|
.0 |
.002 |
.004 |
.223 |
.001 |
.34 |
.867 |
.058 |
.463 |
.188 |
-- |
-- |
-- |
-- |
.333 |
.059 |
.003 |
.002 |
.006 |
.047 |
.003 |
.014 |
-- |
-- |
.531 |
.115 |
-- |
.001 |
.013 |
.015 |
.001 |
.0 |
.007 |
.76 |
.006 |
.004 |
.013 |
.0 |
.006 |
.005 |
.0 |
.001 |
.003 |
.089 |
.163 |
.009 |
.014 |
.009 |
.588 |
.024 |
.2 |
.099 |
.143 |
.03 |
.123 |
.009 |
.0 |
.0 |
.009 |
.001 |
.006 |
.0 |
.02 |
.101 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
.045 |
.293 |
.22 |
.128 |
.004 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
.058 |
.156 |
.954 |
.03 |
.133 |
.134 |
.134 |
.133 |
.132 |
.126 |
.11 |
.0 |
.013 |
1.0 |
.965 |
.0 |
.084 |
.107 |
.001 |
.084 |
.438 |
.974 |
.972 |
.201 |
.295 |
.27 |
.002 |
.002 |
.001 |
.001 |
.953 |
.408 |
.952 |
.082 |
.003 |
.25 |
.088 |
.017 |
.109 |
.586 |
-- |
.017 |
.003 |
.156 |
.068 |
.002 |
.001 |
.001 |
.002 |
.506 |
.091 |
.024 |
.001 |
.025 |
.023 |
.019 |
.049 |
.002 |
.074 |
.006 |
.025 |
.003 |
.018 |
.063 |
.388 |
.003 |
.005 |
.145 |
.234 |
.003 |
.012 |
.007 |
-- |
-- |
.441 |
.023 |
.013 |
.013 |
.057 |
.002 |
.022 |
.014 |
.046 |
.04 |
.001 |
.003 |
.278 |
.001 |
.017 |
.045 |
.006 |
.057 |
.0 |
.002 |
.008 |
.0 |
.62 |
.028 |
.002 |
.031 |
.724 |
.021 |
.086 |
.143 |
.039 |
.001 |
.047 |
.001 |
.973 |
.031 |
.035 |
.018 |
-- |
-- |
.011 |
.061 |
.004 |
.023 |
.003 |
.012 |
.029 |
.002 |
.014 |
.523 |
.099 |
.0 |
.017 |
.139 |
.013 |
.003 |
.0 |
.015 |
.101 |
.293 |
.008 |
.004 |
.001 |
.003 |
.001 |
.001 |
.522 |
.0 |
|
Cdk19
|
Cdk19
|
Cdk19
|
Cdk19
|
Cdk19
|
Cdk19
|
Cdk19
|
Cdk19
|
Cdk19
|
Cdk19
|
Cdk19
|
Cdk19
|
Cdk19
|
Cdk19
|
Cdk19
|
Cdk19
|
Cdk19
|
Cdk19
|
Cdk19
|
Cdk19
|
Cdk19
|
Cdk19
|
Cdk19
|
Cdk19
|
Cdk19
|
Cdk19
|
Cdk19
|
Cdk19
|
Cdk19
|
Cdk19
|
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
|
C |
G |
C |
G |
T |
T |
2 |
19 |
- |
A |
C |
G |
A |
- |
C |
G |
G |
C |
G |
C |
T |
T |
A |
G |
G |
T |
24 |
- |
G |
C |
A |
C |
A |
G |
G |
- |
G |
C |
G |
A |
T |
T |
A |
C |
A |
T |
T |
T |
T |
- |
C |
T |
- |
G |
4 |
C |
A |
C |
G |
6 |
G |
G |
C |
A |
C |
A |
G |
C |
C |
A |
T |
T |
G |
T |
T |
C |
A |
