|
.003 |
.0 |
.0 |
.014 |
.0 |
.013 |
.001 |
.003 |
.001 |
.002 |
.048 |
.029 |
.027 |
.002 |
.038 |
.262 |
.0 |
.008 |
.004 |
.005 |
.005 |
.37 |
.011 |
.0 |
.0 |
.0 |
.0 |
.001 |
.027 |
.009 |
.389 |
.0 |
.0 |
.0 |
.0 |
.0 |
.017 |
.003 |
.034 |
.042 |
.049 |
.023 |
.584 |
-- |
-- |
.55 |
.332 |
.038 |
.462 |
.001 |
.0 |
.004 |
-- |
.118 |
.33 |
.005 |
.002 |
.002 |
.003 |
.063 |
.423 |
.016 |
.001 |
.005 |
.0 |
.007 |
.0 |
.0 |
.002 |
.002 |
.0 |
.061 |
.002 |
.232 |
.066 |
.001 |
.099 |
.001 |
.045 |
.131 |
.247 |
.0 |
.003 |
.02 |
.004 |
.0 |
.006 |
.004 |
.011 |
.001 |
.033 |
.009 |
.02 |
.0 |
.056 |
.286 |
.107 |
.005 |
.003 |
.002 |
.0 |
.013 |
.0 |
.003 |
-- |
.001 |
.0 |
.0 |
.073 |
.058 |
.036 |
.043 |
.067 |
.047 |
.005 |
.944 |
.703 |
.008 |
.07 |
.909 |
.0 |
.001 |
.0 |
.014 |
.0 |
.0 |
.021 |
.061 |
-- |
.151 |
.007 |
.042 |
.017 |
.053 |
.0 |
.001 |
.086 |
.0 |
.003 |
.0 |
.123 |
.018 |
.001 |
.0 |
.0 |
.026 |
.035 |
.019 |
.016 |
.0 |
.0 |
.002 |
.006 |
.001 |
.026 |
.008 |
.0 |
.0 |
.054 |
.005 |
.028 |
.001 |
.002 |
.004 |
.002 |
.0 |
.009 |
.234 |
.001 |
.013 |
.002 |
.109 |
.0 |
.0 |
.003 |
.0 |
.0 |
.027 |
.0 |
.0 |
.002 |
.0 |
.0 |
.026 |
.086 |
.797 |
.013 |
.0 |
.009 |
.007 |
.006 |
.067 |
.003 |
.01 |
.0 |
.003 |
.0 |
.0 |
.0 |
.0 |
.003 |
.003 |
.0 |
.001 |
.007 |
.014 |
.01 |
.009 |
.002 |
.004 |
.009 |
.0 |
.001 |
.017 |
.002 |
.247 |
.023 |
.011 |
.001 |
.0 |
.0 |
.016 |
.001 |
.024 |
.0 |
.003 |
.0 |
.0 |
.0 |
.004 |
.014 |
.0 |
.015 |
.001 |
.337 |
.0 |
.0 |
.082 |
.7 |
.012 |
.001 |
.003 |
.0 |
.002 |
.0 |
.0 |
.003 |
.024 |
.0 |
.002 |
.0 |
.002 |
.0 |
.0 |
.001 |
.0 |
.404 |
.138 |
.002 |
.018 |
.002 |
.005 |
.002 |
.01 |
.005 |
.002 |
.037 |
.019 |
.001 |
.048 |
.001 |
.007 |
.0 |
.001 |
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
|
Cdc14a
|
Cdc14a
|
Cdc14a
|
Cdc14a
|
Cdc14a
|
Cdc14a
|
Cdc14a
|
Cdc14a
|
Cdc14a
|
Cdc14a
|
Cdc14a
|
Cdc14a
|
Cdc14a
|
Cdc14a
|
Cdc14a
|
Cdc14a
|
Cdc14a
|
Cdc14a
|
Cdc14a
|
Cdc14a
|
Cdc14a
|
Cdc14a
|
Cdc14a
|
Cdc14a
|
Cdc14a
|
Cdc14a
|
Cdc14a
|
Cdc14a
|
|
G |
T |
T |
A |
C |
G |
C |
A |
C |
A |
T |
C |
C |
A |
G |
T |
A |
A |
C |
C |
C |
T |
C |
C |
C |
C |
