|
.002 |
.049 |
.001 |
.001 |
.046 |
.082 |
.058 |
.0 |
.0 |
.001 |
.0 |
.0 |
.0 |
.006 |
.0 |
.009 |
.001 |
.03 |
.023 |
.191 |
.088 |
.0 |
.005 |
.0 |
.0 |
.004 |
.001 |
.01 |
.028 |
.46 |
.0 |
.007 |
.003 |
.176 |
.248 |
.266 |
.203 |
.0 |
.0 |
.0 |
.096 |
.001 |
.0 |
.0 |
.016 |
.001 |
.015 |
.005 |
.0 |
.002 |
.002 |
.002 |
.004 |
.048 |
.104 |
.939 |
.029 |
.004 |
.003 |
.013 |
1.0 |
1.0 |
1.0 |
1.0 |
.919 |
.465 |
.005 |
.003 |
.0 |
.005 |
.006 |
.055 |
.001 |
.002 |
.001 |
.001 |
.0 |
.005 |
.044 |
.004 |
.001 |
.0 |
.02 |
.011 |
.0 |
.066 |
.014 |
.0 |
.003 |
.472 |
.174 |
.092 |
.001 |
.004 |
.032 |
.019 |
.135 |
.006 |
.012 |
.016 |
.0 |
.08 |
.03 |
.143 |
.008 |
.002 |
.0 |
.001 |
.004 |
.024 |
.001 |
.017 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
.824 |
.024 |
.019 |
.0 |
.004 |
.0 |
.001 |
.001 |
.056 |
.002 |
.0 |
.001 |
.424 |
.002 |
.013 |
.259 |
.263 |
.005 |
.004 |
.176 |
.016 |
.001 |
.023 |
.139 |
.103 |
.012 |
.016 |
.062 |
.001 |
-- |
.011 |
.002 |
.031 |
.001 |
.126 |
.003 |
.003 |
.0 |
.0 |
.002 |
.012 |
.001 |
.002 |
.956 |
.913 |
.019 |
.0 |
.002 |
.002 |
.176 |
.01 |
.307 |
.001 |
.952 |
.002 |
.001 |
.0 |
.002 |
.0 |
.085 |
.019 |
.004 |
.002 |
.002 |
.084 |
.006 |
.026 |
.008 |
.01 |
.092 |
.0 |
.0 |
.005 |
.003 |
.001 |
.002 |
.053 |
.014 |
.0 |
.0 |
.002 |
.0 |
.012 |
.0 |
.005 |
.0 |
.0 |
.0 |
.0 |
.0 |
.0 |
.139 |
.976 |
.001 |
.002 |
.018 |
.004 |
.001 |
.004 |
.001 |
.0 |
.006 |
.0 |
.002 |
.01 |
.006 |
.744 |
.006 |
.0 |
.013 |
.085 |
.003 |
.0 |
.0 |
.0 |
.005 |
.016 |
.0 |
.01 |
.001 |
.082 |
.001 |
.001 |
.002 |
.0 |
.001 |
.0 |
.0 |
.0 |
.0 |
.001 |
.009 |
.0 |
.001 |
.001 |
.0 |
.0 |
.0 |
.001 |
.0 |
.0 |
.469 |
.001 |
.02 |
.003 |
.002 |
.0 |
.212 |
.051 |
.791 |
.001 |
.142 |
.008 |
.123 |
.007 |
.002 |
.0 |
.001 |
.246 |
.006 |
.0 |
.032 |
.058 |
.002 |
.001 |
.001 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
.012 |
.01 |
.001 |
.0 |
.006 |
.001 |
.364 |
.417 |
.001 |
.015 |
.004 |
.0 |
.007 |
.097 |
.006 |
.002 |
.0 |
.051 |
.115 |
.004 |
.0 |
.008 |
.19 |
.0 |
.005 |
.003 |
.005 |
.007 |
.001 |
