|
.963 |
.987 |
.002 |
.0 |
.0 |
.0 |
.0 |
.989 |
.952 |
.006 |
.002 |
.0 |
.0 |
.0 |
.0 |
.001 |
.205 |
.783 |
.036 |
.145 |
.003 |
.129 |
.005 |
.015 |
.002 |
.001 |
.0 |
.001 |
.001 |
.004 |
.008 |
.016 |
.003 |
.0 |
.008 |
.067 |
.0 |
.0 |
.0 |
.001 |
.0 |
.57 |
.0 |
.01 |
.0 |
.007 |
.0 |
.002 |
.21 |
.0 |
.015 |
.001 |
.0 |
.739 |
.002 |
.021 |
.955 |
.0 |
.001 |
.0 |
.006 |
.004 |
.0 |
.0 |
.026 |
.0 |
.026 |
.063 |
.006 |
.012 |
.001 |
.0 |
.01 |
.001 |
.017 |
.0 |
.005 |
.0 |
.001 |
.006 |
.002 |
.0 |
.001 |
.0 |
.888 |
.003 |
.29 |
.001 |
.0 |
.157 |
.453 |
.0 |
.003 |
.001 |
.007 |
.004 |
.035 |
.141 |
.078 |
.001 |
.0 |
.0 |
.071 |
.06 |
.035 |
.002 |
.0 |
.0 |
.096 |
.002 |
.001 |
.59 |
.875 |
.006 |
.268 |
.001 |
.002 |
.001 |
.002 |
.059 |
.015 |
.0 |
.001 |
.009 |
.014 |
.001 |
.0 |
.003 |
.05 |
.031 |
.0 |
.045 |
.001 |
.0 |
.001 |
.079 |
.0 |
.0 |
.0 |
.012 |
.036 |
.011 |
.005 |
.158 |
.009 |
.014 |
.001 |
.008 |
.333 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
.005 |
.001 |
.001 |
.358 |
.001 |
.0 |
1.0 |
.004 |
.004 |
.104 |
.073 |
.002 |
.029 |
.019 |
.043 |
.005 |
.001 |
.003 |
.0 |
.0 |
.009 |
.0 |
.0 |
.0 |
.001 |
.0 |
.0 |
.116 |
.0 |
.019 |
.022 |
.0 |
.002 |
.001 |
.0 |
.0 |
.011 |
1.0 |
.003 |
.008 |
.0 |
.003 |
.004 |
-- |
.002 |
.001 |
.006 |
.005 |
.01 |
.003 |
.004 |
.001 |
.063 |
.0 |
.001 |
.058 |
.0 |
.001 |
.0 |
.003 |
.024 |
.008 |
.004 |
.001 |
.001 |
.022 |
.0 |
.002 |
.006 |
.0 |
.0 |
.008 |
.004 |
.009 |
.0 |
.002 |
.016 |
.017 |
.003 |
.012 |
.006 |
.005 |
.0 |
.005 |
.149 |
.001 |
.002 |
.002 |
.982 |
.74 |
.001 |
.0 |
1.0 |
.007 |
.019 |
.342 |
-- |
-- |
-- |
-- |
.081 |
.058 |
.013 |
.432 |
.466 |
.001 |
.0 |
.0 |
.032 |
.001 |
.0 |
.001 |
.0 |
.043 |
.991 |
.0 |
.002 |
.0 |
.139 |
-- |
-- |
.001 |
.011 |
.005 |
.002 |
.001 |
.0 |
.0 |
.0 |
.009 |
.029 |
.0 |
.008 |
.084 |
.007 |
.0 |
.004 |
