|
.002 |
.0 |
.003 |
.037 |
.001 |
.002 |
.0 |
.0 |
.05 |
.001 |
.001 |
.0 |
.001 |
.0 |
.024 |
.0 |
.0 |
.0 |
.002 |
.0 |
.035 |
.002 |
.975 |
.002 |
.004 |
.004 |
.0 |
.0 |
.014 |
.0 |
.0 |
.0 |
.0 |
.0 |
.0 |
.0 |
.0 |
.0 |
.0 |
.0 |
.002 |
.0 |
.0 |
.002 |
.011 |
.0 |
.001 |
.565 |
.0 |
.019 |
.273 |
.006 |
.001 |
.005 |
.003 |
.001 |
.367 |
.391 |
.002 |
.008 |
.032 |
.005 |
.0 |
.0 |
.843 |
.002 |
.008 |
.011 |
.004 |
.0 |
.685 |
.002 |
.45 |
.169 |
.1 |
.136 |
.139 |
.141 |
.136 |
.026 |
.004 |
.001 |
.0 |
.995 |
.001 |
.012 |
.988 |
.039 |
.007 |
.02 |
.004 |
.004 |
.0 |
.015 |
.001 |
.0 |
.005 |
.003 |
.018 |
.0 |
.043 |
.076 |
.0 |
.0 |
.001 |
.0 |
.002 |
.025 |
.004 |
.003 |
-- |
.043 |
.048 |
.014 |
.032 |
.041 |
.081 |
.037 |
.024 |
.004 |
.171 |
.014 |
-- |
-- |
-- |
-- |
.29 |
.001 |
.0 |
.001 |
.009 |
.0 |
.013 |
.005 |
.006 |
.0 |
.01 |
.002 |
.009 |
.001 |
.0 |
.033 |
.419 |
.0 |
.0 |
.0 |
.001 |
.002 |
.026 |
.0 |
.038 |
.014 |
.01 |
.005 |
.154 |
.124 |
.024 |
.994 |
.96 |
.0 |
.0 |
.001 |
.004 |
.225 |
.601 |
.001 |
.002 |
.001 |
.0 |
.051 |
.0 |
.0 |
.002 |
.096 |
.003 |
.001 |
.002 |
.086 |
.0 |
.0 |
.005 |
.128 |
.0 |
.002 |
.0 |
.001 |
.004 |
.001 |
.0 |
.004 |
.004 |
.042 |
.008 |
.001 |
.151 |
.0 |
.007 |
.003 |
.001 |
.0 |
.001 |
.0 |
.0 |
.0 |
.0 |
.011 |
.007 |
.0 |
.001 |
.002 |
-- |
.0 |
.0 |
.001 |
.001 |
.268 |
.001 |
.002 |
.001 |
.001 |
.0 |
.0 |
.064 |
.002 |
.001 |
.007 |
.016 |
.017 |
.017 |
.013 |
.0 |
.853 |
.0 |
.001 |
.756 |
.012 |
.005 |
.008 |
.001 |
.001 |
.0 |
.003 |
.005 |
.002 |
.007 |
.621 |
.002 |
.004 |
.003 |
.001 |
.001 |
.002 |
.06 |
.03 |
.009 |
1.0 |
.038 |
.019 |
.001 |
.0 |
.068 |
.001 |
.771 |
.002 |
.002 |
.0 |
.0 |
.0 |
.0 |
.0 |
.005 |
.483 |
.54 |
.07 |
.01 |
.089 |
.01 |
.0 |
.001 |
.0 |
.017 |
.644 |
|
Mrc1
|
Mrc1
|
Mrc1
|
Mrc1
|
Mrc1
|
Mrc1
|
Mrc1
|
Mrc1
|
Mrc1
|
Mrc1
|
Mrc1
|
Mrc1
|
Mrc1
|
Mrc1
|
Mrc1
|
Mrc1
|
Mrc1
|
Mrc1
|
Mrc1
|
Mrc1
|
Mrc1
|
Mrc1
|
Mrc1
|
Mrc1
|
Mrc1
|
Mrc1
|
Mrc1
|
Mrc1
|
Mrc1
|
|
--
|
--
|
--
|
--
|
--
|
--
|
--
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--
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--
|
--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
|
--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
|
--
|
--
|
--
|
--
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--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
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--
|
--
|
--
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--
|
--
|
--
|
--
|
--
|
--
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--
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--
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--
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--
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--
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--
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--
|
--
|
--
