|
.0 |
.004 |
.0 |
.0 |
.0 |
.004 |
.005 |
.001 |
.0 |
.08 |
.037 |
.009 |
.005 |
.006 |
.033 |
.025 |
.033 |
.227 |
.004 |
.0 |
.074 |
.008 |
.0 |
.01 |
.017 |
.004 |
.003 |
.029 |
.033 |
.002 |
.001 |
.73 |
.027 |
.014 |
.024 |
.611 |
.401 |
.017 |
.013 |
.207 |
.012 |
.174 |
.196 |
.031 |
.02 |
.031 |
.004 |
.02 |
.502 |
.001 |
.012 |
.011 |
-- |
-- |
-- |
-- |
.23 |
.003 |
.015 |
.018 |
.013 |
.019 |
.052 |
.046 |
.073 |
.281 |
.083 |
.158 |
.003 |
.001 |
.001 |
.008 |
.008 |
.008 |
.002 |
.001 |
.001 |
.001 |
.003 |
.0 |
.068 |
1.0 |
.998 |
.015 |
.027 |
.0 |
.002 |
.0 |
.0 |
.0 |
.017 |
.002 |
.0 |
.001 |
.005 |
.088 |
.042 |
.002 |
.019 |
.0 |
.005 |
.014 |
.108 |
.0 |
.002 |
.0 |
.011 |
.002 |
.002 |
.003 |
.001 |
.0 |
.0 |
.0 |
.01 |
.001 |
.001 |
.001 |
.037 |
.001 |
.002 |
.0 |
.382 |
.013 |
.0 |
.0 |
.005 |
.0 |
.0 |
.006 |
.005 |
.045 |
.001 |
.008 |
.002 |
.475 |
.022 |
.128 |
.141 |
.03 |
.002 |
.517 |
.011 |
.004 |
.003 |
.272 |
.039 |
-- |
.001 |
.001 |
.016 |
.006 |
.138 |
1.0 |
.011 |
.0 |
.013 |
.0 |
.001 |
.0 |
.016 |
.023 |
.002 |
.997 |
.105 |
.062 |
.026 |
.015 |
.0 |
.001 |
.001 |
.0 |
.002 |
.005 |
.005 |
.027 |
.002 |
.104 |
.521 |
.02 |
.007 |
|
Cyp4v3
|
Cyp4v3
|
Cyp4v3
|
Cyp4v3
|
Cyp4v3
|
Cyp4v3
|
Cyp4v3
|
Cyp4v3
|
Cyp4v3
|
Cyp4v3
|
Cyp4v3
|
Cyp4v3
|
Cyp4v3
|
Cyp4v3
|
Cyp4v3
|
Cyp4v3
|
Cyp4v3
|
Cyp4v3
|
Cyp4v3
|
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
|
G |
G |
T |
T |
T |
C |
G |
C |
G |
T |
A |
G |
T |
A |
G |
G |
T |
G |
C |
A |
G |
G |
T |
A |
T |
C |
C |
T |
C |
T |
A |
A |
A |
C |
G |
A |
T |
T |
T |
G |
C |
T |
G |
C |
G |
G |
T |
A |
T |
A |
C |
A |
A |
G |
T |
C |
T |
C |
A |
T |
A |
C |
A |
A |
A |
G |
C |
A |
5 |
T |
C |
G |
C |
T |
A |
G |
C |
A |
G |
C |
G |
T |
T |
A |
A |
G |
A |
A |
A |
T |
A |
T |
T |
A |
C |
G |
T |
A |
A |
A |
A |
C |
A |
T |
A |
T |
G |
C |
C |
A |
G |
C |
A |
A |
T |
T |
C |
T |
10 |
T |
T |
T |
C |
C |
A |
G |
T |
T |
C |
G |
T |
G |
A |
T |
C |
T |
G |
T |
2 |
A |
T |
2 |
A |
C |
C |
G |
C |
T |
T |
G |
C |
C |
T |
C |
C |
T |
A |
T |
T |
2 |
T |
G |
T |
T |
T |
T |
C |
A |
A |
A |
A |
A |
T |
C |
G |
T |
C |
T |
C |
C |
G |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
A
|
-
|
C
|
C
|
A
|
T
|
4/3
|
G
|
A
|
C
|
C
|
A
|
G
|
G
|
3
|
C
|
C
|
A
|
A
|
C
|
C
|
T
|
C
|
G
|
C
|
G
|
T
|
C
|
A
|
C
|
G
|
2
|
G
|
T
|
A
|
T
|
-
|
C
|
C
|
A
|
T
|
G
|
4
|
-
|
C
|
5
|
C
|
T
|
G
|
G
|
T
|
G
|
G
|
2
|
C
|
T
|
C
|
T
|
G
|
2
|
G
|
T
|
G
|
C
|
C
|
A
|
5
|
T
|
-
|
-
|
T
|
A
|
T
|
A
|
G
|
A
|
T
|
G
|
A
|
G
|
A
|
C
|
C
|
G
|
G
|
A
|
T
|
C
|
G
|
C
|
-
|
A
|
C
|
C
|
T
|
C
|
C
|
T
|
G
|
G
|
T
|
T
|
G
|
C
|
G
|
C
|
A
|
T
|
T
|
C
|
C
|
T
|
T
|
G
|
C
|
C
|
G
|
5
|
-
|
C
|
C
|
C
|
T
|
T
|
G
|
A
|
G
|
C
|
T
|
A
|
A
|
2
|
G
|
3
|
A
|
C
|
A
|
T/3
|
2/-
|
2
|
G
|
-
|
G
|
T
|
T
|
C
|
A
|
A
|
C
|
A
|
A
|
C/T
|
C
|
T
|
2
|
C
|
C
|
G
|
C
|
-
|
-
|
G/C
|
13
|
A
|
C
|
G
|
T
|
G
|
G
|
C
|
G
|
G
|
-
|
T
|
A
|
G
|
T
|
A
|
2
|
G
|
A
|
|