.001 |
.0 |
.0 |
.0 |
.001 |
.003 |
.087 |
.004 |
.877 |
.0 |
.0 |
.925 |
.002 |
.007 |
.0 |
.0 |
.01 |
.162 |
.002 |
.008 |
.0 |
.0 |
.0 |
.0 |
.04 |
.001 |
.0 |
.001 |
.008 |
.0 |
.002 |
.005 |
1.0 |
.015 |
.004 |
.0 |
.004 |
.089 |
.076 |
.005 |
.0 |
.003 |
.001 |
.0 |
.001 |
.0 |
.059 |
.453 |
.001 |
.0 |
.0 |
.003 |
.2 |
.0 |
.113 |
.004 |
.0 |
.0 |
.0 |
.0 |
.009 |
.001 |
.004 |
.024 |
.022 |
.07 |
.002 |
.003 |
.001 |
.026 |
.019 |
.0 |
.001 |
.0 |
.202 |
.001 |
.019 |
.006 |
.0 |
.0 |
.235 |
.662 |
.095 |
.0 |
.041 |
.007 |
.001 |
.0 |
.0 |
.0 |
.0 |
.002 |
.004 |
.002 |
.004 |
.005 |
.001 |
.0 |
.007 |
.003 |
.003 |
.003 |
.009 |
.009 |
.0 |
.15 |
.003 |
.0 |
.0 |
.0 |
.002 |
.0 |
.004 |
.001 |
.001 |
.0 |
.0 |
.0 |
.002 |
.0 |
.0 |
.007 |
.022 |
.0 |
.001 |
.0 |
.084 |
.011 |
.237 |
.003 |
.745 |
.025 |
-- |
-- |
-- |
-- |
.789 |
.959 |
.005 |
.006 |
.016 |
.001 |
.003 |
.002 |
.649 |
.0 |
.016 |
.001 |
.029 |
.096 |
.002 |
.052 |
.054 |
.011 |
.116 |
.0 |
.06 |
.0 |
.005 |
.508 |
.0 |
.0 |
.0 |
.001 |
.0 |
.0 |
.0 |
.001 |
.0 |
.004 |
.0 |
.001 |
.723 |
.001 |
.004 |
.051 |
.023 |
.024 |
.088 |
.0 |
.004 |
.017 |
.002 |
.002 |
.002 |
.011 |
.004 |
.0 |
.001 |
.004 |
.001 |
.0 |
.017 |
.008 |
.001 |
.0 |
.0 |
.002 |
.015 |
.0 |
.0 |
.0 |
.001 |
.002 |
.0 |
.0 |
.0 |
.0 |
.0 |
.0 |
.0 |
.002 |
.0 |
.002 |
.011 |
.109 |
.005 |
.005 |
.002 |
.001 |
.019 |
.001 |
.001 |
.0 |
.0 |
.0 |
.0 |
.002 |
.0 |
.005 |
.006 |
.997 |
.996 |
.001 |
.0 |
.005 |
.001 |
.0 |
.006 |
.007 |
.108 |
.09 |
.003 |
.001 |
.0 |
.004 |
.158 |
.161 |
.0 |
.0 |
.006 |
.433 |
.076 |
.279 |
.305 |
.302 |
.153 |
.155 |
.164 |
.078 |
.005 |
.015 |
.001 |
.003 |
.0 |
.002 |
.008 |
.005 |
.001 |
.001 |
.002 |
.016 |
.001 |
.002 |
.113 |
.151 |
.031 |
.109 |
.07 |
.074 |
.007 |
.001 |
.014 |
.033 |
.079 |
.071 |
.073 |
.005 |
.003 |
.998 |
.0 |
.007 |
.0 |
.0 |
.002 |
.001 |
