|
.0 |
.0 |
.971 |
.0 |
.357 |
.007 |
.049 |
.446 |
.007 |
.0 |
.004 |
.044 |
.003 |
.001 |
.001 |
.029 |
.046 |
.184 |
.001 |
.363 |
.0 |
.006 |
.055 |
.0 |
.191 |
.0 |
.004 |
.0 |
.001 |
.015 |
.0 |
.002 |
.002 |
.002 |
.104 |
.875 |
.338 |
.029 |
.004 |
.003 |
.013 |
1.0 |
1.0 |
1.0 |
.919 |
.005 |
.005 |
.014 |
.006 |
.055 |
.001 |
.002 |
.0 |
.032 |
.002 |
.135 |
.0 |
-- |
.012 |
.08 |
-- |
-- |
.824 |
.004 |
.0 |
.0 |
.001 |
.001 |
.001 |
.002 |
.0 |
.001 |
.047 |
.779 |
.0 |
.0 |
.002 |
.003 |
.068 |
.002 |
.0 |
.0 |
.001 |
.0 |
.424 |
.002 |
.016 |
.007 |
.043 |
.149 |
.008 |
.002 |
.002 |
.024 |
.494 |
.15 |
.006 |
.003 |
.147 |
.005 |
.017 |
.016 |
.005 |
.043 |
.023 |
.139 |
.092 |
.103 |
.062 |
.1 |
.026 |
-- |
.001 |
.035 |
.126 |
.003 |
.003 |
.0 |
.0 |
.002 |
.012 |
.001 |
.002 |
.01 |
.956 |
.913 |
.002 |
.003 |
.0 |
.0 |
.0 |
.032 |
.025 |
.002 |
.002 |
.002 |
.022 |
.001 |
.903 |
.944 |
.001 |
.0 |
.0 |
.021 |
.0 |
.401 |
.0 |
.015 |
.003 |
.0 |
.0 |
.0 |
.0 |
.001 |
.388 |
.001 |
.001 |
-- |
-- |
-- |
-- |
.007 |
.0 |
.006 |
.008 |
.092 |
.0 |
.002 |
.053 |
.0 |
.002 |
.018 |
.066 |
.003 |
.006 |
.011 |
.0 |
.744 |
.006 |
.0 |
.085 |
.0 |
.0 |
.0 |
.013 |
.005 |
.016 |
.0 |
.01 |
.001 |
.082 |
.001 |
.001 |
.025 |
.001 |
.0 |
.0 |
.001 |
.051 |
.123 |
.012 |
.055 |
.001 |
.005 |
.0 |
.002 |
.034 |
.024 |
.0 |
.0 |
.025 |
.908 |
.0 |
-- |
-- |
.039 |
.0 |
.0 |
.023 |
.001 |
.011 |
.005 |
.0 |
.003 |
.002 |
.0 |
.102 |
.0 |
.23 |
.096 |
.0 |
.004 |
.001 |
.042 |
.067 |
.001 |
.024 |
.003 |
.005 |
.0 |
.273 |
.0 |
.0 |
.0 |
.033 |
.01 |
.034 |
.005 |
.016 |
.001 |
.006 |
.013 |
.785 |
.003 |
.003 |
.007 |
.063 |
.013 |
.0 |
.016 |
.024 |
.011 |
.006 |
.001 |
.002 |
.005 |
.056 |
.004 |
.004 |
.002 |
.001 |
.015 |
.011 |
.002 |
.0 |
.089 |
.125 |
.001 |
.001 |
.001 |
.208 |
.972 |
.954 |
.923 |
.826 |
.838 |
-- |
.0 |
.0 |
.007 |
.001 |
.0 |
.005 |
.001 |
.001 |
.001 |
.007 |
.01 |
.005 |
.021 |
.012 |
.065 |
.001 |
.049 |
.162 |
.205 |
.541 |
.525 |
.004 |
.029 |
.058 |
.015 |
.008 |
.001 |
.258 |
.004 |
.006 |
.023 |
.008 |
.002 |
.0 |
.02 |
.012 |
.018 |
.083 |
.004 |
.002 |
.004 |
.001 |
.008 |
.117 |
.026 |
.057 |
.012 |
.01 |
.008 |
.034 |
.02 |
.001 |
.004 |
.001 |
.001 |
.014 |
