|
.998 |
.0 |
.001 |
.003 |
.002 |
.0 |
.0 |
.0 |
.0 |
.0 |
.001 |
.01 |
.236 |
.383 |
.0 |
.001 |
.02 |
.003 |
.0 |
.0 |
.0 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
.003 |
.017 |
.02 |
-- |
-- |
-- |
-- |
-- |
.002 |
.01 |
.079 |
.026 |
.011 |
.954 |
.017 |
.088 |
.084 |
1.0 |
.001 |
.0 |
.0 |
.001 |
.012 |
.12 |
.0 |
.0 |
.005 |
.0 |
.0 |
.001 |
.001 |
.0 |
.0 |
.0 |
.001 |
.0 |
.0 |
.0 |
.018 |
.845 |
.014 |
.002 |
.0 |
.02 |
.004 |
.0 |
.003 |
.0 |
.002 |
.001 |
.001 |
-- |
.002 |
.006 |
.001 |
.0 |
.203 |
.174 |
.231 |
.092 |
.096 |
.003 |
.0 |
.03 |
.026 |
.013 |
.019 |
.014 |
.006 |
.0 |
.002 |
.003 |
.001 |
.0 |
.0 |
.001 |
.007 |
.002 |
.002 |
.038 |
.002 |
.007 |
.007 |
.001 |
.01 |
.004 |
.324 |
.656 |
.858 |
.029 |
.002 |
.012 |
.021 |
.022 |
.045 |
.044 |
.05 |
.001 |
.003 |
.02 |
.0 |
.001 |
.007 |
.547 |
.242 |
.0 |
.004 |
.001 |
.001 |
-- |
.0 |
.0 |
.045 |
.006 |
.004 |
.001 |
.743 |
-- |
-- |
-- |
.001 |
.009 |
.031 |
.0 |
.023 |
.001 |
.0 |
.013 |
.558 |
.001 |
.0 |
.001 |
.005 |
.0 |
.001 |
.002 |
.0 |
.007 |
.005 |
.0 |
.701 |
1.0 |
.997 |
.002 |
.0 |
.015 |
.009 |
.002 |
.153 |
.089 |
.0 |
.0 |
.001 |
.007 |
.009 |
.004 |
.002 |
.004 |
.011 |
.07 |
.014 |
.009 |
.018 |
.101 |
.008 |
.0 |
.0 |
.034 |
.103 |
.013 |
.03 |
.082 |
.016 |
.002 |
.024 |
.002 |
.002 |
.002 |
.384 |
.067 |
.001 |
.0 |
.001 |
.009 |
.001 |
1.0 |
.0 |
.0 |
.0 |
.7 |
.0 |
.005 |
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
|
Ptpn5
|
Ptpn5
|
Ptpn5
|
Ptpn5
|
Ptpn5
|
Ptpn5
|
Ptpn5
|
Ptpn5
|
Ptpn5
|
Ptpn5
|
Ptpn5
|
Ptpn5
|
Ptpn5
|
Ptpn5
|
Ptpn5
|
Ptpn5
|
Ptpn5
|
Ptpn5
|
Ptpn5
|
Ptpn5
|
Ptpn5
|
Ptpn5
|
|
C |
C |
C |
G |
A |
C |
T |
G |
G |
A |
A |
G |
C |
C |
A |
G |
G |
G |
C |
C |
C |
- |
- |
G |
A |
2 |
- |
- |
A |
- |
- |
- |
G |
T |
T |
C |
G |
6 |
G |
8 |
G |
G |
C |
G |
G |
G |
C |
A |
T |
G |
C |
G |
C |
- |
C |
A |
C |
C |
T |
T |
A |
T |
C |
C |
C |
T |
C |
C |
T |
T |
C |
45 |
A |
G |
G |
A |
C |
G |
T |
T |
C |
- |
A |
3 |
A |
- |
- |
- |
- |
- |
G |
T |
A |
A |
G |
T |
G |
4 |
- |
- |
C |
G |
G |
A |
- |
- |
G |
A |
T |
C |
2 |
C |
2 |
- |
- |
- |
C |
G |
3 |
- |
- |
G |
C |
T |
A |
- |
G |
G |
G |
- |
G |
T |
2 |
- |
- |
- |
T |
A |
G |
G |
T |
A |
G |
A |
A |
A |
G |
- |
A |
T |
G |
G |
T |
T |
A |
C |
A |
T |
T |
G |
C |
T |
A |
G |
G |
G |
G |
T |
A |
G |
C |
G |
T |
6 |
- |
T |
C |
G |
T |
A |
T |
T |
C |
G |
2 |
8 |
T |
C |
2 |
C |
C |
G |
C |
A |
C |
2 |
4 |
C |
A |
- |
C |
T |
C |
4 |
T |
T |
C |
C |
G |
G |
C |
G |
T |
C |
G |
G |
C |
C |
T |
A |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
A
|
T
|
T
|
T
|
G
|
T
|
A
|
C/7
|
A
|
G
|
G
|
A
|
T
|
A
|
C
|
A
|
C
|
A
|
T
|
T
|
T
|
A
|
C
|
-
|
-
|
-
|
T
|
A
|
G
|
A
|
G
|
T
|
T
|
-
|
G
|
-
|
T
|
-
|
-
|
-
|
T
|
A
|
T
|
A
|
A
|
A
|
T
|
G
|
C
|
A
|
T
|
T
|
T
|
18
|
T
|
G
|
T
|
T
|
G
|
C
|
G
|
C
|
T
|
T
|
A
|
C
|
T
|
A
|
C
|
C
|
A
|
-
|
-
|
A
|
A
|
G
|
T
|
A
|
G
|
C
|
T
|
2
|
-
|
-
|
-
|
C
|
G
|
T
|
C
|
C
|
-
|
-
|
-
|
-
|
A
|
-
|
-
|
-
|
T
|
G
|
A
|
-
|
T
|
G
|
A
|
2
|
-
|
-
|
-
|
-
|
-
|
T
|
-
|
A
|
A
|
C
|
-
|
-
|
-
|
C
|
C
|
A
|
-
|
-
|
-
|
T
|
-
|
-
|
T
|
C
|
-
|
-
|
-
|
2
|
G
|
G
|
C
|
G
|
T
|
A
|
-
|
G
|
T
|
C
|
G
|
A/G
|
A
|
A
|
-
|
C
|
A
|
A
|
-
|
C
|
G
|
T
|
G
|
C
|
C
|
T
|
T
|
C
|
G
|
A
|
T
|
A
|
A
|
C
|
-
|
A
|
T
|
A
|
C
|
-
|
G
|
C
|
T
|
A
|
A
|
C
|
C
|
C
|
T
|
A
|
-
|
-
|
G
|
C/G
|
2/-
|
C/G
|
C/G
|
A
|
G
|
G
|
G
|
-
|
-
|
T
|
G
|
2
|
G
|
C
|
T
|
-
|
C
|
C
|
T
|
T
|
A
|
T
|
T
|
A
|
C
|
T
|
T
|
A
|
T
|
T
|
C
|
T
|
|