|
-- |
-- |
-- |
.15 |
.008 |
.028 |
.035 |
.06 |
.013 |
.011 |
.013 |
.264 |
-- |
.007 |
.012 |
.043 |
.122 |
.136 |
.024 |
.025 |
.064 |
.099 |
.034 |
.015 |
.181 |
.286 |
.015 |
.091 |
-- |
-- |
.024 |
.082 |
.03 |
.101 |
.05 |
.039 |
.008 |
.011 |
.114 |
.034 |
.06 |
.091 |
.216 |
.004 |
.019 |
.106 |
.003 |
.003 |
.213 |
.246 |
.057 |
.063 |
.023 |
.159 |
.036 |
.093 |
.394 |
.019 |
.004 |
.329 |
.067 |
-- |
-- |
.222 |
.01 |
.079 |
.534 |
.009 |
-- |
-- |
.003 |
.002 |
.008 |
.048 |
.0 |
.055 |
.0 |
.099 |
.0 |
.151 |
.052 |
.133 |
.038 |
.05 |
.058 |
.053 |
.041 |
.026 |
.014 |
.005 |
.032 |
.236 |
.054 |
.007 |
.038 |
.0 |
1.0 |
.001 |
.008 |
.001 |
.083 |
.031 |
.15 |
.001 |
.981 |
.001 |
.014 |
.035 |
.006 |
.0 |
.0 |
.003 |
.001 |
.001 |
.015 |
.02 |
.006 |
.146 |
.001 |
-- |
.471 |
.007 |
.067 |
.006 |
.302 |
.958 |
-- |
-- |
.0 |
.191 |
.138 |
.605 |
.058 |
.058 |
-- |
.192 |
.0 |
.991 |
.001 |
.21 |
.028 |
.002 |
.0 |
.001 |
.0 |
.0 |
.874 |
.713 |
.135 |
.995 |
.173 |
.0 |
.05 |
.015 |
.936 |
.016 |
.969 |
.643 |
.564 |
.002 |
.0 |
.011 |
.124 |
.161 |
.004 |
.013 |
.065 |
.008 |
.48 |
.029 |
.042 |
.01 |
.008 |
.017 |
.003 |
.001 |
.001 |
.001 |
.0 |
.001 |
.0 |
.006 |
-- |
-- |
.006 |
.06 |
.013 |
.008 |
.111 |
.009 |
-- |
-- |
.064 |
.278 |
.029 |
.014 |
-- |
-- |
-- |
.041 |
.013 |
.0 |
.001 |
.01 |
.004 |
.046 |
-- |
-- |
-- |
.005 |
.079 |
-- |
-- |
-- |
.147 |
.107 |
.102 |
.023 |
.017 |
.0 |
.0 |
-- |
-- |
.017 |
.0 |
.997 |
.197 |
.066 |
-- |
-- |
.006 |
.098 |
.022 |
.001 |
.047 |
.029 |
.002 |
1.0 |
.481 |
.0 |
.076 |
-- |
.006 |
.006 |
.838 |
.007 |
.103 |
.43 |
.398 |
.341 |
.202 |
.183 |
.251 |
.624 |
.772 |
.888 |
.11 |
.055 |
.015 |
.015 |
.004 |
.005 |
.019 |
.012 |
.007 |
.034 |
.015 |
.018 |
.059 |
.005 |
.005 |
.01 |
.016 |
.011 |
.027 |
.002 |
-- |
-- |
-- |
.116 |
.006 |
.008 |
.004 |
.087 |
.014 |
.044 |
.11 |
.375 |
.002 |
.004 |
.003 |
.014 |
.015 |
.128 |
.035 |
.014 |
.012 |
.009 |
.001 |
.002 |
.023 |
.003 |
-- |
-- |
-- |
-- |
-- |
.037 |
.071 |
.069 |
.006 |
.304 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
.011 |
.003 |
.003 |
.002 |
.001 |
.005 |
.0 |
.0 |
.004 |
.001 |
.003 |
.0 |
.055 |
.618 |
.272 |
.017 |
.551 |
.005 |
.402 |
.005 |
.042 |
.0 |
.636 |
.046 |
.0 |
.005 |
.014 |
.045 |
.015 |
.006 |
.113 |
.0 |
.002 |
.004 |
.0 |
.509 |
.0 |
.0 |
.999 |
-- |
-- |
-- |
.004 |
.005 |
.002 |
.001 |
.021 |
.017 |
.115 |
.035 |
.008 |
.0 |
.032 |
.002 |
.041 |
.006 |
.001 |
.001 |
.0 |
.0 |
.015 |
.0 |
.001 |
.0 |
.001 |
.016 |
.0 |
.041 |
.006 |
.0 |
.022 |
.0 |
.002 |
.002 |
.004 |
.001 |
.001 |
.005 |
.407 |
.035 |
.281 |
.002 |
.001 |
.0 |
.0 |
.0 |
.042 |
-- |
.004 |
.0 |
.0 |
.0 |
.21 |
.14 |
-- |
.065 |
.137 |
.846 |
.008 |
-- |
-- |
.082 |
.04 |
.015 |
.098 |
.041 |
.027 |
.0 |
.046 |
-- |
.035 |
.027 |
-- |
-- |
-- |
.0 |
.299 |
.0 |
.026 |
.004 |
.923 |
.96 |
.014 |
.0 |
.007 |
.004 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
.086 |
.756 |
-- |
-- |
-- |
.027 |
.002 |
-- |
-- |
-- |
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
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|
--
|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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--
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--
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--
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--
|
--
|
--
|
Notch4
|
Notch4
|
Notch4
|
Notch4
|
Notch4
|
Notch4
|
Notch4
|
--
|
--
|
--
|
Pbx2
|
Ager
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
Agpat1
|
Agpat1
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
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|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
Fkbpl
|
--
|
--
|
--
|
--
|
Atf6b