.0 |
.012 |
.0 |
.005 |
.047 |
.0 |
.003 |
.001 |
.001 |
.047 |
.021 |
.016 |
.0 |
.005 |
.001 |
.0 |
.007 |
.007 |
.0 |
.007 |
.001 |
.016 |
.004 |
.002 |
.373 |
.017 |
.0 |
.012 |
.0 |
.002 |
.039 |
.001 |
.003 |
.004 |
.0 |
.004 |
.052 |
.022 |
.083 |
.009 |
.934 |
.004 |
.993 |
.001 |
.59 |
.0 |
.002 |
.006 |
.001 |
.119 |
.005 |
.012 |
.001 |
.0 |
.0 |
.001 |
.376 |
.005 |
.007 |
.004 |
.007 |
.999 |
.003 |
.001 |
.005 |
-- |
.956 |
.974 |
.978 |
.001 |
.0 |
.002 |
.001 |
.004 |
.265 |
.029 |
.11 |
.0 |
.0 |
.002 |
.0 |
.0 |
.001 |
.008 |
.0 |
.0 |
.0 |
.001 |
.008 |
-- |
-- |
.003 |
.002 |
.009 |
.069 |
.002 |
.004 |
.022 |
.002 |
.009 |
.005 |
.097 |
.044 |
.002 |
.001 |
.0 |
.0 |
.005 |
.001 |
.001 |
.002 |
.0 |
.011 |
.0 |
.02 |
.014 |
.003 |
.135 |
.0 |
.003 |
.003 |
.355 |
.0 |
.681 |
.006 |
.009 |
.001 |
.062 |
.0 |
.036 |
.0 |
.001 |
.005 |
.0 |
.0 |
.014 |
.009 |
.001 |
.002 |
.0 |
.005 |
.165 |
.165 |
.0 |
.0 |
.046 |
.0 |
.002 |
.002 |
.0 |
.005 |
.003 |
.003 |
.004 |
.001 |
.002 |
.006 |
.004 |
.006 |
.029 |
.143 |
.135 |
.005 |
.0 |
.04 |
.141 |
.97 |
.062 |
.002 |
.022 |
.005 |
.094 |
.009 |
.026 |
-- |
-- |
.011 |
-- |
-- |
-- |
.001 |
.001 |
.028 |
.165 |
.027 |
1.0 |
.127 |
.355 |
.901 |
.973 |
.001 |
.0 |
1.0 |
.0 |
.001 |
.001 |
.001 |
.0 |
.0 |
.0 |
.059 |
.0 |
.005 |
.006 |
.07 |
.577 |
.014 |
.008 |
.003 |
.689 |
.025 |
.055 |
.0 |
.002 |
.0 |
.001 |
.0 |
.0 |
.0 |
.002 |
.181 |
.0 |
.998 |
.998 |
.269 |
.0 |
.0 |
.0 |
.021 |
.004 |
.0 |
.003 |
.004 |
.003 |
.012 |
-- |
.002 |
.003 |
.084 |
.0 |
.2 |
.389 |
.999 |
.995 |
.784 |
.575 |
.613 |
.011 |
.001 |
.003 |
.0 |
.001 |
.001 |
.0 |
.011 |
.014 |
.008 |
.068 |
.003 |
.126 |
.027 |
.002 |
.0 |
.007 |
.146 |
.001 |
.004 |
.001 |
.004 |
.003 |
.019 |
-- |
-- |
-- |
-- |
-- |
.001 |
.0 |
.002 |
.001 |
.007 |
.02 |
.01 |
.026 |
.003 |
.003 |
.025 |
.027 |
.039 |
.22 |
.006 |
.028 |
.026 |
.015 |
.003 |
.015 |
.004 |
.0 |
.0 |
.001 |
.0 |
.003 |
.001 |
.004 |
.0 |
.0 |
-- |
-- |
-- |
-- |
-- |
.041 |
.005 |
.006 |
.023 |
.013 |
.0 |
.004 |
.001 |
.002 |
.099 |
.001 |
.0 |
.003 |
.0 |
.002 |
.0 |
.0 |
.0 |
.011 |
.0 |
.0 |
.01 |
.0 |
.001 |
.002 |
.004 |
.0 |
.017 |
.008 |
.007 |
.042 |
.005 |
.006 |
.014 |
.022 |
.077 |
