|
.012 |
.002 |
.002 |
.001 |
.0 |
.0 |
.002 |
.0 |
.181 |
.006 |
.0 |
.001 |
.021 |
.0 |
.0 |
.0 |
-- |
-- |
-- |
-- |
-- |
-- |
.032 |
.062 |
.264 |
.004 |
.013 |
.011 |
.059 |
.005 |
.189 |
.123 |
.345 |
.244 |
.115 |
.114 |
.016 |
.025 |
.968 |
.453 |
.014 |
.001 |
.0 |
.005 |
.001 |
.321 |
.001 |
.057 |
.166 |
.001 |
.0 |
.0 |
.276 |
.143 |
.016 |
.115 |
.927 |
.001 |
.002 |
.0 |
.01 |
.007 |
.002 |
.0 |
.0 |
.0 |
.0 |
.0 |
.01 |
.024 |
.279 |
.969 |
.994 |
.016 |
.029 |
.046 |
.027 |
.001 |
.001 |
.001 |
.134 |
.005 |
.002 |
.0 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
.002 |
.005 |
.0 |
.047 |
.003 |
.007 |
.008 |
.004 |
.003 |
.02 |
.001 |
.0 |
.001 |
.001 |
.001 |
.006 |
.014 |
.201 |
.199 |
.154 |
.176 |
.006 |
.051 |
.004 |
.007 |
.001 |
.001 |
.001 |
.008 |
.01 |
.009 |
.173 |
.123 |
.375 |
.0 |
.003 |
.121 |
.002 |
.001 |
.023 |
.0 |
.146 |
.004 |
.09 |
.0 |
.774 |
.0 |
.0 |
.001 |
.001 |
.086 |
.001 |
.002 |
.066 |
.0 |
.0 |
.013 |
.01 |
.0 |
.0 |
.001 |
.003 |
.009 |
.001 |
.192 |
.838 |
.156 |
.709 |
.0 |
.053 |
.013 |
.001 |
.119 |
.239 |
.607 |
.29 |
.005 |
.0 |
.007 |
.001 |
.001 |
.032 |
.003 |
.003 |
-- |
.104 |
.055 |
.0 |
.037 |
.0 |
.305 |
.306 |
.001 |
.011 |
.002 |
.524 |
.45 |
.049 |
.998 |
.001 |
.001 |
.161 |
-- |
.002 |
.011 |
.001 |
.006 |
.001 |
.937 |
.062 |
.003 |
.997 |
-- |
.002 |
.006 |
.256 |
.0 |
.003 |
.004 |
.0 |
.004 |
.013 |
.001 |
.057 |
.033 |
.002 |
.015 |
.0 |
.011 |
.0 |
.001 |
.185 |
-- |
.006 |
.012 |
-- |
-- |
-- |
-- |
-- |
-- |
.314 |
.002 |
.06 |
.0 |
.003 |
.0 |
.005 |
.007 |
.0 |
.967 |
.32 |
.002 |
.003 |
.484 |
.085 |
.077 |
.009 |
.208 |
.003 |
.003 |
.037 |
.0 |
.011 |
.001 |
.001 |
.016 |
.009 |
.034 |
.007 |
.0 |
1.0 |
.326 |
.163 |
.007 |
.081 |
.005 |
.052 |
.087 |
.374 |
.423 |
.492 |
.481 |
.454 |
.003 |
.022 |
.064 |
.004 |
.037 |
.622 |
.0 |
.001 |
.004 |
.004 |
.065 |
.011 |
.005 |
.19 |
.005 |
.002 |
.001 |
.004 |
.0 |
.003 |
.006 |
.017 |
.004 |
.001 |
.957 |
1.0 |
.027 |
.863 |
.0 |
.416 |
.253 |
.595 |
-- |
.015 |
.0 |
.014 |
.0 |
.0 |
.021 |
.0 |
.005 |
.0 |
.001 |
.179 |
.034 |
.0 |
.004 |
.001 |
.001 |
.917 |
.893 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
.893 |
.931 |
.974 |
.976 |
.998 |
.987 |
.996 |
