|
.058 |
.566 |
.212 |
.021 |
.019 |
.012 |
.748 |
.022 |
-- |
.02 |
.003 |
.001 |
.995 |
.007 |
.024 |
.0 |
.003 |
.001 |
.001 |
.068 |
.004 |
.003 |
.093 |
.636 |
.0 |
.084 |
.072 |
-- |
-- |
-- |
-- |
.97 |
.97 |
.242 |
.049 |
.065 |
.271 |
.007 |
.001 |
.001 |
.011 |
.028 |
.005 |
.006 |
.008 |
.018 |
.784 |
.004 |
.102 |
.001 |
.001 |
.029 |
.051 |
.078 |
.0 |
.001 |
.394 |
.006 |
.0 |
.1 |
.109 |
.162 |
.135 |
.467 |
.356 |
.001 |
.814 |
.31 |
.046 |
.062 |
.026 |
.052 |
.053 |
.056 |
.003 |
.001 |
.034 |
.521 |
.002 |
.004 |
.009 |
.021 |
.001 |
.034 |
.0 |
.066 |
.005 |
.003 |
.001 |
.031 |
.065 |
.031 |
.112 |
.065 |
.299 |
.861 |
.14 |
.659 |
.0 |
.0 |
.009 |
.007 |
.0 |
.001 |
.001 |
.001 |
.009 |
.001 |
.131 |
.141 |
.006 |
.015 |
.001 |
.001 |
-- |
-- |
.879 |
.001 |
.009 |
.0 |
.015 |
.002 |
.003 |
.017 |
.093 |
.026 |
-- |
-- |
.044 |
.018 |
.003 |
.166 |
.065 |
.007 |
.1 |
.619 |
.001 |
.014 |
.001 |
.0 |
.002 |
.0 |
.008 |
.0 |
.007 |
.005 |
.003 |
-- |
-- |
.263 |
.84 |
.101 |
.017 |
.003 |
.001 |
.007 |
.609 |
.016 |
.018 |
.021 |
.13 |
.002 |
.002 |
.185 |
.335 |
.001 |
.005 |
.005 |
.044 |
.0 |
.003 |
.032 |
.001 |
.0 |
.0 |
.002 |
.172 |
.012 |
.075 |
.411 |
.062 |
.115 |
.387 |
.421 |
.455 |
.541 |
.608 |
.0 |
.042 |
.005 |
.202 |
.002 |
.002 |
.001 |
.724 |
.297 |
.799 |
.735 |
.676 |
.694 |
.086 |
.003 |
.013 |
.002 |
.004 |
.989 |
.003 |
.0 |
.026 |
.0 |
.001 |
.982 |
.071 |
.026 |
.011 |
.012 |
.069 |
.08 |
.044 |
-- |
.102 |
.001 |
.0 |
.043 |
.014 |
.079 |
.006 |
.0 |
.997 |
.0 |
.001 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
.004 |
.0 |
.003 |
.001 |
.001 |
.0 |
.001 |
.001 |
.001 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
.029 |
.177 |
.032 |
-- |
-- |
-- |
-- |
-- |
.109 |
.054 |
.029 |
.014 |
.001 |
.04 |
.001 |
.22 |
.216 |
-- |
.134 |
.002 |
.002 |
.001 |
-- |
-- |
.001 |
.189 |
.379 |
.073 |
-- |
.002 |
-- |
.001 |
.001 |
.0 |
.068 |
.003 |
.003 |
.002 |
.0 |
.0 |
.001 |
.007 |
.581 |
.0 |
.957 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
.007 |
.168 |
.054 |
.018 |
.009 |
.009 |
.008 |
-- |
-- |
.01 |
.0 |
.017 |
.013 |
.001 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
.003 |
.467 |
.321 |
