,224...197,675,587
Ensembl chr 2:197,568,224...197,676,045
JBrowse link
G RGCC regulator of cell cycle multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of RGCC mRNA CTD PMID:24690739 NCBI chr13:41,457,550...41,470,871
Ensembl chr13:41,457,550...41,470,871
JBrowse link
G RGS11 regulator of G protein signaling 11 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of RGS11 mRNA CTD PMID:24690739 NCBI chr16:268,307...275,944
Ensembl chr16:268,301...275,980
JBrowse link
G RGS16 regulator of G protein signaling 16 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of RGS16 mRNA CTD PMID:24690739 NCBI chr 1:182,598,623...182,604,389
Ensembl chr 1:182,598,623...182,604,389
JBrowse link
G RGS2 regulator of G protein signaling 2 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of RGS2 mRNA CTD PMID:24690739 NCBI chr 1:192,809,039...192,812,275
Ensembl chr 1:192,809,039...192,812,275
JBrowse link
G RHBDF1 rhomboid 5 homolog 1 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of RHBDF1 mRNA CTD PMID:24690739 NCBI chr16:58,059...76,360
Ensembl chr16:58,059...76,355
JBrowse link
G RHBDF2 rhomboid 5 homolog 2 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of RHBDF2 mRNA CTD PMID:24690739 NCBI chr17:76,470,893...76,501,427
Ensembl chr17:76,470,891...76,501,790
JBrowse link
G RHOB ras homolog family member B multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of RHOB mRNA CTD PMID:24690739 NCBI chr 2:20,447,074...20,449,440
Ensembl chr 2:20,447,074...20,449,440
JBrowse link
G RNF207 ring finger protein 207 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of RNF207 mRNA CTD PMID:24690739 NCBI chr 1:6,206,119...6,221,299
Ensembl chr 1:6,205,475...6,221,299
JBrowse link
G RPL23 ribosomal protein L23 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of RPL23 mRNA CTD PMID:24690739 NCBI chr17:38,847,860...38,853,721
Ensembl chr17:38,847,860...38,868,644
JBrowse link
G RPL29 ribosomal protein L29 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of RPL29 mRNA CTD PMID:24690739 NCBI chr 3:51,993,522...51,995,895
Ensembl chr 3:51,993,522...51,995,895
JBrowse link
G RPL38 ribosomal protein L38 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of RPL38 mRNA CTD PMID:24690739 NCBI chr17:74,203,678...74,210,655
Ensembl chr17:74,203,582...74,210,655
JBrowse link
G RPLP1 ribosomal protein lateral stalk subunit P1 increases expression EXP Disulfiram results in increased expression of RPLP1 protein CTD PMID:34182011 NCBI chr15:69,452,818...69,456,205
Ensembl chr15:69,452,814...69,456,205
JBrowse link
G RPLP2P3 ribosomal protein lateral stalk subunit P2 pseudogene 3 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of RPLP2P3 mRNA CTD PMID:24690739 NCBI chr11:107,908,347...107,908,802 JBrowse link
G RPS15 ribosomal protein S15 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of RPS15 mRNA CTD PMID:24690739 NCBI chr19:1,438,396...1,440,495
Ensembl chr19:1,438,358...1,440,495
JBrowse link
G RPS26P35 ribosomal protein S26 pseudogene 35 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of RPS26P35 mRNA CTD PMID:24690739 NCBI chr 8:118,761,783...118,762,232
Ensembl chr 8:118,761,856...118,762,201
JBrowse link
G RPS27P29 ribosomal protein S27 pseudogene 29 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of RPS27P29 mRNA CTD PMID:24690739 NCBI chr19:23,597,307...23,597,649
Ensembl chr19:23,597,341...23,597,592
JBrowse link
G RPS7 ribosomal protein S7 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of RPS7 mRNA CTD PMID:24690739 NCBI chr 2:3,575,260...3,580,920
Ensembl chr 2:3,575,260...3,580,920
JBrowse link
G RRAD RRAD, Ras related glycolysis inhibitor and calcium channel regulator multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of RRAD mRNA CTD PMID:24690739 NCBI chr16:66,921,685...66,925,535
Ensembl chr16:66,921,685...66,925,535
JBrowse link
G RRAGD Ras related GTP binding D multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of RRAGD mRNA CTD PMID:24690739 NCBI chr 6:89,364,616...89,412,273
Ensembl chr 6:89,364,616...89,412,273
JBrowse link
G RRAS RAS related multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of RRAS mRNA CTD PMID:24690739 NCBI chr19:49,635,292...49,640,143
Ensembl chr19:49,635,292...49,640,143
JBrowse link
G RSAD2 radical S-adenosyl methionine domain containing 2 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of RSAD2 mRNA CTD PMID:24690739 NCBI chr 2:6,865,885...6,898,239
Ensembl chr 2:6,865,557...6,898,239
JBrowse link
G RUNX2 RUNX family transcription factor 2 increases expression ISO Disulfiram results in increased expression of RUNX2 mRNA CTD PMID:24496638 NCBI chr 6:45,328,330...45,551,082
Ensembl chr 6:45,328,157...45,664,349
JBrowse link
G RYBP RING1 and YY1 binding protein multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of RYBP mRNA CTD PMID:24690739 NCBI chr 3:72,374,597...72,446,623
