|
-- |
.0 |
.241 |
.227 |
.002 |
.167 |
.127 |
.016 |
.062 |
.003 |
.025 |
.015 |
.107 |
-- |
-- |
.005 |
.026 |
.039 |
.048 |
.0 |
.108 |
.001 |
.0 |
.0 |
.004 |
.019 |
.0 |
.006 |
.003 |
.032 |
.041 |
.041 |
.13 |
.047 |
.774 |
.0 |
.0 |
.008 |
.159 |
.29 |
.002 |
.013 |
.007 |
-- |
-- |
.036 |
.002 |
.003 |
.232 |
.061 |
-- |
.808 |
.008 |
.548 |
.008 |
.04 |
.008 |
.239 |
.056 |
.01 |
.004 |
.283 |
.567 |
.055 |
.0 |
-- |
.005 |
.001 |
.059 |
.002 |
.133 |
.102 |
.04 |
.04 |
.0 |
.001 |
.002 |
.013 |
.001 |
.034 |
.005 |
.021 |
.002 |
.004 |
.007 |
.025 |
.009 |
.052 |
.008 |
.0 |
.022 |
.148 |
.014 |
.001 |
.983 |
.269 |
.045 |
.001 |
.001 |
.157 |
.0 |
.018 |
.001 |
.066 |
.003 |
.001 |
.139 |
.002 |
.526 |
.004 |
.003 |
.001 |
.0 |
.261 |
.018 |
.02 |
.129 |
.147 |
.089 |
.033 |
-- |
.005 |
.001 |
.051 |
.103 |
.054 |
.009 |
-- |
.207 |
.014 |
-- |
.054 |
.01 |
.126 |
.016 |
.003 |
.003 |
.001 |
.006 |
.006 |
.044 |
.185 |
.254 |
.048 |
.0 |
.001 |
.87 |
.152 |
-- |
-- |
.075 |
.001 |
.138 |
.0 |
.0 |
.0 |
.0 |
1.0 |
.012 |
.005 |
.768 |
.055 |
.015 |
.5 |
.084 |
.002 |
.001 |
.003 |
.014 |
.166 |
.057 |
.016 |
.266 |
.168 |
.179 |
.716 |
.111 |
.404 |
.004 |
.001 |
.001 |
.092 |
.063 |
.106 |
.101 |
.001 |
.004 |
.01 |
.106 |
.003 |
-- |
-- |
.998 |
1.0 |
.531 |
.002 |
.005 |
.003 |
.002 |
.004 |
.177 |
.015 |
.001 |
.001 |
.0 |
.007 |
.001 |
.025 |
.021 |
.002 |
.0 |
.001 |
.0 |
.002 |
.005 |
.003 |
.003 |
.121 |
.011 |
.116 |
.161 |
.003 |
.462 |
.004 |
.007 |
.002 |
.002 |
.55 |
.191 |
.001 |
.067 |
.009 |
-- |
-- |
.044 |
.229 |
.007 |
.151 |
.001 |
.003 |
.001 |
.003 |
-- |
.239 |
.029 |
.051 |
.013 |
.019 |
.077 |
.031 |
.023 |
.009 |
.008 |
.004 |
.946 |
.001 |
.012 |
.777 |
.004 |
.996 |
.998 |
.995 |
.06 |
.022 |
.0 |
.001 |
.98 |
.21 |
-- |
.02 |
.005 |
.002 |
.0 |
.0 |
.0 |
.0 |
.0 |
.0 |
.007 |
.005 |
.012 |
.016 |
.041 |
.466 |
.112 |
.019 |
.001 |
.705 |
-- |
.019 |
.006 |
.002 |
.008 |
.009 |
.001 |
.005 |
.154 |
.0 |
.274 |
.003 |
.01 |
.001 |
.001 |
.007 |
.031 |
.022 |
.0 |
.0 |
.005 |
.036 |
.009 |
.024 |
.666 |
.507 |
.011 |
.105 |
.209 |
.0 |
.004 |
.002 |
.01 |
.003 |
.002 |
.056 |
.0 |
.01 |
.012 |
.0 |
.0 |
.001 |
.008 |
.002 |
.0 |
.001 |
-- |
.017 |
.316 |
.018 |
.009 |
.014 |
.074 |
.08 |
.05 |
.008 |
.04 |
.073 |
.093 |
.094 |
.0 |
.004 |
.006 |
.001 |
1.0 |
|
Atg7
|
Atg7
|
Atg7
|
Atg7
|
Atg7
|
Atg7
|
Atg7
|
Atg7
|
Atg7
|
Atg7
|
Atg7
|
Atg7
|
Atg7
|
Atg7
|
Atg7
|
Atg7
|
Atg7
|
Atg7
|
Atg7
|
Atg7
|
Atg7
|
Atg7
|
Atg7
|
Atg7
|
Atg7
|
Atg7
|
Atg7
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|
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|
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|
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|
