|
.064 |
.013 |
-- |
.001 |
.46 |
.002 |
-- |
.084 |
.019 |
.0 |
.001 |
.002 |
.061 |
.295 |
.001 |
.001 |
.0 |
.002 |
.0 |
.0 |
.007 |
.022 |
.817 |
.737 |
.936 |
.921 |
.876 |
.787 |
.018 |
.001 |
.001 |
.024 |
.497 |
.0 |
.121 |
.032 |
.007 |
.014 |
.0 |
.0 |
.001 |
.57 |
.103 |
.019 |
.226 |
.282 |
.004 |
.011 |
.339 |
.01 |
.01 |
.004 |
.003 |
.012 |
.2 |
.002 |
.03 |
.004 |
.003 |
.132 |
.035 |
.105 |
.996 |
.274 |
.985 |
.013 |
-- |
.06 |
.012 |
.069 |
.002 |
.0 |
.025 |
.001 |
.007 |
.097 |
.425 |
.002 |
.012 |
.046 |
.016 |
.004 |
.011 |
.001 |
.001 |
.001 |
.042 |
.091 |
.003 |
.048 |
.021 |
.0 |
.0 |
.005 |
.012 |
.008 |
.026 |
.007 |
.0 |
.012 |
.026 |
.0 |
.0 |
.714 |
.0 |
.0 |
.0 |
.0 |
.0 |
.758 |
.002 |
.0 |
.002 |
.016 |
.01 |
.0 |
.021 |
.952 |
.018 |
.001 |
.002 |
.102 |
.981 |
.0 |
.004 |
.001 |
.002 |
.033 |
.006 |
.002 |
.625 |
.0 |
.096 |
.09 |
.067 |
.084 |
.003 |
.241 |
.005 |
.001 |
.861 |
.944 |
.002 |
.006 |
-- |
-- |
-- |
.956 |
.071 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
.002 |
.148 |
.662 |
.08 |
.001 |
.164 |
.005 |
.053 |
.012 |
.004 |
.022 |
.231 |
.031 |
.153 |
.118 |
.004 |
.012 |
.001 |
.054 |
.023 |
.639 |
.002 |
-- |
-- |
-- |
.012 |
-- |
-- |
-- |
.031 |
.008 |
.22 |
.001 |
.023 |
.294 |
.023 |
.01 |
.008 |
.357 |
.032 |
.008 |
.0 |
.003 |
.018 |
.0 |
.002 |
.02 |
.0 |
.08 |
.01 |
-- |
.001 |
.003 |
.008 |
.029 |
.024 |
.142 |
.0 |
.0 |
.0 |
.0 |
.002 |
.061 |
.089 |
.001 |
.97 |
.004 |
.004 |
.039 |
.044 |
-- |
.094 |
.012 |
.008 |
.035 |
.001 |
.001 |
-- |
-- |
-- |
-- |
-- |
-- |
.04 |
.088 |
.023 |
.009 |
.111 |
.0 |
.197 |
.275 |
.001 |
.0 |
.039 |
.051 |
.174 |
.106 |
.186 |
.257 |
.302 |
.126 |
.018 |
.008 |
.559 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
.014 |
.002 |
.008 |
.001 |
.002 |
.001 |
.012 |
.004 |
.043 |
.003 |
.01 |
.013 |
.004 |
.111 |
.006 |
.349 |
.049 |
.086 |
.004 |
.002 |
.0 |
.109 |
.096 |
.0 |
.012 |
.001 |
-- |
.559 |
.411 |
.093 |
.048 |
.004 |
.081 |
.022 |
.018 |
.072 |
.001 |
.017 |
.0 |
.0 |
.001 |
.016 |
.0 |
.001 |
.0 |
.001 |
.001 |
.001 |
.069 |
.025 |
.002 |
.03 |
.058 |
.195 |
.23 |
.039 |
.023 |
.057 |
.056 |
.002 |
.025 |
.029 |
.003 |
.055 |
.018 |
.01 |
.01 |
.168 |
.011 |
.011 |
.004 |
.532 |
.001 |
.004 |
.068 |
.027 |
.2 |
.16 |
.025 |
.062 |
.038 |
.138 |
.474 |
.088 |
.313 |
.037 |
.011 |
.003 |
.001 |
.081 |
.099 |
.325 |
.076 |
.152 |
.035 |
.009 |
.002 |
.002 |
.049 |
.028 |
.006 |
.12 |
.024 |
.02 |
.409 |
-- |
-- |
-- |
-- |
-- |
-- |
.053 |
.068 |
.009 |
.013 |
.005 |
.086 |
-- |
-- |
-- |
.086 |
.007 |
.019 |
.011 |
.007 |
.306 |
.324 |
.057 |
.125 |
.119 |
.309 |
.001 |
.187 |
.034 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
.003 |
.001 |
.003 |
.038 |
.006 |
.407 |