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
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|
--
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--
|
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|
--
|
--
|
|
Stk19-ps
|
--
|
--
|
--
|
--
|
--
|
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|
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--
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|
--
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--
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--
|
--
|
--
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--
|
--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
|
--
|
--
|
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|
--
|
--
|
--
|
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|
--
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--
|
--
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--
|
--
|
--
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|
--
|
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|
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|
--
|
--
|
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|
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|
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|
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|
--
|
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|
--
|
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|
--
|
--
|
--
|
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|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
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|
--
|
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|
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|
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|
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|
--
|
--
|
--
|
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|
--
|
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|
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|
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|
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|
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|
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|
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|
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|
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|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
Rnf5
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
Egfl8
|
Ppt2
|
Ppt2
|
Ppt2
|
--
|
--
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--
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--
|
--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
|
--
|
--
|
--
|
--
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--
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--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
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--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
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--
|
--
|
--
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--
|
--
|
--
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--
|
--
|
--
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--
|
--
|
--
|
--
|
--
|
--
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--
|
--
|
--
|
--
|
--
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--
|
--
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--
|
--
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--
|
--
|
--
|
--
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--
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--
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--
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--
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--
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--
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--
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--
|
--
|
--
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--
|
--
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--
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--
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--
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--
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--
|
--
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--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
Cyp21a1
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
|
Stk19
|
Stk19
|
Stk19
|
Stk19
|
Stk19
|
Stk19
|
Stk19
|
Stk19
|
Stk19
|
Stk19
|
Stk19
|
Stk19
|
Stk19
|
Stk19
|
Stk19
|
Stk19
|
Stk19
|
Stk19
|
Stk19
|
Stk19
|
Stk19
|
Stk19
|
Stk19
|
Stk19
|
Stk19
|
Stk19
|
Stk19
|
Stk19
|
Stk19
|
Stk19
|
Stk19
|
Stk19
|
Stk19
|
Stk19
|
Stk19
|
Stk19
|
Stk19
|
Stk19
|
Stk19
|
Stk19
|
Stk19
|
Stk19
|
Stk19
|
Stk19
|
Stk19
|
Stk19
|
Stk19
|
|
C |
A |
C |
T |
G |
T |
C |
A |
G |
T |
T |
A |
C |
C |
A |
A |
C |
C |
C |
A |
A |
T |
C |
A |
A |
C |
C |
C |
G |
G |
A |
C |
G |
G |
G |
G |
G |
T |
T |
6 |
T |
T |
C |
A |
G |
A |
7 |
A |
G |
C |
C |
A |
C |
A |
33 |
G |
T |
G |
C |
C |
22 |
T |
A |
A |
A |
G |
C |
A |
C |
G |
C |
A |
6 |
T |
A |
A |
13 |
T |
T |
G |
G |
C |
T |
T |
A |
A |
G |
G |
G |
G |
A |
G |
G |
A |
C |
G |
A |
A |
G |
G |
A |
T |
A |
C |
C |
T |
G |
T |
C |
C |
T |
G |
A |
A |
G |
A |
G |
A |
T |
153 |
A |
C |
C |
A |
T |
T |
C |
C |
A |
C |
C |
C |
G |
G |
14 |
C |
C |
G |
C |
C |
G |
T |
A |
C |
C |
C |
C |
3 |
A |
C |
A |
A |
G |
T |
3 |
G |
G |
2 |
A |
T |
T |
C |
C |
2 |
G |
4 |
127 |
T |
C |
T |
G |
T |
T |
G |
T |
G |
11 |
C |
C |
C |
G |
C |
T |
A |
6 |
A |
C |
A |
G |
C |
T |
T |
6 |
3 |
2 |
A |
2 |
T |
2 |
C |
8 |
T |
C |
A |
C |
C |
G |
2 |
T |
G |
C |
T |
C |
C |
G |
G |
2 |
C |
T |
2 |
A |
G |
2 |
A |
G |
C |
G |
G |
G |
G |
C |
T |
C |
C |
G |
T |
C |
A |
A |
G |
T |
T |
T |
A |
C |
3 |
G |
A |
G |
G |
C |
A |
A |
G |
C |
G |
G |
A |
C |
A |
T |
C |
2 |
12 |
A |
C |
C |
T |
A |
C |
C |
G |
C |
A |
G |
G |
2 |
G |
2 |
A |
C |
A |
T |
C |
G |
G |
C |
A |
C |
T |
G |
C |
A |
G |
G |
A |
A |
T |
G |
A |
C |
C |
A |
G |
T |
G |
A |
G |
G |
A |
T |
C |
T |
G |
C |
G |
G |
C |
G |
T |
T |
A |
T |
A |
A |
A |
A |
A |
T |
G |
C |
C |
G |
G |
A |
C |
A |
C |
A |
C |
G |
A |
G |
T |
A |
C |
C |
T |
G |
C |
G |
C |
A |
A |
T |
G |
2 |
15 |
T |
G |
G |
T |
A |
G |
C |
6 |
A |
C |
A |
C |
G |
C |
T |
C |
A |
C |
C |
T |
A |
2 |
2 |
T |
T |
G |
T |
C |
8 |
T |
C |
C |
A |
T |
C |
A |
C |
C |
A |
A |
G |
C |
C |
3 |
A |
C |
G |
T |
T |
T |
A |
A |
A |
C |
A |
A |
T |
A |
C |
C |
A |
C |
T |
G |
G |
A |
T |
G |
2 |
19 |
T |
4 |
G |
G |
G |
G |
T |
T |
T |
T |
A |
C |
T |
G |
C |
G |
C |
C |
2 |
G |
G |
A |
4 |
A |
2 |
2 |
A |
C |
C |
C |
T |
10 |
8 |
A |
A |
2 |
T |
A |
G |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
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|
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|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
T
|
G
|
5
|
C
|
T
|
A
|
T
|
G
|
T
|
A
|
C
|
G
|
T
|
T
|
3
|
7
|
T
|
T
|
T
|
G
|
G
|
3
|
T
|
G
|
G
|
T
|
G
|
T
|
A
|
A
|
G
|
T
|
A
|
A
|
A
|
A
|
C
|
C
|
C
|
-
|
C
|
C
|
G
|
G
|
C
|
C
|
-
|
9
|
A
|
T
|
G
|
G
|
T
|
G
|
-
|
A
|
C
|
A
|
T
|
G
|
-
|
A
|
C
|
G
|
3
|
A
|
T
|
2
|
C/T
|
2
|
T
|
G
|
-
|
C
|
G
|
G
|
-
|
A
|
C
|
A
|
A
|
50
|
C
|
C
|
G
|
-
|
A
|
A
|
C
|
C
|
G
|
A
|
-
|
G
|
T
|
A
|
G
|
G
|
A
|
A
|
2
|
C
|
11
|
C/3
|
T
|
C
|
5
|
C
|
G
|
T
|
G
|
T
|
C
|
T
|
A
|
G
|
A
|
T
|
G
|
-
|
G
|
T
|
2
|
G
|
7
|
5
|
T
|
6
|
G
|
-
|
26
|
?