.05 |
.219 |
.238 |
.092 |
.007 |
.007 |
.009 |
.03 |
.024 |
.016 |
.013 |
.065 |
.078 |
.14 |
.125 |
.038 |
-- |
-- |
-- |
-- |
-- |
-- |
.013 |
.004 |
.04 |
.0 |
.0 |
.673 |
.004 |
.0 |
.0 |
.0 |
.049 |
.002 |
.041 |
.024 |
.003 |
.0 |
1.0 |
.268 |
.0 |
.0 |
.026 |
.001 |
.016 |
.002 |
-- |
.0 |
.007 |
.0 |
.1 |
.101 |
.001 |
.719 |
.001 |
.001 |
.209 |
.104 |
.0 |
.581 |
.0 |
.0 |
.002 |
.216 |
.012 |
.0 |
.001 |
.667 |
.0 |
.008 |
.0 |
.0 |
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
|
A |
G |
T |
T |
T |
C |
T |
T |
G |
T |
G |
A |
C |
C |
C |
T |
A |
G |
T |
C |
G |
T |
G |
G |
G |
T |
C |
G |
T |
C |
T |
G |
T |
C |
G |
T |
A |
C |
G |
G |
G |
G |
C |
T |
G |
G |
G |
A |
G |
C |
T |
G |
T |
C |
G |
A |
C |
G |
G |
T |
G |
T |
G |
T |
A |
T |
A |
A |
T |
A |
C |
C |
C |
A |
C |
C |
A |
C |
C |
G |
A |
T |
C |
C |
A |
T |
A |
C |
A |
T |
A |
T |
C |
A |
T |
C |
C |
C |
A |
T |
T |
T |
A |
G |
C |
T |
T |
A |
C |
G |
C |
A |
G |
G |
G |
T |
C |
T |
G |
G |
A |
C |
C |
C |
C |
G |
C |
C |
G |
G |
C |
A |
C |
C |
G |
C |
A |
A |
T |
T |
A |
C |
C |
T |
C |
A |
C |
G |
T |
A |
G |
A |
T |
T |
A |
C |
A |
C |
A |
T |
C |
T |
C |
T |
C |
A |
C |
T |
T |
A |
C |
C |
C |
A |
T |
G |
G |
T |
T |
G |
G |
T |
G |
C |
G |
G |
G |
A |
C |
T |
C |
C |
T |
G |
T |
T |
T |
T |
G |
T |
C |
C |
A |
A |
T |
T |
T |
G |
C |
T |
T |
G |
A |
A |
T |
G |
G |
G |
G |
T |
G |
G |
T |
G |
C |
T |
A |
C |
A |
A |
A |
G |
T |
A |
T |
G |
C |
G |
A |
T |
A |
A |
G |
A |
G |
A |
G |
T |
T |
G |
G |
A |
T |
G |
C |
C |
G |
G |
C |
C |
T |
A |
A |
C |
C |
T |
G |
A |
A |
T |
T |
A |
C |
T |
G |
A |
G |
C |
C |
A |
T |
T |
T |
G |
A |
A |
T |
A |
C |
G |
C |
A |
T |
T |
G |
A |
A |
G |
T |
A |
A |
T |
G |
A |
G |
T |
C |
A |
C |
A |
T |
C |
A |
T |
C |
T |
A |
T |
T |
T |
A |
A |
G |
T |
C |
A |
G |
A |
C |
T |
T |
T |
G |
A |
G |
G |
T |
G |
G |
A |
C |
G |
C |
C |
C |
G |
A |
T |
A |
C |
C |
T |
G |
C |
T |
G |
C |
T |
A |
T |
T |
G |
A |
G |
A |
A |
T |
G |
G |
G |
T |
T |
C |
T |
A |
T |
A |
G |
C |
A |
A |
C |
T |
T |
C |
T |
T |
C |
G |
C |
C |
C |
T |
A |
C |
A |
C |
G |
T |
C |
A |
G |
T |
G |
G |
C |
T |
A |
G |
C |
G |
G |
T |
G |
T |
G |
T |
T |
T |
A |
T |
T |
A |
C |
T |
A |
A |
G |
A |
G |
C |
A |
A |
