|
.997 |
.514 |
.468 |
.352 |
.329 |
.166 |
.028 |
.01 |
.001 |
.014 |
.016 |
.054 |
.248 |
.048 |
.002 |
.015 |
.0 |
.001 |
.009 |
.001 |
.016 |
.025 |
.001 |
.003 |
.0 |
.001 |
.0 |
.002 |
.05 |
.002 |
.001 |
.875 |
.01 |
.009 |
.001 |
.005 |
.078 |
.089 |
.09 |
.082 |
.0 |
-- |
.062 |
.192 |
.001 |
.003 |
.014 |
.016 |
.014 |
.343 |
.036 |
.017 |
.005 |
.0 |
.042 |
.003 |
.001 |
.0 |
.088 |
.003 |
.029 |
.039 |
.017 |
.418 |
.011 |
.009 |
.001 |
.0 |
.054 |
.054 |
.002 |
.082 |
.01 |
.026 |
.002 |
.005 |
.004 |
.01 |
.006 |
.002 |
.089 |
-- |
-- |
.001 |
.119 |
.0 |
.104 |
.005 |
.034 |
.03 |
.002 |
.249 |
.046 |
.001 |
.028 |
.001 |
.004 |
.116 |
.003 |
.127 |
-- |
.029 |
.005 |
.014 |
.001 |
.144 |
.003 |
.066 |
.002 |
.0 |
.001 |
.001 |
.181 |
.669 |
.0 |
.001 |
.001 |
.909 |
.032 |
.002 |
.009 |
.686 |
.922 |
.909 |
.001 |
.002 |
.0 |
.001 |
.006 |
.554 |
.003 |
.075 |
.618 |
.028 |
.211 |
.002 |
.053 |
.113 |
.0 |
.005 |
.166 |
.001 |
.393 |
.498 |
.581 |
.351 |
.538 |
.089 |
.002 |
-- |
-- |
-- |
.005 |
.235 |
.218 |
.937 |
.124 |
.003 |
.005 |
.001 |
.013 |
.006 |
.0 |
.998 |
.001 |
.002 |
.44 |
.719 |
.996 |
.005 |
.146 |
-- |
-- |
-- |
-- |
.003 |
.001 |
.008 |
.003 |
.121 |
.251 |
.004 |
.748 |
.002 |
.001 |
.001 |
.0 |
.0 |
.001 |
.036 |
.054 |
.054 |
.044 |
.001 |
.022 |
.124 |
.008 |
.001 |
.983 |
.035 |
.085 |
.044 |
.003 |
.027 |
.0 |
.0 |
.063 |
.002 |
.006 |
.001 |
.006 |
.033 |
.018 |
.001 |
.137 |
.019 |
.064 |
.202 |
.12 |
.328 |
.024 |
.018 |
.237 |
.355 |
.028 |
.004 |
.175 |
.0 |
.067 |
.0 |
.653 |
.049 |
.026 |
.005 |
.018 |
-- |
.772 |
.005 |
.017 |
.0 |
.003 |
.032 |
.0 |
.022 |
.002 |
.681 |
.005 |
.004 |
.021 |
.024 |
.044 |
.047 |
.001 |
.003 |
.999 |
.001 |
.863 |
.012 |
.036 |
.016 |
.0 |
.0 |
.001 |
.001 |
.001 |
.0 |
.008 |
.074 |
.003 |
.058 |
.001 |
.004 |
.0 |
.032 |
.079 |
-- |
.006 |
.003 |
.025 |
.088 |
.0 |
.023 |
.587 |
.065 |
.997 |
.002 |
.001 |
.009 |
.007 |
.0 |
.02 |
.136 |
.07 |
.077 |
.511 |
.034 |
.362 |
.362 |
.036 |
.005 |
.18 |
.001 |
.011 |
.038 |
.0 |
.034 |
.428 |
.848 |
|
Lgr4
|
Lgr4
|
Lgr4
|
Lgr4
|
Lgr4
|
Lgr4
|
Lgr4
|
Lgr4
|
Lgr4
|
Lgr4
|
Lgr4
|
Lgr4
|
Lgr4
|
Lgr4
|
Lgr4
|
Lgr4
|
Lgr4
|
Lgr4
|
Lgr4
|
Lgr4
|
Lgr4
|
Lgr4
|
Lgr4
|
Lgr4
|
Lgr4
|
Lgr4
|
Lgr4
|
Lgr4
|
Lgr4
|
Lgr4
|
Lgr4
|
|
--
|
--
|
--
|
--
|
--
|
--
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--
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--
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--
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--
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--
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|
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|
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|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
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|
--
|
--
|
--
|
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|
--
|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
--
|
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|
--
|
--
|
--
|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