.009 |
.312 |
.0 |
.021 |
.001 |
.014 |
.982 |
.999 |
.874 |
-- |
.02 |
.001 |
.009 |
.0 |
.001 |
.017 |
.004 |
.0 |
.074 |
.007 |
.054 |
.0 |
.0 |
.119 |
.001 |
.0 |
.002 |
.041 |
.066 |
.05 |
.006 |
.0 |
.001 |
.0 |
.877 |
.0 |
.73 |
.0 |
.668 |
.0 |
.048 |
.017 |
.001 |
.004 |
.003 |
.113 |
.074 |
.016 |
.001 |
.948 |
.001 |
.172 |
.0 |
.053 |
-- |
.001 |
.023 |
.986 |
.0 |
.007 |
.0 |
.001 |
.001 |
.277 |
.0 |
.03 |
.0 |
.005 |
.231 |
.0 |
.0 |
.001 |
.004 |
.048 |
.009 |
.043 |
-- |
.027 |
.026 |
.032 |
.121 |
.001 |
.414 |
.42 |
.038 |
1.0 |
.062 |
.0 |
.001 |
.018 |
.129 |
.201 |
.001 |
.014 |
.016 |
.014 |
.002 |
.029 |
1.0 |
.0 |
.0 |
.002 |
.001 |
.002 |
.0 |
.001 |
.008 |
.005 |
.001 |
.069 |
.017 |
.03 |
.07 |
.002 |
.0 |
.0 |
1.0 |
.999 |
.007 |
.013 |
.045 |
.0 |
.0 |
.0 |
.0 |
.001 |
.0 |
.003 |
.003 |
.003 |
.001 |
.001 |
.003 |
.013 |
.001 |
.001 |
.001 |
.005 |
.04 |
.0 |
.022 |
.001 |
.015 |
.004 |
.001 |
.0 |
.001 |
.004 |
.001 |
.003 |
.003 |
.0 |
.002 |
.002 |
.036 |
.318 |
.005 |
.041 |
.0 |
.0 |
.0 |
.004 |
.001 |
.013 |
.0 |
.001 |
.0 |
.0 |
.014 |
.0 |
.007 |
.006 |
.004 |
.013 |
.0 |
.01 |
.306 |
.413 |
.562 |
.0 |
.0 |
.0 |
.001 |
.001 |
.0 |
.0 |
.0 |
.0 |
.001 |
.003 |
.006 |
.0 |
.0 |
.0 |
.004 |
.013 |
.001 |
.0 |
.0 |
.212 |
.001 |
.446 |
.023 |
.254 |
.009 |
.019 |
.0 |
.147 |
.0 |
.041 |
.055 |
.0 |
.0 |
.377 |
.007 |
.168 |
.005 |
.235 |
.0 |
.003 |
.0 |
.003 |
.25 |
.005 |
.021 |
.0 |
.993 |
.006 |
.097 |
.0 |
.0 |
.001 |
.0 |
.784 |
.001 |
.001 |
.162 |
.0 |
.0 |
.009 |
.0 |
.001 |
.0 |
.004 |
.0 |
.96 |
.278 |
.002 |
.003 |
.0 |
.145 |
.037 |
.001 |
.006 |
.007 |
.994 |
.992 |
.005 |
.0 |
.999 |
.993 |
.113 |
.001 |
.003 |
.998 |
|
Igf1r
|
Igf1r
|
Igf1r
|
Igf1r
|
Igf1r
|
Igf1r
|
Igf1r
|
Igf1r
|
Igf1r
|
Igf1r
|
Igf1r
|
Igf1r
|
Igf1r
|
Igf1r
|
Igf1r
|
Igf1r
|
Igf1r
|
Igf1r
|
Igf1r
|
Igf1r
|
Igf1r
|
Igf1r
|
Igf1r
