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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:protein kinase inhibitor
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Accession:CHEBI:37699 term browser browse the term
Definition:An EC 2.7.* (P-containing group transferase) inhibitor that interferes with the action of protein kinases.
Synonyms:related_synonym: protein kinase inhibitors
 alt_id: MESH:D047428
 xref_mesh: MESH:D047428


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      CHEBI ontology 22298
        role 22264
          biological role 22281
            biochemical role 21501
              enzyme inhibitor 19924
                EC 2.* (transferase) inhibitor 15338
                  EC 2.7.* (P-containing group transferase) inhibitor 14764
                    protein kinase inhibitor 14322
                      (+)-makassaric acid 0
                      (+)-subersic acid 0
                      1,4-diamino-2,3-dicyano-1,4-bis(phenylthio)butadiene 0
                      1,8-dihydroxy-4-nitroxanthen-9-one 0
                      2-(\{2-[(3-hydroxyphenyl)amino]pyrimidin-4-yl\}amino)benzamide 0
                      Aurora kinase inhibitor + 4355
                      CMB4563 0
                      CZC8004 0
                      DMH1 0
                      EC 2.7.10.* (protein-tyrosine kinase) inhibitor + 10018
                      EC 2.7.11.* (protein-serine/threonine kinase) inhibitor + 10265
                      EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor + 1335
                      Ro 320-1195 + 0
                      SAR-AD81 0
                      XMD8-92 0
                      aminopurvalanol 0
                      epidermal growth factor receptor antagonist + 343
                      erlotinib + 135
                      erlotinib hydrochloride 135
                      gamma-mangostin 0
                      mTOR inhibitor + 543
                      miltefosine 2
                      pelitinib + 0
                      piceatannol + 11
                      purvalanol B 0
                      quercetin + 4352
                      salt-inducible kinase 2 inhibitor + 0
                      sangivamycin 0
                      tyrosine kinase inhibitor + 12100
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