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|
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|
Atg7
|
Atg7
|
|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
--
|
--
|
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|
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|
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|
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|
--
|
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|
--
|
--
|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
--
|
--
|
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|
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|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
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|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
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|
--
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|
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|
--
|
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|
--
|
--
|
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--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
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--
|
--
|
--
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--
|
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|
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|
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|
--
|
--
|
--
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--
|
--
|
--
|
--
|
--
|
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|
--
|
--
|
--
|
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--
|
--
|
--
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--
|
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|
--
|
--
|
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|
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|
--
|
--
|
--
|
--
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|
--
|
--
|
--
|
--
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--
|
--
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--
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--
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--
|
--
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|
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--
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|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
|
G |
C |
2 |
T |
A |
T |
A |
T |
3 |
A |
A |
C |
A |
T |
A |
A |
C |
C |
A |
T |
G |
C |
C |
T |
T |
C |
C |
A |
G |
C |
T |
T |
C |
C |
C |
A |
C |
G |
T |
T |
A |
A |
C |
A |
G |
C |
A |
T |
C |
C |
A |
G |
T |
G |
T |
G |
A |
G |
C |
A |
A |
C |
A |
A |
T |
G |
G |
T |
A |
G |
T |
T |
T |
C |
C |
C |
C |
T |
C |
A |
A |
A |
A |
G |
T |
4 |
T |
A |
C |
A |
C |
C |
T |
G |
C |
C |
G |
G |
T |
T |
G |
A |
G |
C |
G |
T |
A |
A |
C |
A |
T |
A |
G |
A |
A |
G |
G |
C |
G |
C |
A |
G |
C |
T |
C |
A |
C |
A |
G |
106 |
A |
G |
C |
A |
C |
G |
G |
G |
G |
T |
G |
C |
G |
8 |
T |
A |
C |
C |
A |
G |
A |
C |
C |
T |
A |
A |
A |
A |
G |
T |
C |
G |
G |
A |
T |
A |
C |
T |
G |
A |
T |
A |
G |
C |
C |
T |
T |
C |
C |
T |
A |
G |
A |
T |
C |
C |
G |
G |
G |
C |
C |
G |
G |
A |
A |
A |
C |
A |
A |
G |
T |
T |
T |
C |
A |
A |
A |
A |
G |
T |
A |
G |
T |
A |
T |
T |
T |
A |
A |
C |
G |
A |
A |
3 |
A |
2 |
T |
C |
G |
A |
C |
A |
20 |
G |
T |
G |
G |
G |
C |
G |
A |
A |
A |
C |
A |
3 |
C |
A |
G |
C |
T |
A |
C |
C |
C |
C |
6 |
G |
A |
T |
G |
G |
C |
A |
A |
G |
G |
A |
C |
A |
C |
T |
G |
T |
C |
T |
C |
A |
8 |
G |
A |
T |
T |
G |
A |
A |
T |
G |
6 |
4 |
A |
C |
T |
A |
G |
C |
24 |
G |
A |
T |
C |
G |
G |
G |
A |
A |
G |
G |
C |
T |
G |
G |
T |
G |
C |
T |
94 |
C |
A |
C |
A |
C |
A |
C |
A |
6 |
A |
C |
C |
G |
A |
C |
T |
G |
T |
C |
C |
G |
A |
G |
G |
A |
T |
A |
G |
A |
T |
T |
A |
G |
2 |
T |
9 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
T
|
T
|
2/-
|
T/C
|
G
|
2
|
T
|
2
|
-
|
T
|
T
|
3
|
C
|
C
|
A/G
|
G
|
T
|
T
|
G
|
A
|
A
|
G
|
T
|
A
|
-
|
A
|
T
|
A/G
|
G/A
|
T
|
A
|
C
|
T
|
A
|
T
|
G
|
T
|
T
|
C
|
C
|
G
|
G
|
C/T
|
C
|
C
|
G
|
G
|
A
|
A
|
T
|
T
|
A
|
T/A
|
A
|
C
|
A
|
-
|
A
|
T
|
T
|
G
|
T
|
T
|
T
|
C
|
A
|
A
|
T/11
|
-
|
A
|
C
|
T/4
|
T/C
|
T
|
G
|
T
|
T
|
T/C
|
A
|
-
|
G
|
2
|
T
|
A
|
C
|
-
|
C
|
G
|
T
|
G
|
C/T
|
T
|
C
|
C
|
T
|
T
|
A
|
A
|
G
|
C
|
A
|
G
|
A
|
T
|
A
|
C
|
G
|
G
|
3
|
G
|
T/-
|
A/G
|
C
|
C
|
G
|
A
|
A
|
T
|
A
|
C/T
|
G
|
A
|
T
|
C
|
C/-
|
G
|
G
|
A/2
|
G/26
|
106/-
|
G
|
C
|
T
|
G
|
G
|
A
|
A
|
T
|
A
|
-
|
T
|
T
|
A
|
-
|
2
|
G
|
T
|
T
|
C
|
C
|
2
|
A
|
T
|
C
|
C
|
G
|
G
|
C
|
A
|
C
|
T
|
C
|
A
|
G
|
-
|
A/G
|
A
|
A
|
A
|
T
|
-
|
C
|
A
|
T
|
G
|
A
|
A
|
A
|
T
|
T/C
|
2
|
A
|
G
|
C
|
A
|
C/T
|
A
|
A
|
A
|
T
|
T
|
T
|
T
|
A/T
|
A/G
|
G
|
T
|
T
|
C
|
A
|
C
|
C
|
C
|
T
|
G
|
C
|
G
|
G
|
A
|
C
|
G
|
A
|
A
|
G
|
A
|
G
|
C
|
G
|
G
|
G
|
A
|
G
|
A/G
|
3/-
|
G
|
-
|
G
|
T
|
A
|
G
|
T
|
G
|
20/-
|
G/6
|
3
|
A
|
T
|
A
|
T
|
T
|
C
|
C
|
G
|
G
|
A/G
|
-
|
G
|
T
|
-
|
A
|
C
|
C
|
A
|
A
|
20
|
T
|
-
|
C
|
C
|
2
|
A
|
A
|
A
|
T
|
2
|
A
|
A
|
T
|
3
|
G
|
-
|
C
|
A
|
T/2
|
T
|
C
|
G
|
G
|
8/-
|
A
|
A/2
|
2
|
C
|
A
|
T
|
G
|
G
|
A
|
-
|
-
|
-
|
A
|
A
|
-
|
2
|
T
|
-
|
A
|
G
|
C
|
T
|
G/C
|
G/C
|
-
|
G
|
G
|
G/A
|
G/C
|
G
|
C
|
A
|
A
|
G
|
G/A
|
G
|
C
|
94/-
|
T
|
A/G
|
G
|
A/T
|
T
|
A/29
|
T
|
-
|
-
|
C
|
T
|
T
|
A
|
A/G
|
T
|
C
|
A
|
G
|
T
|
T
|
A
|
T
|
A
|
T
|
G
|
C
|
C
|
A
|
G
|
-
|
A
|
T
|
A
|
-
|
2
|
-
|
|