|
.0 |
.0 |
.0 |
.006 |
.0 |
.0 |
.0 |
.004 |
.002 |
.006 |
.0 |
.013 |
.001 |
.004 |
.0 |
.001 |
.0 |
.001 |
.0 |
.003 |
.001 |
.002 |
.026 |
.007 |
.006 |
.01 |
.0 |
.0 |
.001 |
.0 |
.026 |
.001 |
.0 |
.0 |
.022 |
.039 |
.038 |
.001 |
.001 |
.072 |
.072 |
.065 |
.171 |
.001 |
.409 |
.08 |
.032 |
.008 |
.002 |
.0 |
.001 |
.011 |
.0 |
.0 |
.001 |
.012 |
.878 |
.519 |
.47 |
.0 |
.008 |
.999 |
.977 |
.985 |
1.0 |
.992 |
1.0 |
.985 |
.997 |
1.0 |
.99 |
.998 |
.961 |
.995 |
.988 |
.997 |
.706 |
.111 |
.318 |
.055 |
.001 |
.0 |
.008 |
.009 |
.0 |
.001 |
.001 |
.011 |
.004 |
.001 |
.03 |
.003 |
.039 |
.018 |
.004 |
.001 |
.133 |
.011 |
.005 |
.042 |
.036 |
.039 |
.098 |
.117 |
.522 |
.001 |
.0 |
.0 |
.0 |
.0 |
.0 |
.0 |
.044 |
.0 |
.005 |
.001 |
.009 |
.01 |
.074 |
.0 |
.093 |
.073 |
.016 |
.032 |
.005 |
.03 |
.006 |
.005 |
.0 |
.024 |
.965 |
.966 |
.099 |
.117 |
.031 |
.07 |
.003 |
.0 |
.004 |
.002 |
.002 |
.001 |
.0 |
.012 |
.002 |
.014 |
.019 |
.019 |
.007 |
.0 |
-- |
.026 |
.002 |
.032 |
.95 |
.124 |
.104 |
.121 |
.147 |
.122 |
.003 |
.0 |
.01 |
.001 |
.0 |
.0 |
.0 |
.009 |
-- |
.022 |
.018 |
.019 |
-- |
-- |
-- |
.005 |
.034 |
.116 |
.102 |
.023 |
.007 |
.051 |
.008 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
.0 |
|
Pde9a
|
Pde9a
|
Pde9a
|
Pde9a
|
Pde9a
|
Pde9a
|
Pde9a
|
Pde9a
|
Pde9a
|
Pde9a
|
Pde9a
|
Pde9a
|
Pde9a
|
Pde9a
|
Pde9a
|
Pde9a
|
Pde9a
|
Pde9a
|
Pde9a
|
Pde9a
|
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
|
G |
A |
T |
T |
T |
A |
A |
A |
G |
T |
C |
T |
C |
T |
T |
T |
A |
G |
T |
T |
T |
C |
A |
A |
A |
G |
A |
T |
G |
T |
A |
C |
G |
G |
T |
A |
A |
G |
G |
C |
C |
T |
G |
T |
G |
G |
T |
G |
G |
A |
T |
G |
G |
G |
G |
A |
A |
G |
G |
C |
G |
G |
G |
G |
A |
T |
G |
G |
G |
A |
G |
C |
G |
C |
C |
A |
A |
G |
A |
A |
C |
T |
A |
C |
C |
G |
C |
A |
G |
A |
A |
G |
A |
A |
A |
C |
G |
T |
G |
A |
C |
G |
T |
C |
G |
T |
G |
T |
T |
G |
C |
C |
C |
A |
A |
G |
G |
A |
C |
A |
A |
A |
A |
A |
C |
G |
C |
T |
C |
A |
T |
G |
G |
G |
C |
C |
T |
G |
G |
T |
T |
G |
C |
C |
A |
G |
A |
G |
C |
T |
A |
G |
T |
G |
T |
T |
G |
G |
A |
G |
A |
A |
A |
T |
G |
A |
A |
C |
C |
G |
T |
A |
T |
G |
T |
T |
T |
G |
G |
A |
A |
C |
T |
G |
A |
C |
G |
A |
G |
C |
A |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
C
|
G
|
G
|
T/C
|
C
|
G
|
G
|
G
|
A
|
C
|
T
|
C
|
T
|
C
|
C
|
C
|
G
|
A
|
C
|
C
|
C
|
G
|
T
|
G
|
G
|
A
|
C
|
C
|
A
|
C
|
C
|
T
|
A
|
A
|
C
|
T
|
G
|
A
|
A
|
T
|
G
|
G
|
A
|
C
|
A
|
A
|
C
|
C
|
A
|
G
|
C
|
C
|
C
|
A
|
A
|
G
|
G
|
A
|
C
|
T
|
T
|
G/T
|
G/A
|
G/T
|
A/C
|
A
|
G/A
|
G/T
|
G/A
|
A/C
|
G/C
|
C/A
|
G/A
|
C/A
|
C/A
|
A/G
|
T
|
A
|
G
|
G
|
T
|
C
|
G
|
T
|
T
|
A
|
T
|
G
|
A
|
G
|
G
|
A
|
G
|
C
|
T
|
T
|
A
|
C
|
A
|
G
|
T
|
A
|
A
|
T
|
A
|
C
|
A
|
A
|
A
|
A
|
A
|
A
|
T
|
C
|
G
|
A
|
A
|
G
|
C/T
|
G
|
G
|
T
|
G
|
T
|
T
|
A
|
T
|
C
|
A
|
G
|
C
|
A
|
A
|
A
|
T
|
T
|
C
|
A
|
A
|
C
|
C
|
C
|
G
|
A
|
G
|
A
|
G
|
A
|
A
|
A
|
T
|
A
|
C
|
T
|
C
|
T/G
|
G/T
|
G/T
|
A/G
|
G/A
|
G
|
G
|
G
|
C
|
T
|
G
|
G
|
T
|
T
|
A
|
C
|
G
|
C
|
A
|
C
|
A
|
A
|
A
|
A
|
G
|
T
|
T
|
C
|
G/A
|
A/G
|
C/T
|
G/A
|
A/C
|
G/A
|
C/A
|
G
|
|