|
.045 |
.001 |
.11 |
-- |
-- |
-- |
-- |
.318 |
-- |
-- |
.027 |
.028 |
.139 |
.316 |
.323 |
.084 |
.004 |
-- |
-- |
-- |
.479 |
-- |
-- |
-- |
-- |
-- |
.081 |
.016 |
.015 |
.03 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
.072 |
.163 |
.263 |
.002 |
.004 |
.002 |
.048 |
.048 |
.002 |
.086 |
.102 |
.081 |
.035 |
-- |
-- |
-- |
-- |
-- |
.01 |
.002 |
.011 |
.002 |
.043 |
.072 |
.011 |
.105 |
.107 |
.108 |
.108 |
-- |
.048 |
.033 |
.087 |
-- |
.098 |
.127 |
.106 |
.006 |
.004 |
.02 |
-- |
-- |
.344 |
.16 |
.003 |
.201 |
-- |
.295 |
.007 |
.004 |
.033 |
.157 |
.034 |
.011 |
.033 |
.116 |
.114 |
.109 |
.141 |
.085 |
-- |
-- |
-- |
-- |
-- |
-- |
.006 |
.007 |
.083 |
.27 |
.187 |
.046 |
.317 |
.149 |
-- |
.259 |
.119 |
.045 |
.032 |
.053 |
.002 |
.004 |
.083 |
.018 |
.203 |
.687 |
-- |
-- |
-- |
-- |
-- |
.191 |
.561 |
.005 |
.001 |
.008 |
.0 |
.187 |
.001 |
.011 |
.004 |
.157 |
.002 |
.316 |
.3 |
.178 |
-- |
.899 |
.457 |
.019 |
.0 |
-- |
.015 |
-- |
-- |
.027 |
-- |
-- |
.061 |
.001 |
.044 |
.002 |
.221 |
.015 |
.029 |
-- |
-- |
-- |
.007 |
.001 |
.075 |
.123 |
-- |
-- |
-- |
-- |
.197 |
.346 |
.012 |
.261 |
.068 |
.023 |
-- |
-- |
-- |
-- |
.005 |
.32 |
.003 |
.018 |
-- |
-- |
-- |
.053 |
.015 |
-- |
.577 |
.006 |
.001 |
.004 |
.001 |
.004 |
.261 |
.024 |
.176 |
.0 |
.769 |
.003 |
.0 |
.31 |
.007 |
.059 |
.077 |
.298 |
.074 |
.027 |
.112 |
.251 |
.059 |
.0 |
.018 |
.003 |
.135 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
.703 |
.033 |
.035 |
-- |
-- |
.339 |
.02 |
.469 |
.087 |
.054 |
-- |
-- |
-- |
.002 |
.01 |
.26 |
.367 |
.509 |
.179 |
.0 |
.0 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
.004 |
.006 |
.011 |
.005 |
.794 |
-- |
-- |
.095 |
.179 |
.009 |
.013 |
.003 |
.009 |
.024 |
.0 |
.004 |
|
Cyp4f39
|
Cyp4f39
|
Cyp4f39
|
Cyp4f39
|
Cyp4f39
|
Cyp4f39
|
Cyp4f39
|
Cyp4f39
|
Cyp4f39
|
Cyp4f39
|
Cyp4f39
|
Cyp4f39
|
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|
Cyp4f39
|
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|
Cyp4f39
|
Cyp4f39
|
Cyp4f39
|
Cyp4f39
|
Cyp4f39
|
Cyp4f39
|
Cyp4f39
|
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|
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|
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|
Cyp4f39
|
Cyp4f39
|
Cyp4f39
|
Cyp4f39
|
Cyp4f39
|
Cyp4f39
|
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
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--
|
--
|
--
|
--
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--
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|
--
|
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|
--
|
--
|
--
|
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|
--
|
--
|
--
|
--
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--
|
--
|
--
|
