|
.292 |
.001 |
.0 |
.0 |
.0 |
.997 |
.097 |
.29 |
.064 |
.027 |
.005 |
.0 |
.0 |
.0 |
.0 |
.003 |
.001 |
.002 |
.012 |
.004 |
.001 |
-- |
.0 |
.0 |
.993 |
.0 |
.001 |
.951 |
.0 |
.0 |
.0 |
.001 |
.0 |
.006 |
.001 |
.0 |
.271 |
.004 |
.001 |
.0 |
.001 |
.0 |
.001 |
.176 |
.012 |
.267 |
.043 |
.633 |
.61 |
.0 |
.0 |
.0 |
.001 |
.005 |
.0 |
.0 |
.0 |
.001 |
.001 |
.0 |
.0 |
.0 |
.0 |
.0 |
.005 |
.0 |
.856 |
.002 |
.018 |
.004 |
.029 |
.019 |
.0 |
.001 |
.0 |
.001 |
.003 |
.049 |
.001 |
.0 |
.0 |
.86 |
.003 |
.0 |
.006 |
.004 |
.005 |
.001 |
.017 |
.054 |
.001 |
.0 |
.003 |
.0 |
.001 |
.002 |
.001 |
.002 |
.013 |
.065 |
.001 |
.014 |
.028 |
.002 |
.0 |
.0 |
.862 |
.006 |
.0 |
.001 |
.085 |
.0 |
.0 |
.002 |
-- |
-- |
.001 |
.002 |
.004 |
.0 |
.003 |
.0 |
.0 |
.0 |
.05 |
.001 |
.096 |
-- |
-- |
-- |
-- |
-- |
.256 |
.068 |
.001 |
.019 |
.0 |
.001 |
.03 |
.0 |
.0 |
.0 |
.015 |
.0 |
.028 |
.001 |
.0 |
.0 |
.598 |
.042 |
.004 |
.019 |
.006 |
.997 |
.784 |
.0 |
.043 |
.002 |
.0 |
.002 |
.017 |
.001 |
.005 |
.265 |
.003 |
.135 |
.005 |
.001 |
.002 |
.999 |
-- |
-- |
.08 |
.002 |
.03 |
.001 |
.001 |
.024 |
.0 |
.258 |
.0 |
.0 |
.126 |
.002 |
.001 |
.063 |
.0 |
.0 |
.001 |
.007 |
.001 |
.162 |
.109 |
.001 |
.002 |
.048 |
.001 |
.001 |
.0 |
.015 |
.002 |
.153 |
.0 |
-- |
.032 |
.0 |
.0 |
.055 |
.004 |
.004 |
.022 |
.001 |
.001 |
.239 |
.001 |
.0 |
.001 |
.001 |
.007 |
.005 |
.003 |
.054 |
.0 |
.0 |
.0 |
.003 |
.005 |
.0 |
.0 |
.1 |
.002 |
.0 |
.0 |
.556 |
.0 |
.114 |
.116 |
.153 |
.343 |
.008 |
.0 |
.019 |
.001 |
-- |
.0 |
.001 |
.0 |
.055 |
.011 |
.005 |
.0 |
.0 |
.003 |
.0 |
.0 |
.0 |
.0 |
.0 |
.004 |
.0 |
.002 |
.003 |
.006 |
.004 |
.283 |
.004 |
.0 |
.171 |
.806 |
.032 |
.117 |
.009 |
.004 |
.0 |
.0 |
.001 |
.006 |
.0 |
.083 |
.005 |
.008 |
.0 |
.001 |
.034 |
.014 |
.176 |
.0 |
.002 |
.001 |
.008 |
.017 |
.001 |
.662 |
.0 |
.005 |
.001 |
.0 |
.033 |
.0 |
.0 |
.001 |
.0 |
.004 |
.035 |
.0 |
.0 |
.978 |
.982 |
.0 |
.013 |
.013 |
.003 |
.016 |
.002 |
.012 |
.239 |
.0 |
.0 |
.037 |
.014 |
.0 |
.008 |
