|
.718 |
.0 |
.0 |
.006 |
.003 |
.001 |
.007 |
.127 |
.0 |
.0 |
.0 |
.002 |
.0 |
.002 |
.002 |
.007 |
.001 |
.54 |
.001 |
.0 |
.004 |
.0 |
.002 |
.018 |
.017 |
.013 |
.0 |
.0 |
.067 |
.0 |
.008 |
.02 |
-- |
.001 |
.007 |
.019 |
.003 |
.001 |
.001 |
.013 |
.001 |
.057 |
.008 |
.002 |
-- |
.082 |
.0 |
.0 |
.001 |
.001 |
.022 |
.002 |
.004 |
.002 |
.039 |
.035 |
.042 |
.009 |
.006 |
.04 |
.005 |
.001 |
.046 |
.046 |
.077 |
.003 |
.153 |
.004 |
.009 |
.048 |
.035 |
.0 |
.012 |
.0 |
.048 |
.066 |
.002 |
.698 |
.0 |
.002 |
.006 |
1.0 |
.002 |
.02 |
.003 |
.01 |
.064 |
.068 |
.073 |
.007 |
.17 |
.075 |
.002 |
.0 |
.027 |
-- |
-- |
.007 |
.001 |
.031 |
.132 |
.003 |
-- |
.037 |
.014 |
.004 |
.12 |
.035 |
.005 |
.001 |
.001 |
.001 |
.0 |
.282 |
.251 |
.001 |
.007 |
.001 |
.0 |
.0 |
.001 |
.0 |
.003 |
.002 |
.007 |
.008 |
.003 |
.03 |
.025 |
.001 |
.037 |
.009 |
.004 |
.009 |
.001 |
.002 |
.001 |
.002 |
.001 |
.04 |
.103 |
.004 |
.0 |
.003 |
.619 |
.783 |
.001 |
.001 |
.001 |
.0 |
.001 |
.0 |
.01 |
.305 |
.0 |
.647 |
.634 |
.01 |
.04 |
.096 |
.039 |
.004 |
.009 |
.041 |
.011 |
.015 |
.002 |
.002 |
.001 |
.005 |
.003 |
.006 |
.0 |
.0 |
.0 |
.115 |
.0 |
.0 |
.621 |
.589 |
.002 |
.0 |
.005 |
.229 |
.007 |
.006 |
.011 |
.024 |
.003 |
.005 |
.001 |
.085 |
.0 |
.0 |
.001 |
.056 |
.019 |
.034 |
.012 |
.002 |
.004 |
.0 |
.001 |
.802 |
.007 |
.063 |
.113 |
.177 |
.825 |
.012 |
.0 |
.028 |
.006 |
.001 |
.006 |
.069 |
.0 |
.0 |
.001 |
.01 |
-- |
.027 |
.748 |
.147 |
.003 |
.0 |
.001 |
.031 |
.002 |
.001 |
.012 |
.002 |
.001 |
.0 |
.005 |
.035 |
.001 |
.0 |
.845 |
.248 |
.028 |
1.0 |
.003 |
.004 |
.0 |
.077 |
.038 |
.0 |
.012 |
.003 |
.007 |
.0 |
.003 |
.0 |
.0 |
.0 |
.0 |
.0 |
.015 |
.0 |
.001 |
.0 |
.005 |
.002 |
.811 |
.089 |
.03 |
.285 |
.108 |
.005 |
.024 |
.01 |
.029 |
.037 |
.105 |
.0 |
.056 |
.023 |
.019 |
.0 |
.655 |
.001 |
.003 |
.088 |
.003 |
.007 |
.007 |
-- |
.007 |
.023 |
.0 |
.001 |
.0 |
.001 |
.011 |
.007 |
.003 |
.028 |
.001 |
.002 |
.0 |
.012 |
.066 |
.255 |
.013 |
.001 |
.002 |
.0 |
.012 |
.047 |
-- |
-- |
.0 |
.016 |
.0 |
.0 |
.002 |
.001 |
.018 |
.011 |
.195 |
.992 |
.0 |
.078 |
.0 |
.013 |
.0 |
.0 |
.001 |
.033 |
.003 |
.001 |
.0 |
.0 |
.007 |
.06 |
.017 |
.053 |
.006 |
.031 |
.002 |
.002 |
.004 |
.008 |
.006 |
.008 |
.001 |
.001 |
.004 |
.005 |
.017 |
.697 |
-- |
.065 |
.033 |
.05 |
.021 |
.054 |
.081 |
.013 |
.211 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
.068 |
.654 |
.179 |
.048 |
.017 |
.018 |
.037 |
.262 |
.252 |
.08 |
.045 |
.018 |
.025 |
.142 |
.103 |
.0 |
.002 |
.0 |
.998 |
.006 |
.001 |