.138 |
.987 |
.964 |
.35 |
.341 |
.486 |
.001 |
.001 |
.07 |
.001 |
.011 |
.009 |
.007 |
.009 |
.038 |
.016 |
.187 |
-- |
.169 |
.686 |
.062 |
.003 |
.01 |
.001 |
.019 |
.0 |
.0 |
.132 |
.003 |
.013 |
.137 |
.028 |
.0 |
.009 |
.438 |
.0 |
.0 |
.001 |
.003 |
.001 |
.001 |
.0 |
.0 |
.001 |
.021 |
.088 |
-- |
-- |
.121 |
.408 |
.035 |
.029 |
.0 |
.001 |
.137 |
.002 |
.0 |
.003 |
.002 |
.003 |
.001 |
.0 |
.0 |
.003 |
.0 |
.013 |
.127 |
.001 |
.014 |
.022 |
.026 |
.007 |
.003 |
.001 |
.0 |
.047 |
.0 |
.003 |
.001 |
.0 |
.0 |
.003 |
.051 |
.0 |
.0 |
.778 |
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
|
Stxbp4
|
Stxbp4
|
Stxbp4
|
Stxbp4
|
Stxbp4
|
Stxbp4
|
Stxbp4
|
Stxbp4
|
Stxbp4
|
Stxbp4
|
Stxbp4
|
Stxbp4
|
Stxbp4
|
Stxbp4
|
Stxbp4
|
Stxbp4
|
Stxbp4
|
Stxbp4
|
Stxbp4
|
Stxbp4
|
Stxbp4
|
Stxbp4
|
Stxbp4
|
Stxbp4
|
Stxbp4
|
Stxbp4
|
Stxbp4
|
Stxbp4
|
Stxbp4
|
Stxbp4
|
Stxbp4
|
Stxbp4
|
Stxbp4
|
Stxbp4
|
Stxbp4
|
Stxbp4
|
Stxbp4
|
Stxbp4
|
Stxbp4
|
Stxbp4
|
Stxbp4
|
Stxbp4
|
Stxbp4
|
|
T |
A |
T |
A |
A |
A |
T |
A |
G |
C |
T |
C |
C |
G |
C |
C |
T |
G |
G |
A |
G |
A |
C |
C |
A |
T |
C |
C |
- |
C |
T |
C |
G |
G |
G |
T |
A |
G |
7 |
A |
G |
4 |
C |
C |
G |
C |
G |
C |
- |
C |
C |
A |
C |
G |
C |
3 |
A |
G |
T |
T |
A |
C |
T |
C |
A |
C |
C |
T |
C |
G |
G |
T |
C |
A |
T |
T |
T |
T |
A |
T |
C |
C |
C |
C |
C |
C |
C |
A |
G |
C |
T |
- |
C |
C |
T |
C |
A |
- |
G |
G |
2 |
G |
- |
- |
- |
- |
- |
- |
G |
- |
- |
- |
G |
- |
5 |
- |
3 |
T |
2 |
G |
G |
- |
- |
C |
4 |
T |
C |
- |
G |
C |
- |
C |
C |
G |
C |
G |
A |
2 |
- |
T |
T |
A |
A |
G |
A |
A |
A |
G |
G |
T |
A |
C |
C |
A |
C |
A |
A |
G |
A |
C |
A |
G |
- |
C |
T |
T |
T |
T |
A |
A |
A |
- |
- |
G |
- |
T |
A |
- |
T |
C |
A |
- |
C |
T |
A |
T |
G |
T |
C |
- |
A |
A |
T |
C |
T |
A |
A |
A |
G |
A |
A |
C |
A |
G |
C |
C |
T |
C |
T |
C |
A |
G |
T |
C |
T |
C |
C |
A |
G |
- |
C |
T |
G |
T |
C |
C |
C |
T |
A |
G |
G |
C |
A |
C |
- |
T |
A |
A |
G |
T |
C |
C |
G |
G |
G |
T |
T |
G |
C |
G |
G |
4 |
- |
T |
C |
- |
T |
G |
G |
- |
T |
G |
A |
A |
A |
A |
T |
A |
C |
C |
C |
2 |
C |
A |
5 |
T |
G |
A |
T |
C |
C |
C |
A |
C |
T |
T |
C |
- |
A |
G |
C |
A |
A |
T |
T |
A |
G |
- |
C |
C |
T |
- |
- |
G |
G |
G |
C |
G |
C |
C |
2 |
