|
.014 |
.0 |
.356 |
.028 |
.085 |
.071 |
.063 |
.001 |
.009 |
.232 |
.032 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
.111 |
.978 |
.054 |
.033 |
.003 |
.005 |
.052 |
.051 |
.028 |
.028 |
.001 |
.0 |
.003 |
.001 |
.0 |
-- |
.015 |
.0 |
.002 |
.001 |
.0 |
.001 |
.0 |
.0 |
.001 |
.001 |
.0 |
.0 |
.0 |
.0 |
.0 |
.002 |
.002 |
.0 |
.089 |
.0 |
.002 |
.0 |
.004 |
.0 |
.0 |
.046 |
.038 |
.015 |
.011 |
.345 |
.019 |
.002 |
.017 |
.035 |
.0 |
.076 |
.083 |
.059 |
.098 |
.366 |
.037 |
.066 |
.119 |
.06 |
.014 |
.001 |
.002 |
.002 |
.004 |
.0 |
.014 |
.0 |
.001 |
.009 |
.006 |
.004 |
.001 |
.002 |
.001 |
.233 |
.002 |
.011 |
.011 |
.0 |
.672 |
.012 |
-- |
.004 |
.006 |
.004 |
.029 |
.186 |
.149 |
.02 |
.039 |
.014 |
.002 |
.005 |
.062 |
.028 |
.0 |
.002 |
.029 |
.007 |
.019 |
.007 |
.015 |
.015 |
.136 |
.011 |
.003 |
.001 |
.002 |
.008 |
.006 |
.083 |
.082 |
.0 |
.003 |
-- |
-- |
.004 |
1.0 |
.008 |
.0 |
.73 |
.045 |
.004 |
.0 |
.998 |
.227 |
.003 |
.0 |
.01 |
.005 |
.0 |
.001 |
.002 |
.001 |
.017 |
.106 |
.213 |
.017 |
.03 |
.0 |
.009 |
.018 |
.0 |
.009 |
-- |
-- |
-- |
.002 |
.082 |
.046 |
.001 |
.002 |
.002 |
.0 |
.641 |
.0 |
.0 |
.002 |
.134 |
.002 |
.02 |
.007 |
.0 |
.001 |
.0 |
.498 |
.636 |
.001 |
.005 |
.0 |
.003 |
.001 |
.16 |
.007 |
.207 |
.007 |
.005 |
.007 |
.0 |
.06 |
.004 |
.004 |
.021 |
.037 |
.096 |
.515 |
.312 |
.015 |
.018 |
.121 |
.008 |
.0 |
.006 |
.001 |
.0 |
-- |
.182 |
.001 |
.003 |
.0 |
.0 |
.001 |
.193 |
.173 |
.105 |
.002 |
.002 |
.001 |
.012 |
.037 |
.034 |
.007 |
.02 |
.123 |
.0 |
.099 |
.0 |
.3 |
.012 |
.0 |
.056 |
.006 |
.001 |
.113 |
1.0 |
.001 |
.0 |
.005 |
.007 |
.182 |
.503 |
.602 |
.044 |
.006 |
.003 |
.001 |
.013 |
.011 |
.005 |
.009 |
.003 |
.0 |
.004 |
.004 |
.005 |
.002 |
.003 |
.094 |
.077 |
.047 |
.002 |
.018 |
.001 |
.0 |
.152 |
.002 |
.0 |
.0 |
.001 |
.003 |
.677 |
.004 |
.0 |
.001 |
.026 |
.003 |
.002 |
.002 |
.056 |
.006 |
.031 |
.384 |
.021 |
.02 |
.056 |
.013 |
.35 |
.022 |
.0 |
.003 |
.0 |
.0 |
.122 |
.956 |
.002 |