--
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--
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--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
|
C |
50 |
G |
C |
A |
4 |
8 |
C |
18 |
16 |
A |
C |
7 |
T |
A |
T |
20 |
3 |
A |
G |
2 |
2 |
C |
T |
9 |
41 |
G |
G |
C |
T |
A |
T |
G |
C |
C |
A |
T |
A |
A |
C |
7 |
C |
A |
A |
C |
A |
T |
A |
A |
T |
A |
G |
G |
10 |
46 |
8 |
A |
G |
C |
10 |
A |
4 |
C |
G |
G |
C |
C |
A |
3 |
T |
T |
T |
T |
T |
T |
A |
A |
T |
T |
C |
A |
A |
C |
T |
T |
T |
T |
G |
4 |
2 |
G |
8 |
G |
T |
G |
G |
G |
A |
G |
4 |
T |
G |
A |
T |
T |
C |
T |
A |
T |
12 |
A |
C |
G |
A |
A |
T |
C |
C |
C |
G |
G |
T |
3 |
G |
C |
G |
C |
C |
G |
T |
A |
T |
A |
A |
C |
A |
A |
C |
G |
A |
T |
T |
T |
T |
C |
T |
C |
2 |
C |
A |
G |
C |
T |
A |
A |
3 |
A |
A |
T |
C |
A |
T |
T |
G |
G |
G |
G |
6 |
6 |
A |
G |
4 |
A |
C |
A |
A |
C |
T |
A |
2 |
G |
G |
G |
67 |
T |
2 |
C |
G |
T |
A |
2 |
12 |
T |
T |
T |
T |
T |
C |
C |
G |
C |
T |
C |
4 |
2 |
A |
T |
C |
34 |
C |
G |
C |
C |
G |
2 |
T |
G |
4 |
C |
G |
2 |
T |
C |
C |
2 |
G |
A |
4 |
4 |
G |
G |
C |
T |
C |
8 |
A |
A |
A |
G |
T |
C |
T |
9 |
G |
A |
G |
A |
15 |
C |
T |
C |
T |
2 |
C |
T |
A |
A |
16 |
14 |
G |
A |
T |
T |
C |
A |
A |
4 |
T |
T |
G |
T |
G |
C |
G |
T |
C |
C |
G |
12 |
G |
G |
T |
A |
T |
T |
3 |
2 |
G |
G |
12 |
C |
A |
3 |
A |
A |
A |
A |
G |
C |
C |
T |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
2
|
-
|
A
|
T
|
29
|
-
|
-
|
T
|
18/-
|
-
|
G
|
T
|
7/-
|
C
|
2
|
3/5
|
-
|
-
|
G
|
A
|
2/-
|
-
|
T
|
C
|
-
|
-
|
A
|
T
|
A
|
-
|
A/2
|
G
|
G/T
|
5
|
T
|
G
|
A
|
G
|
G
|
G
|
-
|
A
|
6
|
G
|
2
|
G
|
C
|
3
|
G
|
C
|
7
|
A
|
G/5
|
10/-
|
-
|
-
|
G
|
3
|
T
|
10/-
|
-
|
-
|
-
|
T
|
A
|
T
|
T
|
-
|
-
|
A
|
A
|
A
|
A
|
A
|
T/3
|
G
|
G
|
C
|
C
|
T
|
?
|
G
|
3
|
C
|
C
|
C
|
C
|
16
|
4/-
|
-
|
A
|
-
|
29/27
|
C
|
A
|
A
|
A
|
G
|
A
|
-
|
C
|
A
|
G
|
G
|
C
|
G
|
C
|
G
|
C
|
-
|
2
|
T
|
A
|
2
|
2
|
C
|
T
|
T
|
T
|
A
|
A
|
C
|
-
|
A
|
T
|
A
|
T
|
A
|
T
|
3/TA
|
G
|
C
|
3
|
G
|
T
|
G
|
C
|
T
|
A
|
G
|
C
|
C
|
G
|
T/99
|
T
|
40
|
13
|
2/-
|
2
|
G
|
C
|
T
|
C
|
2
|
G
|
-
|
G
|
G
|
C
|
2
|
G
|
5
|
G
|
A
|
C
|
A
|
A
|
-
|
6/-
|
A/15
|
A
|
-
|
2
|
T
|
A/-
|
T
|
T
|
T/C
|
G
|
-
|
2
|
A
|
A
|
67/-
|
A
|
-
|
-
|
A
|
C
|
A/G
|
-
|
-
|
-
|
A
|
C
|
C
|
T/5
|
T
|
C/T
|
3
|
3
|
7
|
3
|
-
|
-
|
G
|
C
|
T
|
-
|
G
|
2
|
T
|
A
|
A
|
-
|
C
|
A
|
-
|
G
|
C
|
-
|
C
|
T
|
T
|
-
|
G/A
|
G
|
4/-
|
-
|
G/9
|
A
|
T
|
11
|
T
|
-
|
G
|
G
|
G
|
-
|
C
|
2
|
A
|
-
|
A
|
G
|
10
|
G
|
-
|
T
|
C
|
A
|
T/2
|
2/-
|
9/7
|
C
|
C
|
G
|
16/-
|
14/-
|
T
|
G
|
C
|
C
|
T
|
G
|
A/5
|
4/-
|
C
|
G
|
A
|
C
|
2
|
T
|
A
|
C
|
8
|
T
|
2
|
12/-
|
T
|
A
|
C
|
G
|
A
|
C
|
-
|
2/-
|
A
|
A
|
-
|
T
|
A/G
|
-
|
G
|
G
|
C
|
7
|
C
|
G
|
T
|
C
|
|