|
.0 |
.0 |
.1 |
.0 |
.022 |
.0 |
.013 |
.007 |
.004 |
.001 |
.001 |
.134 |
.036 |
.006 |
.008 |
.019 |
-- |
.082 |
.038 |
.001 |
.065 |
.015 |
.015 |
.001 |
.004 |
.943 |
.391 |
.003 |
.0 |
.017 |
.008 |
.009 |
-- |
-- |
.0 |
.0 |
.001 |
.001 |
.03 |
.0 |
.002 |
.01 |
.002 |
.003 |
.055 |
.0 |
.0 |
.01 |
.002 |
.046 |
.124 |
.054 |
-- |
-- |
.0 |
.003 |
.003 |
.072 |
.917 |
.011 |
.0 |
-- |
-- |
.041 |
.005 |
.871 |
.0 |
.0 |
.0 |
.0 |
.016 |
.022 |
.009 |
.003 |
.016 |
.492 |
.001 |
.418 |
.072 |
.002 |
.001 |
.023 |
.001 |
.0 |
.001 |
.004 |
.012 |
.009 |
.011 |
.0 |
.009 |
.003 |
.04 |
.023 |
.008 |
.195 |
.008 |
.012 |
.0 |
.001 |
.0 |
.292 |
.074 |
.006 |
.001 |
.204 |
.005 |
.0 |
.038 |
.0 |
.001 |
.019 |
.008 |
.017 |
.01 |
.011 |
.005 |
.003 |
.001 |
.046 |
.173 |
.008 |
.004 |
.021 |
.013 |
.021 |
.006 |
.016 |
.111 |
.001 |
.0 |
.0 |
.784 |
.001 |
.007 |
.0 |
.02 |
.005 |
.0 |
.0 |
.025 |
.005 |
.129 |
.005 |
.004 |
.59 |
.003 |
.06 |
.022 |
.077 |
.593 |
.001 |
.011 |
.823 |
.025 |
.023 |
.0 |
.01 |
.0 |
.001 |
.024 |
.046 |
.002 |
.914 |
.945 |
.138 |
.002 |
.0 |
.0 |
.001 |
.178 |
.001 |
.037 |
.005 |
.023 |
.241 |
.089 |
.225 |
.177 |
.353 |
.008 |
.887 |
.025 |
-- |
-- |
.033 |
.007 |
.002 |
.018 |
.015 |
.483 |
.0 |
.002 |
.1 |
.022 |
.023 |
.005 |
.001 |
.007 |
.002 |
.043 |
.003 |
.097 |
.002 |
.113 |
.003 |
.489 |
.509 |
.188 |
.003 |
.03 |
.034 |
.176 |
.004 |
.022 |
.021 |
.001 |
.004 |
-- |
.001 |
.002 |
.0 |
.02 |
.007 |
.027 |
.003 |
.0 |
.033 |
.003 |
.065 |
.001 |
.196 |
.049 |
.912 |
.055 |
.014 |
.019 |
.206 |
.076 |
.077 |
.008 |
.03 |
.349 |
.009 |
.226 |
.021 |
.511 |
.313 |
-- |
.006 |
.037 |
.034 |
.033 |
.006 |
.028 |
.017 |
.013 |
.013 |
.002 |
.024 |
.004 |
.0 |
.055 |
.065 |
.001 |
.002 |
.039 |
-- |
.0 |
.034 |
.0 |
.015 |
.002 |
.0 |
.049 |
.083 |
.0 |
.0 |
-- |
.0 |
.0 |
.152 |
.002 |
.01 |
.223 |
.032 |
.192 |
.0 |
.545 |
.001 |
.0 |
.0 |
.0 |
.001 |
.019 |
.01 |
.004 |
.028 |
.0 |
.031 |
.004 |
.0 |
.084 |
.006 |
.02 |
.002 |
.001 |
.007 |
.29 |
.001 |
.997 |
.996 |
.003 |
.001 |
.009 |
.088 |
.003 |
.015 |
.862 |
.004 |
.027 |
.927 |
.052 |
.094 |
.321 |
.022 |
.006 |
.191 |
.008 |
.176 |
.002 |
.005 |
.022 |
.178 |
.001 |
