|
.06 |
.0 |
.0 |
.002 |
.001 |
.0 |
.003 |
.0 |
.137 |
.837 |
.114 |
.037 |
.009 |
.007 |
.027 |
.02 |
.22 |
.177 |
.001 |
.157 |
.001 |
-- |
-- |
-- |
-- |
-- |
-- |
.0 |
.012 |
.067 |
.007 |
.002 |
.014 |
.001 |
.998 |
.17 |
.001 |
.0 |
.007 |
.008 |
.026 |
.022 |
.039 |
.0 |
.0 |
.0 |
.998 |
.968 |
.0 |
1.0 |
.001 |
.0 |
.007 |
.045 |
.001 |
.245 |
.093 |
.006 |
.004 |
.001 |
-- |
-- |
.022 |
.854 |
.009 |
.014 |
-- |
.027 |
.016 |
.023 |
.004 |
.994 |
.029 |
.905 |
.0 |
-- |
-- |
.002 |
.971 |
.0 |
.004 |
.006 |
.163 |
.0 |
.0 |
.026 |
.245 |
.022 |
-- |
-- |
-- |
-- |
-- |
.001 |
.024 |
.019 |
.011 |
.027 |
.001 |
.002 |
.694 |
.001 |
.001 |
.001 |
.075 |
.006 |
.003 |
.0 |
.008 |
.001 |
.002 |
.001 |
.0 |
.0 |
.0 |
.001 |
.0 |
.0 |
.001 |
.231 |
.123 |
.016 |
.01 |
.013 |
.046 |
.1 |
.042 |
.028 |
.001 |
.012 |
.003 |
.001 |
.0 |
.001 |
.001 |
.002 |
.0 |
.001 |
.002 |
.0 |
.009 |
.014 |
.002 |
.053 |
.004 |
.009 |
.008 |
.001 |
.0 |
.001 |
.0 |
.001 |
.001 |
.0 |
.014 |
.008 |
.0 |
.0 |
.001 |
.054 |
.006 |
.007 |
.0 |
.0 |
.006 |
.001 |
.0 |
.113 |
.101 |
.002 |
.002 |
.997 |
.917 |
.0 |
.037 |
.017 |
.001 |
.0 |
.001 |
1.0 |
.998 |
.002 |
.0 |
.037 |
.04 |
.008 |
-- |
-- |
.016 |
.007 |
.007 |
.001 |
.0 |
.008 |
.007 |
.024 |
.022 |
.0 |
1.0 |
.001 |
1.0 |
.0 |
.003 |
.418 |
.187 |
.003 |
.004 |
.002 |
.0 |
.008 |
.016 |
.0 |
.001 |
.01 |
.0 |
.0 |
.004 |
.002 |
.007 |
.029 |
.045 |
.057 |
.802 |
.001 |
.001 |
.001 |
.014 |
.0 |
-- |
-- |
.002 |
.014 |
.032 |
.003 |
.009 |
.059 |
.122 |
.0 |
.001 |
.997 |
.017 |
-- |
.003 |
-- |
.009 |
.0 |
.006 |
.041 |
.02 |
.021 |
.001 |
.043 |
.832 |
.014 |
.918 |
.997 |
-- |
.002 |
.001 |
.004 |
.119 |
.028 |
.003 |
.006 |
.001 |
.432 |
.004 |
.0 |
.02 |
.023 |
.034 |
.004 |
.067 |
.036 |
.0 |
.001 |
.042 |
.126 |
.0 |
.935 |
.008 |
.002 |
.001 |
.048 |
.056 |
.0 |
.001 |
.03 |
.0 |
.001 |
.002 |
.071 |
.571 |
.0 |
.041 |
.0 |
.0 |
.0 |
.001 |
.004 |
.217 |
.127 |
.001 |
.075 |
.001 |
.476 |
.036 |
.072 |
.03 |
.001 |
.001 |
.047 |
.173 |
.809 |
.039 |
.023 |
.004 |
.0 |
.002 |
.0 |
.001 |
.003 |
.005 |
.007 |
.001 |
.003 |
.003 |
.015 |
.0 |
.086 |
.021 |
.006 |
.001 |
.016 |
.0 |
.001 |
.001 |
.0 |
.002 |
.0 |
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
|
Pde7b
|
Pde7b
|
Pde7b
|
Pde7b
|
Pde7b
|
Pde7b
|
Pde7b
|
Pde7b
|
Pde7b
|
Pde7b
|
Pde7b
|
Pde7b
|
Pde7b
|
Pde7b
|
Pde7b
|
Pde7b
|
Pde7b
|
Pde7b
|
Pde7b
|
Pde7b
|
Pde7b
|
Pde7b
|
Pde7b
|
Pde7b
|
Pde7b
|
Pde7b
|
Pde7b
|
Pde7b
|
Pde7b
|
Pde7b
|
Pde7b
|
Pde7b
|
Pde7b
|
Pde7b
|
|
G |
A |
G |
C |
A |
C |
G |
T |
T |
G |
T |
C |
T |
A |
G |
C |
T |
A |
T |
C |
A |
G |
A |
T |
C |
C |
G |
C |
T |
C |
T |
T |
C |
A |
G |
T |
