|
.001 |
.001 |
.007 |
.001 |
.043 |
.006 |
.007 |
.015 |
-- |
.003 |
.002 |
.004 |
.006 |
.009 |
.545 |
.027 |
.002 |
.063 |
.089 |
.063 |
.041 |
.012 |
.012 |
.035 |
.003 |
.0 |
.001 |
.0 |
.002 |
.005 |
.012 |
.002 |
.032 |
.03 |
.07 |
.061 |
.627 |
.314 |
.474 |
.03 |
.968 |
.312 |
.02 |
.013 |
.021 |
.195 |
.769 |
.004 |
.047 |
.0 |
.971 |
.239 |
1.0 |
1.0 |
.978 |
.96 |
.957 |
.952 |
.099 |
.124 |
.0 |
.016 |
.001 |
.014 |
.109 |
.055 |
.059 |
-- |
.16 |
-- |
-- |
-- |
-- |
-- |
.0 |
.003 |
.089 |
.0 |
.029 |
.029 |
.096 |
.983 |
.986 |
.963 |
.895 |
.467 |
.002 |
.406 |
.276 |
.614 |
.006 |
.745 |
.643 |
.002 |
.008 |
.256 |
.002 |
.123 |
.001 |
.858 |
.004 |
.967 |
-- |
.007 |
.983 |
-- |
-- |
-- |
.063 |
-- |
.788 |
.009 |
.0 |
.0 |
.044 |
.387 |
.04 |
.0 |
-- |
-- |
-- |
-- |
.703 |
.001 |
.027 |
-- |
-- |
-- |
-- |
.065 |
.002 |
-- |
-- |
.051 |
.153 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
.161 |
.355 |
.076 |
.158 |
.029 |
-- |
-- |
-- |
.488 |
.052 |
.001 |
.114 |
.046 |
.048 |
.158 |
.005 |
.003 |
.007 |
.001 |
.011 |
.0 |
.019 |
.005 |
.018 |
.078 |
.064 |
.008 |
.041 |
.113 |
.001 |
.032 |
.0 |
.014 |
.005 |
.267 |
.018 |
.001 |
.008 |
.0 |
.004 |
.001 |
.005 |
.001 |
.001 |
.011 |
.008 |
.011 |
.019 |
.001 |
.0 |
.979 |
.008 |
.189 |
.04 |
.002 |
.0 |
.979 |
-- |
.037 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
.082 |
.001 |
.002 |
.004 |
.006 |
.018 |
.003 |
.001 |
.001 |
.02 |
.209 |
.085 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
.001 |
.006 |
.0 |
.006 |
.722 |
.633 |
.0 |
.01 |
-- |
-- |
.064 |
-- |
-- |
-- |
-- |
-- |
-- |
.002 |
.008 |
.236 |
.001 |
.004 |
.729 |
.005 |
-- |
.096 |
.003 |
.003 |
.008 |
.001 |
.006 |
.001 |
.12 |
.0 |
.091 |
.035 |
.021 |
-- |
-- |
-- |
.903 |
.948 |
.998 |
.993 |
.97 |
.963 |
.936 |
.889 |
.922 |
.993 |
.988 |
.986 |
.007 |
.006 |
.002 |
.0 |
-- |
.003 |
.003 |
.091 |
.014 |
.352 |
.0 |
.0 |
.011 |
.006 |
.001 |
.0 |
.005 |
.006 |
.021 |
.007 |
.001 |
.003 |
.017 |
.019 |
.038 |
.009 |
.473 |
.02 |
.111 |
.253 |
.238 |
.224 |
.21 |
.092 |
.055 |
.001 |
.061 |
.001 |
.015 |
.46 |
.007 |
.385 |
.003 |
-- |
.003 |
.001 |
-- |
.019 |
.927 |
.005 |
.023 |
.015 |
.02 |
.043 |
.998 |
.015 |
.006 |
.002 |
.184 |
.195 |
.575 |
.001 |
.246 |
.355 |
.001 |
.058 |
-- |
.0 |
-- |
-- |
-- |
.062 |
.0 |
.009 |
.122 |
.004 |
.021 |
.015 |
.003 |
.829 |
-- |
.961 |
.007 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
