|
.003 |
.01 |
.0 |
.001 |
.018 |
.023 |
.214 |
.935 |
.0 |
.001 |
.001 |
-- |
.031 |
.557 |
.005 |
.051 |
.007 |
.288 |
.003 |
.014 |
.0 |
.302 |
.001 |
.027 |
-- |
-- |
-- |
.002 |
.001 |
.0 |
.0 |
.001 |
.005 |
.0 |
.036 |
.006 |
.15 |
.002 |
.0 |
.004 |
.001 |
.003 |
.0 |
.025 |
.001 |
.006 |
.008 |
.0 |
.39 |
.0 |
.002 |
.002 |
.008 |
.035 |
.005 |
.001 |
.013 |
.207 |
.001 |
.007 |
.0 |
.001 |
.002 |
.002 |
.001 |
.002 |
.0 |
.013 |
.005 |
.007 |
.008 |
.001 |
.045 |
.157 |
.003 |
.001 |
.006 |
.018 |
.003 |
.0 |
.001 |
.001 |
.024 |
.01 |
.007 |
.001 |
.899 |
.957 |
.323 |
.015 |
.007 |
.007 |
.003 |
.483 |
.0 |
.197 |
.001 |
.008 |
.014 |
.026 |
.603 |
.014 |
.05 |
.009 |
.0 |
.0 |
.046 |
.0 |
.159 |
.317 |
.13 |
.356 |
.166 |
.077 |
.837 |
.756 |
.003 |
.009 |
.038 |
.06 |
-- |
-- |
-- |
.007 |
.271 |
.003 |
.597 |
.966 |
.96 |
.963 |
.003 |
.365 |
.017 |
.219 |
.257 |
-- |
.021 |
.021 |
.004 |
.152 |
.094 |
.028 |
.127 |
.003 |
.117 |
.006 |
.221 |
.0 |
.008 |
.098 |
.234 |
.067 |
.037 |
.088 |
.004 |
.173 |
.001 |
.007 |
.754 |
.002 |
.041 |
.001 |
.012 |
.015 |
.041 |
.02 |
.166 |
.003 |
.0 |
.0 |
.016 |
.029 |
.345 |
.168 |
.002 |
.023 |
.008 |
.005 |
.001 |
.002 |
.133 |
.048 |
.001 |
.002 |
.049 |
.001 |
.999 |
.004 |
.002 |
.006 |
.0 |
-- |
-- |
.005 |
.001 |
.006 |
.002 |
.023 |
.118 |
.244 |
.017 |
.0 |
.994 |
.004 |
.0 |
.0 |
.003 |
.01 |
.001 |
.01 |
.001 |
.004 |
.001 |
.031 |
.014 |
.008 |
.002 |
-- |
.007 |
.041 |
.014 |
.0 |
.277 |
.214 |
.029 |
.001 |
.751 |
.713 |
.936 |
.052 |
.008 |
.18 |
.07 |
.999 |
-- |
-- |
.207 |
.037 |
.112 |
.003 |
.086 |
.982 |
.016 |
.037 |
.037 |
.174 |
.0 |
.008 |
.041 |
.0 |
.002 |
.001 |
.03 |
.006 |
.0 |
.001 |
.706 |
.002 |
.011 |
.0 |
.002 |
.001 |
.0 |
.003 |
.0 |
.0 |
.533 |
.995 |
.913 |
1.0 |
.003 |
.084 |
.0 |
.115 |
.036 |
.37 |
.103 |
.015 |
.003 |
.005 |
.009 |
.0 |
.347 |
.001 |
.001 |
.002 |
.095 |
.002 |
.052 |
.018 |
.004 |
.762 |
.048 |
.027 |
.002 |
.001 |
.001 |
.0 |
.0 |
.0 |
.996 |
1.0 |
.001 |
.091 |
.015 |
.0 |
.153 |
.021 |
.002 |
.0 |
.0 |
.001 |
.0 |
|
Prkar1b
|
Prkar1b
|
Prkar1b
|
Prkar1b
|
Prkar1b
|
Prkar1b
|
Prkar1b
|
Prkar1b
|
Prkar1b
|
Prkar1b
|
Prkar1b
|
Prkar1b
|
Prkar1b
|
Prkar1b
|
Prkar1b
|
Prkar1b
|
Prkar1b
|
Prkar1b
|
Prkar1b
|
Prkar1b
|
Prkar1b
|
Prkar1b
|
Prkar1b
|
Prkar1b
|
Prkar1b
|
Prkar1b
|
Prkar1b
|
Prkar1b
|
Prkar1b
|
Prkar1b
|
Prkar1b
|
Prkar1b
|
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
|
A |
G |
C |
A |
G |
T |
G |
A |
G |
G |
C |
A |
T |
A |
T |
C |
A |
A |
T |
C |
G |