.0 |
.0 |
1.0 |
.993 |
.002 |
.009 |
.001 |
.001 |
.001 |
.009 |
.066 |
.001 |
.212 |
.007 |
.067 |
.006 |
.491 |
.001 |
.49 |
.004 |
.002 |
.012 |
.011 |
.994 |
.989 |
.004 |
.0 |
.002 |
.0 |
.001 |
.022 |
.001 |
.0 |
.004 |
.008 |
.001 |
.031 |
.0 |
.006 |
.001 |
-- |
.002 |
.026 |
.0 |
.0 |
.0 |
.0 |
.001 |
.0 |
.003 |
.005 |
.001 |
.001 |
.0 |
.0 |
.001 |
.004 |
.0 |
.014 |
.0 |
.0 |
.0 |
.0 |
.002 |
.001 |
.037 |
.027 |
.001 |
.004 |
.001 |
.0 |
.0 |
.0 |
.002 |
.009 |
.0 |
.337 |
.0 |
.0 |
.003 |
.0 |
.0 |
.009 |
.0 |
.241 |
.003 |
.001 |
.007 |
.001 |
.895 |
.002 |
.003 |
.001 |
.002 |
-- |
.001 |
.0 |
.187 |
.001 |
.022 |
.003 |
.011 |
.112 |
.049 |
.095 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
.261 |
.002 |
.041 |
.025 |
.0 |
.011 |
.003 |
.025 |
.002 |
.0 |
.0 |
.062 |
.0 |
.909 |
.081 |
.926 |
.0 |
.002 |
.001 |
.0 |
.005 |
.001 |
.006 |
.001 |
.312 |
-- |
-- |
-- |
-- |
.004 |
.003 |
.002 |
.013 |
.016 |
.002 |
.984 |
1.0 |
.998 |
.036 |
.043 |
.121 |
.005 |
.076 |
.001 |
.0 |
.993 |
.0 |
.038 |
.002 |
.012 |
.0 |
.0 |
.005 |
.001 |
.0 |
.0 |
.003 |
.001 |
.001 |
.002 |
.0 |
.015 |
.007 |
.001 |
.003 |
.002 |
.013 |
.002 |
.003 |
.001 |
.008 |
.001 |
.0 |
.018 |
.581 |
.284 |
.325 |
.091 |
.288 |
.0 |
.0 |
|
Ldlrad4
|
Ldlrad4
|
Ldlrad4
|
Ldlrad4
|
Ldlrad4
|
Ldlrad4
|
Ldlrad4
|
Ldlrad4
|
Ldlrad4
|
Ldlrad4
|
Ldlrad4
|
Ldlrad4
|
Ldlrad4
|
Ldlrad4
|
Ldlrad4
|
Ldlrad4
|
Ldlrad4
|
Ldlrad4
|
Ldlrad4
|
Ldlrad4
|
Ldlrad4
|
Ldlrad4
|
Ldlrad4
|
Ldlrad4
|
Ldlrad4
|
Ldlrad4
|
Ldlrad4
|
Ldlrad4
|
Ldlrad4
|
Ldlrad4
|
Ldlrad4
|
Ldlrad4
|
Ldlrad4
|
Ldlrad4
|
Ldlrad4
|
Ldlrad4
|
Ldlrad4
|
Ldlrad4
|
Ldlrad4
|
Ldlrad4
|
Ldlrad4
|
Ldlrad4
|
Ldlrad4
|
Ldlrad4
|
Ldlrad4
|
Ldlrad4
|
Ldlrad4
|
Ldlrad4
|
Ldlrad4
|
Ldlrad4
|
Ldlrad4
|
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
Gapdh-ps118
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
|
A |
A |
A |
A |
C |
T |
T |
A |
A |
A |
A |
C |
A |
G |
G |
T |
C |
C |
A |
T |
A |
A |
A |
A |
A |
T |
G |
A |
G |
