|
.132 |
1.0 |
.0 |
.01 |
.0 |
.037 |
.004 |
.032 |
.013 |
.0 |
.685 |
.572 |
.029 |
.001 |
.0 |
.0 |
.001 |
.237 |
.0 |
.003 |
.011 |
.001 |
.0 |
.0 |
.003 |
.002 |
.0 |
.003 |
.003 |
-- |
.035 |
.001 |
.057 |
-- |
.466 |
-- |
.0 |
.0 |
.0 |
.017 |
.002 |
.001 |
.0 |
.062 |
.003 |
.0 |
.954 |
.998 |
.824 |
.126 |
.007 |
.008 |
.014 |
.001 |
.439 |
.139 |
.003 |
.009 |
.035 |
.037 |
.004 |
.001 |
.003 |
.005 |
.446 |
.002 |
.001 |
.024 |
.0 |
.023 |
.0 |
.006 |
.0 |
.006 |
.0 |
.075 |
.005 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
.0 |
.0 |
.01 |
.002 |
.001 |
.003 |
.306 |
-- |
-- |
.007 |
.081 |
.007 |
.0 |
.001 |
.002 |
.031 |
.004 |
.014 |
.0 |
.0 |
.002 |
.0 |
.014 |
.003 |
.129 |
.004 |
.0 |
.005 |
.001 |
.007 |
.005 |
.164 |
.01 |
.008 |
.233 |
.388 |
.001 |
.004 |
.024 |
.002 |
.112 |
.0 |
.001 |
.001 |
.001 |
-- |
-- |
-- |
.631 |
.001 |
.002 |
.014 |
.027 |
.0 |
.0 |
.006 |
.005 |
.127 |
.012 |
.005 |
.9 |
.013 |
.008 |
.0 |
.009 |
.01 |
.006 |
.002 |
.002 |
.002 |
.051 |
.012 |
.08 |
.242 |
.014 |
.21 |
.05 |
.001 |
.076 |
.01 |
.002 |
.0 |
.0 |
.001 |
.007 |
.002 |
.004 |
.008 |
.034 |
.031 |
.014 |
.219 |
.002 |
.04 |
.01 |
.023 |
.002 |
.054 |
-- |
-- |
-- |
.001 |
.002 |
.093 |
.398 |
.003 |
.001 |
.001 |
.0 |
.977 |
.991 |
.98 |
.984 |
-- |
-- |
-- |
-- |
-- |
.06 |
.094 |
.24 |
.132 |
.005 |
.0 |
.006 |
.002 |
.003 |
.002 |
.001 |
.576 |
.173 |
.071 |
.015 |
.008 |
.003 |
.411 |
.01 |
.013 |
.091 |
.05 |
.164 |
.011 |
.001 |
.001 |
.0 |
.002 |
.011 |
.849 |
.841 |
.006 |
.004 |
.001 |
.002 |
.007 |
.009 |
.051 |
.004 |
.004 |
.137 |
.094 |
.004 |
.0 |
.005 |
.015 |
.093 |
.003 |
.002 |
.001 |
.024 |
.045 |
.002 |
-- |
.002 |
.002 |
.007 |
.002 |
.055 |
.023 |
.009 |
.006 |
.017 |
.016 |
.032 |
.003 |
.003 |
.073 |
.031 |
.0 |
.12 |
.118 |
.1 |
.003 |
.042 |
.004 |
.003 |
.017 |
.042 |
.103 |
.002 |
.025 |
.005 |
.195 |
.013 |
.047 |
.054 |
.052 |
.006 |
.004 |
.038 |
.046 |
.011 |
.004 |
.003 |
.207 |
.005 |
.096 |
.002 |
.002 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
.008 |
.002 |
.001 |
.002 |
.019 |
.016 |
-- |
.099 |
.003 |
.002 |
.022 |
.006 |
.005 |
.004 |
.084 |
.004 |
.001 |
.005 |
.011 |
.037 |
.015 |
.006 |
.001 |
