|
.0 |
.002 |
.346 |
.0 |
.0 |
.843 |
.006 |
.016 |
.0 |
.0 |
.001 |
.0 |
1.0 |
.01 |
.0 |
.001 |
.023 |
.043 |
.0 |
.025 |
.002 |
.051 |
.007 |
.002 |
.0 |
.037 |
.016 |
.002 |
.035 |
.436 |
.112 |
.004 |
.002 |
.103 |
.039 |
.0 |
.008 |
.0 |
.0 |
.037 |
.0 |
.001 |
-- |
.001 |
.589 |
.025 |
.027 |
.134 |
.0 |
.0 |
.0 |
.464 |
.107 |
.005 |
.0 |
.003 |
.889 |
.006 |
.002 |
.0 |
.009 |
.019 |
.0 |
.0 |
.0 |
.0 |
.001 |
.001 |
.008 |
.01 |
.0 |
.003 |
.026 |
.0 |
.274 |
.974 |
.995 |
1.0 |
1.0 |
1.0 |
1.0 |
1.0 |
.004 |
.001 |
.009 |
.001 |
.022 |
.089 |
.003 |
.018 |
.029 |
.008 |
.0 |
.001 |
.0 |
.916 |
.008 |
.121 |
.1 |
.05 |
.001 |
.021 |
.017 |
.0 |
.0 |
.0 |
.024 |
.0 |
.061 |
.0 |
.159 |
.0 |
.037 |
.0 |
.023 |
.028 |
.05 |
.943 |
.139 |
.001 |
.002 |
.002 |
.002 |
.001 |
.078 |
.007 |
.0 |
.0 |
.001 |
.083 |
.005 |
.003 |
.006 |
.011 |
.066 |
.012 |
.0 |
.0 |
.003 |
.0 |
.001 |
.0 |
.02 |
.025 |
.01 |
.0 |
.0 |
.0 |
.001 |
.07 |
.024 |
.006 |
.0 |
.083 |
.012 |
.013 |
.0 |
.005 |
.001 |
.0 |
.01 |
.164 |
.605 |
.006 |
.001 |
.0 |
.006 |
.002 |
.002 |
.002 |
.0 |
.0 |
.0 |
.002 |
.001 |
.0 |
.0 |
.001 |
.481 |
.063 |
.0 |
.033 |
.0 |
.001 |
.004 |
.005 |
.006 |
.075 |
.028 |
.963 |
.012 |
.001 |
.0 |
.08 |
.996 |
.0 |
.093 |
.001 |
.001 |
.033 |
.295 |
.023 |
.007 |
.003 |
.0 |
.0 |
.003 |
.001 |
.112 |
.095 |
.012 |
.001 |
.001 |
.005 |
.036 |
.005 |
.002 |
.0 |
.0 |
.0 |
.011 |
.0 |
.002 |
.0 |
.003 |
.0 |
.0 |
.001 |
.0 |
.001 |
.238 |
.001 |
.0 |
.353 |
.0 |
.008 |
.001 |
.0 |
.001 |
.157 |
.0 |
.024 |
.001 |
.002 |
.0 |
.022 |
.071 |
.0 |
.0 |
.028 |
.0 |
.001 |
.006 |
.001 |
.003 |
.0 |
.019 |
.001 |
.0 |
.003 |
.011 |
.0 |
.069 |
-- |
.001 |
.001 |
.092 |
.0 |
.098 |
.102 |
.014 |
.001 |
.217 |
.008 |
.002 |
.0 |
.001 |
.016 |
.007 |
.001 |
.0 |
.0 |
.006 |
.032 |
.009 |
.0 |
.007 |
.014 |
.0 |
.002 |
.55 |
.011 |
.001 |
.006 |
.0 |
.0 |
.0 |
.001 |
.0 |
.318 |
.0 |
.0 |
.0 |
.001 |
.005 |
.01 |
.001 |
.039 |
.013 |
-- |
.002 |
.015 |
.0 |
.003 |
.0 |
.001 |
.001 |
.006 |
.026 |
.0 |
.002 |
.009 |
.031 |
.001 |
.0 |
.007 |
.028 |
.007 |
.002 |
.006 |
.051 |
.001 |
.002 |
.009 |
.0 |
.001 |
.001 |
.001 |
.033 |
.0 |
.001 |
.001 |
.002 |
.001 |
.002 |
.001 |
.023 |
.033 |
.005 |
.006 |
.0 |
.014 |
.003 |
.178 |
.002 |
.001 |
.243 |
.018 |
.108 |
.003 |
.002 |
.052 |
.001 |
.001 |
.006 |
.005 |
-- |
.842 |
.001 |
.001 |
.001 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
.006 |
.002 |
.003 |
.016 |
.03 |
.008 |
.065 |
.028 |
.241 |
.059 |
.002 |
.246 |
.264 |
.26 |
.071 |
.005 |
.0 |
.0 |
.0 |
.005 |
.005 |
.001 |
.0 |
.006 |
.0 |
.001 |
.012 |
.002 |
.002 |
.001 |
.004 |
.006 |
.1 |
.01 |
.003 |
.058 |
.011 |
.0 |
.003 |
.0 |
.003 |
.0 |
.358 |
.001 |
.365 |
.848 |
.849 |
.002 |
-- |
.003 |
.0 |
.008 |
.002 |
.0 |
.001 |
.01 |
.001 |
.004 |
.008 |
.919 |
.003 |
.002 |
.002 |
.003 |
.061 |
.216 |
.057 |
.025 |
.0 |
.024 |
.373 |
.26 |
.102 |
.023 |
.002 |
.0 |
1.0 |
.0 |
.0 |
.0 |
.002 |
.046 |
.005 |
.012 |
.01 |
.497 |
.001 |
.014 |
.0 |
.0 |
.001 |
.002 |
.003 |
1.0 |
.802 |
.996 |
.215 |
|
Plcb4
|
Plcb4
|
Plcb4
|
Plcb4
|
Plcb4
|
Plcb4
|
Plcb4
|
Plcb4
|
Plcb4
|
Plcb4
|
Plcb4
|
Plcb4
|
Plcb4
|
Plcb4
|
Plcb4
|
Plcb4
|
Plcb4
|
Plcb4
|
Plcb4
|
Plcb4
|
Plcb4
|
Plcb4
|
Plcb4
|
Plcb4
|
Plcb4
|
Plcb4
|
Plcb4
|
Plcb4
|
Plcb4
|
Plcb4
|
Plcb4
|
Plcb4
|
Plcb4
|
Plcb4
|
Plcb4
|
Plcb4
|
Plcb4
|
Plcb4
|
Plcb4
|
Plcb4
|
Plcb4
|
Plcb4
|
Plcb4
|
Plcb4
|
Plcb4
|
Plcb4
|
Plcb4
|
Plcb4
|
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
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--
|
--
|
|
A |
T |
G |
A |
T |
A |
A |
C |
C |
A |
G |
G |
A |
C |
C |
A |
T |
A |
T |
T |
A |
G |
A |
C |
T |
C |
C |
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G |
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T |
A |
G |
T |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
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