.001 |
.215 |
.002 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
.01 |
.001 |
.12 |
1.0 |
.149 |
.0 |
-- |
-- |
-- |
-- |
.005 |
.001 |
-- |
-- |
-- |
-- |
.0 |
.25 |
.016 |
.071 |
.006 |
.781 |
.002 |
.001 |
.022 |
.002 |
.053 |
.028 |
.062 |
.002 |
.003 |
.49 |
.548 |
.248 |
.189 |
.094 |
.841 |
.007 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
.002 |
.0 |
.0 |
.001 |
.001 |
.085 |
.003 |
.0 |
.003 |
.135 |
.74 |
.722 |
.042 |
-- |
-- |
-- |
.016 |
.009 |
.0 |
.003 |
.016 |
.09 |
.087 |
.271 |
.006 |
.001 |
.004 |
.085 |
.37 |
.272 |
.0 |
.001 |
.003 |
.0 |
.0 |
.009 |
.001 |
.011 |
.003 |
.154 |
.002 |
.0 |
.029 |
.001 |
.0 |
.003 |
.006 |
.068 |
.179 |
.01 |
.008 |
.066 |
.013 |
.002 |
.127 |
.0 |
.002 |
.014 |
.0 |
.022 |
-- |
.001 |
.437 |
-- |
.0 |
.0 |
.007 |
.041 |
.681 |
.102 |
.001 |
.015 |
-- |
-- |
-- |
-- |
.041 |
.0 |
.004 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
.114 |
.012 |
.035 |
.998 |
.016 |
.041 |
.998 |
.001 |
-- |
-- |
-- |
-- |
-- |
-- |
.013 |
.001 |
.001 |
.029 |
.034 |
.259 |
.007 |
.007 |
.0 |
.04 |
.001 |
.016 |
.074 |
.003 |
.671 |
.312 |
.0 |
.023 |
.002 |
.0 |
.181 |
.007 |
.029 |
.081 |
.034 |
-- |
-- |
-- |
.124 |
.009 |
.001 |
.003 |
.0 |
.0 |
.146 |
.831 |
.0 |
.051 |
.012 |
.002 |
.002 |
.092 |
.09 |
.002 |
.0 |
.373 |
.157 |
.053 |
.048 |
.001 |
.002 |
.013 |
.001 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
.0 |
.062 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
.007 |
.001 |
.023 |
.032 |
.0 |
.004 |
.005 |
.009 |
.013 |
.011 |
.066 |
.056 |
.003 |
.117 |
.086 |
.969 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
.055 |
.014 |
-- |
-- |
.16 |
.034 |
.013 |
.013 |
.015 |
.142 |
.006 |
.005 |
.006 |
.01 |
.004 |
.001 |
.0 |
.129 |
.002 |
.001 |
.001 |
.0 |
.003 |
.005 |
.193 |
.672 |
.456 |
.876 |
.304 |
.002 |
.001 |
.012 |
.094 |
.036 |
.074 |
.008 |
.014 |
.152 |
.147 |
.007 |
.02 |
.022 |
.047 |
.081 |
.099 |
.138 |
.015 |
.002 |
.026 |
.154 |
.097 |
.04 |
.103 |
.001 |
.089 |
.09 |
.937 |
.487 |
.023 |
.607 |
.138 |
.004 |
.006 |
.009 |
.064 |
.039 |
.053 |
.005 |
.261 |
.512 |
.161 |
.088 |
.001 |
.039 |
.003 |
.005 |
.011 |
.0 |
.001 |
.008 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
.004 |
-- |
.308 |
.019 |
.02 |
.001 |
.051 |
.241 |
.056 |
.001 |
.002 |
.019 |
.001 |
.0 |
.002 |
.151 |
.001 |
.0 |
.001 |
.001 |
.01 |
.012 |
.014 |
.006 |