--
|
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|
--
|
--
|
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|
--
|
--
|
--
|
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|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
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|
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|
--
|
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|
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|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
|
G |
T |
T |
G |
G |
G |
T |
T |
T |
T |
C |
A |
G |
C |
G |
2 |
C |
C |
G |
A |
T |
C |
C |
T |
T |
C |
C |
G |
T |
A |
A |
C |
3 |
T |
C |
2 |
2 |
C |
G |
2 |
C |
G |
G |
A |
T |
C |
4 |
G |
C |
G |
T |
T |
G |
C |
G |
C |
C |
G |
C |
T |
C |
C |
T |
G |
G |
C |
G |
C |
A |
T |
A |
G |
A |
G |
A |
C |
G |
T |
A |
G |
A |
A |
C |
4 |
T |
T |
C |
C |
A |
C |
G |
3 |
G |
G |
A |
G |
T |
C |
A |
A |
T |
A |
C |
G |
T |
3 |
A |
A |
G |
C |
C |
C |
G |
T |
T |
T |
T |
C |
T |
T |
T |
G |
2 |
T |
6 |
G |
T |
A |
C |
C |
C |
C |
A |
G |
G |
G |
A |
A |
T |
22 |
G |
A |
C |
4 |
10 |
G |
G |
C |
G |
G |
C |
C |
T |
T |
C |
G |
C |
C |
G |
A |
G |
C |
C |
C |
C |
C |
C |
G |
T |
C |
T |
C |
C |
A |
2 |
T |
C |
G |
C |
G |
T |
A |
T |
C |
9 |
G |
C |
C |
2 |
G |
T |
G |
A |
T |
T |
4 |
3 |
C |
T |
A |
8 |
C |
A |
G |
C |
A |
A |
G |
C |
A |
C |
T |
C |
A |
A |
T |
C |
12 |
G |
G |
G |
C |
A |
T |
A |
T |
G |
G |
14 |
T |
A |
T |
C |
A |
G |
G |
G |
T |
C |
C |
T |
G |
C |
G |
C |
T |
G |
A |
A |
3 |
C |
A |
T |
3 |
C |
G |
T |
T |
A |
T |
T |
C |
A |
C |
T |
C |
T |
G |
C |
A |
A |
T |
C |
C |
A |
A |
G |
T |
G |
T |
C |
A |
A |
A |
G |
A |
T |
C |
C |
C |
G |
G |
3 |
G |
9 |
C |
T |
T |
C |
T |
A |
G |
A |
A |
A |
A |
T |
A |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
A
|
C
|
C
|
GT/-
|
G/C
|
T
|
C
|
C
|
C
|
C
|
T
|
G
|
G/2
|
T
|
A
|
-
|
T
|
T
|
A
|
G
|
G
|
3
|
T
|
C
|
G
|
T
|
T
|
A
|
G
|
G
|
3
|
T
|
-
|
C
|
T
|
-
|
-
|
-
|
-
|
2/-
|
T
|
T
|
A
|
G
|
C
|
T
|
-
|
C
|
3
|
A
|
A
|
4
|
C
|
T
|
A
|
A
|
T
|
7
|
T
|
A
|
T
|
T
|
C
|
C
|
C
|
G
|
C
|
T
|
G
|
G
|
C
|
C
|
G
|
A
|
G
|
T
|
G/A
|
C
|
G
|
A
|
C
|
G
|
T
|
-
|
-
|
C
|
T
|
T
|
G
|
T
|
A
|
-
|
C
|
A
|
G
|
C
|
C
|
T
|
G
|
G
|
3
|
G
|
T
|
T
|
A
|
-
|
G
|
G
|
A
|
3
|
3/A
|
A
|
A
|
-
|
G
|
G
|
C
|
T
|
A
|
3
|
2
|
A
|
2/-
|
T/-
|
-
|
5
|
C
|
-
|
T
|
G
|
T
|
T
|
G
|
C
|
A
|
C
|
G
|
G
|
C
|
-
|
A
|
G
|
G
|
4/-
|
-
|
A
|
-
|
G
|
C
|
A
|
2
|
T
|
C
|
C
|
T
|
-
|
9
|
6
|
A
|
G
|
A
|
T
|
G
|
G
|
A
|
G
|
T
|
A
|
G
|
G
|
C
|
C/T
|
C/T
|
A/T
|
-
|
C
|
T
|
2
|
T
|
A
|
G
|
G
|
7
|
T
|
-
|
G/T
|
G
|
G
|
-
|
G/C
|
T/C
|
G/C
|
C
|
A
|
G
|
-
|
-
|
A
|
4
|
C
|
-
|
T
|
G
|
A
|
T
|
G
|
-
|
2
|
-
|
G
|
-
|
C
|
A
|
G
|
4
|
6
|
T
|
-
|
3
|
T
|
T
|
T
|
G
|
-
|
2
|
C
|
A
|
A
|
-
|
C
|
T
|
C
|
T
|
T
|
A
|
A
|
A
|
G
|
T
|
G
|
G
|
T
|
T
|
C
|
G
|
A
|
C
|
2
|
-
|
-
|
T
|
T
|
C
|
-
|
T
|
T
|
-
|
C
|
-
|
C
|
C
|
T
|
G
|
T
|
C
|
T
|
G
|
2
|
T
|
2
|
G
|
C
|
T
|
A
|
G
|
G
|
A
|
C
|
A
|
-
|
A
|
T
|
C
|
A/G
|
A
|
G
|
C
|
T
|
T
|
T
|
4
|
C
|
-
|
A
|
-
|
G
|
2
|
G
|
T
|
C
|
-
|
A
|
T
|
G
|
G
|
C
|
A
|
G
|
|