.055 |
.051 |
.189 |
.453 |
.08 |
.039 |
.003 |
.006 |
.017 |
.001 |
.727 |
.037 |
.043 |
.071 |
.186 |
.172 |
.002 |
.461 |
.019 |
.169 |
.009 |
.046 |
.001 |
.026 |
.004 |
.012 |
.0 |
.114 |
.738 |
.813 |
.968 |
.079 |
.116 |
.112 |
.0 |
.001 |
.001 |
.0 |
.0 |
.0 |
.001 |
.0 |
-- |
-- |
-- |
-- |
.004 |
.0 |
.0 |
.437 |
.002 |
.018 |
.001 |
.0 |
.0 |
.002 |
.149 |
.002 |
.028 |
.029 |
.012 |
.003 |
.001 |
.005 |
.001 |
.007 |
.0 |
.0 |
.003 |
.009 |
.0 |
.0 |
.001 |
.0 |
.0 |
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
|
Stxbp5
|
Stxbp5
|
Stxbp5
|
Stxbp5
|
Stxbp5
|
Stxbp5
|
Stxbp5
|
Stxbp5
|
Stxbp5
|
Stxbp5
|
Stxbp5
|
Stxbp5
|
Stxbp5
|
Stxbp5
|
Stxbp5
|
Stxbp5
|
Stxbp5
|
Stxbp5
|
Stxbp5
|
Stxbp5
|
Stxbp5
|
Stxbp5
|
Stxbp5
|
Stxbp5
|
Stxbp5
|
Stxbp5
|
Stxbp5
|
Stxbp5
|
Stxbp5
|
Stxbp5
|
Stxbp5
|
Stxbp5
|
Stxbp5
|
Stxbp5
|
Stxbp5
|
Stxbp5
|
Stxbp5
|
Stxbp5
|
Stxbp5
|
Stxbp5
|
Stxbp5
|
Stxbp5
|
Stxbp5
|
|
T |
C |
C |
C |
G |
C |
T |
G |
A |
T |
T |
G |
- |
A |
C |
T |
A |
A |
C |
T |
A |
A |
G |
A |
G |
A |
T |
A |
T |
G |
- |
T |
G |
2 |
G |
2 |
T |
A |
A |
T |
A |
A |
A |
- |
T |
C |
A |
A |
A |
A |
T |
G |
T |
21 |
- |
- |
T |
G |
G |
C |
T |
A |
T |
A |
120 |
A |
C |
C |
G |
G |
G |
C |
A |
C |
A |
A |
T |
G |
T |
A |
T |
A |
C |
T |
C |
T |
C |
T |
C |
G |
C |
T |
C |
T |
T |
A |
- |
2 |
C |
T |
T |
C |
T |
- |
A |
T |
A |
G |
G |
G |
T |
T |
T |
G |
T |
T |
G |
G |
G |
C |
C |
T |
11 |
G |
T |
T |
G |
2 |
T |
A |
T |
T |
A |
A |
G |
- |
T |
A |
G |
T |
- |
C |
T |
C |
A |
C |
G |
T |
A |
A |
G |
T |
2 |
- |
T |
C |
C |
2 |
A |
C |
T |
G |
- |
T |
C |
T |
T |
T |
A |
T |
T |
A |
T |
C |
T |
- |
C |
C |
G |
G |
T |
C |
G |
T |
4 |
G |
A |
A |
G |
G |
T |
T |
T |
- |
C |
4 |
T |
- |
A |
4 |
G |
2 |
C |
- |
G |
G |
G |
T |
T |
C |
G |
108 |
A |
G |
T |
T |
C |
T |
C |
C |
T |
C |
T |
A |
A |
G |
T |
- |
2 |
A |
C |
A |
T |
G |
A |
C |
A |
A |
G |
T |
A |
A |
35 |
A |
C |
G |
C |
A |
T |
G |
- |
T |
C |
T |
C |
C |
T |
A |
C |
T |
G |
G |
T |
C |
A |
G |
A |
C |
T |
C |
T |
G |
A |
A |
A |
7 |
C |
G |
T |
A |
T |
C |
G |
A |
G |
T |
G |
2 |
- |
T |
A |
G |
C |
A |
C |
C |
A |
T |
T |
T |
C |
C |
C |
A |
- |
A |
C |
G |
G |
G |
G |
A |
T |
C |
G |
T |