Ensembl chr 3:72,371,825...72,446,621
JBrowse link
G S100P S100 calcium binding protein P multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of S100P mRNA CTD PMID:24690739 NCBI chr 4:6,693,878...6,697,170
Ensembl chr 4:6,693,878...6,697,170
JBrowse link
G SAP18 Sin3A associated protein 18 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of SAP18 mRNA CTD PMID:24690739 NCBI chr13:21,140,119...21,149,097
Ensembl chr13:21,140,119...21,149,097
JBrowse link
G SAR1B secretion associated Ras related GTPase 1B multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of SAR1B mRNA CTD PMID:24690739 NCBI chr 5:134,601,149...134,632,828
Ensembl chr 5:134,601,149...134,649,271
JBrowse link
G SAT1 spermidine/spermine N1-acetyltransferase 1 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of SAT1 mRNA CTD PMID:24690739 NCBI chr  X:23,783,173...23,786,210
Ensembl chr  X:23,783,173...23,786,210
JBrowse link
G SBDS SBDS ribosome maturation factor multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of SBDS mRNA CTD PMID:24690739 NCBI chr 7:66,987,680...66,995,586
Ensembl chr 7:66,987,680...66,995,693
JBrowse link
G SCARF2 scavenger receptor class F member 2 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of SCARF2 mRNA CTD PMID:24690739 NCBI chr22:20,424,584...20,437,825
Ensembl chr22:20,424,584...20,437,826
JBrowse link
G SCNM1 sodium channel modifier 1 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of SCNM1 mRNA CTD PMID:24690739 NCBI chr 1:151,166,144...151,170,296
Ensembl chr 1:151,156,664...151,170,296
JBrowse link
G SEC61B SEC61 translocon subunit beta multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of SEC61B mRNA CTD PMID:24690739 NCBI chr 9:99,222,282...99,230,615
Ensembl chr 9:99,222,064...99,230,615
JBrowse link
G SEL1L3 SEL1L family member 3 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of SEL1L3 mRNA CTD PMID:24690739 NCBI chr 4:25,713,964...25,863,566
Ensembl chr 4:25,747,433...25,863,760
JBrowse link
G SEM1 SEM1 26S proteasome subunit multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of SEM1 mRNA CTD PMID:24690739 NCBI chr 7:96,481,626...96,709,846
Ensembl chr 7:96,481,626...96,709,880
JBrowse link
G SERTAD1 SERTA domain containing 1 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of SERTAD1 mRNA CTD PMID:24690739 NCBI chr19:40,421,589...40,425,992
Ensembl chr19:40,421,589...40,425,992
JBrowse link
G SF3B4 splicing factor 3b subunit 4 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of SF3B4 mRNA CTD PMID:24690739 NCBI chr 1:149,923,317...149,927,803
Ensembl chr 1:149,923,317...149,927,803
JBrowse link
G SGTA small glutamine rich tetratricopeptide repeat co-chaperone alpha multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of SGTA mRNA CTD PMID:24690739 NCBI chr19:2,754,715...2,783,273
Ensembl chr19:2,754,715...2,783,362
JBrowse link
G SH3PXD2A SH3 and PX domains 2A multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of SH3PXD2A mRNA CTD PMID:24690739 NCBI chr10:103,594,027...103,855,576
Ensembl chr10:103,594,027...103,855,584
JBrowse link
G SIK1 salt inducible kinase 1 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of SIK1 mRNA CTD PMID:24690739 NCBI chr21:43,414,483...43,427,131
Ensembl chr21:43,414,483...43,427,131
JBrowse link
G SIRT1 sirtuin 1 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of SIRT1 mRNA CTD PMID:24690739 NCBI chr10:67,884,656...67,918,390
Ensembl chr10:67,884,656...67,918,390
JBrowse link
G SIRT6 sirtuin 6 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of SIRT6 mRNA CTD PMID:24690739 NCBI chr19:4,174,109...4,182,563
Ensembl chr19:4,174,109...4,182,566
JBrowse link
G SKI SKI proto-oncogene multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of SKI mRNA CTD PMID:24690739 NCBI chr 1:2,228,319...2,310,213
Ensembl chr 1:2,227,388...2,310,213
JBrowse link
G SKIL SKI like proto-oncogene multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of SKIL mRNA CTD PMID:24690739 NCBI chr 3:170,357,715...170,396,849
Ensembl chr 3:170,357,342...170,396,835
JBrowse link
G SLC16A10 solute carrier family 16 member 10 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of SLC16A10 mRNA CTD PMID:24690739 NCBI chr 6:111,087,503...111,231,194
Ensembl chr 6:111,087,503...111,231,194
JBrowse link
G SLC25A37 solute carrier family 25 member 37 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of SLC25A37 mRNA CTD PMID:24690739 NCBI chr 8:23,528,956...23,575,463
Ensembl chr 8:23,528,956...23,575,463
JBrowse link
G SLC30A1 solute carrier family 30 member 1 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of SLC30A1 mRNA CTD PMID:24690739 NCBI chr 1:211,571,568...211,579,161
Ensembl chr 1:211,571,568...211,579,161
JBrowse link
G SLC44A1 solute carrier family 44 member 1 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of SLC44A1 mRNA CTD PMID:24690739 NCBI chr 9:105,244,651...105,438,504
