|
.0 |
.001 |
.001 |
.015 |
.0 |
.0 |
.003 |
.0 |
.0 |
.0 |
.0 |
.001 |
.094 |
.0 |
.001 |
.004 |
.005 |
.0 |
.02 |
.003 |
.042 |
.133 |
.039 |
.274 |
.0 |
.0 |
.002 |
.008 |
-- |
-- |
.014 |
.0 |
.0 |
.949 |
.0 |
.977 |
.184 |
.0 |
.005 |
.009 |
.006 |
.022 |
.0 |
.0 |
.585 |
.968 |
.0 |
.0 |
.024 |
.01 |
.003 |
.007 |
.001 |
.001 |
.001 |
.0 |
.0 |
.005 |
.015 |
.007 |
.0 |
.001 |
.992 |
.0 |
.0 |
.008 |
.002 |
.07 |
.436 |
.012 |
.0 |
-- |
.0 |
.053 |
.206 |
.71 |
.082 |
.001 |
.171 |
.0 |
.0 |
.073 |
.021 |
.001 |
.001 |
.0 |
.0 |
.008 |
.005 |
.0 |
.0 |
.0 |
.0 |
.0 |
.001 |
.001 |
.014 |
.005 |
.004 |
.001 |
.308 |
.002 |
.0 |
.012 |
.001 |
.005 |
.016 |
.015 |
.001 |
.0 |
.052 |
.004 |
.033 |
.001 |
.003 |
.002 |
.012 |
.001 |
.004 |
.572 |
.148 |
.001 |
.0 |
.006 |
.0 |
.0 |
.389 |
.553 |
.0 |
.0 |
.006 |
.017 |
.992 |
.0 |
.01 |
.268 |
.467 |
.001 |
.001 |
.0 |
.0 |
.0 |
.843 |
.0 |
.001 |
.0 |
.0 |
.0 |
.0 |
.0 |
.0 |
.0 |
.0 |
.0 |
.001 |
.001 |
.005 |
.22 |
.0 |
.029 |
.021 |
.03 |
.0 |
.001 |
.44 |
.105 |
.003 |
.15 |
.018 |
.003 |
.001 |
.01 |
.004 |
.005 |
.006 |
.017 |
.0 |
.014 |
.0 |
.002 |
.0 |
.0 |
.0 |
.004 |
.001 |
.006 |
.0 |
.0 |
.0 |
.002 |
.005 |
.003 |
.129 |
.656 |
.022 |
.714 |
.008 |
.106 |
.524 |
.245 |
.022 |
.007 |
.007 |
.005 |
.004 |
.0 |
.002 |
.0 |
.003 |
.033 |
.0 |
.074 |
.047 |
.042 |
.003 |
.002 |
.039 |
.297 |
.024 |
.204 |
.0 |
.058 |
.006 |
.094 |
.0 |
.0 |
.01 |
.594 |
.083 |
.002 |
.002 |
.851 |
.001 |
.003 |
.001 |
.063 |
.014 |
.012 |
.051 |
.001 |
.017 |
.016 |
.001 |
.008 |
.084 |
.008 |
.035 |
.245 |
.018 |
.002 |
.094 |
.0 |
.0 |
.0 |
.0 |
.018 |
.144 |
.037 |
.11 |
.009 |
.006 |
.003 |
.011 |
.078 |
.066 |
.004 |
.0 |
.002 |
.0 |
.001 |
.002 |
.419 |
.306 |
.0 |
.0 |
.001 |
.304 |
.001 |
.025 |
.0 |
.007 |
.012 |
.008 |
.005 |
.006 |
.005 |
.0 |
.17 |
.002 |
.0 |
.0 |
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
|
Prex1
|
Prex1
|
Prex1
|
Prex1
|
Prex1
|
Prex1
|
Prex1
|
Prex1
|
Prex1
|
Prex1
|
Prex1
|
Prex1
|
Prex1
|
Prex1
|
Prex1
|
Prex1
|
Prex1
|
Prex1
|
Prex1
|
Prex1
|
Prex1
|
Prex1
|
Prex1
|
Prex1
|
Prex1
|
Prex1
|
Prex1
|
Prex1
|
Prex1
|
Prex1
|
|
T |
C |
G |
C |
A |
A |
C |
C |
A |
T |
T |
C |
C |
A |
T |
C |
C |
T |
A |
T |
T |
A |
T |
G |
T |
C |
T |
C |
T |
T |
G |
T |
G |
