|
.0 |
.0 |
.0 |
.003 |
.001 |
.002 |
.0 |
.012 |
.001 |
.165 |
.037 |
.002 |
.001 |
.0 |
.003 |
.0 |
.01 |
.072 |
.016 |
.001 |
.0 |
.003 |
.001 |
.001 |
.003 |
.021 |
.004 |
.007 |
.134 |
.003 |
.004 |
.005 |
.047 |
.032 |
.007 |
.023 |
.001 |
.001 |
.0 |
.004 |
.011 |
.038 |
.006 |
.002 |
.005 |
.006 |
.002 |
.011 |
-- |
.016 |
.011 |
.0 |
.0 |
.0 |
.0 |
.0 |
.04 |
.012 |
.001 |
.002 |
.004 |
.003 |
.0 |
.0 |
.003 |
.047 |
.0 |
.324 |
.37 |
.417 |
.624 |
.685 |
.691 |
.262 |
.252 |
.01 |
.003 |
.041 |
.003 |
.001 |
.001 |
.0 |
.0 |
.001 |
.003 |
.002 |
.009 |
.014 |
.02 |
.006 |
.006 |
.0 |
.002 |
.001 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
.001 |
.0 |
.0 |
.0 |
.0 |
.001 |
.0 |
.002 |
.005 |
.034 |
.001 |
.0 |
.014 |
.103 |
.13 |
.063 |
.09 |
.447 |
.001 |
.003 |
.026 |
.0 |
.035 |
.059 |
.042 |
.324 |
.081 |
.005 |
.006 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
.001 |
.0 |
.017 |
.006 |
.0 |
.506 |
.467 |
.05 |
.014 |
.055 |
.025 |
.03 |
.012 |
.001 |
.003 |
.005 |
.006 |
.045 |
-- |
-- |
-- |
.707 |
.091 |
.052 |
.001 |
.001 |
.013 |
.0 |
.001 |
.001 |
.014 |
.0 |
.003 |
.003 |
.009 |
.006 |
.004 |
.0 |
.008 |
.006 |
.006 |
.0 |
-- |
.188 |
.611 |
.097 |
.121 |
.014 |
.012 |
.027 |
.046 |
-- |
-- |
.014 |
.528 |
.003 |
.779 |
.939 |
.991 |
.986 |
.021 |
.0 |
.001 |
.002 |
.048 |
.002 |
.001 |
.0 |
.002 |
.152 |
.11 |
.07 |
.421 |
.145 |
.058 |
.061 |
.081 |
.191 |
.312 |
.065 |
.253 |
.961 |
1.0 |
.637 |
.991 |
.88 |
.993 |
.998 |
.986 |
.987 |
.847 |
.705 |
.328 |
.668 |
.907 |
.961 |
.996 |
.986 |
.884 |
.686 |
.107 |
.002 |
.002 |
.01 |
.287 |
.0 |
.046 |
.066 |
.018 |
.028 |
.413 |
.027 |
.01 |
.013 |
.005 |
.001 |
.001 |
.0 |
.0 |
.001 |
.621 |
.035 |
.085 |
.001 |
.249 |
.087 |
.285 |
.171 |
.021 |
.021 |
.0 |
.001 |
.001 |
.0 |
.009 |
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
|
Il2ra
|
Il2ra
|
Il2ra
|
Il2ra
|
Il2ra
|
Il2ra
|
Il2ra
|
Il2ra
|
Il2ra
|
Il2ra
|
Il2ra
|
Il2ra
|
Il2ra
|
Il2ra
|
Il2ra
|
Il2ra
|
Il2ra
|
Il2ra
|
Il2ra
|
Il2ra
|
Il2ra
|
Il2ra
|
Il2ra
|
Il2ra
|
Il2ra
|
Il2ra
|
Il2ra
|
Il2ra
|
Il2ra
|
|
T |
A |
T |
T |
C |
C |
C |
T |
T |
A |
C |
G |
C |
G |
G |
G |
T |
C |
A |
A |
C |
C |
G |
G |
G |
T |
2 |
2 |
- |
2 |
G |
C |
G |
C |