G |
G |
T |
A |
A |
C |
G |
T |
A |
A |
G |
A |
A |
T |
G |
A |
T |
A |
T |
T |
C |
G |
A |
G |
C |
G |
C |
T |
G |
T |
C |
A |
G |
T |
T |
T |
G |
G |
T |
T |
T |
G |
C |
A |
T |
G |
T |
G |
C |
A |
A |
A |
T |
T |
T |
C |
A |
A |
T |
A |
A |
G |
G |
G |
C |
A |
T |
T |
C |
T |
T |
G |
C |
G |
A |
C |
T |
A |
A |
A |
C |
T |
T |
C |
G |
G |
G |
G |
C |
C |
A |
A |
C |
A |
T |
T |
G |
A |
G |
T |
C |
T |
A |
T |
T |
A |
T |
G |
C |
A |
T |
A |
G |
C |
G |
C |
G |
T |
G |
C |
T |
C |
G |
T |
A |
G |
T |
T |
A |
T |
A |
G |
T |
G |
G |
T |
T |
G |
C |
A |
T |
A |
C |
C |
A |
C |
T |
G |
G |
C |
C |
G |
G |
G |
G |
C |
T |
C |
A |
C |
A |
C |
G |
A |
T |
G |
C |
G |
T |
T |
G |
A |
T |
A |
T |
G |
C |
C |
C |
T |
T |
A |
A |
G |
C |
A |
G |
C |
C |
G |
C |
G |
A |
G |
A |
C |
C |
G |
G |
T |
T |
A |
G |
C |
G |
C |
C |
A |
G |
G |
T |
G |
G |
T |
A |
G |
G |
A |
T |
T |
C |
G |
A |
C |
G |
G |
T |
C |
C |
A |
C |
T |
A |
C |
G |
G |
A |
C |
T |
A |
A |
C |
C |
T |
C |
G |
T |
T |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
C
|
C
|
C
|
G
|
T
|
A
|
T
|
T
|
A
|
G
|
C
|
C/G
|
T
|
T
|
T
|
A
|
G
|
A/T
|
G
|
G
|
G
|
C
|
T
|
T
|
A
|
A
|
C
|
A
|
A
|
G
|
G
|
A
|
A
|
C
|
G
|
G
|
A
|
G
|
G
|
G
|
A
|
G
|
A
|
G
|
C
|
T/C
|
A
|
A
|
G
|
T
|
A
|
A
|
G
|
C
|
A
|
G
|
A
|
G
|
A
|
C
|
A
|
C
|
A
|
A
|
C
|
G
|
C
|
T
|
T
|
G
|
C
|
T
|
C
|
A
|
C/T
|
G
|
G
|
G
|
C
|
G
|
A
|
A
|
G
|
G
|
C
|
G
|
G
|
A
|
T
|
A
|
A
|
G
|
C
|
A
|
T
|
G
|
C
|
A
|
T
|
A
|
G
|
A
|
C
|
T
|
G
|
C
|
T
|
G
|
C
|
C/T
|
A
|
G/A
|
G/T
|
A
|
C/A
|
A
|
G
|
G
|
T
|
G
|
C
|
A
|
C
|
T
|
A
|
C
|
T
|
C
|
G
|
C
|
C
|
G
|
A
|
C
|
T
|
T
|
C
|
G
|
T
|
T
|
A
|
T
|
A
|
C
|
A
|
T
|
A
|
G
|
T
|
G
|
G
|
A
|
C
|
A
|
T
|
C
|
G
|
C
|
C
|
A
|
A
|
C
|
C
|
A
|
T
|
G
|
C
|
C
|
G
|
T
|
C
|
T
|
C
|
A
|
A
|
T
|
T
|
A
|
A
|
A
|
A
|
A
|
C
|
T
|
G
|
T
|
G
|
T
|
T
|
G
|
C
|
A
|
A
|
T
|
G
|
G
|
A
|
G
|
G
|
C
|
G
|
A
|
T
|
T
|
T
|
C
|
T/C
|
G
|
G
|
A
|
T
|
G
|
A
|
T
|
T
|
G/A
|
T
|
A
|
C
|
C
|
G
|
T
|
T
|
C
|
A
|
G
|
C
|
C
|
A
|
T
|
C
|
T
|
A
|
G
|
A
|
A
|
C
|
A
|
A
|
C
|
G
|
A
|
A
|
G
|
C
|
C
|
T
|
A
|
G
|
T
|
A
|
A
|
C
|
T
|
A
|
C
|
T
|
C
|
G
|
C/T
|
A
|
G/A
|
C
|
T
|
G
|
G
|
T
|
G
|
A
|
C
|
T
|
A
|
C
|
C
|
|