A |
T |
A |
C |
A |
A |
C |
G |
A |
C |
G |
C |
T |
C |
C |
A |
T |
A |
C |
G |
G |
T |
G |
T |
G |
C |
T |
T |
A |
A |
G |
G |
A |
G |
T |
C |
A |
A |
C |
A |
C |
C |
G |
T |
T |
G |
C |
C |
C |
C |
C |
C |
T |
A |
T |
G |
A |
T |
A |
T |
A |
C |
T |
C |
A |
A |
G |
A |
A |
G |
A |
G |
A |
T |
A |
T |
A |
C |
A |
G |
T |
A |
A |
T |
G |
T |
G |
C |
C |
C |
A |
C |
G |
A |
A |
G |
G |
A |
A |
A |
G |
T |
G |
C |
T |
G |
G |
C |
A |
A |
A |
A |
T |
A |
T |
A |
G |
T |
A |
C |
T |
C |
G |
A |
A |
G |
C |
A |
C |
A |
G |
G |
G |
C |
C |
G |
A |
A |
A |
A |
A |
T |
T |
A |
A |
T |
G |
C |
A |
C |
C |
A |
C |
C |
G |
A |
G |
C |
T |
G |
G |
A |
C |
G |
G |
A |
C |
G |
T |
A |
A |
T |
T |
C |
A |
A |
A |
G |
T |
G |
A |
C |
C |
C |
C |
T |
A |
A |
G |
A |
G |
C |
C |
G |
C |
A |
T |
G |
C |
C |
G |
A |
T |
G |
G |
C |
G |
A |
A |
C |
G |
G |
C |
T |
T |
A |
G |
A |
G |
C |
A |
G |
T |
T |
A |
C |
C |
A |
C |
A |
G |
G |
G |
A |
A |
A |
A |
G |
G |
G |
G |
C |
C |
C |
A |
A |
C |
T |
C |
T |
A |
A |
T |
T |
A |
A |
G |
G |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
C
|
T
|
A
|
T
|
G
|
T
|
A
|
T
|
G
|
C
|
C
|
T
|
A
|
G
|
C
|
A
|
A
|
C
|
G
|
T/C
|
C
|
G
|
T/C
|
A
|
C
|
T
|
G
|
T
|
C
|
T/C
|
A
|
C
|
A
|
G
|
C
|
G
|
T
|
G
|
G
|
T
|
A
|
G
|
T
|
A
|
T
|
C
|
T
|
A
|
G
|
C
|
G
|
T
|
A
|
C
|
C
|
A
|
G
|
A
|
T
|
C
|
C
|
G
|
G
|
A
|
A
|
G
|
A
|
C
|
T
|
G
|
G
|
T
|
T
|
T
|
C/T
|
A
|
C
|
C
|
A
|
T
|
T
|
G
|
C/T
|
T
|
T
|
C
|
C
|
C
|
A
|
G
|
C
|
G
|
G
|
G
|
T
|
G
|
T
|
G
|
G
|
A
|
C
|
G
|
A
|
G
|
A
|
G
|
C
|
G
|
C
|
G
|
A
|
G
|
T
|
C
|
G
|
G
|
C
|
A
|
A
|
A
|
A
|
G
|
T
|
G
|
A
|
A
|
G
|
G
|
A
|
A
|
G
|
G
|
C
|
A
|
C
|
G/C
|
T
|
C
|
T
|
A
|
T
|
G
|
G
|
G
|
G
|
C
|
G
|
C
|
G
|
A
|
G
|
C
|
T
|
C
|
T
|
G/A
|
G
|
G
|
A
|
T
|
G
|
T
|
A/G
|
A
|
A
|
A
|
T
|
T
|
A
|
C
|
G
|
G
|
G
|
G
|
G
|
C
|
C
|
G
|
C
|
C
|
A
|
G
|
T
|
T
|
T
|
G
|
T
|
T
|
G
|
T
|
A
|
C
|
A
|
G/A
|
T
|
T
|
A
|
A
|
A/C
|
T
|
A
|
C
|
G
|
C
|
C
|
C
|
G
|
G
|
T
|
G
|
T
|
C
|
A
|
G
|
T
|
C/T
|
C/T
|
T
|
G
|
A/C
|
G
|
A
|
C
|
A
|
G
|
G
|
A
|
T
|
T
|
C
|
C
|
T
|
G
|
C
|
G
|
C
|
A
|
A
|
T
|
A
|
T
|
G
|
C/G
|
T
|
T
|
T
|
C
|
C
|
G
|
A
|
G
|
C
|
G
|
G
|
C
|
C
|
C
|
G
|
T
|
C/T
|
G
|
T
|
G
|
A
|
A
|
A
|
G
|
G
|
G
|
G
|
C
|
G/A
|
A
|
A
|
T
|
T
|
T
|
G
|
G
|
T
|
C
|
T
|
C
|
T
|
G
|
A
|
C
|
C
|
G
|
A
|
C
|
|