|
.001 |
.012 |
.435 |
.004 |
.002 |
.016 |
.115 |
.015 |
.011 |
.004 |
.096 |
.155 |
.026 |
.015 |
.048 |
.137 |
.107 |
.043 |
.038 |
.025 |
.019 |
.007 |
.003 |
.032 |
.092 |
.168 |
.009 |
.029 |
.0 |
.022 |
.051 |
.195 |
.0 |
.009 |
.012 |
-- |
.087 |
.001 |
.056 |
.082 |
.061 |
.023 |
.003 |
-- |
-- |
-- |
-- |
.019 |
.005 |
.012 |
.077 |
.037 |
.001 |
.001 |
.011 |
.023 |
.002 |
.001 |
.036 |
.05 |
.004 |
.084 |
.028 |
-- |
.007 |
.034 |
.001 |
.006 |
.0 |
.0 |
.0 |
.197 |
.138 |
-- |
-- |
.573 |
.007 |
.001 |
.516 |
.069 |
-- |
-- |
-- |
.104 |
.006 |
.017 |
.004 |
.005 |
.019 |
.15 |
.084 |
.258 |
.019 |
.343 |
.004 |
.014 |
.018 |
.014 |
.4 |
.532 |
.005 |
.094 |
.095 |
.483 |
.029 |
.002 |
-- |
-- |
.019 |
.016 |
.007 |
.032 |
.138 |
.004 |
.512 |
.131 |
.402 |
.157 |
.215 |
.445 |
.072 |
.005 |
.013 |
.024 |
.009 |
.002 |
.029 |
.001 |
.001 |
.05 |
.115 |
.122 |
-- |
.025 |
.0 |
.0 |
.157 |
.228 |
.002 |
.058 |
.601 |
-- |
.263 |
.03 |
.001 |
.058 |
.008 |
.006 |
.017 |
.005 |
-- |
.013 |
.001 |
.063 |
.015 |
.072 |
.008 |
.065 |
.01 |
.002 |
.02 |
.008 |
.083 |
.095 |
.023 |
.032 |
.029 |
.008 |
.994 |
-- |
.001 |
.038 |
.013 |
.007 |
.163 |
.131 |
.525 |
.003 |
.002 |
.152 |
.038 |
.016 |
.057 |
.004 |
.016 |
.002 |
.981 |
.0 |
.028 |
.006 |
.047 |
.161 |
.209 |
.227 |
.172 |
.142 |
.156 |
.652 |
-- |
-- |
.036 |
.041 |
.055 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
.259 |
.0 |
.001 |
.282 |
.549 |
.936 |
.47 |
.14 |
.018 |
.011 |
.016 |
.012 |
.004 |
.053 |
.024 |
.001 |
.578 |
.0 |
.002 |
.001 |
.021 |
.01 |
.103 |
.008 |
.076 |
.003 |
.0 |
.01 |
.115 |
.004 |
.002 |
.006 |
.005 |
.004 |
.0 |
.002 |
.0 |
.001 |
.0 |
.003 |
.123 |
.018 |
.06 |
.002 |
.01 |
-- |
.014 |
.085 |
-- |
.001 |
.01 |
.052 |
.028 |
.014 |
-- |
.057 |
.0 |
-- |
.079 |
.008 |
.187 |
.058 |
.06 |
.328 |
-- |
.018 |
-- |
.971 |
.008 |
-- |
.005 |
.086 |
|
Cacna1a
|
Cacna1a
|
Cacna1a
|
Cacna1a
|
Cacna1a
|
Cacna1a
|
Cacna1a
|
Cacna1a
|
Cacna1a
|
Cacna1a
|
Cacna1a
|
Cacna1a
|
Cacna1a
|
Cacna1a
|
Cacna1a
|
Cacna1a
|
Cacna1a
|
Cacna1a
|
Cacna1a
|
Cacna1a
|
Cacna1a
|
Cacna1a
|
Cacna1a
|
Cacna1a
|
Cacna1a
|
Cacna1a
|
Cacna1a
|
Cacna1a
|
Cacna1a
|
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
|
G |
A |
A |
A |
2 |
T |
C |
T |
G |
G |
A |
T |
G |
C |
A |
G |
C |
C |
C |
A |
C |
G |
C |
G |
G |
4 |