A |
C |
A |
T |
- |
G |
T |
G |
C |
C |
G |
G |
G |
G |
4 |
- |
A |
C |
C |
G |
C |
C |
T |
A |
G |
T |
C |
A |
A |
C |
A |
C |
T |
G |
A |
T |
A |
C |
T |
G |
T |
C |
A |
A |
C |
G |
A |
G |
T |
A |
A |
T |
C |
T |
A |
T |
A |
C |
T |
- |
G |
A |
G |
G |
G |
A |
T |
T |
C |
A |
T |
G |
G |
A |
2 |
A |
A |
G |
A |
G |
A |
A |
A |
A |
A |
A |
G |
T |
G |
C |
C |
- |
A |
G |
20 |
- |
2 |
34 |
C |
3 |
30 |
G |
T |
T |
G |
G |
G |
T |
- |
T |
C |
T |
T |
T |
C |
2 |
A |
C |
G |
G |
C |
A |
T |
T |
- |
A |
T |
C |
A |
A |
A |
A |
T |
G |
T |
G |
A |
G |
A |
A |
G |
- |
- |
- |
A |
A |
A |
- |
- |
T |
T |
G |
G |
C |
C |
A |
- |
C |
C |
T |
G |
A |
G |
G |
2 |
T |
G |
C |
G |
2 |
C |
C |
A |
T |
T |
- |
T |
C |
A |
- |
A |
C |
C |
112 |
10 |
T |
C |
A |
G |
- |
- |
T |
- |
T |
T |
A |
- |
C |
27 |
22 |
C |
C |
T |
T |
A |
A |
G |
A |
T |
16 |
A |
T |
C |
G |
T |
G |
A |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
T
|
T
|
-
|
A
|
C
|
G
|
-
|
-
|
A
|
-
|
-
|
T
|
C
|
2
|
T
|
A
|
C
|
G
|
A
|
G
|
G
|
C
|
G
|
A
|
A
|
C
|
-
|
2
|
A
|
T
|
G
|
T
|
G
|
T
|
A
|
2
|
A
|
T
|
A
|
G
|
C
|
C
|
G
|
T
|
G
|
A
|
C
|
A
|
G
|
2
|
G
|
G
|
12
|
A
|
-
|
T
|
G
|
A
|
A
|
-
|
A
|
A
|
T
|
G
|
T
|
G
|
T
|
A
|
T
|
G
|
C
|
A
|
A
|
C
|
-
|
T
|
G
|
G
|
T
|
G
|
C
|
A
|
-
|
C
|
A
|
T
|
T
|
A
|
-
|
T
|
G/-
|
-
|
G
|
G
|
A
|
T
|
A
|
T
|
T
|
A
|
C
|
C
|
-
|
A
|
C
|
T
|
T
|
C
|
G
|
C
|
A
|
G
|
C
|
-
|
-
|
C
|
A
|
C
|
A
|
T
|
G
|
T
|
A
|
C
|
C
|
C
|
T
|
T
|
-
|
T
|
A
|
G
|
A
|
G
|
G
|
A
|
G
|
T
|
G
|
A
|
T
|
T
|
G
|
C
|
C
|
T
|
G
|
A
|
T
|
A
|
C
|
-
|
G
|
T
|
C
|
T
|
A
|
G
|
G
|
G
|
G
|
G
|
G
|
T
|
G
|
A
|
A
|
T
|
2
|
C
|
T
|
-
|
T
|
-
|
-
|
T
|
-
|
-
|
A
|
C
|
C
|
A
|
A
|
A
|
G
|
G
|
C
|
T
|
C
|
C
|
G
|
T
|
-
|
G
|
T
|
T
|
T
|
G
|
G
|
C
|
C
|
2
|
G
|
A
|
T
|
G
|
T
|
G
|
G
|
C
|
C
|
C
|
A
|
G
|
A
|
G
|
T
|
T
|
2
|
16
|
C
|
T
|
G
|
G
|
C
|
-/C
|
C
|
T/-
|
G/T
|
G/A
|
T
|
G
|
G
|
G
|
T
|
T
|
-
|
-
|
G
|
A
|
G/-
|
-
|
G
|
A
|
T
|
T
|
-
|
A
|
T
|
C
|
C
|
C
|
T
|
C
|
T
|
-
|
9
|
G
|
T
|
T
|
-
|
-
|
C
|
G
|
G
|
A
|
A
|
33/T
|
C
|
A
|
-
|
A
|
G
|
T
|
T
|
-
|
-
|
A
|
T
|
C
|
C
|
G
|
G
|
A
|
G
|
A
|
-
|
T
|
C
|
-
|
-
|
C
|
C
|
G
|
|