.005 |
.0 |
.001 |
.006 |
.005 |
.22 |
.01 |
.001 |
.0 |
.0 |
.011 |
.365 |
.013 |
.003 |
.042 |
.001 |
.0 |
.008 |
.005 |
.002 |
.003 |
.127 |
-- |
-- |
.869 |
.0 |
.09 |
.015 |
.005 |
.109 |
.057 |
.024 |
.025 |
-- |
.037 |
.007 |
.002 |
.136 |
.106 |
.339 |
.0 |
.001 |
.062 |
.001 |
.002 |
.156 |
.001 |
.001 |
.002 |
.001 |
.018 |
.003 |
.013 |
.0 |
.006 |
.0 |
.002 |
.0 |
.001 |
.002 |
.06 |
.002 |
.017 |
.002 |
.049 |
.005 |
.009 |
.66 |
.004 |
.0 |
.016 |
.027 |
.0 |
.0 |
.002 |
.012 |
.134 |
.012 |
.024 |
.003 |
.023 |
.035 |
.022 |
.0 |
.002 |
.003 |
.396 |
.135 |
.001 |
.987 |
.99 |
.0 |
.006 |
.003 |
.0 |
.004 |
.001 |
.029 |
.006 |
.0 |
.331 |
.005 |
.138 |
.001 |
.002 |
.002 |
.558 |
.0 |
.014 |
.243 |
.002 |
.025 |
.006 |
.051 |
.0 |
.062 |
.09 |
.005 |
.0 |
.104 |
.078 |
.157 |
.022 |
.075 |
.001 |
.023 |
.0 |
.01 |
.001 |
.0 |
.859 |
.06 |
.0 |
.0 |
.009 |
.004 |
.001 |
.0 |
.001 |
.007 |
.0 |
.292 |
.01 |
.081 |
.001 |
.0 |
.009 |
.001 |
.0 |
.004 |
.005 |
.01 |
.009 |
.0 |
.0 |
.008 |
.004 |
.0 |
.002 |
.006 |
.0 |
.099 |
.009 |
1.0 |
.0 |
.0 |
.052 |
.003 |
.029 |
.189 |
.002 |
.0 |
.001 |
.0 |
.01 |
.0 |
.026 |
.012 |
.048 |
.0 |
.0 |
.0 |
.013 |
.009 |
.001 |
.001 |
.998 |
.984 |
.996 |
.068 |
.004 |
.002 |
.146 |
.001 |
.001 |
.0 |
.0 |
.0 |
.015 |
.002 |
.0 |
.0 |
.0 |
.004 |
.0 |
.0 |
.0 |
.002 |
.032 |
.003 |
.0 |
.002 |
1.0 |
.03 |
.003 |
.0 |
.0 |
.003 |
.0 |
.002 |
.001 |
.0 |
.0 |
.931 |
.0 |
.003 |
.001 |
.068 |
.04 |
.007 |
.001 |
.14 |
.004 |
.195 |
.001 |
.001 |
.059 |
.084 |
.036 |
.0 |
.005 |
.001 |
.0 |
.004 |
.0 |
.001 |
.271 |
.0 |
.107 |
.005 |
.002 |
.0 |
.0 |
.048 |
.041 |
.863 |
.0 |
.006 |
.0 |
.001 |
.0 |
.0 |
.001 |
.122 |
.001 |
.911 |
.014 |
.033 |
.001 |
.0 |
.001 |
.037 |
.041 |
.007 |
.222 |
.379 |
.006 |
.006 |
.001 |
.0 |
.0 |
.015 |
.0 |
.007 |
.001 |
.009 |
.064 |
.001 |
.011 |
.002 |
.012 |
.006 |
.005 |
.309 |
.005 |
.069 |
.001 |
.0 |
.001 |
.015 |
.092 |
.002 |
.031 |
.008 |
.006 |
.06 |
.013 |
.009 |
.002 |
.001 |
-- |
-- |
.256 |
.01 |
