|
.0 |
.0 |
.185 |
.009 |
1.0 |
.001 |
.0 |
.022 |
.021 |
.014 |
.006 |
.004 |
.001 |
.009 |
.468 |
.733 |
.795 |
.0 |
.006 |
.0 |
.002 |
.001 |
.004 |
.0 |
.011 |
.024 |
.293 |
.117 |
.002 |
.123 |
.014 |
.003 |
.01 |
.008 |
.003 |
.003 |
.0 |
.002 |
.0 |
.006 |
.001 |
.002 |
.003 |
.0 |
.0 |
.069 |
.003 |
.018 |
.017 |
.003 |
.017 |
.002 |
.384 |
.422 |
.992 |
.0 |
.001 |
.006 |
.001 |
.048 |
.005 |
.011 |
.054 |
.063 |
.033 |
.014 |
.226 |
.147 |
.32 |
.494 |
.001 |
.0 |
.143 |
.001 |
.004 |
.049 |
.079 |
.084 |
.045 |
.006 |
.02 |
.001 |
.0 |
.007 |
.186 |
.045 |
.041 |
.022 |
.023 |
.053 |
.036 |
.005 |
.0 |
.012 |
.001 |
.002 |
.002 |
.002 |
.0 |
.002 |
.0 |
.002 |
.97 |
.003 |
.003 |
.213 |
.029 |
.035 |
.015 |
.018 |
.003 |
.019 |
.002 |
.0 |
.0 |
.001 |
.001 |
.005 |
.019 |
.006 |
.003 |
.001 |
.001 |
.007 |
.011 |
.009 |
.002 |
.002 |
.015 |
.004 |
.008 |
.0 |
.016 |
.002 |
.016 |
.011 |
.005 |
.007 |
.257 |
.178 |
-- |
-- |
-- |
.003 |
.012 |
.004 |
.005 |
.003 |
.009 |
.001 |
.06 |
.07 |
.008 |
.031 |
.071 |
.093 |
.006 |
.017 |
.043 |
.057 |
.0 |
.008 |
.003 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
.009 |
.089 |
.002 |
.012 |
.022 |
.003 |
.0 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
.626 |
.662 |
.0 |
.0 |
.013 |
.001 |
.0 |
.026 |
.006 |
-- |
-- |
-- |
-- |
-- |
-- |
.001 |
.003 |
.017 |
.2 |
.007 |
.007 |
.001 |
.137 |
.034 |
.002 |
.025 |
.007 |
.293 |
.003 |
.006 |
.016 |
.046 |
.022 |
.032 |
.037 |
.041 |
.001 |
.0 |
.001 |
.0 |
.003 |
-- |
-- |
-- |
.002 |
.07 |
.029 |
.002 |
.976 |
.474 |
.002 |
.0 |
.0 |
.013 |
.001 |
.0 |
.027 |
.012 |
.178 |
.022 |
.035 |
.023 |
.246 |
.031 |
.0 |
.0 |
.004 |
.0 |
.173 |
.0 |
.001 |
.001 |
.494 |
.001 |
.0 |
.006 |
.002 |
.004 |
.002 |
.073 |
.012 |
.01 |
-- |
.006 |
.113 |
.015 |
.004 |
.001 |
.008 |
.003 |
.001 |
.001 |
.089 |
.051 |
.113 |
.149 |
.055 |
.045 |
.066 |
.004 |
.001 |
.002 |
.005 |
.024 |
.036 |
.037 |
.026 |
.001 |
.0 |
.111 |
.004 |
.357 |
.254 |
.458 |
.379 |
.141 |
.031 |
.034 |
.008 |
.008 |
.01 |
.067 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
.001 |
.072 |
.085 |
.007 |
.004 |
.008 |
.597 |
.013 |
.017 |
.164 |
.013 |
.006 |
.0 |
.07 |
.001 |
.001 |
.005 |
.244 |
.386 |
.002 |
.001 |
.011 |
.01 |
.0 |
.001 |
.025 |
.004 |
.024 |
.023 |
.0 |
.003 |
.0 |
.0 |
.004 |
.016 |
.001 |
.014 |
.003 |
.011 |
.003 |
.03 |
.108 |
.05 |
.026 |
.065 |
.048 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
.026 |
.033 |
-- |
.001 |
-- |
-- |
-- |
.008 |
.0 |
.01 |
.005 |
.627 |
.0 |
.0 |
.002 |
.001 |
.0 |
.011 |
.0 |
.051 |
-- |
-- |
.075 |
.055 |
.004 |
.001 |
.001 |
.002 |
.001 |
.002 |
.157 |
.01 |
.132 |
.0 |
.506 |
-- |
-- |
-- |
-- |
-- |
.0 |
.004 |
.002 |
.0 |
.081 |
|
Nox4
|
Nox4
|
Nox4
|
Nox4
|
Nox4
|
Nox4
|
Nox4
|
Nox4
|
Nox4
|
Nox4
|
Nox4
|
Nox4
|
Nox4
|
Nox4
|
Nox4
|
Nox4
|
Nox4
|
Nox4
|
Nox4
|
Nox4
|
Nox4
|
Nox4
|
Nox4
|
Nox4
|
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|