G |
4 |
G |
- |
C |
A |
A |
C |
A |
A |
- |
T |
13 |
6 |
T |
29 |
T |
T |
G |
G |
G |
- |
C |
G |
G |
G |
C |
A |
C |
T |
C |
T |
- |
T |
T |
A |
T |
A |
A |
C |
A |
C |
G |
C |
- |
T |
G |
T |
C |
G |
C |
T |
G |
T |
C |
G |
G |
T |
G |
A |
A |
T |
A |
G |
G |
G |
C |
T |
T |
T |
A |
C |
A |
A |
- |
G |
T |
A |
48 |
A |
C |
G |
T |
G |
T |
T |
G |
G |
G |
- |
T |
- |
A |
A |
C |
T |
A |
G |
G |
T |
T |
A |
3 |
- |
- |
A |
T |
T |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
G
|
A
|
T
|
T
|
C
|
G
|
C
|
A
|
C
|
C
|
C
|
A
|
G
|
G
|
G
|
C
|
G
|
C
|
T
|
C
|
T
|
G
|
A
|
G
|
A
|
T
|
C
|
G
|
G
|
A
|
G
|
C
|
A
|
-
|
C
|
-
|
C
|
G
|
G
|
G
|
C
|
T
|
C
|
2
|
G
|
T
|
G
|
G
|
G
|
T
|
C
|
A
|
C
|
-
|
2
|
3
|
C
|
A
|
T
|
T
|
C
|
G
|
C
|
C
|
-
|
T
|
T
|
T
|
A
|
A
|
C
|
T
|
G
|
T
|
C
|
G
|
-
|
A
|
C
|
C
|
G
|
C
|
A
|
T/G
|
C/G
|
T/C
|
C/T
|
T/C
|
-
|
T
|
T
|
C
|
T
|
C
|
A
|
G
|
42
|
-
|
A
|
C
|
C
|
T
|
G
|
T
|
G
|
-
|
G
|
A
|
C
|
A
|
C
|
C
|
C
|
A
|
C
|
C
|
A
|
A
|
A
|
T
|
T
|
A
|
-
|
C
|
C
|
C
|
T
|
-
|
-
|
C
|
C
|
C
|
G
|
C
|
C
|
4
|
C
|
T
|
A
|
C
|
T
|
T
|
A
|
T
|
C
|
A
|
A
|
C
|
G
|
T
|
A
|
C
|
-
|
2
|
C
|
-
|
T
|
-
|
C
|
T
|
G
|
A
|
4
|
C
|
T
|
C
|
C
|
C
|
G
|
C
|
C
|
C
|
G
|
T
|
C
|
3
|
G
|
T
|
C
|
C
|
C
|
T
|
A
|
C
|
-
|
T
|
G
|
G
|
C
|
A
|
C
|
C
|
C
|
2
|
T
|
-
|
C
|
4
|
G
|
-
|
A
|
-
|
G/T
|
T
|
A
|
A
|
A
|
C
|
C
|
T
|
A
|
-
|
G
|
T
|
C
|
C
|
T
|
C
|
T
|
T
|
C
|
T
|
C
|
G
|
C
|
A
|
C
|
4
|
-
|
C
|
A
|
G
|
C
|
A
|
G
|
T
|
G
|
T
|
T
|
C
|
G
|
G
|
-
|
G
|
G
|
C
|
T
|
G
|
C
|
A
|
12
|
C
|
T
|
C
|
T
|
-
|
C
|
G
|
G
|
A
|
A
|
A
|
C
|
T
|
C
|
A
|
G
|
T
|
A
|
T
|
C
|
A
|
C
|
G
|
G
|
-
|
T
|
C
|
A
|
T
|
G
|
A
|
A
|
G
|
A
|
A
|
A
|
-
|
2
|
A
|
T
|
A
|
T
|
C
|
T
|
T
|
C
|
G
|
C
|
C
|
T
|
T
|
A
|
G
|
-/2
|
G
|
T
|
A
|
C
|
A
|
A
|
G
|
C
|
T
|
C
|
C
|
A
|
-
|
A
|
6
|
A
|
G
|
C
|
T
|
G
|
G
|
2
|
C
|
-
|
-
|
G
|
-
|
C
|
C
|
A
|
A
|
A
|
A
|
A
|
A
|
A
|
A
|
G
|
T
|
T
|
C
|
T
|
C
|
4
|
C
|
G
|
C
|
C
|
-
|
G
|
G
|
G
|
T
|
A
|
T
|
A
|
G
|
A
|
A
|
G
|
C
|
T
|
C
|
-
|
G
|
G
|
A
|
A
|
G
|
A
|
G
|
G
|
A
|
G
|
-
|
C
|
A
|
G
|
A
|
C
|
C
|
T
|
T
|
G
|
G
|
C
|
G/A
|
A
|
G
|
-
|
G
|
T
|
-
|
C
|
A
|
C
|
C
|
C
|
A
|
C
|
G
|
C
|
T
|
G
|
G
|
G
|
C
|
G
|
A
|
A
|
C
|
C
|
T
|
-
|
T
|
T
|
C
|
C
|
C
|
|