A |
C |
C |
C |
G |
T |
C |
T |
A |
A |
T |
G |
T |
A |
A |
C |
T |
G |
C |
A |
T |
G |
A |
T |
A |
G |
G |
G |
A |
T |
G |
G |
A |
T |
C |
G |
C |
C |
G |
T |
C |
A |
C |
C |
A |
T |
G |
T |
C |
G |
T |
C |
G |
T |
C |
T |
C |
A |
G |
C |
C |
G |
G |
C |
G |
C |
A |
T |
C |
A |
A |
A |
G |
T |
T |
A |
G |
A |
A |
G |
G |
T |
G |
C |
T |
A |
A |
A |
G |
T |
C |
C |
T |
G |
T |
T |
A |
G |
C |
A |
G |
G |
T |
T |
T |
C |
G |
T |
C |
T |
G |
T |
T |
T |
T |
A |
C |
T |
T |
C |
T |
T |
A |
T |
T |
A |
A |
T |
A |
C |
A |
T |
T |
A |
T |
A |
T |
C |
C |
C |
T |
T |
A |
G |
C |
A |
C |
C |
A |
C |
T |
T |
G |
T |
A |
C |
T |
A |
C |
G |
T |
A |
T |
A |
C |
G |
G |
T |
C |
A |
A |
T |
A |
T |
C |
A |
A |
C |
T |
A |
G |
A |
C |
T |
C |
A |
G |
G |
T |
A |
C |
T |
G |
T |
A |
T |
A |
A |
C |
C |
T |
A |
C |
C |
G |
G |
G |
C |
T |
G |
C |
T |
T |
G |
A |
T |
C |
C |
C |
A |
C |
G |
C |
T |
C |
G |
A |
A |
G |
T |
A |
T |
T |
A |
C |
A |
G |
G |
T |
T |
A |
G |
A |
G |
A |
T |
A |
G |
T |
T |
G |
C |
G |
T |
G |
G |
C |
T |
G |
C |
C |
G |
T |
G |
G |
T |
A |
A |
C |
A |
T |
G |
G |
C |
T |
C |
C |
A |
A |
C |
T |
T |
C |
T |
A |
C |
T |
A |
A |
C |
A |
T |
C |
T |
T |
C |
T |
G |
C |
A |
C |
C |
T |
C |
T |
A |
C |
A |
G |
T |
C |
C |
G |
G |
G |
C |
T |
C |
T |
T |
G |
A |
C |
T |
T |
C |
T |
C |
T |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
A/G
|
A
|
C
|
C
|
C
|
T
|
C
|
T/C
|
A
|
C
|
A
|
G
|
T
|
T
|
T
|
C
|
C
|
A
|
T/G
|
T
|
A
|
C
|
A
|
T
|
A
|
A
|
A
|
A
|
C
|
T
|
G
|
A
|
C
|
T
|
A
|
T/A
|
G
|
T
|
A
|
A
|
A
|
A
|
T
|
G
|
A
|
C
|
A
|
G
|
A
|
T
|
G
|
A
|
C
|
T
|
T
|
C
|
T
|
G/A
|
A
|
C
|
G/A
|
T/C
|
A
|
C
|
G
|
C
|
T
|
G
|
C
|
G
|
T
|
T
|
A
|
G
|
G
|
G
|
C
|
T
|
A
|
A
|
G
|
C
|
A
|
T
|
G
|
C
|
G
|
T
|
C
|
C
|
T
|
C
|
T
|
T
|
C
|
T
|
A
|
T
|
G
|
A
|
G
|
A
|
C
|
T
|
G
|
C
|
G
|
G
|
T
|
A
|
T
|
G
|
A
|
A
|
G/A
|
G
|
T
|
C
|
A
|
T
|
G
|
T
|
A
|
T
|
T
|
C
|
T
|
A
|
C
|
A
|
A
|
G
|
T
|
T
|
A
|
T
|
G
|
C
|
T/G
|
T/C
|
T
|
C/T
|
T
|
C
|
T
|
A/T
|
T
|
A
|
C
|
G
|
T
|
T
|
C
|
C
|
C
|
T
|
G
|
T
|
G
|
T/C
|
C/T
|
C
|
T
|
G
|
T
|
T
|
T
|
C
|
C
|
G
|
T
|
T
|
T
|
G
|
A
|
C
|
A
|
C
|
C
|
A
|
A
|
C
|
T
|
T
|
C
|
C
|
T
|
C
|
T
|
A
|
T
|
G
|
G
|
A
|
C
|
C
|
G
|
C
|
T
|
C
|
A
|
A
|
G
|
C
|
G
|
G
|
C
|
A
|
T
|
C
|