A |
C |
T |
T |
A |
C |
A |
T |
C |
C |
T |
A |
G |
A |
C |
A |
T |
G |
A |
A |
T |
G |
G |
T |
T |
C |
G |
T |
C |
C |
T |
G |
G |
G |
A |
G |
T |
G |
T |
C |
C |
T |
T |
T |
T |
C |
T |
C |
A |
C |
T |
G |
G |
C |
C |
G |
T |
G |
A |
G |
T |
A |
T |
C |
T |
G |
T |
C |
A |
A |
G |
C |
A |
C |
T |
A |
A |
C |
T |
G |
C |
T |
G |
A |
C |
A |
G |
C |
T |
G |
A |
C |
A |
G |
T |
A |
A |
T |
C |
A |
A |
T |
T |
T |
C |
T |
A |
T |
C |
A |
A |
T |
T |
T |
C |
A |
T |
C |
G |
C |
G |
A |
C |
C |
G |
C |
G |
C |
G |
T |
G |
G |
C |
A |
A |
G |
T |
G |
G |
T |
A |
A |
T |
T |
C |
C |
A |
A |
T |
A |
T |
A |
G |
C |
T |
A |
T |
G |
C |
G |
C |
G |
C |
G |
A |
C |
G |
A |
G |
A |
T |
G |
C |
C |
A |
A |
T |
A |
A |
T |
C |
G |
C |
G |
G |
G |
G |
A |
C |
C |
A |
T |
G |
T |
C |
G |
G |
G |
G |
G |
G |
T |
G |
G |
A |
T |
C |
T |
A |
C |
T |
T |
G |
G |
G |
T |
G |
G |
A |
T |
G |
G |
C |
C |
C |
A |
C |
C |
A |
T |
G |
A |
G |
G |
G |
G |
A |
T |
C |
C |
T |
C |
A |
C |
C |
T |
C |
G |
A |
C |
T |
A |
A |
T |
C |
A |
G |
C |
G |
G |
G |
C |
G |
T |
G |
A |
T |
G |
A |
G |
G |
A |
G |
C |
T |
T |
A |
A |
G |
A |
G |
C |
G |
G |
G |
A |
C |
C |
A |
G |
T |
G |
T |
T |
T |
A |
G |
G |
G |
G |
C |
A |
A |
A |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
A
|
G
|
T
|
G
|
G
|
T
|
A
|
C
|
C
|
A
|
C
|
G
|
C
|
G
|
C
|
T
|
C
|
C
|
C
|
G
|
C
|
G/T
|
A/G
|
T/G
|
C/T
|
T
|
A
|
G
|
A
|
T
|
G
|
A
|
T
|
G
|
A
|
A
|
G
|
T
|
G
|
C
|
G
|
T
|
C
|
C
|
T
|
T
|
C
|
G
|
A
|
G
|
C/T
|
G
|
C
|
A
|
C
|
T
|
C
|
A
|
A
|
G
|
G
|
A
|
T
|
C
|
T
|
T
|
C
|
A
|
A
|
C
|
C
|
A
|
G
|
G/A
|
C
|
A
|
A
|
G
|
C
|
C
|
C
|
A
|
C
|
T
|
T
|
A
|
C
|
C
|
A
|
A
|
T
|
T
|
C
|
A
|
T
|
A
|
C
|
G
|
C
|
T
|
G
|
C
|
G
|
T
|
G
|
T
|
A
|
T
|
G
|
T
|
C
|
T
|
T
|
T
|
C
|
T
|
G
|
C
|
A
|
G
|
T
|
G
|
A
|
T
|
C
|
A
|
G
|
T
|
G
|
T
|
G
|
G
|
C
|
G
|
A
|
T
|
G
|
C
|
C
|
C
|
T
|
C
|
T
|
C
|
A
|
T
|
G
|
C
|
T/C
|
C
|
T
|
G
|
C
|
T
|
A
|
T
|
A
|
G
|
T
|
T
|
A
|
T
|
A
|
T
|
A
|
C
|
A
|
G/T
|
T
|
A/G
|
A/G
|
A
|
C
|
A
|
A
|
C
|
T
|
G
|
C
|
C
|
T
|
T
|
G
|
G
|
G
|
G
|
G
|
G
|
T
|
T
|
A
|
G
|
G
|
A
|
T
|
A
|
T
|
A
|
T
|
A
|
T
|
A
|
T
|
C
|
A
|
T
|
C
|
T
|
T
|
T
|
G
|
G
|
C
|
G
|
G
|
C
|
C/G
|
G/C
|
C/G
|
G/C
|
G/C
|
C
|
A
|
G
|
T
|
T
|
G
|
C
|
C
|
G
|
T
|
A
|
C
|
A
|
A
|
A
|
T
|
C
|
A
|
A
|
G
|
C
|
T
|
C
|
G
|
T
|
C
|
C
|
A
|
A
|
T
|
G
|
A
|
A
|
G
|
C
|
A
|
A
|
T
|
A
|
T
|
G
|
T
|
T
|
G
|
C
|
A
|
C
|
A
|
T
|
A
|
G/A
|
A/G
|
A
|
A
|
A
|
C
|
A
|
G
|
T
|
G
|
C
|
T
|
A
|
G
|
G
|
A
|
T
|
G
|
G
|
A
|
C
|
T
|
G
|
A
|
C
|
A
|
T
|
T
|
T/G
|
G/T
|
A/G
|
C
|
C
|
G
|
A
|
A
|
T
|
A
|
A
|
C
|
G
|
G
|
G
|
A
|
G
|
T
|
T
|
A
|
C
|
T
|
C
|
T
|
T
|
G
|
A
|
C
|
A
|
G
|
C
|
C
|
G
|
T
|
A
|
A
|
A
|
T
|
G
|
C
|
G
|
|