|
Igf1r
|
Igf1r
|
Igf1r
|
Igf1r
|
Igf1r
|
Igf1r
|
Igf1r
|
Igf1r
|
Igf1r
|
Igf1r
|
Igf1r
|
Igf1r
|
Igf1r
|
Igf1r
|
Igf1r
|
Igf1r
|
Igf1r
|
Igf1r
|
Igf1r
|
Igf1r
|
Igf1r
|
Igf1r
|
Igf1r
|
Igf1r
|
Igf1r
|
Igf1r
|
Igf1r
|
Igf1r
|
Igf1r
|
Igf1r
|
Igf1r
|
Igf1r
|
Igf1r
|
Igf1r
|
Igf1r
|
Igf1r
|
Igf1r
|
Igf1r
|
Igf1r
|
Igf1r
|
Igf1r
|
Igf1r
|
Igf1r
|
Igf1r
|
Igf1r
|
Igf1r
|
Igf1r
|
Igf1r
|
Igf1r
|
Igf1r
|
Igf1r
|
Igf1r
|
Igf1r
|
Igf1r
|
Igf1r
|
Igf1r
|
Igf1r
|
Igf1r
|
Igf1r
|
Igf1r
|
Igf1r
|
Igf1r
|
Igf1r
|
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
|
- |
T |
A |
T |
A |
A |
T |
G |
A |
G |
5 |
C |
C |
A |
A |
G |
T |
A |
- |
G |
G |
C |
A |
C |
- |
G |
C |
A |
C |
A |
G |
G |
C |
T |
T |
C |
C |
T |
A |
C |
T |
- |
C |
C |
T |
T |
T |
G |
G |
T |
C |
T |
- |
A |
C |
G |
A |
G |
C |
A |
- |
A |
G |
A |
4 |
A |
A |
A |
A |
C |
A |
T |
- |
T |
- |
G |
T |
A |
A |
C |
C |
T |
T |
C |
A |
T |
T |
3 |
A |
G |
G |
C |
T |
T |
T |
T |
G |
C |
C |
C |
- |
C |
T |
C |
G |
A |
C |
T |
A |
C |
G |
- |
A |
C |
G |
- |
C |
T |
C |
C |
G |
T |
G |
C |
T |
T |
C |
C |
14 |
C |
C |
- |
T |
T |
C |
T |
A |
G |
A |
C |
A |
G |
C |
C |
T |
C |
G |
T |
- |
G |
C |
G |
G |
A |
C |
G |
A |
C |
C |
T |
- |
C |
C |
A |
A |
A |
C |
C |
G |
13 |
T |
A |
- |
C |
A |
T |
T |
C |
C |
A |
A |
A |
C |
G |
G |
T |
T |
8 |
G |
A |
T |
T |
T |
G |
C |
G |
- |
A |
A |
A |
C |
T |
A |
A |
G |
C |
G |
A |
A |
G |
C |
A |
G |
T |
G |
G |
A |
T |
- |
T |
- |
C |
A |
- |
C |
A |
C |
G |
A |
C |
C |
C |
G |
G |
A |
G |
A |
T |
A |
C |
T |
T |
C |
T |
- |
A |
C |
C |
- |
C |
- |
- |
- |
C |
A |
A |
A |
A |
A |
T |
A |
7 |
T |
C |
T |
- |
G |
A |
T |
G |
T |
A |
A |
A |
T |
G |
G |
C |
C |
- |
G |
A |
T |
G |
A |
A |
G |
C |
C |
C |
T |
- |
C |
C |
A |
- |
T |
G |
A |
- |
T |
G |
C |
T |
A |
G |
G |
T |
A |
A |
A |
C |
C |
C |
T |
- |
A |
A |
G |
- |
T |
T |
C |
C |
T |
A |
5 |
A |
T |
