|
.154 |
.016 |
-- |
.024 |
.094 |
.073 |
-- |
.433 |
.067 |
.019 |
.038 |
.032 |
.017 |
.815 |
.827 |
.816 |
.383 |
.206 |
.133 |
.029 |
.017 |
.008 |
.09 |
.022 |
.021 |
.517 |
-- |
-- |
-- |
-- |
.156 |
.013 |
.279 |
.033 |
-- |
.018 |
.01 |
.924 |
.121 |
.053 |
.019 |
.008 |
.005 |
.0 |
.003 |
.013 |
.023 |
.005 |
.002 |
.077 |
.003 |
.058 |
.011 |
.049 |
.007 |
.008 |
.022 |
.716 |
.014 |
.014 |
.181 |
.103 |
1.0 |
.004 |
.116 |
.004 |
.021 |
.398 |
.741 |
.026 |
.009 |
.0 |
.048 |
.024 |
.031 |
.002 |
.019 |
.058 |
.014 |
.188 |
.121 |
.011 |
.0 |
.007 |
.004 |
.0 |
-- |
-- |
-- |
-- |
-- |
-- |
.05 |
.021 |
.009 |
.001 |
.0 |
.032 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
.934 |
.656 |
.137 |
.005 |
.115 |
.036 |
.008 |
.002 |
.977 |
-- |
-- |
-- |
.02 |
.017 |
.086 |
.051 |
.314 |
.008 |
.212 |
-- |
-- |
.004 |
.242 |
.004 |
.002 |
.007 |
.071 |
.001 |
.107 |
.008 |
.998 |
.902 |
.921 |
-- |
-- |
-- |
-- |
-- |
-- |
.012 |
.004 |
-- |
.041 |
.294 |
.013 |
.006 |
-- |
.061 |
.053 |
.065 |
.002 |
.004 |
.017 |
.001 |
.214 |
.878 |
.0 |
-- |
.001 |
.0 |
.034 |
.01 |
.013 |
.155 |
.148 |
.01 |
.047 |
.016 |
.002 |
.012 |
.01 |
.006 |
.003 |
.015 |
.01 |
.064 |
.031 |
.546 |
.011 |
.107 |
.06 |
.948 |
.011 |
.001 |
.033 |
.326 |
.107 |
.136 |
.063 |
.048 |
.134 |
.014 |
.001 |
.3 |
.009 |
.001 |
.216 |
.171 |
.066 |
.02 |
.02 |
.017 |
.001 |
.196 |
.09 |
.0 |
-- |
-- |
-- |
-- |
.075 |
.001 |
.014 |
.133 |
.037 |
.98 |
.104 |
.098 |
.015 |
.007 |
.009 |
.009 |
.019 |
.007 |
.003 |
.001 |
.01 |
.002 |
.001 |
.006 |
.002 |
.068 |
-- |
.001 |
.196 |
.014 |
.021 |
.072 |
.097 |
.048 |
.001 |
.002 |
.223 |
.004 |
.003 |
.031 |
.008 |
.103 |
.038 |
.001 |
.0 |
.007 |
.897 |
.001 |
.012 |
.004 |
.036 |
.0 |
.002 |
.996 |
.996 |
.008 |
.009 |
.003 |
.033 |
.074 |
.003 |
.0 |
.005 |
.009 |
.0 |
.057 |
.001 |
.006 |
.001 |
.033 |
.048 |
.025 |
.024 |
.001 |
-- |
.023 |
.848 |
-- |
-- |
.006 |
.019 |
.027 |
.082 |
.002 |
.001 |
.997 |
|
Atg5
|
Atg5
|
Atg5
|
Atg5
|
Atg5
|
Atg5
|
Atg5
|
Atg5
|
Atg5
|
Atg5
|
Atg5
|
Atg5
|
Atg5
|
Atg5
|
Atg5
|
Atg5
|
Atg5
|
Atg5
|
Atg5
|
Atg5
|
Atg5
|
Atg5
|
Atg5
|
Atg5
|
Atg5
|
Atg5
|
Atg5
|
Atg5
|
Atg5
|
Atg5
|
Atg5
|
|
--
|
--
|
--
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--
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--
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--
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--
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--
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--
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|
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--
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--
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--
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--
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--
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--
|
--
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--