C |
C |
A |
G |
C |
T |
C |
T |
A |
C |
T |
C |
G |
C |
C |
G |
C |
T |
C |
T |
A |
T |
C |
T |
T |
C |
C |
A |
G |
G |
T |
G |
G |
A |
C |
A |
A |
G |
G |
A |
C |
G |
A |
A |
G |
G |
T |
G |
A |
T |
G |
C |
T |
T |
G |
G |
T |
T |
C |
T |
C |
G |
G |
T |
T |
G |
G |
G |
T |
C |
G |
G |
C |
A |
G |
G |
A |
G |
T |
C |
G |
C |
A |
A |
T |
G |
T |
C |
A |
T |
G |
G |
G |
G |
A |
A |
T |
C |
G |
C |
T |
A |
G |
A |
T |
C |
T |
C |
G |
T |
A |
T |
T |
C |
C |
T |
C |
C |
T |
T |
C |
G |
T |
A |
G |
T |
G |
T |
T |
A |
G |
C |
T |
A |
A |
A |
C |
G |
A |
G |
T |
T |
G |
G |
T |
C |
T |
A |
C |
G |
A |
C |
G |
T |
T |
A |
G |
C |
T |
G |
T |
A |
A |
T |
C |
C |
T |
T |
C |
T |
C |
C |
C |
A |
C |
C |
C |
G |
A |
A |
T |
T |
A |
T |
T |
G |
C |
A |
A |
G |
T |
A |
G |
T |
G |
A |
G |
C |
T |
A |
G |
G |
C |
G |
C |
A |
A |
A |
G |
T |
C |
T |
C |
T |
C |
G |
G |
A |
A |
A |
A |
G |
A |
C |
C |
T |
C |
C |
G |
G |
A |
G |
C |
C |
T |
C |
C |
G |
T |
A |
G |
G |
T |
T |
G |
C |
A |
T |
G |
G |
G |
A |
A |
T |
G |
T |
A |
C |
A |
A |
A |
T |
G |
G |
G |
G |
G |
T |
T |
C |
T |
C |
A |
T |
C |
G |
C |
C |
A |
T |
G |
A |
G |
T |
C |
C |
T |
C |
A |
A |
A |
A |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
G
|
A
|
T
|
G
|
A
|
C
|
T
|
G
|
A
|
A
|
C/T
|
G
|
T/C
|
G
|
C
|
T
|
G
|
G
|
A
|
T
|
A
|
T
|
C/T
|
A/C
|
A
|
T
|
C
|
T
|
C
|
A/C
|
C/A
|
C
|
T
|
A
|
T
|
T
|
A
|
C/G
|
G
|
T
|
C
|
C
|
C
|
T
|
C
|
C
|
T
|
T
|
G
|
G/T
|
A
|
C
|
A
|
A
|
G
|
T
|
C
|
G
|
A
|
T
|
G
|
T
|
A
|
C
|
G
|
A
|
A
|
T/C
|
A
|
G
|
G
|
A
|
T
|
C
|
C
|
A
|
A
|
C
|
C
|
T
|
A
|
T
|
A
|
A
|
C
|
C
|
G/T
|
G/T
|
A
|
G
|
T
|
C
|
C
|
T
|
C
|
A
|
T
|
G
|
A
|
C
|
T
|
A
|
T
|
G
|
G
|
A
|
A
|
C
|
T
|
C
|
C
|
A
|
C
|
A
|
G/A
|
C
|
G
|
C
|
T
|
A
|
A
|
T/C
|
G
|
A
|
G
|
G
|
C/T
|
C
|
T
|
A
|
C
|
G
|
C
|
A
|
T
|
C/T
|
C
|
T
|
A
|
C
|
C
|
T
|
A
|
C
|
G
|
A
|
C
|
T
|
C
|
C
|
G
|
T
|
T
|
C
|
G
|
G
|
G
|
T
|
A
|
G
|
A
|
C
|
C
|
A
|
A
|
C
|
G
|
C
|
G
|
T
|
C
|
G
|
T
|
A
|
C
|
C
|
T
|
A
|
T
|
G
|
A
|
C
|
G
|
G
|
G
|
T
|
T
|
G
|
G
|
T
|
A
|
C/T
|
C/T
|
T
|
C
|
T
|
G
|
A
|
A
|
G
|
G
|
G
|
C
|
G
|
C
|
C
|
A
|
T
|
C
|
G
|
C
|
C
|
G
|
T
|
C
|
A
|
G
|
T
|
A
|
T/C
|
G
|
A
|
C
|
T
|
A
|
T
|
A/G
|
A/C
|
G
|
A
|
C
|
A
|
G
|
C/G
|
T/C
|
C/T
|
G/A
|
G/A
|
C
|
C
|
T
|
C
|
A
|
G
|
A
|
G
|
C
|
T
|
T
|
C
|
T
|
T
|
A
|
T
|
G
|
G
|
A
|
T
|
A
|
C
|
G
|
A
|
A
|
C
|
C
|
A
|
C/T
|
A/G
|
T/G
|
T
|
A
|
C
|
G
|
G
|
C
|
A
|
C
|
G
|
T
|
G
|
G
|
G
|
C
|
A
|
A
|
A
|
C
|
A
|
C
|
C
|
T
|
C
|
G
|
G
|
C
|
T
|
A
|
T
|
T
|
G
|
C
|
A
|
G
|
A
|
A
|
T
|
T
|
C
|
T
|
G
|
C
|
G
|
T
|
|