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--
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--
|
--
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--
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--
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--
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--
|
--
|
--
|
--
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--
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--
|
--
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--
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--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
|
G |
G |
A |
38 |
C |
T |
T |
G |
T |
C |
T |
T |
G |
G |
G |
A |
T |
G |
A |
T |
A |
- |
G |
G |
C |
C |
T |
A |
A |
G |
A |
T |
G |
C |
- |
A |
T |
T |
G |
T |
C |
T |
A |
A |
T |
- |
4 |
T |
A |
T |
A |
G |
C |
G |
C |
A |
A |
T |
T |
A |
G |
C |
- |
A |
T |
- |
T |
C |
C |
A |
G |
T |
A |
A |
2 |
- |
T |
G |
7 |
A |
A |
G |
G |
A |
C |
4 |
- |
T |
- |
A |
5 |
A |
C |
A |
T |
G |
A |
C |
- |
C |
A |
T |
A |
C |
6 |
C |
A |
A |
A |
38 |
28 |
C |
T |
T |
C |
C |
A |
- |
T |
T |
C |
G |
C |
C |
T |
A |
C |
G |
C |
C |
A |
T |
G |
C |
C |
T |
A |
22 |
A |
A |
A |
A |
A |
A |
C |
G |
T |
T |
C |
- |
A |
T |
G |
T |
C |
T |
G |
T |
T |
A |
C |
T |
A |
G |
G |
G |
C |
A |
T |
G |
T |
G |
A |
T |
G |
C |
T |
G |
G |
T |
T |
T |
C |
T |
C |
T |
A |
- |
C |
G |
A |
C |
- |
C |
2 |
G |
G |
T |
A |
G |
G |
G |
G |
C |
C |
T |
T |
G |
A |
A |
A |
C |
C |
A |
A |
C |
T |
A |
A |
G |
C |
T |
T |
A |
G |
G |
T |
C |
T |
3 |
C |
G |
C |
C |
T |
C |
T |
C |
A |
A |
C |
A |
- |
A |
- |
C |
A |
G |
G |
A |
C |
A |
- |
T |
T |
C |
C |
A |
A |
C |
C |
A |
G |
G |
T |
A |
4 |
C |
A |
C |
T |
T |
G |
G |
2 |
22 |
- |
G |
T |
G |
2 |
C |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
A
|
A
|
G
|
-
|
T
|
C
|
-
|
A
|
C
|
T
|
G
|
C
|
A
|
T
|
A
|
C
|
G
|
T
|
C
|
C
|
G
|
4
|
A
|
A
|
T
|
T
|
C
|
G
|
G
|
A
|
T
|
C
|
A
|
T
|
4
|
C
|
A
|
C
|
T
|
C
|
A
|
-
|
T
|
G
|
C
|
T
|
-
|
C
|
G
|
C
|
G
|
A
|
T
|
A
|
A
|
C
|
C
|
A
|
C
|
C
|
C
|
T
|
8
|
C
|
-
|
4
|
C
|
-
|
T
|
G
|
A
|
C
|
G
|
G
|
-
|
C
|
-
|
T
|
-
|
G
|
C
|
C
|
C
|
G
|
T
|
-
|
-/8
|
A
|
A
|
G
|
-
|
G
|
T
|
G
|
G
|
T
|
-
|
T
|
10/C
|
A
|
G
|
C
|
C
|
T
|
-
|
T
|
T
|
C
|
G
|
38/-
|
-
|
T
|
C
|
A
|
T
|
T
|
G
|
T
|
C
|
C
|
G
|
A
|
T
|
T
|
C
|
G
|
T
|
T
|
T
|
G
|
G
|
C
|
C
|
T
|
-
|
C
|
T
|
-
|
G
|
T
|
T
|
-
|
T
|
G
|
T
|
A
|
C
|
C
|
A
|
A
|
C
|
C
|
A
|
C
|
T
|
C
|
A
|
C
|
C
|
G
|
T
|
-
|
G
|
A
|
A
|
A
|
T
|
G
|
C
|
T
|
C
|
A
|
G
|
C
|
A
|
T
|
A
|
-
|
A
|
C
|
C
|
C
|
T
|
C
|
T
|
C
|
G
|
2
|
G
|
T
|
G
|
T
|
2
|
T
|
-
|
A
|
A
|
C
|
G
|
A
|
T
|
C
|
T
|
A
|
T
|
C
|
C
|
A
|
G
|
G
|
C
|
T
|
T
|
G
|
C
|
T
|
C
|
G
|
G
|
A
|
T
|
C
|
G
|
G
|
A
|
A
|
A
|
-
|
A
|
-
|
G
|
A
|
T
|
T
|
C
|
T
|
C
|
T
|
T
|
T
|
T
|
T
|
A
|
G
|
2
|
T
|
G
|
A
|
C
|
C
|
T
|
T
|
T
|
-
|
-
|
T
|
T
|
G
|
G
|
T
|
A
|
G
|
A
|
T
|
G
|
G
|
-
|
T
|
G
|
T
|
C
|
A
|
A
|
C
|
-
|
22/-
|
C
|
A
|
C
|
C
|
-
|
T
|
|