Ensembl chr 9:105,244,622...105,439,171
JBrowse link
G SLC44A2 solute carrier family 44 member 2 (CTL2 blood group) multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of SLC44A2 mRNA CTD PMID:24690739 NCBI chr19:10,602,455...10,644,557
Ensembl chr19:10,602,457...10,644,557
JBrowse link
G SLC6A9 solute carrier family 6 member 9 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of SLC6A9 mRNA CTD PMID:24690739 NCBI chr 1:43,996,483...44,031,462
Ensembl chr 1:43,991,500...44,031,467
JBrowse link
G SLC7A1 solute carrier family 7 member 1 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of SLC7A1 mRNA CTD PMID:24690739 NCBI chr13:29,509,414...29,595,688
Ensembl chr13:29,509,414...29,595,688
JBrowse link
G SLC7A6OS solute carrier family 7 member 6 opposite strand multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of SLC7A6OS mRNA CTD PMID:24690739 NCBI chr16:68,298,034...68,310,946
Ensembl chr16:68,284,503...68,310,946
JBrowse link
G SLFN11 schlafen family member 11 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of SLFN11 mRNA CTD PMID:24690739 NCBI chr17:35,350,305...35,373,621
Ensembl chr17:35,350,305...35,373,701
JBrowse link
G SLU7 SLU7 homolog, splicing factor multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of SLU7 mRNA CTD PMID:24690739 NCBI chr 5:160,401,641...160,419,081
Ensembl chr 5:160,401,641...160,421,711
JBrowse link
G SMAD3 SMAD family member 3 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of SMAD3 mRNA CTD PMID:24690739 NCBI chr15:67,065,602...67,195,169
Ensembl chr15:67,063,763...67,195,173
JBrowse link
G SMOX spermine oxidase multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of SMOX mRNA CTD PMID:24690739 NCBI chr20:4,148,828...4,187,727
Ensembl chr20:4,120,980...4,187,747
JBrowse link
G SNAI1 snail family transcriptional repressor 1 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of SNAI1 mRNA CTD PMID:24690739 NCBI chr20:49,982,980...49,988,886
Ensembl chr20:49,982,980...49,988,886
JBrowse link
G SNAR-A1 small NF90 (ILF3) associated RNA A1 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of SNAR-A1 mRNA CTD PMID:24690739 NCBI chr19:47,918,429...47,918,550 JBrowse link
G SNIP1 Smad nuclear interacting protein 1 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of SNIP1 mRNA CTD PMID:24690739 NCBI chr 1:37,534,449...37,554,293
Ensembl chr 1:37,534,449...37,554,293
JBrowse link
G SNORA70 small nucleolar RNA, H/ACA box 70 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of SNORA70 mRNA CTD PMID:24690739 NCBI chr  X:154,400,281...154,400,415
Ensembl chr  X:154,400,281...154,400,415
JBrowse link
G SNRPB2 small nuclear ribonucleoprotein polypeptide B2 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of SNRPB2 mRNA CTD PMID:24690739 NCBI chr20:16,730,026...16,742,564
Ensembl chr20:16,729,961...16,742,564
JBrowse link
G SOD1 superoxide dismutase 1 increases expression
decreases activity
EXP
ISO
Disulfiram results in increased expression of SOD1 mRNA
Disulfiram results in decreased activity of SOD1 protein
CTD PMID:19016906 PMID:20566472 NCBI chr21:31,659,693...31,668,931
Ensembl chr21:31,659,666...31,668,931
JBrowse link
G SOD2 superoxide dismutase 2 increases expression
multiple interactions
EXP Disulfiram results in increased expression of SOD2 mRNA
[Disulfiram co-treated with Zinc Sulfate] results in increased expression of SOD2 mRNA
CTD PMID:20566472 PMID:32712770 PMID:34182011 NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529
JBrowse link
G SOD3 superoxide dismutase 3 increases expression EXP Disulfiram results in increased expression of SOD3 mRNA CTD PMID:20566472 NCBI chr 4:24,795,573...24,800,842
Ensembl chr 4:24,789,912...24,800,842
JBrowse link
G SOX8 SRY-box transcription factor 8 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of SOX8 mRNA CTD PMID:24690739 NCBI chr16:981,770...986,979
Ensembl chr16:981,444...986,979
JBrowse link
G SPACDR sperm acrosome developmental regulator multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of SPACDR mRNA CTD PMID:24690739 NCBI chr 7:100,456,620...100,464,260
Ensembl chr 7:100,456,620...100,464,260
JBrowse link
G SPANXN1 SPANX family member N1 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of SPANXN1 mRNA CTD PMID:24690739 NCBI chr  X:145,247,503...145,256,208
Ensembl chr  X:145,247,503...145,256,208
JBrowse link
G SPANXN5 SPANX family member N5 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of SPANXN5 mRNA CTD PMID:24690739 NCBI chr  X:52,796,144...52,797,427
Ensembl chr  X:52,796,144...52,797,427
JBrowse link
G SPATA20 spermatogenesis associated 20 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of SPATA20 mRNA CTD PMID:24690739 NCBI chr17:50,547,174...50,555,852
Ensembl chr17:50,543,058...50,555,852
JBrowse link
