|
.006 |
.002 |
.015 |
.005 |
.146 |
.003 |
.001 |
.005 |
.159 |
.088 |
.129 |
.031 |
.002 |
.815 |
.004 |
.297 |
.0 |
.007 |
.183 |
-- |
.024 |
.033 |
.084 |
.007 |
.089 |
.004 |
.012 |
.012 |
.29 |
.196 |
.001 |
.452 |
.002 |
.018 |
.028 |
.004 |
.0 |
.002 |
.001 |
.001 |
.003 |
.011 |
.001 |
.002 |
.002 |
.987 |
.007 |
.004 |
.002 |
.004 |
.004 |
.092 |
.006 |
-- |
.008 |
.009 |
.005 |
.02 |
.003 |
.003 |
.162 |
.004 |
.016 |
.937 |
.053 |
.036 |
.0 |
.338 |
.024 |
.0 |
.027 |
.002 |
.002 |
.007 |
.011 |
.009 |
.127 |
.001 |
.011 |
.004 |
.129 |
.003 |
.004 |
.018 |
.0 |
.007 |
.061 |
.001 |
.003 |
.0 |
.0 |
.0 |
.611 |
.842 |
.418 |
.005 |
.008 |
.749 |
.655 |
.349 |
.017 |
.006 |
.018 |
.002 |
.0 |
.005 |
.039 |
.043 |
.055 |
.0 |
.0 |
.027 |
.028 |
.002 |
.002 |
.002 |
.001 |
.007 |
.007 |
.001 |
.025 |
.049 |
.048 |
.006 |
.009 |
.001 |
.134 |
.186 |
.0 |
.001 |
.563 |
.006 |
.0 |
-- |
.0 |
.001 |
.012 |
.053 |
-- |
.012 |
.004 |
.002 |
.002 |
.0 |
.0 |
.017 |
.58 |
.083 |
.474 |
.005 |
.053 |
.004 |
.059 |
.0 |
.0 |
.0 |
.001 |
.086 |
.631 |
.001 |
.042 |
.077 |
.129 |
.038 |
.053 |
.009 |
.001 |
.001 |
.534 |
-- |
-- |
.037 |
.172 |
.036 |
.087 |
.0 |
.0 |
.0 |
.0 |
.0 |
.046 |
.006 |
.0 |
.075 |
.0 |
.001 |
.002 |
.012 |
.002 |
.003 |
.001 |
.001 |
.004 |
.0 |
.012 |
.005 |
.095 |
.0 |
.001 |
.13 |
.023 |
.876 |
.001 |
.0 |
.038 |
.315 |
.001 |
.009 |
.142 |
.162 |
.387 |
.01 |
.168 |
.198 |
.042 |
.091 |
.517 |
.921 |
.934 |
.907 |
.492 |
.514 |
.321 |
.005 |
.007 |
.045 |
.043 |
.015 |
.007 |
.029 |
.012 |
.01 |
.019 |
.004 |
.04 |
.04 |
.015 |
.02 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
.02 |
.241 |
.015 |
.352 |
.579 |
.09 |
.159 |
-- |
-- |
.024 |
.075 |
.298 |
.027 |
.02 |
.005 |
.017 |
.496 |
.108 |
.003 |
.003 |
.229 |
.005 |
.01 |
.02 |
.152 |
.087 |
.082 |
.072 |
.135 |
.008 |
.002 |
.038 |
.033 |
.012 |
.004 |
.005 |
.0 |
.921 |
.013 |
.015 |
-- |
.932 |
.005 |
.086 |
.016 |
.012 |
.007 |
.059 |
.014 |
.0 |
.269 |
.109 |
-- |
.011 |
.018 |
.347 |
.068 |
.147 |
.483 |
.147 |
.0 |
.0 |
.002 |
.0 |
.001 |
.0 |
.0 |
.001 |
.355 |
.357 |
.001 |
.001 |
.0 |
.256 |
.064 |
.021 |
.44 |
.001 |
.001 |
.319 |
.209 |
.028 |
.035 |
.026 |
.001 |
.001 |
.0 |
.059 |
.058 |
.005 |
.03 |
.006 |
.003 |
.013 |
.001 |
.002 |
.0 |
.001 |
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
|
Col6a6
|
Col6a6
|
Col6a6
|
Col6a6
|
Col6a6
|
Col6a6
|
Col6a6
|
Col6a6
|
Col6a6
|
Col6a6
|
Col6a6
|
Col6a6
|
Col6a6
|
Col6a6
|
Col6a6
|
Col6a6
|
Col6a6
|
Col6a6
|
Col6a6
|
Col6a6
|
Col6a6
|
Col6a6
|
Col6a6
|
Col6a6
|
Col6a6
|
Col6a6
|
Col6a6
|
Col6a6
|
Col6a6
|
Col6a6
|
Col6a6
|
Col6a6
|
Col6a6
|
Col6a6
|
Col6a6
|
|
G |
A |
G |
20 |
G |
T |
T |
T |
G |
2 |
T |
C |
C |
A |
C |
C |
C |
G |
C |
G |
A |
T |
2 |
A |
T |
T |
18 |
G |
C |
G |