.002 |
.007 |
.004 |
.164 |
.085 |
.005 |
.001 |
.005 |
.007 |
.003 |
.105 |
.039 |
.221 |
.023 |
-- |
-- |
-- |
.011 |
.001 |
.0 |
.001 |
.118 |
.067 |
.003 |
.233 |
.004 |
.097 |
.0 |
.007 |
.063 |
.004 |
.022 |
.015 |
.084 |
.009 |
.588 |
.003 |
.128 |
.179 |
.0 |
.049 |
.0 |
.0 |
.0 |
.005 |
.002 |
.104 |
.289 |
.04 |
.095 |
.095 |
.097 |
.027 |
-- |
-- |
-- |
-- |
-- |
.022 |
.329 |
.007 |
.001 |
.007 |
.002 |
.05 |
.25 |
.065 |
.046 |
.024 |
-- |
-- |
-- |
.017 |
.054 |
.001 |
.001 |
.015 |
.002 |
.003 |
.001 |
.35 |
.742 |
.001 |
.019 |
.244 |
.008 |
.008 |
.001 |
.032 |
.054 |
.004 |
.068 |
.063 |
.493 |
-- |
-- |
.023 |
.065 |
.019 |
.034 |
.055 |
.003 |
.062 |
.052 |
.001 |
.0 |
.001 |
.0 |
.33 |
.062 |
.063 |
.0 |
.0 |
.001 |
.045 |
.164 |
.001 |
.131 |
.004 |
.004 |
.001 |
.004 |
.005 |
.005 |
.14 |
.013 |
.015 |
.068 |
.001 |
.029 |
.593 |
.071 |
.008 |
.067 |
.003 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
.002 |
.026 |
.062 |
.009 |
.01 |
.044 |
.081 |
.001 |
.0 |
.999 |
.001 |
.013 |
.305 |
.004 |
.001 |
.008 |
.001 |
.003 |
.072 |
.001 |
.001 |
.016 |
.088 |
.073 |
.011 |
.0 |
.0 |
.001 |
.001 |
.128 |
.008 |
.004 |
.004 |
.001 |
-- |
.077 |
.417 |
.252 |
.508 |
.072 |
.0 |
.001 |
.0 |
.011 |
.315 |
.639 |
|
Cdc14a
|
Cdc14a
|
Cdc14a
|
Cdc14a
|
Cdc14a
|
Cdc14a
|
Cdc14a
|
Cdc14a
|
Cdc14a
|
Cdc14a
|
Cdc14a
|
Cdc14a
|
Cdc14a
|
Cdc14a
|
Cdc14a
|
Cdc14a
|
Cdc14a
|
Cdc14a
|
Cdc14a
|
Cdc14a
|
Cdc14a
|
Cdc14a
|
Cdc14a
|
Cdc14a
|
Cdc14a
|
Cdc14a
|
Cdc14a
|
Cdc14a
|
Cdc14a
|
Cdc14a
|
Cdc14a
|
Cdc14a
|
Cdc14a
|
Cdc14a
|
Cdc14a
|
Cdc14a
|
Cdc14a
|
Cdc14a
|
Cdc14a
|
Cdc14a
|
Cdc14a
|
Cdc14a
|
Cdc14a
|
Cdc14a
|
Cdc14a
|
Cdc14a
|
Cdc14a
|
Cdc14a
|
Cdc14a
|
Cdc14a
|
Cdc14a
|
Cdc14a
|
Cdc14a
|
Cdc14a
|
Cdc14a
|
Cdc14a
|
Cdc14a
|
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
|
A |
G |
G |
T |
12 |
8 |
A |
A |
T |
A |
3 |
C |
G |
C |
T |
A |
4 |
C |
A |
T |
C |
A |
G |
C |
T |
C |
C |
G |
T |
8 |
T |
10 |
8 |
3 |
G |
A |
G |
G |
2 |
C |
C |
T |
T |
2 |
T |
T |
2 |
C |
G |
A |
G |
A |
2 |
T |
G |
3 |
A |
T |
T |
A |
A |
2 |
G |
G |
T |
G |
T |
T |
A |
T |
G |
C |
T |
T |
3 |
G |
A |
T |
T |
C |
4 |
A |
G |
T |
G |
G |
T |
T |
G |
C |
A |
G |
T |
G |
T |
C |