C |
A |
T |
T |
G |
14 |
T |
T |
C |
C |
T |
T |
T |
G |
G |
4 |
19 |
6 |
A |
A |
A |
A |
A |
A |
A |
A |
G |
2 |
- |
G |
A |
- |
- |
T |
G |
C |
T |
T |
T |
C |
C |
A |
T |
- |
- |
A |
- |
- |
G |
C |
- |
C |
A |
T |
A |
C |
C |
T |
2 |
T |
T |
G |
A |
A |
A |
T |
T |
A |
T |
T |
T |
T |
T |
T |
3 |
A |
- |
C |
C |
3 |
T |
G |
T |
C |
T |
C |
C |
C |
A |
T |
G |
C |
A |
C |
G |
T |
T |
C |
G |
C |
C |
A |
T |
T |
C |
C |
C |
- |
T |
A |
- |
C |
G |
T |
G |
G |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
C
|
G
|
C
|
G
|
G
|
G
|
G
|
G
|
A
|
T
|
C
|
G
|
T
|
A
|
T
|
T
|
C
|
T
|
A
|
T
|
A
|
-
|
T
|
A
|
G
|
A
|
T
|
T
|
21
|
T
|
C
|
T
|
T
|
A
|
A
|
G
|
C
|
A
|
-
|
-
|
A
|
-
|
T
|
A
|
T
|
T
|
C
|
T
|
2
|
T
|
G
|
G
|
G
|
A
|
A
|
-
|
G
|
A
|
-
|
G
|
G
|
T
|
G
|
A
|
G
|
T
|
T
|
G
|
T
|
A
|
-
|
C
|
T
|
G
|
C
|
C
|
-
|
C
|
G
|
C
|
-
|
T
|
T
|
A
|
T
|
T
|
T
|
C
|
C
|
T
|
C
|
5
|
T
|
T
|
C
|
-
|
-
|
A
|
-
|
-
|
-
|
-
|
C
|
C
|
G
|
2
|
2
|
A
|
-
|
A
|
C
|
C
|
-
|
A
|
-
|
2
|
-
|
A
|
-
|
A
|
A
|
A
|
G
|
A
|
-
|
G
|
A
|
G
|
A
|
T
|
2
|
T
|
T
|
T
|
T
|
T
|
T
|
-
|
2
|
C
|
A
|
G
|
G
|
A
|
G
|
G
|
G
|
C
|
A
|
A
|
G
|
T
|
T
|
G
|
T
|
T
|
T
|
A
|
G
|
T
|
G
|
A
|
4
|
T
|
C
|
G
|
A
|
C
|
G
|
G
|
G
|
2
|
C
|
A
|
C
|
C
|
C
|
T
|
C
|
T
|
G
|
-/2
|
C/T
|
A
|
G
|
G
|
A
|
C
|
T
|
T
|
G
|
G
|
C
|
T
|
C
|
G
|
G
|
G
|
T
|
G
|
G
|
A
|
G
|
A
|
T
|
T
|
C
|
A
|
C
|
T
|
G
|
A
|
G
|
T
|
A
|
T
|
T
|
G
|
A
|
16
|
T
|
A
|
A
|
C
|
T
|
T
|
T
|
C
|
C
|
A
|
A
|
A
|
-
|
A
|
-/C
|
A
|
C
|
G
|
A
|
C
|
T
|
T
|
-
|
A
|
A
|
A
|
C
|
A
|
A
|
C
|
A
|
-
|
2
|
C
|
T
|
4
|
C
|
A
|
A
|
C
|
C
|
A
|
G
|
-
|
G
|
G
|
A
|
G
|
-
|
A
|
-
|
-
|
T
|
T
|
-
|
C
|
A
|
T
|
-
|
T
|
T
|
T
|
G
|
G
|
C
|
C
|
T
|
6
|
T
|
A
|
T
|
G
|
G
|
C
|
C
|
T
|
A
|
30
|
A
|
T
|
-
|
2
|
-/10
|
T
|
C
|
C
|
T
|
A
|
T
|
T
|
-
|
T
|
G
|
C
|
C
|
T
|
14/-
|
A
|
C
|
T
|
T
|
C
|
C
|
C
|
A
|
T
|
-
|
-
|
-
|
G
|
G
|
G
|
G
|
C
|
-
|
C
|
G
|
A
|
-
|
4
|
-
|
C
|
C
|
A
|
G
|
C
|
T
|
G
|
G
|
C
|
-
|
-
|
T
|
C
|
T
|
A
|
-
|
C
|
G
|
C
|
T
|
6
|
T
|
G
|
C
|
T
|
G
|
G
|
G
|
-
|
C
|
C
|
A
|
G
|
G
|
A/-
|
-
|
G
|
G
|
G
|
G
|
G
|
C
|
C
|
A
|
-
|
-
|
T
|
T
|
G
|
-
|
C
|
A
|
C
|
T
|
C
|
T
|
G
|
G
|
G
|
C
|
A
|
T
|
G
|
A
|
C
|
C
|
A
|
-
|
C
|
T
|
T
|
G
|
G
|
C
|
T
|
T
|
T
|
4
|
C
|
T
|
T
|
T
|
A
|
C
|
A
|
A
|
|