|
.536 |
.723 |
.313 |
.046 |
-- |
.379 |
.001 |
.001 |
.004 |
.0 |
.011 |
.011 |
.013 |
.001 |
.001 |
.023 |
.0 |
.125 |
.0 |
.0 |
.0 |
.003 |
.044 |
-- |
-- |
.197 |
.068 |
.0 |
.182 |
.445 |
.021 |
-- |
.0 |
1.0 |
.001 |
.0 |
.001 |
.001 |
.0 |
.01 |
.605 |
.014 |
-- |
.005 |
.0 |
.0 |
.0 |
.003 |
.79 |
.008 |
.028 |
.004 |
.729 |
.684 |
-- |
-- |
.073 |
.01 |
.003 |
.023 |
-- |
.13 |
.998 |
.0 |
.007 |
.015 |
.002 |
.0 |
.0 |
.087 |
.06 |
.012 |
.011 |
.048 |
.085 |
.008 |
.018 |
.0 |
.258 |
.013 |
.001 |
.091 |
.0 |
.032 |
.05 |
.013 |
.011 |
.004 |
.234 |
-- |
-- |
.002 |
.001 |
.103 |
.054 |
.073 |
.08 |
.018 |
.026 |
.0 |
.006 |
.001 |
.0 |
.006 |
.0 |
.001 |
.0 |
.0 |
.212 |
.003 |
.002 |
.0 |
.006 |
.017 |
.004 |
.004 |
.002 |
.038 |
.084 |
.022 |
.016 |
.005 |
.049 |
.001 |
.152 |
.001 |
.0 |
.0 |
.002 |
.003 |
.012 |
.076 |
.216 |
.064 |
.014 |
.011 |
.001 |
.0 |
.0 |
.026 |
.026 |
.03 |
.01 |
.07 |
.065 |
.071 |
.0 |
.002 |
.001 |
.044 |
.082 |
.043 |
.01 |
.013 |
.002 |
.005 |
.002 |
.007 |
.002 |
.001 |
.04 |
.017 |
.002 |
.031 |
.003 |
.006 |
.001 |
.006 |
.19 |
.008 |
.05 |
.003 |
.001 |
.003 |
.001 |
.001 |
.874 |
.001 |
.541 |
.002 |
.011 |
.003 |
.002 |
.01 |
.001 |
.0 |
.121 |
.0 |
.0 |
.078 |
.005 |
.0 |
.241 |
.001 |
.0 |
.0 |
.0 |
.001 |
.096 |
.01 |
.0 |
.008 |
.006 |
.003 |
-- |
.015 |
.001 |
.007 |
.934 |
.015 |
.0 |
.0 |
.002 |
.001 |
.0 |
.009 |
.96 |
.0 |
.0 |
.0 |
.016 |
.0 |
.006 |
.0 |
.0 |
.009 |
.014 |
-- |
-- |
-- |
-- |
.333 |
.01 |
.024 |
.002 |
.06 |
.492 |
.002 |
.026 |
.021 |
.003 |
.002 |
.003 |
.0 |
.003 |
.005 |
.0 |
.259 |
.005 |
.011 |
.294 |
.138 |
.05 |
.095 |
.01 |
.026 |
.085 |
.049 |
.007 |
.055 |
.044 |
.041 |
.003 |
.0 |
.004 |
.0 |
.012 |
.0 |
.045 |
.047 |
.036 |
.018 |
.039 |
.638 |
.195 |
.486 |
-- |
.002 |
.0 |
.001 |
.018 |
.039 |
.146 |
.069 |
.106 |
.005 |
.006 |
.0 |
.015 |
.035 |
.0 |
.042 |
.001 |
.005 |
.002 |
.0 |
.491 |
.0 |
.219 |
.003 |
.035 |
.018 |
.022 |
.012 |
.003 |
.032 |
|
Kcnd3
|
Kcnd3
|
Kcnd3
|
Kcnd3
|
Kcnd3
|
Kcnd3
|
Kcnd3
|
Kcnd3
|
Kcnd3
|
Kcnd3
|
Kcnd3
|
Kcnd3
|
Kcnd3
|
Kcnd3
|
Kcnd3
|
Kcnd3
|
Kcnd3
|
Kcnd3
|
Kcnd3
|
Kcnd3
|
Kcnd3
|
Kcnd3
|
Kcnd3
|
Kcnd3
|
Kcnd3
|
Kcnd3
|
Kcnd3
|
Kcnd3
|
Kcnd3
|
Kcnd3
|
Kcnd3
|
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
|
A |
G |
A |
A |
2 |
2 |
T |
G |
T |
C |
A |
G |
A |
G |
2 |
G |
G |
G |
80 |
A |
6 |
G |
T |
12 |
8 |
C |
T |
G |
4 |
8 |
G |
3 |
T |
T |