|
2
|
16
|
-
|
G
|
2
|
T
|
T
|
T
|
A
|
C
|
C
|
T
|
T
|
T
|
CT/3
|
-
|
G
|
A
|
G
|
G
|
C
|
C
|
-
|
A
|
A
|
2/-
|
A/-
|
11
|
14
|
4
|
8
|
-
|
A
|
-
|
-
|
C
|
A
|
A
|
A
|
C
|
C
|
A
|
C
|
45
|
-
|
T
|
T
|
T
|
C
|
T
|
C
|
G
|
-
|
G
|
T
|
G
|
5
|
A
|
4
|
A
|
-
|
3/-
|
2/-
|
-
|
2/-
|
T/97
|
-
|
C/2
|
-
|
C
|
T
|
-
|
3/CT
|
CA/3
|
A
|
2/-
|
C
|
2
|
T
|
2
|
C/2
|
C/2
|
A
|
3/GA
|
2/-
|
C/2
|
T/-
|
2/-
|
-
|
3/7
|
2/-
|
G
|
A
|
T
|
3
|
A
|
A
|
A
|
T
|
C
|
T
|
T
|
A
|
C
|
A
|
-
|
3
|
G/-
|
C
|
5
|
G
|
C
|
A
|
-
|
A
|
G
|
4
|
A
|
T
|
G
|
G
|
A
|
T
|
A
|
A
|
9
|
T
|
G
|
C
|
T
|
-
|
-
|
G
|
T
|
T
|
G
|
G
|
T
|
G
|
A
|
T
|
G
|
A
|
T
|
-
|
9
|
2/-
|
G
|
T
|
G
|
C
|
T
|
A
|
T
|
T
|
C
|
T
|
C
|
A
|
T
|
G
|
A
|
2
|
G
|
G
|
G
|
A
|
G
|
T
|
14
|
G
|
C
|
C
|
T
|
G
|
3
|
A
|
97
|
C
|
T
|
C
|
A
|
T
|
A
|
5
|
T
|
A
|
A
|
G
|
G
|
C
|
G
|
T
|
G
|
G
|
2
|
103
|
A
|
2
|
T
|
A
|
20
|
C
|
A
|
G
|
T
|
G
|
A
|
C
|
C
|
C
|
C
|
G
|
T
|
T
|
G
|
T
|
T
|
A
|
-
|
T
|
G
|
4
|
G/-
|
-
|
-
|
C
|
A
|
A
|
C
|
G
|
A
|
G
|
-
|
G
|
A
|
G
|
3
|
C
|
G
|
C
|
5
|
T
|
A
|
T
|
G
|
G
|
-
|
-
|
5
|
C
|
A
|
A
|
T
|
-
|
C
|
T
|
T
|
G
|
C
|
G
|
C
|
T
|
T
|
C
|
T
|
A
|
T
|
A
|
-
|
G
|
T
|
A
|
C
|
C
|
A
|
G
|
G
|
G
|
T
|
3
|
A/2
|
C
|
C
|
T
|
T
|
T
|
T
|
A
|
A
|
C
|
-
|
2
|
A
|
2/-
|
-
|
C
|
-
|
T
|
A
|
A
|
A
|
-
|
-
|
A
|
A
|
A/-
|
13
|
53
|
-
|
2
|
3
|
G
|
T
|
2/-
|
G/-
|
G/31
|
A/73
|
4/-
|
A/5
|
2/-
|
2/-
|
A/3
|
C/3
|
C/5
|
T
|
C
|
10/-
|
8/-
|
T
|
-
|
-
|
G
|
G
|
2
|
|