|
.001 |
.009 |
.017 |
-- |
.029 |
.079 |
.009 |
-- |
.001 |
.001 |
.019 |
-- |
.039 |
.066 |
.01 |
.007 |
.037 |
.205 |
.2 |
-- |
-- |
.078 |
.01 |
.019 |
-- |
.001 |
.002 |
.004 |
.762 |
.002 |
.005 |
-- |
-- |
-- |
.017 |
.017 |
.383 |
.173 |
.017 |
.015 |
.239 |
.64 |
.253 |
.002 |
.001 |
.004 |
.003 |
.0 |
.913 |
.519 |
.067 |
.058 |
.014 |
.045 |
.024 |
.001 |
.006 |
.012 |
.033 |
.016 |
.02 |
-- |
-- |
.016 |
.037 |
.006 |
.007 |
.003 |
.002 |
.15 |
.0 |
.0 |
.0 |
.0 |
.001 |
.093 |
.009 |
.013 |
.003 |
.002 |
.002 |
.003 |
.007 |
.019 |
.002 |
.0 |
.002 |
.002 |
.003 |
.001 |
.014 |
.005 |
.002 |
.0 |
.0 |
.0 |
.0 |
.001 |
.002 |
.001 |
.001 |
.001 |
.832 |
.118 |
.009 |
.119 |
.186 |
.191 |
.018 |
.021 |
.0 |
.012 |
.002 |
.05 |
.095 |
.101 |
.164 |
-- |
.0 |
.051 |
.001 |
.004 |
.0 |
.227 |
.448 |
.423 |
.001 |
.001 |
.004 |
.0 |
.254 |
.0 |
.0 |
.038 |
.016 |
.0 |
.082 |
.003 |
.0 |
.0 |
.003 |
.001 |
.005 |
.0 |
.0 |
.002 |
.001 |
.001 |
.004 |
.001 |
.0 |
.001 |
.001 |
.003 |
.055 |
.508 |
.045 |
.023 |
.169 |
.227 |
.201 |
.195 |
.195 |
.114 |
.079 |
.28 |
.058 |
.004 |
.007 |
.037 |
.019 |
.102 |
.0 |
.0 |
.0 |
.012 |
-- |
.003 |
.044 |
.0 |
.009 |
.054 |
.007 |
.052 |
.001 |
.012 |
.002 |
.0 |
.487 |
.001 |
.002 |
.72 |
.004 |
.013 |
.0 |
.001 |
.005 |
.005 |
.0 |
.002 |
.002 |
.06 |
.409 |
.0 |
.001 |
.0 |
.694 |
.008 |
.0 |
.001 |
.001 |
.014 |
.001 |
.003 |
.005 |
.006 |
.019 |
.009 |
.051 |
.002 |
.003 |
.001 |
.008 |
.003 |
.005 |
.002 |
.009 |
.032 |
.069 |
.0 |
.378 |
.001 |
.009 |
.101 |
.0 |
.003 |
.001 |
.995 |
.004 |
.013 |
.072 |
.006 |
.002 |
.007 |
.005 |
.0 |
.0 |
.07 |
.115 |
.028 |
.016 |
.024 |
.001 |
.001 |
.0 |
.002 |
.0 |
.001 |
.025 |
.0 |
.689 |
.001 |
.001 |
.0 |
.02 |
.005 |
.001 |
.0 |
.01 |
.001 |
.0 |
.009 |
.011 |
.006 |
.0 |
.0 |
.0 |
.0 |
.773 |
.001 |
.005 |
.034 |
.0 |
.003 |
.002 |
.002 |
.003 |
.004 |
.001 |
.021 |
.001 |
.0 |
.0 |
.019 |
.0 |
.001 |
.016 |
.076 |
.056 |
.003 |
.003 |
.268 |
.142 |
-- |
-- |
.03 |
.003 |
.0 |
.005 |
.0 |
.0 |
.038 |
.001 |
.811 |
|
Col5a1
|
Col5a1
|
Col5a1
|
Col5a1
|
Col5a1
|
Col5a1
|
Col5a1
|
Col5a1
|
Col5a1
|
Col5a1
|
Col5a1
|
Col5a1
|
Col5a1
|
Col5a1
|
Col5a1
|
Col5a1
|
Col5a1
|
Col5a1
|
Col5a1
|
Col5a1
|
Col5a1
|
Col5a1
|
Col5a1
|
Col5a1
|
Col5a1
|
Col5a1
|
Col5a1
|
Col5a1
|
Col5a1
|
Col5a1
|
Col5a1
|
Col5a1
|
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
|
A |
A |
G |
2 |
2 |
G |
A |
A |
T |
C |
C |
2 |
A |
16 |
T |
T |
G |
C |
G |
T |
A |
T |
C |
C |
C |
C |
C |
T |