.273 |
.024 |
.228 |
.007 |
.039 |
.0 |
.002 |
.0 |
.0 |
.0 |
.002 |
.004 |
.001 |
.004 |
.015 |
.042 |
.067 |
.003 |
.005 |
.0 |
.0 |
.273 |
.0 |
.0 |
.0 |
.033 |
.01 |
.034 |
.005 |
.016 |
.013 |
.001 |
.006 |
.013 |
.785 |
.0 |
.004 |
.063 |
.0 |
.016 |
.009 |
.007 |
.024 |
.011 |
.006 |
.0 |
.002 |
.005 |
.056 |
.004 |
.004 |
.002 |
.001 |
.015 |
.011 |
.004 |
.106 |
.07 |
.002 |
.051 |
.376 |
.002 |
.004 |
.003 |
.002 |
.0 |
.125 |
.004 |
.954 |
.923 |
.826 |
.838 |
.001 |
.0 |
.001 |
.011 |
-- |
-- |
-- |
.086 |
.002 |
.008 |
.001 |
.004 |
.009 |
.117 |
.026 |
.02 |
.0 |
.003 |
.026 |
.03 |
.653 |
.052 |
.05 |
.002 |
.003 |
.0 |
.001 |
.001 |
.002 |
.792 |
.901 |
.003 |
.012 |
.0 |
.002 |
.003 |
.091 |
.0 |
.006 |
.009 |
.0 |
.001 |
.0 |
-- |
.0 |
.474 |
.005 |
.001 |
.006 |
.001 |
.084 |
.006 |
.001 |
.006 |
.0 |
.0 |
.0 |
.0 |
.005 |
.025 |
.007 |
.001 |
.0 |
.003 |
.013 |
.001 |
.243 |
.001 |
.005 |
.014 |
.007 |
.137 |
.004 |
.0 |
.124 |
.0 |
.002 |
.0 |
.001 |
.218 |
.003 |
.079 |
.003 |
.001 |
.003 |
.007 |
.016 |
.0 |
.107 |
.0 |
.01 |
.057 |
.001 |
.005 |
.066 |
.004 |
.006 |
.003 |
.444 |
.069 |
.978 |
.001 |
.0 |
.009 |
.0 |
.031 |
.038 |
.025 |
.004 |
.004 |
.0 |
.265 |
.029 |
.409 |
.006 |
.11 |
.0 |
.0 |
.0 |
-- |
-- |
-- |
.009 |
.008 |
.002 |
.355 |
.13 |
.009 |
.033 |
.005 |
.097 |
.0 |
.007 |
.0 |
.001 |
.002 |
.0 |
.02 |
.332 |
.355 |
.014 |
.0 |
.681 |
.006 |
.236 |
.009 |
.001 |
.076 |
.0 |
.036 |
.0 |
.001 |
.005 |
.0 |
.0 |
.367 |
.014 |
.009 |
.001 |
.002 |
.012 |
.002 |
.0 |
.005 |
.0 |
.021 |
.001 |
.04 |
.001 |
.0 |
.002 |
.199 |
.002 |
.022 |
.005 |
.003 |
.003 |
.004 |
.001 |
.002 |
.006 |
.004 |
.006 |
.029 |
.143 |
.135 |
.005 |
.056 |
.999 |
.072 |
.035 |
.002 |
-- |
.554 |
.028 |
1.0 |
.001 |
.002 |
.0 |
.011 |
.013 |
.0 |
.0 |
.0 |
.005 |
.034 |
.577 |
.171 |
.0 |
.008 |
.001 |
.003 |
.014 |
.01 |
.0 |
.0 |
.001 |
.002 |
.025 |
.001 |
.001 |
.007 |
.0 |
.001 |
.0 |
.0 |
.0 |
.181 |
.0 |
.998 |
.991 |
1.0 |
.0 |
.0 |
.0 |
.201 |
.001 |
.004 |
.005 |
.0 |
.004 |
.0 |
.003 |
.004 |
.012 |
-- |
.0 |
.004 |
.0 |
.001 |
.011 |
.001 |