- |
G |
T |
A |
A |
T |
A |
- |
T |
- |
T |
C |
2 |
2 |
A |
C |
C |
A |
- |
C |
C |
A |
T |
C |
C |
T |
A |
- |
- |
C |
A |
T |
- |
- |
C |
A |
A |
C |
A |
- |
G |
- |
C |
- |
A |
A |
C |
A |
T |
- |
G |
T |
G |
C |
T |
C |
A |
G |
A |
C |
- |
T |
G |
T |
G |
A |
A |
C |
T |
C |
G |
C |
T |
C |
T |
A |
T |
T |
T |
C |
G |
C |
T |
G |
- |
C |
T |
T |
A |
G |
A |
C |
C |
- |
C |
A |
G |
A |
- |
A |
C |
A |
A |
G |
T |
A |
- |
A |
T |
A |
A |
G |
T |
T |
G |
C |
G |
2 |
G |
G |
G |
T |
T |
A |
C |
C |
G |
C |
T |
G |
T |
C |
4 |
C |
G |
C |
T |
A |
- |
C |
C |
G |
G |
T |
- |
T |
- |
2 |
G |
T |
G |
2 |
T |
A |
G |
G |
A |
A |
- |
- |
3 |
A |
T |
T |
G |
G |
G |
- |
- |
A |
T |
G |
A |
G |
G |
- |
T |
- |
G |
A |
2 |
- |
T |
G |
- |
- |
- |
- |
C |
G |
3 |
T |
A |
G |
C |
C |
42 |
A |
A |
T |
C |
7 |
C |
A |
C |
2 |
2 |
14 |
T |
A |
G |
8 |
T |
3 |
C |
C |
- |
G |
T |
- |
A |
T |
T |
C |
G |
- |
- |
G |
G |
G |
T |
3 |
- |
C |
A |
C |
T |
- |
2 |
4 |
A |
T |
G |
- |
- |
T |
C |
- |
- |
G |
C |
- |
G |
T |
G |
T |
- |
A |
T |
A |
A |
A |
T |
T |
G |
C |
A |
T |
C |
T |
- |
A |
T |
C |
G |
G |
C |
A |
- |
G |
A |
6 |
T |
A |
2 |
2 |
C |
A |
C |
C |
C |
T |
C |
A |
T |
T |
G |
- |
G |
G |
3 |
G |
- |
- |
G |
2 |
A |
4 |
- |
- |
C |
C |
A |
T |
G |
A |
- |
- |
G |
A |
T |
G |
G |
T |
- |
- |
C |
- |
C |
A |
A |
T |
A |
G |
T |
A |
G |
- |
124 |
- |
- |
T |
- |
- |
- |
- |
C |
C |
G |
T |
A |
T |
- |
4 |
A |
A |
A |
T |
A |
G |
6 |
A |
G |
C |
C |
C |
A |
- |
C |
G |
G |
C |
G |
T |
30 |
C |
T |
G |
A |
A |
A |
- |
G |
T |
G |
A |
A |
G |
G |
C |
A |
A |
T |
C |
G |
G |
G |
A |
C |
- |
A |
C |
45 |
T |
A |
- |
C |
A |
G |
- |
C |
3 |
T |
C |
T |
A |
A |
C |
G |
G |
A |
T |
T |
T |
2 |
G |
G |
C |
A |
- |
T |
T |
C |
- |
A |
A |
2 |
G |
G |
G |
G |
G |
T |
C |
- |
G |
C |
G |
T |
T |
C |
T |
C |
C |
A |
G |
A |
- |
T |
G |
A |
T |
A |
A |
A |
2 |
- |
T |
C |