.0 |
.014 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
.01 |
.021 |
.001 |
.0 |
.335 |
.0 |
.0 |
.167 |
-- |
-- |
-- |
.344 |
.23 |
.762 |
.109 |
.949 |
.011 |
.029 |
.019 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
.0 |
.002 |
.006 |
.003 |
.002 |
.015 |
.02 |
-- |
-- |
.009 |
.747 |
.001 |
-- |
.0 |
.01 |
.003 |
.003 |
.0 |
.001 |
-- |
-- |
-- |
.068 |
.066 |
.205 |
.955 |
.231 |
.008 |
.005 |
.002 |
.0 |
.024 |
.011 |
.011 |
.002 |
.003 |
.001 |
.0 |
.017 |
.0 |
.075 |
.0 |
.001 |
.211 |
.1 |
.748 |
.0 |
.002 |
.0 |
.001 |
.0 |
.014 |
.335 |
.176 |
.001 |
.068 |
.354 |
.355 |
.251 |
.017 |
-- |
.011 |
.782 |
.181 |
.038 |
.003 |
.0 |
.005 |
.002 |
.052 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
.095 |
.101 |
.766 |
.001 |
.027 |
-- |
.006 |
.02 |
.008 |
-- |
-- |
-- |
-- |
.039 |
.159 |
.14 |
.339 |
.345 |
.381 |
.002 |
.0 |
.0 |
.0 |
.06 |
.004 |
.017 |
.001 |
.009 |
.003 |
.0 |
.001 |
.052 |
.006 |
.512 |
.56 |
.0 |
.088 |
.001 |
.0 |
.085 |
.079 |
1.0 |
.002 |
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Kcnb2
|
Kcnb2
|
Kcnb2
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Kcnb2
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Kcnb2
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Kcnb2
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Kcnb2
|
Kcnb2
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Kcnb2
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Kcnb2
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Kcnb2
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Kcnb2
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Kcnb2
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Kcnb2
|
Kcnb2
|
Kcnb2
|
Kcnb2
|
Kcnb2
|
Kcnb2
|
Kcnb2
|
Kcnb2
|
Kcnb2
|
Kcnb2
|
Kcnb2
|
Kcnb2
|
Kcnb2
|
Kcnb2
|
Kcnb2
|
Kcnb2
|
Kcnb2
|
Kcnb2
|
Kcnb2
|
Kcnb2
|
Kcnb2
|
Kcnb2
|
Kcnb2
|
Kcnb2
|
Kcnb2
|
Kcnb2
|
Kcnb2
|
Kcnb2
|
Kcnb2
|
Kcnb2
|
Kcnb2
|
Kcnb2
|
Kcnb2
|
Kcnb2
|
Kcnb2
|
Kcnb2
|
Kcnb2
|
Kcnb2
|
Kcnb2
|
Kcnb2
|
Kcnb2
|
Kcnb2
|
Kcnb2
|
Kcnb2
|
Kcnb2
|
Kcnb2
|
Kcnb2
|
Kcnb2
|
Kcnb2
|
Kcnb2
|
Kcnb2
|
Kcnb2
|
Kcnb2
|
Kcnb2
|
Kcnb2
|
Kcnb2
|
Kcnb2
|
Kcnb2
|
Kcnb2
|
Kcnb2
|
Kcnb2
|
Kcnb2
|
Kcnb2
|
Kcnb2
|
Kcnb2
|
Kcnb2
|
Kcnb2
|
Kcnb2
|
Kcnb2
|
Kcnb2
|
Kcnb2
|
Kcnb2
|
Kcnb2
|
Kcnb2
|
Kcnb2
|
Kcnb2
|
Kcnb2
|
Kcnb2
|
Kcnb2
|
Kcnb2
|
Kcnb2
|
Kcnb2
|
Kcnb2
|
Kcnb2
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Kcnb2