.0 |
.001 |
.001 |
.013 |
.0 |
.011 |
.003 |
.001 |
.014 |
.008 |
.068 |
.003 |
.126 |
.027 |
.002 |
.0 |
.007 |
.146 |
.001 |
.004 |
.001 |
.009 |
.001 |
.004 |
.003 |
.064 |
.001 |
.001 |
.002 |
.019 |
-- |
-- |
-- |
-- |
-- |
-- |
.021 |
.001 |
.002 |
.001 |
.007 |
.02 |
.01 |
.026 |
.657 |
.003 |
.003 |
.025 |
.027 |
.039 |
.081 |
.22 |
.006 |
.015 |
.016 |
.083 |
-- |
.032 |
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
Mapk10
|
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
|
G |
T |
A |
C |
A |
C |
T |
C |
A |
A |
C |
C |
T |
T |
G |
2 |
C |
G |
C |
G |
T |
T |
T |
A |
T |
C |
C |
G |
A |
T |
G |
A |
4 |
3 |
2 |
2 |
C |
- |
- |
- |
- |
T |
G |
T |
G |
T |
C |
C |
T |
G |
T |
C |
G |
- |
G |
22 |
C |
G |
G |
G |
G |
C |
- |
T |
G |
4 |
G |
- |
T |
G |
G |
C |
T |
G |
- |
T |
G |
G |
T |
A |
G |
G |
T |
A |
C |
- |
- |
T |
T |
C |
C |
C |
G |
C |
C |
C |
A |
- |
G |
- |
G |
T |
T |
T |
G |
C |
C |
C |
G |
A |
A |
G |
A |
G |
C |
T |
A |
C |
C |
T |
T |
T |
G |
G |
C |
A |
G |
A |
C |
- |
C |
T |
G |
C |
C |
A |
C |
C |
A |
T |
G |
A |
T |
C |
A |
T |
T |
C |
41 |
- |
- |
G |
T |
C |
C |
T |
A |
G |
C |
C |
A |
- |
G |
T |
T |
A |
G |
T |
C |
T |
G |
G |
A |
C |
C |
C |
G |
G |
C |
C |
G |
A |
A |
G |
A |
- |
C |
G |
C |
G |
T |
C |
G |
T |
C |
C |
- |
T |
C |
C |
G |
A |
G |
G |
G |
C |
- |
T |
T |
C |
T |
G |
A |
2 |
G |
A |
G |
C |
A |
G |
A |
C |
C |
G |
C |
T |
A |
A |
C |
T |
- |
A |
A |
T |
A |
C |
- |
T |
T |
T |
G |
G |
G |
11 |
T |
G |
C |
G |
G |
A |
C |
T |
C |
C |
T |
A |
G |
T |
T |
C |
C |
T |
T |
C |
T |
A |
T |
A |
A |
A |
T |
T |
C |
G |
G |
- |
A |
G |
A |
T |
G |
T |
G |
T |
A |
T |
A |
A |
G |
T |
C |
T |
G |
A |
A |
G |
A |
T |
A |
G |
C |
A |
T |
A |
G |
C |
G |
G |
C |
T |
C |
A |
3 |
C |
C |
A |
G |
T |
C |
A |
G |
T |
C |
C |
G |
G |
T |
T |
C |
T |
G |
A |
G |
G |
- |
G |
A |
A |
G |
C |
C |
T |
C |
A |
A |
- |
C |
G |
T |
A |
T |
G |
A |
T |
G |
A |
A |
G |
A |
G |
A |
G |
T |
T |
7 |
G |
G |
A |
T |
A |
T |
G |
C |
C |
C |
C |
T |
A |
A |
G |
C |
T |
G |
A |
A |
T |
A |
A |
C |
G |
- |
G |
T |
C |
C |
A |
- |
- |
4 |