.036 |
.033 |
.03 |
.026 |
.0 |
.007 |
.0 |
.03 |
.999 |
.957 |
.001 |
.004 |
.959 |
.018 |
.12 |
.005 |
.001 |
.002 |
.619 |
.004 |
.001 |
.579 |
.0 |
.736 |
.003 |
.009 |
.001 |
.064 |
.323 |
.064 |
.536 |
.042 |
.174 |
.24 |
.122 |
.22 |
.202 |
.0 |
.0 |
.0 |
.001 |
.0 |
.003 |
.098 |
.0 |
.005 |
.0 |
.008 |
.0 |
.0 |
.0 |
.0 |
.0 |
.0 |
.001 |
.005 |
.0 |
.0 |
.055 |
.191 |
.95 |
.002 |
.0 |
.0 |
.0 |
.0 |
.0 |
.001 |
.127 |
.0 |
.01 |
.008 |
.0 |
.002 |
.012 |
.0 |
.119 |
.004 |
.0 |
.006 |
.959 |
-- |
.078 |
.286 |
.036 |
.003 |
.007 |
.008 |
-- |
.063 |
.0 |
.017 |
.811 |
.992 |
.011 |
.015 |
.394 |
.07 |
.07 |
.043 |
.187 |
.062 |
.042 |
-- |
-- |
.05 |
.003 |
.003 |
.088 |
.001 |
.0 |
.035 |
.005 |
.161 |
.001 |
.0 |
.314 |
.087 |
.031 |
.019 |
.022 |
.384 |
.089 |
.027 |
.029 |
.037 |
.132 |
.084 |
.913 |
.521 |
.004 |
.012 |
.004 |
.047 |
.016 |
.099 |
.237 |
.199 |
-- |
-- |
-- |
-- |
.002 |
.011 |
.959 |
.012 |
.039 |
.206 |
.555 |
.008 |
.016 |
.019 |
.001 |
.0 |
1.0 |
.999 |
.0 |
.05 |
.033 |
.008 |
.959 |
.047 |
.0 |
.037 |
.001 |
.001 |
.001 |
.039 |
.013 |
.002 |
.003 |
.001 |
.0 |
.323 |
.007 |
.0 |
.561 |
.03 |
.03 |
.001 |
.001 |
.142 |
.043 |
.0 |
.0 |
.001 |
.005 |
.004 |
.002 |
.793 |
.004 |
.02 |
.046 |
.0 |
.0 |
.002 |
.0 |
.103 |
.424 |
.001 |
.01 |
.086 |
.262 |
.0 |
.002 |
.001 |
.0 |
.0 |
.0 |
.057 |
.313 |
.249 |
.001 |
.126 |
.0 |
.006 |
.001 |
.962 |
.0 |
.001 |
.02 |
.0 |
.969 |
.004 |
.003 |
.001 |
.173 |
.0 |
.001 |
.012 |
.009 |
.001 |
.001 |
.141 |
.095 |
.001 |
.011 |
.0 |
.42 |
.005 |
.015 |
.002 |
.019 |
.002 |
.0 |
.0 |
1.0 |
.001 |
.004 |
.239 |
.0 |
.016 |
.042 |
.055 |
.002 |
.002 |
.053 |
.058 |
.068 |
.006 |
.011 |
.012 |
.849 |
.0 |
.0 |
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
LOC100911367
|
LOC100911367
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
Fgf1
|
Fgf1
|
Fgf1
|
Fgf1
|
Fgf1
|
Fgf1
|
Fgf1
|
Fgf1
|
Fgf1
|
Fgf1
|
Fgf1
|
Fgf1
|
Fgf1
|
Fgf1
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
Spry4