C |
C |
T |
C |
A |
A |
C |
A |
G |
T |
A |
C |
C |
A |
T |
C |
A |
T |
T |
T |
G |
C |
A |
G |
T |
A |
C |
C |
C |
C |
A |
T |
T |
G |
A |
A |
G |
A |
C |
C |
T |
G |
T |
A |
A |
T |
A |
G |
G |
G |
G |
G |
G |
C |
T |
G |
T |
G |
T |
G |
A |
T |
C |
A |
C |
G |
T |
A |
T |
A |
T |
T |
A |
C |
G |
T |
A |
C |
C |
G |
T |
T |
A |
C |
G |
T |
A |
G |
G |
G |
G |
A |
C |
T |
G |
A |
A |
T |
C |
G |
C |
C |
C |
G |
G |
C |
G |
C |
G |
G |
T |
G |
A |
C |
T |
G |
G |
T |
A |
T |
A |
T |
C |
G |
A |
T |
A |
G |
A |
A |
T |
G |
T |
A |
C |
A |
A |
T |
G |
C |
A |
A |
G |
C |
T |
G |
A |
A |
A |
C |
T |
C |
T |
G |
G |
A |
G |
G |
C |
A |
T |
T |
T |
T |
T |
T |
T |
A |
T |
G |
T |
A |
G |
C |
C |
G |
C |
C |
G |
A |
T |
T |
A |
G |
A |
A |
T |
G |
A |
C |
A |
A |
A |
C |
C |
C |
G |
A |
T |
T |
G |
C |
C |
G |
G |
T |
T |
A |
G |
G |
G |
A |
C |
T |
A |
T |
C |
G |
A |
C |
G |
A |
T |
T |
G |
C |
T |
G |
A |
C |
T |
A |
G |
T |
C |
T |
A |
T |
T |
C |
C |
T |
T |
C |
C |
G |
T |
A |
A |
A |
C |
C |
G |
T |
A |
T |
T |
T |
T |
T |
A |
C |
A |
T |
T |
T |
T |
T |
G |
C |
G |
C |
T |
C |
C |
C |
G |
C |
A |
T |
A |
C |
G |
T |
T |
G |
G |
T |
G |
G |
A |
C |
G |
T |
G |
C |
G |
A |
A |
A |
A |
G |
G |
A |
G |
A |
T |
A |
T |
A |
C |
T |
C |
C |
T |
T |
A |
C |
C |
T |
G |
A |
T |
G |
G |
A |
C |
C |
A |
G |
A |
A |
C |
T |
T |
A |
A |
G |
G |
G |
G |
G |
A |
G |
T |
G |
T |
G |
A |
A |
A |
T |
A |
C |
T |
C |
G |
C |
C |
A |
C |
A |
T |
C |
A |
C |
G |
C |
G |
C |
C |
A |
T |
T |
A |
C |
G |
A |
C |
T |
A |
G |
G |
A |
C |
G |
T |
G |
G |
C |
C |
T |
G |
C |
T |
A |
T |
T |
A |
T |
C |
G |
G |
G |
C |
T |
G |
G |
A |
C |
A |
A |
T |
A |
T |
A |
T |
C |
G |
G |
C |
G |
G |
C |
C |
C |
G |
T |
T |
G |
A |
A |
G |
G |
G |
A |
A |
C |
T |
C |
C |
C |
G |
C |
G |
A |
A |
C |
G |
G |
G |
C |
T |
T |
T |
T |
C |
G |
A |
G |
C |
C |
C |
T |
G |
T |
C |
A |
G |
G |
A |
G |
A |
A |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
G
|
G
|
G
|
A/G
|
T
|
G
|
A
|
C
|
G
|
G
|
G
|
G
|
C
