|
.0 |
.0 |
.003 |
.001 |
.0 |
.019 |
.002 |
.0 |
.006 |
.054 |
.001 |
.004 |
.0 |
.19 |
.837 |
.057 |
.951 |
.015 |
.023 |
.077 |
.001 |
.021 |
.0 |
.59 |
.092 |
.003 |
.491 |
.001 |
.002 |
.015 |
.001 |
.007 |
.179 |
.126 |
.02 |
.002 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
.004 |
.001 |
.02 |
.354 |
.003 |
.001 |
.0 |
.001 |
.12 |
.107 |
.06 |
.208 |
.006 |
.03 |
.014 |
.001 |
.006 |
.012 |
.0 |
.001 |
.0 |
.006 |
.001 |
.0 |
.011 |
.002 |
.001 |
.001 |
.002 |
.24 |
.002 |
.352 |
.002 |
.16 |
.121 |
.057 |
.002 |
.001 |
.003 |
.139 |
.002 |
.004 |
.002 |
.0 |
.009 |
.92 |
.004 |
.008 |
.003 |
.015 |
.011 |
.132 |
.901 |
.71 |
.008 |
.06 |
-- |
.88 |
.844 |
.0 |
.109 |
.001 |
-- |
-- |
.059 |
-- |
.04 |
.043 |
.009 |
.023 |
-- |
.001 |
.893 |
.445 |
.234 |
.113 |
.006 |
.005 |
.169 |
.073 |
.076 |
.003 |
.144 |
.068 |
.169 |
.162 |
.003 |
.01 |
.022 |
.005 |
.145 |
.168 |
.072 |
.145 |
.043 |
.043 |
.003 |
.0 |
.034 |
.07 |
.471 |
.048 |
.014 |
.01 |
.0 |
.0 |
.0 |
.0 |
.0 |
.512 |
.47 |
.097 |
.308 |
.003 |
.006 |
.001 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
.001 |
.003 |
.005 |
.007 |
.005 |
.006 |
.005 |
.003 |
.002 |
.001 |
.001 |
.002 |
.007 |
.014 |
.007 |
.0 |
.297 |
.0 |
.002 |
.253 |
.991 |
.383 |
.008 |
.04 |
.002 |
.017 |
.086 |
.253 |
.207 |
.183 |
.072 |
.238 |
-- |
-- |
-- |
.228 |
.852 |
.009 |
.016 |
.009 |
.021 |
.099 |
.912 |
.0 |
.012 |
.036 |
.005 |
.003 |
.001 |
.003 |
.004 |
.001 |
.947 |
.945 |
.156 |
-- |
-- |
.014 |
.008 |
.003 |
.001 |
.003 |
.029 |
.02 |
.002 |
.0 |
.006 |
.006 |
.001 |
.016 |
.016 |
.0 |
-- |
-- |
-- |
-- |
.0 |
.001 |
.004 |
.137 |
-- |
-- |
.096 |
.001 |
.099 |
.062 |
.019 |
.017 |
-- |
.49 |
.027 |
.005 |
.005 |
.257 |
.004 |
.002 |
.0 |
.001 |
.049 |
.003 |
.002 |
.0 |
.0 |
.002 |
.004 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
.04 |
.044 |
.132 |
.026 |
.002 |
.003 |
.059 |
.065 |
.022 |
.001 |
-- |
-- |
-- |
-- |
.145 |
.009 |
.061 |
.018 |
.008 |
.045 |
.003 |
.194 |
.0 |
.0 |
.001 |
.002 |
|
Tox2
|
Tox2
|
Tox2
|
Tox2
|
Tox2
|
Tox2
|
Tox2
|
Tox2
|
Tox2
|
Tox2
|
Tox2
|
Tox2
|
Tox2
|
Tox2
|
Tox2
|
Tox2
|
Tox2
|
Tox2
|
Tox2
|
Tox2
|
Tox2
|
Tox2
|
Tox2
|
Tox2
|
Tox2
|
Tox2
|
Tox2
|
Tox2
|
Tox2
|
Tox2
|
Tox2
|
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
|
T |
C |
C |
C |
C |
G |
T |
T |
A |
G |
C |
T |
T |
G |
C |
T |
C |
A |
C |
G |
A |
C |
T |
G |
G |
T |
6 |
G |
T |
C |
C |
G |
G |
C |
G |
T |
A |