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
|
Nr3c1
|
Nr3c1
|
Nr3c1
|
Nr3c1
|
Nr3c1
|
Nr3c1
|
Nr3c1
|
Nr3c1
|
Nr3c1
|
Nr3c1
|
Nr3c1
|
Nr3c1
|
Nr3c1
|
Nr3c1
|
Nr3c1
|
Nr3c1
|
Nr3c1
|
Nr3c1
|
Nr3c1
|
Nr3c1
|
Nr3c1
|
Nr3c1
|
Nr3c1
|
Nr3c1
|
Nr3c1
|
Nr3c1
|
Nr3c1
|
Nr3c1
|
Nr3c1
|
Nr3c1
|
Nr3c1
|
Nr3c1
|
Nr3c1
|
Nr3c1
|
Nr3c1
|
Nr3c1
|
Nr3c1
|
Nr3c1
|
Nr3c1
|
Nr3c1
|
Nr3c1
|
Nr3c1
|
Nr3c1
|
Nr3c1
|
Nr3c1
|
Nr3c1
|
Nr3c1
|
Nr3c1
|
Nr3c1
|
Nr3c1
|
Nr3c1
|
Nr3c1
|
Nr3c1
|
Nr3c1
|
Nr3c1
|
Nr3c1
|
Nr3c1
|
Nr3c1
|
Nr3c1
|
Nr3c1
|
Nr3c1
|
Nr3c1
|
Nr3c1
|
Nr3c1
|
Nr3c1
|
Nr3c1
|
Nr3c1
|
Nr3c1
|
Nr3c1
|
Nr3c1
|
Nr3c1
|
Nr3c1
|
Nr3c1
|
Nr3c1
|
Nr3c1
|
Nr3c1
|
Nr3c1
|
Nr3c1
|
Nr3c1
|
Nr3c1
|
Nr3c1
|
Nr3c1
|
Nr3c1
|
Nr3c1
|
Nr3c1
|
Nr3c1
|
Nr3c1
|
Nr3c1
|
Nr3c1
|
Nr3c1
|
Nr3c1
|
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
|
G |
T |
G |
G |
T |
C |
C |
A |
C |
A |
G |
T |
G |
G |
G |
G |
G |
T |
G |
A |
C |
C |
G |
C |
G |
T |
A |
A |
T |
C |
T |
C |
A |
A |
A |
T |
T |
T |
T |
A |
T |
C |
G |
C |
C |
G |
A |
T |
T |
G |
A |
C |
A |
T |
T |
G |
T |
C |
A |
A |
A |
G |
G |
C |
A |
T |
G |
C |
T |
A |
C |
A |
C |
C |
A |
A |
G |
T |
C |
A |
T |
G |
C |
G |
A |
A |
C |
T |
G |
C |
T |
A |
T |
T |
T |
T |
T |
C |
A |
G |
C |
A |
G |
C |
C |
G |
C |
A |
A |
T |
C |
C |
C |
G |
A |
C |
G |
T |
T |
A |
T |
A |
T |
T |
G |
C |
A |
T |
C |
C |
G |
A |
C |
A |
A |
C |
T |
G |
G |
C |
C |
A |
C |
C |
G |
A |
A |
G |
T |
A |
C |
C |
G |
G |
T |
G |
A |
A |
G |
G |
C |
A |
C |
A |
G |
A |
C |
C |
G |
A |
A |
G |
T |
A |
T |
T |
A |
A |
A |
C |
G |
A |
C |
C |
T |
T |
A |
G |
C |
T |
A |
G |
A |
G |
A |
C |
A |
A |
T |
C |
A |
G |
G |
C |
G |
G |
G |
C |
C |
C |
A |
G |
A |
A |
A |
G |
A |
A |
A |
A |
C |
T |
G |
A |
C |
A |
T |
C |
G |
A |
C |
A |
G |
T |
C |
C |
G |
T |
G |
G |
C |
G |
C |
C |
G |
A |
G |
C |
C |
T |
G |
A |
C |
A |
A |
T |
G |
G |
A |
G |
T |
C |
T |
T |
C |
A |
G |
A |
T |
G |
C |
A |
T |
G |
T |
A |
T |
A |
G |
G |
C |
T |
G |
T |
G |
A |
G |
G |
G |
T |
C |
A |
G |
G |
A |
C |
A |
C |
T |
A |
