|
.001 |
.001 |
.002 |
.001 |
.002 |
.0 |
.005 |
.003 |
.005 |
.018 |
.001 |
.009 |
.885 |
.812 |
.441 |
.001 |
.0 |
.002 |
.0 |
.0 |
.235 |
.0 |
.003 |
.0 |
.003 |
.0 |
.001 |
.019 |
.0 |
.0 |
.001 |
.002 |
.0 |
.001 |
.001 |
.0 |
.0 |
.0 |
.0 |
.0 |
.0 |
.0 |
.001 |
-- |
-- |
-- |
.043 |
.001 |
.001 |
.0 |
.0 |
.018 |
.001 |
.002 |
.0 |
.0 |
.001 |
.0 |
.001 |
.995 |
.001 |
.709 |
.003 |
.0 |
.002 |
.0 |
.001 |
.009 |
.001 |
.001 |
.003 |
.459 |
.531 |
.491 |
.0 |
.001 |
.002 |
.015 |
.0 |
.001 |
.0 |
.026 |
.0 |
.0 |
.0 |
.001 |
.004 |
.001 |
.0 |
.002 |
.001 |
.0 |
.001 |
.0 |
.0 |
.001 |
.001 |
.0 |
.001 |
.003 |
.998 |
.001 |
.0 |
.012 |
.002 |
.001 |
.002 |
.033 |
.0 |
.002 |
.044 |
.324 |
.002 |
.007 |
.001 |
.0 |
.0 |
1.0 |
.0 |
.014 |
.008 |
.015 |
.003 |
.013 |
.002 |
1.0 |
.0 |
.002 |
.001 |
1.0 |
.232 |
.427 |
.045 |
.021 |
.0 |
.001 |
.0 |
.006 |
.0 |
.002 |
.105 |
.001 |
.012 |
.0 |
.429 |
.011 |
.0 |
.0 |
.002 |
.001 |
.995 |
.99 |
.774 |
.0 |
.416 |
.001 |
.038 |
.0 |
.004 |
.006 |
.001 |
.001 |
.0 |
.007 |
.001 |
.14 |
.029 |
.057 |
.001 |
.001 |
.0 |
.001 |
.0 |
.001 |
.005 |
.0 |
.0 |
.001 |
.001 |
.0 |
.986 |
.829 |
.001 |
.017 |
.005 |
.0 |
.0 |
.568 |
.0 |
.004 |
.0 |
.001 |
.0 |
.0 |
.076 |
.008 |
.0 |
.003 |
.0 |
.008 |
.007 |
.0 |
.0 |
.0 |
.0 |
.001 |
.006 |
.002 |
.0 |
.044 |
.0 |
.019 |
.768 |
1.0 |
.488 |
.0 |
.012 |
.001 |
.006 |
.007 |
.004 |
.0 |
.0 |
.001 |
.952 |
.002 |
-- |
.017 |
.019 |
.001 |
.307 |
.084 |
.058 |
.0 |
.012 |
.006 |
.047 |
.182 |
.0 |
.0 |
.0 |
.001 |
.001 |
.029 |
.004 |
.0 |
.047 |
.0 |
.0 |
.0 |
.032 |
.0 |
.022 |
.001 |
.007 |
.0 |
.007 |
.0 |
.0 |
.0 |
.004 |
.0 |
.0 |
.001 |
.92 |
.003 |
.059 |
.015 |
.0 |
.096 |
.143 |
.0 |
.005 |
.0 |
.0 |
.0 |
.0 |
.009 |
.003 |
.001 |
.013 |
.0 |
.329 |
.885 |
.005 |
.004 |
1.0 |
.001 |
.007 |
.033 |
.0 |
.0 |
.0 |
.002 |
.104 |
.0 |
.717 |
.001 |
.084 |
.0 |
.052 |
.296 |
.003 |
.014 |
.002 |
.0 |
.015 |
.001 |
.003 |
.002 |
.005 |
.073 |
.001 |
.0 |
.06 |
.006 |
.003 |
.006 |
.001 |
.027 |
.001 |
.0 |
.005 |
.16 |
.324 |
.0 |
.0 |
.002 |
.005 |
.001 |
.003 |
.008 |
.001 |
.0 |
.0 |
-- |
.076 |
.325 |
.002 |
.0 |
.0 |
.002 |
.012 |
.014 |
.147 |
.0 |
.0 |
.0 |
.0 |
.0 |
.001 |
.0 |
.0 |
.001 |
.001 |
.003 |
.0 |
.002 |
.193 |
.0 |
.001 |
.447 |
.001 |
.001 |
.01 |
.007 |
.0 |
.0 |
.0 |
.007 |
.0 |
.0 |
.001 |
.01 |
.0 |
.0 |
-- |
-- |
.004 |
.0 |
.002 |
.0 |
.041 |
.0 |
.002 |
.0 |
.0 |
.001 |
.003 |
.027 |
.001 |