A |
C |
A |
G |
C |
G |
A |
A |
T |
C |
G |
G |
4 |
2 |
T |
A |
C |
C |
C |
G |
G |
G |
T |
A |
A |
C |
T |
G |
T |
A |
A |
C |
A |
C |
T |
G |
8 |
G |
C |
C |
T |
A |
C |
A |
G |
T |
C |
A |
G |
T |
C |
5 |
2 |
C |
G |
T |
T |
C |
A |
T |
T |
C |
A |
G |
G |
C |
T |
A |
A |
T |
C |
T |
A |
G |
T |
C |
C |
G |
G |
T |
A |
C |
A |
2 |
C |
T |
2 |
T |
T |
T |
2 |
T |
C |
G |
T |
A |
T |
G |
C |
C |
G |
G |
G |
G |
G |
G |
A |
A |
A |
A |
2 |
C |
C |
T |
A |
C |
A |
C |
A |
A |
G |
C |
A |
C |
A |
C |
T |
G |
A |
T |
A |
T |
A |
T |
4 |
T |
C |
8 |
C |
A |
A |
A |
C |
4 |
G |
10 |
A |
T |
2 |
T |
T |
T |
5 |
G |
2 |
C |
C |
G |
G |
C |
G |
G |
2 |
G |
A |
A |
4 |
C |
C |
T |
T |
G |
A |
2 |
A |
A |
G |
C |
C |
G |
G |
C |
A |
A |
C |
T |
C |
T |
T |
T |
A |
T |
C |
T |
T |
2 |
G |
A |
A |
C |
T |
T |
C |
G |
A |
G |
G |
T |
4 |
A |
A |
A |
A |
A |
A |
A |
A |
A |
A |
A |
A |
A |
A |
A |
A |
A |
A |
G |
C |
C |
G |
G |
T |
G |
2 |
C |
G |
C |
T |
G |
T |
C |
G |
G |
T |
T |
T |
2 |
2 |
4 |
T |
2 |
A |
G |
C |
T |
A |
C |
T |
T |
A |
G |
C |
G |
A |
T |
C |
8 |
7 |
T |
G |
4 |
A |
C |
A |
G |
2 |
2 |
C |
A |
G |
T |
C |
C |
T |
A |
G |
C |
C |
3 |
G |
A |
T |
C |
G |
T |
T |
G |
A |
A |
T |
C |
C |
T |
G |
A |
G |
T |
T |
C |
A |
C |
C |
A |
G |
C |
A |
A |
A |
C |
A |
G |
C |
10 |
2 |
C |
T |
C |
C |
C |
T |
C |
A |
T |
C |
T |
C |
C |
T |
C |
A |
T |
T |
2 |
G |
C |
4 |
4 |
C |
G |
T |
C |
C |
A |
T |
C |
6 |
T |
2 |
A |
T |
C |
C |
G |
T |
7 |
4 |
2 |
A |
T |
T |
C |
A |
T |
T |
C |
2 |
C |
T |
T |
A |
G |
T |
T |
3 |
C |
C |
G |
G |
A |
G |
G |
G |
G |
T |
G |
9 |
8 |
G |
G |
T |
A |
T |
C |
A |
C |
T |
G |
2 |
2 |
4 |
2 |
2 |
2 |
2 |
C |
4 |
2 |
A |
4 |
A |
T |
A |
G |
C |
T |
C |
A |
A |
A |
A |
G |
C |
C |
T |
G |
G |
G |
T |
G |
G |
T |
C |
C |
G |
A |
A |
A |
G |
C |
C |
A |
G |
A |
4 |
2 |
2 |
C |
G |
A |
T |
A |
T |
C |
C |
C |
T |
|
|
|
|
|
|
|
|
|
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|
|
|
|
|
|
|
|
|
C
|
5
|
5
|
C
|
-
|
8/-
|
2
|
A/C
|
G
|
-
|
-
|
T
|
A
|
T
|
C
|
G
|
-
|
C/3
|
G
|
C
|
A
|
G
|
T
|
G
|
C
|
T
|
T
|
5
|
T/A
|
-
|
5/7
|
10/-
|
8/-
|
-
|
T
|
G
|
C
|
-/GA
|
2/-
|
3
|
CT/3
|
C
|
T/3
|
2/-
|
G
|
G
|
-
|
T
|
2
|
G
|
C
|
4
|
-
|
2
|
3
|