G |
G |
T |
T |
G |
A |
A |
G |
G |
G |
C |
C |
A |
T |
A |
A |
A |
T |
T |
T |
T |
T |
A |
C |
C |
- |
- |
A |
A |
2 |
C |
A |
- |
T |
A |
- |
A |
- |
- |
A |
T |
- |
A |
T |
C |
C |
A |
T |
T |
C |
A |
- |
G |
G |
T |
2 |
T |
A |
C |
G |
- |
C |
- |
- |
6 |
A |
C |
G |
A |
G |
T |
- |
T |
G |
T |
A |
T |
G |
C |
T |
T |
G |
G |
T |
C |
G |
- |
C |
G |
C |
T |
C |
C |
G |
- |
- |
G |
T |
C |
T |
A |
G |
C |
C |
G |
6 |
T |
G |
T |
G |
G |
G |
T |
A |
G |
T |
G |
G |
T |
T |
G |
A |
A |
A |
T |
A |
C |
T |
C |
C |
- |
- |
C |
C |
A |
C |
T |
G |
G |
C |
C |
A |
T |
T |
A |
C |
G |
- |
A |
T |
C |
G |
G |
C |
T |
G |
T |
C |
A |
C |
C |
A |
T |
T |
G |
T |
C |
C |
T |
G |
T |
T |
T |
- |
30 |
A |
C |
A |
- |
G |
- |
C |
G |
G |
C |
G |
C |
A |
T |
C |
A |
A |
A |
G |
A |
- |
T |
C |
A |
T |
C |
T |
A |
C |
G |
T |
T |
C |
C |
T |
T |
T |
C |
A |
4 |
G |
T |
G |
T |
- |
C |
A |
G |
G |
C |
T |
- |
- |
4 |
T |
A |
A |
T |
A |
A |
T |
T |
- |
15 |
A |
A |
T |
A |
A |
C |
A |
A |
C |
T |
T |
A |
3 |
A |
C |
C |
T |
C |
A |
C |
T |
A |
T |
- |
A |
C |
- |
A |
G |
G |
T |
C |
A |
A |
T |
A |
T |
C |
A |
A |
C |
- |
C |
T |
A |
6 |
- |
A |
A |
G |
- |
A |
C |
T |
C |
A |
T |
G |
T |
A |
C |
T |
G |
T |
G |
A |
T |
A |
A |
C |
- |
C |
T |
G |
T |
A |
2 |
C |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
A
|
C
|
G
|
T
|
C
|
T
|
C
|
T
|
G
|
C
|
G
|
G
|
C
|
C
|
T
|
-
|
G
|
C
|
T
|
A
|
G
|
C
|
C
|
G
|
A
|
A
|
T
|
A
|
T
|
A
|
T
|
G
|
-
|
-
|
-
|
-
|
T
|
2
|
4
|
9
|
47
|
C
|
A
|
A
|
A
|
C
|
T
|
T
|
G
|
A
|
C
|
T
|
A
|
G
|
A
|
-
|
T
|
A
|
A
|
A
|
A
|
T
|
3
|
G
|
A
|
-
|
C
|
3
|
C
|
A
|
A
|
T
|
G
|
A
|
9
|
C
|
A
|
A
|
C
|
G
|
C
|
A
|
C
|
T
|
A
|
A
|
A
|
C
|
C
|
T
|
A
|
T
|
C
|
T
|
T
|
G
|
C
|
6
|
A
|
19
|
A
|
C
|
C
|
C
|
A
|
T
|
T
|
-
|
A
|
G
|
G
|
T
|
T
|
T
|
T
|
C
|
C
|
T
|
A
|
A
|
C
|
A
|
A
|
A
|
-
|
G
|
A
|
G
|
T
|
2
|
T
|
A
|
A
|
T
|
T
|
G
|
T
|
A
|
G
|
C
|
T
|
C
|
C
|
A
|
G
|
C
|
C
|
T
|
-
|
4
|
G
|
-
|
A
|
T
|
G
|
C
|
G
|
A
|
T
|
T
|
G
|
18
|
A
|
C
|
-
|
G
|
A
|
G
|
T
|
C
|
A
|
T
|
G
|
T
|
A
|
T
|
C
|
A
|
T
|
T
|
A
|
G
|
G
|
A
|
C
|
20
|
T
|
A
|
T
|
A
|
C
|
T
|
C
|