C
|
A
|
G
|
G
|
C
|
T
|
C
|
A
|
C
|
C
|
A
|
A
|
C
|
A
|
T
|
G
|
G
|
T
|
G
|
T
|
G
|
A
|
C
|
G
|
C
|
C
|
T
|
A
|
G
|
C
|
G
|
G
|
C
|
G
|
A
|
A/C
|
C
|
C
|
G
|
A
|
A
|
G
|
C
|
A
|
T
|
T
|
A
|
A
|
T
|
A
|
C
|
G
|
T
|
A
|
T
|
C
|
A
|
G
|
T
|
C
|
A
|
G
|
G
|
C
|
A
|
T
|
A
|
T
|
T
|
G
|
C
|
A
|
G
|
C
|
G
|
G
|
C
|
G
|
T
|
A
|
T
|
G
|
G
|
A
|
A
|
T
|
G
|
A
|
C
|
G
|
G
|
A
|
C
|
G
|
A
|
G
|
T
|
G
|
A
|
G
|
C
|
T
|
C
|
G
|
T
|
C
|
G
|
C
|
C
|
C
|
G
|
G
|
A
|
A
|
T
|
T
|
A
|
T
|
T
|
C
|
C
|
C
|
A
|
G
|
T
|
C
|
C
|
A
|
A
|
G
|
T
|
A
|
T
|
T
|
A
|
T
|
C
|
C
|
G
|
A
|
T
|
C
|
T
|
A
|
C
|
A
|
T
|
C
|
G
|
C
|
A
|
A
|
G
|
A
|
T
|
C
|
A
|
C
|
G/A
|
A
|
C
|
G
|
T
|
C
|
G
|
C
|
C
|
A
|
T
|
C
|
G
|
T
|
C
|
A
|
A
|
A
|
G
|
T
|
A
|
T
|
G
|
T
|
C
|
G
|
T
|
G
|
T
|
T
|
C
|
T
|
G
|
T
|
C
|
A
|
T
|
G
|
C
|
T
|
T
|
C/G
|
C
|
C
|
C
|
A
|
G
|
G/A
|
G
|
C
|
C
|
G
|
C
|
C
|
G
|
T
|
A
|
G
|
C
|
A
|
T
|
A
|
T
|
G
|
A/C
|
A/G
|
T
|
A
|
T
|
A
|
A
|
T
|
A
|
G
|
G
|
C
|
A
|
C
|
T
|
G
|
T
|
C
|
A
|
T
|
G
|
A
|
A
|
G
|
A
|
G
|
A
|
A
|
A
|
G
|
C
|
A
|
A
|
G
|
A
|
T
|
A
|
T
|
T
|
A
|
C
|
A
|
G
|
T
|
T
|
G
|
C
|
A
|
G
|
G
|
C
|
G
|
A
|
A
|
C
|
T
|
C
|
T
|
C
|
T
|
T
|
T
|
C
|
A
|
T
|
A
|
A
|
G
|
C
|
G
|
G
|
G
|
T
|
A
|
C
|
C
|
T
|
A
|
G
|
T
|
A
|
T
|
G
|
A
|
T
|
A
|
T
|
A/T
|
A/C
|
G/A
|
C
|
T
|
G
|
C
|
A
|
C
|
G
|
T
|
A
|
T
|
T
|
T
|
C
|
C
|
C
|
C
|
A
|
A
|
A
|
T
|
C
|
A
|
G
|
C
|
C
|
C
|
T
|
T
|
C
|
C
|
T
|
G
|
G
|
A/G
|
C
|
G
|
G
|
G
|
G
|
T
|
T
|
G
|
G
|
C
|
T
|
A
|
C
|
C
|
T
|
T
|
T
|
A
|
C
|
G
|
A
|
G
|
G
|
T
|
T
|
A/G
|
G
|
C
|
C
|
A
|
C
|
G
|
G
|
C
|
G
|
T
|
A
|
G
|
T
|
C
|
G
|
T
|
A
|
T
|
C
|
T
|
G
|
G
|
C
|
T
|
C
|
T
|
G
|
C
|
T
|
C
|
C
|
A
|
T
|
T
|
C
|
T
|
G
|
A
|
A
|
C
|
G
|
G
|
G
|
A
|
C
|
T
|
C
|
G
|
G
|
T
|
T
|
A
|
G
|
T
|
T
|
A
|
A
|
A
|
T
|
C
|
A
|
T
|
G
|
G
|
A
|
T
|
C
|
G
|
T
|
A
|
G
|
T
|
A
|
T
|
C
|
A
|
A
|
G
|
G
|
A
|
C
|
G
|
C
|
C
|
C
|
T
|
G
|
C
|
A
|
C
|
G
|
C
|
A
|
G
|
T
|
G
|
C
|
G
|
A
|
C
|
C
|
C
|
T
|
A
|
C
|
T
|
A
|
T
|
C
|
C
|
T
|
G
|
A
|
C
|
A
|
C
|
C
|
G
|
T
|
T
|
G
|
C
|
A
|
T
|
T
|
C
|
T
|
T
|
G
|
G
|
T
|
C
|
G
|
T
|
C
|
C
|
T
|
C
|
G
|
G
|
T
|
G
|
A
|
G
|
C
|
C
|
T
|
C
|
A
|
T
|
G
|
T
|
T
|
C
|
A
|
C
|
G
|
A
|
A/G
|
G/A
|
C
|
T
|
T
|
A
|
A
|
A
|
A
|
A
|
T
|
A
|
C
|
C
|
G
|
T
|
C
|
G
|
T
|
T/A
|
T
|
G
|
|