|
A
|
G/A
|
C
|
A
|
T
|
C
|
C
|
T
|
G
|
G
|
C
|
G
|
T/A
|
G/C
|
T
|
A
|
T
|
A
|
C
|
A
|
G
|
G
|
T
|
T
|
A
|
C
|
G
|
A
|
T
|
C
|
A
|
A
|
T
|
C
|
C
|
A
|
T
|
T
|
G
|
A
|
A
|
G
|
T
|
T
|
A
|
T
|
G
|
C
|
C
|
T
|
G
|
T
|
C
|
G
|
T
|
T
|
C
|
A
|
A
|
G
|
G
|
G
|
G
|
T
|
C
|
T
|
A
|
A
|
A
|
T
|
C
|
A
|
C
|
A
|
C
|
C
|
T
|
A
|
T
|
G
|
A
|
T
|
C
|
G
|
C
|
C
|
C
|
C
|
G
|
C/T
|
A
|
C
|
T
|
T
|
G
|
A
|
C
|
G
|
A/G
|
T
|
A
|
A
|
G
|
A
|
A
|
A
|
A
|
G
|
T
|
C
|
G/C
|
G
|
G
|
A
|
T
|
A
|
T
|
T
|
G
|
A
|
A
|
T
|
T
|
A
|
A
|
A
|
C
|
A
|
A/C
|
T
|
C
|
T
|
G/C
|
C
|
T
|
G
|
G
|
C
|
T
|
A
|
G
|
G
|
G
|
A
|
C
|
G
|
A
|
G/A
|
C
|
G
|
A
|
G
|
G
|
C
|
T
|
A
|
T
|
T
|
C
|
C/A
|
G
|
C
|
C
|
C
|
G
|
T
|
C
|
G
|
C
|
C
|
A
|
C
|
A
|
A
|
T
|
G
|
A
|
C
|
C
|
C
|
T/A
|
T/G
|
C
|
G
|
C
|
A
|
C
|
G
|
A
|
T
|
T
|
A
|
T
|
T
|
A
|
C
|
C
|
C
|
G
|
A
|
G
|
T
|
C
|
T
|
G
|
T
|
C
|
G
|
T
|
G
|
C/T
|
T
|
A
|
C
|
C
|
G
|
A
|
T
|
T
|
A
|
A
|
C
|
C
|
G
|
A
|
C
|
A
|
G
|
A
|
C
|
C
|
C
|
T
|
A
|
G
|
T
|
A
|
G
|
C
|
C
|
C
|
A
|
C
|
A
|
G
|
T
|
A
|
G
|
A
|
C
|
T
|
G
|
G
|
C
|
C
|
T
|
T
|
C
|
C
|
T
|
T
|
A
|
C
|
G
|
G
|
G
|
T
|
T
|
A
|
A
|
C
|
C
|
C
|
C
|
C
|
A
|
C
|
G
|
G
|
C
|
A
|
C
|
C
|
C
|
A
|
T
|
A
|
A
|
A
|
A
|
A
|
T
|
A
|
T
|
G
|
C
|
G
|
T
|
C
|
C
|
A
|
A
|
A
|
C
|
T
|
A
|
G
|
A
|
A
|
C
|
A
|
T
|
A
|
C
|
G
|
G
|
G
|
A
|
A
|
G
|
C
|
G
|
G
|
G
|
C
|
G
|
T
|
C
|
T
|
A
|
C
|
C
|
C
|
T
|
T
|
C
|
T
|
G
|
C
|
A
|
A
|
G
|
T
|
T
|
G
|
A
|
T
|
G
|
T
|
C
|
C
|
G
|
G
|
T
|
A
|
A
|
A
|
T
|
C
|
C
|
C
|
A
|
C
|
A
|
C
|
G
|
G
|
C
|
A/G
|
T
|
G
|
T
|
T
|
G
|
G
|
G
|
T
|
G
|
A
|
G
|
T
|
T
|
A
|
T
|
A
|
T
|
T
|
C
|
C
|
C
|
G
|
T
|
A
|
G
|
T
|
C
|
G
|
A
|
T
|
G
|
G
|
C
|
A
|
C
|
A
|
T
|
G
|
C
|
A
|
T
|
C
|
G
|
C
|
C
|
T
|
C
|
T
|
A
|
A
|
A
|
A
|
C
|
A
|
A
|
C
|
T
|
G
|
C
|
C
|
G
|
C
|
G
|
C
|
G
|
G/C
|
G/C
|
C/T
|
C
|
C
|
T
|
G
|
T
|
A
|
C
|
C
|
A
|
G
|
G
|
A
|
A
|
A
|
G
|
C
|
G
|
C
|
T
|
T
|
T
|
G/A
|
T
|
A
|
G
|
G
|
A
|
A
|
A
|
T
|
T
|
A
|
C
|
C
|
A
|
T
|
A
|
T
|
A
|
A
|
G
|
T
|
C
|
A
|
G
|
T
|
G
|
A
|
A
|
C
|
C
|
G
|
G
|
|