C |
G |
G |
C |
G |
A |
A |
T |
G |
T |
G |
G |
T |
T |
C |
C |
C |
G |
T |
G |
A |
C |
T |
T |
T |
C |
C |
C |
A |
T |
T |
G |
A |
A |
A |
T |
T |
2 |
G |
A |
C |
C |
A |
T |
A |
C |
C |
G |
A |
G |
A |
A |
6 |
T |
A |
A |
108 |
A |
C |
T |
G |
G |
T |
T |
C |
C |
G |
C |
G |
C |
T |
A |
G |
T |
G |
G |
C |
G |
C |
A |
T |
C |
T |
C |
G |
C |
A |
T |
T |
A |
A |
A |
T |
G |
A |
C |
C |
G |
G |
T |
G |
A |
C |
T |
T |
A |
G |
G |
A |
T |
C |
T |
C |
T |
A |
A |
A |
A |
G |
A |
G |
C |
G |
C |
A |
T |
T |
G |
G |
A |
T |
T |
G |
C |
170 |
A |
T |
T |
G |
G |
C |
T |
T |
24 |
T |
G |
G |
C |
C |
G |
A |
C |
A |
G |
C |
G |
G |
C |
A |
T |
G |
T |
A |
C |
A |
C |
T |
G |
A |
G |
T |
C |
G |
C |
G |
T |
C |
C |
C |
G |
T |
G |
C |
C |
A |
G |
T |
A |
C |
T |
C |
G |
A |
A |
G |
C |
G |
G |
C |
C |
G |
A |
G |
G |
A |
C |
A |
A |
A |
C |
C |
G |
G |
A |
C |
A |
A |
A |
G |
G |
A |
A |
A |
T |
A |
T |
G |
T |
A |
6 |
G |
A |
T |
G |
G |
G |
T |
C |
T |
A |
T |
C |
3 |
A |
G |
C |
5 |
G |
A |
G |
G |
A |
T |
A |
G |
A |
C |
T |
G |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
T
|
G
|
G
|
-
|
-
|
A
|
G
|
T/C
|
A
|
A
|
A/5
|
G
|
A
|
T
|
G
|
A
|
G
|
T
|
T
|
G
|
T
|
G/A
|
T
|
T
|
A
|
-
|
T
|
2
|
A
|
T
|
G/A
|
G
|
G
|
C
|
A
|
G
|
G/16
|
A
|
4
|
A
|
A
|
T
|
T
|
C
|
C
|
A
|
G
|
T
|
C
|
C
|
C
|
G
|
G
|
A
|
G
|
T/C
|
-
|
A
|
A/G
|
G
|
G
|
C
|
C
|
-
|
T
|
G
|
T
|
T
|
G
|
C
|
G
|
T
|
T
|
5
|
G
|
G/A
|
A/G
|
G
|
-
|
G
|
G
|
A/G
|
-
|
C
|
C/G
|
C
|
2
|
2
|
T/C
|
A
|
T
|
G
|
A
|
T
|
T
|
T
|
G
|
G
|
A
|
3
|
A
|
C
|
T
|
A
|
C/T
|
G
|
-
|
C/-
|
C
|
T
|
G/A
|
T
|
2
|
C
|
T/C
|
C
|
A/G
|
4
|
T/C
|
2
|
G
|
T
|
T
|
A
|
T
|
G
|
2
|
G
|
T
|
C
|
C
|
C
|
A
|
A
|
A/G
|
A
|
C/11
|
2
|
C/G
|
C
|
C
|
A/5
|
C
|
G
|
A
|
A/G
|
T
|
T
|
A
|
T
|
G
|
T/7
|
C
|
G/-
|
G/A
|
G
|
C
|
C
|
A
|
T
|
-
|
G
|
C
|
T/G
|
G/T
|
G/C
|
T
|
C
|
C
|
-
|
T/C
|
A
|
-
|
T
|
T
|
T
|
T
|
T
|
G
|
A
|
C/T
|
G/A
|
A
|
T
|
A/G
|
C
|
A
|
C
|
G
|
2
|
G
|
C/2
|
T/3
|
A
|
-
|
3
|
C
|
T
|
T
|
C/T
|
A
|
G
|
A
|
T
|
G
|
A
|
G
|
T
|
G
|
G
|
G
|
G/3
|
C
|
G
|
5
|
C
|
C/T
|
A
|
T
|
G
|
A
|
T
|
A
|
G/A
|
2
|
C/T
|
A
|
A/G
|
T
|
G/T
|
G
|
2
|
A/G
|
G
|
G
|
C/A
|
C/T
|
-
|
A
|
T
|
T
|
G
|
G
|
G
|
T
|
T
|
G
|
G
|
2
|
C
|
C
|
G
|
C
|
C
|
-
|
-
|
A
|
C
|
C
|
T
|
A
|
G/C
|
2
|
-
|
T/C
|
G
|
C
|
6
|
-
|
T
|
4
|
T
|
-
|
C
|
5
|
A
|
A
|
A/2
|
A
|
C
|
A
|
G
|
T
|
C
|
A
|
|