G SPG7 SPG7 matrix AAA peptidase subunit, paraplegin multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of SPG7 mRNA CTD PMID:24690739 NCBI chr16:89,508,388...89,557,768
Ensembl chr16:89,490,719...89,557,766
JBrowse link
G SPIRE1 spire type actin nucleation factor 1 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of SPIRE1 mRNA CTD PMID:24690739 NCBI chr18:12,446,512...12,662,091
Ensembl chr18:12,446,512...12,658,107
JBrowse link
G SPSB1 splA/ryanodine receptor domain and SOCS box containing 1 increases expression EXP Disulfiram results in increased expression of SPSB1 mRNA CTD PMID:20566472 NCBI chr 1:9,292,894...9,369,532
Ensembl chr 1:9,292,894...9,369,532
JBrowse link
G SPTBN1 spectrin beta, non-erythrocytic 1 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of SPTBN1 mRNA CTD PMID:24690739 NCBI chr 2:54,456,327...54,671,446
Ensembl chr 2:54,456,327...54,671,446
JBrowse link
G SPTY2D1 SPT2 chromatin protein domain containing 1 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of SPTY2D1 mRNA CTD PMID:24690739 NCBI chr11:18,606,403...18,634,342
Ensembl chr11:18,606,403...18,634,791
JBrowse link
G SQSTM1 sequestosome 1 decreases expression EXP Disulfiram results in decreased expression of SQSTM1 protein CTD PMID:34182011 NCBI chr 5:179,806,393...179,838,078
Ensembl chr 5:179,806,398...179,838,078
JBrowse link
G SREBF1 sterol regulatory element binding transcription factor 1 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of SREBF1 mRNA CTD PMID:24690739 NCBI chr17:17,811,334...17,836,986
Ensembl chr17:17,810,399...17,837,002
JBrowse link
G SRXN1 sulfiredoxin 1 increases expression EXP Disulfiram results in increased expression of SRXN1 mRNA CTD PMID:20566472 NCBI chr20:646,615...653,200
Ensembl chr20:646,615...653,200
JBrowse link
G SSX3 SSX family member 3 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of SSX3 mRNA CTD PMID:24690739 NCBI chr  X:48,346,427...48,356,703
Ensembl chr  X:48,346,427...48,356,707
JBrowse link
G STC2 stanniocalcin 2 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of STC2 mRNA CTD PMID:24690739 NCBI chr 5:173,314,723...173,328,414
Ensembl chr 5:173,314,723...173,328,447
JBrowse link
G STEEP1 STING1 ER exit protein 1 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of STEEP1 mRNA CTD PMID:24690739 NCBI chr  X:119,538,149...119,565,409
Ensembl chr  X:119,538,149...119,565,409
JBrowse link
G STX3 syntaxin 3 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of STX3 mRNA CTD PMID:24690739 NCBI chr11:59,754,188...59,805,878
Ensembl chr11:59,713,456...59,805,882
JBrowse link
G SULF1 sulfatase 1 multiple interactions EXP
ISO
[Disulfiram binds to Copper] which results in increased expression of SULF1 mRNA; [Disulfiram binds to Copper] which results in increased expression of SULF1 protein CTD PMID:24690739 NCBI chr 8:69,466,781...69,660,912
Ensembl chr 8:69,466,624...69,660,915
JBrowse link
G SUMO2 small ubiquitin like modifier 2 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of SUMO2 mRNA CTD PMID:24690739 NCBI chr17:75,165,586...75,182,959
Ensembl chr17:75,165,586...75,182,959
JBrowse link
G SUN1 Sad1 and UNC84 domain containing 1 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of SUN1 mRNA CTD PMID:24690739 NCBI chr 7:815,557...874,934
Ensembl chr 7:816,615...896,435
JBrowse link
G SUN2 Sad1 and UNC84 domain containing 2 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of SUN2 mRNA CTD PMID:24690739 NCBI chr22:38,734,734...38,755,998
Ensembl chr22:38,733,290...38,794,143
JBrowse link
G SUPT4H1 SPT4 homolog, DSIF elongation factor subunit multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of SUPT4H1 mRNA CTD PMID:24690739 NCBI chr17:58,345,178...58,352,201
Ensembl chr17:58,345,175...58,353,093
JBrowse link
G SYNJ1 synaptojanin 1 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of SYNJ1 mRNA CTD PMID:24690739 NCBI chr21:32,628,759...32,728,394
Ensembl chr21:32,628,759...32,728,040
JBrowse link
G SZRD1 SUZ RNA binding domain containing 1 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of SZRD1 mRNA CTD PMID:24690739 NCBI chr 1:16,367,242...16,398,145
Ensembl chr 1:16,352,575...16,398,145
JBrowse link
G TAF13 TATA-box binding protein associated factor 13 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of TAF13 mRNA CTD PMID:24690739 NCBI chr 1:109,064,140...109,076,003
Ensembl chr 1:109,062,496...109,076,012
JBrowse link
G TAF7 TATA-box binding protein associated factor 7 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of TAF7 mRNA CTD PMID:24690739 NCBI chr 5:141,318,490...141,320,784
Ensembl chr 5:141,259,884...141,320,784
JBrowse link
G TAMALIN trafficking regulator and scaffold protein tamalin multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of TAMALIN mRNA CTD PMID:24690739 NCBI chr12:52,006,946...52,015,889
Ensembl chr12:52,006,946...52,015,889
JBrowse link
G TANC1 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of TANC1 mRNA CTD PMID:24690739 NCBI chr 2:158,968,640...159,232,659