.17 |
.001 |
.0 |
.005 |
-- |
-- |
-- |
-- |
.123 |
.007 |
.849 |
.099 |
.107 |
.006 |
.017 |
.001 |
.085 |
.03 |
.0 |
.026 |
.16 |
.013 |
.007 |
.002 |
-- |
.075 |
.049 |
.345 |
.032 |
.013 |
.033 |
.012 |
.338 |
.01 |
.047 |
.0 |
.001 |
.0 |
.008 |
.0 |
.0 |
.983 |
.044 |
.153 |
-- |
.014 |
.353 |
.119 |
.017 |
.734 |
.996 |
.988 |
.08 |
.013 |
.021 |
.003 |
.999 |
.035 |
.005 |
.001 |
.124 |
.007 |
.008 |
.001 |
.008 |
.072 |
.001 |
.003 |
.912 |
.024 |
.258 |
.098 |
.007 |
.004 |
.007 |
.002 |
.003 |
.024 |
.003 |
.002 |
.703 |
.0 |
.003 |
.0 |
.002 |
.1 |
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
Casp6-ps2
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
|
Erc1
|
Erc1
|
Erc1
|
Erc1
|
Erc1
|
Erc1
|
Erc1
|
Erc1
|
Erc1
|
Erc1
|
Erc1
|
Erc1
|
Erc1
|
Erc1
|
Erc1
|
Erc1
|
Erc1
|
Erc1
|
Erc1
|
Erc1
|
Erc1
|
Erc1
|
Erc1
|
Erc1
|
Erc1
|
Erc1
|
Erc1
|
Erc1
|
Erc1
|
Erc1
|
Erc1
|
Erc1
|
Erc1
|
Erc1
|
Erc1
|
Erc1
|
Erc1
|
Erc1
|
Erc1
|
Erc1
|
Erc1
|
Erc1
|
Erc1
|
|
G |
A |
C |
C |
T |
C |
G |
T |
T |
G |
C |
G |
C |
G |
T |
C |
T |
A |
T |
A |
A |
A |
T |
T |
T |
C |
T |
G |
T |
C |
G |
C |
C |
C |
T |
C |
C |
T |
G |
C |
T |
T |
T |
A |
C |
A |
G |
A |
C |
C |
T |
G |
T |
T |
C |
A |
A |
C |
C |
C |
T |
C |
C |
T |
G |
T |
C |
G |
C |
G |
C |
C |
C |
A |
T |
C |
G |
C |
A |
G |
G |
A |
C |
A |
A |
G |
G |
G |
T |
G |
C |
C |
T |
G |
C |
G |
G |
T |
T |
T |
A |
T |
T |
T |
G |
C |
G |
T |
C |
T |
A |
T |
C |
T |
T |
C |
G |
T |
G |
T |
G |
C |
T |
T |
C |
T |
T |
G |
T |
T |
C |
G |
C |
T |
G |
T |
G |
C |
T |
C |
C |
A |
A |
A |
T |
A |
A |
G |
T |
T |
A |
A |
A |
C |
T |
T |
G |
G |
C |
C |
T |
T |
T |
G |
G |
A |
A |
T |
C |
A |
C |
T |
A |
T |
T |
T |
C |
G |
T |
G |
T |
G |
G |
A |
A |
A |
C |
T |
G |
T |
T |
A |
A |
A |
C |
G |
G |
C |
C |
T |
G |
G |
G |
A |
A |
A |
G |
T |
A |
C |
A |
T |
C |
T |
C |
A |
T |
C |
T |
G |
T |
T |
T |
T |
T |
T |
G |
A |
C |
C |
G |
T |
C |
A |
C |
A |
T |
G |
C |
A |
A |
G |
A |
A |
G |
A |
C |
A |
A |
T |
G |
G |
A |
T |
G |
C |
G |
T |
G |
T |
T |
A |
A |
A |
G |
A |
T |
G |
A |
T |
C |
G |
A |
G |
G |
A |
C |
G |
A |
A |
C |
C |
C |
G |
T |
G |
T |
G |
G |
A |
A |
T |
C |
C |
A |
T |
T |
A |
A |
A |
G |
T |
T |
C |