.006 |
.063 |
.001 |
.013 |
.023 |
.031 |
.004 |
.07 |
.0 |
.0 |
.0 |
.01 |
.002 |
.001 |
.01 |
.003 |
.001 |
.011 |
.004 |
.008 |
.101 |
.006 |
.003 |
.002 |
.983 |
.013 |
.946 |
.008 |
.001 |
.008 |
.013 |
-- |
.011 |
.043 |
.038 |
.015 |
.0 |
.0 |
.0 |
.001 |
.0 |
.005 |
.0 |
.0 |
.001 |
.001 |
.002 |
.0 |
.0 |
.007 |
.044 |
.005 |
.04 |
.0 |
.003 |
.001 |
.019 |
.0 |
.109 |
.063 |
.0 |
.034 |
.97 |
.902 |
.005 |
.016 |
.004 |
.001 |
.001 |
.0 |
.005 |
.0 |
.0 |
.001 |
.0 |
.0 |
.024 |
.073 |
.0 |
.002 |
.0 |
.002 |
.0 |
.0 |
.0 |
.0 |
.0 |
.0 |
.001 |
.0 |
.072 |
.011 |
.012 |
.018 |
.0 |
.003 |
.07 |
.032 |
.683 |
.044 |
.095 |
.003 |
-- |
-- |
.008 |
.002 |
.006 |
.003 |
.011 |
.001 |
.003 |
.002 |
.002 |
.173 |
-- |
.207 |
.002 |
.939 |
.005 |
.106 |
.004 |
.087 |
.549 |
.003 |
.005 |
.001 |
.065 |
.027 |
.011 |
.003 |
-- |
-- |
-- |
.005 |
.097 |
.001 |
.007 |
.0 |
.001 |
.005 |
.024 |
.0 |
.019 |
.001 |
.003 |
.075 |
.009 |
.003 |
.011 |
.012 |
.007 |
-- |
-- |
-- |
-- |
.003 |
.002 |
.001 |
.003 |
.001 |
.002 |
.06 |
.0 |
.003 |
.688 |
.001 |
.003 |
.049 |
.087 |
-- |
-- |
-- |
.0 |
.007 |
.001 |
.054 |
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
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|
--
|
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|
--
|
--
|
--
|
--
|
--
|
--
|
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|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
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--
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--
|
--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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|
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|
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|
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|
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|
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|
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|
--
|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
--
|
--
|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
--
|
--
|
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|
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|
--
|
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|
--
|
--
|
--
|
--
|
--
|
--
|
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|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
|
Ptpn13
|
Ptpn13
|
Ptpn13
|
Ptpn13
|
Ptpn13
|
Ptpn13
|
Ptpn13
|
Ptpn13
|
Ptpn13
|
Ptpn13
|
Ptpn13
|
Ptpn13
|
Ptpn13
|
Ptpn13
|