Ensembl chr 2:158,968,640...159,232,659
JBrowse link
G TAP2 transporter 2, ATP binding cassette subfamily B member multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of TAP2 mRNA CTD PMID:24690739 NCBI chr 6:32,821,831...32,838,739
Ensembl chr 6:32,821,833...32,838,739
JBrowse link
G TAPBP TAP binding protein multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of TAPBP mRNA CTD PMID:24690739 NCBI chr 6:33,299,694...33,314,078
Ensembl chr 6:33,299,694...33,314,284
JBrowse link
G TAT tyrosine aminotransferase multiple interactions ISO [Ethanol co-treated with Disulfiram] results in increased activity of TAT protein CTD PMID:9591243 NCBI chr16:71,565,660...71,577,092
Ensembl chr16:71,565,660...71,577,092
JBrowse link
G TCEA2 transcription elongation factor A2 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of TCEA2 mRNA CTD PMID:24690739 NCBI chr20:64,055,596...64,072,347
Ensembl chr20:64,049,836...64,072,347
JBrowse link
G TCP1 t-complex 1 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of TCP1 mRNA CTD PMID:24690739 NCBI chr 6:159,778,498...159,789,602
Ensembl chr 6:159,778,498...159,789,703
JBrowse link
G TENT5B terminal nucleotidyltransferase 5B multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of TENT5B mRNA CTD PMID:24690739 NCBI chr 1:27,005,020...27,012,850
Ensembl chr 1:27,005,020...27,012,850
JBrowse link
G TENT5C terminal nucleotidyltransferase 5C multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of TENT5C mRNA CTD PMID:24690739 NCBI chr 1:117,606,048...117,628,389
Ensembl chr 1:117,606,048...117,628,389
JBrowse link
G TFIP11 tuftelin interacting protein 11 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of TFIP11 mRNA CTD PMID:24690739 NCBI chr22:26,491,240...26,512,473
Ensembl chr22:26,491,225...26,512,505
JBrowse link
G TGFB1 transforming growth factor beta 1 decreases activity EXP Disulfiram results in decreased activity of TGFB1 protein CTD PMID:31652400 NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922
JBrowse link
G THAP1 THAP domain containing 1 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of THAP1 mRNA CTD PMID:24690739 NCBI chr 8:42,836,674...42,843,325
Ensembl chr 8:42,836,674...42,843,325
JBrowse link
G THEM6 thioesterase superfamily member 6 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of THEM6 mRNA CTD PMID:24690739 NCBI chr 8:142,727,223...142,736,927
Ensembl chr 8:142,727,223...142,736,927
JBrowse link
G THRA thyroid hormone receptor alpha multiple interactions EXP Disulfiram binds to and results in increased activity of THRA protein CTD PMID:33049310 NCBI chr17:40,062,193...40,093,867
Ensembl chr17:40,058,290...40,093,867
JBrowse link
G TICAM2 TIR domain containing adaptor molecule 2 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of TICAM2 mRNA CTD PMID:24690739 NCBI chr 5:115,578,496...115,602,479
Ensembl chr 5:115,578,496...115,602,479
JBrowse link
G TMEM167A transmembrane protein 167A multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of TMEM167A mRNA CTD PMID:24690739 NCBI chr 5:83,052,846...83,077,394
Ensembl chr 5:83,052,846...83,077,863
JBrowse link
G TMEM175 transmembrane protein 175 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of TMEM175 mRNA CTD PMID:24690739 NCBI chr 4:932,460...958,656
Ensembl chr 4:932,387...958,656
JBrowse link
G TMEM208 transmembrane protein 208 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of TMEM208 mRNA CTD PMID:24690739 NCBI chr16:67,227,130...67,229,278
Ensembl chr16:67,227,103...67,229,278
JBrowse link
G TMEM35B transmembrane protein 35B multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of TMEM35B mRNA CTD PMID:24690739 NCBI chr 1:34,981,380...34,985,347
Ensembl chr 1:34,981,380...34,985,347
JBrowse link
G TMEM42 transmembrane protein 42 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of TMEM42 mRNA CTD PMID:24690739 NCBI chr 3:44,861,912...44,865,664
Ensembl chr 3:44,861,904...44,865,670
JBrowse link
G TMEM43 transmembrane protein 43 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of TMEM43 mRNA CTD PMID:24690739 NCBI chr 3:14,125,052...14,143,680
Ensembl chr 3:14,125,015...14,143,680
JBrowse link
G TMEM44 transmembrane protein 44 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of TMEM44 mRNA CTD PMID:24690739 NCBI chr 3:194,587,678...194,633,419
Ensembl chr 3:194,587,673...194,633,689
JBrowse link
G TNF tumor necrosis factor decreases expression
multiple interactions
increases secretion
ISO
EXP
Disulfiram results in decreased expression of TNF mRNA
[Disulfiram co-treated with Zinc Sulfate] inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]; Disulfiram inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of TNF protein]; Disulfiram promotes the reaction [Lipopolysaccharides results in increased secretion of TNF protein]
Disulfiram results in increased secretion of TNF protein