.281 |
-- |
-- |
-- |
.987 |
.994 |
-- |
-- |
.007 |
.03 |
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
Angpt2
|
Angpt2
|
Angpt2
|
Angpt2
|
Angpt2
|
Angpt2
|
Angpt2
|
Angpt2
|
Angpt2
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
|
Mcph1
|
Mcph1
|
Mcph1
|
Mcph1
|
Mcph1
|
Mcph1
|
Mcph1
|
Mcph1
|
Mcph1
|
Mcph1
|
Mcph1
|
Mcph1
|
Mcph1
|
Mcph1
|
Mcph1
|
Mcph1
|
Mcph1
|
Mcph1
|
Mcph1
|
Mcph1
|
Mcph1
|
Mcph1
|
Mcph1
|
Mcph1
|
Mcph1
|
Mcph1
|
Mcph1
|
Mcph1
|
Mcph1
|
Mcph1
|
Mcph1
|
Mcph1
|
Mcph1
|
Mcph1
|
Mcph1
|
Mcph1
|
Mcph1
|
Mcph1
|
Mcph1
|
Mcph1
|
Mcph1
|
Mcph1
|
Mcph1
|
|
C |
T |
18 |
G |
A |
T |
C |
G |
T |
C |
A |
T |
A |
A |
C |
T |
C |
G |
G |
G |
T |
C |
A |
T |
G |
G |
2 |
52 |
A |
T |
C |
T |
T |
2 |
G |
G |
T |
A |
C |
C |
A |
A |
G |
C |
T |
C |
G |
T |
A |
G |
C |
G |
A |
A |
C |
A |
A |
C |
C |
C |
G |
A |
8 |
C |
T |
A |
G |
A |
A |
C |
3 |
A |
G |
G |
C |
A |
A |
G |
T |
22 |
T |
A |
T |
C |
T |
C |
T |
C |
A |
T |
A |
10 |
T |
C |
C |
C |
T |
C |
T |
A |
A |
C |
A |
A |
C |
G |
G |
C |
G |
C |
A |
C |
C |
12 |
12 |
C |
A |
4 |
G |
A |
G |
T |
A |
A |
T |
C |
12 |
5 |
A |
C |
C |
T |
4 |
C |
C |
G |
A |
T |
C |
C |
G |
C |
T |
G |
T |
C |
T |
A |
A |
C |
A |
C |
T |
T |
4 |
T |
G |
G |
C |
C |
A |
C |
C |
T |
G |
G |
G |
T |
T |
G |
T |
G |
C |
A |
G |
7 |
T |
G |
A |
T |
C |
C |
C |
C |
4 |
4 |
C |
G |
T |
T |
G |
C |
G |
G |
C |
A |
C |
G |
G |
T |
G |
G |
G |
G |
4 |
A |
T |
G |
T |
A |
A |
T |
T |
T |
T |
T |
A |
A |
C |
2 |
8 |
C |
A |
T |
G |
G |
G |
G |
A |
A |
T |
C |
C |
T |
G |
T |
C |
A |
G |
G |
2 |
G |
C |
A |
A |
G |
5 |
T |
T |
C |
C |
C |
C |
G |
5 |
C |
A |
T |
G |
T |
A |
6 |
A |
T |
G |
G |
G |
G |
A |
G |
G |
C |
C |
A |
G |
C |
C |
T |
C |
C |
C |
C |
T |
G |
T |
C |
G |
G |
A |
T |
A |
G |
12 |
A |
A |
A |
T |
G |
2 |
C |
A |
C |
A |
T |
C |
C |
G |
G |
T |
C |
A |
C |
A |
2 |
G |
T |
C |
A |
C |
T |
A |
G |
T |
T |
C |
G |
C |
G |
C |
T |
G |
A |
9 |
G |
T |
G |
G |
A |
C |
C |
6 |
A |
A |
C |
C |
A |
T |
G |
A |
G |
T |
8 |
T |
A |
C |
T |
C |
G |
C |
A |
G |
C |
T |
T |
A |
G |
G |
G |
A |
26 |
A |
C |
T |
A |
A |
T |
8 |
117 |
G |
A |
T |
T |
A |
C |
C |
C |
A |
A |
T |
C |
C |
T |
G |
A |
T |
A |
T |
T |
G |
C |
A |
C |
C |
G |
C |
8 |
A |
T |
A |
T |
G |
T |
G |
A |
A |
C |
C |
C |
A |
A |
6 |
4 |
G |
A |
A |
T |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
G
|
C
|
-
|
A
|
-
|
C
|
T
|
C
|
C
|
T
|
G
|
C
|
G
|
G
|
T
|
2
|
A
|
A
|
T
|
A
|
-
|
T
|
G
|
A
|
G/A
|
T
|
-
|
-
|
-
|
C
|
T
|
C
|
A
|
2/-
|
A
|
A
|
2
|
C
|
G
|
T
|
C
|
G
|
T
|
T
|
C
|
T
|
A
|
-
|
T
|
A
|
T
|
-
|
G
|
G
|
T
|
G
|
G
|
T
|
G
|
G
|
C
|
C
|
-
|
G
|
A
|
T
|
T
|
T
|
T
|
T
|
-
|
G
|
A
|
A
|
T
|
G
|
G
|
A
|
C
|
22/-
|
C
|
G
|
-
|
T
|
C
|
G
|
A
|
T
|
G
|
C
|
G
|
-
|
C
|
T
|
T
|
?