T |
A |
A |
A |
G |
T |
A |
A |
G |
T |
G |
C |
G |
C |
C |
G |
C |
C |
T |
A |
A |
A |
A |
A |
C |
G |
G |
C |
C |
A |
C |
G |
T |
A |
A |
T |
G |
C |
G |
G |
A |
C |
C |
G |
A |
C |
A |
C |
G |
T |
C |
T |
T |
C |
T |
T |
A |
G |
G |
A |
C |
G |
C |
T |
A |
C |
C |
A |
T |
T |
G |
A |
A |
G |
C |
A |
C |
C |
G |
A |
C |
T |
C |
G |
T |
C |
T |
G |
C |
C |
C |
G |
C |
A |
G |
G |
T |
T |
T |
C |
G |
G |
A |
G |
C |
G |
C |
C |
A |
G |
G |
C |
G |
G |
G |
C |
C |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
A
|
G
|
T
|
T
|
C
|
A
|
A
|
C
|
C
|
A
|
T
|
A
|
T
|
A
|
G
|
T
|
C
|
T
|
C
|
G
|
G
|
G
|
C
|
C
|
C
|
T
|
C
|
C
|
C
|
T
|
A
|
T
|
T
|
T
|
C
|
T
|
G
|
C
|
A
|
T
|
G
|
C
|
A
|
G
|
T
|
G
|
A
|
G
|
T
|
T
|
C
|
T
|
C
|
C
|
G
|
C
|
G
|
G
|
G
|
T
|
A
|
T
|
T
|
C
|
A
|
A
|
T
|
T
|
T
|
A
|
T
|
T
|
T
|
G
|
C
|
T
|
A
|
T
|
C
|
A
|
T
|
G
|
T
|
T
|
G
|
A
|
A
|
A
|
C
|
A
|
T
|
A
|
C
|
A
|
T
|
T
|
C
|
C
|
C
|
A
|
G
|
A
|
A
|
C
|
A
|
G
|
A
|
C
|
T
|
C
|
C
|
A
|
A
|
A
|
C
|
T
|
A
|
C
|
A
|
C
|
A
|
A
|
G
|
G
|
T
|
C
|
C
|
A
|
C
|
G
|
T
|
A
|
A
|
C
|
A
|
G
|
T
|
G
|
C
|
T
|
T
|
G
|
T
|
G
|
A
|
G
|
T
|
A
|
A
|
C
|
T
|
G
|
C
|
T
|
C
|
A
|
A
|
A
|
T
|
T
|
C
|
C
|
C
|
A
|
A
|
T
|
G
|
C
|
T
|
G
|
T
|
C
|
C
|
C
|
C
|
C
|
A
|
A
|
C
|
C
|
C
|
T
|
A
|
T
|
C
|
G
|
T
|
C
|
A
|
C
|
C
|
T
|
G
|
G
|
T
|
C
|
A
|
T
|
A
|
A
|
T
|
C
|
A
|
G
|
G
|
T
|
A
|
C
|
G
|
T
|
C
|
C
|
G
|
C
|
A
|
G
|
C
|
G
|
C
|
A
|
C
|
C
|
C
|
C
|
C
|
C
|
C
|
G
|
T
|
T
|
A
|
C
|
A
|
G
|
T
|
G
|
C
|
A
|
G
|
G
|
T
|
A
|
T
|
C
|
A
|
G
|
T
|
G
|
G
|
C
|
A
|
A
|
G
|
C
|
A
|
T
|
A
|
C
|
C
|
C
|
C
|
G
|
G
|
G
|
C
|
G
|
C
|
T
|
G
|
C
|
T
|
T
|
T
|
A
|
A
|
G
|
G
|
C
|
G
|
T
|
G
|
T
|
T
|
A
|
G
|
A
|
C
|
A
|
A
|
G
|
G
|
C
|
T
|
T
|
G
|
C
|
C
|
C
|
G
|
G
|
T
|
C
|
C
|
A
|
A
|
C
|
G
|
G
|
A
|
C
|
G
|
G
|
A
|
A
|
T
|
G
|
T
|
T
|
T
|
A
|
T
|
T
|
C
|
G
|
G
|
G
|
G
|
G
|
T
|
A
|
A
|
T
|
A
|
G
|
T
|
C
|
C
|
G
|
G
|
G
|
A
|
A
|
T
|
A
|
C
|
T
|
T
|
A
|
C
|
T
|
G
|
T
|
A
|
C
|
A
|
A
|
C
|
T
|
G
|
C
|
C
|
A
|
A
|
T
|
G
|
A
|
A
|
C
|
G
|
T
|
A
|
C
|
C
|
C
|
A
|
G
|
G
|
A
|
T
|
C
|
T
|
G
|
C
|
C
|
A
|
C
|
T
|
A
|
A
|
T
|
C
|
A
|
T
|
G
|
T
|
A
|
A
|
G
|
A
|
A
|
C
|
C
|
G
|
T
|
A
|
A
|
C
|
T
|
T
|
A
|
T
|
T
|
T
|
A
|
T
|
T
|
A
|
A
|
T
|
T
|
A
|
|