Disulfiram inhibits the reaction [[CCL5 protein binds to and results in increased activity of CCR5 protein] which results in increased secretion of TNF protein]
CTD PMID:10418820 PMID:19016906 PMID:32712770 PMID:33851234 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
JBrowse link
G TNFRSF6B TNF receptor superfamily member 6b multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of TNFRSF6B mRNA CTD PMID:24690739 NCBI chr20:63,696,652...63,698,684
Ensembl chr20:63,696,652...63,698,684
JBrowse link
G TNFSF10 TNF superfamily member 10 increases expression EXP Disulfiram results in increased expression of TNFSF10 mRNA CTD PMID:34182011 NCBI chr 3:172,505,508...172,523,430
Ensembl chr 3:172,505,508...172,523,475
JBrowse link
G TNIP1 TNFAIP3 interacting protein 1 multiple interactions ISO
EXP
[Disulfiram binds to Copper] which results in increased expression of TNIP1 protein CTD PMID:24690739 NCBI chr 5:151,029,943...151,087,685
Ensembl chr 5:151,029,945...151,093,577
JBrowse link
G TNIP2 TNFAIP3 interacting protein 2 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of TNIP2 protein CTD PMID:24690739 NCBI chr 4:2,741,648...2,756,336
Ensembl chr 4:2,741,648...2,756,342
JBrowse link
G TNS3 tensin 3 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of TNS3 mRNA CTD PMID:24690739 NCBI chr 7:47,275,154...47,582,586
Ensembl chr 7:47,275,154...47,582,558
JBrowse link
G TPRKB TP53RK binding protein multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of TPRKB mRNA CTD PMID:24690739 NCBI chr 2:73,729,873...73,737,345
Ensembl chr 2:73,729,104...73,737,400
JBrowse link
G TPSAB1 tryptase alpha/beta 1 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of TPSAB1 mRNA CTD PMID:24690739 NCBI chr16:1,240,705...1,242,554
Ensembl chr16:1,239,266...1,242,554
JBrowse link
G TRA2B transformer 2 beta homolog multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of TRA2B mRNA CTD PMID:24690739 NCBI chr 3:185,914,558...185,938,014
Ensembl chr 3:185,914,558...185,938,103
JBrowse link
G TRABD TraB domain containing multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of TRABD mRNA CTD PMID:24690739 NCBI chr22:50,185,913...50,199,595
Ensembl chr22:50,185,913...50,199,598
JBrowse link
G TRH thyrotropin releasing hormone multiple interactions
increases expression
decreases expression
ISO Dexamethasone promotes the reaction [Disulfiram results in decreased expression of TRH protein]
Disulfiram results in increased expression of TRH mRNA alternative form
CTD PMID:9681491 NCBI chr 3:129,974,720...129,977,935
Ensembl chr 3:129,974,688...129,977,935
JBrowse link
G TSHB thyroid stimulating hormone subunit beta multiple interactions
decreases secretion
ISO Dexamethasone promotes the reaction [Disulfiram results in decreased secretion of TSHB protein] CTD PMID:9681491 NCBI chr 1:115,029,826...115,034,309
Ensembl chr 1:115,029,826...115,034,302
JBrowse link
G TSPYL2 TSPY like 2 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of TSPYL2 mRNA CTD PMID:24690739 NCBI chr  X:53,082,367...53,088,540
Ensembl chr  X:53,082,367...53,088,540
JBrowse link
G TTC13 tetratricopeptide repeat domain 13 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of TTC13 mRNA CTD PMID:24690739 NCBI chr 1:230,906,243...230,978,861
Ensembl chr 1:230,906,243...230,978,875
JBrowse link
G TTF1 transcription termination factor 1 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of TTF1 mRNA CTD PMID:24690739 NCBI chr 9:132,375,548...132,406,840
Ensembl chr 9:132,375,548...132,406,851
JBrowse link
G TUBA4A tubulin alpha 4a multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of TUBA4A mRNA CTD PMID:24690739 NCBI chr 2:219,249,710...219,254,740
Ensembl chr 2:219,249,710...219,277,902
JBrowse link
G TUBB2A tubulin beta 2A class IIa multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of TUBB2A mRNA CTD PMID:24690739 NCBI chr 6:3,153,666...3,157,544
Ensembl chr 6:3,153,497...3,157,544
JBrowse link
G TUBB2B tubulin beta 2B class IIb multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of TUBB2B mRNA CTD PMID:24690739 NCBI chr 6:3,224,277...3,227,653
Ensembl chr 6:3,223,324...3,231,730
JBrowse link
G TUBB3 tubulin beta 3 class III multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of TUBB3 mRNA CTD PMID:24690739 NCBI chr16:89,921,925...89,936,097
Ensembl chr16:89,921,392...89,938,761
JBrowse link
G TUBB7P tubulin beta 7 pseudogene multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of TUBB7P mRNA CTD PMID:24690739 NCBI chr 4:189,982,335...189,984,929
Ensembl chr 4:189,982,523...189,984,871
JBrowse link
G TXN2 thioredoxin 2 increases expression EXP Disulfiram results in increased expression of TXN2 mRNA CTD PMID:20566472 NCBI chr22:36,467,046...36,481,640
Ensembl chr22:36,467,046...36,481,640
JBrowse link