G |
G |
G |
G |
T |
C |
C |
C |
T |
G |
G |
C |
A |
G |
C |
T |
A |
A |
G |
C |
A |
T |
C |
A |
A |
G |
G |
G |
G |
G |
T |
A |
C |
C |
T |
G |
G |
C |
T |
C |
G |
T |
C |
A |
C |
C |
G |
G |
G |
T |
T |
C |
T |
G |
C |
A |
A |
T |
A |
T |
A |
G |
G |
G |
G |
A |
G |
C |
G |
T |
G |
G |
G |
T |
G |
T |
C |
T |
G |
C |
G |
T |
C |
G |
A |
T |
G |
A |
A |
A |
A |
G |
C |
C |
T |
G |
G |
A |
G |
A |
A |
C |
C |
G |
C |
A |
T |
G |
C |
T |
G |
T |
G |
G |
G |
T |
A |
G |
A |
A |
G |
T |
C |
C |
C |
G |
C |
A |
A |
A |
G |
G |
T |
T |
A |
C |
C |
G |
T |
G |
G |
T |
A |
G |
T |
G |
A |
G |
C |
G |
T |
C |
C |
A |
G |
C |
A |
G |
A |
G |
A |
C |
T |
A |
C |
A |
C |
G |
A |
A |
A |
G |
C |
T |
G |
G |
C |
A |
G |
T |
C |
C |
G |
G |
G |
T |
A |
A |
G |
T |
A |
T |
C |
G |
A |
G |
A |
A |
T |
T |
G |
A |
G |
A |
T |
G |
T |
A |
A |
C |
C |
C |
A |
G |
T |
A |
G |
G |
A |
T |
C |
A |
A |
G |
G |
C |
A |
G |
T |
G |
T |
T |
C |
G |
G |
T |
G |
G |
G |
A |
A |
G |
C |
G |
A |
G |
C |
T |
C |
C |
T |
A |
A |
A |
T |
G |
A |
T |
C |
A |
T |
T |
G |
C |
A |
A |
A |
C |
A |
A |
A |
A |
C |
C |
T |
C |
A |
G |
G |
G |
G |
C |
A |
C |
C |
C |
T |
A |
G |
T |
C |
C |
T |
A |
G |
C |
T |
A |
T |
A |
C |
A |
G |
T |
G |
G |
A |
G |
A |
A |
C |
G |
G |
C |
G |
C |
C |
T |
G |
A |
G |
T |
A |
A |
T |
A |
C |
C |
C |
T |
G |
G |
T |
C |
A |
C |
G |
C |
A |
A |
C |
T |
A |
C |
T |
A |
T |
T |
G |
G |
G |
C |
C |
T |
C |
A |
C |
A |
C |
C |
A |
G |
C |
T |
G |
C |
G |
A |
A |
A |
C |
G |
G |
A |
G |
C |
T |
C |
C |
A |
G |
C |
C |
A |
T |
C |
G |
C |
T |
G |
A |
A |
G |
C |
G |
A |
G |
T |
A |
C |
C |
G |
T |
T |
G |
A |
A |
A |
C |
G |
T |
G |
T |
C |
A |
A |
G |
C |
A |
G |
A |
T |
G |
G |
A |
A |
T |
A |
G |
G |
T |
T |
C |
G |
C |
A |
T |
G |
A |
A |
C |
G |
C |
A |
G |
A |
T |
G |
G |
T |
T |
C |
A |
G |
A |
G |
T |
G |
T |
A |
A |
A |
C |
C |
A |
A |
G |
C |
T |
A |
T |
A |
C |
T |
G |
A |
C |
C |
G |
T |
A |
T |
A |
A |
G |
G |
G |
G |
C |
A |
T |
C |
G |
C |
A |
A |
T |
A |
T |
C |
C |
T |
A |
A |
T |
G |