|
C
|
3
|
-
|
2
|
G
|
T
|
G
|
3
|
T
|
A
|
A
|
9/13
|
G/7
|
T
|
G
|
T
|
T
|
-
|
-
|
T
|
G
|
-
|
A
|
-
|
A
|
TA/3
|
5
|
G
|
5
|
T
|
-
|
-
|
G
|
T
|
T
|
C
|
-
|
3/CA
|
2
|
A
|
2
|
2
|
T
|
T
|
2
|
A
|
2
|
7/6
|
4
|
T
|
C
|
G
|
T
|
T
|
T
|
T
|
C
|
2
|
-
|
G
|
A
|
A
|
G
|
A
|
G
|
5/4
|
T
|
17
|
A
|
C
|
A
|
C
|
G
|
A
|
C
|
T
|
T
|
G
|
?
|
-
|
C
|
2
|
C
|
C
|
T
|
T
|
T
|
3
|
-
|
-
|
T
|
A
|
2
|
C
|
T
|
T
|
C
|
C
|
T
|
-
|
T
|
A
|
A
|
T/5
|
A
|
A
|
A
|
A
|
4/-
|
4
|
C
|
T
|
C
|
T
|
C
|
C
|
C
|
C
|
C
|
C
|
G
|
G
|
T
|
-
|
8/-
|
T
|
2
|
C
|
A
|
C
|
A
|
5
|
-
|
-
|
C
|
T
|
G
|
G
|
A
|
G
|
T
|
G
|
A
|
A
|
-
|
A
|
T
|
G
|
G
|
A
|
-
|
C
|
C
|
T
|
5
|
G
|
T
|
A
|
-
|
4
|
3
|
C
|
T
|
9
|
6
|
-
|
4
|
C
|
10
|
28
|
16
|
A
|
G
|
A
|
A
|
T
|
T
|
G
|
A
|
T
|
T
|
C
|
T
|
G
|
2
|
G
|
C
|
A
|
C
|
A
|
A
|
A
|
G
|
A
|
G
|
A
|
-
|
G
|
G
|
T
|
C
|
G/188
|
-
|
T
|
G
|
T
|
C
|
C
|
2
|
T
|
A
|
C
|
C
|
T
|
G
|
T
|
G
|
-
|
A
|
C
|
T
|
G
|
T
|
A
|
G
|
2
|
A
|
A
|
22
|
C
|
13
|
T
|
T
|
12
|
A
|
G
|
-
|
A
|
C
|
A
|
C
|
G
|
A
|
G
|
-
|
T
|
G
|
T
|
T
|
G
|
C
|
A
|
G
|
T
|
C
|
-
|
C
|
T
|
T
|
C
|
T
|
T
|
T
|
G
|
2
|
T
|
C
|
C
|
3
|
A
|
T
|
2
|
-
|
-
|
T
|
T
|
C
|
C
|
5
|
C
|
-
|
-
|
A
|
G
|
C
|
C
|
8
|
T
|
T
|
A
|
6
|
C
|
C
|
T
|
T
|
C
|
A
|
-
|
C
|
C
|
C
|
A
|
C
|
A
|
G
|
T
|
T
|
A
|
T
|
-
|
G
|
C
|
G
|
2
|
A
|
C
|
T
|
G
|
-
|
T
|
T
|
T
|
G
|
G
|
-
|
4/-
|
A
|
G
|
G
|
G
|
|