C |
T |
A |
A |
T |
C |
G |
5 |
8 |
2 |
C |
A |
G |
A |
C |
C |
A |
2 |
10 |
8 |
T |
T |
C |
T |
T |
20 |
G |
T |
A |
A |
T |
C |
C |
G |
C |
C |
A |
T |
C |
C |
G |
T |
C |
A |
10 |
C |
A |
A |
T |
C |
G |
T |
T |
G |
A |
G |
A |
G |
G |
G |
T |
8 |
6 |
C |
C |
G |
G |
A |
A |
T |
C |
A |
T |
A |
G |
G |
T |
T |
C |
3 |
T |
C |
2 |
4 |
G |
A |
A |
A |
A |
T |
60 |
G |
C |
C |
C |
C |
A |
G |
G |
G |
T |
A |
4 |
T |
T |
T |
T |
T |
T |
6 |
6 |
4 |
A |
8 |
10 |
32 |
11 |
A |
G |
G |
A |
G |
T |
G |
A |
A |
C |
C |
G |
C |
G |
A |
C |
A |
G |
C |
2 |
T |
A |
C |
T |
A |
A |
G |
C |
T |
C |
T |
C |
C |
C |
A |
C |
G |
3 |
G |
T |
A |
T |
A |
A |
T |
T |
G |
10 |
C |
A |
T |
C |
A |
C |
T |
C |
C |
G |
C |
C |
T |
G |
T |
T |
C |
T |
G |
A |
A |
G |
C |
A |
T |
T |
T |
A |
C |
T |
T |
C |
G |
C |
A |
A |
G |
A |
T |
C |
C |
T |
G |
G |
T |
14 |
A |
G |
A |
A |
G |
T |
T |
T |
G |
G |
G |
G |
4 |
G |
G |
4 |
A |
C |
A |
G |
G |
C |
G |
T |
G |
G |
A |
G |
G |
G |
T |
A |
A |
G |
A |
C |
A |
T |
T |
T |
T |
T |
T |
T |
A |
C |
A |
A |
A |
G |
A |
G |
C |
T |
A |
C |
C |
T |
A |
G |
A |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
G
|
A
|
G
|
G
|
-
|
-
|
C
|
A
|
-
|
A
|
G
|
A
|
G
|
23
|
-
|
A
|
A
|
A
|
-
|
T
|
6/-
|
T
|
2
|
-
|
-
|
-
|
C
|
A
|
-
|
8/-
|
A
|
-
|
C
|
2
|
T
|
C
|
G
|
G
|
C
|
G
|
3
|
-
|
-
|
-
|
T
|
C
|
A
|
G
|
T
|
20
|
G
|
-
|
-
|
8/-
|
C
|
C
|
T
|
C
|
3
|
-
|
G/A
|
A
|
G
|
G
|
T/3
|
G
|
T
|
4
|
T
|
T
|
G
|
C
|
2
|
2
|
A
|
G
|
G
|
G
|
10/-
|
5
|
3
|
A/2
|
G
|
T
|
?
|
C
|
C
|
T
|
5
|
A
|
2
|
A
|
21
|
T
|
C
|
8/-
|
6/-
|
T
|
T
|
10
|
C
|
G
|
T
|
C
|
A
|
G
|
A
|
G
|
A
|
C
|
2
|
7
|
-
|
-
|
19
|
G
|
-
|
-
|
A
|
G
|
4
|
G
|
G
|
G
|
-
|
A
|
G
|
T
|
T
|
T
|
C
|
A
|
C
|
A
|
G
|
5
|
-
|
G
|
A
|
G
|
A
|
A
|
G
|
6/-
|
6/-
|
4/-
|
2
|
8/-
|
10/-
|
-
|
-
|
T
|
G/21
|
2
|
G
|
T
|
G
|
A
|
-
|
G
|
T
|
A
|
A
|
T
|
A
|
G
|
T
|
-
|
A
|
T
|
-
|
A
|
G
|
T
|
2
|
G
|
-
|
17
|
T
|
C
|
T
|
2
|
T
|
T
|
T
|
7
|
T
|
A
|
-
|
A
|
C
|
G
|
2
|
G
|
G
|
C
|
C
|
T
|
-
|
T
|
C
|
-
|
6
|
52
|
4
|
C
|
T
|
T
|
A
|
G
|
T
|
A
|
A
|
C
|
C
|
G
|
G
|
T
|
G
|
C
|
A
|
T
|
2
|
G
|
C
|
4
|
2
|
A
|
C
|
C
|
T
|
3
|
A
|
G
|
G
|
A
|
-
|
C
|
2
|
2
|
C
|
-
|
T
|
G
|
-
|
C
|
A
|
G
|
G
|
11
|
-
|
C
|
C
|
C
|
A
|
A
|
C
|
-
|
9
|
A
|
-
|
T
|
T
|
G
|
G/-
|
A
|
T
|
A
|
C
|
A
|
A
|
G
|
T
|
A
|
A
|
3
|
19
|
G
|
A
|
2
|
T
|
G
|
12
|
A
|
C
|
G
|
C
|
C
|
C
|
G
|
10
|
G
|
-
|
G
|
2
|
3
|
A
|
T
|
A
|
G
|
T
|
3
|
C
|
G
|
T
|
G
|
|