C |
C |
T |
T |
G |
A |
T |
G |
A |
G |
T |
G |
C |
T |
T |
T |
T |
C |
A |
C |
G |
A |
T |
C |
G |
G |
T |
A |
G |
A |
T |
T |
G |
C |
G |
G |
T |
T |
A |
G |
A |
A |
T |
C |
C |
C |
T |
T |
C |
G |
A |
A |
G |
T |
T |
G |
A |
A |
A |
G |
C |
T |
A |
A |
G |
C |
T |
A |
T |
C |
A |
T |
A |
T |
G |
C |
G |
C |
A |
A |
C |
A |
C |
A |
G |
T |
A |
G |
T |
A |
G |
A |
A |
G |
C |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
A
|
C
|
C
|
A
|
C
|
T
|
T
|
C
|
A
|
T
|
T
|
C
|
A
|
A
|
A
|
C
|
A
|
G
|
A
|
T
|
T
|
A
|
C
|
T
|
A
|
A
|
T
|
G
|
C
|
T
|
C
|
T
|
G
|
G
|
G
|
C
|
C
|
C
|
C
|
C
|
C
|
A
|
A
|
T
|
T
|
A
|
G
|
A
|
A
|
A
|
G
|
T
|
T
|
C
|
C
|
A
|
C
|
A
|
G
|
C
|
T
|
A
|
A
|
T
|
G
|
C
|
A
|
A
|
C
|
G
|
T
|
G
|
T
|
T
|
C
|
G
|
A
|
C
|
T
|
T
|
C
|
A
|
T
|
A
|
G
|
G
|
T
|
G
|
A
|
T
|
G
|
G
|
C
|
C
|
C
|
C
|
G
|
G
|
G
|
A
|
A
|
T
|
A
|
T
|
T
|
A
|
A
|
T
|
G
|
C
|
A
|
T
|
T
|
A
|
C
|
G
|
A
|
C
|
C
|
G
|
G
|
G
|
C
|
C
|
A
|
T
|
C
|
C
|
T
|
T
|
A
|
C
|
T
|
G
|
G
|
A
|
A
|
T
|
C
|
T
|
T
|
G
|
T
|
T
|
T
|
G
|
G
|
A
|
C
|
G
|
A
|
T
|
T
|
A
|
C
|
T
|
G
|
G
|
A
|
A
|
T
|
G
|
T
|
C
|
A
|
C
|
T
|
T
|
C
|
G
|
T
|
A
|
C
|
G
|
A
|
C
|
G
|
G
|
G
|
A
|
A
|
G
|
T
|
T
|
G
|
C
|
G
|
A
|
A
|
G
|
C
|
A
|
G
|
C
|
G
|
A
|
G
|
T
|
G
|
T
|
A/C
|
A
|
C
|
T
|
C
|
A
|
A
|
T
|
A
|
A
|
G
|
A
|
T
|
G
|
G
|
A
|
G
|
G
|
G
|
C
|
T
|
C
|
A
|
G
|
T
|
G
|
C
|
T
|
A
|
G
|
T
|
G
|
A
|
C
|
A
|
T
|
A
|
C
|
A
|
A
|
T
|
A
|
T
|
T
|
T
|
G
|
T
|
A
|
T
|
C
|
A
|
G
|
A
|
T
|
G
|
C
|
A
|
A
|
G
|
A
|
C
|
T
|
C
|
C
|
T
|
G
|
A
|
G
|
A
|
A
|
T
|
G
|
G
|
A
|
C
|
T
|
C
|
G
|
T
|
A
|
T
|
C
|
C
|
G
|
T
|
G
|
A
|
T
|
A
|
C
|
G
|
G
|
T
|
A
|
G
|
A
|
G
|
T
|
C
|
G
|
A
|
A
|
T
|
T
|
C
|
T
|
T
|
T
|
C
|
A
|
A
|
T
|
G
|
A
|
T
|
A
|
T
|
C
|
A
|
G
|
G
|
C
|
T
|
T
|
G
|
A
|
T
|
A
|
T
|
A
|
C
|
G
|
T
|
T
|
G
|
T
|
T
|
G
|
C
|
G
|
A
|
A
|
A
|
G
|
T
|
T
|
A
|
A
|
A
|
C
|
C
|
T
|
G
|
A
|
T
|
G
|
G
|
C
|
G
|
G
|
C
|
A
|
A
|
A
|
A
|
G
|
A
|
T
|
C
|
G
|
A
|
A
|
C
|
C
|
A
|
C
|
T
|
C
|
T
|
T
|
T
|
C
|
T
|
A
|
C
|
C
|
A
|
G
|
G
|
G
|
G
|
A
|
T
|
A
|
C
|
A
|
A
|
G