C |
A |
- |
2 |
A |
A |
T |
C |
A |
G |
G |
C |
C |
T |
T |
A |
T |
15 |
G |
T |
G |
- |
A |
T |
A |
A |
121 |
A |
A |
T |
T |
G |
G |
T |
A |
A |
24 |
G |
C |
G |
C |
T |
T |
A |
T |
A |
A |
T |
A |
- |
2 |
C |
T |
T |
T |
C |
G |
A |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
3
|
C
|
T
|
C
|
G
|
G
|
A
|
A
|
C
|
A
|
-
|
T
|
A
|
G
|
G
|
A
|
C
|
G
|
2
|
A
|
A
|
T
|
-
|
T
|
C
|
A
|
T
|
G
|
T
|
T
|
C
|
A
|
T
|
C
|
C
|
A
|
T
|
C
|
G
|
T
|
C
|
A
|
T
|
T
|
C
|
C
|
G
|
C
|
A
|
C
|
G
|
C
|
3
|
G
|
A
|
A
|
G
|
C
|
G
|
G
|
C
|
G
|
A
|
G
|
-
|
G
|
T
|
G
|
G
|
G
|
G
|
A
|
T
|
C
|
G
|
A
|
C
|
G
|
G
|
A
|
A
|
C
|
A
|
T
|
G
|
C
|
C
|
-
|
G
|
A
|
A
|
T
|
C
|
C
|
G
|
C
|
C
|
T
|
T
|
T
|
C
|
-
|
-
|
-
|
-
|
-
|
T
|
-
|
-
|
-
|
-
|
2
|
-
|
-
|
-
|
T
|
T
|
A
|
A
|
G
|
A
|
C
|
T
|
T
|
C
|
G
|
T
|
T
|
-
|
T
|
T
|
11
|
C
|
C
|
G
|
-
|
G
|
A
|
T
|
T
|
T
|
T
|
-
|
T
|
A
|
T
|
A
|
C
|
19
|
A
|
T
|
A
|
A
|
A/T
|
C/T
|
G/T
|
A/C
|
A
|
G
|
A
|
C
|
T
|
T
|
G
|
T
|
C
|
T
|
A
|
A
|
-
|
C
|
G
|
2
|
T
|
G
|
G
|
C
|
-
|
T
|
G
|
G
|
G
|
T
|
A
|
A
|
C
|
G
|
-
|
T
|
G
|
A
|
A
|
A
|
C
|
T
|
-
|
G
|
G
|
-
|
G
|
G
|
C
|
G
|
G
|
A
|
T
|
T
|
G
|
G
|
A
|
T
|
G
|
A
|
C
|
T
|
A
|
G
|
C
|
C
|
C
|
G
|
T
|
-
|
T
|
T
|
T
|
T
|
A
|
G
|
C/G
|
C/G
|
T
|
A
|
A
|
C
|
A
|
G
|
C
|
-
|
G
|
A
|
G
|
T
|
C
|
T
|
G
|
T
|
A
|
C
|
G
|
G
|
3
|
C
|
T
|
C
|
C
|
C
|
C
|
G
|
C
|
C
|
-
|
C
|
T
|
C
|
10
|
C
|
T
|
C
|
T
|
C
|
G
|
G
|
G
|
C
|
T
|
A
|
T
|
A
|
A
|
A
|
G
|
A
|
A
|
G
|
G
|
A
|
T
|
G
|
A
|
A
|
34
|
T
|
G
|
T
|
30
|
C
|
C
|
G
|
7
|
C
|
C
|
T
|
A
|
G
|
A
|
A
|
C
|
G
|
C
|
T
|
T
|
T
|
T
|
C
|
A
|
G
|
G
|
A
|
T
|
C
|
C
|
T
|
T
|
C
|
-
|
-
|
G
|
C
|
T
|
A
|
C
|
-
|
T
|
G
|
C
|
4
|
G
|
T
|
-
|
T
|
-
|
-
|
G
|
T
|
T
|
G
|
T
|
T
|
T
|
C
|
G
|
T
|
T
|
C
|
G
|
5
|
3
|
A
|
G
|
A
|
3
|
T
|
T
|
G
|
G
|
T
|
G
|
4
|
A
|
4
|
G
|
C
|
G
|
G
|
T
|
-
|
-
|
109
|
A
|
G
|
A
|
T
|
C
|
G
|
G
|
A
|
G
|
T
|
A
|
C
|
A
|
C
|
