|
.0 |
.001 |
.001 |
.0 |
.746 |
.0 |
.001 |
.0 |
.0 |
.049 |
.089 |
.008 |
.009 |
.015 |
.003 |
-- |
.026 |
.0 |
.004 |
.004 |
.004 |
.001 |
.207 |
.257 |
.001 |
.023 |
.004 |
.002 |
.004 |
.014 |
.004 |
-- |
-- |
-- |
-- |
-- |
.008 |
.013 |
.005 |
.01 |
.002 |
.036 |
.116 |
.002 |
.093 |
.034 |
.0 |
.0 |
.0 |
.003 |
.0 |
.003 |
.0 |
.0 |
.003 |
.032 |
.794 |
.002 |
.01 |
.072 |
.006 |
.0 |
.003 |
.037 |
.536 |
.001 |
.001 |
.004 |
.393 |
.001 |
.098 |
.09 |
.005 |
.119 |
.099 |
.001 |
.001 |
.049 |
.073 |
.005 |
.0 |
.025 |
.006 |
.074 |
.006 |
.0 |
.022 |
.192 |
.0 |
.0 |
.0 |
.0 |
.985 |
.0 |
.002 |
.0 |
.267 |
.011 |
.0 |
.371 |
.013 |
.005 |
.001 |
.182 |
.045 |
.043 |
.143 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
.079 |
.097 |
.623 |
.044 |
.03 |
.0 |
.01 |
.006 |
.375 |
.0 |
.0 |
.0 |
.002 |
.0 |
.003 |
.016 |
.0 |
.0 |
.012 |
.008 |
.004 |
.001 |
.0 |
.002 |
.009 |
.001 |
.024 |
.004 |
.004 |
.036 |
.017 |
.03 |
.0 |
.001 |
.041 |
.015 |
.18 |
.033 |
.0 |
.828 |
.003 |
.0 |
.22 |
-- |
-- |
.003 |
.001 |
.001 |
.006 |
.0 |
.004 |
.0 |
.995 |
.0 |
.001 |
.276 |
.001 |
.002 |
.012 |
.0 |
.006 |
.005 |
.001 |
.0 |
1.0 |
.987 |
1.0 |
.967 |
.971 |
.219 |
.34 |
.043 |
.022 |
.0 |
.0 |
.0 |
.001 |
.004 |
.0 |
.09 |
.054 |
.001 |
-- |
-- |
.0 |
.0 |
.119 |
.712 |
.429 |
.328 |
.388 |
.434 |
.593 |
.078 |
.026 |
.132 |
.141 |
.138 |
.112 |
.023 |
.515 |
.008 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
.808 |
.14 |
.0 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
.004 |
.494 |
.025 |
.011 |
.002 |
.0 |
.021 |
.035 |
.519 |
.004 |
.002 |
.93 |
.001 |
.001 |
.001 |
|
Pde5a
|
Pde5a
|
Pde5a
|
Pde5a
|
Pde5a
|
Pde5a
|
Pde5a
|
Pde5a
|
Pde5a
|
Pde5a
|
Pde5a
|
Pde5a
|
Pde5a
|
Pde5a
|
Pde5a
|
Pde5a
|
Pde5a
|
Pde5a
|
Pde5a
|
Pde5a
|
Pde5a
|
Pde5a
|
Pde5a
|
Pde5a
|
Pde5a
|
Pde5a
|
Pde5a
|
Pde5a
|
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
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--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
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--
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--
|
--
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--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
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--
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--
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--
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--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
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--
|
--
|
--
|
--
|
--
|
--
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|
--
|
--
|
--
|
--
|
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|
--
|
--
|
--
|
--
|
--
|
--
|
--
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--
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--
|
--
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--
|
--
|
--
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--
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--
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--
|
--
|
--
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--
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--