G |
G |
- |
C |
T |
A |
3 |
G |
G |
T |
A |
C |
C |
G |
A |
T |
T |
A |
T |
C |
A |
A |
T |
A |
T |
A |
G |
G |
A |
T |
T |
G |
C |
C |
C |
C |
- |
- |
- |
G |
G |
T |
C |
A |
- |
T |
4 |
G |
A |
A |
T |
- |
A |
C |
C |
T |
C |
C |
T |
A |
A |
A |
C |
- |
A |
A |
A |
C |
C |
T |
T |
C |
2 |
G |
A |
2 |
T |
C |
T |
A |
A |
C |
A |
C |
T |
A |
C |
G |
G |
C |
T |
C |
G |
G |
C |
2 |
C |
A |
T |
15 |
G |
A |
C |
- |
C |
- |
C |
A |
- |
- |
3 |
- |
G |
C |
- |
2 |
T |
G |
A |
T |
C |
C |
- |
A |
A |
A |
T |
G |
- |
G |
T |
T |
T |
- |
G |
G |
A |
G |
- |
T |
G |
T |
3 |
T |
G |
G |
C |
T |
A |
C |
- |
T |
C |
T |
A |
T |
G |
G |
T |
A |
- |
C |
G |
A |
T |
- |
C |
G |
A |
G |
T |
G |
A |
T |
C |
A |
A |
T |
A |
G |
G |
T |
A |
T |
- |
A |
G |
- |
- |
- |
A |
A |
- |
- |
- |
A |
A |
- |
- |
- |
- |
- |
- |
- |
- |
- |
- |
T |
A |
- |
- |
A |
G |
A |
- |
C |
- |
- |
G |
- |
- |
- |
A |
A |
A |
T |
C |
T |
2 |
C |
C |
A |
A |
A |
G |
A |
G |
G |
C |
C |
T |
5 |
T |
C |
6 |
A |
T |
A |
G |
C |
T |
A |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
C
|
C
|
C
|
C
|
A
|
T
|
T
|
C
|
C
|
G
|
T
|
A
|
G
|
A
|
A
|
T
|
C
|
T
|
G
|
G
|
T
|
T
|
T
|
T
|
T
|
A
|
-
|
-
|
2
|
-
|
A
|
T
|
A
|
T
|
C
|
A
|
A
|
T
|
C
|
G
|
3/-
|
A
|
A
|
C
|
G
|
T
|
G
|
T
|
T
|
A
|
C
|
G
|
C
|
A
|
G
|
G
|
C
|
C
|
C
|
G
|
C
|
A
|
G
|
G
|
G
|
A
|
T
|
C/G
|
C/G
|
C/G
|
-/2
|
-/2
|
-/2
|
G/C
|
A
|
C
|
A
|
G
|
4
|
A
|
-
|
A
|
G
|
G
|
C
|
4
|
G
|
T
|
T
|
C
|
T
|
T
|
-
|
C
|
C
|
C
|
T
|
6
|
C
|
C
|
C
|
G
|
T
|
A
|
C
|
A
|
-
|
A
|
G
|
-
|
-
|
T
|
C
|
G
|
G
|
A
|
G
|
A
|
C
|
C
|
T
|
A
|
A
|
T
|
G
|
T
|
A
|
A
|
G
|
-
|
-
|
G
|
G
|
-
|
A
|
-
|
-
|
2
|
-
|
A
|
A
|
T
|
G
|
T
|
-
|
T
|
-
|
-
|
G
|
-
|
C
|
A
|
C
|
C
|
T
|
T
|
2
|
-
|
G
|
C
|
C
|
A
|
A
|
A
|
C
|
C
|
C
|
-/C
|
A
|
T
|
-
|
-
|
C
|
-
|
-
|
C
|
-
|
G
|
A
|
A
|
T
|
A
|
G
|
T
|
C
|
-
|
T
|
A
|
G
|
C
|
C
|
A
|
C
|
G
|
T
|
T
|
T
|
G
|
-
|
G/G
|
G
|
A
|
G
|
A
|
C
|
A
|
G
|
C
|
G
|
T
|
-
|
A
|
G
|
-
|
A
|
A
|
T
|
-
|
T
|
G
|
A
|
G
|
G
|
G
|
G
|
T
|
T
|
G
|
2
|
-
|
-
|
A
|
2
|
G
|
A
|
A
|
G
|
G
|
A
|
2
|
G
|
G
|
G
|
3
|
G
|
G
|
A
|
G
|
A
|
-
|
G
|
G
|
-
|
C
|
T
|
T
|
G
|
G
|
-
|
A
|
A
|
C
|
-
|
C/T
|
C/T
|
A/G
|
G
|
G
|
A
|
G
|
A
|
A
|
A
|
-
|
G
|
-
|
C
|
A
|
-
|
T
|
A
|
T
|
A
|
A
|
C
|
-
|
|