|
A
|
G
|
G
|
G
|
T
|
A
|
G
|
G
|
G
|
A
|
T
|
C
|
A
|
C
|
A
|
A
|
A
|
C
|
G
|
A
|
G
|
G
|
A
|
A
|
G
|
G
|
T
|
C
|
A
|
T
|
G
|
G
|
A
|
A
|
C
|
C
|
T
|
T
|
T
|
A
|
C
|
T
|
A
|
C
|
G
|
A
|
C
|
C
|
G
|
C
|
G
|
A
|
C
|
T
|
T
|
T
|
A
|
T
|
C
|
A
|
G
|
A
|
G
|
T
|
C
|
C
|
T
|
G
|
T
|
T
|
G
|
T
|
T
|
A
|
T
|
C
|
A
|
A
|
A
|
G
|
T
|
C
|
T
|
T
|
C
|
A
|
A
|
A
|
G
|
G
|
A
|
C
|
C
|
C
|
T
|
T
|
G
|
A
|
G
|
G
|
C
|
A
|
A
|
G
|
A
|
G
|
C
|
A
|
G
|
G
|
C
|
T
|
T
|
T
|
G
|
A
|
C
|
G
|
T
|
A
|
G
|
G
|
T
|
G
|
G
|
A
|
C
|
T
|
T
|
A
|
C
|
A
|
C
|
C
|
G
|
A
|
A
|
C
|
A
|
A
|
T
|
G
|
G
|
A
|
T
|
G/A
|
G
|
A
|
A
|
C
|
A
|
A
|
C
|
T
|
G
|
G
|
C
|
T
|
G
|
G
|
T
|
G
|
C
|
C
|
A
|
T
|
T
|
G
|
T
|
T
|
G
|
G
|
T
|
G
|
T
|
A
|
C
|
T
|
C
|
A
|
A
|
T
|
A
|
T
|
T
|
G
|
T
|
T
|
C
|
G
|
A
|
C
|
G
|
T
|
C
|
G
|
A
|
T
|
C
|
G
|
C
|
C
|
T
|
C
|
A
|
C
|
T
|
A
|
G
|
A
|
C
|
G
|
A
|
T
|
T
|
G
|
T
|
T
|
T
|
C
|
A
|
G
|
A
|
A
|
G
|
G
|
C
|
G
|
T
|
T
|
T
|
C
|
A
|
A
|
C
|
T
|
G
|
T
|
A
|
T
|
G
|
G
|
T
|
A
|
G
|
T
|
C
|
G
|
A
|
C
|
A
|
A
|
A
|
A
|
T
|
C
|
T
|
G
|
T
|
G
|
T
|
T
|
G
|
T
|
A
|
G
|
A
|
T
|
A
|
G
|
C
|
G
|
G
|
A
|
A
|
G
|
A
|
T
|
C
|
T
|
T
|
G
|
A
|
T
|
A
|
C
|
C
|
T
|
A
|
T
|
C
|
A
|
G
|
G
|
C
|
T
|
A
|
G
|
A
|
C
|
C
|
T
|
A
|
A
|
C
|
C
|
C
|
G
|
A/C
|
A/T
|
C/T
|
A
|
C
|
A
|
A
|
T
|
G
|
T
|
A
|
T
|
G
|
A
|
T
|
C
|
A
|
T
|
G
|
G
|
C
|
G
|
A
|
C
|
C
|
C
|
A
|
T
|
G
|
G
|
C
|
T
|
G
|
G
|
T
|
A
|
A
|
G
|
A
|
T
|
C
|
A
|
A
|
C
|
C
|
A
|
G
|
A
|
G
|
A
|
A
|
C
|
C
|
T
|
C
|
G
|
G
|
T
|
G
|
G
|
A
|
G
|
C
|
T
|
G
|
G
|
G
|
C
|
T
|
G
|
T
|
T
|
A
|
C
|
T
|
C
|
C
|
G
|
T
|
A
|
A
|
A
|
T
|
G
|
C
|
G
|
A
|
T
|
C
|
C
|
C
|
T
|
C
|
A
|
G
|
C
|
C
|
T
|
C
|
A
|
T
|
T
|
C
|
C
|
T
|
G
|
C
|
A
|
C
|
A
|
C
|
C
|
T
|
C
|
A
|
A
|
C
|
G
|
G
|
T
|
C
|
G
|
C
|
T
|
A
|
A
|
G
|
C
|
C
|
T
|
C
|
C
|
A
|
G
|
C
|
A
|
G
|
G
|
T
|
A
|
G
|
C
|
G
|
A
|
T
|
T
|
C
|
C
|
T
|
A
|
G
|
C
|
A
|
C
|
C
|
A
|
T
|
G
|
G
|
A
|
T
|
C
|
G
|
C
|
T
|
T
|
A
|
G
|
C
|
T
|
G
|
C
|
G
|
T/C
|
T
|
T
|
A
|
G
|
C
|
G
|
G
|
C
|
T
|
C
|
T
|
G
|
G
|
T
|
G
|
C
|
A
|
C
|
C
|
A
|
T
|
|