G TXNL1 thioredoxin like 1 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of TXNL1 mRNA CTD PMID:24690739 NCBI chr18:56,597,209...56,638,592
Ensembl chr18:56,597,209...56,651,600
JBrowse link
G TXNRD1 thioredoxin reductase 1 increases expression EXP Disulfiram results in increased expression of TXNRD1 mRNA CTD PMID:20566472 NCBI chr12:104,215,779...104,350,307
Ensembl chr12:104,215,779...104,350,307
JBrowse link
G TXNRD2 thioredoxin reductase 2 increases expression EXP Disulfiram results in increased expression of TXNRD2 mRNA CTD PMID:20566472 NCBI chr22:19,875,522...19,941,818
Ensembl chr22:19,875,517...19,941,820
JBrowse link
G UBFD1 ubiquitin family domain containing 1 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of UBFD1 mRNA CTD PMID:24690739 NCBI chr16:23,557,727...23,574,389
Ensembl chr16:23,557,721...23,574,389
JBrowse link
G UGT1A6 UDP glucuronosyltransferase family 1 member A6 increases expression EXP Disulfiram results in increased expression of UGT1A6 mRNA CTD PMID:20566472 NCBI chr 2:233,691,702...233,773,300
Ensembl chr 2:233,691,607...233,773,300
JBrowse link
G ULK1 unc-51 like autophagy activating kinase 1 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of ULK1 mRNA CTD PMID:24690739 NCBI chr12:131,894,622...131,923,150
Ensembl chr12:131,894,622...131,923,150
JBrowse link
G UQCC4 ubiquinol-cytochrome c reductase complex assembly factor 4 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of UQCC4 mRNA CTD PMID:24690739 NCBI chr16:1,419,752...1,420,747
Ensembl chr16:1,419,752...1,420,756
JBrowse link
G UQCRB ubiquinol-cytochrome c reductase binding protein multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of UQCRB mRNA CTD PMID:24690739 NCBI chr 8:96,222,947...96,235,545
Ensembl chr 8:96,222,947...96,235,546
JBrowse link
G UQCRH ubiquinol-cytochrome c reductase hinge protein multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of UQCRH mRNA CTD PMID:24690739 NCBI chr 1:46,303,698...46,316,776
Ensembl chr 1:46,303,698...46,316,776
JBrowse link
G USP17L30 ubiquitin specific peptidase 17 like family member 30 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of USP17L30 mRNA CTD PMID:24690739 NCBI chr 4:9,363,129...9,364,721
Ensembl chr 4:9,363,129...9,364,721
JBrowse link
G USPL1 ubiquitin specific peptidase like 1 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of USPL1 mRNA CTD PMID:24690739 NCBI chr13:30,617,920...30,660,766
Ensembl chr13:30,617,693...30,660,770
JBrowse link
G UTP11 UTP11 small subunit processome component multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of UTP11 mRNA CTD PMID:24690739 NCBI chr 1:38,012,734...38,024,820
Ensembl chr 1:38,009,258...38,024,820
JBrowse link
G UTP3 UTP3 small subunit processome component multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of UTP3 mRNA CTD PMID:24690739 NCBI chr 4:70,688,532...70,690,551
Ensembl chr 4:70,688,532...70,690,551
JBrowse link
G VCAN versican multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of VCAN mRNA CTD PMID:24690739 NCBI chr 5:83,471,744...83,582,302
Ensembl chr 5:83,471,618...83,582,303
JBrowse link
G VCL vinculin multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of VCL mRNA CTD PMID:24690739 NCBI chr10:73,998,116...74,121,363
Ensembl chr10:73,995,193...74,121,363
JBrowse link
G VDAC1 voltage dependent anion channel 1 multiple interactions EXP VDAC1 protein results in increased susceptibility to [arsenic trioxide co-treated with Ascorbic Acid co-treated with Disulfiram] CTD PMID:24126434 NCBI chr 5:133,971,871...134,114,540
Ensembl chr 5:133,971,871...134,004,975
JBrowse link
G VEGFC vascular endothelial growth factor C multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of VEGFC mRNA CTD PMID:24690739 NCBI chr 4:176,683,538...176,792,922
Ensembl chr 4:176,683,538...176,792,922
JBrowse link
G VGF VGF nerve growth factor inducible multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of VGF mRNA CTD PMID:24690739 NCBI chr 7:101,162,509...101,169,952
Ensembl chr 7:101,162,509...101,165,569
JBrowse link
G VIM vimentin multiple interactions EXP
ISO
[Disulfiram binds to Copper] which results in increased cleavage of VIM protein CTD PMID:24690739 NCBI chr10:17,228,241...17,237,593
Ensembl chr10:17,228,241...17,237,593
JBrowse link
G VPS37B VPS37B subunit of ESCRT-I multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of VPS37B mRNA CTD PMID:24690739 NCBI chr12:122,865,330...122,896,124
Ensembl chr12:122,865,330...122,896,127
JBrowse link
G WDR20 WD repeat domain 20 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of WDR20 mRNA CTD PMID:24690739 NCBI chr14:102,139,423...102,224,839
Ensembl chr14:102,139,503...102,224,847
JBrowse link
G XYLT2 xylosyltransferase 2 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of XYLT2 mRNA CTD PMID:24690739 NCBI chr17:50,346,126...50,361,185
Ensembl chr17:50,346,126...50,363,138
JBrowse link