Nox4
|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
Nox4
|
Nox4
|
Nox4
|
Nox4
|
Nox4
|
Nox4
|
Nox4
|
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|
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|
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|
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|
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|
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--
|
--
|
--
|
--
|
--
|
--
|
--
|
|
T |
G |
T |
C |
- |
- |
C |
A |
A |
A |
C |
C |
G |
C |
T |
- |
5 |
T |
G |
- |
- |
A |
- |
G |
A |
T |
A |
T |
G |
A |
T |
A |
T |
C |
A |
T |
G |
C |
C |
T |
A |
G |
T |
A |
G |
G |
2 |
G |
- |
- |
T |
A |
A |
G |
- |
C |
T |
A |
G |
T |
C |
- |
A |
- |
T |
T |
A |
T |
T |
T |
T |
- |
T |
C |
C |
T |
- |
- |
A |
T |
T |
T |
A |
- |
G |
C |
- |
- |
C |
- |
- |
C |
G |
- |
G |
T |
C |
C |
C |
C |
- |
T |
C |
A |
- |
- |
3 |
4 |
3 |
7 |
G |
G |
T |
G |
A |
T |
T |
T |
T |
- |
C |
C |
C |
C |
- |
- |
G |
T |
A |
- |
A |
G |
T |
T |
- |
C |
T |
G |
G |
G |
G |
C |
C |
G |
G |
- |
C |
A |
G |
C |
- |
A |
C |
T |
- |
G |
- |
3 |
A |
A |
T |
T |
T |
A |
A |
5 |
G |
T |
- |
T |
G |
G |
- |
T |
G |
C |
G |
C |
G |
C |
C |
- |
A |
A |
T |
C |
T |
T |
A |
A |
- |
T |
C |
G |
A |
T |
G |
- |
- |
- |
13 |
T |
G |
G |
C |
C |
A |
T |
- |
A |
A |
T |
A |
G |
- |
A |
G |
C |
T |
A |
G |
- |
C |
C |
T |
C |
C |
- |
A |
A |
2 |
C |
C |
C |
2 |
T |
T |
G |
C |
A |
- |
- |
G |
- |
12 |
4 |
T |
- |
4 |
T |
C |
C |
T |
T |
23 |
T |
- |
C |
C |
G |
A |
A |
A |
C |
A |
T |
T |
- |
C |
T |
C |
A |
G |
G |
G |
T |
C |
- |
- |
A |
- |
A |
T |
A |
- |
G |
A |
A |
G |
A |
C |
3 |
- |
- |
A |
C |
T |
3 |
C |
C |
G |
C |
C |
A |
T |
- |
T |
- |
T |
2 |
- |
- |
- |
T |
- |
- |
C |
A |
A |
A |
C |
T |
C |
G |
C |
C |
A |
T |
A |
G |
- |
C |
G |
T |
G |
C |
C |
C |
G |
G |
5 |
10 |
G |
G |
C |
A |
C |
C |
G |
A |
A |
C |
A |
G |
G |
C |
T |
- |
G |
- |
T |
A |
A |
A |
C |
A |
A |
G |
A |
G |
G |
A |
T |
- |
T |
T |
T |
G |
C |
G |
C |
T |
G |
- |
G |
A |
C |
T |
A |
A |
A |
- |
A |
T |
12 |
T |
A |
G |
G |
C |
T |
C |
T |
T |
T |
G |
T |
T |
A |
G |
T |
G |
A |
C |
G |
T |
- |
G |
A |
A |
T |
- |
24 |
G |
C |
A |
A |
A |
A |
A |
A |
C |
A |
C |
A |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
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|
|
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|
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|
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|
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|
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|
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|
|
|
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|
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|
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|
|
|
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|
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|