Ptpn13
|
Ptpn13
|
Ptpn13
|
Ptpn13
|
Ptpn13
|
Ptpn13
|
Ptpn13
|
Ptpn13
|
Ptpn13
|
Ptpn13
|
Ptpn13
|
Ptpn13
|
Ptpn13
|
Ptpn13
|
Ptpn13
|
Ptpn13
|
Ptpn13
|
Ptpn13
|
Ptpn13
|
Ptpn13
|
Ptpn13
|
Ptpn13
|
Ptpn13
|
Ptpn13
|
Ptpn13
|
Ptpn13
|
Ptpn13
|
Ptpn13
|
Ptpn13
|
Ptpn13
|
Ptpn13
|
Ptpn13
|
Ptpn13
|
Ptpn13
|
Ptpn13
|
Ptpn13
|
Ptpn13
|
Ptpn13
|
Ptpn13
|
Ptpn13
|
Ptpn13
|
Ptpn13
|
Ptpn13
|
|
T |
A |
G |
C |
G |
G |
T |
G |
A |
T |
7 |
A |
C |
A |
C |
A |
C |
A |
G |
C |
23 |
T |
T |
- |
G |
T |
- |
C |
G |
G |
G |
C |
C |
T |
A |
- |
3 |
A |
G |
C |
C |
G |
A |
12 |
5 |
- |
A |
T |
A |
- |
C |
A |
A |
A |
- |
- |
C |
C |
- |
A |
A |
C |
- |
2 |
A |
C |
31 |
G |
- |
T |
G |
G |
C |
T |
- |
- |
T |
G |
G |
G |
T |
T |
G |
T |
T |
A |
T |
A |
T |
G |
T |
A |
T |
T |
A |
10 |
6 |
A |
C |
T |
C |
21 |
72 |
G |
G |
G |
A |
4 |
G |
- |
G |
A |
- |
A |
A |
T |
G |
A |
A |
C |
A |
2 |
G |
A |
- |
G |
C |
C |
C |
C |
G |
A |
G |
G |
G |
C |
T |
A |
G |
T |
T |
T |
A |
14 |
C |
5 |
C |
G |
A |
A |
T |
- |
A |
G |
T |
C |
A |
- |
G |
C |
G |
G |
T |
18 |
33 |
T |
9 |
A |
A |
A |
A |
G |
G |
A |
G |
A |
A |
- |
G |
T |
T |
C |
G |
- |
G |
A |
- |
- |
G |
- |
T |
T |
A |
G |
T |
- |
T |
G |
G |
A |
C |
C |
G |
G |
A |
T |
T |
3 |
C |
G |
G |
G |
G |
T |
A |
C |
A |
G |
C |
C |
A |
C |
C |
A |
A |
A |
T |
T |
T |
C |
T |
T |
G |
G |
G |
3 |
2 |
G |
A |
- |
C |
G |
C |
A |
C |
G |
C |
- |
T |
G |
- |
C |
C |
A |
A |
G |
A |
G |
- |
A |
G |
C |
G |
C |
A |
C |
T |
A |
- |
A |
A |
G |
C |
G |
T |
A |
- |
C |
T |
C |
G |
G |
T |
T |
- |
A |
C |
T |
T |
T |
C |
C |
G |
6 |
T |
G |
C |
T |
G |
T |
T |
A |
G |
T |
C |
- |
A |
T |
G |
4 |
G |
A |
T |
- |
T |
G |
2 |
A |
T |
A |
G |
A |
T |
12 |
A |
G |
C |
C |
A |
C |
- |
- |
A |
G |
A |
A |
A |
- |
G |
2 |
A |
G |
G |
- |
G |
A |
A |
C |
A |
29 |
G |
A |
G |
T |
C |
T |
A |
A |
A |
C |
A |
T |
G |
T |
T |
T |
T |
T |
T |
A |
T |
C |
C |
A |
C |
C |
C |
G |
T |
C |
T |
A |
G |
A |
C |
- |
C |
A |
T |
T |
A |
T |
- |
A |
A |
83 |
G |
- |
T |
A |
G |
C |
C |
G |
C |
A |
A |
A |
A |
G |
A |
A |
A |
A |
A |
T |
G |
C |
A |
A |
T |
A |
- |
A |
G |
A |
A |
G |
T |
G |
T |
T |
T |
T |
T |
A |
A |
T |
A |
G |
G |
G |
A |
G |
A |
C |
- |
C |
G |
C |
C |
G |
C |
T |
G |
G |
T |
A |
A |
A |
G |
C |
T |
C |
A |
T |
G |
5 |
A |
C |
A |
T |
G |
T |
C |
T |
- |
G |
G |
A |
T |
T |
G |
A |
A |
A |
A |
4 |
C |
G |
T |
- |
G |
G |
A |
C |
- |
C |
T |
C |
G |
T |
G |
A |
G |
A |
A |
C |
- |
- |
C |
G |
C |
C |
A |
2 |
A |
A |
A |
A |
G |
G |
A |
G |
C |
T |
- |
- |
9 |
C |
- |
G |
G |
T |
G |
3 |
G |
T |
C |