-
|
-
|
C
|
C
|
G
|
G
|
-
|
A
|
A
|
2
|
A
|
A
|
C
|
G
|
C
|
A
|
2
|
C
|
C
|
-
|
-
|
C
|
C
|
C
|
T
|
-
|
A/5
|
2
|
C
|
A
|
A
|
G
|
C
|
A
|
G
|
G
|
A
|
A
|
A
|
A
|
T
|
G
|
11
|
C
|
A
|
T
|
A
|
G
|
G
|
C
|
T
|
A
|
T
|
4/-
|
-
|
C
|
G
|
-
|
4/3
|
C/T
|
G/A
|
-
|
A
|
G
|
G
|
C
|
T
|
4
|
T
|
2
|
G
|
A/3
|
2
|
T
|
T
|
C
|
A
|
-
|
-
|
T
|
T
|
C
|
G
|
T
|
G
|
A
|
A
|
T
|
G
|
A
|
C
|
T
|
-
|
-
|
T
|
5
|
C
|
C
|
T
|
G
|
-
|
C
|
T
|
G
|
2
|
A
|
A
|
C
|
G
|
G
|
C
|
T
|
C
|
G
|
3
|
G
|
T
|
T
|
C
|
T
|
C
|
-
|
T
|
2
|
-
|
T
|
5
|
2/-
|
T/C
|
T/3
|
T/C
|
2/-
|
C
|
T
|
5
|
G
|
G
|
C
|
A
|
T
|
T
|
A
|
A
|
G/A
|
2
|
A
|
A
|
G
|
G
|
2
|
G
|
-
|
C/T
|
T
|
3
|
2
|
C/T
|
-
|
C/T
|
A/2
|
T
|
2
|
T
|
2
|
C/A
|
G
|
G
|
C
|
A
|
G
|
2
|
G
|
C
|
G
|
4
|
-
|
T/C
|
5/-
|
8/-
|
C/T
|
A/2
|
A/2
|
T/AT
|
5
|
-
|
A
|
-
|
A/G
|
7
|
2/-
|
5
|
C
|
C
|
-
|
3
|
-
|
3
|
5
|
G/3
|
G/C
|
C/A
|
G/-
|
G/3
|
-
|
C
|
2
|
G
|
-
|
C/T
|
C/T
|
T/C
|
T/C
|
T
|
G
|
-
|
G
|
T
|
6
|
-
|
CA/3
|
A
|
3
|
5/3
|
-
|
A/G
|
T
|
G
|
T
|
C
|
T/G
|
C
|
G
|
A
|
A
|
C
|
T/C
|
-
|
A
|
G
|
G
|
G
|
C
|
G
|
2
|
2
|
G
|
2
|
6/5
|
C
|
4/-
|
2
|
-/AC
|
2
|
2
|
2
|
2
|
2
|
2
|
2
|
2
|
2
|
2
|
2
|
2
|
-
|
A/4
|
A/4
|
-/AC
|
G/A
|
C/-
|
C/G
|
A
|
G/-
|
T/G
|
G/T
|
2/-
|
C/T
|
G/-
|
T
|
C
|
T
|
C
|
T
|
C
|
C
|
C
|
A
|
C
|
-
|
-
|
-
|
-
|
-
|
9
|
G/2
|
T
|
-
|
G
|
T
|
C
|
A
|
T
|
A
|
3
|
C
|
G
|
-
|
G
|
-
|
7/-
|
A
|
A
|
-
|
C
|
T
|
T
|
A
|
-
|
-
|
T
|
G
|
A
|
C
|
T
|
T
|
C
|
-
|
T
|
T
|
T
|
-
|
A
|
2
|
C
|
T
|
T
|
C
|
G
|
T
|
T
|
C
|
C
|
T
|
T
|
-
|
A
|
G
|
2
|
C
|
3
|
T
|
G
|
G
|
A
|
G
|
A
|
A
|
G
|
C
|
G
|
T
|
-
|
A
|
T
|
10/-
|
-
|
3/CA
|
T/-
|
5
|
2
|
5
|
T/C
|
C/2
|
G
|
G
|
T
|
T/G
|
A
|
T
|
C
|
T
|
4
|
3
|
2
|
-
|
-
|
C/G
|
-
|
-
|
T
|
T
|
3
|
T
|
A
|
T
|
C
|
T
|
-
|
T/C
|
-
|
2
|
3
|
T
|
T
|
T
|
T/-
|
7/-
|
4/-
|
2/-
|
G
|
C
|
C
|
T
|
C
|
C
|
C
|
T
|
2/-
|
-
|
C
|
C
|
G
|
T
|
C
|
C
|
-
|
T
|
G
|
A
|
A
|
G
|
A
|
C
|
C
|
C
|
-
|
C
|
9/-
|
8/-
|
5
|
5
|
C
|
3
|
C
|
T
|
T
|
A
|
A
|
G/C
|
2/-
|
2/-
|
4/-
|
2/-
|
2/-
|
2/-
|
2/-
|
C/T
|
4/-
|
-
|
A/5
|
4/-
|
G
|
C
|
G
|
T
|
T
|
A
|
T
|
G
|
G
|
T
|
G
|
A
|
A
|
3
|
C
|
C
|
A
|
C
|
G
|
A
|
T
|
A
|
3
|
T
|
A
|
G
|
G
|
G
|
A
|
G
|
T
|
C
|
A
|
2
|
-
|
-
|
-
|
T
|
A
|
G
|
A
|
G
|
C
|
T
|
G
|
T
|
2
|
|