C
|
G
|
G
|
T
|
G
|
T
|
T
|
A
|
T
|
A
|
A
|
A
|
T
|
2
|
C
|
C
|
A
|
G
|
-
|
G
|
-
|
A
|
G
|
A
|
T
|
T
|
A
|
G
|
T
|
T
|
A
|
T
|
C
|
G
|
G
|
T
|
C
|
A
|
C
|
C
|
C
|
G
|
T
|
A
|
C
|
C
|
C
|
A
|
-
|
A
|
-
|
C
|
T
|
T
|
C
|
T
|
C
|
T
|
A
|
T
|
G
|
G
|
G
|
A
|
C
|
C
|
T
|
T
|
G
|
C
|
T
|
A
|
G
|
C
|
T
|
G
|
G
|
G
|
C
|
T
|
A
|
C
|
G
|
G
|
A
|
G
|
C
|
T
|
C
|
A
|
C
|
G
|
C
|
G
|
G
|
C
|
C
|
T
|
C
|
C
|
G
|
G
|
A
|
G
|
C
|
G
|
T
|
T
|
G
|
C
|
G
|
A
|
A
|
A
|
A
|
A
|
A
|
T
|
T
|
-
|
T
|
T
|
C
|
A
|
C
|
T
|
T
|
T
|
C
|
G
|
T
|
A
|
A
|
C
|
C
|
T
|
C
|
A
|
C
|
A
|
A
|
A
|
A
|
T
|
-
|
T
|
T
|
G
|
C
|
T
|
T
|
G
|
2
|
T
|
A
|
C
|
G
|
C
|
A
|
G
|
C
|
C
|
G
|
G
|
C
|
G
|
A
|
C
|
C
|
C
|
G
|
-
|
A
|
A
|
G
|
C
|
C
|
C
|
A
|
T
|
A
|
A
|
G
|
C
|
G
|
T
|
-
|
T
|
C
|
A
|
G
|
T
|
C
|
G
|
G
|
G
|
C
|
T
|
C
|
C
|
G
|
T
|
-
|
T
|
T
|
-
|
A
|
A
|
G
|
G
|
C
|
G
|
G
|
A
|
A
|
A
|
T
|
T
|
G
|
C
|
-
|
G
|
C
|
G
|
C
|
C
|
C
|
C
|
G
|
T
|
-
|
G
|
C
|
-
|
C
|
-
|
A
|
T
|
T
|
A
|
T
|
C
|
-
|
T
|
A
|
G
|
C
|
T
|
G
|
-
|
T
|
T
|
G
|
C
|
G
|
G
|
G
|
C
|
A
|
T
|
C
|
-
|
C
|
C
|
G
|
C
|
4
|
G
|
A
|
A
|
-
|
G
|
T
|
A
|
G
|
T
|
-
|
16
|
C
|
A
|
C
|
G
|
G
|
T
|
A
|
C
|
C
|
A
|
C
|
C
|
T
|
A
|
A
|
G
|
T
|
G
|
C
|
T
|
T
|
A
|
5
|
12
|
A
|
C
|
G
|
C
|
G
|
A
|
A
|
T
|
A
|
-
|
C
|
C
|
C
|
T
|
A
|
A
|
C
|
G
|
T
|
G
|
A
|
T
|
C
|
C
|
A
|
G
|
G
|
C
|
C
|
C
|
T
|
C
|
T
|
T
|
T
|
G
|
T
|
A
|
G
|
T
|
C
|
A
|
A
|
T
|
T
|
G
|
A
|
A
|
G
|
-
|
A
|
T
|
G
|
A
|
T
|
T
|
A
|
T
|
-
|
A
|
C
|
A
|
G
|
T
|
T
|
G
|
-
|
C
|
A
|
G
|
G
|
G
|
A
|
C
|
G
|
C
|
G
|
A
|
-
|
G
|
T
|
C
|
A
|
T
|
A
|
T
|
C
|
A
|
T
|
A
|
A
|
G
|
C
|
G
|
G
|
G
|
T
|
A
|
G
|
2
|
-
|
T
|
G
|
T/A
|
G
|
C
|
G
|
T
|
A
|
C
|
C
|
T
|
T
|
C
|
G
|
C
|
G
|
T
|
-
|
A
|
C
|
T
|
C
|
A
|
T
|
G
|
A
|
A
|
T
|
G
|
4
|
4
|
-
|
G
|
G
|
G
|
G
|
T
|
G
|
G
|
C
|
15
|
-
|
C
|
C
|
C
|
G
|
G
|
T
|
C
|
G
|
T
|
A
|
C
|
G
|
-
|
G
|
T
|
T
|
C
|
T
|
G
|
T
|
G
|
T
|
C
|
A
|
G
|
T
|
12
|
-
|
A
|
T
|
C
|
T
|
G
|
G
|
C
|
T
|
C
|
T
|
G
|
C
|
T
|
A/G
|
T
|
C
|
C
|
-
|
C
|
T
|
T
|
A
|
5
|
T
|
T
|
C
|
T
|
G
|
C
|
A
|
C
|
G
|
G
|
G
|
A
|
C
|
A
|
T
|
C
|
G
|
G
|
T
|
G
|
T
|
A
|
A
|
C
|
G
|
-
|
A
|
|