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|
|
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|
|
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|
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|
|
|
|
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|
|
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|
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|
|
|
|
|
|
|
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|
|
|
|
|
|
|
|
|
|
|
|
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|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
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|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
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|
|
|
|
|
|
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|
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|
|
|
|
|
|
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|
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|
|
|
|
|
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|
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|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
C
|
C
|
C
|
T
|
G
|
T
|
-
|
A/T
|
A/T
|
A/T
|
C/T
|
T
|
A
|
T
|
C
|
-/T
|
5/-
|
C
|
A
|
3
|
T
|
G
|
8
|
T
|
C
|
C
|
G
|
-
|
T
|
G
|
A
|
G
|
G
|
T
|
C
|
C
|
A
|
A
|
T
|
C
|
G
|
A
|
C
|
G
|
A
|
T
|
-
|
T
|
4
|
17
|
C
|
C
|
G
|
A
|
A
|
G
|
-
|
G
|
A
|
C
|
A
|
A
|
G
|
G
|
C
|
A
|
-
|
C
|
-
|
A
|
C
|
13
|
C
|
G
|
T
|
A
|
8
|
3
|
T
|
C
|
-
|
C
|
G
|
A
|
-
|
T
|
3
|
C
|
-
|
A
|
A
|
-
|
-
|
T
|
-
|
-
|
T
|
T
|
-
|
-
|
T
|
A
|
G
|
G
|
G
|
T/G
|
-
|
-
|
-
|
-
|
A
|
A
|
G
|
A
|
T
|
-
|
G
|
-
|
C
|
50
|
A
|
T
|
T
|
A
|
T
|
T
|
A
|
C
|
G
|
3
|
-
|
A
|
C
|
C
|
T
|
A
|
C
|
C
|
-
|
C
|
A
|
T
|
A
|
A
|
A
|
2
|
T
|
G
|
A
|
T
|
G
|
T
|
T
|
C
|
A
|
A
|
A
|
-
|
G
|
-
|
C
|
A
|
-
|
C
|
G
|
5/-
|
T
|
G
|
G
|
G
|
A
|
T
|
A
|
G
|
T
|
G
|
A
|
T
|
C
|
A
|
T
|
A
|
C
|
C
|
C
|
T
|
C
|
C
|
T
|
T
|
T
|
C
|
A
|
C
|
G
|
G
|
A
|
G
|
A
|
A
|
-
|
G
|
A
|
A
|
G
|
T
|
T
|
C
|
8
|
G
|
C
|
C
|
G
|
C
|
T
|
T
|
A
|
T
|
G
|
G
|
C
|
-/A
|
T
|
A
|
G
|
T
|
T
|
9
|
C
|
-
|
-
|
T
|
T
|
T
|
-
|
C
|
A
|
C
|
T
|
G
|
2
|
2
|
C
|
2
|
-
|
-
|
C
|
A
|
-
|
C
|
A
|
T
|
-
|
C
|
-
|
C
|
T
|
T
|
T
|
A
|
G
|
-
|
G
|
G
|
C
|
-
|
C/A
|
8
|
T
|
C
|
T/G
|
G
|
C
|
A
|
A
|
C
|
T
|
A
|
A
|
-
|
T
|
-
|
-
|
C
|
C
|
-
|
-
|
-
|
A
|
G
|
T
|
-
|
A
|
A
|
-
|
-
|
-
|
-
|
-
|
-
|
-
|
-
|
-
|
-
|
G
|
T
|
C
|
3
|
G
|
-
|
C/C
|
T
|
G
|
-
|
T
|
A
|
A
|
C
|
C
|
-
|
-
|
C
|
T
|
A
|
A
|
G
|
C
|
G
|
G
|
C
|
A
|
A
|
A
|
C
|
A
|
G
|
A
|
G
|
A
|
T
|
-
|
10/-
|
C
|
C
|
T
|
G
|
A
|
T
|
C
|
C
|
G
|
T
|
G
|
T
|
A
|
T
|
A
|
A
|
A
|
A
|
A
|
T
|
C
|
C
|
T
|
G
|
T
|
A
|
G
|
A
|
T
|
C
|
T/A
|
-/T
|
T/C
|
A
|
T/C
|
C
|
C/A
|
G/T
|
C/G
|
G
|
G/C
|
A
|
G/A
|
T
|
-
|
C
|
-
|
-
|
G
|
4
|
C
|
A
|
-
|
-
|
C
|
A
|
A
|
T
|
C
|
T
|
G
|
C
|
C
|
T
|
A
|
C
|
G
|
A
|
C
|
A
|
G
|
T
|
T
|
A
|
4
|
A
|
G
|
T
|
A
|
C
|
-
|
A
|
T
|
G
|
G
|
G
|
G
|
G
|
G
|
T
|
G
|
T
|
C
|
|