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Kcnb2
|
Kcnb2
|
Kcnb2
|
Kcnb2
|
|
C |
C |
T |
3 |
A |
G |
T |
A |
C |
A |
C |
C |
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12 |
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2 |
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6 |
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11 |
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T
|
T
|
-
|
-
|
G
|
A
|
C
|
T
|
G
|
T
|
G
|
T
|
A
|
G
|
-
|
C
|
T
|
C
|
6/5
|
A
|
T
|
2/-
|
A/-
|
2
|
T
|
-
|
C
|
T
|
T
|
T
|
A
|
-
|
T
|
G
|
T
|
C
|
C
|
C
|
G
|
C
|
T
|
C
|
C
|
G
|
C
|
T
|
4
|
T
|
T
|
2
|
T
|
C
|
T
|
G
|
T
|
G
|
G
|
G
|
-
|
C
|
3/AT
|
A
|
-
|
2
|
9
|
-
|
G
|
A
|
2
|
A/G
|
A/G
|
A/G
|
G
|
G
|
T/G
|
C/G
|
T
|
5
|
A
|
C
|
A
|
A/T
|
A/T
|
A/T
|
C/T
|
A
|
-
|
-
|
C/2
|
T
|
2/-
|
A
|
-
|
A
|
C
|
G
|
A
|
C
|
A
|
T
|
5
|
2
|
G
|
T
|
T
|
-
|
-
|
A/T
|
T
|
11
|
-
|
A
|
C
|
T
|
C
|
A
|
C
|
-
|
C
|
C
|
C
|
T
|
T
|
4
|
9/7
|
G
|
A/C
|
A
|
A
|
G
|
5
|
A/G
|
G
|
C
|
G
|
T
|
C/3
|
13
|
T
|
T
|
T
|
3
|
G
|
G
|
C
|
A
|
3
|
C
|
C
|
C
|
C
|
G
|
C
|
G
|
C
|
C
|
T
|
-
|
C
|
T
|
A
|
-
|
C/A
|
T
|
T
|
C
|
T
|
G
|
G
|
C
|
G
|
T
|
G
|
G
|
A
|
A
|
T
|
C
|
G
|
G
|
-
|
5/T
|
A
|
G
|
C
|
-
|
T
|
T
|
C
|
T
|
T
|
G
|
A
|
T
|
2
|
A
|
2
|
-
|
A
|
G
|
G
|
G
|
G
|
A
|
C
|
C
|
A
|
A/G
|
A/G
|
A/G
|
T/A
|
G/A
|
G
|
C
|
3
|
C
|
G
|
T
|
A
|
T
|
A
|
A
|
G
|
-
|
G
|
T
|
C
|
T
|
C
|
C
|
-
|
C
|
T
|
-
|
2
|
C/A
|
C/A
|
C/A
|
C/A
|
C/A
|
C/A
|
C/A
|
A/C
|
A/C
|
A/C
|
A/C
|
A/C
|
A/C
|
C/A
|
T
|
G
|
T
|
G/C
|
G/C
|
2
|
5
|
T
|
T/C
|
-
|
G
|
T
|
A
|
C
|
C
|
A
|
C
|
T
|
G
|
A
|
8
|
C
|
A
|
C
|
-
|
C
|
C
|
T/G
|
C
|
A
|
G
|
A
|
T
|
C
|
C
|
T
|
G
|
T
|
-
|
T
|
G
|
T/C
|
T/4
|
C/2
|
-
|
3/-
|
C/2
|
3/-
|
G/4
|
C/T
|
C/T
|
G/A
|
G
|
-
|
C
|
-
|
C
|
2
|
G
|
C
|
C
|
T
|
G
|
T
|
C
|
-
|
-
|
G/A
|
G/A
|
G/A
|
G
|
3
|
7/-
|
A/-
|
T
|
4
|
-
|
T
|
T
|
-
|
T/C
|
T/C
|
T/C
|
T/C
|
G
|
C
|
C
|
T
|
A
|
T
|
C
|
C
|
-
|
A
|
3/CA
|
T/G
|
C
|
-
|
C/T
|
T
|
C
|
T
|
A
|
T
|
4
|
G
|
C
|
-
|
G
|
G/A
|
G/A
|
C
|
T
|
C
|
2
|
T
|
C
|
T
|
T
|
A/C
|
G/A
|
T/C
|
C
|
2
|
2
|
C
|
G
|
C
|
5/3
|
-
|
G
|
T
|
T
|
-
|
5
|
G
|
G
|
4/-
|
-
|
G
|
3/5
|
T
|
T
|
3
|
2
|
T
|
A
|
A
|
A
|
A
|
A
|
A
|
G
|
A
|
A
|
A
|
A
|
A
|
A
|
A
|
G
|
A
|
G
|
A
|
A
|
G
|
A
|
A
|
-
|
5
|
G/A
|
A
|
A
|
4
|
C
|
T
|
T
|
G
|
G/T
|
A/C
|
-
|
C/A
|
G/A
|
-
|
A/G
|
T/A
|
C/A
|
G
|
5
|
C
|
C
|
C
|
G
|
G
|
C
|
11
|
2
|
-
|
T/G
|
T
|
A
|
C
|
G/A
|
T/2
|
T
|
C
|
G
|
A
|
C