G YJU2 YJU2 splicing factor homolog multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of YJU2 mRNA CTD PMID:24690739 NCBI chr19:4,247,080...4,269,088
Ensembl chr19:4,247,080...4,269,088
JBrowse link
G ZBTB43 zinc finger and BTB domain containing 43 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of ZBTB43 mRNA CTD PMID:24690739 NCBI chr 9:126,804,072...126,838,210
Ensembl chr 9:126,805,006...126,838,210
JBrowse link
G ZFAND2A zinc finger AN1-type containing 2A multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of ZFAND2A mRNA CTD PMID:24690739 NCBI chr 7:1,148,850...1,160,196
Ensembl chr 7:1,151,903...1,160,759
JBrowse link
G ZFP36 ZFP36 ring finger protein multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of ZFP36 mRNA CTD PMID:24690739 NCBI chr19:39,406,847...39,409,407
Ensembl chr19:39,406,847...39,409,407
JBrowse link
G ZHX3 zinc fingers and homeoboxes 3 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of ZHX3 mRNA CTD PMID:24690739 NCBI chr20:41,178,455...41,317,731
Ensembl chr20:41,178,448...41,317,731
JBrowse link
G ZKSCAN5 zinc finger with KRAB and SCAN domains 5 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of ZKSCAN5 mRNA CTD PMID:24690739 NCBI chr 7:99,504,662...99,534,700
Ensembl chr 7:99,504,662...99,534,700
JBrowse link
G ZMAT2 zinc finger matrin-type 2 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of ZMAT2 mRNA CTD PMID:24690739 NCBI chr 5:140,700,447...140,706,686
Ensembl chr 5:140,698,680...140,706,686
JBrowse link
G ZMAT5 zinc finger matrin-type 5 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of ZMAT5 mRNA CTD PMID:24690739 NCBI chr22:29,730,956...29,767,007
Ensembl chr22:29,730,956...29,767,011
JBrowse link
G ZNF143 zinc finger protein 143 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of ZNF143 mRNA CTD PMID:24690739 NCBI chr11:9,461,012...9,528,524
Ensembl chr11:9,460,319...9,528,524
JBrowse link
G ZNF20 zinc finger protein 20 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of ZNF20 mRNA CTD PMID:24690739 NCBI chr19:12,131,350...12,140,350
Ensembl chr19:12,092,843...12,140,355
JBrowse link
G ZNF217 zinc finger protein 217 multiple interactions EXP [Disulfiram binds to Copper] which results in increased expression of ZNF217 mRNA CTD PMID:24690739 NCBI chr20:53,567,071...53,597,702
Ensembl chr20:53,567,071...53,609,907
JBrowse link
G ZNF34 zinc finger protein 34 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of ZNF34 mRNA CTD PMID:24690739 NCBI chr 8:144,772,224...144,787,317
Ensembl chr 8:144,772,224...144,787,348
JBrowse link
G ZNF35 zinc finger protein 35 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of ZNF35 mRNA CTD PMID:24690739 NCBI chr 3:44,646,506...44,660,791
Ensembl chr 3:44,648,732...44,660,791
JBrowse link
G ZNF408 zinc finger protein 408 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of ZNF408 mRNA CTD PMID:24690739 NCBI chr11:46,701,031...46,705,912
Ensembl chr11:46,701,030...46,705,912
JBrowse link
G ZNF622 zinc finger protein 622 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of ZNF622 mRNA CTD PMID:24690739 NCBI chr 5:16,451,519...16,465,800
Ensembl chr 5:16,451,519...16,465,800
JBrowse link
G ZNF77 zinc finger protein 77 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of ZNF77 mRNA CTD PMID:24690739 NCBI chr19:2,933,218...2,944,971
Ensembl chr19:2,933,218...2,944,971
JBrowse link
G ZNF778 zinc finger protein 778 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of ZNF778 mRNA CTD PMID:24690739 NCBI chr16:89,217,703...89,237,141
Ensembl chr16:89,217,703...89,237,141
JBrowse link
G ZSCAN26 zinc finger and SCAN domain containing 26 multiple interactions EXP [Disulfiram binds to Copper] which results in decreased expression of ZSCAN26 mRNA CTD PMID:24690739 NCBI chr 6:28,267,143...28,278,204
Ensembl chr 6:28,267,058...28,278,224
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 26504
    role 26326
      biological role 26305
        inhibitor 22569
          NF-kappaB inhibitor 2498
            disulfiram 660
Path 2
Term Annotations click to browse term
  CHEBI ontology 26504
    subatomic particle 26480
      composite particle 26480
        hadron 26480
          baryon 26480
            nucleon 26480
              atomic nucleus 26480
                atom 26480
                  main group element atom 26217
                    p-block element atom 26217
                      carbon group element atom 25660
                        carbon atom 25622
                          organic molecular entity 25622
                            heteroorganic entity 25005
                              organochalcogen compound 24601
                                organosulfur compound 19879
                                  organosulfur pesticide 712
                                    organosulfur acaricide 661
                                      disulfiram 660
paths to the root