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--
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--
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--
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--
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--
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--
|
--
|
--
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--
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--
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--
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--
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--
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--
|
--
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--
|
--
|
--
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--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
|
C |
G |
T |
G |
G |
A |
G |
A |
T |
G |
G |
T |
A |
T |
A |
C |
T |
A |
G |
T |
T |
C |
G |
A |
G |
T |
C |
G |
A |
A |
T |
G |
A |
T |
A |
A |
C |
C |
A |
C |
T |
A |
C |
G |
A |
T |
A |
A |
C |
T |
T |
C |
G |
T |
T |
C |
T |
G |
C |
G |
T |
C |
C |
T |
T |
A |
T |
C |
T |
T |
G |
A |
G |
A |
T |
G |
C |
G |
G |
T |
G |
C |
A |
A |
C |
G |
T |
T |
C |
A |
A |
T |
C |
T |
T |
T |
T |
A |
C |
T |
C |
A |
A |
T |
C |
C |
A |
A |
A |
A |
C |
G |
C |
C |
A |
G |
G |
A |
A |
T |
A |
C |
G |
A |
T |
C |
G |
T |
A |
G |
T |
T |
T |
G |
A |
T |
A |
C |
T |
T |
T |
T |
G |
A |
G |
A |
C |
G |
G |
A |
G |
G |
A |
G |
T |
C |
G |
A |
A |
T |
C |
G |
A |
C |
T |
G |
C |
C |
G |
G |
T |
T |
C |
T |
C |
C |
T |
T |
T |
A |
A |
C |
T |
T |
A |
T |
T |
A |
G |
G |
A |
T |
A |
A |
A |
C |
C |
T |
T |
C |
G |
T |
A |
A |
T |
A |
A |
G |
C |
C |
A |
T |
C |
G |
A |
A |
G |
A |
C |
A |
T |
T |
G |
T |
C |
T |
T |
G |
G |
C |
C |
T |
T |
G |
G |
T |
T |
C |
C |
T |
T |
C |
C |
C |
A |
C |
A |
T |
G |
T |
C |
C |
A |
C |
T |
A |
A |
A |
A |
T |
A |
C |
A |
C |
G |
C |
G |
A |
G |
A |
T |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
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|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
T
|
A
|
C
|
A
|
T
|
C
|
A
|
G
|
C
|
A
|
A
|
C
|
G
|
G
|
G
|
C/T
|
G
|
G
|
C
|
G
|
C
|
T
|
G/A
|
T
|
A
|
C
|
G
|
A
|
G
|
G
|
C
|
A
|
T
|
C
|
G
|
G
|
T
|
T
|
G
|
T
|
C
|
G
|
T
|
A
|
T
|
A
|
G
|
G
|
T
|
C
|
C
|
T
|
A
|
C
|
A
|
T
|
C
|
A
|
T
|
A
|
A
|
T
|
T
|
A
|
C
|
G
|
C
|
T
|
C
|
C
|
T
|
T
|
A
|
G
|
C
|
C
|
T
|
A
|
A
|
C
|
A
|
T
|
G
|
G
|
T
|
A
|
A
|
C
|
T
|
T
|
G
|
C
|
G
|
A
|
C
|
G
|
G
|
G
|
T
|
C
|
A
|
T
|
G
|
T/C
|
C/T
|
T
|
G
|
A/T
|
T
|
T
|
T
|
A
|
A
|
T
|
C
|
T
|
T
|
G
|
A/T
|
T/C
|
A/G
|
T
|
T
|
A/G
|
G
|
T
|
G/A
|
C
|
A/G
|
A
|
C
|
C
|
G
|
A
|
G
|
A
|
G
|
A
|
C
|
C
|
C
|
C
|
T
|
G
|
A
|
G
|
T
|
T
|
C
|
C
|
A
|
A
|
G
|
A
|
C
|
T
|
A
|
G
|
G
|
A
|
A
|
C
|
G
|
T
|
C
|
A
|
A
|
T
|
T
|
T
|
C
|
A
|
G
|
C
|
C/T
|
C/T
|
C
|
C
|
A
|
G
|
G
|
T
|
C
|
C
|
G
|
C
|
C
|
G
|
A
|
A
|
G
|
C
|
A/T
|
A/T
|
G
|
G
|
T
|
T/C
|
C
|
T
|
C
|
C
|
G
|
G
|
C
|
G
|
G
|
C
|
T
|
T
|
G
|
C
|
T
|
A
|
G
|
G
|
A
|
G
|
G
|
G
|
A
|
A
|
A
|
C
|
T
|
A
|
C
|
G/A
|
G/A
|
C/T
|
T
|
C
|
G
|
A
|
C
|
C
|
C
|
T
|
G
|
G
|
C
|
G
|
T
|
T
|
G
|
A
|
G
|
C
|
A
|
C
|
T
|
T
|
G
|
T
|
A
|
C
|
G
|
G
|
G
|
A
|
C
|
T
|
G
|
T
|
T
|
T
|
C
|
T
|
A
|
C
|
G
|
|