A |
C |
T |
2 |
A |
4 |
C |
T |
A |
G |
T |
A |
4 |
G |
T |
G |
3 |
2 |
T |
A |
G |
A |
C |
C |
C |
A |
4 |
C |
G |
A |
A |
T |
G |
G |
G |
G |
C |
C |
3 |
C |
G |
A |
T |
A |
T |
A |
G |
A |
T |
A |
C |
G |
A |
T |
C |
G |
C |
G |
C |
T |
A |
G |
C |
T |
C |
T |
C |
T |
A |
G |
G |
2 |
T |
C |
T |
A |
A |
T |
T |
A |
A |
G |
C |
12 |
10 |
8 |
C |
T |
T |
A |
3 |
G |
G |
G |
A |
A |
A |
A |
A |
G |
C |
T |
G |
T |
T |
6 |
G |
G |
T |
A |
C |
A |
G |
T |
A |
8 |
A |
T |
G |
T |
3 |
G |
C |
A |
A |
G |
T |
T |
A |
C |
A |
G |
T |
9 |
C |
C |
C |
A |
T |
G |
A |
G |
C |
C |
C |
T |
C |
T |
C |
A |
T |
T |
T |
A |
T |
C |
G |
T |
A |
C |
G |
A |
C |
C |
2 |
A |
A |
G |
C |
G |
T |
G |
G |
A |
T |
C |
A |
G |
T |
G |
G |
G |
C |
T |
T |
A |
T |
T |
A |
G |
T |
T |
A |
A |
A |
G |
C |
G |
G |
G |
T |
A |
G |
C |
C |
A |
C |
C |
A |
A |
C |
C |
C |
A |
G |
G |
C |
2 |
A |
G |
G |
G |
A |
G |
6 |
G |
T |
2 |
104 |
T |
G |
C |
G |
C |
C |
10 |
C |
A |
G |
A |
G |
A |
G |
A |
T |
A |
C |
G |
G |
T |
G |
A |
T |
C |
C |
A |
C |
C |
A |
C |
C |
T |
C |
A |
T |
T |
G |
G |
C |
C |
A |
24 |
G |
C |
T |
G |
G |
A |
4 |
A |
C |
A |
C |
A |
A |
G |
A |
A |
2 |
A |
G |
A |
A |
A |
A |
G |
T |
G |
T |
A |
T |
C |
G |
G |
G |
T |
C |
10 |
8 |
T |
9 |
C |
T |
T |
G |
2 |
C |
C |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
A
|
G
|
A
|
-
|
A
|
C
|
C
|
C
|
A
|
-
|
C
|
T
|
13
|
C
|
T
|
G
|
A
|
A
|
T
|
5
|
C
|
C
|
-
|
G
|
C
|
C
|
-
|
-
|
4
|
T
|
G
|
T
|
A
|
-
|
G
|
-
|
A
|
C
|
AT/3
|
A
|
A
|
T
|
-
|
A
|
C
|
T
|
3/-
|
2/-
|
T/-
|
2
|
A
|
A/-
|
T
|
A
|
G
|
G
|
-
|
T
|
23
|
G
|
11
|
A
|
A
|
C
|
2
|
C
|
A
|
T
|
-
|
T
|
A
|
G
|
G
|
G
|
C
|
G
|
A
|
T
|
G
|
C
|
A
|
T
|
-
|
G
|
T
|
A
|
T
|
A
|
T
|
2
|
G
|
A
|
G
|
C
|
T
|
C
|
T
|
A
|
G
|
A
|
C
|
-
|
C
|
G
|
C
|
G
|
G
|
3
|
2
|
T
|
G
|
-
|
A
|
12/-
|
10/-
|
8/-
|
T
|
C
|
C
|
G
|
-
|
2
|
A
|
2
|
T
|
G
|
2
|
12
|
-
|
A
|
T
|
C
|
T
|
4
|
C
|
-
|
G/2
|
C
|
T/2
|
G
|
T
|
T
|
A
|
C
|
G
|
-
|
6
|
C
|
A
|
C
|
-
|
A
|
T
|
G
|
T
|
T
|
A
|
-
|
T
|
G
|
T
|
A
|
C
|
-
|
A
|
G
|
T
|
G
|
C
|
A
|
G
|
A
|
A
|
T
|
9
|
G
|
T
|
C
|
G
|
G
|
C
|
C
|
C
|
G
|
C
|
T
|
2
|
G
|
T
|
T
|
A
|
-
|
T
|
T
|
-
|
G
|
G
|
A
|
3
|
A
|
C
|
3
|
A
|
G
|
C
|
T
|
G
|
3/9
|
-
|
A
|
A
|
T
|
-
|
C
|
3
|
G
|
C
|
3
|
G
|
A
|
C
|
C
|
G
|
T
|
G
|
A
|
G
|
T
|
A
|
A
|
C
|
G
|
A
|
T
|
2
|
G
|
A
|
2
|
C
|
G
|
G
|
A
|
-
|
-
|
A
|
A
|
T
|
-
|
G
|
A
|
T
|
A
|
G
|
G/2
|
6/-
|
T
|
A
|
-
|
-
|
G
|
A
|
T
|
A
|
5
|
T
|
10/12
|
T
|
T
|
T
|
A/41
|
G/25
|
G
|
C
|
-
|
6
|
2
|
A
|
3
|
A
|
C
|
T
|
G
|
2
|
A
|
T
|
2
|
T
|
T
|
12
|
A
|
5
|
C
|
T
|
2
|
C
|
A
|
A
|
15
|
T
|
T
|
G
|
24/-
|
G/3
|
T
|
C
|
A
|
A
|
2
|
-
|
6
|
T
|
C
|
T
|
C
|
C
|
A
|
G
|
C
|
2/-
|
A/-
|
A
|
G
|
G
|
2
|
-
|
A
|
G
|
A
|
C
|
2
|
13
|
T
|
A
|
A
|
A
|
75
|
T
|
10/-
|
-
|
3
|
-
|
T
|
20
|
5
|
23
|
-
|
G
|
T
|
|