C
|
T
|
T
|
T
|
C
|
T
|
A
|
T
|
C
|
T
|
C
|
G
|
A
|
C
|
C
|
T
|
C
|
T
|
C
|
C
|
3
|
T
|
G
|
C
|
T
|
A
|
G
|
T
|
T
|
5
|
-
|
G
|
C
|
G
|
A
|
C
|
T
|
T
|
C
|
T
|
C
|
G
|
4
|
T
|
C
|
C
|
G
|
A
|
C
|
C
|
A
|
T
|
T
|
-
|
T
|
A
|
A
|
C
|
A
|
G
|
T
|
T
|
C
|
T
|
G
|
C
|
C
|
G
|
-
|
A
|
C
|
T
|
C
|
G
|
G
|
A
|
T
|
T
|
T
|
C
|
G
|
-
|
G
|
-
|
-
|
-
|
-
|
-
|
-
|
-
|
-
|
A
|
-
|
-
|
A
|
G
|
-
|
-
|
A
|
-
|
-
|
C
|
-
|
C
|
A
|
-
|
C
|
-
|
-
|
-
|
-
|
2
|
G
|
A
|
-
|
-
|
-
|
T
|
G
|
T
|
T
|
3
|
G
|
C/C
|
A
|
-
|
-
|
C
|
G
|
A
|
T
|
T
|
-
|
T
|
G
|
A
|
T
|
-
|
T
|
C
|
A
|
-
|
-
|
-
|
C
|
G
|
T
|
8/-
|
T/-
|
3/-
|
G
|
G
|
C
|
A
|
G
|
A
|
-
|
-
|
A
|
-
|
-
|
C
|
T
|
-
|
-
|
-
|
-
|
-
|
A
|
-
|
C
|
T
|
C
|
C
|
-
|
-
|
-
|
-
|
-
|
T
|
A
|
C
|
T
|
G
|
2
|
-
|
-
|
G
|
-
|
-
|
-
|
A
|
A
|
G
|
C
|
T
|
G
|
G
|
C
|
C
|
A
|
T
|
T
|
A
|
T
|
C
|
G
|
-
|
C
|
T
|
A
|
A
|
A
|
G
|
2
|
A
|
G
|
-
|
C
|
C
|
-
|
-
|
T
|
G
|
T
|
A
|
A
|
C
|
T
|
G
|
C
|
C
|
A
|
A
|
C
|
A
|
-
|
A
|
2
|
C
|
-
|
-
|
C
|
-
|
C
|
9
|
G
|
G
|
G
|
-
|
C
|
G
|
T
|
31
|
A
|
G
|
C
|
C
|
A
|
C
|
9
|
C
|
-
|
A
|
T
|
G
|
-
|
C
|
G
|
T
|
G
|
-
|
A
|
G
|
124/-
|
A
|
T
|
-
|
A
|
18
|
2
|
30
|
T
|
T
|
A
|
C
|
G
|
C
|
2
|
-
|
G
|
C
|
G
|
-
|
T
|
A
|
-
|
G
|
A
|
T
|
T
|
A
|
G
|
A
|
T
|
C
|
A
|
T
|
A
|
C
|
-
|
T
|
C
|
A
|
G
|
G
|
G
|
16
|
A
|
C
|
A
|
T
|
G
|
A
|
A
|
T
|
T
|
C
|
G
|
T
|
A
|
C
|
A
|
G
|
G
|
2
|
C
|
T
|
-
|
G
|
-
|
2
|
-
|
T
|
T
|
T
|
T
|
-
|
-
|
-
|
-
|
-
|
-
|
T
|
A
|
A
|
G
|
C
|
C
|
-
|
-
|
A
|
T
|
T
|
G
|
C
|
G
|
C
|
T
|
4
|
G
|
G
|
-
|
A
|
A
|
G/A
|
G/C
|
A
|
G
|
T
|
-/T
|
A
|
T
|
A
|
C
|
C
|
T
|
C
|
T
|
G
|
G
|
A
|
G
|
13
|
C
|
A
|
G
|
C
|
G
|
C
|
G
|
-
|
6
|
-
|
T
|
G
|
G
|
2
|
-
|
G
|
G
|
A
|
G
|
G
|
A
|
A
|
T
|
T
|
C
|
G
|
G
|
A
|
-
|
A
|
C
|
A
|
7
|
G
|
C
|
G
|
G
|
121/-
|
G
|
G
|
C
|
C
|
T
|
A
|
C
|
G
|
G
|
-
|
A
|
T
|
A
|
T
|
G
|
C
|
G
|
-
|
G
|
T
|
C
|
G
|
T
|
-
|
T
|
C
|
A
|
C
|
-
|
T
|
-
|
|