.84 |
.0 |
.001 |
.0 |
.004 |
.0 |
.0 |
.0 |
.001 |
.0 |
.26 |
.037 |
.1 |
.0 |
.0 |
.286 |
.002 |
.0 |
.665 |
.001 |
.0 |
.0 |
.002 |
.089 |
.062 |
.001 |
.001 |
.001 |
.0 |
.008 |
.0 |
.286 |
.002 |
.003 |
.001 |
.001 |
.34 |
.172 |
.0 |
.003 |
.0 |
.025 |
.015 |
.001 |
.242 |
.044 |
.003 |
.0 |
.129 |
.756 |
.003 |
.02 |
.137 |
.0 |
.001 |
.0 |
.0 |
.002 |
.0 |
.005 |
.315 |
.0 |
.002 |
.13 |
.016 |
.016 |
.0 |
.003 |
.128 |
.0 |
.084 |
.0 |
.002 |
.006 |
.0 |
.002 |
.287 |
.228 |
.01 |
.003 |
.115 |
.005 |
.121 |
.999 |
.922 |
.0 |
.0 |
.0 |
.001 |
.0 |
.0 |
.18 |
.025 |
.001 |
.0 |
.491 |
.002 |
.001 |
.843 |
.065 |
.0 |
.0 |
.451 |
.993 |
.0 |
.0 |
.126 |
.003 |
.0 |
.026 |
.1 |
.001 |
.004 |
.029 |
.029 |
.003 |
.014 |
.006 |
.0 |
.005 |
.0 |
.0 |
.01 |
.002 |
.0 |
.0 |
.001 |
.001 |
.003 |
.041 |
.001 |
.0 |
.0 |
.01 |
.001 |
.107 |
.001 |
.0 |
.0 |
.842 |
.001 |
.002 |
.0 |
.0 |
.0 |
.008 |
.035 |
.0 |
.0 |
.002 |
.001 |
.008 |
.0 |
.001 |
.0 |
.0 |
.0 |
.0 |
.002 |
.504 |
.092 |
.076 |
.196 |
.294 |
.941 |
.003 |
.003 |
.002 |
.065 |
.002 |
.016 |
.002 |
.107 |
.004 |
.773 |
.76 |
.0 |
.94 |
.008 |
.002 |
.002 |
.028 |
.99 |
.115 |
.003 |
.003 |
.014 |
.033 |
.049 |
.002 |
.004 |
.005 |
.001 |
.002 |
.002 |
.003 |
.028 |
.029 |
.047 |
.134 |
.027 |
.008 |
.001 |
.001 |
-- |
-- |
-- |
-- |
.004 |
.35 |
.082 |
.0 |
.179 |
.001 |
.0 |
.001 |
.001 |
.008 |
.003 |
.0 |
.018 |
.033 |
-- |
.025 |
.051 |
.015 |
.127 |
.069 |
.045 |
.046 |
.036 |
.055 |
.006 |
.017 |
.144 |
.107 |
.297 |
.013 |
.031 |
.108 |
.107 |
.053 |
.033 |
-- |
-- |
-- |
.002 |
.167 |
.043 |
.036 |
.001 |
.13 |
.017 |
.055 |
.004 |
.002 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
.003 |
.005 |
.131 |
.041 |
.078 |
.2 |
.141 |
.005 |
.027 |
.002 |
.01 |
.001 |
.0 |
.025 |
.001 |
.0 |
.043 |
.0 |
.002 |
.002 |
.001 |
.012 |
.18 |
.013 |
.0 |
.005 |
.0 |
.003 |
.082 |
.003 |
.015 |
.0 |
.0 |
.001 |
.031 |
.001 |
.049 |
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
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--
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--
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--
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--
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--
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--
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--
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--