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--
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--
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--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
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--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
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--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
|
C |
A |
G |
A |
T |
G |
G |
A |
C |
C |
G |
G |
A |
T |
T |
A |
C |
T |
A |
A |
A |
A |
T |
A |
G |
C |
C |
G |
C |
G |
C |
A |
T |
G |
T |
A |
A |
C |
T |
T |
A |
4 |
G |
G |
T |
T |
A |
C |
T |
C |
G |
T |
A |
G |
A |
A |
G |
T |
A |
G |
A |
T |
C |
8 |
T |
G |
G |
T |
G |
G |
A |
C |
G |
A |
G |
C |
T |
G |
C |
5 |
T |
A |
T |
C |
C |
A |
G |
10 |
7 |
T |
G |
T |
T |
C |
G |
T |
G |
T |
T |
C |
C |
A |
G |
C |
A |
4 |
T |
A |
G |
C |
G |
G |
T |
G |
A |
C |
T |
G |
C |
G |
T |
G |
G |
A |
C |
G |
G |
T |
A |
G |
G |
T |
C |
T |
A |
A |
C |
A |
T |
2 |
A |
G |
G |
A |
A |
A |
C |
T |
T |
G |
C |
9 |
G |
2 |
4 |
T |
C |
C |
A |
A |
G |
3 |
A |
C |
A |
G |
T |
G |
A |
T |
C |
A |
C |
A |
A |
G |
G |
T |
T |
G |
5 |
C |
A |
T |
C |
C |
T |
C |
C |
G |
T |
A |
A |
A |
T |
T |
C |
A |
G |
G |
T |
T |
C |
C |
A |
A |
A |
A |
C |
T |
T |
T |
A |
G |
G |
A |
G |
G |
C |
A |
C |
A |
A |
T |
A |
G |
C |
A |
A |
A |
A |
A |
G |
G |
G |
A |
G |
T |
G |
C |
T |
T |
A |
2 |
T |
T |
A |
T |
A |
G |
A |
C |
G |
G |
G |
C |
T |
T |
A |
G |
T |
A |
T |
C |
C |
T |
A |
G |
C |
A |
G |
A |
T |
G |
T |
G |
G |
T |
A |
2 |
C |
T |
G |
A |
A |
C |
G |
T |
T |
A |
A |
T |
C |
A |
C |
A |
3 |
G |
G |
A |
G |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
T
|
G
|
4/3
|
T
|
A
|
A
|
A
|
G
|
A
|
T
|
G/A
|
A
|
C
|
G
|
A
|
G
|
2
|
T/2
|
T
|
T
|
G
|
G
|
A
|
G
|
A
|
A
|
A
|
A
|
T
|
73
|
T
|
G
|
5
|
A
|
5
|
G
|
G
|
-
|
A
|
C
|
G
|
4/-
|
C
|
-
|
-
|
C
|
G
|
-
|
T/C
|
T
|
3
|
C
|
G
|
A
|
A/2
|
G
|
A
|
A
|
G
|
T
|
C
|
-
|
6
|
-
|
2
|
-
|
T
|
C
|
A
|
A
|
G
|
8
|
A
|
G
|
G/A
|
T
|
T/G
|
A
|
G
|
-
|
C
|
G
|
C
|
T
|
T
|
G
|
A
|
-
|
-
|
A
|
A
|
C
|
C
|
G
|
A
|
C
|
A
|
-
|
A
|
A
|
T
|
G
|
A
|
T
|
G
|
-
|
C
|
G
|
A
|
G
|
A
|
-
|
C
|
A
|
G
|
T
|
A
|
A
|
G
|
C
|
C
|
A
|
A
|
G
|
T
|
A
|
A
|
7
|
-
|
A
|
A
|
C
|
A
|
C
|
C
|
G
|
C/3
|
T
|
C
|
-
|
G
|
T
|
15
|
G
|
G
|
C
|
T
|
C
|
C
|
A
|
T
|
9/-
|
A
|
-
|
-
|
C
|
T
|
T
|
T
|
T
|
A
|
-
|
T
|
T
|
G
|
T
|
A
|
A
|
G
|
C
|
T
|
G
|
T
|
G
|
G
|
2
|
T
|
C
|
C
|
A
|
5/-
|
C/T
|
T
|
T/30
|
T
|
C/T
|
C
|
T
|
G
|
A
|
A
|
G
|
G
|
G
|
C
|
C
|
A
|
G
|
A
|
A
|
C
|
-
|
C/T
|
G
|
A/G
|
A/G
|
A/G
|
G
|
T
|
G
|
C
|
A
|
G
|
A
|
A
|
C
|
A
|
16
|
-
|
2
|
T
|
G
|
G
|
C
|
G
|
C
|
G
|
C
|
T
|
T
|
G
|
T
|
A
|
C
|
A
|
G
|
C
|
C
|
G/A
|
C/T
|
C
|
C
|
G
|
-
|
C
|
C
|
G
|
C
|
T
|
A
|
G
|
A
|
A
|
A
|
A
|
T
|
A
|
C
|
G
|
C
|
4
|
T
|
C
|
T
|
T
|
C
|
T
|
C
|
C/T
|
G
|
3
|
C
|
T/C
|
G/A
|
T/2
|
T
|
G/T
|
T/A
|
3
|
2/-
|
-
|
C
|
A
|
G
|
G
|
G
|
-
|
6
|
C
|
2
|
G
|
G
|
-
|
C
|
G
|
-
|
3/-
|
C
|
A
|
C
|
A
|
|