T |
T |
C |
G |
2 |
8 |
C |
G |
T |
T |
T |
A |
T |
A |
T |
T |
T |
A |
G |
A |
20 |
4 |
4 |
T |
G |
A |
A |
C |
T |
G |
G |
A |
A |
G |
A |
6 |
3 |
C |
A |
A |
T |
G |
A |
T |
A |
T |
G |
A |
T |
A |
A |
A |
C |
A |
C |
G |
A |
C |
A |
G |
G |
G |
G |
T |
C |
G |
T |
G |
G |
C |
A |
G |
C |
T |
C |
C |
T |
6 |
4 |
G |
G |
T |
C |
C |
G |
A |
G |
T |
T |
G |
C |
T |
T |
T |
T |
C |
C |
G |
C |
T |
C |
C |
C |
C |
6 |
C |
3 |
G |
C |
C |
C |
C |
A |
A |
C |
C |
C |
C |
C |
C |
T |
A |
A |
C |
A |
G |
T |
T |
G |
A |
A |
A |
G |
C |
A |
2 |
A |
T |
5 |
A |
4 |
2 |
G |
T |
C |
T |
G |
A |
2 |
G |
5 |
A |
C |
T |
G |
C |
A |
4 |
A |
T |
2 |
C |
4 |
T |
T |
G |
A |
G |
A |
A |
A |
A |
16 |
T |
G |
4 |
G |
T |
T |
2 |
A |
G |
G |
C |
G |
T |
4 |
G |
G |
C |
C |
T |
A |
G |
C |
C |
C |
T |
G |
T |
G |
G |
C |
A |
G |
G |
A |
C |
T |
C |
A |
C |
G |
T |
C |
T |
C |
T |
A |
T |
T |
14 |
C |
3 |
T |
A |
A |
G |
G |
T |
G |
6 |
T |
T |
C |
G |
C |
2 |
T |
T |
18 |
G |
G |
T |
G |
C |
T |
A |
T |
A |
C |
G |
C |
C |
G |
A |
A |
G |
T |
A |
A |
C |
C |
A |
G |
G |
2 |
G |
C |
C |
T |
T |
C |
C |
A |
T |
C |
A |
A |
T |
G |
C |
T |
C |
A |
T |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
3
|
3
|
A
|
-
|
2/-
|
T
|
G
|
173
|
5
|
A
|
3
|
-
|
G
|
16/-
|
5
|
C
|
A
|
17
|
T
|
9
|
G
|
C
|
T
|
T
|
-
|
T
|
T
|
C
|
C
|
C
|
G
|
T
|
2/-
|
8/-
|
A
|
-
|
19
|
C
|
G
|
G
|
2
|
5
|
C
|
G
|
C
|
G
|
3
|
5
|
-
|
4/-
|
-
|
A
|
33
|
49
|
9
|
T
|
C
|
A
|
A
|
-
|
G
|
A
|
11
|
6/-
|
3/-
|
T
|
G
|
T
|
C
|
A
|
T
|
A
|
G
|
C
|
60
|
G
|
C
|
G
|
C
|
C
|
T
|
G
|
G
|
A
|
G
|
G
|
G
|
A
|
C
|
T
|
A
|
G
|
T
|
A
|
C
|
A
|
4
|
T
|
G
|
A
|
G
|
C
|
T
|
C/2
|
G
|
6/-
|
4/-
|
10
|
A
|
11
|
T
|
T
|
T
|
G
|
A
|
C
|
C
|
A
|
G
|
C
|
C
|
-
|
A
|
8
|
T
|
A
|
T
|
C
|
T
|
G
|
G
|
T
|
-
|
T
|
-
|
A
|
T
|
T
|
3
|
T
|
G
|
T
|
T
|
T
|
G
|
T
|
G
|
T
|
3/TG
|
G
|
G
|
T
|
G
|
13
|
-
|
A
|
-
|
T
|
11
|
C
|
A
|
G
|
G
|
-
|
G
|
C
|
-
|
G
|
-
|
-
|
A
|
C
|
T
|
C
|
A
|
G
|
-
|
A
|
-
|
G
|
T
|
C
|
A
|
T
|
G
|
-
|
9
|
C
|
2/-
|
-
|
-
|
C
|
C
|
A
|
G
|
A
|
2
|
19
|
G
|
C
|
-
|
G
|
A
|
-
|
A
|
G
|
39
|
-
|
G
|
A
|
T
|
T
|
A
|
C
|
-
|
A
|
A
|
T
|
5
|
A
|
G
|
A
|
T
|
G
|
T
|
C
|
A
|
A
|
T
|
A
|
T
|
G
|
A
|
A
|
G
|
T
|
C
|
T
|
-
|
A
|
A
|
C
|
T
|
G
|
T
|
C
|
G
|
C
|
11
|
14/-
|
-
|
-
|
C
|
G
|
G
|
A
|
C
|
3
|
A
|
-
|
C
|
C
|
T
|
C
|
T
|
-
|
C
|
C
|
-
|
3
|
A
|
C
|
T
|
T
|
C
|
T
|
C
|
G
|
T
|
G/-
|
-
|
C/T
|
A
|
G
|
G
|
A
|
C
|
G
|
G
|
T
|
T
|
G
|
C
|
2
|
-
|
C
|
A
|
T
|
C
|
C
|
T
|
-
|
2
|
T/9
|
T
|
G
|
G
|
C
|
A
|
T
|
C
|
T
|
G
|
C
|
|