- |
C |
- |
A |
- |
C |
C |
- |
32 |
C |
C |
G |
9 |
G |
11 |
3 |
G |
T |
T |
T |
T |
T |
T |
T |
C |
C |
A |
T |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
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|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
C
|
G
|
T
|
T
|
C
|
A
|
C
|
A
|
G
|
-
|
-
|
G
|
T
|
T
|
T
|
T
|
T
|
C/T
|
T
|
T
|
-
|
C
|
G
|
16
|
A
|
C
|
28
|
G
|
A
|
A
|
A
|
T
|
T
|
C
|
T
|
3
|
-
|
T
|
A
|
T
|
T
|
T
|
T
|
-
|
-
|
5
|
G
|
A
|
G
|
C
|
T
|
-
|
G
|
-
|
4
|
G
|
T
|
T
|
T
|
C
|
C
|
T
|
2
|
-
|
G
|
T
|
-
|
A
|
4
|
C
|
A
|
C
|
G
|
C
|
C
|
3
|
C
|
A
|
A
|
A
|
C
|
G
|
T
|
C
|
C
|
G
|
G
|
T
|
C
|
A
|
C
|
G
|
C
|
C
|
G
|
-
|
-
|
G
|
T
|
C
|
T
|
-
|
-
|
T
|
-
|
-
|
T
|
-
|
A
|
T
|
A
|
G
|
20
|
C
|
G
|
C
|
C
|
G
|
G
|
T
|
G
|
-
|
T
|
G
|
G
|
A
|
T
|
T
|
A
|
-
|
C
|
G
|
A
|
A
|
A
|
T
|
C
|
G
|
T
|
A
|
-
|
A
|
G
|
-
|
T
|
-
|
T
|
A
|
G
|
T
|
G
|
7
|
G
|
A
|
C
|
T
|
G
|
A
|
T
|
T
|
A
|
A
|
C
|
-
|
-
|
C
|
-
|
G
|
G
|
G
|
G
|
A
|
A
|
T
|
A
|
G
|
G
|
A
|
T
|
C
|
G
|
G
|
A
|
4
|
A
|
G
|
T
|
4
|
A
|
2
|
C
|
C
|
C
|
A
|
C
|
-/T
|
A
|
A
|
A
|
G
|
T
|
T
|
A
|
T
|
T
|
A
|
A
|
-
|
T
|
A
|
A
|
A
|
C
|
C
|
G
|
T
|
C
|
A
|
T
|
T
|
G
|
T
|
-
|
G
|
G
|
G
|
A
|
C
|
C
|
T
|
G
|
C
|
C
|
T
|
A
|
-
|
-
|
A
|
C
|
4
|
T
|
A
|
T
|
T
|
G
|
A
|
-
|
3
|
A
|
A
|
G
|
A
|
T
|
C
|
C
|
A
|
G
|
-
|
4
|
G
|
A
|
G
|
A
|
T
|
G
|
T
|
C
|
T
|
G
|
C
|
T
|
T
|
A
|
T
|
C
|
C
|
7
|
T
|
C
|
G
|
A
|
C
|
C
|
G
|
C
|
G
|
T
|
C
|
C
|
C
|
T
|
T
|
C
|
-
|
C
|
A
|
T
|
C
|
A
|
C
|
G
|
C
|
C
|
A
|
A
|
45
|
C
|
C
|
A
|
-
|
-
|
G
|
C
|
C
|
G
|
A
|
-
|
C
|
C
|
G
|
A
|
G
|
C
|
-
|
T
|
A
|
T
|
A
|
G
|
T
|
5
|
23
|
G
|
T
|
G
|
G
|
T
|
2
|
T
|
-
|
C
|
A
|
A
|
4
|
A
|
G
|
G
|
G
|
G
|
-
|
A
|
G
|
T
|
C
|
T
|
C
|
C
|
T
|
C
|
A
|
C
|
C
|
A
|
C
|
G
|
G
|
C
|
A
|
C
|
C
|
G
|
T
|
T
|
G
|
A
|
A
|
T
|
A
|
G
|
T
|
A
|
G
|
A
|
G
|
T
|
2
|
T
|
G
|
C
|
C
|
G
|
C
|
2
|
G
|
G
|
-
|
A
|
C/G
|
G
|
G
|
A
|
A
|
T
|
C
|
T
|
G
|
G
|
G
|
C
|
T
|
G
|
G
|
-
|
T
|
G
|
G
|
A
|
T
|
G
|
C
|
A
|
G
|
A
|
T
|
C
|
G
|
G
|
C
|
C
|
A
|
-
|
C
|
C
|
C
|
A
|
G
|
C
|
C
|
C
|
A
|
C
|
A
|
G
|
A
|
G
|
T
|
A
|
T
|
A
|
T
|
A
|
A
|
T
|
G
|
C
|
T
|
-
|
T
|
G
|
G
|
A
|
T
|
G
|
G
|
C
|
C
|
T
|
-
|
G
|
T
|
-
|
C
|
A
|
C
|
T
|
C
|
9
|
A
|
A
|
G
|
C
|
C
|
A
|
G
|
G
|
G
|
G
|
-
|
T
|
A
|
A
|
2
|
A
|
A
|
-
|
T
|
C
|
T
|
C
|
T
|
A
|
C
|
A
|
G
|
A
|
G
|
-
|
A
|
2
|
T
|
G
|
A
|
T
|
T
|
C
|
-
|
T
|
G
|
G
|
-
|
C
|
A
|
G
|
A
|
A
|
C
|
4
|
A
|
-
|
A
|
2
|
A
|
A
|
G
|
A
|
-
|
T
|
G
|
T
|
G
|
T
|
12
|
G
|
G
|
A
|
G
|
A
|
-
|
A
|
A
|
A
|
-
|
A
|
-
|
-
|
-
|
-
|
-
|
-
|
-
|
-
|
-
|
-
|
T
|
G
|
G
|
C
|
|