|
2
|
2
|
-
|
A
|
C/T
|
C
|
G
|
C
|
C
|
G
|
C
|
T
|
C
|
A
|
-
|
C
|
G
|
-
|
T
|
A
|
T
|
G
|
C
|
5
|
G
|
T
|
G
|
C
|
G
|
T
|
C
|
G
|
T
|
T
|
A
|
G
|
3
|
3
|
G
|
2
|
T
|
C
|
C
|
C
|
C
|
C
|
T
|
T
|
A
|
-
|
2
|
G
|
C
|
6
|
G
|
-
|
C/A
|
C/-
|
5/-
|
A
|
T
|
G
|
A
|
C
|
A
|
-
|
C
|
C
|
2
|
7
|
G
|
3/5
|
G
|
T
|
C
|
G
|
T/A
|
-
|
T
|
A
|
T/A
|
G/C
|
T/C
|
C
|
G
|
C
|
A
|
C
|
T/C
|
A
|
G
|
C
|
A
|
C
|
G/T
|
T/C
|
T/C
|
T/C
|
-
|
G
|
2
|
C
|
T
|
C
|
A
|
A/3
|
A/-
|
G
|
T/G
|
G/A
|
C/T
|
G
|
A
|
2
|
T
|
G
|
A/G
|
C
|
2
|
C
|
G
|
A
|
G
|
G
|
T
|
G
|
C/2
|
T
|
C/T
|
C/T
|
T/C
|
C/A
|
T
|
A
|
G
|
T
|
A
|
4/-
|
A/3
|
A
|
12
|
C
|
9
|
A
|
A
|
T
|
A
|
G
|
A
|
C
|
11
|
14
|
G
|
A
|
13
|
C/T
|
A
|
C/T
|
A/G
|
T
|
C
|
-
|
G
|
A
|
T
|
G
|
T
|
A
|
C
|
A
|
-
|
2
|
-
|
G
|
C
|
-
|
G
|
A
|
T
|
-
|
T/G
|
C
|
T
|
A
|
C/3
|
G
|
G
|
C/A
|
G/A
|
G/A
|
T
|
G
|
T
|
T/A
|
C/A
|
G/A
|
3/-
|
A/C
|
G
|
G
|
G
|
C/G
|
G/C
|
A/G
|
-
|
C
|
C
|
T
|
C/-
|
C/-
|
A/2
|
A/3
|
A
|
G
|
C
|
T
|
T
|
A
|
A
|
G
|
A
|
2
|
TC/-
|
A
|
A
|
T
|
T
|
T
|
G
|
T
|
G
|
A
|
G
|
2
|
T
|
2
|
A
|
A/3
|
3
|
C
|
C
|
A
|
G/T
|
G
|
T
|
G
|
A
|
C
|
2
|
T
|
C
|
A
|
-
|
G
|
T
|
-
|
A
|
C
|
T
|
A
|
C/G
|
G/C
|
G
|
T
|
T
|
T
|
T
|
C
|
T
|
C
|
C
|
A
|
T
|
G
|
G
|
G
|
T
|
A
|
14
|
-
|
G
|
C
|
-
|
-
|
-
|
-
|
-
|
T
|
A
|
G
|
G/2
|
A
|
C
|
T
|
T
|
T
|
G
|
A
|
T
|
2
|
3
|
3
|
C
|
11
|
G
|
-
|
A
|
A
|
A
|
T
|
2
|
-
|
T
|
A
|
G
|
A
|
C
|
T
|
A
|
C/G
|
6
|
7
|
A
|
C
|
C
|
T
|
A
|
C
|
2
|
G
|
T
|
A/C
|
C
|
G
|
C
|
-
|
-
|
C
|
C
|
G
|
2
|
T
|
G
|
C
|
A
|
3
|
T
|
T
|
C/A
|
T/G
|
A/G
|
T/G
|
G/T
|
A/G
|
6
|
T/A
|
A/T
|
C/G
|
C/T
|
C/G
|
G/A
|
C/T
|
C/A
|
A/G
|
C/T
|
A/T
|
G/A
|
A/G
|
G
|
A/C
|
G/C
|
C/T
|
A/T
|
C/T
|
C/G
|
C/T
|
G
|
-
|
A/-
|
-
|
3
|
2
|
C
|
G
|
T
|
2
|
A
|
A
|
A
|
A
|
T
|
C
|
T
|
G
|
A/G
|
-
|
5
|
A
|
G
|
-
|
G
|
A
|
T
|
T
|
A
|
G
|
C
|
C
|
G
|
T
|
A
|
A
|
C
|
G
|
A
|
3
|
A
|
-
|
-
|
G
|
T
|
G
|
C
|
4
|
A
|
G
|
T
|
T
|
T
|
G
|
-
|
G
|
A
|
G
|
G
|
G
|
G
|
A
|
A
|
A
|
2/-
|
A
|
-
|
4
|
A
|
C
|
C
|
T
|
G/3
|
G/T
|
T
|
A
|
C
|
T
|
-
|
A
|
C
|
G
|
G
|
C
|
C
|
T
|
C
|
C
|
C
|
T
|
C
|
T
|
3
|
C
|
T
|
G
|
-
|
2
|
-
|
C
|
T
|
C
|
C
|
T
|
G
|
G
|
T
|
-
|
-
|
-
|
G/A
|
G
|
C
|
T
|
T
|
A
|
A
|
T
|
C
|
A
|
C
|
C
|
C
|
T
|
C
|
C
|
G
|
2
|
G
|
C
|
G/C
|
G/A
|
G/A
|
G/A
|
-
|
C/G
|
C
|
T
|
C
|
-
|
-
|
3
|
C
|
G/A
|
C/T
|
3
|
-
|
-
|
C
|
G
|
G
|
G
|
G
|
A
|
14
|
G
|
C
|
-
|
G
|
G
|
G
|
G
|
G
|
C
|
T
|
C
|
T
|
2/-
|
-
|
T
|
A
|
-
|
T
|
A
|
G/-
|
A
|
C
|
|