G |
20 |
G |
G |
2 |
G |
C |
C |
A |
C |
A |
G |
A |
C |
A |
G |
C |
G |
A |
G |
T |
A |
C |
T |
A |
G |
A |
G |
C |
T |
4 |
G |
T |
C |
T |
T |
C |
T |
G |
3 |
G |
T |
G |
C |
A |
A |
T |
C |
A |
C |
G |
C |
C |
2 |
C |
C |
A |
C |
A |
C |
A |
T |
G |
2 |
C |
T |
A |
A |
G |
C |
T |
G |
A |
C |
C |
G |
A |
C |
A |
G |
T |
G |
T |
T |
T |
T |
T |
A |
G |
T |
C |
C |
T |
C |
G |
T |
2 |
2 |
G |
A |
C |
T |
C |
C |
T |
A |
T |
C |
C |
C |
A |
T |
T |
G |
G |
A |
A |
A |
T |
A |
T |
G |
2 |
C |
A |
C |
T |
T |
T |
A |
A |
C |
C |
C |
A |
T |
T |
T |
A |
A |
A |
A |
G |
T |
T |
T |
G |
T |
T |
8 |
G |
T |
G |
A |
T |
16 |
C |
A |
G |
C |
A |
G |
2 |
A |
C |
A |
C |
G |
C |
A |
C |
A |
G |
T |
G |
G |
12 |
T |
T |
A |
A |
T |
C |
G |
A |
A |
C |
C |
C |
C |
A |
T |
T |
G |
G |
G |
T |
G |
T |
A |
G |
T |
C |
A |
T |
G |
C |
C |
C |
C |
T |
C |
G |
T |
G |
T |
2 |
T |
G |
G |
T |
C |
C |
A |
A |
C |
C |
A |
A |
G |
G |
T |
C |
T |
2 |
G |
C |
C |
C |
A |
C |
A |
A |
G |
C |
C |
T |
T |
A |
T |
G |
C |
C |
T |
G |
C |
G |
C |
C |
C |
G |
T |
T |
T |
T |
C |
A |
A |
A |
A |
T |
T |
T |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
G
|
G
|
G
|
T
|
T
|
G/5
|
C
|
C
|
G
|
A
|
-
|
C
|
C
|
C
|
G
|
C
|
4
|
T
|
T
|
G/2
|
G
|
T
|
C
|
A
|
-
|
C
|
-
|
A
|
2
|
-
|
T
|
-
|
A
|
T
|
2
|
C
|
3
|
A
|
-
|
G/A
|
G/A
|
-
|
A
|
G
|
3
|
G
|
-
|
C
|
5
|
G
|
-
|
T
|
2
|
T
|
A
|
G
|
G/A
|
C
|
G
|
T
|
C
|
C
|
A
|
C
|
C
|
T
|
C
|
-
|
T
|
2
|
T
|
C
|
C
|
A
|
C
|
A
|
-
|
C
|
C
|
A
|
T
|
G
|
G
|
2
|
T
|
A/3
|
T
|
A
|
C/2
|
T
|
-
|
T
|
T
|
G
|
C/T
|
A/G
|
T
|
-
|
C
|
2
|
-
|
T
|
C
|
5
|
T
|
A
|
T
|
C
|
A
|
G
|
T
|
T
|
T
|
A/3
|
T
|
T
|
T
|
C
|
2
|
C
|
C
|
C
|
C
|
C
|
G
|
T
|
C
|
T
|
A
|
C
|
A
|
T
|
C
|
-
|
2/-
|
C
|
C
|
6/4
|
-
|
G
|
T
|
C
|
C
|
-
|
T
|
T
|
T
|
G
|
C
|
C
|
A
|
A
|
A/-
|
A/G
|
G
|
C
|
G
|
C
|
G/A
|
-
|
G
|
T
|
A
|
C
|
A
|
A
|
C
|
T
|
A
|
T
|
T
|
T
|
C
|
A
|
G
|
C
|
C
|
C
|
T
|
T
|
C
|
C
|
-
|
C
|
C
|
C
|
-
|
9
|
C
|
A
|
G
|
C
|
16/-
|
2
|
-
|
2
|
T
|
G
|
-
|
-
|
G
|
T
|
G
|
T
|
3
|
4
|
G
|
T
|
G
|
A
|
C
|
C
|
A
|
-
|
C
|
C
|
2
|
G
|
C
|
A
|
A
|
2
|
-
|
4
|
T
|
T
|
T
|
C
|
C
|
C
|
A
|
A
|
A
|
2
|
A
|
-
|
3
|
A
|
C
|
5
|
C
|
-
|
-
|
T
|
G
|
-
|
C/4
|
T/C
|
5
|
T
|
-
|
T
|
2
|
-
|
-
|
A
|
A
|
C
|
T
|
G
|
G
|
-
|
G
|
T
|
G
|
G
|
15
|
A
|
A
|
T
|
C
|
-
|
T
|
G
|
T
|
A
|
G
|
A
|
G
|
G
|
A
|
CT/3
|
C/T
|
G
|
G
|
C
|
C
|
2
|
T
|
T
|
C
|
A
|
G
|
T
|
C/T
|
C/G
|
C/T
|
A
|
C
|
C
|
C
|
C
|
T
|
G
|
G
|
G
|
G
|
2
|
C
|
13
|
|