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--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
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--
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--
|
--
|
--
|
--
|
--
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--
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--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
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--
|
--
|
--
|
--
|
--
|
--
|
--
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--
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--
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--
|
--
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--
|
--
|
--
|
--
|
--
|
--
|
--
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--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
Insyn2b
|
Insyn2b
|
Insyn2b
|
Insyn2b
|
Insyn2b
|
Insyn2b
|
Insyn2b
|
Insyn2b
|
Insyn2b
|
Insyn2b
|
Insyn2b
|
Insyn2b
|
Insyn2b
|
Insyn2b
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
|
Dock2
|
Dock2
|
Dock2
|
Dock2
|
Dock2
|
Dock2
|
Dock2
|
Dock2
|
Dock2
|
Dock2
|
Dock2
|
Dock2
|
Dock2
|
Dock2
|
Dock2
|
Dock2
|
Dock2
|
Dock2
|
Dock2
|
Dock2
|
Dock2
|
Dock2
|
Dock2
|
Dock2
|
Dock2
|
Dock2
|
Dock2
|
Dock2
|
Dock2
|
Dock2
|
Dock2
|
Dock2
|
Dock2
|
Dock2
|
Dock2
|
Dock2
|
Dock2
|
Dock2
|
Dock2
|
Dock2
|
Dock2
|
Dock2
|
Dock2
|
Dock2
|
Dock2
|
Dock2
|
Dock2
|
Dock2
|
Dock2
|
Dock2
|
Dock2
|
Dock2
|
Dock2
|
Dock2
|
Dock2
|
Dock2
|
Dock2
|
Dock2
|
Dock2
|
Dock2
|
Dock2
|
Dock2
|
Dock2
|
Dock2
|
Dock2
|
Dock2
|
Dock2
|
Dock2
|
Dock2
|
Dock2
|
|
C |
A |
G |
T |
G |
G |
A |
C |
A |
G |
G |
G |
T |
A |
G |
G |
T |
G |
C |
G |
G |
C |
A |
C |
T |
T |
G |
A |
C |
T |
T |
C |
T |
T |
G |
T |
A |
G |
C |
C |
A |
G |
A |
C |
G |
T |
A |
G |
C |
T |
T |
A |
A |
T |
T |
G |
G |
G |
C |
G |
C |
T |
T |
C |
G |
G |
T |
C |
C |
T |
A |
T |
T |
G |
T |
T |
G |
C |
G |
G |
G |
A |
A |
C |
G |
G |
G |
C |
G |
G |
G |
C |
A |
T |
G |
A |
G |
T |
C |
T |
C |
T |
T |
A |
C |
C |
T |
G |
G |
A |
C |
C |
T |
C |
T |
C |
C |
A |
C |
T |
G |
C |
G |
T |
A |
G |
T |
A |
G |
C |
G |
G |
G |
G |
G |
T |
C |
G |
A |
T |
T |
C |
C |
A |
A |
C |
A |
C |
T |
T |
C |
G |
T |
C |
C |
A |
G |
T |
C |
A |
G |
A |
T |
G |
A |
A |
T |
C |
C |
G |
C |
G |
C |
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G
|
A
|
C
|
G
|
A
|
G
|
T
|
A
|
A
|
T
|
G
|
G
|
T
|
T
|
T
|
C
|
A
|
A
|
T
|
T
|
A
|
T
|
T
|
A
|
C
|
T
|
A
|
|